Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.1505 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | Cytochrome P450 family protein | 0.0024 | 0.0211 | 0.0317 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0083 | 0.2061 | 0.2468 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0087 | 0.219 | 0.219 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0041 | 0.0739 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.1035 | 0.1549 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0087 | 0.219 | 0.2623 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0041 | 0.0739 | 0.0739 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0282 | 0.835 | 1 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0087 | 0.219 | 0.219 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0076 | 0.1849 | 0.1849 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.134 | 0.8722 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.1035 | 0.1035 |
Brugia malayi | nuclear receptor NHR-88 | 0.0041 | 0.0739 | 0.1106 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0041 | 0.0739 | 0.0739 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0988 | 0.1183 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0087 | 0.219 | 0.2623 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0598 | 0.3748 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1 | 0.1498 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Schistosoma mansoni | coup transcription factor | 0.0087 | 0.219 | 0.2623 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.1035 | 0.1549 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0068 | 0.1599 | 0.1599 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1 | 0.1498 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.0598 | 0.2989 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0039 | 0.0675 | 0.0675 |
Schistosoma mansoni | thyroid hormone receptor | 0.0087 | 0.219 | 0.2623 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0988 | 0.1479 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.134 | 0.134 |
Onchocerca volvulus | 0.0049 | 0.0988 | 0.2067 | |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.0598 | 0.2989 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0109 | 0.2893 | 0.2893 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.1035 | 0.6364 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0087 | 0.219 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0041 | 0.0739 | 0.1106 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0041 | 0.0739 | 0.0739 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0041 | 0.0739 | 0.0885 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0087 | 0.219 | 0.219 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.1505 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.1505 | 1 |
Schistosoma mansoni | fatty acid binding protein | 0.0068 | 0.1599 | 0.1915 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0068 | 0.1596 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.134 | 0.5 |
Echinococcus granulosus | voltage gated potassium channel | 0.0024 | 0.0212 | 0.0212 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0046 | 0.0894 | 0.0894 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0076 | 0.1849 | 0.2768 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0024 | 0.0211 | 0.0317 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0024 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.0598 | 0.3748 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0087 | 0.219 | 0.3279 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0024 | 0.0212 | 0.0212 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0087 | 0.219 | 0.3279 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0068 | 0.1596 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0282 | 0.835 | 0.835 |
Schistosoma mansoni | nuclear hormone receptor | 0.0087 | 0.219 | 0.2623 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0068 | 0.1599 | 0.1599 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0598 | 0.0896 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0087 | 0.219 | 0.3279 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.1035 | 0.6364 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0087 | 0.219 | 0.3279 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0675 | 0.101 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0229 | 0.6679 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0087 | 0.219 | 0.219 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0087 | 0.219 | 0.219 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.1035 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0041 | 0.0739 | 0.0885 |
Onchocerca volvulus | 0.0041 | 0.0739 | 0.0421 | |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0087 | 0.219 | 0.3279 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0087 | 0.219 | 0.2623 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0039 | 0.0675 | 0.0675 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0037 | 0.0598 | 0.2989 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0087 | 0.219 | 0.3279 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0087 | 0.219 | 0.2623 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0637 | 0.0637 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.134 | 0.1605 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0087 | 0.219 | 0.2623 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0087 | 0.219 | 0.3279 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0076 | 0.1849 | 0.1849 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.0598 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0037 | 0.0598 | 0.0334 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0087 | 0.219 | 0.3279 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.1505 | 0.1803 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0567 | 0.0567 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0041 | 0.0739 | 0.0739 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0087 | 0.219 | 0.3279 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0068 | 0.1599 | 0.1599 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0567 | 0.0849 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0083 | 0.2061 | 0.2468 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0109 | 0.2893 | 0.2893 |
Schistosoma mansoni | lipoxygenase | 0.0109 | 0.2893 | 0.3464 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.0598 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0087 | 0.219 | 0.219 |
Loa Loa (eye worm) | doublecortin family protein | 0.0039 | 0.0675 | 0.101 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.134 | 0.1605 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0087 | 0.219 | 0.219 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.1035 | 0.6364 |
Brugia malayi | nuclear hormone receptor | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0076 | 0.1849 | 0.2768 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0046 | 0.0894 | 0.1071 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0567 | 0.0567 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.134 | 0.134 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | Doublecortin family protein | 0.0039 | 0.0675 | 0.101 |
Brugia malayi | tailless protein | 0.0041 | 0.0739 | 0.1106 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.1035 | 0.1035 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0087 | 0.219 | 0.2623 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0037 | 0.0598 | 0.2989 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0087 | 0.219 | 0.3279 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0087 | 0.219 | 0.219 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0024 | 0.0212 | 0.0254 |
Schistosoma mansoni | rab6-interacting | 0.0039 | 0.0675 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0065 | 0.1505 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0675 | 0.101 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1035 | 0.6484 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0087 | 0.219 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0508 | 0.076 |
Schistosoma mansoni | polycystin 1-related | 0.0039 | 0.0675 | 0.0808 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0041 | 0.0739 | 0.0739 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.1505 | 0.2254 |
Onchocerca volvulus | 0.0087 | 0.219 | 1 | |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.1505 | 0.1505 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0041 | 0.0739 | 0.0739 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0024 | 0.0212 | 0.0212 |
Schistosoma mansoni | nuclear receptor | 0.0041 | 0.0739 | 0.0885 |
Echinococcus multilocularis | RUN | 0.0039 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0046 | 0.0894 | 0.0894 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0037 | 0.0598 | 0.3748 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0087 | 0.219 | 0.3279 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0041 | 0.0739 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0039 | 0.0675 | 0.5 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0087 | 0.219 | 0.2623 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0039 | 0.0675 | 0.0675 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0037 | 0.0598 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | nuclear hormone receptor | 0.0087 | 0.219 | 0.3279 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0068 | 0.1599 | 0.1599 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1035 | 0.6484 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.1035 | 0.1035 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1035 | 0.6484 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0087 | 0.219 | 0.3279 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0087 | 0.219 | 0.219 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.1505 | 0.1505 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0041 | 0.0739 | 0.0739 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0039 | 0.0675 | 0.5 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.1505 | 0.2254 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0037 | 0.0598 | 0.0598 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0041 | 0.0739 | 0.0739 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0087 | 0.219 | 0.3279 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.134 | 1 |
Schistosoma mansoni | fatty acid binding protein | 0.0068 | 0.1599 | 0.1915 |
Schistosoma mansoni | thyroid hormone receptor | 0.0087 | 0.219 | 0.2623 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0675 | 0.0808 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.1059 | 0.1268 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | rab6-interacting | 0.0039 | 0.0675 | 0.0808 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0041 | 0.0739 | 0.0739 |
Brugia malayi | nuclear receptor NHR-67 | 0.0041 | 0.0739 | 0.1106 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0041 | 0.0739 | 0.0885 |
Brugia malayi | conserved hypotetical protein | 0.0041 | 0.0739 | 0.1106 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0039 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.1545 | 0.2312 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.134 | 1 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0037 | 0.0598 | 0.0716 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1 | 0.1498 |
Schistosoma mansoni | lipoxygenase | 0.0039 | 0.0675 | 0.0808 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.1505 | 1 |
Echinococcus multilocularis | tumor protein p63 | 0.0334 | 1 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.1035 | 0.6364 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0041 | 0.0739 | 0.1106 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0087 | 0.219 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0046 | 0.0894 | 0.1071 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0087 | 0.219 | 0.219 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0087 | 0.219 | 0.2623 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0037 | 0.0598 | 0.0896 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.1035 | 0.6364 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0087 | 0.219 | 0.219 |
Brugia malayi | nuclear receptor RXR | 0.0041 | 0.0739 | 0.1106 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0087 | 0.219 | 0.219 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0046 | 0.0894 | 0.1339 |
Brugia malayi | ecdysteroid receptor | 0.0087 | 0.219 | 0.3279 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0087 | 0.219 | 0.219 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0037 | 0.0598 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0039 | 0.0675 | 0.0675 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.1035 | 0.6364 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.1035 | 0.1035 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0087 | 0.219 | 0.219 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0567 | 0.0679 |
Echinococcus granulosus | FTZ F1 alpha | 0.0087 | 0.219 | 0.219 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0024 | 0.0211 | 0.0317 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0087 | 0.219 | 0.219 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0024 | 0.0212 | 0.0254 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0675 | 0.101 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0567 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0041 | 0.0739 | 0.1106 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | Lipocalin / cytosolic fatty-acid binding protein family protein | 0.0068 | 0.1599 | 0.2394 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0046 | 0.0894 | 0.1339 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.1035 | 0.6484 |
Schistosoma mansoni | loxhd1 | 0.0039 | 0.0675 | 0.0808 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0046 | 0.0894 | 0.1339 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0041 | 0.0739 | 0.0421 |
Brugia malayi | nuclear receptor RXR | 0.0046 | 0.0894 | 0.1339 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0675 | 0.101 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | nuclear receptor NHR-88 | 0.0087 | 0.219 | 0.3279 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0087 | 0.219 | 0.3279 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0087 | 0.219 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0041 | 0.0739 | 0.1106 |
Onchocerca volvulus | 0.0041 | 0.0739 | 0.0421 | |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0087 | 0.219 | 0.3279 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0637 | 0.0637 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0087 | 0.219 | 0.219 |
Brugia malayi | Cytochrome P450 family protein | 0.0024 | 0.0211 | 0.0317 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0087 | 0.219 | 0.3279 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0041 | 0.0739 | 0.0885 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0037 | 0.0598 | 0.0598 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0041 | 0.0739 | 0.1106 |
Brugia malayi | follicle stimulating hormone receptor | 0.0229 | 0.6679 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0236 | 0.6899 | 0.6899 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0039 | 0.0675 | 0.0675 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0024 | 0.0211 | 0.0317 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0508 | 0.0608 |
Loa Loa (eye worm) | lipocalin/cytosolic fatty-acid binding protein family protein | 0.0068 | 0.1599 | 0.2394 |
Schistosoma mansoni | nuclear receptor | 0.0041 | 0.0739 | 0.0885 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.134 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.1035 | 0.1239 |
Brugia malayi | ecdysone receptor | 0.0041 | 0.0739 | 0.1106 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0041 | 0.0739 | 0.0739 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0041 | 0.0739 | 0.0739 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0739 | 0.1106 |
Schistosoma mansoni | zinc finger protein | 0.0041 | 0.0739 | 0.0885 |
Echinococcus granulosus | RUN | 0.0039 | 0.0675 | 0.0675 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0037 | 0.0598 | 0.0716 |
Schistosoma mansoni | nuclear hormone receptor | 0.0041 | 0.0739 | 0.0885 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.1035 | 0.6364 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0024 | 0.0212 | 0.0317 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.1035 | 0.6364 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0212 | 0.0317 |
Brugia malayi | steroid hormone receptor | 0.0087 | 0.219 | 0.3279 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.134 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0087 | 0.219 | 0.3279 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0894 | 0.1339 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0508 | 0.076 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1 | 0.1498 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 0.22 uM | In vitro inhibitory concentration that relaxed KCL induced contraction in rat detrusor strip by 50% | ChEMBL. | 10737753 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.