Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | adenosine deaminase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0104 | 0.2877 | 1 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0104 | 0.2877 | 0.3086 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Echinococcus granulosus | adenosine deaminase | 0.0104 | 0.2877 | 0.2877 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 0.2877 | 0.5 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.5373 | 0.5764 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.2877 | 0.3086 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0104 | 0.2877 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Brugia malayi | calpain family protein 1 | 0.0182 | 0.9322 | 1 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.019 | 1 | 1 |
Trypanosoma brucei | antigen, putative | 0.0069 | 0 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0104 | 0.2877 | 0.2877 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3676 | 0.3943 |
Plasmodium vivax | adenosine deaminase, putative | 0.0104 | 0.2877 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0134 | 0.5373 | 0.5764 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0134 | 0.5373 | 0.5373 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.019 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 0.2877 | 0.5 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.9322 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Brugia malayi | calpain family protein 1 | 0.0182 | 0.9322 | 1 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Echinococcus multilocularis | calpain A | 0.019 | 1 | 1 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0104 | 0.2877 | 0.2877 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0104 | 0.2877 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0104 | 0.2877 | 0.2877 |
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.7625 | 0.8179 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0182 | 0.9322 | 0.9322 |
Treponema pallidum | adenosine deaminase | 0.0104 | 0.2877 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0104 | 0.2877 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0104 | 0.2877 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0182 | 0.9322 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Onchocerca volvulus | 0.0113 | 0.3676 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.