Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | fructose-bisphosphate aldolase | 0.0312 | 0.3761 | 0.5 |
Brugia malayi | hypothetical protein | 0.0012 | 0.003 | 0.0034 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.0085 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.03 | 0.3612 | 1 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0088 | 0.0972 | 0.0972 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0328 | 0.0907 |
Loa Loa (eye worm) | acetyltransferase | 0.03 | 0.3612 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0229 | 0.0588 |
Schistosoma mansoni | intermediate filament proteins | 0.0055 | 0.0557 | 0.1501 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0234 | 0.2794 | 0.7735 |
Loa Loa (eye worm) | intermediate filament protein | 0.0055 | 0.0557 | 0.1542 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0108 | 0.1224 | 0.3489 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0328 | 0.0907 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0152 | 0.1773 | 0.6384 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0229 | 0.0634 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0029 | 0.0233 | 0.6962 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0229 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0192 | 0.053 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.03 | 0.3612 | 0.3612 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0088 | 0.0972 | 0.2656 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0328 | 0.0862 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0152 | 0.1773 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0328 | 1 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0012 | 0.003 | 0.0127 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0012 | 0.003 | 0.0392 |
Onchocerca volvulus | 0.0029 | 0.0236 | 0.0743 | |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.0085 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0229 | 0.0654 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.1365 | 0.375 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0088 | 0.0974 | 0.253 |
Echinococcus granulosus | lamin dm0 | 0.0055 | 0.0557 | 0.1589 |
Echinococcus granulosus | leukotriene A 4 hydrolase | 0.0234 | 0.2794 | 0.7966 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0446 | 0.1234 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0028 | 0.0229 | 0.0634 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0152 | 0.1773 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0012 | 0.003 | 0.0392 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0251 | 0.0715 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.003 | 0.0082 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0088 | 0.0972 | 0.9983 |
Echinococcus multilocularis | aminopeptidase N | 0.0012 | 0.003 | 0.003 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0063 | 0.0654 | 0.1772 |
Onchocerca volvulus | 0.0055 | 0.0557 | 0.19 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0072 | 0.0198 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0072 | 0.0204 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0328 | 0.0798 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0012 | 0.003 | 0.0069 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0256 | 0.0665 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0497 | 0.1334 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0072 | 0.015 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0088 | 0.0974 | 0.2776 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0288 | 0.3469 | 0.9891 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0031 | 0.0255 | 0.2394 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0328 | 0.0798 |
Plasmodium falciparum | phd finger protein, putative | 0.0088 | 0.0972 | 1 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0028 | 0.0229 | 0.0588 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0446 | 0.1271 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0251 | 0.0251 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.003 | 0.0249 | 0.0711 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0072 | 0.0204 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Echinococcus multilocularis | leukotriene A 4 hydrolase | 0.0234 | 0.2794 | 0.2794 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0328 | 0.3241 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0241 | 0.2884 | 0.2884 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0324 | 0.0788 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0028 | 0.0229 | 0.6817 |
Plasmodium vivax | hypothetical protein, conserved | 0.0088 | 0.0972 | 0.9983 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0072 | 0.015 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0446 | 0.1191 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0328 | 0.1765 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0029 | 0.024 | 0.0619 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0063 | 0.0664 | 0.6762 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0028 | 0.0229 | 0.0588 |
Brugia malayi | hypothetical protein | 0.0241 | 0.2884 | 0.7976 |
Echinococcus granulosus | geminin | 0.0171 | 0.2006 | 0.572 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0012 | 0.003 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0192 | 0.053 |
Onchocerca volvulus | Alhambra homolog | 0.0088 | 0.0972 | 0.3396 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0012 | 0.003 | 0.003 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0328 | 1 |
Loa Loa (eye worm) | cytochrome P450 | 0.0011 | 0.0018 | 0.0049 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0081 | 0.0882 | 0.9046 |
Leishmania major | puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0012 | 0.003 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1756 | 0.4862 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0497 | 0.1377 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0489 | 0.131 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0088 | 0.0974 | 0.253 |
Echinococcus multilocularis | musashi | 0.0055 | 0.0557 | 0.0557 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0012 | 0.003 | 0.0034 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0251 | 0.0649 |
Onchocerca volvulus | 0.0036 | 0.0328 | 0.1073 | |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0028 | 0.0229 | 0.6817 |
Echinococcus granulosus | jumonji domain containing protein | 0.0122 | 0.1402 | 0.3997 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0328 | 0.1127 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0255 | 0.239 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0232 | 0.2768 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0324 | 0.0324 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0018 | 0.0049 |
Brugia malayi | Peptidase family M1 containing protein | 0.0012 | 0.003 | 0.0034 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0251 | 0.0649 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0012 | 0.003 | 0.0034 |
Toxoplasma gondii | aminopeptidase N protein | 0.0012 | 0.003 | 0.0127 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0324 | 0.0788 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0328 | 0.3154 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0036 | 0.0328 | 0.1765 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0182 | 0.2141 | 0.5926 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0324 | 0.0852 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0012 | 0.003 | 0.0392 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0328 | 0.0798 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0072 | 0.0072 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0204 | 0.0565 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0446 | 0.1191 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0036 | 0.0328 | 0.1127 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.003 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0324 | 0.0788 |
Mycobacterium ulcerans | hypothetical protein | 0.0036 | 0.0328 | 0.1765 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0028 | 0.0229 | 0.0634 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.003 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.1365 | 0.378 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0036 | 0.0328 | 0.1127 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0204 | 0.0582 |
Echinococcus multilocularis | lamin dm0 | 0.0055 | 0.0557 | 0.0557 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2006 | 0.5532 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0328 | 0.1765 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0251 | 0.0251 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0012 | 0.003 | 0.0034 |
Brugia malayi | TATA binding protein associated factor | 0.0012 | 0.003 | 0.0034 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0233 | 0.06 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.003 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0036 | 0.0328 | 0.1127 |
Echinococcus multilocularis | peregrin | 0.0095 | 0.1064 | 0.1064 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.0085 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0328 | 0.0907 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0328 | 0.0862 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0012 | 0.003 | 0.0082 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0446 | 0.0446 |
Schistosoma mansoni | lamin | 0.0055 | 0.0557 | 0.1501 |
Brugia malayi | intermediate filament protein | 0.0055 | 0.0557 | 0.1501 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0012 | 0.003 | 0.0392 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0497 | 0.1377 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.003 | 0.0082 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0489 | 0.131 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0012 | 0.003 | 0.0392 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0328 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0291 | 0.3507 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0072 | 0.0198 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.0085 |
Brugia malayi | jmjC domain containing protein | 0.0288 | 0.3469 | 0.9602 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.003 |
Echinococcus granulosus | lamin | 0.0055 | 0.0557 | 0.1589 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0037 | 0.0337 | 0.0888 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0328 | 0.0907 |
Schistosoma mansoni | phd/f-box containing protein | 0.0028 | 0.0229 | 0.0588 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0204 | 0.0204 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0328 | 0.1127 |
Schistosoma mansoni | hypothetical protein | 0.0088 | 0.0972 | 0.2656 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.245 | 0.6783 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0324 | 0.0852 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.0085 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0011 | 0.0018 | 0.005 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0328 | 0.0862 |
Brugia malayi | jmjC domain containing protein | 0.0108 | 0.1224 | 0.3355 |
Schistosoma mansoni | hypothetical protein | 0.0171 | 0.2006 | 0.5532 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0012 | 0.003 | 0.0392 |
Trypanosoma brucei | aminopeptidase, putative | 0.0012 | 0.003 | 0.0392 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0107 | 0.1203 | 0.1203 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0072 | 0.0072 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0328 | 1 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0028 | 0.0229 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0328 | 0.0907 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0055 | 0.0557 | 0.1542 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0328 | 0.0907 |
Mycobacterium tuberculosis | Conserved protein | 0.0036 | 0.0328 | 0.1127 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.003 | 0.0249 | 0.0249 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0108 | 0.1224 | 0.3355 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0072 | 0.0204 |
Schistosoma mansoni | protein phosphatase 2C | 0.0028 | 0.0229 | 0.0588 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0088 | 0.0972 | 0.9983 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0256 | 0.0665 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.0256 | 0.0731 |
Echinococcus granulosus | peregrin | 0.0095 | 0.1064 | 0.3033 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0081 | 0.0882 | 0.2284 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0288 | 0.3469 | 0.3469 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0234 | 0.2794 | 0.7724 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0324 | 0.0852 |
Schistosoma mansoni | jumonji domain containing protein | 0.0028 | 0.0229 | 0.0588 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0328 | 0.0862 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.03 | 0.0786 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0328 | 0.0862 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0028 | 0.0229 | 0.0229 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0072 | 0.015 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0018 | 0.0049 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0088 | 0.0974 | 1 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0028 | 0.0229 | 0.0653 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0972 | 0.2691 |
Brugia malayi | Peptidase family M1 containing protein | 0.0012 | 0.003 | 0.0034 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0012 | 0.003 | 0.0392 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0446 | 0.1191 |
Onchocerca volvulus | 0.0036 | 0.0328 | 0.1073 | |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0251 | 0.0649 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0012 | 0.003 | 0.0392 |
Echinococcus granulosus | intermediate filament protein | 0.0055 | 0.0557 | 0.1589 |
Trypanosoma cruzi | puromycin-sensitive aminopeptidase-like protein, putative | 0.0012 | 0.003 | 0.0392 |
Plasmodium vivax | JmjC domain containing protein | 0.0028 | 0.0229 | 0.211 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0312 | 0.3761 | 1 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0012 | 0.003 | 0.0069 |
Leishmania major | hypothetical protein, conserved | 0.0028 | 0.0229 | 0.6817 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0236 | 0.0607 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0036 | 0.0328 | 0.1127 |
Brugia malayi | AF-10 protein | 0.0029 | 0.0233 | 0.06 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0236 | 0.0653 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0254 | 0.0658 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0328 | 0.0862 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0328 | 0.0328 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.003 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0446 | 0.1271 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0088 | 0.0974 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0012 | 0.003 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.2884 | 0.7986 |
Onchocerca volvulus | 0.0036 | 0.0328 | 0.1073 | |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0012 | 0.003 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0328 | 0.0907 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.024 | 0.0665 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0072 | 0.0072 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0072 | 0.015 |
Brugia malayi | Peptidase family M1 containing protein | 0.0012 | 0.003 | 0.0034 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0011 | 0.0018 | 0.0049 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0328 | 0.0798 |
Onchocerca volvulus | 0.0235 | 0.2805 | 1 | |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0028 | 0.0229 | 0.6817 |
Loa Loa (eye worm) | aminopeptidase N | 0.0012 | 0.003 | 0.0082 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0122 | 0.1402 | 0.1402 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0497 | 0.1334 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0236 | 0.0607 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0012 | 0.003 | 0.0085 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0251 | 0.2342 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0011 | 0.0018 | 0.0049 |
Onchocerca volvulus | 0.0055 | 0.0557 | 0.19 | |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0489 | 0.131 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0088 | 0.0972 | 0.2691 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0229 | 0.0634 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.0256 | 0.0256 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0028 | 0.0229 | 0.0634 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0028 | 0.0229 | 0.221 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0036 | 0.0328 | 0.1765 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.245 | 0.6768 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0328 | 0.0934 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0108 | 0.1224 | 0.3355 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0072 | 0.015 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0012 | 0.003 | 0.0392 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0328 | 0.0798 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0241 | 0.2884 | 0.8224 |
Echinococcus granulosus | aminopeptidase N | 0.0012 | 0.003 | 0.0085 |
Echinococcus multilocularis | phd:f box containing protein | 0.0028 | 0.0229 | 0.0229 |
Echinococcus granulosus | phd:f box containing protein | 0.0028 | 0.0229 | 0.0653 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0055 | 0.0557 | 0.1501 |
Trichomonas vaginalis | set domain proteins, putative | 0.0235 | 0.2805 | 0.7437 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0251 | 0.0695 |
Brugia malayi | Bromodomain containing protein | 0.0095 | 0.1064 | 0.291 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0108 | 0.1224 | 0.3388 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0254 | 0.0703 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0036 | 0.0328 | 0.1127 |
Echinococcus multilocularis | lamin | 0.0055 | 0.0557 | 0.0557 |
Mycobacterium ulcerans | lipase LipD | 0.0036 | 0.0328 | 0.1765 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0324 | 0.0788 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0088 | 0.0972 | 0.2772 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.03 | 0.3612 | 1 |
Onchocerca volvulus | 0.003 | 0.0251 | 0.0797 | |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0233 | 0.2257 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0012 | 0.003 | 0.0392 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0028 | 0.0229 | 0.0653 |
Echinococcus multilocularis | 0.0011 | 0.0018 | 0.0018 | |
Brugia malayi | hypothetical protein | 0.0012 | 0.003 | 0.0034 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0028 | 0.0229 | 0.0229 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0446 | 0.0446 |
Schistosoma mansoni | lamin | 0.0055 | 0.0557 | 0.1501 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0012 | 0.003 | 0.0082 |
Schistosoma mansoni | jumonji domain containing protein | 0.0229 | 0.273 | 0.7547 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.003 | 0.0082 |
Brugia malayi | hypothetical protein | 0.0108 | 0.1217 | 0.3336 |
Trypanosoma brucei | PHD-zinc-finger like domain containing protein, putative | 0.0029 | 0.0233 | 0.6962 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0072 | 0.015 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0012 | 0.003 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0545 | 0.1508 |
Toxoplasma gondii | WD domain, G-beta repeat-containing protein | 0.0029 | 0.0233 | 0.2257 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0251 | 0.0649 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0036 | 0.0328 | 0.1127 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0012 | 0.003 | 0.0127 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0251 | 0.0649 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0324 | 0.0924 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0039 | 0.0357 | 0.0945 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0028 | 0.0229 | 0.0229 |
Mycobacterium ulcerans | beta-lactamase | 0.0036 | 0.0328 | 0.1765 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0229 | 0.0588 |
Onchocerca volvulus | 0.0049 | 0.0489 | 0.1653 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0446 | 0.1191 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0028 | 0.0229 | 0.221 |
Brugia malayi | jmjC domain containing protein | 0.0028 | 0.0229 | 0.0588 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0557 | 0.1542 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.03 | 0.0786 |
Giardia lamblia | PHD finger protein 15 | 0.0088 | 0.0972 | 0.0312 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.03 | 0.0831 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0088 | 0.0974 | 1 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0028 | 0.0229 | 0.2113 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.1365 | 0.378 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0328 | 0.0798 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0036 | 0.0328 | 0.1127 |
Echinococcus multilocularis | geminin | 0.0171 | 0.2006 | 0.2006 |
Brugia malayi | PHD-finger family protein | 0.0088 | 0.0972 | 0.2656 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0251 | 0.2439 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0328 | 0.0907 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0312 | 0.3761 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Change (functional) | = -44 % | Percent change in the plasma glucose concentration of drug-treated db/db mice (4-6 mice, perorally) relative to vehicle at the dose 20 mg/kg. | ChEMBL. | 8831758 |
Change (functional) | = -44 % | Percent change in the plasma glucose concentration of drug-treated db/db mice (4-6 mice, perorally) relative to vehicle at the dose 20 mg/kg. | ChEMBL. | 8831758 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.