Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Echinococcus granulosus | acetylcholinesterase | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0.0885 | 0.5 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0048 | 0.0885 | 0.0885 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Echinococcus granulosus | acetylcholinesterase | 0.0282 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0048 | 0.0885 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0282 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Schistosoma mansoni | acetylcholinesterase | 0.0048 | 0.0885 | 0.0885 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.6056 | 0.6056 |
Echinococcus multilocularis | acetylcholinesterase | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0.0885 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Schistosoma mansoni | gliotactin | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0282 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0048 | 0.0885 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Echinococcus multilocularis | geminin | 0.0181 | 0.6056 | 0.6056 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Onchocerca volvulus | 0.0048 | 0.0885 | 0.5 | |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0048 | 0.0885 | 0.0885 |
Brugia malayi | Carboxylesterase family protein | 0.0282 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0885 | 0.0885 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 0.6056 | 0.6056 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0048 | 0.0885 | 0.0885 |
Echinococcus granulosus | neuroligin | 0.0048 | 0.0885 | 0.0885 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0048 | 0.0885 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0048 | 0.0885 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | carboxylesterase | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Echinococcus granulosus | carboxylesterase 5A | 0.0282 | 1 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Echinococcus granulosus | geminin | 0.0181 | 0.6056 | 0.6056 |
Onchocerca volvulus | 0.0048 | 0.0885 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0048 | 0.0885 | 0.0885 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0048 | 0.0885 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0048 | 0.0885 | 0.0885 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0885 | 0.0885 |
Brugia malayi | Carboxylesterase family protein | 0.0048 | 0.0885 | 0.0885 |
Echinococcus multilocularis | acetylcholinesterase | 0.0282 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0048 | 0.0885 | 0.0885 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0048 | 0.0885 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0282 | 1 | 1 |
Onchocerca volvulus | 0.0048 | 0.0885 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Efficacy (binding) | 0 % | In vitro efficacy tested on human D4.4 receptor were coexpressed with GRqo5 in HEK293 cells using FLIPR assay (Efficacy relative to 10 microM dopamine) | ChEMBL. | 15239663 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.