Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONAL ENZYME PLSC: PUTATIVE L-3-PHOSPHOSERINE PHOSPHATASE (O-PHOSPHOSERI | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.074 | 0.074 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.6552 | 0.6266 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.1245 | 0.1222 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0767 | 0.0671 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 1 | 1 |
Plasmodium falciparum | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Echinococcus granulosus | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0767 | 0.0767 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0767 | 0.0767 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.6552 | 0.6266 |
Wolbachia endosymbiont of Brugia malayi | 1-acyl-sn-glycerol-3-phosphate acyltransferase | 0.0195 | 1 | 0.5 |
Mycobacterium tuberculosis | 1-acylglycerol-3-phosphate O-acyltransferase | 0.0195 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0767 | 0.0742 |
Chlamydia trachomatis | glycerol-3-phosphate acyltransferase | 0.0195 | 1 | 0.5 |
Echinococcus granulosus | Msx-like | 0.0187 | 0.9562 | 0.9561 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.6552 | 0.6543 |
Toxoplasma gondii | acyltransferase domain-containing protein | 0.0195 | 1 | 0.5 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.1245 | 0.0518 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0122 | 0.6016 | 0.6005 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0767 | 0.0742 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0122 | 0.6016 | 0.6005 |
Echinococcus multilocularis | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0767 | 0.0767 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.1245 | 0.1222 |
Echinococcus multilocularis | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Plasmodium vivax | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Echinococcus multilocularis | Phospholipid glycerol acyltransferase | 0.0195 | 1 | 1 |
Mycobacterium ulcerans | bifunctional transmembrane phospholipid biosynthesis enzyme PlsC | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 1 | 1 |
Toxoplasma gondii | acyltransferase domain-containing protein | 0.0195 | 1 | 0.5 |
Schistosoma mansoni | transcription factor | 0.0187 | 0.9562 | 0.9525 |
Echinococcus multilocularis | homeobox | 0.0187 | 0.9562 | 0.9561 |
Onchocerca volvulus | 0.0026 | 0.0767 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0035 | 0.1245 | 0.1154 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0767 | 0.0742 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0767 | 0.0671 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Treponema pallidum | lysophosphatidic acid acyltransferase | 0.0195 | 1 | 0.5 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0767 | 0.0742 |
Leishmania major | 1-acyl-sn-glycerol-3-phosphateacyltransferase-like protein, putative | 0.0195 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.6016 | 0.5685 |
Echinococcus granulosus | lamin | 0.0026 | 0.0767 | 0.0742 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0767 | 0.0742 |
Mycobacterium ulcerans | 1-acylglycerol-3-phosphate O-acyltransferase | 0.0195 | 1 | 0.5 |
Schistosoma mansoni | 1-acyl-sn-glycerol-3-phosphate o-acyltransferase | 0.0195 | 1 | 1 |
Echinococcus granulosus | Phospholipid glycerol acyltransferase | 0.0195 | 1 | 1 |
Trypanosoma cruzi | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.0767 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0026 | 0.0026 |
Loa Loa (eye worm) | acyltransferase | 0.0195 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1245 | 0.0518 |
Trypanosoma brucei | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0102 | 0.0102 |
Echinococcus granulosus | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.9562 | 0.9562 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.