TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 423.465 | Formula: C22H25N5O4
H donors: 3 H acceptors: 3 LogP: 0.3 Rotable bonds: 10
Rule of 5 violations (Lipinski): 1
SMILES: O=C(CC1OCCN(C1=O)NCC(=O)c1ccccc1)NCc1ccc(cc1)C(=N)N
InChi: 1S/C22H25N5O4/c23-21(24)17-8-6-15(7-9-17)13-25-20(29)12-19-22(30)27(10-11-31-19)26-14-18(28)16-4-2-1-3-5-16/h1-9,19,26H,10-14H2,(H3,23,24)(H,25,29)
InChiKey: WXAGOPKYSNCXKK-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Loa Loa (eye worm)	hypothetical protein	0.0024	0.024	0.0185
Mycobacterium leprae	possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ).	0.0033	0.0363	0.5
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0021	0.0207	0.0189
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.0021	0.0207	0.0189
Schistosoma mansoni	thyroid hormone receptor	0.0045	0.0515	0.0577
Echinococcus granulosus	Nuclear hormone receptor HR96	0.0021	0.0207	0.0189
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0045	0.0515	0.0577
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Schistosoma mansoni	nuclear hormone receptor	0.0045	0.0515	0.0577
Leishmania major	aldehyde dehydrogenase, mitochondrial precursor	0.0061	0.0724	1
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0045	0.0515	0.0535
Brugia malayi	conserved hypotetical protein	0.0021	0.0207	0.0152
Trichomonas vaginalis	set domain proteins, putative	0.024	0.303	0.9176
Brugia malayi	orphan nuclear receptor NR2E1	0.0021	0.0207	0.0152
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0021	0.0207	0.0189
Loa Loa (eye worm)	hypothetical protein	0.0024	0.024	0.0185
Loa Loa (eye worm)	O-glycosyl hydrolase family 30 protein	0.0261	0.3301	0.3363
Loa Loa (eye worm)	hypothetical protein	0.0024	0.024	0.0185
Echinococcus granulosus	ecdysone induced protein 78C	0.0045	0.0515	0.0535
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0045	0.0515	0.0535
Schistosoma mansoni	nuclear receptor nhr-48	0.0021	0.0207	0.0232
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0045	0.0515	0.0535
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Trypanosoma brucei	inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0414	0.5
Brugia malayi	nuclear receptor NHR-88	0.0021	0.0207	0.0152
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0029	0.0307	0.0254
Schistosoma mansoni	nuclear receptor	0.0021	0.0207	0.0232
Brugia malayi	ecdysone receptor	0.0021	0.0207	0.0152
Loa Loa (eye worm)	steroid hormone receptor	0.0045	0.0515	0.047
Trichomonas vaginalis	glucosylceramidase, putative	0.018	0.2261	0.6835
Toxoplasma gondii	aldehyde dehydrogenase	0.0061	0.0724	1
Echinococcus multilocularis	microtubule associated protein 2	0.0697	0.8934	1
Brugia malayi	O-Glycosyl hydrolase family 30 protein	0.0261	0.3301	0.3364
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0061	0.0724	1
Brugia malayi	steroid hormone receptor	0.0045	0.0515	0.0472
Brugia malayi	Nuclear hormone receptor E75	0.0021	0.0207	0.0152
Brugia malayi	Nuclear hormone receptor-like 1	0.0024	0.024	0.0186
Echinococcus granulosus	FTZ F1 alpha	0.0045	0.0515	0.0535
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0045	0.0515	0.0577
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0045	0.0515	0.047
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.0021	0.0207	0.0232
Echinococcus multilocularis	aldehyde dehydrogenase, mitochondrial	0.0061	0.0724	0.077
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0414	0.1209
Loa Loa (eye worm)	hypothetical protein	0.0024	0.024	0.0185
Plasmodium vivax	SET domain protein, putative	0.0031	0.033	0.5
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Echinococcus granulosus	cpg binding protein	0.0031	0.0328	0.0324
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Echinococcus granulosus	microtubule associated protein 2	0.0697	0.8934	1
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0045	0.0515	0.0535
Schistosoma mansoni	retinoic acid receptor RXR	0.0045	0.0515	0.0577
Echinococcus multilocularis	inositol monophosphatase 1	0.0037	0.0414	0.0421
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0045	0.0515	0.0577
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0045	0.0515	0.0535
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0024	0.024	0.0269
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0045	0.0515	0.0472
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.0021	0.0207	0.0232
Trichomonas vaginalis	glucosylceramidase, putative	0.0261	0.3301	1
Echinococcus multilocularis	nuclear receptor nhr 48	0.0021	0.0207	0.0189
Loa Loa (eye worm)	nuclear hormone receptor	0.0021	0.0207	0.015
Schistosoma mansoni	cpg binding protein	0.0031	0.0328	0.0367
Schistosoma mansoni	survival motor neuron protein	0.0049	0.0561	0.0628
Entamoeba histolytica	myo-inositol monophosphatase, putative	0.0037	0.0414	0.5
Brugia malayi	Nuclear hormone receptor E75	0.0021	0.0207	0.0152
Brugia malayi	hypothetical protein	0.0024	0.024	0.0186
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0045	0.0515	0.047
Brugia malayi	nuclear receptor NHR-88	0.0045	0.0515	0.0472
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0045	0.0515	0.0472
Schistosoma mansoni	microtubule-associated protein tau	0.0697	0.8934	1
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0045	0.0515	0.0535
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0045	0.0515	0.0577
Brugia malayi	nuclear receptor RXR	0.0021	0.0207	0.0152
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.033	0.0369
Schistosoma mansoni	nuclear receptor	0.0021	0.0207	0.0232
Brugia malayi	nuclear hormone receptor	0.0756	0.9692	1
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0021	0.0207	0.0189
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0031	0.033	0.0326
Echinococcus multilocularis	survival motor neuron protein 1	0.0239	0.3017	0.3347
Schistosoma mansoni	cpg binding protein	0.0029	0.0307	0.0343
Echinococcus granulosus	aldehyde dehydrogenase mitochondrial	0.0061	0.0724	0.077
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Brugia malayi	CXXC zinc finger family protein	0.0029	0.0307	0.0255
Echinococcus multilocularis	dnaJ subfamily B	0.0413	0.5268	0.5878
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0045	0.0515	0.0472
Brugia malayi	nuclear receptor RXR	0.0024	0.024	0.0186
Echinococcus granulosus	histone lysine N methyltransferase MLL3	0.001	0.0062	0.0026
Trichomonas vaginalis	glucosylceramidase, putative	0.0261	0.3301	1
Loa Loa (eye worm)	hypothetical protein	0.0024	0.024	0.0185
Loa Loa (eye worm)	nuclear receptor NHR-67	0.0021	0.0207	0.015
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Brugia malayi	Inositol-1	0.0037	0.0414	0.0367
Brugia malayi	hypothetical protein	0.0239	0.3017	0.3069
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Brugia malayi	Pre-SET motif family protein	0.0211	0.2655	0.2694
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0031	0.033	0.0326
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0045	0.0515	0.0577
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0045	0.0515	0.0535
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.0021	0.0207	0.0189
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0045	0.0515	0.0472
Onchocerca volvulus		0.0045	0.0515	0.0315
Onchocerca volvulus		0.0049	0.0561	0.0362
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0045	0.0515	0.047
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0061	0.0724	1
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0056	0.0656	0.8276
Trichomonas vaginalis	glucosylceramidase, putative	0.0261	0.3301	1
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Brugia malayi	hypothetical protein	0.0024	0.024	0.0186
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0045	0.0515	0.0535
Trichomonas vaginalis	glucosylceramidase, putative	0.0261	0.3301	1
Onchocerca volvulus		0.024	0.303	0.2883
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0045	0.0515	0.0535
Loa Loa (eye worm)	hypothetical protein	0.0734	0.9417	0.9714
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Loa Loa (eye worm)	hypothetical protein	0.0239	0.3017	0.3068
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0211	0.2655	0.2693
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0024	0.024	0.0269
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0414	0.0463
Schistosoma mansoni	hypothetical protein	0.0049	0.0561	0.0628
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0414	0.5
Schistosoma mansoni	coup transcription factor	0.0045	0.0515	0.0577
Echinococcus granulosus	thyroid hormone receptor alpha	0.0021	0.0207	0.0189
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.0021	0.0207	0.0189
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.0021	0.0207	0.0189
Onchocerca volvulus	Bile acid receptor homolog	0.0045	0.0515	0.0315
Schistosoma mansoni	hypothetical protein	0.0413	0.5268	0.5896
Trichomonas vaginalis	glucosylceramidase, putative	0.018	0.2261	0.6835
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0045	0.0515	0.0472
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0021	0.0207	0.0189
Loa Loa (eye worm)	hypothetical protein	0.0031	0.033	0.0278
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0045	0.0515	0.0535
Echinococcus granulosus	histone lysine methyltransferase setb	0.0031	0.033	0.0326
Trichomonas vaginalis	myo inositol monophosphatase, putative	0.0037	0.0414	0.1209
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Brugia malayi	nuclear receptor NHR-67	0.0021	0.0207	0.0152
Brugia malayi	tailless protein	0.0021	0.0207	0.0152
Echinococcus multilocularis	histone lysine N methyltransferase MLL3	0.001	0.0062	0.0026
Brugia malayi	nuclear hormone receptor family member nhr-6	0.0021	0.0207	0.0152
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.033	0.0369
Brugia malayi	hypothetical protein	0.0021	0.0207	0.0152
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0024	0.024	0.0226
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0024	0.024	0.0226
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0008	0.0039	0.0044
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0045	0.0515	0.0472
Echinococcus multilocularis	ecdysone induced protein 78C	0.0045	0.0515	0.0535
Trypanosoma cruzi	myo-inositol-1(or 4)-monophosphatase 1, putative	0.0037	0.0414	0.5
Brugia malayi	hypothetical protein	0.0021	0.0207	0.0152
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0049	0.0561	0.052
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0045	0.0515	0.047
Echinococcus granulosus	inositol monophosphatase 1	0.0037	0.0414	0.0421
Schistosoma mansoni	nuclear hormone receptor	0.0021	0.0207	0.0232
Onchocerca volvulus	Glucosylceramidase homolog	0.0171	0.2142	0.1976
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0045	0.0515	0.0472
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0045	0.0515	0.0577
Onchocerca volvulus		0.0029	0.0307	0.0102
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Schistosoma mansoni	RAR-like nuclear receptor	0.0045	0.0515	0.0577
Brugia malayi	photoreceptor-specific nuclear receptor	0.0045	0.0515	0.0472
Trichomonas vaginalis	glucosylceramidase, putative	0.0261	0.3301	1
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.0756	0.9692	1
Onchocerca volvulus	Protein ultraspiracle homolog	0.0045	0.0515	0.0315
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Schistosoma mansoni	aldehyde dehydrogenase	0.0061	0.0724	0.081
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0031	0.033	0.0369
Loa Loa (eye worm)	inositol-1	0.0037	0.0414	0.0365
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0063	0.0741	0.0829
Schistosoma mansoni	thyroid hormone receptor	0.0045	0.0515	0.0577
Schistosoma mansoni	nuclear hormone receptor	0.0021	0.0207	0.0232
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0024	0.024	0.0185
Loa Loa (eye worm)	DR-78	0.0021	0.0207	0.015
Brugia malayi	Nuclear hormone receptor-like 1	0.0024	0.024	0.0186
Toxoplasma gondii	inositol(myo)-1(or 4)-monophosphatase 2, putative	0.0037	0.0414	0.2135
Schistosoma mansoni	aldehyde dehydrogenase	0.0061	0.0724	0.081
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0515	0.047
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0045	0.0515	0.0472
Trichomonas vaginalis	glucosylceramidase, putative	0.0261	0.3301	1
Brugia malayi	ecdysteroid receptor	0.0045	0.0515	0.0472
Echinococcus granulosus	nuclear receptor nhr 48	0.0021	0.0207	0.0189
Schistosoma mansoni	zinc finger protein	0.0021	0.0207	0.0232
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0045	0.0515	0.047
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0045	0.0515	0.047
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0045	0.0515	0.0535
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0045	0.0515	0.0472
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0045	0.0515	0.0472
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0045	0.0515	0.0535
Trichomonas vaginalis	inositol monophosphatase, putative	0.0037	0.0414	0.1209
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0045	0.0515	0.047
Brugia malayi	nuclear hormone receptor	0.0045	0.0515	0.0472
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0045	0.0515	0.0535
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0045	0.0515	0.0472
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0045	0.0515	0.0577
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Mycobacterium tuberculosis	Probable aldehyde dehydrogenase	0.0061	0.0724	1
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Schistosoma mansoni	inositol monophosphatase	0.0037	0.0414	0.0463
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0045	0.0515	0.0472
Echinococcus multilocularis	FTZ F1 alpha	0.0045	0.0515	0.0535
Brugia malayi	nuclear hormone receptor family member odr-7	0.0021	0.0207	0.0152
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Onchocerca volvulus		0.0031	0.033	0.0125
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0045	0.0515	0.0535
Trichomonas vaginalis	glucosylceramidase, putative	0.0171	0.2142	0.6472
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0031	0.033	0.0369
Brugia malayi	Steroid receptor seven-up type 2	0.0045	0.0515	0.0472
Brugia malayi	Nuclear hormone receptor-like 1	0.0045	0.0515	0.0472
Echinococcus multilocularis	cpg binding protein	0.0031	0.0328	0.0324
Echinococcus granulosus	survival motor neuron protein 1	0.0239	0.3017	0.3347
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0029	0.0307	0.0301
Echinococcus granulosus	dnaJ subfamily B	0.0413	0.5268	0.5878
Brugia malayi	Pre-SET motif family protein	0.0031	0.033	0.0279
Wolbachia endosymbiont of Brugia malayi	fructose-1,6-bisphosphatase	0.0037	0.0414	0.5
Loa Loa (eye worm)	hypothetical protein	0.0021	0.0207	0.015
Mycobacterium ulcerans	aldehyde dehydrogenase	0.0061	0.0724	1
Schistosoma mansoni	cpg binding protein	0.0031	0.0328	0.0367
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0045	0.0515	0.0472
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.0021	0.0207	0.0152

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	> 133 uM	Inhibitory activity against human thrombin	ChEMBL.	12954052

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 314294

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 224491