Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Slit protein homolog | 0.0787 | 0.2082 | 0.208 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1249 | 0.3349 | 1 |
Onchocerca volvulus | 0.0075 | 0.0131 | 0.0129 | |
Echinococcus granulosus | neurogenic locus notch protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.054 | 0.1406 | 0.1405 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0041 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Giardia lamblia | High cysteine protein | 0.0787 | 0.2082 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.054 | 0.1406 | 0.1405 |
Toxoplasma gondii | hypothetical protein | 0.0042 | 0.0039 | 0.0116 |
Brugia malayi | phosphoinositide-dependent protein kinase I | 0.0349 | 0.0882 | 0.088 |
Trichomonas vaginalis | AGC family protein kinase | 0.0349 | 0.0882 | 0.2028 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Echinococcus multilocularis | microsomal glutathione S transferase 3 | 0.0223 | 0.0535 | 0.0533 |
Schistosoma mansoni | carbonic anhydrase | 0.1249 | 0.3349 | 0.3348 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0041 | 0.0037 | 0.0035 |
Toxoplasma gondii | cytochrome C oxidase subunit IIb, putative | 0.0046 | 0.0051 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0023 | 0.0023 |
Echinococcus multilocularis | slit 2 protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0002 | 0.0002 |
Echinococcus multilocularis | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Plasmodium vivax | cytochrome c oxidase subunit 2, putative | 0.0046 | 0.0051 | 0.175 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | septate junction protein | 0.0787 | 0.2082 | 0.208 |
Onchocerca volvulus | Dual oxidase homolog | 0.3674 | 1 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0037 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.0349 | 0.0882 | 0.088 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0042 | 0.0039 | 0.0037 |
Onchocerca volvulus | 0.0096 | 0.0188 | 0.0186 | |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | notch | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0037 | 0.0037 |
Onchocerca volvulus | 0.3674 | 1 | 1 | |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0041 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0787 | 0.2082 | 0.208 |
Mycobacterium ulcerans | transmembrane cytochrome C oxidase (subunit II) CtaC | 0.0046 | 0.0051 | 0.009 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1249 | 0.3349 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0157 | 0.0356 | 0.0354 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0121 | 0.0255 | 0.0253 |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.007 | 0.0068 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.054 | 0.1406 | 0.1406 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0041 | 0.0037 | 0.0073 |
Schistosoma mansoni | notch | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | lipoxygenase | 0.0121 | 0.0255 | 0.0253 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | notch | 0.0787 | 0.2082 | 0.208 |
Brugia malayi | Animal haem peroxidase family protein | 0.3674 | 1 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.054 | 0.1406 | 0.1405 |
Echinococcus multilocularis | carbonic anhydrase II | 0.1118 | 0.2992 | 0.299 |
Onchocerca volvulus | 0.0069 | 0.0114 | 0.0112 | |
Onchocerca volvulus | Cytochrome c oxidase subunit 2 homolog | 0.0046 | 0.0051 | 0.0048 |
Schistosoma mansoni | microsomal glutathione s-transferase | 0.0223 | 0.0535 | 0.0533 |
Mycobacterium ulcerans | transferase | 0.0069 | 0.0114 | 0.0254 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.3674 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0603 | 0.0603 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0042 | 0.0039 | 0.0037 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0041 | 0.0037 | 0.0035 |
Onchocerca volvulus | 0.0787 | 0.2082 | 0.208 | |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Onchocerca volvulus | 0.0787 | 0.2082 | 0.208 | |
Onchocerca volvulus | Cytochrome c oxidase subunit 2 homolog | 0.0046 | 0.0051 | 0.0048 |
Mycobacterium leprae | PROBABLE TRANSFERASE | 0.0069 | 0.0114 | 0.0341 |
Echinococcus multilocularis | fibropellin Ia | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | protein jagged 2 | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Schistosoma mansoni | notch | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | fibropellin Ia | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0075 | 0.0131 | 0.0129 |
Loa Loa (eye worm) | calcium channel | 0.0041 | 0.0037 | 0.0037 |
Brugia malayi | Trypsin family protein | 0.0114 | 0.0235 | 0.0233 |
Onchocerca volvulus | 0.0042 | 0.0039 | 0.0037 | |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Mycobacterium tuberculosis | Probable serine acetyltransferase CysE (sat) | 0.0072 | 0.0122 | 0.0322 |
Echinococcus granulosus | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0075 | 0.0131 | 0.083 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Schistosoma mansoni | peroxidasin | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Onchocerca volvulus | Putative cubilin | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | peroxidasin | 0.3674 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0129 | 0.0278 | 0.0275 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0042 | 0.0039 | 0.0037 |
Brugia malayi | Blistered cuticle protein 3 | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Schistosoma mansoni | cytochrome-c oxidase | 0.0046 | 0.0051 | 0.0048 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0037 |
Echinococcus granulosus | mitogen activated protein kinase 14 | 0.0132 | 0.0287 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0041 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.1118 | 0.2992 | 1 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Trichomonas vaginalis | conserved hypothetical protein | 0.145 | 0.3901 | 1 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0041 | 0.0037 | 0.0035 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0041 | 0.0037 | 0.0035 |
Plasmodium falciparum | amino acid transporter, putative | 0.0042 | 0.0039 | 0.0172 |
Toxoplasma gondii | MAPEG family protein | 0.0223 | 0.0535 | 0.2513 |
Mycobacterium tuberculosis | Probable transmembrane cytochrome C oxidase (subunit II) CtaC | 0.0046 | 0.0051 | 0.005 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Echinococcus granulosus | protein jagged 2 | 0.0787 | 0.2082 | 0.208 |
Brugia malayi | notch-like transmembrane receptor | 0.0787 | 0.2082 | 0.208 |
Trichomonas vaginalis | conserved hypothetical protein | 0.145 | 0.3901 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.054 | 0.1406 | 0.1405 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0114 | 0.0235 | 0.0233 |
Mycobacterium leprae | Probable transmembrane transport protein | 0.0241 | 0.0586 | 0.1751 |
Onchocerca volvulus | Putative sulfate transporter | 0.0209 | 0.0498 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0046 | 0.005 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0603 | 0.0603 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0042 | 0.0039 | 0.0037 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0042 | 0.0039 | 0.0037 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0132 | 0.0287 | 0.0911 |
Mycobacterium ulcerans | carbonic anhydrase | 0.145 | 0.3901 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.1146 | 0.3067 | 0.3067 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0132 | 0.0287 | 0.0285 |
Echinococcus granulosus | protein jagged 1 | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0787 | 0.2082 | 0.208 |
Onchocerca volvulus | 0.0787 | 0.2082 | 0.208 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0028 | 0.0002 | 0.0002 |
Schistosoma mansoni | lipoxygenase | 0.0084 | 0.0156 | 0.0153 |
Echinococcus granulosus | neural cadherin | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Brugia malayi | Animal haem peroxidase family protein | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0349 | 0.0882 | 0.0882 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Brugia malayi | Kringle domain containing protein | 0.0075 | 0.0131 | 0.0129 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0075 | 0.0131 | 0.0129 |
Echinococcus multilocularis | notch | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Onchocerca volvulus | 0.0114 | 0.0235 | 0.0233 | |
Brugia malayi | Animal haem peroxidase family protein | 0.3674 | 1 | 1 |
Brugia malayi | Animal haem peroxidase family protein | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0248 | 0.0603 | 0.0601 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0041 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | serotonin transporter b | 0.0248 | 0.0603 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Echinococcus granulosus | slit 2 protein | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | mitogen activated protein kinase 11 | 0.0132 | 0.0287 | 0.0285 |
Brugia malayi | GCC2 and GCC3 family protein | 0.0787 | 0.2082 | 0.208 |
Onchocerca volvulus | 0.0042 | 0.0039 | 0.0037 | |
Echinococcus granulosus | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Echinococcus granulosus | protein jagged 2 | 0.0787 | 0.2082 | 0.208 |
Onchocerca volvulus | 0.0248 | 0.0603 | 0.0601 | |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0075 | 0.0131 | 0.0129 |
Brugia malayi | Cadherin domain containing protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | thyroid hormone receptor | 0.0157 | 0.0356 | 0.0354 |
Echinococcus granulosus | protein jagged 1 | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0002 | 0.0002 |
Onchocerca volvulus | Peroxidase homolog | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.3674 | 1 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Brugia malayi | Muscle positioning protein 4 | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0235 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0002 | 0.0002 |
Onchocerca volvulus | Peroxidasin homolog | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Onchocerca volvulus | 0.0042 | 0.0039 | 0.0037 | |
Toxoplasma gondii | hypothetical protein | 0.0042 | 0.0039 | 0.0116 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0037 | 0.0074 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0041 | 0.0037 | 0.0035 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0132 | 0.0287 | 0.0285 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0042 | 0.0039 | 0.0037 |
Onchocerca volvulus | 0.0787 | 0.2082 | 0.208 | |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1249 | 0.3349 | 1 |
Mycobacterium tuberculosis | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) | 0.0167 | 0.0383 | 0.132 |
Plasmodium falciparum | transporter, putative | 0.0042 | 0.0039 | 0.0172 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0075 | 0.0131 | 0.5761 |
Plasmodium falciparum | cytochrome c oxidase subunit 2, putative | 0.0046 | 0.0051 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Trypanosoma brucei | mitogen-activated protein kinase 3, putative | 0.0132 | 0.0287 | 0.0911 |
Schistosoma mansoni | carbonic anhydrase-related | 0.054 | 0.1406 | 0.1405 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0787 | 0.2082 | 0.208 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.0996 | 0.2655 | 1 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0349 | 0.0882 | 0.088 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0041 | 0.0037 | 0.0105 |
Brugia malayi | follicle stimulating hormone receptor | 0.0247 | 0.0601 | 0.0599 |
Entamoeba histolytica | acetyltransferase, putative | 0.0072 | 0.0122 | 0.0254 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0041 | 0.0037 | 0.0035 |
Echinococcus granulosus | geminin | 0.0173 | 0.04 | 0.0398 |
Plasmodium vivax | amine transporter, putative | 0.0042 | 0.0039 | 0.1193 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0042 | 0.0039 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | animal heme peroxidase | 0.3674 | 1 | 1 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0042 | 0.0039 | 1 |
Toxoplasma gondii | hypothetical protein | 0.054 | 0.1406 | 0.6731 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0075 | 0.0131 | 0.0388 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.1118 | 0.2992 | 0.299 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0002 | 0.0002 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0157 | 0.0356 | 0.0354 |
Onchocerca volvulus | 0.3674 | 1 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | mitogen activated protein kinase 11 | 0.0132 | 0.0287 | 0.0285 |
Trichomonas vaginalis | AGC family protein kinase | 0.0349 | 0.0882 | 0.2028 |
Loa Loa (eye worm) | animal heme peroxidase | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0129 | 0.0278 | 0.0275 |
Onchocerca volvulus | Cytochrome c oxidase subunit 2 homolog | 0.0046 | 0.0051 | 0.0048 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0247 | 0.0601 | 0.0601 |
Mycobacterium ulcerans | hypothetical protein | 0.0041 | 0.0037 | 0.0056 |
Schistosoma mansoni | notch | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | neural cadherin | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | serotonin transporter | 0.0248 | 0.0603 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Echinococcus granulosus | carbonic anhydrase II | 0.1118 | 0.2992 | 0.299 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1118 | 0.2992 | 0.299 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0116 |
Leishmania major | carbonic anhydrase-like protein | 0.1118 | 0.2992 | 0.892 |
Echinococcus multilocularis | mitogen activated protein kinase 14 | 0.0132 | 0.0287 | 0.0285 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0248 | 0.0603 | 0.0603 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0114 | 0.0235 | 0.0233 |
Echinococcus granulosus | serotonin transporter | 0.0248 | 0.0603 | 0.0601 |
Onchocerca volvulus | 0.0787 | 0.2082 | 0.208 | |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1118 | 0.2992 | 0.299 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | peroxidasin | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Echinococcus multilocularis | protein jagged 1 | 0.0787 | 0.2082 | 0.208 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0116 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0042 | 0.0039 | 0.0037 |
Onchocerca volvulus | 0.0209 | 0.0498 | 0.0495 | |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.04 | 0.0398 |
Echinococcus multilocularis | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Loa Loa (eye worm) | notch protein | 0.0787 | 0.2082 | 0.2082 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0041 | 0.0037 | 0.0074 |
Onchocerca volvulus | 0.0046 | 0.0051 | 0.0048 | |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.0349 | 0.0882 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.0603 | 0.0603 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.054 | 0.1406 | 0.1406 |
Brugia malayi | Protein kinase domain containing protein | 0.0349 | 0.0882 | 0.088 |
Schistosoma mansoni | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Schistosoma mansoni | cytochrome c oxidase subunit II | 0.0125 | 0.0266 | 0.0264 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0787 | 0.2082 | 0.208 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0167 | 0.0383 | 0.0946 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.04 | 0.0398 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0349 | 0.0882 | 0.0882 |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.3674 | 1 | 1 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0787 | 0.2082 | 0.208 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1249 | 0.3349 | 0.858 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0129 | 0.0278 | 0.0275 |
Onchocerca volvulus | Peroxidase homolog | 0.3674 | 1 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0028 | 0.0002 | 0.0002 |
Echinococcus granulosus | delta-like protein 1 | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | carbonic anhydrase | 0.054 | 0.1406 | 0.1405 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0787 | 0.2082 | 0.208 |
Onchocerca volvulus | 0.3674 | 1 | 1 | |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1118 | 0.2992 | 1 |
Wolbachia endosymbiont of Brugia malayi | cytochrome c oxidase, subunit 2 | 0.0152 | 0.0342 | 1 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0121 | 0.0255 | 0.0253 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Echinococcus granulosus | dynactin 5 p25 | 0.0072 | 0.0122 | 0.0119 |
Onchocerca volvulus | Peroxidasin homolog | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1118 | 0.2992 | 0.2992 |
Leishmania major | hypothetical protein, conserved | 0.0075 | 0.0131 | 0.0282 |
Brugia malayi | hypothetical protein | 0.0042 | 0.0039 | 0.0037 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1118 | 0.2992 | 1 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0696 | 0.1832 | 0.6855 |
Wolbachia endosymbiont of Brugia malayi | 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase | 0.0072 | 0.0122 | 0.2761 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0075 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | CMGC/MAPK/P38 protein kinase | 0.0132 | 0.0287 | 0.0287 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.054 | 0.1406 | 0.1405 |
Entamoeba histolytica | protein kinase, putative | 0.0349 | 0.0882 | 0.255 |
Toxoplasma gondii | hypothetical protein | 0.0036 | 0.0023 | 0.0039 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1118 | 0.2992 | 0.299 |
Brugia malayi | Delta serrate ligand family protein | 0.0787 | 0.2082 | 0.208 |
Brugia malayi | EGF-like domain containing protein | 0.0787 | 0.2082 | 0.208 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0787 | 0.2082 | 0.208 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0787 | 0.2082 | 1 |
Leishmania major | mitogen-activated protein kinase 3, putative,map kinase 3, putative | 0.0132 | 0.0287 | 0.0753 |
Brugia malayi | P38 map kinase family protein 2 | 0.0132 | 0.0287 | 0.0285 |
Schistosoma mansoni | slit | 0.0787 | 0.2082 | 0.208 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.054 | 0.1406 | 0.1405 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0041 | 0.0037 | 0.0035 |
Brugia malayi | Animal haem peroxidase family protein | 0.3674 | 1 | 1 |
Plasmodium falciparum | carbonic anhydrase | 0.054 | 0.1406 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.3674 | 1 | 1 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.1118 | 0.2992 | 0.2992 |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | hypothetical protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | carbonic anhydrase-related | 0.054 | 0.1406 | 0.1405 |
Brugia malayi | Protein kinase domain containing protein | 0.0075 | 0.0131 | 0.0129 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0041 | 0.0037 | 0.0035 |
Onchocerca volvulus | Cytochrome c oxidase subunit 2 homolog | 0.0046 | 0.0051 | 0.0048 |
Trypanosoma cruzi | mitogen-activated protein kinase 3, putative | 0.0132 | 0.0287 | 0.0911 |
Echinococcus granulosus | notch | 0.0787 | 0.2082 | 0.208 |
Echinococcus granulosus | microsomal glutathione S transferase 3 | 0.0223 | 0.0535 | 0.0533 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0235 | 0.0235 |
Schistosoma mansoni | membrane associated proteins in eicosanoid and glutathione metabolism family member | 0.0972 | 0.2589 | 0.2587 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0039 | 0.0039 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0041 | 0.0037 | 0.0073 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0041 | 0.0037 | 0.0074 |
Brugia malayi | Cadherin domain containing protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | carbonic anhydrase-related | 0.054 | 0.1406 | 0.1405 |
Echinococcus granulosus | peroxidasin | 0.3674 | 1 | 1 |
Brugia malayi | Peroxidasin | 0.3674 | 1 | 1 |
Echinococcus granulosus | cytochrome c oxidase subunit II | 0.0152 | 0.0342 | 0.034 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0041 | 0.0037 | 0.0035 |
Echinococcus multilocularis | protein jagged 1 | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0131 | 0.0129 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0041 | 0.0037 | 0.0035 |
Wolbachia endosymbiont of Brugia malayi | N-acetylglucosamine-1-phosphate uridyltransferase | 0.0072 | 0.0122 | 0.2761 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0023 | 0.0023 |
Loa Loa (eye worm) | Notch2 | 0.0787 | 0.2082 | 0.2082 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0248 | 0.0603 | 0.0601 |
Trichomonas vaginalis | AGC family protein kinase | 0.0349 | 0.0882 | 0.2028 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0041 | 0.0037 | 0.0035 |
Schistosoma mansoni | voltage-gated cation channel | 0.0041 | 0.0037 | 0.0035 |
Mycobacterium tuberculosis | Probable conserved transmembrane protein | 0.0241 | 0.0586 | 0.2097 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.054 | 0.1406 | 0.1406 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0042 | 0.0039 | 0.0039 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0248 | 0.0603 | 0.5 |
Echinococcus multilocularis | geminin | 0.0173 | 0.04 | 0.0398 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0042 | 0.0039 | 0.0037 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0248 | 0.0603 | 0.0601 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.0106 | 0.0216 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Entamoeba histolytica | ankyrin, putative | 0.0072 | 0.0122 | 0.0255 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0248 | 0.0603 | 0.0603 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0037 | 0.0037 |
Plasmodium vivax | hypothetical protein, conserved | 0.0042 | 0.0039 | 0.1193 |
Loa Loa (eye worm) | animal heme peroxidase | 0.3674 | 1 | 1 |
Toxoplasma gondii | kringle domain-containing protein | 0.0075 | 0.0131 | 0.0559 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0075 | 0.0131 | 0.0129 |
Schistosoma mansoni | cell polarity protein | 0.0787 | 0.2082 | 0.208 |
Schistosoma mansoni | notch | 0.0787 | 0.2082 | 0.208 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0795 | 0.2104 | 0.7893 |
Loa Loa (eye worm) | hypothetical protein | 0.0787 | 0.2082 | 0.2082 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 35 uM | Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 35-40 | ChEMBL. | 8254617 |
IC50 (binding) | = 35 uM | Inhibitory activity of compound against mammalian ribonucleotide reductase; Range is 35-40 | ChEMBL. | 8254617 |
RI (binding) | = 24 % | Relative inhibitory potency against mammalian ribonucleotide reductase | ChEMBL. | 8254617 |
RI (binding) | = 24 % | Relative inhibitory potency against mammalian ribonucleotide reductase | ChEMBL. | 8254617 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.