Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.8593 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.8593 | 0.5 |
Echinococcus multilocularis | musashi | 0.003 | 1 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.8593 | 0.5 |
Schistosoma mansoni | lamin | 0.003 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0028 | 0.8593 | 0.8593 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.8593 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 1 | 0.5 |
Echinococcus multilocularis | lamin | 0.003 | 1 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.003 | 1 | 0.5 |
Onchocerca volvulus | 0.003 | 1 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0018 | 0.1458 | 0.1458 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.8593 | 0.8593 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 1 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.8593 | 0.5 |
Echinococcus granulosus | lamin | 0.003 | 1 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0028 | 0.8593 | 0.5 |
Schistosoma mansoni | lamin | 0.003 | 1 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 1 | 0.5 |
Onchocerca volvulus | 0.003 | 1 | 0.5 | |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.8593 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.8593 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.9606 | 0.9606 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Kd | = 10 uM | Dissociation constant of the compound by non-linear regression analysis | ChEMBL. | 14552790 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.