Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | amidase, putative | 0.0082 | 0.1013 | 0.6757 |
Loa Loa (eye worm) | amidase | 0.0082 | 0.1013 | 0.095 |
Mycobacterium tuberculosis | Probable amidase AmiA2 (aminohydrolase) | 0.0082 | 0.1013 | 0.4053 |
Loa Loa (eye worm) | amidase | 0.0082 | 0.1013 | 0.095 |
Brugia malayi | Cell death protein 3 precursor | 0.0069 | 0.0828 | 0.0828 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0047 | 0.0486 | 0.7223 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0082 | 0.1013 | 0.095 |
Brugia malayi | steroid hormone receptor | 0.0019 | 0.007 | 0.007 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.002 | 0.0079 | 0.001 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0019 | 0.0019 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0019 | 0.007 | 0.007 |
Plasmodium vivax | sentrin-specific protease 1, putative | 0.0047 | 0.0486 | 0.4356 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0353 | 0.5109 | 1 |
Mycobacterium tuberculosis | Probable amidase AmiC (aminohydrolase) | 0.0082 | 0.1013 | 0.4053 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.013 | 0.1747 | 0.6914 |
Giardia lamblia | Sentrin specific protease, putative | 0.0047 | 0.0486 | 0.0809 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.015 | 0.0754 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.045 | 0.0384 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.0069 | 0.0828 | 0.0763 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0486 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0486 | 0.0419 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.015 | 0.0754 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0502 | 0.7356 | 0.7337 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0486 | 0.0809 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.045 | 0.0384 |
Echinococcus granulosus | caspase 3 apoptosis cysteine peptidase | 0.012 | 0.159 | 0.1531 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0032 | 0.0264 | 0.1339 |
Brugia malayi | Muscleblind-like protein | 0.0162 | 0.2221 | 0.2221 |
Leishmania major | SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative | 0.0047 | 0.0486 | 0.4356 |
Echinococcus multilocularis | apoptotic protease activating factor 1 | 0.0037 | 0.0344 | 0.0276 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0057 | 0.0643 | 0.6031 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0047 | 0.0486 | 0.7223 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.021 | 0.2944 | 0.2894 |
Trichomonas vaginalis | sentrin/sumo-specific protease, senp8, putative | 0.0047 | 0.0486 | 0.0809 |
Echinococcus granulosus | histone lysine N methyltransferase NSD3 | 0.004 | 0.0378 | 0.0311 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0019 | 0.007 | 0.007 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0047 | 0.0486 | 0.0419 |
Chlamydia trachomatis | deubiquitinase/deneddylase Dub2 | 0.0047 | 0.0486 | 0.4356 |
Echinococcus granulosus | expressed conserved protein | 0.0163 | 0.2238 | 0.2184 |
Plasmodium falciparum | glutathione reductase | 0.0057 | 0.0643 | 0.6031 |
Wolbachia endosymbiont of Brugia malayi | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0082 | 0.1013 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0145 | 0.1966 | 0.819 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0019 | 0.007 | 0.007 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0384 | 0.5411 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0082 | 0.1013 | 0.095 |
Mycobacterium tuberculosis | Probable amidase AmiB2 (aminohydrolase) | 0.0082 | 0.1013 | 0.4053 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.045 | 0.0384 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0384 | 0.0317 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0384 | 0.0317 |
Schistosoma mansoni | amidase | 0.0677 | 1 | 1 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0057 | 0.0643 | 0.0577 |
Trypanosoma cruzi | metacaspase 5, putative | 0.0032 | 0.0264 | 0.1339 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0145 | 0.1966 | 0.819 |
Echinococcus granulosus | glutamyl tRNAGln amidotransferase subunit A | 0.0082 | 0.1013 | 0.095 |
Echinococcus multilocularis | sentrin specific protease 8 | 0.0111 | 0.1462 | 0.1402 |
Mycobacterium ulcerans | amidase | 0.0082 | 0.1013 | 0.4053 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Mycobacterium tuberculosis | Possible amidase (aminohydrolase) | 0.0082 | 0.1013 | 0.4053 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0019 | 0.007 | 0.007 |
Onchocerca volvulus | Cell death protein 3 homolog | 0.0069 | 0.0828 | 1 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0486 |
Echinococcus multilocularis | caspase 8 | 0.0032 | 0.0264 | 0.0196 |
Trypanosoma cruzi | hypothetical protein | 0.0111 | 0.1462 | 1 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.021 | 0.2944 | 0.5418 |
Echinococcus granulosus | sentrin specific protease 1 | 0.0047 | 0.0486 | 0.0419 |
Chlamydia trachomatis | deubiquitinase/deneddylase Dub1 | 0.0047 | 0.0486 | 0.4356 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0298 | 0.4283 | 0.4242 |
Brugia malayi | hypothetical protein | 0.0024 | 0.015 | 0.015 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.2221 | 0.2167 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0019 | 0.007 | 0.007 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Brugia malayi | putative amidase | 0.0082 | 0.1013 | 0.1013 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0082 | 0.1013 | 0.095 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0019 | 0.007 | 0.007 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0502 | 0.7356 | 0.7337 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0019 | 0.007 | 0.007 |
Trypanosoma cruzi | SUMO1/Ulp2, putative | 0.0047 | 0.0486 | 0.2943 |
Schistosoma mansoni | SET domain protein | 0.004 | 0.0378 | 0.0311 |
Chlamydia trachomatis | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0082 | 0.1013 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0019 | 0.007 | 0.007 |
Mycobacterium tuberculosis | Probable amidase AmiD (acylamidase) (acylase) | 0.0082 | 0.1013 | 0.4053 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0677 | 1 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.002 | 0.0079 | 0.001 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0502 | 0.7356 | 0.7337 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0344 | 0.0276 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0344 | 0.0344 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0264 | 0.1982 |
Mycobacterium ulcerans | amidase | 0.0082 | 0.1013 | 0.4053 |
Echinococcus multilocularis | caspase 2 | 0.0069 | 0.0828 | 0.0763 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0486 | 0.0809 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0384 | 0.0606 |
Trypanosoma cruzi | metacaspase, putative | 0.0032 | 0.0264 | 0.1339 |
Treponema pallidum | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0082 | 0.1013 | 0.1857 |
Onchocerca volvulus | 0.0047 | 0.0486 | 0.5494 | |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0486 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0162 | 0.2221 | 0.2167 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0264 | 0.0368 |
Plasmodium falciparum | metacaspase-like protein | 0.0032 | 0.0264 | 0.1982 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.015 | 0.0081 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Onchocerca volvulus | 0.0037 | 0.0344 | 0.3618 | |
Trichomonas vaginalis | Sentrin-specific protease, putative | 0.0111 | 0.1462 | 0.2748 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Echinococcus multilocularis | muscleblind protein | 0.0162 | 0.2221 | 0.2167 |
Echinococcus granulosus | sentrin specific protease 7 | 0.021 | 0.2944 | 0.2894 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0057 | 0.0643 | 0.4075 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.013 | 0.1747 | 0.7238 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0111 | 0.1462 | 0.1402 |
Schistosoma mansoni | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0082 | 0.1013 | 0.095 |
Echinococcus granulosus | neuropeptide s receptor | 0.0502 | 0.7356 | 0.7337 |
Echinococcus multilocularis | sentrin specific protease 7 | 0.021 | 0.2944 | 0.2894 |
Trypanosoma brucei | fatty-acid amide hydrolase, putative | 0.0082 | 0.1013 | 1 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0677 | 1 | 1 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0024 | 0.015 | 0.0754 |
Plasmodium vivax | glutamyl-tRNA(Gln) amidotransferase subunit A, putative | 0.0082 | 0.1013 | 1 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0111 | 0.1462 | 0.1462 |
Plasmodium vivax | glutathione reductase, putative | 0.0057 | 0.0643 | 0.6031 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0264 | 0.0368 |
Loa Loa (eye worm) | hypothetical protein | 0.0677 | 1 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.013 | 0.1747 | 0.7238 |
Leishmania major | trypanothione reductase | 0.0057 | 0.0643 | 0.6031 |
Echinococcus granulosus | muscleblind protein | 0.0162 | 0.2221 | 0.2167 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0384 | 0.1323 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0057 | 0.0643 | 0.0577 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0.015 | 0.0754 |
Trypanosoma brucei | metacaspase MCA3 | 0.0032 | 0.0264 | 0.1982 |
Trypanosoma cruzi | amidase, putative | 0.0082 | 0.1013 | 0.6757 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0486 | 0.0419 |
Trypanosoma brucei | metacaspase 5, putative | 0.0032 | 0.0264 | 0.1982 |
Leishmania major | hypothetical protein, conserved | 0.0082 | 0.1013 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase NSD3 | 0.004 | 0.0378 | 0.0311 |
Mycobacterium leprae | PROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A) | 0.0082 | 0.1013 | 0.3357 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0486 | 0.0809 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0677 | 1 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0145 | 0.1966 | 0.7978 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.015 | 0.0509 |
Echinococcus multilocularis | sentrin specific protease 1 | 0.0047 | 0.0486 | 0.0419 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0216 |
Echinococcus multilocularis | expressed conserved protein | 0.0163 | 0.2238 | 0.2184 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0111 | 0.1462 | 0.2748 |
Loa Loa (eye worm) | Ulp1 protease | 0.0111 | 0.1462 | 0.1402 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0384 | 0.3263 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0264 | 0.0368 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0024 | 0.015 | 0.0509 |
Mycobacterium ulcerans | aspartyl/glutamyl-tRNA amidotransferase subunit A | 0.0082 | 0.1013 | 0.4053 |
Schistosoma mansoni | caspase-3 (C14 family) | 0.012 | 0.159 | 0.1531 |
Echinococcus multilocularis | glutamyl tRNA(Gln) amidotransferase subunit A | 0.0082 | 0.1013 | 0.095 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0057 | 0.0643 | 0.2445 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0172 | 0.2383 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.045 | 0.0384 |
Loa Loa (eye worm) | glutathione reductase | 0.0057 | 0.0643 | 0.0577 |
Trypanosoma brucei | Metacaspase-4 | 0.0032 | 0.0264 | 0.1982 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0384 | 0.3263 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0264 | 0.0368 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0384 | 0.3263 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.045 | 0.0384 |
Trypanosoma brucei | metacaspase | 0.0032 | 0.0264 | 0.1982 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0216 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.045 | 0.0384 |
Mycobacterium tuberculosis | Probable reductase | 0.013 | 0.1747 | 0.7238 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0019 | 0.007 | 0.007 |
Leishmania major | metacaspase, putative | 0.0032 | 0.0264 | 0.1982 |
Brugia malayi | mucosa associated lymphoid tissue lymphoma translocation protein 1 | 0.0032 | 0.0264 | 0.0264 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0216 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0172 | 0.2383 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0384 | 0.2205 |
Echinococcus granulosus | caspase 8 | 0.0032 | 0.0264 | 0.0196 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0024 | 0.015 | 0.125 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0216 |
Mycobacterium leprae | PROBABLE AMIDASE AMIC (AMINOHYDROLASE) | 0.0082 | 0.1013 | 0.3357 |
Echinococcus granulosus | apoptotic protease activating factor 1 | 0.0037 | 0.0344 | 0.0276 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0047 | 0.0486 | 0.0809 |
Trypanosoma brucei | trypanothione reductase | 0.0057 | 0.0643 | 0.6031 |
Echinococcus granulosus | caspase | 0.012 | 0.159 | 0.1531 |
Echinococcus multilocularis | caspase | 0.012 | 0.159 | 0.1531 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.013 | 0.1747 | 0.7238 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0264 | 0.0196 |
Brugia malayi | Amidase family protein | 0.0082 | 0.1013 | 0.1013 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0321 | 0.1048 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0298 | 0.4283 | 0.4242 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0145 | 0.1966 | 0.819 |
Mycobacterium ulcerans | amidase | 0.0082 | 0.1013 | 0.4053 |
Trypanosoma brucei | metacaspase MCA2 | 0.0032 | 0.0264 | 0.1982 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0019 | 0.007 | 0.007 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0486 | 0.0809 |
Loa Loa (eye worm) | hypothetical protein | 0.0275 | 0.3927 | 0.3884 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0384 | 0.0606 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0032 | 0.0264 | 0.3287 |
Mycobacterium ulcerans | amidase | 0.0082 | 0.1013 | 0.4053 |
Mycobacterium ulcerans | peptide amidase, GatA | 0.0082 | 0.1013 | 0.4053 |
Echinococcus granulosus | sentrin specific protease 8 | 0.0111 | 0.1462 | 0.1402 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0384 | 0.0317 |
Plasmodium falciparum | metacaspase 1 | 0.0032 | 0.0264 | 0.1982 |
Brugia malayi | Inositol-1 | 0.004 | 0.0384 | 0.0384 |
Plasmodium vivax | metacaspase 1, putative | 0.0032 | 0.0264 | 0.1982 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.045 | 0.0384 |
Trypanosoma cruzi | metacaspase, putative | 0.0032 | 0.0264 | 0.1339 |
Schistosoma mansoni | subfamily C14A unassigned peptidase (C14 family) | 0.0032 | 0.0264 | 0.0196 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0264 | 0.0368 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.002 | 0.0079 | 0.0079 |
Plasmodium falciparum | thioredoxin reductase | 0.0057 | 0.0643 | 0.6031 |
Toxoplasma gondii | thioredoxin reductase | 0.0057 | 0.0643 | 1 |
Trypanosoma cruzi | metacaspase, putative | 0.0032 | 0.0264 | 0.1339 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0019 | 0.007 | 0.007 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0353 | 0.5109 | 1 |
Brugia malayi | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0047 | 0.0486 | 0.0486 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0019 | 0.007 | 0.007 |
Loa Loa (eye worm) | Ulp1 protease | 0.0047 | 0.0486 | 0.0419 |
Echinococcus granulosus | caspase 2 | 0.0069 | 0.0828 | 0.0763 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0111 | 0.1462 | 0.2748 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Echinococcus granulosus | caspase 3 | 0.0088 | 0.1106 | 0.1044 |
Brugia malayi | nuclear receptor NHR-88 | 0.0019 | 0.007 | 0.007 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.002 | 0.0079 | 0.001 |
Trypanosoma cruzi | metacaspase, putative | 0.0032 | 0.0264 | 0.1339 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0111 | 0.1462 | 0.2748 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0384 | 0.0317 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C48, putative | 0.0047 | 0.0486 | 0.2943 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0677 | 1 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0677 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0264 | 0.0368 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0019 | 0.007 | 0.007 |
Brugia malayi | Amidase family protein | 0.0082 | 0.1013 | 0.1013 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0019 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0828 | 0.0763 |
Brugia malayi | glutathione reductase | 0.0057 | 0.0643 | 0.0643 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0344 | 0.0276 |
Brugia malayi | ecdysteroid receptor | 0.0019 | 0.007 | 0.007 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.045 | 0.0384 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0384 | 0.0317 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.013 | 0.1747 | 0.7238 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0486 | 0.0419 |
Mycobacterium ulcerans | amidase | 0.0082 | 0.1013 | 0.4053 |
Plasmodium falciparum | sentrin-specific protease 1 | 0.0047 | 0.0486 | 0.4356 |
Toxoplasma gondii | Ulp1 protease family, C-terminal catalytic domain-containing protein | 0.0047 | 0.0486 | 0.7223 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0032 | 0.0264 | 0.3287 |
Schistosoma mansoni | family C48 unassigned peptidase (C48 family) | 0.0047 | 0.0486 | 0.0419 |
Toxoplasma gondii | ICE family protease (caspase) p20 domain-containing protein | 0.0032 | 0.0264 | 0.3287 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.045 | 0.045 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0275 | 0.3927 | 0.3927 |
Echinococcus multilocularis | caspase 3, apoptosis cysteine peptidase | 0.012 | 0.159 | 0.1531 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0384 | 0.2205 |
Plasmodium falciparum | glutamyl-tRNA(Gln) amidotransferase subunit A | 0.0082 | 0.1013 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0353 | 0.5109 | 1 |
Echinococcus multilocularis | caspase 3 | 0.0088 | 0.1106 | 0.1044 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0384 | 0.0606 |
Trypanosoma brucei | SUMO1/Ulp2, putative | 0.0047 | 0.0486 | 0.4356 |
Entamoeba histolytica | Ulp1 protease family, C-terminal catalytic domain containing protein | 0.0111 | 0.1462 | 0.228 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0172 | 0.2383 | 1 |
Trichomonas vaginalis | Clan CD, family C14, metacaspase-like cysteine peptidase | 0.0032 | 0.0264 | 0.0368 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.015 | 0.0754 |
Trichomonas vaginalis | Clan CE, family C48, Ulp1-like cysteine peptidase | 0.0047 | 0.0486 | 0.0809 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0057 | 0.0643 | 0.0577 |
Brugia malayi | Thioredoxin reductase | 0.0057 | 0.0643 | 0.0643 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.2221 | 0.2167 |
Schistosoma mansoni | caspase-7 (C14 family) | 0.012 | 0.159 | 0.1531 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0019 | 0.007 | 0.007 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.013 | 0.1747 | 0.7238 |
Plasmodium vivax | sentrin-specific protease 2, putative | 0.0047 | 0.0486 | 0.4356 |
Brugia malayi | nuclear hormone receptor | 0.0019 | 0.007 | 0.007 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.