Detailed information for compound 2256096

Basic information

Technical information
  • TDR Targets ID: 2256096
  • Name: 2-naphthalen-1-yl-1,2-benzothiazol-3-one
  • MW: 277.056 | Formula: C17H11NOS
  • H donors: 0 H acceptors: 1 LogP: 4.16 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 0
  • SMILES: O=c1c2ccccc2sn1c1cccc2c1cccc2
  • InChi: InChI=1S/C17H11NOS/c19-17-14-9-3-4-11-16(14)20-18(17)15-10-5-7-12-6-1-2-8-13(12)15/h1-11H
  • InChiKey: ZZGGLSHLBVZOQU-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(1-naphthyl)-1,2-benzothiazol-3-one

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum basic transcription factor 3b, putative 0.0042 0.0214 0.0572
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0214 0.0391
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0209 0.2278 0.2256
Brugia malayi Cell death protein 3 precursor 0.0032 0.0088 0.0065
Plasmodium falciparum metacaspase-like protein 0.0032 0.0088 0.0156
Echinococcus granulosus PHD finger protein rhinoceros 0.0035 0.0127 0.0099
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0117 0.1144 0.3031
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1315 0.3173
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trypanosoma cruzi heat shock protein 90, putative 0.0047 0.0277 0.0761
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0046 0.0012
Loa Loa (eye worm) hypothetical protein 0.0048 0.0281 0.0744
Loa Loa (eye worm) hypothetical protein 0.0041 0.0201 0.0532
Schistosoma mansoni kinase 0.0058 0.0409 0.0409
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0088 0.0076
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.013 0.0182
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.007 0.0186
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0052 0.0334 0.1644
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1315 0.3144
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0054 0.0364 0.1067
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1103 0.3623
Entamoeba histolytica serine/threonine protein kinase, putative 0.0114 0.1103 0.2643
Trypanosoma brucei transcription factor BTF3, putative 0.0042 0.0214 0.0596
Echinococcus granulosus hexokinase type 2 0.0096 0.0882 0.0855
Plasmodium falciparum heat shock protein 90 0.0055 0.0376 0.1108
Loa Loa (eye worm) hypothetical protein 0.006 0.0436 0.1156
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0599 0.1844
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.016 0.1674 0.4373
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.1315 0.1291
Schistosoma mansoni rab6-interacting 0.0048 0.0281 0.0281
Schistosoma mansoni glucose-6-phosphate 1-dehydrogenase 0.0263 0.2942 0.2942
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0599 0.1494
Echinococcus multilocularis glucose 6 phosphate 1 dehydrogenase 0.0263 0.2942 0.2922
Echinococcus multilocularis thioredoxin glutathione reductase 0.0057 0.0398 0.0371
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.039 0.0831
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0214 0.0391
Plasmodium falciparum mannose-6-phosphate isomerase, putative 0.0117 0.1144 0.3647
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.4058 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0029 0.0046 0.0013
Trypanosoma cruzi heat shock protein 90, putative 0.0055 0.0376 0.1104
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0036 0.0138 0.0319
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.013 0.0008
Brugia malayi 6-phosphofructokinase 0.0131 0.1315 0.1936
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.013 0.0295
Treponema pallidum glucose-6-phosphate 1-dehydrogenase 0.0263 0.2942 0.7222
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0599 0.1494
Trypanosoma brucei metacaspase 0.0032 0.0088 0.0163
Trichomonas vaginalis glutaminase, putative 0.033 0.3775 0.9294
Trichomonas vaginalis heat shock protein, putative 0.0047 0.0277 0.0549
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0052 0.0334 1
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.0678 0.0651
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0054 0.0364 0.0765
Loa Loa (eye worm) hypothetical protein 0.0056 0.0382 0.1012
Echinococcus granulosus histone lysine methyltransferase setb 0.0057 0.0392 0.0365
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Entamoeba histolytica hypothetical protein 0.0042 0.0214 0.0431
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0114 0.1103 0.1077
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Trypanosoma cruzi Glucose-6-phosphate dehydrogenase, putative 0.0085 0.0738 0.2357
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0122
Entamoeba histolytica hexokinase 1 0.0096 0.0882 0.2093
Plasmodium vivax heat shock protein 86, putative 0.0055 0.0376 0.1108
Trypanosoma brucei Putative Phosphatase/Protein of unknown function DUF89, putative 0.0066 0.0505 0.1599
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.013 0.0182
Schistosoma mansoni hypothetical protein 0.0048 0.0281 0.0281
Loa Loa (eye worm) bromodomain containing protein 0.0026 0.0009 0.0023
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0076 0.0637 0.061
Schistosoma mansoni hypothetical protein 0.0205 0.2223 0.2223
Plasmodium vivax basic transcription factor 3b, putative 0.0042 0.0214 0.0572
Mycobacterium tuberculosis Putative ferredoxin reductase 0.013 0.1303 0.7076
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0599 0.1923
Leishmania major hypothetical protein, conserved 0.0257 0.287 0.975
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0599 0.3127
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0117 0.1144 0.1675
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Loa Loa (eye worm) hypothetical protein 0.0057 0.0392 0.104
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.003 0.0058 0.0045
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0599 0.0599
Giardia lamblia Heat shock protein HSP 90-alpha 0.0047 0.0277 0.0382
Plasmodium falciparum LCCL domain-containing protein 0.0048 0.0281 0.0793
Schistosoma mansoni heat shock protein 0.0037 0.0147 0.0147
Toxoplasma gondii phosphomannose isomerase type I protein 0.0117 0.1144 0.3647
Mycobacterium ulcerans mannose-6-phosphate isomerase ManA 0.0117 0.1144 0.2954
Trypanosoma cruzi Putative Phosphatase/Protein of unknown function DUF89, putative 0.0066 0.0505 0.155
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.1315 0.7146
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trypanosoma cruzi Heat shock protein 83, putative 0.0055 0.0376 0.1104
Loa Loa (eye worm) hypothetical protein 0.0053 0.0353 0.0936
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.003 0.0058 0.0093
Echinococcus multilocularis heat shock protein 0.0055 0.0376 0.0349
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0122
Mycobacterium ulcerans hypothetical protein 0.0029 0.0046 0.0013
Toxoplasma gondii heat shock protein HSP90 0.0055 0.0376 0.1108
Schistosoma mansoni lipoxygenase 0.0209 0.2278 0.2278
Loa Loa (eye worm) hypothetical protein 0.0048 0.0281 0.0744
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0029 0.0046 0.0013
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0077 0.0643 0.3377
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0263 0.0235
Brugia malayi serine/threonine-protein kinase plk-2 0.0114 0.1103 0.1612
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0263 0.2942 1
Brugia malayi Bromodomain containing protein 0.0095 0.0865 0.1249
Echinococcus granulosus neuropeptide s receptor 0.0566 0.6697 0.6687
Echinococcus granulosus caspase 2 0.0032 0.0088 0.006
Trichomonas vaginalis heat shock protein, putative 0.0032 0.009 0.008
Trypanosoma cruzi phosphomannose isomerase, putative 0.0117 0.1144 0.3767
Schistosoma mansoni hypothetical protein 0.0205 0.2223 0.2223
Loa Loa (eye worm) thioredoxin reductase 0.0057 0.0398 0.1055
Echinococcus granulosus hexokinase 0.0096 0.0882 0.0855
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.013 0.0182
Plasmodium falciparum glutathione reductase 0.0057 0.0398 0.118
Echinococcus multilocularis endoplasmin 0.0052 0.0334 0.0307
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0273 0.3066 0.7521
Trypanosoma brucei hexokinase, putative 0.0096 0.0882 0.2897
Brugia malayi Hexokinase family protein 0.0096 0.0882 0.1274
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.1315 0.3485
Echinococcus multilocularis citrate lyase subunit beta protein 0.003 0.0058 0.0029
Echinococcus multilocularis RUN 0.0048 0.0281 0.0253
Trichomonas vaginalis heat shock protein, putative 0.004 0.0189 0.0327
Loa Loa (eye worm) glutaminase 2 0.033 0.3775 1
Leishmania major hexokinase, putative 0.0096 0.0882 0.2897
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0281 0.0253
Plasmodium vivax heat shock protein, putative 0.021 0.2286 0.7421
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0029 0.0046 0.0013
Echinococcus granulosus citrate lyase subunit beta protein 0.003 0.0058 0.0029
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.0678 0.1585
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0114 0.1103 0.2921
Chlamydia trachomatis glucose-6-phosphate 1-dehydrogenase 0.0263 0.2942 1
Loa Loa (eye worm) hexokinase 0.006 0.0438 0.1161
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0115 0.1118 0.1093
Brugia malayi glucose-6-phosphate dehydrogenase 0.0263 0.2942 0.4417
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0281 0.0253
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0057 0.0392 0.0365
Trichomonas vaginalis endoplasmin, putative 0.004 0.0189 0.0327
Brugia malayi PHD-finger family protein 0.0034 0.0117 0.0108
Leishmania major basic transcription factor 3a, putative 0.0042 0.0214 0.0596
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.1315 0.3485
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0054 0.0364 0.1067
Trypanosoma brucei polo-like protein kinase 0.0114 0.1103 0.366
Schistosoma mansoni caspase-7 (C14 family) 0.0032 0.0088 0.0088
Onchocerca volvulus 0.0096 0.0882 0.2624
Toxoplasma gondii hexokinase 0.0096 0.0882 0.2779
Onchocerca volvulus Alhambra homolog 0.0035 0.0127 0.0255
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.013 0.0182
Echinococcus multilocularis heat shock protein 90 0.0047 0.0277 0.025
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.013 0.0295
Loa Loa (eye worm) hypothetical protein 0.01 0.0934 0.2473
Plasmodium vivax thioredoxin reductase, putative 0.0057 0.0398 0.118
Giardia lamblia Heat shock protein HSP 90-alpha 0.0055 0.0376 0.0633
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0251 0.2801 0.7419
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.013 0.0182
Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase 0.0273 0.3066 1
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0247 0.022
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0088 0.0156
Trypanosoma cruzi metacaspase, putative 0.0032 0.0088 0.0106
Echinococcus granulosus neuropeptide receptor A26 0.0566 0.6697 0.6687
Echinococcus granulosus heat shock protein 90 0.0047 0.0277 0.025
Trypanosoma cruzi metacaspase, putative 0.0032 0.0088 0.0106
Entamoeba histolytica hypothetical protein 0.0043 0.0229 0.0468
Trypanosoma brucei metacaspase MCA3 0.0032 0.0088 0.0163
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.006 0.0436 0.0596
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Echinococcus multilocularis geminin 0.0205 0.2223 0.2201
Echinococcus multilocularis transcription factor btf3 0.0042 0.0214 0.0186
Plasmodium vivax multidomain scavenger receptor, putative 0.0048 0.0281 0.0793
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.039 0.0831
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.01 0.0934 0.0934
Trypanosoma cruzi metacaspase 5, putative 0.0032 0.0088 0.0106
Plasmodium vivax metacaspase 1, putative 0.0032 0.0088 0.0156
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0334 0.0691
Toxoplasma gondii Hsp90 domain-containing protein 0.021 0.2286 0.7421
Echinococcus granulosus RUN 0.0048 0.0281 0.0253
Echinococcus multilocularis hexokinase 0.0096 0.0882 0.0855
Giardia lamblia Kinase, PLK 0.0114 0.1103 0.2482
Brugia malayi hypothetical protein 0.0048 0.0281 0.0358
Mycobacterium leprae probable mannose-6-phosphate isomerase ManA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHO 0.0064 0.0479 0.2457
Trypanosoma cruzi metacaspase 5, putative 0.0032 0.0088 0.0106
Loa Loa (eye worm) hypothetical protein 0.0031 0.007 0.0186
Entamoeba histolytica acyl-CoA synthetase, putative 0.0029 0.0046 0.0012
Onchocerca volvulus 0.01 0.0934 0.2788
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0247 0.0655
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.013 0.0295
Loa Loa (eye worm) glutaminase 0.033 0.3775 1
Brugia malayi hexokinase type II 0.0031 0.007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0046 0.0265 0.0702
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.013 0.0222
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0032 0.0088 0.0156
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0209 0.2278 0.2256
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0234
Loa Loa (eye worm) hypothetical protein 0.0029 0.0046 0.0122
Echinococcus granulosus histone acetyltransferase KAT2B 0.0054 0.0364 0.0336
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0032 0.0088 0.0065
Echinococcus multilocularis PHD finger protein rhinoceros 0.0035 0.0127 0.0099
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.1315 0.4393
Loa Loa (eye worm) PHD-finger family protein 0.0035 0.0127 0.0337
Echinococcus granulosus mannose 6 phosphate isomerase 0.0117 0.1144 0.1119
Treponema pallidum fructose-bisphosphate aldolase 0.0353 0.4058 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0013
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0057 0.0398 0.2002
Echinococcus multilocularis Polycystic kidney disease protein 0.0048 0.0281 0.0253
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.013 0.0308
Schistosoma mansoni transcription factor btf3 0.0042 0.0214 0.0214
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0036 0.0138 0.0138
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0247 0.0247
Brugia malayi glutaminase DH11.1 0.033 0.3775 0.5687
Treponema pallidum hexokinase (hxk) 0.0096 0.0882 0.2093
Trypanosoma cruzi metacaspase, putative 0.0032 0.0088 0.0106
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0058 0.0045
Leishmania major phosphomannose isomerase 0.0117 0.1144 0.3803
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0046 0.0013
Toxoplasma gondii heat shock protein 90, putative 0.0055 0.0376 0.1108
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0678 0.2195
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0036 0.0138 0.0109
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Trypanosoma cruzi metacaspase, putative 0.0032 0.0088 0.0106
Plasmodium vivax hexokinase, putative 0.0096 0.0882 0.2779
Trypanosoma cruzi heat shock protein, putative 0.0037 0.0147 0.0308
Plasmodium vivax glutathione reductase, putative 0.0057 0.0398 0.118
Onchocerca volvulus 0.0182 0.1949 0.5977
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Echinococcus multilocularis caspase 2 0.0032 0.0088 0.006
Plasmodium falciparum phd finger protein, putative 0.0035 0.0127 0.0285
Entamoeba histolytica hexokinase 2 0.0096 0.0882 0.2093
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0032 0.0088 0.0156
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.01 0.0934 0.1354
Trypanosoma brucei hexokinase 0.0096 0.0882 0.2897
Loa Loa (eye worm) hexokinase 0.0096 0.0882 0.2335
Echinococcus granulosus Polycystic kidney disease protein 0.0048 0.0281 0.0253
Trypanosoma brucei hexokinase 0.0096 0.0882 0.2897
Brugia malayi acetyltransferase, GNAT family protein 0.0178 0.1892 0.2816
Schistosoma mansoni mannose-6-phosphate isomerase 0.0117 0.1144 0.1144
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.013 0.0295
Toxoplasma gondii heat shock protein 75, putative 0.0037 0.0147 0.0348
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0145 0.1483 0.8084
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0054 0.0364 0.1067
Treponema pallidum heat shock protein 90 0.0052 0.0334 0.073
Brugia malayi heat shock protein 90 0.0055 0.0376 0.0504
Giardia lamblia Glucose-6-phosphate 1-dehydrogenase 0.0273 0.3066 0.7477
Plasmodium vivax mannose-6-phosphate isomerase, putative 0.0117 0.1144 0.3647
Trypanosoma brucei glucose-6-phosphate 1-dehydrogenase 0.0263 0.2942 1
Leishmania major hypothetical protein, conserved 0.0066 0.0505 0.1599
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.013 0.1303 0.7076
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0273 0.3066 1
Giardia lamblia Grp94/Hsp90 0.0052 0.0334 0.0526
Echinococcus granulosus zinc finger protein 0.0028 0.0037 0.0009
Echinococcus multilocularis caspase 0.012 0.1175 0.1149
Entamoeba histolytica phosphomannose isomerase, putative 0.0117 0.1144 0.2747
Echinococcus granulosus heat shock protein 90 0.0055 0.0376 0.0349
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.013 0.0295
Schistosoma mansoni heat shock protein 0.0055 0.0376 0.0376
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0037 0.0147 0.0316
Mycobacterium tuberculosis Probable dehydrogenase 0.013 0.1303 0.7076
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.1315 0.4361
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0376 0.1104
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0392 0.0392
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Leishmania major hexokinase, putative 0.0096 0.0882 0.2897
Trichomonas vaginalis glucosamine-6-phosphate isomerase, putative 0.0273 0.3066 0.7521
Echinococcus granulosus peregrin 0.0042 0.0216 0.0188
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0599 0.0572
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0229 0.0201
Brugia malayi jmjC domain containing protein 0.0115 0.1118 0.1635
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0599 0.1494
Echinococcus multilocularis caspase 3 0.0088 0.0778 0.0752
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Loa Loa (eye worm) heat shock protein 90 0.0055 0.0376 0.0997
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0043 0.0229 0.0201
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Trypanosoma cruzi phosphomannose isomerase, putative 0.0117 0.1144 0.3767
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0037 0.0147 0.0118
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0145 0.1483 0.8084
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0088 0.0076
Plasmodium falciparum heat shock protein 90, putative 0.021 0.2286 0.7421
Schistosoma mansoni hexokinase 0.0096 0.0882 0.0882
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0077 0.0643 0.3377
Loa Loa (eye worm) mannose-6-phosphate isomerase 0.0117 0.1144 0.3031
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1315 0.3173
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0046 0.0017
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.0678 0.1796
Brugia malayi latrophilin 2 splice variant baaae 0.0041 0.0201 0.0236
Trypanosoma brucei Heat shock protein 83, putative 0.0055 0.0376 0.1155
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1315 0.3144
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.013 0.1303 0.7076
Trypanosoma cruzi glucose-6-phosphate 1-dehydrogenase, putative 0.0087 0.0769 0.2465
Brugia malayi Pre-SET motif family protein 0.0036 0.0138 0.014
Brugia malayi hexokinase 0.0096 0.0882 0.1274
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0376 0.0834
Brugia malayi Hsp90 protein 0.0037 0.0147 0.0153
Echinococcus granulosus heat shock protein 0.0055 0.0376 0.0349
Plasmodium falciparum histone acetyltransferase GCN5 0.0047 0.0275 0.0775
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0029 0.0046 0.0027
Schistosoma mansoni loxhd1 0.0048 0.0281 0.0281
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0178 0.1892 0.1869
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.003 0.0058 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Echinococcus granulosus transcription factor btf3 0.0042 0.0214 0.0186
Mycobacterium tuberculosis Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD) 0.0091 0.0819 0.4363
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.012 0.1175 0.1149
Mycobacterium ulcerans glutaminase 0.033 0.3775 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0032 0.0088 0.0156
Trypanosoma brucei heat shock protein, putative 0.0055 0.0376 0.1155
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0214 0.0542
Toxoplasma gondii glucose-6-phosphate 1-dehydrogenase 0.0172 0.1815 0.5863
Echinococcus granulosus jumonji domain containing protein 0.0049 0.0298 0.027
Echinococcus granulosus caspase 8 0.0032 0.0088 0.006
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0046 0.0027
Echinococcus multilocularis lysine specific demethylase 5A 0.0043 0.0219 0.0191
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0046 0.0017
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0599 0.0599
Loa Loa (eye worm) ICD-1 protein 0.0042 0.0214 0.0567
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0088 0.0076
Echinococcus multilocularis zinc finger protein 0.0028 0.0037 0.0009
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0178 0.1892 0.1892
Giardia lamblia Histone acetyltransferase GCN5 0.0047 0.0275 0.0377
Trypanosoma brucei hypothetical protein, conserved 0.0257 0.287 0.975
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0145 0.1483 0.8084
Echinococcus multilocularis jumonji domain containing protein 0.0049 0.0298 0.027
Schistosoma mansoni rab6-interacting 0.0048 0.0281 0.0281
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Schistosoma mansoni hypothetical protein 0.0041 0.0201 0.0201
Brugia malayi Bromodomain containing protein 0.0042 0.0216 0.0259
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.009 0.0161
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.013 0.0295
Onchocerca volvulus 0.0048 0.0281 0.0738
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Entamoeba histolytica hypothetical protein 0.0043 0.0229 0.0468
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0035 0.0127 0.0127
Brugia malayi 6-phosphofructokinase 0.0131 0.1315 0.1936
Schistosoma mansoni bromodomain containing protein 0.0081 0.069 0.069
Schistosoma mansoni microtubule-associated protein tau 0.0833 1 1
Entamoeba histolytica mannose-6-phosphate isomerase, putative 0.0054 0.0357 0.0786
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0047 0.0277 0.025
Leishmania major 4-coumarate:coa ligase-like protein 0.0029 0.0046 0.0017
Echinococcus granulosus caspase 0.012 0.1175 0.1149
Loa Loa (eye worm) doublecortin family protein 0.0048 0.0281 0.0744
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0052 0.0334 0.1644
Trypanosoma brucei metacaspase MCA2 0.0032 0.0088 0.0163
Loa Loa (eye worm) glucose-6-phosphate dehydrogenase 0.0263 0.2942 0.7793
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Loa Loa (eye worm) jmjC domain-containing protein 0.0073 0.0591 0.1565
Leishmania major glucose-6-phosphate 1-dehydrogenase, putative 0.0263 0.2942 1
Echinococcus granulosus hexokinase 0.0096 0.0882 0.0855
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.013 0.0222
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trypanosoma cruzi hexokinase, putative 0.0096 0.0882 0.2856
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Schistosoma mansoni lipoxygenase 0.0123 0.1218 0.1218
Plasmodium falciparum metacaspase 1 0.0032 0.0088 0.0156
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.0678 0.0678
Schistosoma mansoni zinc finger protein 0.0028 0.0037 0.0037
Echinococcus granulosus geminin 0.0205 0.2223 0.2201
Brugia malayi Hexokinase family protein 0.003 0.006 0.0021
Trypanosoma cruzi heat shock protein 85, putative 0.0047 0.0277 0.0761
Loa Loa (eye worm) hypothetical protein 0.006 0.0438 0.1161
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.013 0.0182
Trypanosoma brucei Metacaspase-4 0.0032 0.0088 0.0163
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0052 0.0334 0.101
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.1315 0.1315
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0172 0.1825 0.4776
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0376 0.1155
Brugia malayi Doublecortin family protein 0.0048 0.0281 0.0358
Plasmodium vivax hypothetical protein, conserved 0.0035 0.0127 0.0285
Onchocerca volvulus 0.0096 0.0882 0.2624
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Entamoeba histolytica hypothetical protein 0.0043 0.0229 0.0468
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0013
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0263 0.2942 0.7769
Brugia malayi Calcitonin receptor-like protein seb-1 0.006 0.0436 0.0596
Onchocerca volvulus Serine\/threonine kinase homolog 0.0114 0.1103 0.3319
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0172 0.1825 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0032 0.0088 0.0088
Toxoplasma gondii NAC domain-containing protein 0.0042 0.0214 0.0572
Loa Loa (eye worm) phosphofructokinase 0.0131 0.1315 0.3485
Echinococcus granulosus endoplasmin 0.0052 0.0334 0.0307
Leishmania major heat shock protein, putative 0.0037 0.0147 0.0363
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0353 0.4058 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Mycobacterium tuberculosis Conserved protein 0.003 0.0058 0.0093
Loa Loa (eye worm) hypothetical protein 0.0085 0.0748 0.1982
Plasmodium vivax SET domain protein, putative 0.0036 0.0138 0.0319
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0114 0.1103 0.366
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0046 0.0013
Brugia malayi Thioredoxin reductase 0.0057 0.0398 0.0537
Plasmodium falciparum thioredoxin reductase 0.0057 0.0398 0.118
Onchocerca volvulus 0.0048 0.0281 0.0738
Entamoeba histolytica acyl-coA synthetase, putative 0.0029 0.0046 0.0012
Leishmania major metacaspase, putative 0.0032 0.0088 0.0163
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0376 0.1104
Loa Loa (eye worm) hypothetical protein 0.0066 0.0503 0.1333
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.1315 0.1315
Brugia malayi Hexokinase family protein 0.006 0.0438 0.0598
Entamoeba histolytica hypothetical protein 0.0043 0.0229 0.0468
Brugia malayi Bromodomain containing protein 0.0051 0.0317 0.0413
Schistosoma mansoni endoplasmin 0.0055 0.0376 0.0376
Trypanosoma cruzi heat shock protein 85, putative 0.0055 0.0376 0.1104
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.1315 0.3173
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0088 0.0076
Entamoeba histolytica transcription factor BTF3, putative 0.0042 0.0214 0.0431
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0076 0.0637 0.061
Trypanosoma brucei metacaspase 5, putative 0.0032 0.0088 0.0163
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0825 0.0825
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1315 0.3144
Mycobacterium ulcerans hypothetical protein 0.003 0.0058 0.0045
Entamoeba histolytica acetyltransferase, GNAT family 0.0047 0.0275 0.0583
Mycobacterium tuberculosis Probable oxidoreductase 0.0145 0.1483 0.8084
Brugia malayi hypothetical protein 0.0182 0.1949 0.2902
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Echinococcus multilocularis caspase 8 0.0032 0.0088 0.006
Entamoeba histolytica heat shock protein 90, putative 0.0055 0.0376 0.0834
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0229 0.0201
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Schistosoma mansoni polycystin 1-related 0.0048 0.0281 0.0281
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trypanosoma brucei phosphomannose isomerase 0.0117 0.1144 0.3803
Onchocerca volvulus Cell death protein 3 homolog 0.0032 0.0088 0.0133
Echinococcus granulosus thioredoxin glutathione reductase 0.0057 0.0398 0.0371
Plasmodium vivax heat shock protein 90, putative 0.0037 0.0147 0.0348
Loa Loa (eye worm) glutathione reductase 0.0057 0.0398 0.1055
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.1315 0.3173
Loa Loa (eye worm) acetyltransferase 0.0178 0.1892 0.5012
Echinococcus multilocularis lipoxygenase domain containing protein 0.0048 0.0281 0.0253
Echinococcus granulosus glucose 6 phosphate 1 dehydrogenase 0.0263 0.2942 0.2922
Brugia malayi phosphofructokinase 0.0131 0.1315 0.1936
Brugia malayi glutathione reductase 0.0057 0.0398 0.0537
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.0678 0.0964
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.1315 0.3144
Schistosoma mansoni endoplasmin 0.0055 0.0376 0.0376
Trypanosoma cruzi Putative Phosphatase/Protein of unknown function DUF89, putative 0.0066 0.0505 0.155
Echinococcus multilocularis peregrin 0.0042 0.0216 0.0188
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0214 0.0391
Trypanosoma cruzi polo-like protein kinase, putative 0.0114 0.1103 0.3623
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0046 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.1475 0.3907
Trichomonas vaginalis bromodomain-containing protein, putative 0.0054 0.0364 0.0765
Echinococcus multilocularis hexokinase type 2 0.0096 0.0882 0.0855
Mycobacterium ulcerans hypothetical protein 0.003 0.0058 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0088 0.0076
Echinococcus granulosus histone acetyltransferase KAT2B 0.017 0.1796 0.1773
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0247 0.0247
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.0678 0.2195
Onchocerca volvulus 0.0286 0.323 1
Trichomonas vaginalis heat shock protein, putative 0.0052 0.0334 0.0691
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.012 0.1175 0.1149
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.287 0.9749
Trypanosoma cruzi trypanothione reductase, putative 0.0057 0.0398 0.118
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0127 0.0285
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0678 0.215
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0029 0.0029
Mycobacterium ulcerans lipoprotein LpqF 0.0077 0.0643 0.1613
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.1315 0.7146
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Schistosoma mansoni hypothetical protein 0.0035 0.0127 0.0127
Echinococcus multilocularis mannose 6 phosphate isomerase 0.0117 0.1144 0.1119
Toxoplasma gondii PHD-finger domain-containing protein 0.0035 0.0127 0.0285
Brugia malayi hypothetical protein 0.0048 0.0281 0.0358
Trypanosoma brucei heat shock protein 84, putative 0.0037 0.0147 0.0363
Brugia malayi Endoplasmin precursor 0.0055 0.0376 0.0504
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.1315 0.4393
Trypanosoma cruzi transcription factor btf3, putative 0.0042 0.0214 0.0542
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.0678 0.0651
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0037 0.0147 0.0262
Brugia malayi GnHR receptor homolog 0.0559 0.6603 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0057 0.0392 0.0392
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0114 0.1103 0.1077
Trypanosoma cruzi hypothetical protein, conserved 0.0257 0.287 0.9749
Trypanosoma brucei heat shock protein 90, putative 0.0055 0.0376 0.1155
Echinococcus granulosus L aminoadipate semialdehyde 0.01 0.0934 0.0908
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.0678 0.215
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0115 0.1118 0.1093
Onchocerca volvulus 0.006 0.0438 0.1232
Echinococcus multilocularis heat shock protein 90 0.0055 0.0376 0.0349
Loa Loa (eye worm) hexokinase 0.0096 0.0882 0.2335
Loa Loa (eye worm) endoplasmin 0.0055 0.0376 0.0997
Trichomonas vaginalis heat shock protein, putative 0.0055 0.0376 0.0796
Onchocerca volvulus Hexokinase homolog 0.006 0.0438 0.1232
Plasmodium vivax endoplasmin, putative 0.0055 0.0376 0.1108
Echinococcus multilocularis microtubule associated protein 2 0.0833 1 1
Echinococcus granulosus caspase 3 0.0088 0.0778 0.0752
Schistosoma mansoni caspase-3 (C14 family) 0.012 0.1175 0.1175
Loa Loa (eye worm) pigment dispersing factor receptor c 0.006 0.0436 0.1156
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0046 0.0027
Brugia malayi hypothetical protein 0.0043 0.0229 0.0279
Schistosoma mansoni heat shock protein 0.0055 0.0376 0.0376
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.013 0.1303 0.7076
Schistosoma mansoni caspase-7 (C14 family) 0.012 0.1175 0.1175
Loa Loa (eye worm) heat shock protein 75 0.0037 0.0147 0.0388
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.013 0.0308
Trichomonas vaginalis 6-phosphogluconolactonase, putative 0.0273 0.3066 0.7521
Mycobacterium ulcerans heat shock protein 90 0.0052 0.0334 0.0785
Mycobacterium tuberculosis Probable mannose-6-phosphate isomerase ManA (phosphomannose isomerase) (phosphomannoisomerase) (PMI) (phosphohexoisomerase) (pho 0.0064 0.0479 0.2457
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0037 0.0147 0.0118
Mycobacterium tuberculosis Probable reductase 0.013 0.1303 0.7076
Echinococcus granulosus lipoxygenase domain containing protein 0.0048 0.0281 0.0253
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0172 0.1825 1
Brugia malayi jmjC domain containing protein 0.0045 0.0247 0.0307
Trichomonas vaginalis mannose-6-phosphate isomerase, putative 0.0117 0.1144 0.2716
Echinococcus granulosus hexokinase 0.0096 0.0882 0.0855
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0263 0.0235
Leishmania major trypanothione reductase 0.0057 0.0398 0.1231
Trichomonas vaginalis set domain proteins, putative 0.0286 0.323 0.7931
Brugia malayi PHD-finger family protein 0.0035 0.0127 0.0124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0127 0.0337
Toxoplasma gondii thioredoxin reductase 0.0057 0.0398 0.118
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0599 0.0572
Plasmodium falciparum hexokinase 0.0096 0.0882 0.2779
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.013 0.0295
Plasmodium vivax glucose-6-phosphate 1-dehydrogenase, putative 0.0273 0.3066 1
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.003 0.0058 0.0057
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.013 0.1303 0.7076
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Echinococcus multilocularis hexokinase 0.0096 0.0882 0.0855
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0043 0.0229 0.0201
Onchocerca volvulus 0.0096 0.0882 0.2624
Loa Loa (eye worm) hypothetical protein 0.0032 0.0088 0.0234
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0121 0.0093
Echinococcus multilocularis neuropeptide s receptor 0.0566 0.6697 0.6687
Echinococcus multilocularis hexokinase 0.0096 0.0882 0.0855
Leishmania major heat shock protein 83-1 0.0055 0.0376 0.1155
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0088 0.0076
Schistosoma mansoni hypothetical protein 0.0043 0.0229 0.0229
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.1315 0.1291
Loa Loa (eye worm) hexokinase 0.003 0.006 0.0159
Brugia malayi beta-NAC-like protein 0.0042 0.0214 0.0256
Trypanosoma brucei beta lactamase 0.0077 0.0643 0.2076
Brugia malayi mannose-6-phosphate isomerase, class I family protein 0.0117 0.1144 0.1675
Brugia malayi MH2 domain containing protein 0.0144 0.1475 0.218
Trypanosoma brucei trypanothione reductase 0.0057 0.0398 0.1231
Loa Loa (eye worm) hypothetical protein 0.0182 0.1949 0.5163
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.1475 0.3907
Plasmodium falciparum endoplasmin, putative 0.004 0.0189 0.0487
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.1315 0.3413
Echinococcus multilocularis L aminoadipate semialdehyde 0.01 0.0934 0.0908
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0036 0.0138 0.0138
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.016 0.1674 0.9157
Schistosoma mansoni serine/threonine protein kinase 0.0114 0.1103 0.1103
Giardia lamblia Fructose-bisphosphate aldolase 0.0353 0.4058 1
Onchocerca volvulus 0.0036 0.0138 0.0288
Schistosoma mansoni glutaminase 0.033 0.3775 0.3775
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0032 0.0088 0.0076
Trichomonas vaginalis CAMK family protein kinase 0.0114 0.1103 0.2613
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.013 0.0182
Loa Loa (eye worm) hexokinase type II 0.0096 0.0882 0.2335
Echinococcus multilocularis neuropeptide receptor A26 0.0566 0.6697 0.6687
Mycobacterium ulcerans glucose-6-phosphate 1-dehydrogenase 0.0172 0.1815 0.4749
Brugia malayi Pre-SET motif family protein 0.0251 0.2801 0.4201
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0353 0.4058 1
Trypanosoma cruzi hexokinase, putative 0.0096 0.0882 0.2856

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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