Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0038 | 0.01 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.078 | 0.101 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.016 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0076 | 0.0149 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.014 | 0.2612 | 0.3968 |
Trypanosoma brucei | aldo/keto reductase, putative | 0.0041 | 0.016 | 0.0132 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.01 | 0.0034 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.0405 | 0.0637 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0041 | 0.0178 | 0.0147 |
Echinococcus granulosus | FTZ F1 alpha | 0.0418 | 0.9517 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.0118 |
Onchocerca volvulus | 0.0108 | 0.1833 | 0.6847 | |
Toxoplasma gondii | aldo-keto reductase | 0.0041 | 0.016 | 0.0329 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0177 | 0.0159 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0187 | 0.3789 | 0.5328 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.078 | 0.071 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0141 | 0.2642 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.2612 | 0.3968 |
Mycobacterium leprae | Conserved hypothetical protein | 0.01 | 0.163 | 0.617 |
Schistosoma mansoni | alpha-glucosidase | 0.0161 | 0.3143 | 0.3091 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0042 | 0.0187 | 0.016 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.01 | 0.0024 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0042 | 0.0187 | 0.0118 |
Toxoplasma gondii | aldo/keto reductase family oxidoreductase | 0.0041 | 0.016 | 0.0329 |
Brugia malayi | NADH-dependent xylose reductase | 0.0041 | 0.016 | 0.0164 |
Schistosoma mansoni | alpha glucosidase | 0.0041 | 0.0178 | 0.0103 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0122 | 0.2169 | 0.2217 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.01 | 0.0093 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0042 | 0.0187 | 0.0435 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.078 | 0.1364 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Brugia malayi | Inositol-1 | 0.0038 | 0.01 | 0.0046 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0041 | 0.0178 | 0.0399 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0042 | 0.0187 | 0.0113 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0076 | 0.0149 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0178 | 0.0309 |
Entamoeba histolytica | aldose reductase, putative | 0.0141 | 0.2642 | 1 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0042 | 0.0187 | 0.016 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0042 | 0.0187 | 0.0435 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0122 | 0.2169 | 0.4054 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0187 | 0.016 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Brugia malayi | ecdysteroid receptor | 0.0042 | 0.0187 | 0.0216 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.01 | 0.0093 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0042 | 0.0187 | 0.0435 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0258 | 0.0193 |
Onchocerca volvulus | 0.0141 | 0.2642 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0318 | 0.7045 | 0.7023 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.078 | 0.071 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0258 | 0.0262 |
Onchocerca volvulus | 0.0042 | 0.0187 | 0.0435 | |
Onchocerca volvulus | 0.0141 | 0.2642 | 1 | |
Plasmodium vivax | aldehyde reductase, putative | 0.0041 | 0.016 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0187 | 0.0216 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0122 | 0.2169 | 0.4054 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0141 | 0.2642 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.078 | 0.071 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0041 | 0.016 | 0.0238 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0041 | 0.0178 | 0.0399 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0141 | 0.2642 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.078 | 0.101 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0177 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.113 | 0.1062 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.078 | 0.101 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.01 | 0.0038 |
Entamoeba histolytica | aldose reductase, putative | 0.0141 | 0.2642 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0122 | 0.2169 | 0.3003 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0141 | 0.2642 | 0.497 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0141 | 0.2642 | 0.4015 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0177 | 0.0159 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0178 | 0.0399 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.0405 | 0.0515 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0258 | 0.0184 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.3003 | 0.592 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0391 | 0.0317 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0042 | 0.0187 | 0.0113 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0245 | 0.5239 | 0.5468 |
Entamoeba histolytica | aldose reductase, putative | 0.0141 | 0.2642 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0329 | 0.0986 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0076 | 0.0149 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0187 | 0.016 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0239 | 0.5073 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0076 | 0.0149 |
Brugia malayi | nuclear receptor NHR-88 | 0.0042 | 0.0187 | 0.0216 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.0405 | 0.0348 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0042 | 0.0187 | 0.016 |
Brugia malayi | steroid hormone receptor | 0.0042 | 0.0187 | 0.0216 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.6466 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0178 | 0.0399 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0405 | 0.0515 |
Schistosoma mansoni | aldo-keto reductase | 0.0141 | 0.2642 | 0.2585 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0187 | 0.0216 |
Giardia lamblia | Aldose reductase | 0.0141 | 0.2642 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.01 | 0.0038 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0141 | 0.2642 | 0.4015 |
Loa Loa (eye worm) | oxidoreductase | 0.0141 | 0.2642 | 0.3681 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0141 | 0.2642 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.0405 | 0.0515 |
Mycobacterium tuberculosis | Conserved protein | 0.0041 | 0.016 | 0.0316 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0187 | 0.0216 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0187 | 0.016 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0402 | 0.0511 |
Echinococcus granulosus | aldo keto reductase family 1, member B4 | 0.0041 | 0.016 | 0.009 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0041 | 0.0178 | 0.0147 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0258 | 0.0193 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0187 | 0.016 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Giardia lamblia | Aldose reductase | 0.0141 | 0.2642 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.078 | 0.071 |
Toxoplasma gondii | aldose reductase, putative | 0.0141 | 0.2642 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0178 | 0.0399 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0178 | 0.0399 |
Loa Loa (eye worm) | oxidoreductase | 0.0141 | 0.2642 | 0.3681 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0041 | 0.016 | 0.0329 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.016 | 0.0329 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0141 | 0.2642 | 0.497 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0076 | 0.0149 |
Mycobacterium ulcerans | oxidoreductase | 0.0141 | 0.2642 | 0.8766 |
Echinococcus multilocularis | voltage gated potassium channel subunit | 0.0041 | 0.016 | 0.0121 |
Echinococcus granulosus | snurportin 1 | 0.0318 | 0.7045 | 0.7382 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0187 | 0.0216 |
Toxoplasma gondii | oxidoreductase, aldo/keto reductase family protein | 0.0041 | 0.016 | 0.0329 |
Loa Loa (eye worm) | oxidoreductase | 0.0141 | 0.2642 | 0.3681 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.0405 | 0.0515 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0187 | 0.0118 |
Echinococcus multilocularis | aldo keto reductase | 0.0141 | 0.2642 | 0.3681 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0295 | 0.6466 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0258 | 0.0353 |
Echinococcus granulosus | aldo keto reductase | 0.0141 | 0.2642 | 0.2718 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0041 | 0.0178 | 0.0199 |
Echinococcus granulosus | aldo keto reductase | 0.0141 | 0.2642 | 0.2718 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0042 | 0.0187 | 0.0118 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0042 | 0.0187 | 0.0216 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Echinococcus granulosus | aldehyde reductase | 0.01 | 0.163 | 0.1646 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0178 | 0.016 |
Onchocerca volvulus | 0.0041 | 0.016 | 0.0329 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.0405 | 0.0331 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0405 | 0.1282 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0187 | 0.3789 | 0.7193 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0141 | 0.2642 | 0.4015 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0258 | 0.0262 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0042 | 0.0187 | 0.0118 |
Entamoeba histolytica | alcohol dehydrogenase, putative | 0.0041 | 0.016 | 0.0238 |
Onchocerca volvulus | 0.0141 | 0.2642 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0041 | 0.016 | 0.0329 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0295 | 0.6466 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.0161 | 0.3143 | 0.3091 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0042 | 0.0187 | 0.0216 |
Brugia malayi | glutamate-cysteine ligase modifier subunit | 0.0041 | 0.016 | 0.0164 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0258 | 0.0184 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.0405 | 0.0515 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Echinococcus multilocularis | aldehyde reductase | 0.01 | 0.163 | 0.223 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0042 | 0.0187 | 0.0216 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0122 | 0.2169 | 0.3003 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0076 | 0.0149 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.078 | 0.0746 |
Echinococcus granulosus | aldo keto reductase | 0.0141 | 0.2642 | 0.2718 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0042 | 0.0187 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0141 | 0.2642 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0391 | 0.061 |
Schistosoma mansoni | nuclear hormone receptor | 0.0042 | 0.0187 | 0.0113 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0041 | 0.0178 | 0.0399 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0187 | 0.0113 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.0405 | 0.0472 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.2169 | 0.3003 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0042 | 0.0187 | 0.0113 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0178 | 0.0399 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.078 | 0.071 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0405 | 0.0515 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0042 | 0.0187 | 0.0216 |
Loa Loa (eye worm) | oxidoreductase | 0.0141 | 0.2642 | 0.3681 |
Onchocerca volvulus | 0.0141 | 0.2642 | 1 | |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0076 | 0.0149 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.01 | 0.0038 |
Mycobacterium leprae | Possible oxidoreductase | 0.0041 | 0.016 | 0.0607 |
Leishmania major | aldo-keto reductase-like protein | 0.0141 | 0.2642 | 0.4015 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.01 | 0.0025 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0041 | 0.016 | 0.0132 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0258 | 0.0184 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0187 | 0.3789 | 0.5328 |
Echinococcus granulosus | voltage gated potassium channel subunit | 0.0041 | 0.016 | 0.009 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Leishmania major | prostaglandin f synthase, putative | 0.0141 | 0.2642 | 0.4015 |
Onchocerca volvulus | 0.0141 | 0.2642 | 1 | |
Trypanosoma brucei | glucosidase, putative | 0.0041 | 0.0178 | 0.016 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.01 | 0.0024 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0391 | 0.0317 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0042 | 0.0187 | 0.0113 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0187 | 0.016 |
Onchocerca volvulus | 0.005 | 0.0391 | 0.1227 | |
Echinococcus granulosus | hypothetical protein | 0.0141 | 0.2642 | 0.2718 |
Brugia malayi | hypothetical protein | 0.0245 | 0.5239 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0187 | 0.3789 | 0.3933 |
Echinococcus multilocularis | snurportin 1 | 0.0318 | 0.7045 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0187 | 0.0216 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.01 | 0.0034 |
Echinococcus multilocularis | aldo keto reductase | 0.0141 | 0.2642 | 0.3681 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0041 | 0.016 | 0.0329 |
Brugia malayi | RNA binding protein | 0.0066 | 0.078 | 0.1364 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.0405 | 0.0472 |
Leishmania major | aldo/keto reductase, putative,aldo/keto reductase family-like protein | 0.0041 | 0.016 | 0.0132 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0178 | 0.0399 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0177 | 0.0159 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0258 | 0.0262 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0042 | 0.0187 | 0.016 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0042 | 0.0187 | 0.016 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0187 | 0.016 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0141 | 0.2642 | 0.497 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0041 | 0.016 | 1 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0076 | 0.0149 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.0405 | 0.0472 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0042 | 0.0187 | 0.0216 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0041 | 0.0178 | 0.016 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.2642 | 0.3681 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.016 | 0.0289 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.078 | 0.101 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0042 | 0.0187 | 0.016 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Schistosoma mansoni | aldo-keto reductase | 0.0141 | 0.2642 | 0.2585 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0141 | 0.2642 | 0.497 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0042 | 0.0187 | 0.0118 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.078 | 0.1364 |
Trypanosoma cruzi | aldo-keto reductase | 0.0141 | 0.2642 | 0.4015 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0042 | 0.0187 | 0.0216 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0405 | 0.1282 |
Schistosoma mansoni | potassium channel beta | 0.0041 | 0.016 | 0.0085 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0122 | 0.2169 | 0.2109 |
Loa Loa (eye worm) | oxidoreductase | 0.0141 | 0.2642 | 0.3681 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0041 | 0.0178 | 0.0109 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.0405 | 0.0348 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.0405 | 0.0515 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0295 | 0.6466 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0141 | 0.2642 | 0.4015 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0076 | 0.0287 |
Schistosoma mansoni | coup transcription factor | 0.0042 | 0.0187 | 0.0113 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.01 | 0.0093 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0076 | 0.0149 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0042 | 0.0187 | 0.016 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0178 | 0.016 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.016 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0405 | 0.1282 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0141 | 0.2642 | 0.5207 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0042 | 0.0187 | 0.0216 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0141 | 0.2642 | 1 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0141 | 0.2642 | 0.4015 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0042 | 0.0187 | 0.0113 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0041 | 0.016 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0041 | 0.0178 | 0.0309 |
Trichomonas vaginalis | alcohol dehydrogenase, putative | 0.0041 | 0.016 | 0.0329 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Loa Loa (eye worm) | hypothetical protein | 0.0245 | 0.5239 | 0.7408 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.014 | 0.2612 | 0.3968 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.01 | 0.0093 |
Brugia malayi | RNA, U transporter 1 | 0.0085 | 0.1252 | 0.2278 |
Mycobacterium ulcerans | hypothetical protein | 0.0155 | 0.3003 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0405 | 0.1282 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0042 | 0.0187 | 0.0216 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0245 | 0.5239 | 0.7408 |
Onchocerca volvulus | 0.0141 | 0.2642 | 1 | |
Schistosoma mansoni | pol-related | 0.0141 | 0.2642 | 0.2585 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.01 | 0.0082 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.01 | 0.0038 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0141 | 0.2642 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0042 | 0.0187 | 0.0113 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0042 | 0.0187 | 0.0113 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.0405 | 0.1282 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0041 | 0.0178 | 0.0399 |
Loa Loa (eye worm) | glutamate-cysteine ligase modifier subunit | 0.0041 | 0.016 | 0.0121 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0076 | 0.0287 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0042 | 0.0187 | 0.0118 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.0405 | 0.0515 |
Brugia malayi | nuclear hormone receptor | 0.0042 | 0.0187 | 0.0216 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0042 | 0.0187 | 0.016 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0141 | 0.2642 | 0.3681 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0141 | 0.2642 | 0.2718 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0187 | 0.3789 | 0.5328 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0041 | 0.016 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0141 | 0.2642 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0076 | 0.0149 |
Echinococcus multilocularis | aldo keto reductase | 0.0141 | 0.2642 | 0.3681 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0318 | 0.7045 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0042 | 0.0187 | 0.0113 |
Echinococcus multilocularis | aldo keto reductase | 0.0141 | 0.2642 | 0.3681 |
Schistosoma mansoni | thyroid hormone receptor | 0.0042 | 0.0187 | 0.0113 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | Displacement of N-(fluorescein-5-yl)-N'-(alpha-D-mannopyranosyloxyethyl)-thiocarbamide from Burkholderia cenocepacia J2315 BC2L-A expressed in Escherichia coli BL21 (DE3) cells up to 666 uM incubated for 3 to 4 hrs by fluorescence polarization assay relative to control | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.