Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.1761 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.1761 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | carboxylesterase | 0.0298 | 0.1657 | 0.1657 |
Leishmania major | cytochrome p450-like protein | 0.0007 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | carboxylesterase | 0.1761 | 1 | 1 |
Onchocerca volvulus | 0.0298 | 0.1657 | 0.5 | |
Schistosoma mansoni | gliotactin | 0.0298 | 0.1657 | 0.1657 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0007 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0298 | 0.1657 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0298 | 0.1657 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0298 | 0.1657 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1761 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | carboxylesterase | 0.0298 | 0.1657 | 0.1657 |
Echinococcus multilocularis | acetylcholinesterase | 0.1761 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Leishmania major | cytochrome p450-like protein | 0.0007 | 0 | 0.5 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | hypothetical protein | 0.1761 | 1 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0007 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.1761 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0298 | 0.1657 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0298 | 0.1657 | 0.1657 |
Onchocerca volvulus | 0.0298 | 0.1657 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.1761 | 1 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.0007 | 0 | 0.5 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0298 | 0.1657 | 0.1657 |
Brugia malayi | Carboxylesterase family protein | 0.0298 | 0.1657 | 0.1657 |
Echinococcus granulosus | acetylcholinesterase | 0.1761 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Echinococcus granulosus | neuroligin | 0.0298 | 0.1657 | 0.1657 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Onchocerca volvulus | 0.0298 | 0.1657 | 0.5 | |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0007 | 0 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0298 | 0.1657 | 1 |
Echinococcus multilocularis | neuroligin | 0.0298 | 0.1657 | 0.1657 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0298 | 0.1657 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0298 | 0.1657 | 0.1657 |
Echinococcus granulosus | carboxylesterase 5A | 0.1761 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Leishmania major | cytochrome p450-like protein | 0.0007 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1761 | 1 | 1 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0007 | 0 | 0.5 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0007 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1761 | 1 | 1 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0298 | 0.1657 | 0.1657 |
Brugia malayi | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0007 | 0 | 0.5 |
Onchocerca volvulus | 0.0298 | 0.1657 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0298 | 0.1657 | 0.1657 |
Trypanosoma brucei | cytochrome P450, putative | 0.0007 | 0 | 0.5 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0007 | 0 | 0.5 |
Onchocerca volvulus | 0.0298 | 0.1657 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Brugia malayi | Carboxylesterase family protein | 0.0298 | 0.1657 | 0.1657 |
Schistosoma mansoni | acetylcholinesterase | 0.0298 | 0.1657 | 0.1657 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0007 | 0 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0298 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.1657 | 0.1657 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.