Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | poly (ADP-ribose) polymerase 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0095 | 0.2419 | 0.5 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0258 | 0.9523 | 1 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0174 | 0.5827 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0249 | 0.9098 | 0.9486 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0095 | 0.2419 | 0.4152 |
Brugia malayi | WGR domain containing protein | 0.0174 | 0.5827 | 0.4797 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0095 | 0.2419 | 0.1413 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.2419 | 0.1419 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0125 | 0.372 | 0.6384 |
Brugia malayi | nuclear hormone receptor | 0.0258 | 0.9523 | 1 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0095 | 0.2419 | 0.3464 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.018 | 0.6123 | 0.5 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0174 | 0.5827 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0136 | 0.4197 | 0.5892 |
Loa Loa (eye worm) | hypothetical protein | 0.0132 | 0.4021 | 0.3354 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0095 | 0.2419 | 0.5 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0174 | 0.5827 | 1 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0095 | 0.2419 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0136 | 0.4197 | 0.6873 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0174 | 0.5827 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.