Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | adenosine deaminase, putative | 0.4655 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0676 | 0.1415 | 0.1415 |
Brugia malayi | GnHR receptor homolog | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | fmrfamide receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | Dopamine receptor protein 1 | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0036 | 0.0035 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0002 | 0.5 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0052 | 0.0068 | 0.0143 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | AMP deaminase | 0.2172 | 0.4642 | 0.4642 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0095 | 0.0095 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0002 | 0.0002 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Leishmania major | AMP deaminase, putative,amp deaminase-like protein | 0.2172 | 0.4642 | 0.4641 |
Schistosoma mansoni | adenoreceptor | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0036 | 0.0036 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | amine GPCR | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0036 | 0.0035 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0065 | 0.0095 | 0.0094 |
Echinococcus granulosus | g protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0052 | 0.0067 | 0.0067 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0052 | 0.0068 | 0.0066 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.4655 | 1 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Entamoeba histolytica | adenosine deaminase, putative | 0.4655 | 1 | 1 |
Brugia malayi | RE15519p | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.009 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.0063 | 0.0133 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0095 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.009 |
Brugia malayi | Serotonin receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | opsin-like receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0032 | 0.0032 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | AMP deaminase 2 | 0.2172 | 0.4642 | 0.4642 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.4655 | 1 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | Melatonin receptor type 1A | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Echinococcus multilocularis | serotonin receptor | 0.0199 | 0.0384 | 0.0384 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0095 | 0.0095 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Leishmania major | trypanothione reductase | 0.005 | 0.0063 | 0.0062 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0036 | 0.0035 |
Schistosoma mansoni | lipoxygenase | 0.0057 | 0.0079 | 0.0079 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.2172 | 0.4642 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | g-protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0037 | 0.0036 | 0.0036 | |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0113 | 0.0201 | 0.0199 |
Echinococcus granulosus | g protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0113 | 0.0201 | 0.0165 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | amine GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.2172 | 0.4642 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0068 | 0.0143 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Echinococcus granulosus | sex peptide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0037 | 0.0037 | 0.0037 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0037 | 0.0037 | 0.0037 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0052 | 0.0068 | 0.0143 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Toxoplasma gondii | AMP deaminase | 0.2172 | 0.4642 | 0.4641 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0068 | 0.0068 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0032 | 0.0032 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Entamoeba histolytica | adenosine deaminase, putative | 0.4655 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.4655 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | biogenic amine receptor | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0113 | 0.0201 | 0.0199 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0036 | 0.0035 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.296 | 0.6343 | 0.6343 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0036 | 0.0075 |
Echinococcus granulosus | orexin receptor type 2 | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | g protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0063 | 0.0063 |
Mycobacterium tuberculosis | Probable reductase | 0.0113 | 0.0201 | 0.0199 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0063 | 0.0063 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0057 | 0.0079 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Schistosoma mansoni | amine GPCR | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0037 | 0.0036 | 0.0036 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0032 | 0.0032 |
Echinococcus multilocularis | adenosine deaminase | 0.4655 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.009 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0095 | 0.0202 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | AMP deaminase 2 homolog | 0.2172 | 0.4642 | 0.4642 |
Loa Loa (eye worm) | hypothetical protein | 0.296 | 0.6343 | 0.6343 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0063 | 0.0062 |
Brugia malayi | Dopamine receptor protein 2 | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0023 | 0.0006 | 0.0006 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0036 | 0.0035 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.0095 | 0.0095 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0199 | 0.0384 | 0.0384 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0036 | 0.0035 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | AMP deaminase 2 | 0.2172 | 0.4642 | 0.4642 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0052 | 0.0068 | 0.0068 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0036 | 0.0036 |
Entamoeba histolytica | AMP deaminase, putative | 0.2172 | 0.4642 | 0.4641 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0036 | 0.0036 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0063 | 0.0063 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.4655 | 1 | 1 |
Entamoeba histolytica | AMP deaminase, putative | 0.2172 | 0.4642 | 0.4641 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.1695 | 0.3612 | 0.7782 |
Brugia malayi | G-protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.0095 | 0.0094 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.4655 | 1 | 1 |
Onchocerca volvulus | 0.0037 | 0.0036 | 0.0036 | |
Mycobacterium ulcerans | adenosine deaminase | 0.4655 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0095 | 0.0095 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0002 | 0.0002 |
Treponema pallidum | adenosine deaminase | 0.4655 | 1 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.0199 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | neuropeptide F receptor | 0.0052 | 0.0067 | 0.0067 |
Leishmania major | adenine aminohydrolase | 0.4655 | 1 | 1 |
Plasmodium falciparum | adenosine deaminase | 0.4655 | 1 | 1 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0036 | 0.0035 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | g protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0199 | 0.0384 | 0.0384 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | AMP deaminase | 0.2172 | 0.4642 | 0.4642 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.2172 | 0.4642 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0126 | 0.0228 | 0.0226 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0095 | 0.0095 |
Schistosoma mansoni | biogenic amine receptor | 0.0052 | 0.0067 | 0.0067 |
Leishmania major | adenosine monophosphate deaminase, putative,AMP deaminase, putative | 0.2172 | 0.4642 | 0.4641 |
Schistosoma mansoni | histamine h1 receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | G-protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0023 | 0.0006 | 0.0006 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | fmrfamide receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma brucei | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0113 | 0.0201 | 0.0199 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.0002 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.4655 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | serotonin receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0063 | 0.0091 | 0.0091 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0838 | 0.1765 | 0.1765 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0063 | 0.0063 |
Brugia malayi | larval opioid receptor | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0052 | 0.0067 | 0.0067 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0002 | 0.0002 |
Schistosoma mansoni | adenosine deaminase | 0.4655 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0113 | 0.0201 | 0.0199 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma brucei | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Leishmania major | AMP deaminase, putative,adenosine monophosphate deaminase-like protein | 0.2172 | 0.4642 | 0.4641 |
Brugia malayi | follicle stimulating hormone receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0036 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0384 | 0.0384 |
Echinococcus multilocularis | allatostatin A receptor | 0.0052 | 0.0067 | 0.0067 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0036 | 0.0035 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0126 | 0.0228 | 0.0192 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0036 | 0.0035 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.0091 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0036 | 0.0036 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0036 | 0.0035 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0256 | 0.0507 | 0.0507 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.009 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0036 | 0.0036 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | allatostatin A receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0068 | 0.0068 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0028 | 0.0028 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0036 | 0.0035 |
Trypanosoma brucei | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0057 | 0.0079 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | amine GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Plasmodium vivax | adenosine/AMP deaminase, putative | 0.2172 | 0.4642 | 0.4642 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0052 | 0.0067 | 0.0067 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0052 | 0.0068 | 0.0068 |
Schistosoma mansoni | myosin xvIII | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0036 | 0.0075 |
Echinococcus granulosus | adenosine deaminase | 0.4655 | 1 | 1 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0052 | 0.0067 | 0.0067 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0036 | 0.0035 |
Brugia malayi | MH2 domain containing protein | 0.0256 | 0.0507 | 0.0507 |
Echinococcus multilocularis | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0095 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0052 | 0.0067 | 0.0067 |
Leishmania major | hypothetical protein, conserved | 0.1695 | 0.3612 | 0.3611 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0477 | 0.0985 | 0.0985 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.0091 | 0.0091 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | adenosine monophosphate deaminase | 0.2172 | 0.4642 | 0.4642 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.296 | 0.6343 | 0.6343 |
Leishmania major | hypothetical protein, conserved | 0.0052 | 0.0068 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0063 | 0.0063 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0063 | 0.0063 |
Onchocerca volvulus | 0.1695 | 0.3612 | 0.3612 | |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | adenosine deaminase-related | 0.4655 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0036 | 0.0036 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.4655 | 1 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | amine GPCR | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0063 | 0.0091 | 0.0091 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0036 | 0.0035 |
Echinococcus multilocularis | somatostatin receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | glutathione reductase | 0.005 | 0.0063 | 0.0063 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0126 | 0.0228 | 0.0226 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | sulfakinin receptor protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0238 | 0.047 | 0.0469 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | opsin-like receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0036 | 0.0035 |
Brugia malayi | Serotonin receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | sex peptide receptor | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.296 | 0.6343 | 0.6343 |
Brugia malayi | ORL1-like opioid receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0199 | 0.0384 | 0.0384 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | putative neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0002 | 0.0002 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0068 | 0.0068 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0036 | 0.0035 |
Schistosoma mansoni | neuropeptide receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | fmrfamide receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | somatostatin receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | AKH receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | biogenic amine receptor | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0676 | 0.1415 | 0.1415 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0063 | 0.0062 |
Brugia malayi | Dopamine receptor | 0.0052 | 0.0067 | 0.0067 |
Plasmodium falciparum | AMP deaminase, putative | 0.2172 | 0.4642 | 0.4642 |
Brugia malayi | G protein-coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.1695 | 0.3612 | 0.3612 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0036 | 0.0036 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0036 | 0.0035 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0256 | 0.0507 | 0.0507 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0036 | 0.0036 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0036 | 0.0036 |
Echinococcus granulosus | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0036 | 0.0035 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0052 | 0.0067 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0052 | 0.0067 | 0.0067 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0036 | 0.0036 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0036 | 0.0035 |
Trypanosoma cruzi | AMP deaminase, putative | 0.2172 | 0.4642 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0113 | 0.0201 | 0.0199 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0676 | 0.1415 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.4655 | 1 | 1 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0126 | 0.0228 | 0.0226 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Brugia malayi | neuropeptide F receptor | 0.0052 | 0.0067 | 0.0067 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0063 | 0.0133 |
Leishmania major | AMP deaminase, putative | 0.2172 | 0.4642 | 0.4641 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0052 | 0.0067 | 0.0067 |
Echinococcus multilocularis | g protein coupled receptor | 0.0052 | 0.0067 | 0.0067 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.0091 | 0.009 |
Onchocerca volvulus | 0.0052 | 0.0067 | 0.0067 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0067 | 0.0067 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0067 | 0.0067 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 55 % | Effect on 5-hydroxytryptamine 1A receptor mediated inhibition of VIP-stimulated cAMP production at dose of 1 uM+ 3 uM 5-HT. | ChEMBL. | 8831769 |
Inhibition (functional) | = 65 % | Effect on 5-hydroxytryptamine 1A receptor mediated inhibition of VIP-stimulated cAMP production at dose of 50 uM | ChEMBL. | 8831769 |
Inhibition (functional) | = 68 % | Effect of the compound on 5-hydroxytryptamine 1A receptor mediated inhibition of VIP-stimulated cAMP production at dose of 0.1 uM + 1 uM 5-HT. | ChEMBL. | 8831769 |
Inhibition (functional) | = 90 % | Effect of the compound on 5-hydroxytryptamine 1A receptor mediated inhibition of VIP-stimulated cAMP production at dose of 1 uM | ChEMBL. | 8831769 |
Inhibition (functional) | = 98 % | Effect on 5-hydroxytryptamine 1A receptor mediated inhibition of VIP-stimulated cAMP production at dose of 0.05 uM | ChEMBL. | 8831769 |
Ki (binding) | = 177 nM | Binding affinity of the compound against rat hippocampal 5-hydroxytryptamine 1A (5-HT1A) receptor determined using [3H]-8-OH-DPAT as radioligand | ChEMBL. | 8831769 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.