Detailed information for compound 225878

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 406.312 | Formula: C19H13F3N2O5
  • H donors: 2 H acceptors: 4 LogP: 4.68 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1ccc(c(c1)C(=O)O)/N=C/c1nc(oc1O)c1cccc(c1)OC(F)(F)F
  • InChi: 1S/C19H13F3N2O5/c1-10-5-6-14(13(7-10)17(25)26)23-9-15-18(27)28-16(24-15)11-3-2-4-12(8-11)29-19(20,21)22/h2-9,27H,1H3,(H,25,26)/b23-9+
  • InChiKey: APGHJUROXBTIIB-NUGSKGIGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Bacillus subtilis (strain 168) Holo-[acyl-carrieir-protein] synthase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Chlamydia trachomatis holo [acyl-carrier protein] synthase Get druggable targets OG5_130884 All targets in OG5_130884
Plasmodium knowlesi holo-[acyl-carrier-protein] synthase, putative Get druggable targets OG5_130884 All targets in OG5_130884
Mycobacterium leprae HOLO-[ACYL-CARRIER PROTEIN] SYNTHASE ACPS (HOLO-ACP SYNTHASE) (CoA:APO-[ACP]PANTETHEINEPHOSPHOTRANSFERASE) (CoA:APO-[ACYL-CARRIE Get druggable targets OG5_130884 All targets in OG5_130884
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative Get druggable targets OG5_130884 All targets in OG5_130884
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase Get druggable targets OG5_130884 All targets in OG5_130884
Candida albicans similar to holo-(acyl carrier protein) synthase Get druggable targets OG5_130884 All targets in OG5_130884
Candida albicans similar to holo-(acyl carrier protein) synthase Get druggable targets OG5_130884 All targets in OG5_130884
Plasmodium yoelii hypothetical protein Get druggable targets OG5_130884 All targets in OG5_130884
Plasmodium berghei holo-[acyl-carrier-protein] synthase, putative Get druggable targets OG5_130884 All targets in OG5_130884
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase Get druggable targets OG5_130884 All targets in OG5_130884
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative Get druggable targets OG5_130884 All targets in OG5_130884
Treponema pallidum 4'-phosphopantetheinyl transferase Get druggable targets OG5_130884 All targets in OG5_130884
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie Get druggable targets OG5_130884 All targets in OG5_130884
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Plasmodium vivax cloroquine resistance asscociatd protein Cg7, putative Holo-[acyl-carrieir-protein] synthase   121 aa 101 aa 25.7 %
Loa Loa (eye worm) reduced folate carrier family protein Holo-[acyl-carrieir-protein] synthase   121 aa 97 aa 24.7 %
Plasmodium vivax hypothetical protein, conserved Holo-[acyl-carrieir-protein] synthase   121 aa 106 aa 25.5 %
Trichomonas vaginalis conserved hypothetical protein Holo-[acyl-carrieir-protein] synthase   121 aa 117 aa 24.8 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii phosphofructokinase PFKII 0.001 0.0065 0.0206
Echinococcus multilocularis transcription factor Dp 1 0.0013 0.0118 0.0114
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0015 0.0141 0.0414
Mycobacterium tuberculosis Possible transcriptional regulatory protein 0.0036 0.0513 0.07
Echinococcus multilocularis inositol monophosphatase 1 0.0015 0.0142 0.0137
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0007 0.001 0.001
Treponema pallidum oxidoreductase 0.0015 0.0141 0.031
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0071 0.0083
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.02 0.3299 1
Entamoeba histolytica phosphofructokinase, putative 0.0038 0.0539 0.1623
Giardia lamblia Kinase, CMGC GSK 0.0041 0.0588 0.0839
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.1223 0.1749
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0217 0.0213
Schistosoma mansoni 6-phosphofructokinase 0.0038 0.0539 0.0539
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3026
Loa Loa (eye worm) thioredoxin reductase 0.016 0.2619 0.3631
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.016 0.2619 0.381
Brugia malayi RE15519p 0.0008 0.0032 0.0044
Brugia malayi Dopamine receptor protein 2 0.0008 0.0032 0.0044
Schistosoma mansoni dep domain containing protein 0.0007 0.0011 0.0011
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.528
Onchocerca volvulus 0.0008 0.0032 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0307 0.037
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.001 0.0013
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0016 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0028
Entamoeba histolytica recQ family helicase, putative 0.0044 0.0641 0.1932
Schistosoma mansoni Smad4 0.0008 0.0034 0.0034
Brugia malayi hypothetical protein 0.0009 0.004 0.0054
Schistosoma mansoni nuclear hormone receptor 0.0007 0.001 0.001
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0154 0.2521 0.9617
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0141 0.0137
Echinococcus multilocularis protein kinase shaggy 0.0041 0.0588 0.0584
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Mycobacterium ulcerans hypothetical protein 0.0015 0.0141 0.0156
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.001 0.0054 0.0063
Mycobacterium leprae HOLO-[ACYL-CARRIER PROTEIN] SYNTHASE ACPS (HOLO-ACP SYNTHASE) (CoA:APO-[ACP]PANTETHEINEPHOSPHOTRANSFERASE) (CoA:APO-[ACYL-CARRIE 0.0115 0.185 0.2674
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0347 0.0342
Brugia malayi G-protein coupled receptor 0.0008 0.0032 0.0044
Echinococcus granulosus protein kinase shaggy 0.0041 0.0588 0.0584
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0007 0.001 0.0013
Plasmodium vivax 6-phosphofructokinase, putative 0.001 0.0065 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0015 0.0141 0.015
Echinococcus granulosus ferritin 0.0009 0.004 0.0036
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0014 0.0132 0.0277
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0015 0.0141 0.031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0095
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0141 0.0168
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Mycobacterium ulcerans lipase LipD 0.0026 0.0326 0.0439
Giardia lamblia Purine nucleoside phosphorylase lateral transfer candidate 0.0391 0.6575 1
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.1223 0.4542
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.001 0.0006
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0032 0.0428 0.0573
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0141 0.0156
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.5227
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0062 0.0948 0.0944
Trichomonas vaginalis CAMK family protein kinase 0.0017 0.0178 0.0213
Loa Loa (eye worm) hypothetical protein 0.031 0.519 0.7203
Brugia malayi hypothetical protein 0.0052 0.0779 0.108
Schistosoma mansoni regulator of G protein signaling 0.0007 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Plasmodium falciparum glutathione reductase 0.016 0.2619 1
Toxoplasma gondii phosphorylase family protein 0.0081 0.1274 0.4843
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0007 0.001 0.0008
Echinococcus multilocularis regulator of G protein signaling 7 0.0014 0.0126 0.0122
Brugia malayi G-protein coupled receptor 0.0008 0.0032 0.0044
Schistosoma mansoni hypothetical protein 0.0173 0.2837 0.2837
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Loa Loa (eye worm) melatonin receptor type 1A 0.0008 0.0032 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0017 0.0179 0.046
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0095 0.0095
Brugia malayi hypothetical protein 0.0009 0.004 0.0054
Schistosoma mansoni hypothetical protein 0.0417 0.7004 0.7004
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0551 0.1912
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Trichomonas vaginalis penicillin-binding protein, putative 0.0026 0.0326 0.0393
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Schistosoma mansoni uridine phosphorylase 0.0081 0.1274 0.1274
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0081 0.1274 0.4742
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0032 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0544 0.1888
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0154 0.2521 0.9617
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0007 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.008 0.125 0.173
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0015 0.0141 0.0194
Echinococcus granulosus regulator of G protein signaling 7 0.0014 0.0126 0.0122
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0008 0.0032 0.0028
Toxoplasma gondii thioredoxin reductase 0.016 0.2619 1
Entamoeba histolytica protein kinase, putative 0.0041 0.0588 0.1771
Loa Loa (eye worm) programmed cell death 8 0.0015 0.0141 0.019
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Echinococcus multilocularis purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0141 0.031
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0551 0.0759
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Echinococcus multilocularis cyclin dependent kinase 1 0.0019 0.0209 0.0205
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0032
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0988 0.0988
Brugia malayi ecdysteroid receptor 0.0007 0.001 0.0013
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0015 0.0141 0.031
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0026 0.0326 0.0451
Echinococcus multilocularis FTZ F1 alpha 0.0007 0.001 0.0006
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3026
Onchocerca volvulus 0.0009 0.004 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.1274 0.1548
Schistosoma mansoni ap endonuclease 0.0019 0.0217 0.0217
Echinococcus multilocularis bloom syndrome protein 0.0064 0.0989 0.0986
Echinococcus multilocularis neuropeptide receptor A26 0.0008 0.0032 0.0028
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0055 0.0835 0.0831
Brugia malayi hypothetical protein 0.0124 0.2007 0.2785
Echinococcus granulosus nuclear factor of activated T cells 5 0.0075 0.1171 0.1167
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0141 0.0168
Trypanosoma cruzi DNA polymerase eta, putative 0.0059 0.0898 0.3271
Brugia malayi Dopamine receptor 0.0008 0.0032 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0948 0.0948
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0604 0.06
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0209 0.0209
Echinococcus granulosus expressed protein 0.0131 0.2119 0.2115
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0009 0.004 0.0054
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0081 0.1274 0.3854
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Brugia malayi CXXC zinc finger family protein 0.0029 0.0389 0.0539
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0032 0.0028
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0007 0.001 0.001
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0143 0.2332 0.8879
Brugia malayi DIX domain containing protein 0.0007 0.0011 0.0015
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0007 0.001 0.0013
Schistosoma mansoni ferritin light chain 0.0009 0.004 0.004
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.0045 0.0652 0.0938
Echinococcus granulosus 7tm_1 domain containing protein 0.0008 0.0032 0.0028
Onchocerca volvulus 0.0035 0.0495 0.059
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0007 0.001 0.001
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0142 0.0142
Onchocerca volvulus 0.0008 0.0032 0.0027
Echinococcus granulosus thioredoxin glutathione reductase 0.0161 0.2633 0.263
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0899 0.0895
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0015 0.0141 0.0156
Echinococcus multilocularis thioredoxin glutathione reductase 0.0161 0.2633 0.263
Mycobacterium ulcerans ferredoxin reductase 0.0015 0.0141 0.0156
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0141 0.0496
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0015 0.0142 0.0313
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0073 0.0043
Giardia lamblia Histone acetyltransferase GCN5 0.0013 0.0112 0.0112
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0041 0.0584 0.081
Onchocerca volvulus 0.0037 0.0516 0.0616
Loa Loa (eye worm) glutathione reductase 0.016 0.2619 0.3631
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0358 0.1161
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0041 0.0588 0.221
Echinococcus multilocularis lamin dm0 0.0055 0.0836 0.0832
Onchocerca volvulus 0.0488 0.8216 1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0018 0.0202 0.0279
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0038 0.0539 0.1866
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0122 0.0234
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0038 0.0539 0.0737
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0008 0.0032 0.0032
Entamoeba histolytica transcription factor BTF3, putative 0.0024 0.0307 0.0918
Onchocerca volvulus 0.0008 0.0032 0.0027
Onchocerca volvulus 0.0008 0.0032 0.0027
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0018 0.0202 0.0202
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0217 0.0261
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0012 0.0101 0.0097
Toxoplasma gondii ABC1 family protein 0.0026 0.0326 0.1206
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Echinococcus multilocularis cyclin dependent kinase 5 0.0019 0.0209 0.0205
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0019 0.0209 0.0285
Brugia malayi PXA domain containing protein 0.0007 0.0004 0.0005
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0021 0.024 0.028
Trichomonas vaginalis penicillin-binding protein, putative 0.0026 0.0326 0.0393
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Brugia malayi cell division control protein 2 homolog 0.0019 0.0209 0.0289
Schistosoma mansoni jumonji domain containing protein 0.0011 0.0073 0.0073
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0121 0.1949 0.738
Echinococcus multilocularis serotonin receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0009 0.004 0.0049
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0023 0.0284 0.0849
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0143 0.2332 0.3508
Trypanosoma cruzi transcription factor btf3, putative 0.0024 0.0307 0.0959
Loa Loa (eye worm) 6-phosphofructokinase 0.0038 0.0539 0.0742
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0018 0.0197 0.0268
Brugia malayi hypothetical protein 0.0007 0.0004 0.0005
Schistosoma mansoni z-protein (S1r protein) 0.0014 0.0126 0.0126
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0095
Entamoeba histolytica acetyltransferase, GNAT family 0.0013 0.0112 0.0328
Brugia malayi jmjC domain containing protein 0.0011 0.0073 0.01
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0026 0.0326 0.0447
Echinococcus granulosus survival motor neuron protein 1 0.0241 0.4003 0.4
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Schistosoma mansoni dihydrofolate reductase 0.0045 0.0652 0.0652
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0007 0.001 0.0008
Schistosoma mansoni regulator of G protein signaling 0.0014 0.0126 0.0126
Schistosoma mansoni myoglobin 1 0.0009 0.004 0.004
Brugia malayi jmjC domain containing protein 0.0042 0.0604 0.0838
Schistosoma mansoni ferritin 0.0009 0.004 0.004
Onchocerca volvulus 0.0007 0.0011 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0008 0.0032 0.0044
Brugia malayi Rhodanese-like domain containing protein 0.001 0.0054 0.0075
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.011 0.0105
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0039 0.055 0.0762
Trichomonas vaginalis inositol monophosphatase, putative 0.0015 0.0142 0.0169
Entamoeba histolytica recQ family DNA helicase 0.002 0.0226 0.0674
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Trypanosoma cruzi cdc2-related kinase 1 0.0019 0.0209 0.0577
Brugia malayi Globin family protein 0.0009 0.004 0.0054
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0015 0.0141 0.0149
Brugia malayi Serotonin receptor 0.0008 0.0032 0.0044
Onchocerca volvulus 0.0008 0.0032 0.0027
Plasmodium vivax protein kinase Crk2 0.0019 0.0209 0.0577
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0041 0.0584 0.081
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0141 0.0141
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0015 0.0141 0.0149
Echinococcus granulosus single minded 2 0.0037 0.0516 0.0512
Mycobacterium ulcerans hypothetical protein 0.0021 0.024 0.0308
Plasmodium falciparum basic transcription factor 3b, putative 0.0024 0.0307 0.0959
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0041 0.0598 0.0594
Plasmodium falciparum ferrodoxin reductase-like protein 0.0015 0.0141 0.031
Leishmania major NADH dehydrogenase, putative 0.0015 0.0141 0.0392
Brugia malayi G protein-coupled receptor 0.0008 0.0032 0.0044
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0141 0.031
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0015 0.0142 0.0313
Onchocerca volvulus 0.0029 0.0389 0.0462
Loa Loa (eye worm) DIX domain-containing protein 0.0007 0.0011 0.001
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.001 0.0054 0.0063
Toxoplasma gondii NAC domain-containing protein 0.0024 0.0307 0.1133
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Echinococcus granulosus neuropeptides capa receptor 0.0008 0.0032 0.0028
Onchocerca volvulus 0.0009 0.004 0.0036
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0017 0.0179 0.046
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.001 0.0054 0.0054
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.001
Toxoplasma gondii aldehyde dehydrogenase 0.0041 0.0598 0.225
Mycobacterium tuberculosis Possible nitrate/nitrite response transcriptional regulatory protein NarL 0.0036 0.0513 0.07
Echinococcus granulosus dihydrofolate reductase 0.0045 0.0652 0.0648
Schistosoma mansoni DNA helicase recq5 0.0039 0.055 0.055
Brugia malayi Globin family protein 0.0009 0.004 0.0054
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0073 0.0095
Echinococcus multilocularis lysine specific demethylase 5A 0.004 0.0576 0.0572
Schistosoma mansoni phd/f-box containing protein 0.0011 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Brugia malayi Thioredoxin reductase 0.016 0.2619 0.3634
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.008 0.125 0.1246
Onchocerca volvulus 0.0009 0.004 0.0036
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0015 0.0141 0.0168
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0039 0.055 0.0546
Schistosoma mansoni apoferritin-2 0.0009 0.004 0.004
Trypanosoma cruzi NADH dehydrogenase, putative 0.0015 0.0141 0.031
Echinococcus multilocularis purine nucleoside phosphorylase 0.031 0.519 0.5188
Echinococcus granulosus somatostatin receptor 0.0008 0.0032 0.0028
Trichomonas vaginalis DNA helicase recq, putative 0.0044 0.0641 0.0777
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Echinococcus multilocularis G-protein coupled receptor, putative 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0326 0.0447
Trichomonas vaginalis conserved hypothetical protein 0.0008 0.0019 0.0019
Schistosoma mansoni purine nucleoside phosphorylase 0.0391 0.6575 0.6575
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0015 0.0142 0.0444
Loa Loa (eye worm) hypothetical protein 0.0026 0.0326 0.0447
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0049 0.0729 0.1011
Brugia malayi hypothetical protein 0.0007 0.0011 0.0015
Brugia malayi larval opioid receptor 0.0008 0.0032 0.0044
Echinococcus granulosus Ankyrin 0.0015 0.0142 0.0138
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0015 0.0141 0.0414
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0397 0.055
Trichomonas vaginalis ferritin, putative 0.0009 0.004 0.0045
Plasmodium falciparum glutathione reductase 0.0055 0.0835 0.3026
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.001 0.0065 0.004
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0018 0.0202 0.0274
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0346 0.111
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0544 0.0544
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0032 0.0028
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0021 0.024 0.0308
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0604 0.0604
Echinococcus multilocularis serotonin receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) globin family protein 0.0009 0.004 0.0049
Schistosoma mansoni lamin 0.0055 0.0836 0.0836
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0365 0.6114 0.8974
Brugia malayi MH1 domain containing protein 0.0008 0.0034 0.0046
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0007 0.0004 0.0002
Brugia malayi Dihydrofolate reductase 0.0045 0.0652 0.0904
Schistosoma mansoni single-minded 0.005 0.0736 0.0736
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0007 0.001 0.001
Trypanosoma cruzi trypanothione reductase, putative 0.016 0.2619 1
Echinococcus granulosus allatostatin A receptor 0.0008 0.0032 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0007 0.001 0.0013
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0544 0.0773
Onchocerca volvulus 0.0049 0.0729 0.0875
Giardia lamblia DINP protein human, muc B family 0.0039 0.0551 0.0783
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0023 0.0284 0.0388
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.011 0.013
Brugia malayi polk-prov protein 0.0012 0.0095 0.0131
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0028
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0544 0.0659
Echinococcus multilocularis expressed protein 0.0131 0.2119 0.2115
Loa Loa (eye worm) hypothetical protein 0.001 0.0062 0.008
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0081 0.1274 0.4742
Mycobacterium tuberculosis Conserved hypothetical protein 0.0081 0.1274 0.1824
Echinococcus granulosus dna polymerase kappa 0.0039 0.0551 0.0547
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0019 0.0209 0.0285
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0043 0.0629 0.0629
Trichomonas vaginalis DNA helicase recq1, putative 0.0064 0.0989 0.1201
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Mycobacterium ulcerans glutaminase 0.0205 0.3386 0.5121
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0009 0.0039 0.0044
Trichomonas vaginalis apoptosis inducing factor, putative 0.0015 0.0141 0.0168
Mycobacterium ulcerans two component transcriptional regulatory protein DevR 0.0036 0.0513 0.0725
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0405 0.6809 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.011 0.0146
Brugia malayi PAS domain containing protein 0.005 0.0736 0.1021
Schistosoma mansoni growth hormone secretagogue receptor 0.0008 0.0032 0.0032
Echinococcus granulosus beta LACTamase domain containing family member 0.0026 0.0326 0.0322
Plasmodium falciparum histone acetyltransferase GCN5 0.0013 0.0112 0.0198
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0015 0.0142 0.0169
Onchocerca volvulus Serine\/threonine kinase homolog 0.0034 0.0462 0.0551
Schistosoma mansoni smad1 5 8 and 0.0008 0.0034 0.0034
Schistosoma mansoni purine nucleoside phosphorylase 0.0391 0.6575 0.6575
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.014 0.0136
Echinococcus multilocularis thyroid hormone receptor alpha 0.0007 0.001 0.0006
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0013 0.0115 0.0112
Entamoeba histolytica hypothetical protein 0.0028 0.0372 0.1116
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0065 0.0076
Loa Loa (eye worm) RecQ helicase 0.0064 0.0989 0.1368
Loa Loa (eye worm) hypothetical protein 0.0027 0.0347 0.0475
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0141 0.0168
Loa Loa (eye worm) hypothetical protein 0.0015 0.014 0.0188
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0012 0.0095 0.032
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Trypanosoma brucei transcription factor BTF3, putative 0.0024 0.0307 0.0959
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0055 0.0835 0.1218
Giardia lamblia DNA damage repair protein 0.0012 0.0095 0.0085
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0023 0.0284 0.087
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0217 0.03
Trypanosoma brucei trypanothione reductase 0.016 0.2619 1
Plasmodium vivax SET domain protein, putative 0.0062 0.0948 0.3468
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0015 0.0151 0.0204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0007 0.001 0.0008
Echinococcus multilocularis 6 phosphofructokinase 0.0038 0.0539 0.0535
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Loa Loa (eye worm) acetyltransferase 0.0048 0.0715 0.0987
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0081 0.1274 0.3854
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0544 0.054
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0007 0.001 0.0008
Trypanosoma brucei methylthioadenosine phosphorylase, putative 0.0081 0.1274 0.4742
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0043 0.0629 0.0625
Mycobacterium tuberculosis Probable hydrolase 0.0026 0.0326 0.0424
Onchocerca volvulus 0.0026 0.0326 0.0384
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.055 0.2065
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0008 0.0032 0.0028
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0032 0.0032
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0063 0.0969 0.0969
Plasmodium falciparum purine nucleoside phosphorylase 0.0081 0.1274 0.4742
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0365 0.6114 0.8974
Brugia malayi Cytochrome P450 family protein 0.0009 0.004 0.0054
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0544 0.054
Mycobacterium tuberculosis Conserved protein 0.0026 0.0326 0.0424
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0598 0.0855
Loa Loa (eye worm) hypothetical protein 0.0015 0.0151 0.0204
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0009 0.004 0.0001
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.014 0.0193
Loa Loa (eye worm) cytochrome P450 family protein 0.0009 0.004 0.0049
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0039 0.055 0.1909
Trypanosoma brucei chrX additional, unordered contigs 0.0012 0.0095 0.013
Schistosoma mansoni ferritin 0.0009 0.004 0.004
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.011 0.0105
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0009 0.0039 0.0035
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0008 0.0032 0.0028
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.001 0.0054 0.0063
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0028
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.024 0.0297
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0516 0.073
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0043 0.0629 0.0872
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Trichomonas vaginalis set domain proteins, putative 0.0487 0.8214 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0019 0.0213 0.0593
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0007 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Brugia malayi follicle stimulating hormone receptor 0.0247 0.4104 0.5696
Mycobacterium ulcerans hypothetical protein 0.0012 0.0095 0.0085
Mycobacterium leprae Possible regulatory protein 0.0013 0.011 0.0103
Mycobacterium tuberculosis Probable esterase LipL 0.0026 0.0326 0.0424
Treponema pallidum thioredoxin reductase (trxB) 0.0015 0.0141 0.031
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0008 0.0032 0.0044
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0544 0.054
Mycobacterium ulcerans 6-phosphofructokinase 0.0038 0.0539 0.0765
Echinococcus granulosus methylthioadenosine phosphorylase 0.0081 0.1274 0.127
Schistosoma mansoni thyroid hormone receptor 0.0007 0.001 0.001
Onchocerca volvulus 0.0015 0.0141 0.0159
Echinococcus multilocularis dna polymerase eta 0.0059 0.0898 0.0894
Trypanosoma brucei hypothetical protein, conserved 0.0028 0.0372 0.1214
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0095 0.013
Brugia malayi nuclear receptor NHR-88 0.0007 0.001 0.0013
Mycobacterium tuberculosis Hypothetical protein 0.0052 0.0779 0.1093
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0021 0.024 0.0333
Brugia malayi 6-phosphofructokinase 0.0038 0.0539 0.0747
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Plasmodium vivax glycogen synthase kinase 3, putative 0.0041 0.0588 0.2057
Onchocerca volvulus 0.0009 0.004 0.0036
Echinococcus granulosus sex peptide receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0008 0.0032 0.0039
Echinococcus granulosus neuropeptide receptor A26 0.0008 0.0032 0.0028
Entamoeba histolytica disulphide oxidoreductase, putative 0.0015 0.0141 0.0414
Echinococcus multilocularis survival motor neuron protein 1 0.0241 0.4003 0.4
Giardia lamblia Kinase, PLK 0.0034 0.0462 0.0648
Entamoeba histolytica phosphofructokinase, putative 0.0038 0.0539 0.1623
Echinococcus multilocularis ferritin 0.0009 0.004 0.0036
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0122 0.0234
Schistosoma mansoni glutamate synthase 0.0015 0.0141 0.0141
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0015 0.0141 0.0156
Leishmania major hypothetical protein, conserved 0.0015 0.0141 0.0392
Echinococcus granulosus bloom syndrome protein 0.0064 0.0989 0.0986
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0641 0.2265
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0141 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0004 0.0002
Brugia malayi jmjC domain containing protein 0.0011 0.0073 0.01
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Onchocerca volvulus 0.0028 0.0372 0.0441
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Echinococcus granulosus cyclin dependent kinase 5 0.0019 0.0209 0.0205
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0141 0.0168
Schistosoma mansoni adenoreceptor 0.0008 0.0032 0.0032
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0041 0.0588 0.2124
Onchocerca volvulus 0.0008 0.0032 0.0027
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0015 0.0141 0.0156
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0009 0.004 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.001 0.0006
Brugia malayi hypothetical protein 0.0036 0.0497 0.0688
Echinococcus multilocularis allatostatin A receptor 0.0008 0.0032 0.0028
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0513 0.0725
Plasmodium vivax DNA repair protein REV1, putative 0.0012 0.0095 0.013
Brugia malayi 6-phosphofructokinase 0.0038 0.0539 0.0747
Echinococcus multilocularis methylthioadenosine phosphorylase 0.0081 0.1274 0.127
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Trypanosoma brucei unspecified product 0.0039 0.0551 0.1912
Giardia lamblia Kinase, CMGC GSK 0.0041 0.0588 0.0839
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0028 0.0372 0.0515
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0052 0.0052
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0008 0.0032 0.0032
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0217 0.0607
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.1223 0.4542
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0015 0.0141 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0071 0.0083
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0032 0.0032
Schistosoma mansoni DNA helicase recq1 0.0039 0.055 0.055
Mycobacterium tuberculosis Probable thymidylate synthase ThyA (ts) (TSASE) 0.0109 0.1759 0.254
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0143 0.2332 0.8879
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0141 0.0194
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0641 0.2265
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0063 0.0969 0.0965
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Trichomonas vaginalis CMGC family protein kinase 0.0019 0.0209 0.0251
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0026 0.0326 0.0424
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0007 0.001 0.0006
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0023 0.0284 0.0947
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.011 0.013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0095 0.013
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Leishmania major DNA damage repair protein, putative 0.0012 0.0095 0.0214
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Schistosoma mansoni axis inhibition protein axin 0.0007 0.0004 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0217 0.0261
Onchocerca volvulus 0.0008 0.0032 0.0027
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0028
Echinococcus granulosus serotonin receptor 0.0008 0.0032 0.0028
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0062 0.0948 0.3594
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0014 0.0126 0.0169
Brugia malayi GnHR receptor homolog 0.0008 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0007 0.001 0.0008
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0081 0.1274 0.3854
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0017 0.0179 0.046
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0052 0.0048
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0065 0.0076
Brugia malayi Tachykinin-like peptides receptor 99D 0.0008 0.0032 0.0044
Entamoeba histolytica phosphofructokinase, putative 0.0038 0.0539 0.1623
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Mycobacterium tuberculosis Possible two component transcriptional regulatory protein (probably LuxR-family) 0.0036 0.0513 0.07
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Echinococcus granulosus ecdysone induced protein 78C 0.0007 0.001 0.0006
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0217 0.0645
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.011 0.013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0032 0.0028
Leishmania major basic transcription factor 3a, putative 0.0024 0.0307 0.1035
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3026
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Onchocerca volvulus 0.0008 0.0032 0.0027
Echinococcus multilocularis segment polarity protein dishevelled 0.0007 0.0011 0.0007
Onchocerca volvulus Purine nucleoside phosphorylase homolog 0.0391 0.6575 0.8
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0781 0.1096
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase, putative 0.0052 0.0779 0.2805
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0163 0.2675 0.3894
Plasmodium vivax JmjC domain containing protein 0.0011 0.0073 0.0043
Leishmania major mitochondrial DNA polymerase beta 0.0121 0.1949 0.7402
Schistosoma mansoni biogenic amine receptor 0.0008 0.0032 0.0032
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0836 0.116
Trichomonas vaginalis conserved hypothetical protein 0.0081 0.1274 0.1548
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0081 0.1274 0.189
Echinococcus granulosus uridine phosphorylase 1 0.0081 0.1274 0.127
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0032 0.0039
Mycobacterium ulcerans monoxygenase 0.0015 0.0141 0.0156
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0023 0.0284 0.0393
Loa Loa (eye worm) hypothetical protein 0.0009 0.004 0.0049
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0014 0.0132 0.0464
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0083 0.0079
Trypanosoma brucei cdc2-related kinase 3 0.0019 0.0209 0.0577
Trichomonas vaginalis cdc25b, putative 0.001 0.0054 0.0063
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0028
Onchocerca volvulus 0.0008 0.0032 0.0027
Chlamydia trachomatis thioredoxin reductase 0.0015 0.0141 0.0334
Mycobacterium ulcerans purine nucleoside phosphorylase 0.0391 0.6575 1
Echinococcus granulosus m phase inducer phosphatasecdc25 0.001 0.0054 0.005
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0358 0.0471
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0008 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni glutamate synthase 0.0015 0.0141 0.0141
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0055 0.0835 0.0831
Brugia malayi hypothetical protein 0.0009 0.004 0.0054
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.008 0.125 0.1788
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0141 0.031
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0098 0.1555 0.232
Loa Loa (eye worm) steroid hormone receptor 0.0007 0.001 0.0008
Trichomonas vaginalis CMGC family protein kinase 0.0019 0.0209 0.0251
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0836 0.1155
Brugia malayi Serotonin receptor 0.0008 0.0032 0.0044
Plasmodium vivax glutathione reductase, putative 0.016 0.2619 1
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0143 0.2332 0.7033
Onchocerca volvulus Neuropeptide F receptor homolog 0.0008 0.0032 0.0027
Echinococcus granulosus expressed protein 0.0009 0.004 0.0036
Brugia malayi latrophilin 2 splice variant baaae 0.001 0.0069 0.0094
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0055 0.0835 0.3085
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0011 0.0073 0.0235
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0081 0.1274 0.4742
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0141 0.0168
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0015 0.0141 0.0156
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0018 0.0202 0.0197
Mycobacterium ulcerans dehydrogenase 0.0015 0.0141 0.0156
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0083 0.0109
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0154 0.2521 0.9617
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0098 0.1555 0.2239
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.004 0.0576 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0095 0.013
Leishmania major protein kinase, putative 0.0014 0.0122 0.0317
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni netrin receptor unc5 0.0015 0.014 0.014
Echinococcus granulosus inositol monophosphatase 1 0.0015 0.0142 0.0137
Brugia malayi jmjC domain containing protein 0.0011 0.0073 0.01
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0095 0.013
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.001 0.0065 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.0038 0.0539 0.0653
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0012 0.0101 0.0097
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0014 0.0132 0.0464
Loa Loa (eye worm) inositol-1 0.0015 0.0142 0.0191
Echinococcus granulosus beta-adrenergic receptor kinase 0.0007 0.0016 0.0012
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0015 0.0141 0.0392
Loa Loa (eye worm) hypothetical protein 0.0323 0.5408 0.7504
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0068 0.1057 0.1503
Echinococcus granulosus geminin 0.0173 0.2837 0.2834
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Echinococcus multilocularis G protein coupled receptor 139 0.0008 0.0032 0.0028
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.014 0.0136
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Giardia lamblia Glutamate synthase 0.0015 0.0141 0.0156
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0015 0.0141 0.0496
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0057 0.0864 0.3139
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.011 0.0105
Trypanosoma brucei DNA damage repair protein, putative 0.0012 0.0095 0.013
Brugia malayi Inositol-1 0.0015 0.0142 0.0196
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0028
Echinococcus granulosus inosine guanosine and xanthosine phosphorylase 0.031 0.519 0.5188
Mycobacterium leprae probable uridine phosphorylase 0.0081 0.1274 0.1823
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0007 0.001 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0028
Echinococcus granulosus segment polarity protein dishevelled 0.0007 0.0011 0.0007
Loa Loa (eye worm) beta-lactamase 0.0026 0.0326 0.0447
Echinococcus granulosus dnaJ subfamily B 0.0417 0.7004 0.7003
Mycobacterium tuberculosis Probable transcriptional regulatory protein (LuxR-family) 0.0036 0.0513 0.07
Treponema pallidum NADH oxidase 0.0055 0.0835 0.2441
Brugia malayi nuclear hormone receptor 0.0007 0.001 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0032 0.0028
Schistosoma mansoni lamin 0.0055 0.0836 0.0836
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Leishmania major hypothetical protein, conserved 0.001 0.0062 0.0085
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0041 0.0598 0.0594
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0122 0.0234
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0052 0.0779 0.0945
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0007 0.001 0.0013
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0007 0.001 0.0006
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.1057 0.1053
Loa Loa (eye worm) hypothetical protein 0.0009 0.004 0.0049
Onchocerca volvulus 0.0055 0.0836 0.1006
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0015 0.0141 0.0149
Trichomonas vaginalis CAMK family protein kinase 0.0017 0.0178 0.0213
Echinococcus granulosus dro:myosuppressin receptor 0.0008 0.0032 0.0028
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0145 0.2361 0.2865
Echinococcus multilocularis JmjC domain containing protein 4 0.0011 0.0073 0.0068
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0551 0.0547
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0358 0.1161
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0034 0.0462 0.0458
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0013 0.011 0.0197
Trypanosoma brucei hypothetical protein, conserved 0.0012 0.0095 0.013
Echinococcus granulosus cyclin dependent kinase 5 activator 1 0.0108 0.1734 0.1731
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0598 0.0855
Schistosoma mansoni phosphatidylserine receptor 0.0011 0.0073 0.0073
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0007 0.0004 0.0004
Brugia malayi Smad1 0.0008 0.0034 0.0046
Plasmodium vivax basic transcription factor 3b, putative 0.0024 0.0307 0.0959
Giardia lamblia Sgs1 DNA helicase, putative 0.0039 0.055 0.0781
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0019 0.0209 0.0205
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0397 0.0545
Brugia malayi intermediate filament protein 0.0055 0.0836 0.116
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0007 0.001 0.0006
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Loa Loa (eye worm) dihydrofolate reductase 0.0045 0.0652 0.0899
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0551 0.0667
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.001 0.0054 0.0063
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0008 0.0032 0.0032
Echinococcus multilocularis Ankyrin 0.0015 0.0142 0.0138
Brugia malayi Uncoordinated protein 44 0.0015 0.014 0.0193
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0028
Schistosoma mansoni ferritin light chain 0.0009 0.004 0.004
Trichomonas vaginalis glutaminase, putative 0.0205 0.3386 0.412
Loa Loa (eye worm) hypothetical protein 0.0009 0.004 0.0049
Mycobacterium ulcerans endonuclease IV 0.0078 0.1223 0.1811
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0015 0.0141 0.0392
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0032 0.0428 0.0574
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0015 0.0141 0.0414
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.008 0.125 0.4647
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0038 0.0539 0.1866
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0015 0.0141 0.0137
Entamoeba histolytica protein kinase domain containing protein 0.0041 0.0588 0.1771
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0141 0.031
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.014 0.0136
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.011 0.013
Entamoeba histolytica rodhanase-like domain containing protein 0.001 0.0054 0.0152
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0034 0.003
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0015 0.0141 0.0496
Entamoeba histolytica cell division protein kinase 2, putative 0.0019 0.0209 0.0622
Brugia malayi Bloom's syndrome protein homolog 0.0064 0.0989 0.1372
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0055 0.0835 0.3026
Schistosoma mansoni protein phosphatase 2C 0.0011 0.0073 0.0073
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0217 0.0772
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0008 0.0032 0.0028
Schistosoma mansoni DNA polymerase eta 0.0059 0.0898 0.0898
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0032 0.0032
Brugia malayi neuropeptide F receptor 0.0008 0.0032 0.0044
Brugia malayi putative neuropeptide receptor NPR1 0.0008 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0372 0.0511
Echinococcus granulosus tachykinin peptides receptor 99D 0.0008 0.0032 0.0028
Echinococcus granulosus neuropeptide Y receptor 0.0008 0.0032 0.0028
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.1057 0.1557
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0588 0.0712
Mycobacterium ulcerans bacterioferritin BfrA 0.0009 0.004 0.0001
Echinococcus multilocularis cyclin dependent kinase 1 0.0019 0.0209 0.0205
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis cyclin dependent kinase 0.0019 0.0209 0.0205
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0068 0.1057 0.1557
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0008 0.0032 0.0032
Schistosoma mansoni smad1 5 8 and 0.0008 0.0034 0.0034
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0055 0.0835 0.3026
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0026 0.0326 0.0326
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0066 0.1016 0.1016
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0015 0.0141 0.031
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni hypothetical protein 0.0015 0.014 0.014
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0015 0.0151 0.0209
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.001 0.0065 0.0185
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0031 0.0426 0.0426
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0018 0.0202 0.0197
Echinococcus granulosus FTZ F1 alpha 0.0007 0.001 0.0006
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.011 0.013
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Onchocerca volvulus 0.0109 0.1759 0.2131
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Mycobacterium ulcerans glutamate synthase subunit beta 0.0015 0.0141 0.0156
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0095 0.013
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0011 0.0073 0.0043
Onchocerca volvulus 0.001 0.0054 0.0054
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Brugia malayi Pre-SET motif family protein 0.0428 0.7205 1
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0365 0.6114 0.8974
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0026 0.0326 0.0424
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0604 0.0604
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0141 0.0149
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0008 0.0032 0.0039
Toxoplasma gondii endonuclease IV APN 0.0078 0.1223 0.4647
Toxoplasma gondii NADPH-glutathione reductase 0.0055 0.0835 0.316
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0071 0.0083
Trypanosoma cruzi polo-like protein kinase, putative 0.0034 0.0462 0.1567
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0226 0.0643
Schistosoma mansoni opsin-like receptor 0.0008 0.0032 0.0032
Leishmania major DNA polymerase eta, putative 0.0059 0.0898 0.3328
Schistosoma mansoni hypothetical protein 0.001 0.0069 0.0069
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0015 0.0141 0.031
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Brugia malayi phosphofructokinase 0.0038 0.0539 0.0747
Schistosoma mansoni cpg binding protein 0.0029 0.0389 0.0389
Echinococcus granulosus tm gpcr rhodopsin 0.0008 0.0032 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0307 0.037
Leishmania major DNA polymerase eta, putative 0.0032 0.0442 0.156
Toxoplasma gondii hypothetical protein 0.0027 0.0358 0.1331
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0055 0.0835 0.3026
Trypanosoma cruzi DNA damage repair protein, putative 0.0012 0.0095 0.013
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0007 0.0011 0.0001
Mycobacterium leprae PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN 0.0036 0.0513 0.0699
Onchocerca volvulus 0.001 0.0054 0.0054
Brugia malayi dihydrofolate reductase family protein 0.0045 0.0652 0.0904
Brugia malayi glutaminase DH11.1 0.0205 0.3386 0.4699
Brugia malayi ORL1-like opioid receptor 0.0008 0.0032 0.0044
Trichomonas vaginalis D-aminoacylase, putative 0.0026 0.0326 0.0393
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Mycobacterium tuberculosis Hypothetical protein 0.0081 0.1274 0.1824
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Schistosoma mansoni dishevelled 0.0007 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0004 0.0002
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0141 0.031
Brugia malayi acetyltransferase, GNAT family protein 0.0048 0.0715 0.0991
Onchocerca volvulus 0.0035 0.0495 0.059
Brugia malayi SET domain containing protein 0.0007 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0326 0.0447
Trypanosoma cruzi methylthioadenosine phosphorylase, putative 0.0081 0.1274 0.4742
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0141 0.0168
Loa Loa (eye worm) hypothetical protein 0.0036 0.0497 0.0684
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.1223 0.1748
Loa Loa (eye worm) hypothetical protein 0.0009 0.004 0.0049
Schistosoma mansoni transcription factor btf3 0.0024 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis expressed protein 0.0009 0.004 0.0036
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0034 0.0034
Echinococcus multilocularis sex peptide receptor 0.0008 0.0032 0.0028
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0781 0.0777
Leishmania major hypothetical protein, conserved 0.0011 0.0073 0.0128
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0018 0.0202 0.0197
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0015 0.0142 0.0313
Brugia malayi hypothetical protein 0.0007 0.0011 0.0015
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0015 0.0142 0.0395
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0007 0.001 0.0006
Loa Loa (eye worm) hypothetical protein 0.0009 0.0039 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0071 0.0083
Echinococcus multilocularis geminin 0.0173 0.2837 0.2834
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0043 0.0629 0.0868
Onchocerca volvulus 0.0026 0.0326 0.0384
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0055 0.0835 0.3026
Echinococcus granulosus 6 phosphofructokinase 0.0038 0.0539 0.0535
Loa Loa (eye worm) hypothetical protein 0.0055 0.0836 0.1155
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0015 0.0141 0.0137
Mycobacterium tuberculosis Probable lipase LipE 0.0026 0.0326 0.0424
Brugia malayi hypothetical protein 0.0009 0.0039 0.0053
Echinococcus multilocularis regulator of G protein signaling 7 0.0014 0.0126 0.0122
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0007 0.0016 0.0016
Trypanosoma cruzi nucleoside phosphorylase, putative 0.0081 0.1274 0.4742
Loa Loa (eye worm) globin family protein 0.0009 0.004 0.0049
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0065 0.0076
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0015 0.0142 0.0169
Loa Loa (eye worm) hypothetical protein 0.0062 0.0948 0.1311
Brugia malayi Calcitonin receptor-like protein seb-1 0.0015 0.0151 0.0209
Echinococcus granulosus cyclin dependent kinase 1 0.0019 0.0209 0.0205
Plasmodium falciparum thioredoxin reductase 0.016 0.2619 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0365 0.6114 0.8974
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0015 0.0141 0.015
Giardia lamblia Fructose-bisphosphate aldolase 0.02 0.3299 0.4988
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0008 0.0032 0.0028
Trypanosoma brucei DNA polymerase eta, putative 0.0059 0.0898 0.3271
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0041 0.0588 0.081
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0008 0.0032 0.0028
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0347 0.0342
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0008 0.0032 0.0028
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0066 0.1011 0.1486
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0055 0.0835 0.0835
Brugia malayi glutathione reductase 0.016 0.2619 0.3634
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0217 0.0213
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.1223 0.1697
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0008 0.0032 0.0028
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0026 0.0326 0.0424
Schistosoma mansoni blooms syndrome DNA helicase 0.0045 0.0653 0.0653
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0011 0.0073 0.0073
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0055 0.0835 0.1218
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.011 0.013
Echinococcus granulosus neuropeptide s receptor 0.0008 0.0032 0.0028
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0055 0.0835 0.3398
Brugia malayi Globin family protein 0.0009 0.004 0.0054
Loa Loa (eye worm) hypothetical protein 0.001 0.0069 0.0089
Echinococcus granulosus histone lysine methyltransferase setb 0.0062 0.0948 0.0944
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0031 0.0426 0.0422
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0544 0.0659
Loa Loa (eye worm) ICD-1 protein 0.0024 0.0307 0.042
Loa Loa (eye worm) hypothetical protein 0.0052 0.0773 0.1067
Echinococcus multilocularis transcription factor btf3 0.0024 0.0307 0.0303
Brugia malayi Sulfatase family protein 0.0009 0.0039 0.0053
Trichomonas vaginalis bromodomain-containing protein, putative 0.0014 0.0132 0.0158
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0551 0.0547
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0141 0.0137
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0071 0.0083
Onchocerca volvulus 0.001 0.0054 0.0054
Brugia malayi MH2 domain containing protein 0.0124 0.2003 0.2779
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Toxoplasma gondii selenide, water dikinase 0.0015 0.0141 0.0496
Brugia malayi regulator of G-protein signaling rgs-7 0.0007 0.0004 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0326 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0034 0.003
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0015 0.0141 0.0137
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.1853
Brugia malayi MH1 domain containing protein 0.0008 0.0034 0.0046
Mycobacterium leprae conserved hypothetical protein 0.0028 0.0372 0.0491
Plasmodium falciparum glycogen synthase kinase 3 0.0041 0.0588 0.2057
Trypanosoma brucei hypothetical protein, conserved 0.0015 0.0141 0.031
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0516 0.0512
Echinococcus granulosus alpha 1A adrenergic receptor 0.0008 0.0032 0.0028
Brugia malayi M-phase phosphoprotein, mpp8 0.0035 0.0495 0.0685
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0081 0.0111
Mycobacterium tuberculosis Conserved protein 0.0026 0.0326 0.0424
Brugia malayi MH2 domain containing protein 0.0008 0.0034 0.0046
Trypanosoma brucei hypothetical protein, conserved 0.0026 0.0326 0.1033
Echinococcus granulosus dna polymerase eta 0.0059 0.0898 0.0894
Brugia malayi Steroid receptor seven-up type 2 0.0007 0.001 0.0013
Onchocerca volvulus 0.0008 0.0032 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0032 0.0039
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.3713
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0008 0.0032 0.0028
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3085
Echinococcus multilocularis neuropeptide FF receptor 2 0.0008 0.0032 0.0028
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0249 0.4142 0.4139
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0028
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0034 0.0041
Brugia malayi Regulator of G protein signaling domain containing protein 0.0007 0.0004 0.0005
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0044 0.0641 0.233
Leishmania major hypothetical protein, conserved 0.0026 0.0326 0.1109
Mycobacterium leprae Probable lipase LipE 0.0026 0.0326 0.0422
Echinococcus multilocularis cyclin dependent kinase 5 activator 1 0.0108 0.1734 0.1731
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0071 0.0083
Mycobacterium leprae Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) 0.0391 0.6575 0.9654
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0039 0.055 0.0546
Loa Loa (eye worm) TYRA-2 protein 0.0008 0.0032 0.0039
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0009 0.0039 0.0044
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.011 0.0188
Schistosoma mansoni regulator of G protein signaling 0.0007 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0864 0.3197
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.2003 0.2776
Brugia malayi beta-lactamase 0.0026 0.0326 0.0451
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0143 0.2332 0.3387
Plasmodium vivax hypothetical protein, conserved 0.0026 0.0326 0.1033
Brugia malayi sulfakinin receptor protein 0.0008 0.0032 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3026
Onchocerca volvulus Netrin receptor homolog 0.0015 0.014 0.0158
Echinococcus granulosus glutamate synthase 0.0015 0.0141 0.0137
Loa Loa (eye worm) hypothetical protein 0.0052 0.0773 0.1067
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0004 0.0002
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0015 0.0141 0.0194
Loa Loa (eye worm) hypothetical protein 0.002 0.0226 0.0308
Echinococcus granulosus intermediate filament protein 0.0055 0.0836 0.0832
Trypanosoma cruzi trypanothione reductase, putative 0.0055 0.0835 0.3026
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0226 0.0226
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0098 0.1555 0.2238
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0041 0.0588 0.0584
Schistosoma mansoni dishevelled 0.0007 0.0011 0.0011
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0034 0.0462 0.1638
Trichomonas vaginalis DNA helicase recq, putative 0.0064 0.0989 0.1201
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.125 0.4751
Schistosoma mansoni microtubule-associated protein tau 0.0592 1 1
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0978 0.1353
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0217 0.0272
Trichomonas vaginalis mercuric reductase, putative 0.0055 0.0835 0.1014
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0012 0.0095 0.032
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0122 0.0234
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0031 0.0426 0.0426
Schistosoma mansoni hypothetical protein 0.0009 0.004 0.004
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0038 0.0539 0.0738
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0551 0.0547
Trichomonas vaginalis purine nucleoside phosphorylase I, putative 0.0391 0.6575 0.8004
Trichomonas vaginalis purine nucleoside phosphorylase, putative 0.0081 0.1274 0.1548
Mycobacterium ulcerans nitrate/nitrite response regulator protein NarL 0.0036 0.0513 0.0725
Mycobacterium ulcerans esterase/lipase LipP 0.0026 0.0326 0.0439
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0551 0.0667
Echinococcus multilocularis purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Brugia malayi hypothetical protein 0.001 0.0062 0.0085
Loa Loa (eye worm) hypothetical protein 0.0012 0.0095 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.011 0.013
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0013 0.0115 0.0111
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0551 0.1981
Loa Loa (eye worm) hypothetical protein 0.0026 0.0329 0.0451
Schistosoma mansoni cyclin-dependent kinase 5 activator 0.0108 0.1734 0.1734
Brugia malayi Dopamine receptor protein 1 0.0008 0.0032 0.0044
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0041 0.0598 0.0826
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Echinococcus granulosus g protein coupled receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0078 0.1223 0.1693
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0041 0.0588 0.081
Onchocerca volvulus 0.0008 0.0032 0.0027
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0028 0.0372 0.0372
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0007 0.001 0.0006
Loa Loa (eye worm) Smad1 0.0008 0.0034 0.0041
Treponema pallidum fructose-bisphosphate aldolase 0.02 0.3299 1
Schistosoma mansoni bifunctional dihydrofolate reductase-thymidylate synthase 0.0109 0.1759 0.1759
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0023 0.0284 0.0284
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0141 0.0496
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0007 0.001 0.0006
Onchocerca volvulus 0.0008 0.0032 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0015 0.0141 0.0137
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Echinococcus granulosus lysine specific demethylase 6a 0.0011 0.0073 0.0068
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3026
Giardia lamblia UPL-1 0.0081 0.1274 0.189
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0544 0.0755
Loa Loa (eye worm) hypothetical protein 0.0007 0.0011 0.001
Entamoeba histolytica hypothetical protein 0.0081 0.1274 0.3854
Brugia malayi MH2 domain containing protein 0.0008 0.0034 0.0046
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0544 0.1888
Entamoeba histolytica MTA/SAH nucleosidase, putative 0.0081 0.1274 0.3854
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0007 0.0016 0.0021
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0039 0.055 0.0546
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.001 0.0054 0.005
Plasmodium vivax purine nucleoside phosphorylase, putative 0.0081 0.1274 0.4742
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0015 0.0141 0.031
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0405 0.6809 1
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0551 0.0763
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0015 0.0141 0.015
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0015 0.0141 0.0156
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0019 0.0209 0.0657
Schistosoma mansoni methylthioadenosine phosphorylase 0.0081 0.1274 0.1274
Schistosoma mansoni hypothetical protein 0.0173 0.2837 0.2837
Echinococcus granulosus peptide allatostatin:somatostatin 0.0008 0.0032 0.0028
Chlamydia trachomatis AMP nucleosidase 0.0081 0.1274 0.5333
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0019 0.0209 0.0657
Brugia malayi purine nucleoside phosphorylase I, inosine and guanosine-specific family protein 0.0391 0.6575 0.9125
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0247 0.4104 0.5694
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0428 0.7205 1
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0015 0.0141 0.031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Schistosoma mansoni smad1 5 8 and 0.0008 0.0034 0.0034
Mycobacterium ulcerans bifunctional Mta/Sah nucleosidase Mtn 0.0081 0.1274 0.189
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0015 0.0141 0.019
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0154 0.2521 0.9617
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0008 0.0032 0.0028
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0551 0.0756
Schistosoma mansoni methylthioadenosine phosphorylase 0.0081 0.1274 0.1274
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.008 0.125 0.1246
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0007 0.001 0.0013
Echinococcus multilocularis g-protein coupled receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0034 0.0462 0.0636
Loa Loa (eye worm) hypoxia-induced factor 1 0.0153 0.2509 0.3478
Trypanosoma brucei unspecified product 0.0027 0.0346 0.111
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.014 0.0188
Chlamydia trachomatis endonuclease IV 0.0078 0.1223 0.5108
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0015 0.0141 0.0414
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0031 0.0426 0.0422
Brugia malayi Nuclear hormone receptor-like 1 0.0007 0.001 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Giardia lamblia Thioredoxin reductase 0.0015 0.0141 0.0156
Leishmania major trypanothione reductase 0.016 0.2619 1
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0016 0.0016
Toxoplasma gondii hypothetical protein 0.0019 0.0222 0.0807
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0055 0.0835 0.1176
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.004 0.0576 0.0572
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3085
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0544 0.0659
Brugia malayi hypothetical protein 0.0166 0.2728 0.3786
Echinococcus granulosus rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0052 0.0048
Mycobacterium leprae PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) 0.0109 0.1759 0.2539
Echinococcus granulosus 7TM GPCR rhodopsin 0.0008 0.0032 0.0028
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0032
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0081 0.1274 0.3854
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Trypanosoma cruzi NADH dehydrogenase, putative 0.0015 0.0141 0.031
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.001 0.0013
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0141 0.0168
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0017 0.0179 0.046
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0007 0.0011 0.0015
Trichomonas vaginalis CMGC family protein kinase 0.0019 0.0209 0.0251
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0217 0.0272
Entamoeba histolytica protein kinase domain containing protein 0.0041 0.0588 0.1771
Loa Loa (eye worm) hypothetical protein 0.0035 0.0495 0.0681
Mycobacterium tuberculosis Probable oxidoreductase 0.0405 0.6809 1
Brugia malayi PXA domain containing protein 0.0007 0.0004 0.0005
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0032 0.0028
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0026 0.0326 0.0393
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.008 0.125 0.4751
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0055 0.0835 0.3026
Toxoplasma gondii 6-phosphofructokinase 0.001 0.0065 0.0206
Mycobacterium tuberculosis Probable lipase LipD 0.0026 0.0326 0.0424
Loa Loa (eye worm) S-methyl-5'-thioadenosine phosphorylase MTAP 0.0081 0.1274 0.1763
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0055 0.0835 0.3026
Echinococcus granulosus Smad4 0.0008 0.0034 0.003
Trypanosoma brucei polo-like protein kinase 0.0034 0.0462 0.1567
Entamoeba histolytica cell division protein kinase 2, putative 0.0019 0.0209 0.0622
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0007 0.001 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.011 0.013
Loa Loa (eye worm) 6-phosphofructokinase 0.0038 0.0539 0.0742
Trypanosoma brucei cdc2-related kinase 1 0.0019 0.0209 0.0577
Schistosoma mansoni hypothetical protein 0.0049 0.0729 0.0729
Echinococcus granulosus g-protein coupled receptor 0.0008 0.0032 0.0028
Schistosoma mansoni smad 0.0008 0.0034 0.0034
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.0598 0.0598
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0068 0.1057 0.1057
Entamoeba histolytica rodhanase-like domain containing protein 0.001 0.0054 0.0152
Schistosoma mansoni intermediate filament proteins 0.0055 0.0836 0.0836
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.011 0.0188
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0544 0.054
Trichomonas vaginalis conserved hypothetical protein 0.0024 0.0307 0.037
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0121 0.1949 0.738
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Brugia malayi Probable ClpP-like protease 0.008 0.125 0.1734
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0015 0.0141 0.015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Loa Loa (eye worm) hypothetical protein 0.0014 0.0126 0.0169
Onchocerca volvulus 0.0008 0.0032 0.0027
Schistosoma mansoni alpha-1 adrenergic receptor 0.0008 0.0032 0.0032
Trichomonas vaginalis CMGC family protein kinase 0.0041 0.0588 0.0712
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0055 0.0835 0.3471
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0007 0.0011 0.0007
Echinococcus granulosus L aminoadipate semialdehyde 0.0028 0.0372 0.0368
Schistosoma mansoni apoferritin-2 0.0009 0.004 0.004
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0516 0.0715
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.004 0.0575 0.2008
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0217 0.0263
Echinococcus multilocularis neuropeptide Y receptor 0.0008 0.0032 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0007 0.001 0.0013
Echinococcus granulosus Pleckstrin G protein interacting region 0.0007 0.0011 0.0007
Echinococcus multilocularis microtubule associated protein 2 0.0592 1 1
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0015 0.0141 0.031
Trypanosoma brucei beta lactamase 0.0032 0.0428 0.1432
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Chlamydia trachomatis dihydrofolate reductase 0.0045 0.0652 0.2588
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0015 0.0141 0.0137
Schistosoma mansoni neuropeptide receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0166 0.2728 0.3783
Toxoplasma gondii LsmAD domain-containing protein 0.001 0.0062 0.0193
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0365 0.6114 0.8974
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0068 0.1057 0.1466
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0073 0.0095
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0551 0.0783
Schistosoma mansoni hypothetical protein 0.0018 0.0199 0.0199
Brugia malayi Rhodanese-like domain containing protein 0.001 0.0054 0.0075
Loa Loa (eye worm) hypothetical protein 0.0009 0.0042 0.0052
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.2003 0.2776
Schistosoma mansoni inositol monophosphatase 0.0015 0.0142 0.0142
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0034 0.0462 0.0458
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0008 0.0032 0.0032
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0019 0.0209 0.0285
Echinococcus granulosus histone acetyltransferase KAT2B 0.0014 0.0132 0.0128
Onchocerca volvulus 0.0055 0.0836 0.1006
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Onchocerca volvulus 0.0008 0.0032 0.0027
Schistosoma mansoni 6-phosphofructokinase 0.0038 0.0539 0.0539
Loa Loa (eye worm) jmjC domain-containing protein 0.0011 0.0073 0.0095
Loa Loa (eye worm) phosphofructokinase 0.0038 0.0539 0.0742
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0071 0.0083
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0781 0.0777
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0055 0.0835 0.1159
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0015 0.0142 0.0157
Schistosoma mansoni ap endonuclease 0.0019 0.0217 0.0217
Echinococcus multilocularis ecdysone induced protein 78C 0.0007 0.001 0.0006
Mycobacterium ulcerans hypothetical protein 0.0036 0.0513 0.0725
Echinococcus multilocularis glutamate synthase 0.0015 0.0141 0.0137
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.5227
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0032 0.0442 0.1652
Echinococcus multilocularis beta LACTamase domain containing family member 0.0026 0.0326 0.0322
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0015 0.0141 0.044
Schistosoma mansoni peptidase Clp (S14 family) 0.008 0.125 0.125
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0007 0.0011 0.0015
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Plasmodium vivax ferrodoxin reductase, putative 0.0015 0.0141 0.031
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0015 0.0141 0.0156
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0217 0.0687
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.011 0.013
Leishmania major methylthioadenosine phosphorylase, putative 0.0081 0.1274 0.4786
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Schistosoma mansoni neuropeptide f receptor 76f 0.0008 0.0032 0.0032
Mycobacterium tuberculosis Probable reductase 0.0365 0.6114 0.8974
Schistosoma mansoni aldehyde dehydrogenase 0.0041 0.0598 0.0598
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0217 0.0607
Onchocerca volvulus 0.0013 0.011 0.0121
Treponema pallidum pfs protein (pfs) 0.0081 0.1274 0.3787
Schistosoma mansoni myosin xvIII 0.0008 0.0032 0.0032
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0026 0.0326 0.0326
Echinococcus granulosus hypothetical protein 0.0008 0.0032 0.0028
Entamoeba histolytica thioredoxin reductase, putative 0.0015 0.0141 0.0414
Brugia malayi N-terminal motif family protein 0.0145 0.2361 0.3276
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0083 0.0079
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0041 0.0588 0.0584
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0038 0.0539 0.1531
Leishmania major hypothetical protein, conserved 0.0015 0.0141 0.0392
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0026 0.0326 0.0439
Echinococcus granulosus JmjC domain containing protein 4 0.0011 0.0073 0.0068
Toxoplasma gondii phosphorylase family protein 0.0081 0.1274 0.4843
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni hypothetical protein 0.0015 0.0141 0.0141
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0008 0.0032 0.0028
Echinococcus multilocularis segment polarity protein dishevelled 0.0007 0.0011 0.0007
Leishmania major hypothetical protein, conserved 0.0015 0.0141 0.0392
Onchocerca volvulus 0.0066 0.1016 0.1226
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0055 0.0835 0.3026
Toxoplasma gondii exonuclease III APE 0.0019 0.0217 0.0788
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0736 0.0736
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0063 0.0969 0.0965
Trichomonas vaginalis D-aminoacylase, putative 0.0026 0.0326 0.0393
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0041 0.0588 0.0588
Brugia malayi beta-lactamase family protein 0.0026 0.0326 0.0451
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0007 0.001 0.001
Schistosoma mansoni neuropeptide F-like receptor 0.0008 0.0032 0.0032
Brugia malayi Death domain containing protein 0.0015 0.014 0.0193
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0021 0.0243 0.0708
Echinococcus multilocularis smad 0.0008 0.0034 0.003
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0059 0.0899 0.3273
Schistosoma mansoni serine/threonine protein kinase 0.0034 0.0462 0.0462
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.007
Loa Loa (eye worm) hypothetical protein 0.0011 0.0073 0.0095
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0008 0.0032 0.0032
Echinococcus granulosus fmrfamide receptor 0.0008 0.0032 0.0028
Trypanosoma cruzi cdc2-related kinase 3 0.0019 0.0209 0.0577
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0015 0.0142 0.0417
Trichomonas vaginalis esterase, putative 0.0026 0.0326 0.0393
Echinococcus multilocularis fmrfamide receptor 0.0008 0.0032 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0015 0.0141 0.031
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0948 0.0948
Schistosoma mansoni methylthioadenosine phosphorylase 0.0081 0.1274 0.1274
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0039 0.055 0.0758
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0217 0.0607
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0551 0.1912
Entamoeba histolytica purine nucleoside phosphorylase, putative 0.0081 0.1274 0.3854
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Echinococcus multilocularis dihydrofolate reductase 0.0045 0.0652 0.0648
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0008 0.0032 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Mycobacterium tuberculosis Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) 0.0391 0.6575 0.9654
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0007 0.001 0.0006
Onchocerca volvulus Globin homolog 0.0009 0.004 0.0036
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0008 0.0032 0.0027
Echinococcus multilocularis musashi 0.0055 0.0836 0.0832
Brugia malayi hypoxia-induced factor 1 0.0153 0.2509 0.3481
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0544 0.1957
Brugia malayi Pre-SET motif family protein 0.0062 0.0948 0.1315
Giardia lamblia Kinase, CMGC CDK 0.0019 0.0209 0.026
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0028 0.0372 0.1383
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0008 0.0032 0.0028
Echinococcus granulosus smad 0.0008 0.0034 0.003
Trichomonas vaginalis phosphofructokinase, putative 0.0038 0.0539 0.0653
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0007 0.001 0.001
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0007 0.001 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0346 0.111
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0007 0.0004 0.0004
Trypanosoma brucei protein kinase, putative 0.0041 0.0588 0.2057
Echinococcus multilocularis purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0039 0.055 0.0546
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0023 0.0284 0.087
Mycobacterium ulcerans NADH dehydrogenase 0.0015 0.0141 0.0156
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0055 0.0835 0.3085
Treponema pallidum ATP-dependent DNA helicase 0.002 0.0226 0.0572
Trypanosoma cruzi hypothetical protein, conserved 0.0026 0.0326 0.1033
Schistosoma mansoni ferritin 0.0009 0.004 0.004
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0095 0.013
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0008 0.0032 0.0032
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0544 0.054
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0007 0.001 0.0013
Brugia malayi Regulator of G protein signaling domain containing protein 0.0007 0.0004 0.0005
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Brugia malayi beta-NAC-like protein 0.0024 0.0307 0.0425
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni survival motor neuron protein 0.0049 0.0729 0.0729
Echinococcus granulosus histone acetyltransferase KAT2B 0.0047 0.0692 0.0688
Trypanosoma cruzi cdc2-related kinase 3 0.0019 0.0209 0.0577
Brugia malayi hypothetical protein 0.0241 0.4003 0.5555
Loa Loa (eye worm) hypothetical protein 0.0021 0.024 0.0328
Schistosoma mansoni cpg binding protein 0.0031 0.0418 0.0418
Schistosoma mansoni inositol monophosphatase 0.0015 0.0142 0.0142
Echinococcus granulosus death domain containing protein 0.0015 0.014 0.0136
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0007 0.001 0.0006
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0019 0.0209 0.0759
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0065 0.0076
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0063 0.0969 0.1344
Echinococcus multilocularis orexin receptor type 2 0.0008 0.0032 0.0028
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.001 0.0054 0.0063
Mycobacterium ulcerans aldehyde dehydrogenase 0.0041 0.0598 0.0855
Schistosoma mansoni retinoic acid receptor RXR 0.0007 0.001 0.001
Loa Loa (eye worm) glutaminase 0.0205 0.3386 0.4696
Echinococcus multilocularis dnaJ subfamily B 0.0417 0.7004 0.7003
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0023 0.0284 0.087
Plasmodium vivax 6-phosphofructokinase, putative 0.001 0.0065 0.0014
Leishmania major ATP-dependent phosphofructokinase 0.0038 0.0539 0.1935
Loa Loa (eye worm) hypothetical protein 0.0039 0.055 0.0758
Mycobacterium tuberculosis Probable transcriptional regulatory protein 0.0036 0.0513 0.07
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0604 0.0833
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0551 0.0756
Schistosoma mansoni regulator of G protein signaling 0.0007 0.0004 0.0004
Echinococcus multilocularis neuropeptide s receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0054 0.0819 0.1131
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0095 0.013
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.014 0.014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Leishmania major nucleoside phosphorylase-like protein 0.0081 0.1274 0.4786
Trypanosoma cruzi transcription factor btf3, putative 0.0024 0.0307 0.0959
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0015 0.0141 0.015
Loa Loa (eye worm) hypothetical protein 0.0026 0.0326 0.0447
Trypanosoma brucei unspecified product 0.0027 0.0346 0.111
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Treponema pallidum purine nucleoside phosphorylase (deoD) 0.0081 0.1274 0.3787
Trypanosoma cruzi DNA polymerase eta, putative 0.0032 0.0442 0.1488
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0007 0.0004 0.0004
Brugia malayi photoreceptor-specific nuclear receptor 0.0007 0.001 0.0013
Trichomonas vaginalis phosphofructokinase, putative 0.0038 0.0539 0.0653
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Schistosoma mansoni coup transcription factor 0.0007 0.001 0.001
Echinococcus multilocularis thymidylate synthase 0.0109 0.1759 0.1755
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.001 0.0065 0.0078
Trypanosoma cruzi cdc2-related kinase 1 0.0019 0.0209 0.0577
Mycobacterium ulcerans epimerase 0.0021 0.024 0.0308
Mycobacterium tuberculosis Conserved protein 0.0026 0.0326 0.0424
Onchocerca volvulus 0.0026 0.0326 0.0384
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.011 0.0271
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0041 0.0598 0.2165
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0034 0.0041
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0008 0.0032 0.0028
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0055 0.0835 0.3026
Leishmania major protein kinase, putative 0.0017 0.0175 0.0524
Brugia malayi hypothetical protein 0.0007 0.0004 0.0005
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.0562 0.2112
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0544 0.1888
Brugia malayi Protein kinase domain containing protein 0.0015 0.0152 0.0209
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0018 0.0202 0.0197
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.001 0.0065 0.0014
Brugia malayi steroid hormone receptor 0.0007 0.001 0.0013
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0544 0.054
Echinococcus granulosus lamin 0.0055 0.0836 0.0832
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0015 0.0141 0.0137
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0007 0.001 0.0013
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0039 0.055 0.2065
Echinococcus multilocularis rhodopsin orphan GPCR 0.0008 0.0032 0.0028
Brugia malayi hypothetical protein 0.0009 0.004 0.0054
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0015 0.0141 0.031
Echinococcus multilocularis somatostatin receptor 0.0008 0.0032 0.0028
Leishmania major DNA polymerase kappa, putative 0.0039 0.0551 0.1981
Brugia malayi Protein kinase domain containing protein 0.0019 0.0209 0.0289
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0008 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0038 0.0544 0.075
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0055 0.0835 0.316
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0015 0.0142 0.0499
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0023 0.0284 0.028
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.02 0.3299 1
Onchocerca volvulus 0.0009 0.004 0.0036
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0143 0.2332 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0064 0.0974 0.1381
Echinococcus multilocularis neuropeptides capa receptor 0.0008 0.0032 0.0028
Brugia malayi thymidylate synthase 0.0109 0.1759 0.244
Echinococcus multilocularis purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0864 0.3139
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Brugia malayi putative neuropeptide receptor 0.0008 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0055 0.0835 0.3026
Loa Loa (eye worm) thymidylate synthase 0.0109 0.1759 0.2437
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0008 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0026 0.0329 0.0451
Mycobacterium ulcerans lipoprotein LpqF 0.0032 0.0428 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.011 0.013
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0781 0.1095
Loa Loa (eye worm) hypothetical protein 0.0015 0.0142 0.0191
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0008 0.0032 0.0044
Echinococcus multilocularis purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0217 0.0543
Trichomonas vaginalis glutamate synthase, putative 0.0015 0.0141 0.0168
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0007 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0052 0.0048
Loa Loa (eye worm) neuropeptide F receptor 0.0008 0.0032 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0551 0.1912
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0551 0.0551
Mycobacterium ulcerans thymidylate synthase 0.0109 0.1759 0.2631
Brugia malayi AKH receptor 0.0008 0.0032 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.02 0.3299 0.4014
Giardia lamblia 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase 0.0081 0.1274 0.189
Loa Loa (eye worm) hypothetical protein 0.0045 0.0666 0.0919
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0217 0.0607
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0065 0.0076
Brugia malayi intracellular kinase 0.0041 0.0588 0.0815
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0015 0.0141 0.0168
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0068 0.1057 0.3944
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0217 0.0295
Onchocerca volvulus 0.0041 0.0588 0.0704
Leishmania major phosphopantetheinyl transferase-like protein 0.0028 0.0372 0.1288
Echinococcus multilocularis Smad4 0.0008 0.0034 0.003
Echinococcus multilocularis uridine phosphorylase 1 0.0081 0.1274 0.127
Brugia malayi jmjC domain containing protein 0.0011 0.0073 0.01
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0041 0.0588 0.2057
Giardia lamblia NADH oxidase lateral transfer candidate 0.0055 0.0835 0.1218
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0389 0.0535
Schistosoma mansoni histamine h1 receptor 0.0008 0.0032 0.0032
Brugia malayi regulator of G-protein signaling egl-10 0.0014 0.0126 0.0174
Echinococcus granulosus cyclin dependent kinase 0.0019 0.0209 0.0205
Echinococcus multilocularis phd:f box containing protein 0.0011 0.0073 0.0068
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0075 0.1171 0.1167
Echinococcus granulosus biogenic amine 5HT receptor 0.0008 0.0032 0.0028
Echinococcus granulosus phd:f box containing protein 0.0011 0.0073 0.0068
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0551 0.1912
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0358 0.0977
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0551 0.0551
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0015 0.0141 0.0156
Echinococcus multilocularis beta adrenergic receptor kinase 0.0007 0.0016 0.0012
Onchocerca volvulus 0.0008 0.0032 0.0027
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0217 0.0607
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0011 0.0073 0.0043
Schistosoma mansoni amine GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0062 0.0948 0.0944
Trichomonas vaginalis CAMK family protein kinase 0.0034 0.0462 0.0559
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0018 0.0202 0.0202
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0007 0.0016 0.0016
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0043 0.0629 0.0625
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0836 0.1155
Brugia malayi Melatonin receptor type 1A 0.0008 0.0032 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.001 0.0009
Mycobacterium leprae conserved hypothetical protein 0.0026 0.0326 0.0422
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0015 0.0141 0.015
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0063 0.0969 0.134
Echinococcus multilocularis dro:myosuppressin receptor 0.0008 0.0032 0.0028
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0008 0.0032 0.0028
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.0045 0.0652 0.0905
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0028 0.0372 0.1383
Schistosoma mansoni serine/threonine protein kinase 0.0007 0.0016 0.0016
Schistosoma mansoni biogenic amine (5HT) receptor 0.0008 0.0032 0.0032
Brugia malayi jmjC domain containing protein 0.004 0.0576 0.0798
Echinococcus granulosus netrin receptor unc 5 0.0015 0.014 0.0136
Echinococcus granulosus transcription factor btf3 0.0024 0.0307 0.0303
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0015 0.0141 0.0168
Trypanosoma brucei NADH dehydrogenase 0.0015 0.0141 0.031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0007 0.001 0.0006
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0551 0.0783
Mycobacterium tuberculosis Probable transcriptional regulatory protein (probably LuxR/UhpA-family) 0.0036 0.0513 0.07
Schistosoma mansoni glutaminase 0.0205 0.3386 0.3386
Schistosoma mansoni jumonji domain containing protein 0.004 0.0576 0.0576
Echinococcus granulosus regulator of G protein signaling 7 0.0014 0.0126 0.0122
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.0045 0.0652 0.0904
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0154 0.2521 0.9621
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.011 0.0146
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.011 0.0105
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0068 0.1057 0.1053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0071 0.0083
Schistosoma mansoni globin X 0.0009 0.004 0.004
Mycobacterium ulcerans hypothetical protein 0.0064 0.0974 0.1431
Echinococcus multilocularis lysine specific demethylase 6a 0.0011 0.0073 0.0068
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0895 0.3389
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0015 0.0141 0.0137
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0026 0.0326 0.0447
Brugia malayi uridine phosphorylase family protein 0.0081 0.1274 0.1768
Echinococcus multilocularis lamin 0.0055 0.0836 0.0832
Plasmodium vivax thioredoxin reductase, putative 0.016 0.2619 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0781 0.1096
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0008 0.0032 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0018 0.0202 0.0202
Trichomonas vaginalis phosphofructokinase, putative 0.0038 0.0539 0.0653
Giardia lamblia Kinase, CMGC CDK 0.0019 0.0209 0.026
Echinococcus granulosus neuropeptide FF receptor 2 0.0008 0.0032 0.0028
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0007 0.0011 0.0011
Trypanosoma brucei uridine phosphorylase 0.0081 0.1274 0.4742
Schistosoma mansoni kinase 0.0017 0.0186 0.0186
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0043 0.0629 0.0625
Echinococcus granulosus purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0544 0.0544
Schistosoma mansoni axis inhibition protein axin 0.0007 0.0004 0.0004
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0062 0.0948 0.0948
Loa Loa (eye worm) hypothetical protein 0.0059 0.0898 0.1241
Brugia malayi MTAP 0.0081 0.1274 0.1768
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.1853
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0039 0.055 0.0762
Schistosoma mansoni steroid hormone receptor ad4bp 0.0007 0.001 0.001
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0055 0.0835 0.3026
Toxoplasma gondii phosphofructokinase domain-containing protein 0.001 0.0065 0.0206
Mycobacterium ulcerans beta-lactamase 0.0026 0.0326 0.0439
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0405 0.6809 1
Mycobacterium ulcerans monooxygenase 0.0009 0.004 0.0001
Mycobacterium ulcerans hypothetical protein 0.0026 0.0326 0.0439
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0055 0.0835 0.1218
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0365 0.6114 0.8974
Trichomonas vaginalis phosphofructokinase, putative 0.001 0.0065 0.0076
Schistosoma mansoni regulator of G protein signaling 0.0007 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Schistosoma mansoni sulfide quinone reductase 0.0015 0.0141 0.0141
Trichomonas vaginalis cdc25b, putative 0.001 0.0054 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.011 0.013
Loa Loa (eye worm) hypothetical protein 0.0009 0.004 0.0049
Echinococcus granulosus jumonji domain containing 1A 0.0011 0.0073 0.0068
Brugia malayi serine/threonine-protein kinase plk-2 0.0034 0.0462 0.0641
Entamoeba histolytica hypothetical protein 0.0024 0.0307 0.0918
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Mycobacterium tuberculosis Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase 0.0081 0.1274 0.1824
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0008 0.0032 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0039 0.0044
Schistosoma mansoni glutamate synthase 0.0015 0.0141 0.0141
Schistosoma mansoni RAR-like nuclear receptor 0.0007 0.001 0.001
Onchocerca volvulus 0.0008 0.0032 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0012 0.0095 0.013
Loa Loa (eye worm) hypothetical protein 0.001 0.0054 0.007
Entamoeba histolytica recQ family helicase, putative 0.0019 0.0213 0.0635
Brugia malayi neuropeptide F receptor 0.0008 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus granulosus segment polarity protein dishevelled 0.0007 0.0011 0.0007
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0028 0.0372 0.0509
Toxoplasma gondii Purine nucleoside phosphorylase 0.0081 0.1274 0.4843
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Plasmodium falciparum JmjC domain-containing protein, putative 0.0011 0.0073 0.0043
Mycobacterium leprae conserved hypothetical protein 0.0021 0.024 0.0296
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.002 0.0226 0.0824
Trichomonas vaginalis glutathione reductase, putative 0.0055 0.0835 0.1014
Echinococcus granulosus cpg binding protein 0.0031 0.0418 0.0414
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0004 0.0002
Echinococcus multilocularis cpg binding protein 0.0031 0.0418 0.0414
Mycobacterium ulcerans two component transcriptional regulator 0.0036 0.0513 0.0725
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0015 0.0141 0.044
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0008 0.0032 0.0032
Echinococcus multilocularis purine nucleoside phosphorylase 0.031 0.519 0.5188
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0143 0.2332 1
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0015 0.0141 0.0168
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0015 0.0141 0.031
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0121 0.1949 0.738
Trichomonas vaginalis cdc25c, putative 0.001 0.0054 0.0063
Brugia malayi glutamate synthase 0.0015 0.0141 0.0194
Echinococcus granulosus lamin dm0 0.0055 0.0836 0.0832
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.002 0.0226 0.0643
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0011 0.0073 0.0235
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0154 0.2521 0.9625
Brugia malayi hypothetical protein 0.0052 0.0773 0.1072
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0008 0.0032 0.0039
Echinococcus granulosus transcription factor Dp 1 0.0013 0.0118 0.0114
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0015 0.0141 0.0496
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0008 0.0032 0.0028
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0048 0.0715 0.0711
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0043 0.0629 0.0625
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0066 0.1011 0.1435
Plasmodium falciparum thioredoxin reductase 0.0055 0.0835 0.3026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0326 0.0447
Schistosoma mansoni disulfide oxidoreductase 0.0015 0.0141 0.0141
Brugia malayi A-kinase anchor protein 10, precursor 0.0007 0.0004 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0346 0.111
Echinococcus granulosus neuropeptide receptor 0.0008 0.0032 0.0028
Loa Loa (eye worm) hypothetical protein 0.0108 0.1734 0.2403
Loa Loa (eye worm) hypothetical protein 0.0009 0.0039 0.0048
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus multilocularis neuropeptide receptor 0.0008 0.0032 0.0028
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0544 0.1639
Schistosoma mansoni hypothetical protein 0.0008 0.0032 0.0032
Schistosoma mansoni uridine phosphorylase 0.0081 0.1274 0.1274
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.008 0.125 0.4647
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0015 0.0141 0.0137
Schistosoma mansoni ferritin 0.0009 0.004 0.004
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0014 0.0132 0.0158
Loa Loa (eye worm) glutaminase 2 0.0205 0.3386 0.4696
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0015 0.0141 0.0137
Mycobacterium ulcerans bacterioferritin BfrB 0.0009 0.004 0.0001
Echinococcus granulosus thymidylate synthase 0.0109 0.1759 0.1755
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0052 0.0048
Loa Loa (eye worm) hypothetical protein 0.0008 0.0032 0.0039
Echinococcus granulosus orexin receptor type 2 0.0008 0.0032 0.0028
Onchocerca volvulus 0.001 0.0054 0.0054
Trypanosoma cruzi polo-like protein kinase, putative 0.0034 0.0462 0.1567
Loa Loa (eye worm) hypothetical protein 0.0009 0.0042 0.0052
Schistosoma mansoni cpg binding protein 0.0031 0.0418 0.0418
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0055 0.0835 0.3026
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0004 0.0002
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0023 0.0284 0.028
Schistosoma mansoni thyroid hormone receptor 0.0007 0.001 0.001
Plasmodium falciparum protein kinase 5 0.0019 0.0209 0.0577
Mycobacterium tuberculosis Probable monooxygenase 0.0009 0.004 0.0001
Echinococcus granulosus neuropeptide receptor 0.0008 0.0032 0.0028
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0008 0.0032 0.0032
Schistosoma mansoni serine/threonine protein kinase 0.0019 0.0209 0.0209
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0055 0.0835 0.3471
Echinococcus multilocularis jumonji domain containing 1A 0.0011 0.0073 0.0068
Leishmania major DNA polymerase kappa, putative 0.0012 0.0095 0.0214
Onchocerca volvulus 0.0008 0.0032 0.0027
Loa Loa (eye worm) hypothetical protein 0.0145 0.2361 0.3273
Entamoeba histolytica rodhanase-like domain containing protein 0.001 0.0054 0.0152
Entamoeba histolytica serine/threonine protein kinase, putative 0.0034 0.0462 0.139
Loa Loa (eye worm) hypothetical protein 0.0241 0.4003 0.5553
Loa Loa (eye worm) G-protein coupled receptor 0.0008 0.0032 0.0039
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0048 0.0715 0.0715
Brugia malayi ImpB/MucB/SamB family protein 0.0059 0.0898 0.1245
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0004 0.0002
Treponema pallidum uridine phosphorylase (udp) 0.0081 0.1274 0.3787
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0551 0.1658
Echinococcus granulosus G protein coupled receptor 139 0.0008 0.0032 0.0028
Brugia malayi hypothetical protein 0.0008 0.0032 0.0044
Loa Loa (eye worm) uridine phosphorylase 0.0081 0.1274 0.1763
Loa Loa (eye worm) hypothetical protein 0.0015 0.0141 0.019
Mycobacterium ulcerans 5'-methylthioadenosine phosphorylase 0.0081 0.1274 0.189
Brugia malayi beta-lactamase family protein 0.0026 0.0326 0.0451
Loa Loa (eye worm) hypothetical protein 0.0007 0.001 0.0008
Trichomonas vaginalis 6-phosphofructokinase, putative 0.001 0.0065 0.0076
Echinococcus multilocularis purine nucleoside phosphorylase 0.0391 0.6575 0.6573
Echinococcus multilocularis L aminoadipate semialdehyde 0.0028 0.0372 0.0368
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0015 0.0141 0.044

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 4.4 uM In vitro inhibitory activity against acyl carrier protein synthase (AcpS) in Bacillus subtilis GST-Acp-HTRFassay ChEMBL. 14684293
IC50 (binding) = 4.4 uM In vitro inhibitory activity against acyl carrier protein synthase (AcpS) in Bacillus subtilis GST-Acp-HTRFassay ChEMBL. 14684293
MIC (functional) = 25 uM Minimum inhibitory concentration required against Bacillus subtilis was determined ChEMBL. 14684293
MIC (functional) = 25 uM Minimum inhibitory concentration required against Streptococcus pneumoniae ChEMBL. 14684293
MIC (functional) = 100 uM Minimum inhibitory concentration required against Escherichia faecalis VRE strain was determined ChEMBL. 14684293
MIC (functional) = 200 uM Minimum inhibitory concentration required against Escherichia faecalis ATCC strain was determined ChEMBL. 14684293

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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