Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | sex peptide receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | somatostatin receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.1064 | 0.1064 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0156 | 0.8333 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | G protein-coupled receptor | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | fmrfamide receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | allatostatin A receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | adenoreceptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.1952 | 0.1952 |
Echinococcus multilocularis | lamin | 0.0029 | 0.0749 | 0.0749 |
Brugia malayi | GnHR receptor homolog | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | g protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0717 | 0.0861 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.1952 | 0.2342 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | lamin | 0.0029 | 0.0749 | 0.0749 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | lamin | 0.0029 | 0.0749 | 0.0749 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.1952 | 0.1952 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0029 | 0.0749 | 0.0899 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | geminin | 0.0184 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | G-protein coupled receptor | 0.0035 | 0.1064 | 0.1276 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | hypothetical protein | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | Dopamine receptor protein 1 | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.2164 | 0.2597 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0097 | 0.4775 | 0.4775 |
Echinococcus multilocularis | serotonin receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | g protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | neuropeptide s receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.1952 | 0.2342 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0156 | 0.8333 | 0.8333 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | intermediate filament protein | 0.0029 | 0.0749 | 0.0899 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0035 | 0.1064 | 0.1064 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0156 | 0.8333 | 0.5 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0156 | 0.8333 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0029 | 0.0749 | 0.0749 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | g protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1162 | 0.1162 |
Echinococcus multilocularis | g protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | fmrfamide receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | G-protein coupled receptor | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0156 | 0.8333 | 0.8333 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | intermediate filament protein | 0.0029 | 0.0749 | 0.0899 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0029 | 0.0749 | 0.0899 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.1162 | 0.1395 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.2164 | 0.2597 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.2164 | 0.2597 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0035 | 0.1064 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0035 | 0.1064 | 0.1064 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0156 | 0.8333 | 0.5 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0156 | 0.8333 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | Dopamine receptor protein 2 | 0.0035 | 0.1064 | 0.1276 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0156 | 0.8333 | 1 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1162 | 0.1395 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | serotonin receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | sex peptide receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1952 | 0.1952 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | opsin-like receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | intermediate filament proteins | 0.0029 | 0.0749 | 0.0749 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0749 | 0.0899 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | intermediate filament protein | 0.0029 | 0.0749 | 0.0749 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.1952 | 0.1952 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | sulfakinin receptor protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | putative neuropeptide receptor | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | Melatonin receptor type 1A | 0.0035 | 0.1064 | 0.1276 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0035 | 0.1064 | 1 |
Schistosoma mansoni | lamin | 0.0029 | 0.0749 | 0.0749 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0097 | 0.4775 | 0.4775 |
Echinococcus multilocularis | musashi | 0.0029 | 0.0749 | 0.0749 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | Dopamine receptor | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1952 | 0.1952 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | biogenic amine receptor | 0.0035 | 0.1064 | 0.1064 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0156 | 0.8333 | 0.5 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | biogenic amine receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0097 | 0.4775 | 0.4775 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | Serotonin receptor | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | g-protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | AKH receptor | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0097 | 0.4775 | 0.4775 |
Echinococcus multilocularis | fmrfamide receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | opsin-like receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | neuropeptide F receptor | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | follicle stimulating hormone receptor | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | lamin dm0 | 0.0029 | 0.0749 | 0.0749 |
Brugia malayi | RE15519p | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0156 | 0.8333 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | serotonin receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | allatostatin A receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | orexin receptor type 2 | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | ORL1-like opioid receptor | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0035 | 0.1064 | 0.1064 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0156 | 0.8333 | 1 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0156 | 0.8333 | 0.8333 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | myosin xvIII | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | g protein coupled receptor | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | larval opioid receptor | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | neuropeptide F receptor | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | neuropeptide receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2164 | 0.2597 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | Adenosylhomocysteinase | 0.0156 | 0.8333 | 1 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Brugia malayi | Serotonin receptor | 0.0035 | 0.1064 | 0.1276 |
Echinococcus multilocularis | somatostatin receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.1952 | 0.1952 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0035 | 0.1064 | 0.1276 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0035 | 0.1064 | 0.1064 |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Onchocerca volvulus | 0.0035 | 0.1064 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1064 | 0.1064 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.1952 | 0.1952 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0035 | 0.1064 | 0.1064 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0035 | 0.1064 | 0.1064 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0035 | 0.1064 | 0.1064 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1064 | 0.1276 |
Schistosoma mansoni | histamine h1 receptor | 0.0035 | 0.1064 | 0.1064 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 49 % | Effect of the compound on the S-adenosylhomocysteine hydrolase activity | ChEMBL. | 9748360 |
EC50 (functional) | = 3 uM | concentration required to inhibit reovirus-1-induced cytopathicity by 50% in Vero cells | ChEMBL. | 9748360 |
EC50 (functional) | = 6 uM | concentration required to inhibit vaccinia virus-induced cytopathicity by 50% in E6SM cells | ChEMBL. | 9748360 |
EC50 (functional) | = 6 uM | concentration required to inhibit VSV-induced cytopathicity by 50% in E6SM cells | ChEMBL. | 9748360 |
EC50 (functional) | = 6 uM | concentration required to inhibit parainfluenza-3 virus-induced cytopathicity by 50% in Vero cells | ChEMBL. | 9748360 |
EC50 (functional) | > 30 uM | concentration required to inhibit Coxsackie virus B4-induced cytopathicity by 50% in Vero cells | ChEMBL. | 9748360 |
EC50 (functional) | > 30 uM | concentration required to inhibit Sindbis virus -induced cytopathicity by 50% in Vero cells | ChEMBL. | 9748360 |
EC50 (functional) | > 30 uM | concentration required to inhibit Punta Toro virus-induced cytopathicity by 50% in Vero cells | ChEMBL. | 9748360 |
EC50 (functional) | = 45 uM | concentration required to inhibit VSV-induced cytopathicity by 50% in HeLa cells | ChEMBL. | 9748360 |
EC50 (functional) | > 120 uM | concentration required to inhibit HSV-1(KOS)-induced cytopathicity by 50% in E6SM cells | ChEMBL. | 9748360 |
EC50 (functional) | > 120 uM | concentration required to inhibit HSV-2(G)-induced cytopathicity by 50% in E6SM cells | ChEMBL. | 9748360 |
EC50 (functional) | > 120 uM | concentration required to inhibit HSV-1/TK (B2006) or VMW1837-induced cytopathicity by 50% in E6SM cells | ChEMBL. | 9748360 |
EC50 (functional) | = 210 uM | concentration required to inhibit RSV-induced cytopathicity by 50% in HeLa cells | ChEMBL. | 9748360 |
EC50 (functional) | > 300 uM | concentration required to inhibit Coxsackie virus B4-induced cytopathicity by 50% in HeLa cells | ChEMBL. | 9748360 |
Inhibition (binding) | = 56 % | Inhibition of S-adenosylhomocysteine hydrolase at 100 microM concentration was determined from S-adenosylhomocysteine hydrolase activity remaining | ChEMBL. | 9748360 |
Inhibition (binding) | = 62.9 % | Inhibition of S-adenosylhomocysteine hydrolase at 10 microM concentration was determined from enzyme activity remaining | ChEMBL. | 9748360 |
Inhibition (binding) | = 73.2 % | Inhibition of S-adenosylhomocysteine hydrolase at 1 microM concentration was determined from enzyme activity remaining | ChEMBL. | 9748360 |
Inhibition (binding) | = 91 % | Inhibition of S-adenosylhomocysteine hydrolase at 0.1 microM concentration was determined from enzyme activity remaining | ChEMBL. | 9748360 |
k2 (binding) | = 0.49 min-1 | Kinetic constant of the compound calculated from the pseudo-first-order rate constant(k app) for S-adenosylhomocysteine hydrolase inactivation | ChEMBL. | 9748360 |
Ki (binding) | = 3.8 uM | Kinetic constant of the compound calculated from the pseudo-first-order rate constant(k app) for S-adenosylhomocysteine hydrolase inactivation | ChEMBL. | 9748360 |
MIC (functional) | > 120 uM | Minimum inhibitory concentration(MIC) required to elicit a microscopically visible alteration of cell morphology in Vero cells | ChEMBL. | 9748360 |
MIC (functional) | > 300 uM | Minimum inhibitory concentration(MIC) required to elicit a microscopically visible alteration of cell morphology in E6SM cells | ChEMBL. | 9748360 |
MIC (functional) | > 300 uM | Minimum inhibitory concentration(MIC) required to elicit a microscopically visible alteration of cell morphology in HeLa cells | ChEMBL. | 9748360 |
Release (functional) | = 28 % | Enzyme-mediated release of Adenine(Ade) from the compound | ChEMBL. | 9748360 |
Release (functional) | = 70 % | Enzyme-mediated release of halide ions from the compound | ChEMBL. | 9748360 |
Total coenzyme (functional) | = 49 % | NADH content of the enzyme (percentage of total coenzyme) from the compound | ChEMBL. | 9748360 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.