Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | 0.0149 | 0.1137 | 0.1725 | |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0334 | 0.3754 | 0.5697 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0134 | 0.0931 | 0.1413 |
Schistosoma mansoni | tyrosine kinase | 0.0255 | 0.2638 | 0.4003 |
Schistosoma mansoni | neuroglian | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Protein kinase domain containing protein | 0.0084 | 0.0222 | 0.0336 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | protein unc-22 | 0.0156 | 0.1239 | 0.188 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Protein kinase domain containing protein | 0.0074 | 0.0089 | 0.0135 |
Echinococcus granulosus | protein kinase C gamma type | 0.0214 | 0.2057 | 0.3122 |
Schistosoma mansoni | titin | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | diacylglycerol kinase theta | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0076 | 0.0115 | 0.0175 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | twitchin | 0.0364 | 0.4169 | 0.6326 |
Schistosoma mansoni | tyrosine kinase | 0.0255 | 0.2638 | 0.4003 |
Echinococcus multilocularis | titin | 0.0154 | 0.1208 | 0.1833 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0156 | 0.1241 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0314 | 0.3462 | 0.5254 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0536 | 0.659 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0208 | 0.1975 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.1913 | 0.2903 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Myb-like DNA-binding domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Prion-like- | 0.0154 | 0.1208 | 0.1833 |
Onchocerca volvulus | Putative titin | 0.0154 | 0.1208 | 0.3404 |
Brugia malayi | kettin | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | protein kinase C | 0.0079 | 0.0154 | 0.0233 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0286 | 0.307 | 0.4659 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.0076 | 0.0115 | 0.0175 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.012 | 0.0183 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0079 | 0.0159 | 0.0241 |
Schistosoma mansoni | subfamily M23B non-peptidase homologue (M23 family) | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0214 | 0.2057 | 0.3122 |
Echinococcus multilocularis | 0.0154 | 0.1208 | 0.1833 | |
Echinococcus granulosus | protein kinase c epsilon type | 0.0307 | 0.3371 | 0.5115 |
Schistosoma mansoni | cell adhesion molecule | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | transfer RNA-Phe | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | hemicentin 1 | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | myotubularin protein 13 | 0.0076 | 0.012 | 0.0183 |
Brugia malayi | Cytochrome P450 family protein | 0.0082 | 0.02 | 0.0304 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0156 | 0.1239 | 0.188 |
Echinococcus multilocularis | N chimaerin | 0.0076 | 0.0115 | 0.0175 |
Schistosoma mansoni | protein kinase C mu | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0209 | 0.199 | 0.302 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0079 | 0.0159 | 0.0241 |
Brugia malayi | Protein kinase c protein 2 | 0.0209 | 0.1987 | 0.3015 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | roundabout 2 | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | cell adhesion molecule | 0.0276 | 0.293 | 0.4446 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0074 | 0.0089 | 0.0135 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.0076 | 0.0115 | 0.0175 |
Schistosoma mansoni | titin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | NDR protein kinase | 0.0079 | 0.0159 | 0.0241 |
Echinococcus multilocularis | Immunoglobulin | 0.0208 | 0.1975 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.293 | 0.4446 |
Onchocerca volvulus | Peroxidasin homolog | 0.0154 | 0.1208 | 0.3404 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0156 | 0.1239 | 0.188 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0159 | 0.3308 |
Schistosoma mansoni | slit | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0079 | 0.0159 | 0.0241 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.017 | 0.1437 | 0.2181 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0209 | 0.199 | 0.302 |
Echinococcus multilocularis | down syndrome cell adhesion | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | titin | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | diacylglycerol kinase | 0.0072 | 0.0058 | 0.0088 |
Echinococcus multilocularis | myotubularin protein 13 | 0.0076 | 0.012 | 0.0183 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0079 | 0.0159 | 0.0241 |
Echinococcus granulosus | roundabout 2 | 0.0221 | 0.2163 | 0.3282 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1976 | 0.2998 |
Loa Loa (eye worm) | Ras association domain family 1 isoform A | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | vesicular amine transporter | 0.0208 | 0.1975 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0847 | 0.1286 |
Schistosoma mansoni | nephrin related | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | roundabout 2 | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | contactin | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0154 | 0.0233 |
Brugia malayi | RhoGAP domain containing protein | 0.0076 | 0.0115 | 0.0175 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0079 | 0.0159 | 0.0241 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Echinococcus granulosus | neuroglian | 0.0362 | 0.4138 | 0.6279 |
Loa Loa (eye worm) | disorganized muscle protein 1 | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0212 | 0.2032 | 0.3083 |
Schistosoma mansoni | tyrosine kinase | 0.0209 | 0.199 | 0.302 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0314 | 0.3462 | 0.5254 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0276 | 0.293 | 0.4446 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0307 | 0.3371 | 0.5115 |
Echinococcus granulosus | Opioid binding protein:cell adhesion molecule | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Variant SH3 domain containing protein | 0.0076 | 0.0115 | 0.0175 |
Loa Loa (eye worm) | raf kinase | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0079 | 0.0159 | 0.0241 |
Schistosoma mansoni | vav2 | 0.008 | 0.0178 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | unc 13 munc13 | 0.0079 | 0.0154 | 0.0233 |
Schistosoma mansoni | hemicentin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | titin | 0.0156 | 0.1239 | 0.188 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Leucine Rich Repeat family protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0206 | 0.1944 | 0.295 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0224 | 0.2194 | 0.3329 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.0076 | 0.0115 | 0.0175 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0082 | 0.02 | 0.0304 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0334 | 0.3754 | 0.5697 |
Echinococcus multilocularis | Diacylglycerol kinase theta | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | protein kinase c eta type | 0.0072 | 0.0058 | 0.0088 |
Brugia malayi | diacylglycerol kinase | 0.0072 | 0.0058 | 0.0088 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0536 | 0.659 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0128 | 0.0847 | 0.1286 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | peroxidasin | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | titin | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Entamoeba histolytica | protein kinase, putative | 0.0079 | 0.0159 | 0.0855 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | Diacylglycerol kinase theta | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Onchocerca volvulus | 0.0208 | 0.1976 | 0.5883 | |
Brugia malayi | Pleckstrin Homology Domain | 0.0076 | 0.012 | 0.0183 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0137 | 0.0974 | 0.1478 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | insulin receptor | 0.0209 | 0.199 | 0.302 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | unc-13 (munc13) | 0.0079 | 0.0154 | 0.0233 |
Echinococcus multilocularis | twitchin | 0.0156 | 0.1239 | 0.188 |
Echinococcus granulosus | titin | 0.0156 | 0.1239 | 0.188 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.5093 | 0.7729 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Onchocerca volvulus | 0.0132 | 0.09 | 0.241 | |
Brugia malayi | C1-like domain containing protein | 0.0206 | 0.1944 | 0.295 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Toxoplasma gondii | AGC kinase | 0.0079 | 0.0159 | 0.0102 |
Echinococcus multilocularis | Opioid binding protein:cell adhesion molecule | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | diacylglycerol kinase theta | 0.0072 | 0.0058 | 0.0088 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | pro neuregulin 2 membrane bound | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0074 | 0.0089 | 0.0135 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0074 | 0.0089 | 0.0135 |
Echinococcus multilocularis | protein kinase c iota type | 0.024 | 0.2428 | 0.3685 |
Schistosoma mansoni | cell adhesion molecule | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | septate junction protein | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | protein kinase c iota type | 0.024 | 0.2428 | 0.3685 |
Loa Loa (eye worm) | hypothetical protein | 0.0378 | 0.4365 | 0.6624 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Loa Loa (eye worm) | animal heme peroxidase | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0128 | 0.0847 | 0.1286 |
Loa Loa (eye worm) | projectin | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0536 | 0.659 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Schistosoma mansoni | serine/threonine kinase | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.0079 | 0.0154 | 0.0233 |
Brugia malayi | Prion-like- | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | unc-13 (munc13) | 0.0079 | 0.0154 | 0.0233 |
Echinococcus multilocularis | peroxidasin | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | cell adhesion molecule | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0212 | 0.2032 | 0.3083 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0286 | 0.307 | 0.4659 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0208 | 0.1975 | 0.2997 |
Schistosoma mansoni | tyrosine kinase | 0.028 | 0.2987 | 0.4533 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0208 | 0.1975 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.3251 | 0.4933 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0079 | 0.0159 | 0.0241 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0221 | 0.2163 | 0.6488 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Disorganized muscle protein 1 | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0208 | 0.1975 | 0.2997 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0152 | 0.1179 | 0.1789 |
Echinococcus multilocularis | raf serine:threonine protein kinase | 0.013 | 0.0882 | 0.1338 |
Brugia malayi | Protein kinase domain containing protein | 0.0079 | 0.0159 | 0.0241 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0212 | 0.2032 | 0.3083 |
Brugia malayi | Prion-like- | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Prion-like- | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0156 | 0.1239 | 0.188 |
Schistosoma mansoni | titin | 0.0156 | 0.1239 | 0.188 |
Loa Loa (eye worm) | hypothetical protein | 0.0371 | 0.4264 | 0.647 |
Onchocerca volvulus | 0.0299 | 0.3251 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | leucine rich repeats and immunoglobulin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | titin | 0.0156 | 0.1239 | 0.188 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0156 | 0.1239 | 0.188 |
Brugia malayi | protein kinase C II. | 0.0307 | 0.3371 | 0.5115 |
Echinococcus granulosus | down syndrome cell adhesion | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | titin | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | titin | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0206 | 0.1944 | 0.295 |
Schistosoma mansoni | roundabout | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | roundabout 2 | 0.043 | 0.5093 | 0.7729 |
Schistosoma mansoni | cell adhesion molecule | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | nephrin | 0.0362 | 0.4138 | 0.6279 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0159 | 0.3308 |
Echinococcus granulosus | insulin growth factor binding | 0.0154 | 0.1208 | 0.1833 |
Entamoeba histolytica | protein kinase, putative | 0.0084 | 0.0222 | 0.1383 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0208 | 0.1975 | 0.2997 |
Echinococcus granulosus | Immunoglobulin | 0.0208 | 0.1975 | 0.2997 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0128 | 0.0847 | 0.1286 |
Echinococcus multilocularis | titin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0212 | 0.2032 | 0.3083 |
Trichomonas vaginalis | AGC family protein kinase | 0.0079 | 0.0159 | 0.3308 |
Brugia malayi | Hr1 repeat family protein | 0.0079 | 0.0159 | 0.0241 |
Echinococcus granulosus | titin | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | tyrosine kinase | 0.0314 | 0.3462 | 0.5254 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0209 | 0.199 | 0.302 |
Onchocerca volvulus | Netrin receptor homolog | 0.0154 | 0.1208 | 0.3404 |
Schistosoma mansoni | tyrosine kinase | 0.0536 | 0.659 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | unc 13 (munc13) | 0.0079 | 0.0154 | 0.0233 |
Echinococcus granulosus | titin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0314 | 0.3462 | 0.5254 |
Echinococcus multilocularis | insulin growth factor binding | 0.0154 | 0.1208 | 0.1833 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0084 | 0.0222 | 0.5 |
Echinococcus multilocularis | Immunoglobulin | 0.0208 | 0.1975 | 0.2997 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.3251 | 0.4933 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0212 | 0.2032 | 0.6065 |
Schistosoma mansoni | tyrosine kinase | 0.0209 | 0.199 | 0.302 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.09 | 0.1366 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Trichomonas vaginalis | AGC family protein kinase | 0.0084 | 0.0222 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Animal haem peroxidase family protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | TK protein kinase | 0.0212 | 0.2032 | 0.3083 |
Echinococcus granulosus | neuroglian | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | RasGEF domain-containing protein | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | nephrin | 0.0221 | 0.2163 | 0.3282 |
Entamoeba histolytica | protein kinase, putative | 0.0084 | 0.0222 | 0.1383 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0307 | 0.3371 | 0.5115 |
Echinococcus granulosus | protein kinase c eta type | 0.0072 | 0.0058 | 0.0088 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | leucine rich repeat containing protein 4 | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Protein kinase domain containing protein | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0286 | 0.307 | 0.4659 |
Echinococcus granulosus | insulin receptor | 0.0209 | 0.199 | 0.302 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0156 | 0.1239 | 0.188 |
Echinococcus granulosus | leucine rich repeats and immunoglobulin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0079 | 0.0159 | 0.0241 |
Echinococcus multilocularis | hemicentin 1 | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.043 | 0.5093 | 0.7729 |
Schistosoma mansoni | cell adhesion molecule | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | hemicentin 1 | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | RhoGAP domain containing protein | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.0076 | 0.0115 | 0.0175 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0307 | 0.3371 | 0.5115 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0079 | 0.0159 | 0.0241 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0228 | 0.2262 | 0.3433 |
Brugia malayi | Protein kinase domain containing protein | 0.0209 | 0.199 | 0.302 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0079 | 0.0159 | 0.0241 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | N chimaerin | 0.0076 | 0.0115 | 0.0175 |
Schistosoma mansoni | titin | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | defective proboscis extension response | 0.0208 | 0.1975 | 0.2997 |
Echinococcus multilocularis | neuroglian | 0.0362 | 0.4138 | 0.6279 |
Echinococcus multilocularis | pro neuregulin 2, membrane bound | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | cell adhesion molecule | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | myosin-binding protein-related | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Ras association domain family 1 isoform A | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.02 | 0.186 | 0.2823 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.0069 | 0.0013 | 0.002 |
Schistosoma mansoni | rac gtpase activating protein | 0.0072 | 0.0058 | 0.0088 |
Echinococcus granulosus | roundabout 2 | 0.043 | 0.5093 | 0.7729 |
Schistosoma mansoni | tyrosine kinase | 0.0314 | 0.3462 | 0.5254 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0221 | 0.2163 | 0.3282 |
Echinococcus granulosus | titin | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | raf serine:threonine protein kinase | 0.013 | 0.0882 | 0.1338 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Brugia malayi | protein kinase C3,putative | 0.0163 | 0.1345 | 0.2041 |
Echinococcus granulosus | roundabout 2 | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.0079 | 0.0154 | 0.0233 |
Schistosoma mansoni | titin | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0286 | 0.307 | 0.4659 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0084 | 0.0222 | 0.0336 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | tyrosine kinase | 0.0255 | 0.2638 | 0.4003 |
Echinococcus granulosus | nephrin | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | protein kinase C mu | 0.0206 | 0.1944 | 0.295 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Loa Loa (eye worm) | one IG domain family member | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0079 | 0.0159 | 0.0241 |
Onchocerca volvulus | 0.0156 | 0.1239 | 0.3504 | |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Onchocerca volvulus | 0.0204 | 0.1913 | 0.5681 | |
Echinococcus multilocularis | Rac GTPase activating protein 1 | 0.0072 | 0.0058 | 0.0088 |
Onchocerca volvulus | 0.0154 | 0.1208 | 0.3404 | |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | lachesin | 0.0221 | 0.2163 | 0.3282 |
Entamoeba histolytica | protein kinase, putative | 0.0079 | 0.0159 | 0.0855 |
Brugia malayi | Wrapper/rega-1/klingon homolog protein 1 | 0.0154 | 0.1208 | 0.1833 |
Echinococcus granulosus | Rac GTPase activating protein 1 | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.09 | 0.1366 |
Onchocerca volvulus | Peroxidasin homolog | 0.0154 | 0.1208 | 0.3404 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0079 | 0.0159 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | serine/threonine protein kinase | 0.013 | 0.0882 | 0.1338 |
Loa Loa (eye worm) | hypothetical protein | 0.0299 | 0.3251 | 0.4933 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0208 | 0.1975 | 0.2997 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0079 | 0.0159 | 0.0241 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0074 | 0.0089 | 0.0135 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Schistosoma mansoni | septate junction protein | 0.0221 | 0.2163 | 0.3282 |
Schistosoma mansoni | atypical protein kinase C | 0.0247 | 0.2521 | 0.3825 |
Brugia malayi | RhoGEF domain containing protein | 0.0072 | 0.0058 | 0.0088 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | lachesin | 0.0221 | 0.2163 | 0.3282 |
Echinococcus multilocularis | neuroglian | 0.0221 | 0.2163 | 0.3282 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0079 | 0.0159 | 0.0241 |
Brugia malayi | Peroxidasin | 0.0221 | 0.2163 | 0.3282 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0058 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0536 | 0.659 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0154 | 0.1208 | 0.1833 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | 0 ug ml-1 | Evaluated for the antiviral activity against Human cytomegalovirus (HCMV) strain AD-169 by the plaque reduction assay; Not tested | ChEMBL. | 2157012 |
ID50 (functional) | > 100 ug ml-1 | Evaluated for the antiviral activity against Herpes simplex virus type 1 (HSV-1) strain BWS by the plaque reduction assay | ChEMBL. | 2157012 |
ID50 (functional) | > 100 ug ml-1 | Evaluated for the antiviral activity against Herpes simplex virus type 2 (HSV-2) with strain G by the plaque reduction assay | ChEMBL. | 2157012 |
ID50 (functional) | = 100 ug ml-1 | Evaluated for the antiviral activity against Vero cells by proliferation assays (in uninfected cells) | ChEMBL. | 2157012 |
Ki (binding) | = 21 uM | Inhibition of human HGPRT | ChEMBL. | 22178188 |
pKa2 (ADMET) | = 7.08 | Evaluated for the dissociation constant | ChEMBL. | 2157012 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.