Detailed information for compound 227021

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 695.827 | Formula: C34H58N5O8P
  • H donors: 3 H acceptors: 8 LogP: 2.62 Rotable bonds: 26
    Rule of 5 violations (Lipinski): 2
  • SMILES: CCCCCC(=O)N(CC(=O)N(CC(=O)N(CC(=O)N(CC(=O)N)CC(C)C)CC(C)C)CC(C)C)Cc1ccc(cc1)CP(=O)(O)O
  • InChi: 1S/C34H58N5O8P/c1-8-9-10-11-31(41)39(19-28-12-14-29(15-13-28)24-48(45,46)47)23-34(44)38(18-27(6)7)22-33(43)37(17-26(4)5)21-32(42)36(16-25(2)3)20-30(35)40/h12-15,25-27H,8-11,16-24H2,1-7H3,(H2,35,40)(H2,45,46,47)
  • InChiKey: MUHPVXYCLAENAK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum FACT complex subunit SPT16, putative 0.0023 0.0029 0.0027
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0061 0.0474
Giardia lamblia Fructose-bisphosphate aldolase 0.0282 0.0663 1
Echinococcus multilocularis aldo keto reductase 0.0066 0.0134 0.0132
Echinococcus multilocularis aldehyde reductase 0.0047 0.0087 0.0085
Echinococcus granulosus flap endonuclease 1 0.0031 0.0048 0.0046
Loa Loa (eye worm) neuropeptide F receptor 0.0219 0.0508 0.0508
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Echinococcus granulosus cpg binding protein 0.0098 0.0211 0.0209
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Schistosoma mansoni biogenic amine (5HT) receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis orexin receptor type 2 0.0219 0.0508 0.0506
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0219 0.0508 0.0506
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0022 0.0024
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0063 0.0126 0.0125
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0025 0.0034 0.0032
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0029 0.0043 0.004
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0219 0.0508 0.0508
Schistosoma mansoni blooms syndrome DNA helicase 0.0013 0.0005 0.0003
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) 0.0023 0.0029 0.0023
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0098 0.0096
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0167 0.0165
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0219 0.0508 0.0508
Echinococcus multilocularis cathepsin L 0.0014 0.0007 0.0005
Schistosoma mansoni steroid hormone receptor ad4bp 0.0063 0.0126 0.0125
Leishmania major aminopeptidase P, putative,metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0027
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Echinococcus granulosus neuroglian 0.0027 0.0038 0.0036
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0066 0.0066
Echinococcus multilocularis 0.0028 0.0041 0.0039
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.005 0.005
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0269 0.0266
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.006 0.006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0219 0.0508 0.0506
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0219 0.0508 0.0506
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0038 0.0065 0.0063
Brugia malayi Myosin head containing protein 0.0018 0.0016 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0007 0.0006
Brugia malayi cathepsin L-like precursor 0.0019 0.0018 0.0016
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0028 0.0041 0.0034
Echinococcus granulosus neuropeptide Y receptor 0.0219 0.0508 0.0506
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0031 0.0047 0.0045
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0125 0.0123
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0036 0.0061 0.0075
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0028 0.0041 0.0038
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0097 0.021 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0049 0.0092 0.0092
Onchocerca volvulus Histone deacetylase 10 homolog 0.0053 0.0102 0.01
Schistosoma mansoni nuclear receptor 0.003 0.0045 0.0043
Echinococcus multilocularis neuropeptides capa receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis mercuric reductase, putative 0.0036 0.0061 0.0061
Giardia lamblia Methionine aminopeptidase 0.0188 0.0432 0.6498
Echinococcus multilocularis Ankyrin 0.0017 0.0015 0.0013
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0003 0.0003
Echinococcus multilocularis tar DNA binding protein 0.013 0.029 0.0288
Schistosoma mansoni transcription factor LCR-F1 0.0116 0.0256 0.0254
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0188 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) phosphatidylinositol 3 0.0054 0.0104 0.0104
Entamoeba histolytica aldose reductase, putative 0.0066 0.0134 0.0131
Onchocerca volvulus 0.0028 0.0041 0.0039
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0075
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.003 0.0028
Loa Loa (eye worm) oxidoreductase 0.0066 0.0134 0.0134
Schistosoma mansoni septate junction protein 0.0025 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0015
Trypanosoma brucei methionine aminopeptidase, type I, putative 0.0023 0.0029 0.0034
Echinococcus multilocularis serotonin receptor 0.0219 0.0508 0.0506
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.036 0.0852 0.597
Echinococcus multilocularis leucine rich repeat containing protein 4 0.0025 0.0034 0.0032
Echinococcus granulosus 3'partial|cell adhesion molecule:down regulated by 0.0025 0.0034 0.0032
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0036 0.0061 0.0055
Loa Loa (eye worm) hypothetical protein 0.0121 0.0269 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.005 0.005
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0066 0.0134 0.0128
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.004 0.004
Schistosoma mansoni neuroglian 0.0027 0.0038 0.0036
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Echinococcus multilocularis G protein coupled receptor 139 0.0219 0.0508 0.0506
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0019 0.002 0.002
Echinococcus granulosus histone deacetylase 6 0.0053 0.0102 0.01
Schistosoma mansoni opsin-like receptor 0.0219 0.0508 0.0506
Plasmodium falciparum DNA repair protein REV1, putative 0.0014 0.0007 0.0004
Echinococcus granulosus sex peptide receptor 0.0219 0.0508 0.0506
Echinococcus granulosus biogenic amine 5HT receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Schistosoma mansoni cell adhesion molecule 0.0027 0.0038 0.0036
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0331 0.0329
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0048 0.009 0.009
Plasmodium falciparum cysteine repeat modular protein 1 0.0038 0.0065 0.0062
Trichomonas vaginalis adenosine deaminase, putative 0.4097 1 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.002 0.0022 0.0019
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0087 0.0087
Giardia lamblia Sgs1 DNA helicase, putative 0.0026 0.0036 0.0505
Treponema pallidum NADH oxidase 0.0036 0.0061 0.0058
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0019 0.0019 0.0019
Trichomonas vaginalis replication factor C large subunit, putative 0.002 0.0022 0.0022
Schistosoma mansoni DNA polymerase IV / kappa 0.0014 0.0007 0.0005
Schistosoma mansoni inositol monophosphatase 0.0027 0.004 0.0038
Echinococcus granulosus basement membrane specific heparan sulfate 0.0025 0.0034 0.0032
Loa Loa (eye worm) cytochrome P450 0.0028 0.0041 0.0041
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Echinococcus granulosus neuropeptide FF receptor 2 0.0219 0.0508 0.0506
Mycobacterium tuberculosis 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS) 0.0229 0.0533 0.0531
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0018
Leishmania major phosphatidylinositol 3-kinase, putative 0.0018 0.0016 0.0014
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0238 0.0556 0.0553
Trypanosoma cruzi trypanothione reductase, putative 0.0104 0.0228 0.0291
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0072 0.0069
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0022 0.0022
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0036 0.0061 0.0075
Schistosoma mansoni retinoic acid receptor RXR 0.0063 0.0126 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus granulosus Immunoglobulin subtype 0.0025 0.0034 0.0032
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0048 0.0048
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Trypanosoma cruzi cysteine peptidase, putative 0.0014 0.0007 0.0006
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Mycobacterium ulcerans epimerase 0.0024 0.0031 0.0025
Echinococcus granulosus histone deacetylase 6 0.0053 0.0102 0.01
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0066 0.0082
Loa Loa (eye worm) RecQ helicase 0.003 0.0045 0.0045
Schistosoma mansoni topbp1 0.002 0.0022 0.002
Giardia lamblia Aldose reductase 0.0066 0.0134 0.1987
Onchocerca volvulus 0.0049 0.0092 0.0089
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Brugia malayi Probable ClpP-like protease 0.0079 0.0167 0.0165
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0087 0.0085
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.3413 0.8325 0.8325
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0016 0.0016
Trypanosoma cruzi histone deacetylase, putative 0.0053 0.0102 0.0129
Echinococcus granulosus nuclear receptor nhr 48 0.003 0.0045 0.0043
Toxoplasma gondii hypothetical protein 0.0027 0.0039 0.0039
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.003 0.0045 0.0043
Echinococcus granulosus alpha 1A adrenergic receptor 0.0219 0.0508 0.0506
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Echinococcus granulosus cathepsin l1 0.0028 0.004 0.0038
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0015 0.0008 0.0006
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0045 0.0042
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0147 0.0332 0.0426
Schistosoma mansoni hypothetical protein 0.0012 0.0003 0.0001
Onchocerca volvulus Phospholipase A2 homolog 0.0073 0.015 0.0147
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0012 0.001
Leishmania major protein kinase, putative 0.0013 0.0004 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0269 0.0263
Leishmania major cathepsin L-like protease 0.0084 0.0178 0.0175
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0024 0.0031 0.0029
Brugia malayi hypothetical protein 0.0056 0.0109 0.0107
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0269 0.0267
Mycobacterium leprae Conserved hypothetical protein 0.0028 0.0041 0.0034
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0331 0.0329
Trypanosoma cruzi cysteine protease, putative 0.0014 0.0007 0.0006
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0046 0.0085 0.0082
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Mycobacterium ulcerans hypothetical protein 0.0164 0.0373 0.0367
Echinococcus multilocularis protein dispatched 1 0.0145 0.0328 0.0326
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Echinococcus granulosus histone deacetylase 8 0.0616 0.1481 0.1479
Brugia malayi Dopamine receptor protein 2 0.0219 0.0508 0.0506
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0027 0.004 0.004
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0066 0.0066
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0014 0.0011
Brugia malayi hypothetical protein 0.003 0.0045 0.0043
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.004 0.0038
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0061 0.0075
Toxoplasma gondii histone deacetylase HDAC2 0.0098 0.0211 0.0211
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.006 0.0057
Echinococcus multilocularis allatostatin A receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis Smad4 0.0017 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog 0.0187 0.0429 0.0427
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0097 0.021 0.0208
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0125 0.0125
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.0331 0.0329
Echinococcus granulosus nuclear receptor 2DBD gamma 0.003 0.0045 0.0043
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0014 0.0007 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0137 0.0137
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0075
Echinococcus granulosus peptide allatostatin:somatostatin 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0015 0.0013
Trypanosoma brucei Facilitates chromatin transcription complex subunit spt16 0.0023 0.0029 0.0034
Leishmania major DNA polymerase eta, putative 0.0076 0.0159 0.0157
Entamoeba histolytica methionine aminopeptidase, putative 0.0188 0.0432 0.0429
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0077 0.0077
Onchocerca volvulus 0.0219 0.0508 0.0505
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis histone deacetylase, putative 0.0098 0.0211 0.0211
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Leishmania major aldo-keto reductase-like protein 0.0066 0.0134 0.0131
Echinococcus multilocularis synaptojanin 1 0.0012 0.0003 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0065
Brugia malayi Immunoglobulin I-set domain containing protein 0.0027 0.0038 0.0036
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0041 0.0049
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0036 0.006 0.0053
Echinococcus multilocularis nibrin 0.002 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.0076 0.0159 0.0159
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0091 0.0196 0.0193
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0063 0.0126 0.0125
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.002 0.0022 0.0015
Entamoeba histolytica Xaa-Pro dipeptidase, putative 0.0023 0.0029 0.0027
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0022 0.0025 0.0023
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0219 0.0508 0.0506
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.029 0.029
Schistosoma mansoni tar DNA-binding protein 0.013 0.029 0.0288
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0002 0.0002
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.3172 0.7735 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0077 0.0077
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0023 0.0029 0.0027
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0062 0.0123 0.0121
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0006
Giardia lamblia NADH oxidase lateral transfer candidate 0.0036 0.0061 0.0879
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0121 0.0269 0.0269
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0028 0.0041 0.0034
Echinococcus granulosus roundabout 2 0.0027 0.0038 0.0036
Schistosoma mansoni cell adhesion molecule 0.0025 0.0034 0.0032
Schistosoma mansoni neutral sphingomyelinase 0.0012 0.0003 0.0001
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0028 0.0041 0.0038
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0028 0.0041 0.0034
Echinococcus multilocularis ubiquitin specific protease 41 0.0047 0.0087 0.0085
Echinococcus granulosus single minded 2 0.0025 0.0033 0.0031
Loa Loa (eye worm) ctsf protein 0.0028 0.004 0.004
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.003 0.0028
Loa Loa (eye worm) hypothetical protein 0.0047 0.0087 0.0087
Echinococcus granulosus neuropeptide receptor A26 0.0768 0.1852 0.185
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.0025 0.0034 0.0032
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0047 0.0087 0.0085
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0022 0.0027 0.0031
Toxoplasma gondii patched family protein 0.0018 0.0016 0.0016
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0119 0.0264 0.0261
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.002 0.0022 0.0015
Brugia malayi hypoxia-induced factor 1 0.0086 0.0183 0.0181
Brugia malayi nuclear receptor RXR 0.003 0.0045 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0048 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0219 0.0508 0.0506
Schistosoma mansoni potassium channel beta 0.0019 0.0019 0.0017
Schistosoma mansoni histone deacetylase 0.0098 0.0211 0.0209
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0025 0.0034 0.0032
Echinococcus granulosus ecdysone induced protein 78C 0.0063 0.0126 0.0125
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0019 0.0019 0.0017
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0088 0.0187 0.0185
Echinococcus granulosus Immunoglobulin 0.009 0.0193 0.0191
Brugia malayi RE15519p 0.0219 0.0508 0.0506
Brugia malayi histone deacetylase 3 (HD3) 0.0098 0.0211 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0022
Brugia malayi polk-prov protein 0.0014 0.0007 0.0005
Trypanosoma brucei metallo- peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0121 0.0269 0.0263
Loa Loa (eye worm) TAR-binding protein 0.013 0.029 0.029
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0284 0.0284
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Plasmodium falciparum aldo-keto reductase, putative 0.0019 0.0019 0.0016
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0063 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.0297 0.0699 0.0699
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Trypanosoma cruzi target of rapamycin kinase 3 0.0043 0.0077 0.0096
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0028 0.0041 0.0049
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0121 0.0269 0.0266
Entamoeba histolytica cysteine proteinase 1, putative 0.0014 0.0007 0.0004
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0016 0.0017
Schistosoma mansoni hypothetical protein 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Brugia malayi cytoplasmic intermediate filament protein 0.0048 0.009 0.0088
Echinococcus granulosus aldo keto reductase 0.0066 0.0134 0.0132
Loa Loa (eye worm) RNA binding protein 0.013 0.029 0.029
Brugia malayi chromobox protein homolog 3 0.0038 0.0065 0.0063
Schistosoma mansoni peroxidasin 0.0025 0.0034 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0063 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.009 0.0192 0.0192
Brugia malayi Histone deacetylase 1 0.0098 0.0211 0.0209
Schistosoma mansoni synaptojanin 0.0012 0.0003 0.0001
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0269 0.0263
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0589 0.1413 0.1413
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0007 0.0007
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Onchocerca volvulus 0.0219 0.0508 0.0505
Loa Loa (eye worm) hypothetical protein 0.0091 0.0194 0.0194
Echinococcus granulosus methionyl aminopeptidase 2 0.0188 0.0432 0.043
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0126 0.0125
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0269 0.0267
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0045 0.0043
Loa Loa (eye worm) beta-lactamase 0.0051 0.0097 0.0097
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.4097 1 1
Brugia malayi Bloom's syndrome protein homolog 0.003 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0187 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0036 0.006 0.0073
Schistosoma mansoni DNA polymerase eta 0.0076 0.0159 0.0157
Schistosoma mansoni histone deacetylase hda2 0.0053 0.0102 0.01
Mycobacterium tuberculosis Probable reductase 0.0238 0.0556 0.0553
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Toxoplasma gondii peptidase D, putative 0.0023 0.0029 0.0029
Trypanosoma cruzi cruzipain precursor, putative 0.0084 0.0178 0.0226
Echinococcus granulosus tm gpcr rhodopsin 0.0219 0.0508 0.0506
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0012 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Echinococcus multilocularis beta LACTamase domain containing family member 0.0051 0.0097 0.0095
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0027 0.004 0.004
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0028 0.004 0.0037
Schistosoma mansoni chromobox protein 0.0067 0.0137 0.0135
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0219 0.0508 0.0506
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0028 0.0041 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0126 0.0125
Echinococcus granulosus neuropeptide receptor 0.0219 0.0508 0.0506
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0048 0.0059
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0175 0.0402 0.0402
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0219 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0121 0.0269 0.0269
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.003 0.0028
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Echinococcus multilocularis roundabout 2 0.0027 0.0038 0.0036
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0012 0.0003 0.0003
Echinococcus multilocularis peroxidasin 0.0025 0.0034 0.0032
Echinococcus granulosus Down syndrome cell adhesion molecule 0.0027 0.0038 0.0036
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0036 0.006 0.0053
Leishmania major histone deacetylase, putative 0.0098 0.0211 0.0208
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0028 0.0041 0.0038
Schistosoma mansoni biogenic amine receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.002 0.0022 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus granulosus hypothetical protein 0.0219 0.0508 0.0506
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0188 0.0432 0.0432
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0051 0.0051
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0091 0.0194 0.0194
Echinococcus multilocularis Immunoglobulin 0.0025 0.0034 0.0032
Echinococcus granulosus Immunoglobulin 0.0025 0.0034 0.0032
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0087 0.0109
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0219 0.0508 0.0508
Echinococcus multilocularis Immunoglobulin 0.009 0.0193 0.0191
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Probable oxidoreductase 0.0066 0.0134 0.0131
Schistosoma mansoni pol-related 0.0066 0.0134 0.0132
Echinococcus granulosus cathepsin l cysteine peptidase 0.0028 0.004 0.0038
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Echinococcus granulosus Smad4 0.0017 0.0013 0.0011
Echinococcus multilocularis microtubule associated protein 2 0.0202 0.0468 0.0466
Plasmodium vivax FACT complex subunit SPT16, putative 0.0023 0.0029 0.0027
Toxoplasma gondii cytochrome p450 superfamily protein 0.0028 0.0041 0.0041
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0042 0.0074 0.0074
Mycobacterium tuberculosis Conserved hypothetical protein 0.0024 0.0031 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Schistosoma mansoni synaptojanin 0.0012 0.0003 0.0001
Toxoplasma gondii propionate-CoA ligase 0.0036 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0027 0.0038 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Schistosoma mansoni histone deacetylase hda2 0.0053 0.0102 0.01
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Trypanosoma brucei DNA polymerase eta, putative 0.0076 0.0159 0.0203
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Schistosoma mansoni neuropeptide receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Leishmania major DNA polymerase kappa, putative 0.0014 0.0007 0.0004
Trichomonas vaginalis Phospholipase C precursor, putative 0.0012 0.0003 0.0003
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0012 0.0003 0.0001
Brugia malayi nuclear hormone receptor family member nhr-6 0.003 0.0045 0.0043
Echinococcus multilocularis hemicentin 1 0.0025 0.0034 0.0032
Echinococcus multilocularis histone deacetylase 1 0.0098 0.0211 0.0209
Entamoeba histolytica 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0119 0.0264 0.0261
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0046 0.0085 0.0083
Brugia malayi Death domain containing protein 0.0017 0.0014 0.0012
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.0078 0.0163 0.0161
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0007 0.0006
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0188 0.0432 0.0432
Echinococcus granulosus nibrin 0.002 0.0022 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.004 0.0038
Leishmania major adenine aminohydrolase 0.4097 1 1
Plasmodium falciparum aminopeptidase P 0.0023 0.0029 0.0027
Plasmodium falciparum methionine aminopeptidase 1c, putative 0.0023 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0211 0.0489 0.0487
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0219 0.0508 0.0506
Plasmodium falciparum adenosine deaminase 0.4097 1 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0004
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.01 0.0097
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0104 0.0102
Plasmodium vivax aldehyde reductase, putative 0.0019 0.0019 0.0016
Schistosoma mansoni cpg binding protein 0.0098 0.0211 0.0209
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0091 0.0194 0.0191
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0029
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0014 0.0014
Chlamydia trachomatis endonuclease IV 0.0091 0.0196 0.1255
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0017 0.0015 0.0015
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0025 0.0034 0.0032
Trypanosoma cruzi cysteine proteinase, putative 0.0014 0.0007 0.0006
Leishmania major DNA damage repair protein, putative 0.0014 0.0007 0.0004
Toxoplasma gondii histone deacetylase HDAC4 0.0053 0.0102 0.0102
Schistosoma mansoni hypothetical protein 0.009 0.0193 0.0191
Mycobacterium tuberculosis Probable oxidoreductase 0.0265 0.0621 0.0618
Onchocerca volvulus 0.0018 0.0016 0.0014
Onchocerca volvulus 0.0219 0.0508 0.0505
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0058 0.0058
Echinococcus multilocularis neutral sphingomyelinase 0.0012 0.0003 0.0001
Echinococcus multilocularis dna polymerase kappa 0.0046 0.0085 0.0083
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.3172 0.7735 0.7734
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0025 0.0034 0.0032
Brugia malayi CHE-14 protein 0.0127 0.0284 0.0282
Brugia malayi Dopamine receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0115 0.0254 0.0254
Echinococcus granulosus lamin dm0 0.009 0.0192 0.019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni tar DNA-binding protein 0.013 0.029 0.0288
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0007 0.0004
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0016 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus multilocularis FACT complex subunit SPT16 0.0023 0.0029 0.0027
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Schistosoma mansoni hypothetical protein 0.0123 0.0273 0.0271
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0188 0.0432 0.0555
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0027 0.0038 0.0035
Loa Loa (eye worm) histone deacetylase 1 0.0098 0.0211 0.0211
Schistosoma mansoni chromosome transmission fidelity factor 0.002 0.0022 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Schistosoma mansoni titin 0.0025 0.0034 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.0063 0.0126 0.0125
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0028 0.0041 0.0034
Loa Loa (eye worm) patched family protein 0.0018 0.0016 0.0016
Brugia malayi Patched related family protein 10 0.0018 0.0016 0.0014
Leishmania major cytochrome p450-like protein 0.0028 0.0041 0.0038
Echinococcus granulosus Immunoglobulin 0.0025 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0028 0.0041 0.0038
Schistosoma mansoni DNA ligase IV 0.002 0.0022 0.002
Brugia malayi Immunoglobulin domain containing protein 0.0025 0.0034 0.0032
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0025 0.0034 0.0032
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.0027 0.0038 0.0036
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Brugia malayi G-protein coupled receptor 0.0219 0.0508 0.0506
Brugia malayi metallopeptidase family M24 containing protein 0.0023 0.0029 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Entamoeba histolytica cysteine proteinase 2 0.0014 0.0007 0.0004
Leishmania major hypothetical protein, conserved 0.1834 0.4462 0.446
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0002
Plasmodium vivax adenosine deaminase, putative 0.4097 1 1
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0097 0.021 0.0208
Mycobacterium ulcerans hypothetical protein 0.0019 0.0019 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0013
Schistosoma mansoni septate junction protein 0.0025 0.0034 0.0032
Onchocerca volvulus 0.0028 0.004 0.0037
Trypanosoma cruzi aminopeptidase P1, putative 0.0023 0.0029 0.0034
Schistosoma mansoni topbp1 0.002 0.0022 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0027 0.004 0.0048
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Leishmania major hypothetical protein, conserved 0.0038 0.0065 0.0062
Echinococcus multilocularis neuropeptide Y receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0027 0.0038 0.0038
Echinococcus granulosus neuropeptide Y receptor 0.0219 0.0508 0.0506
Brugia malayi AMP-binding enzyme family protein 0.0121 0.0269 0.0267
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0019 0.0019
Echinococcus granulosus voltage gated potassium channel 0.0016 0.0012 0.001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Trichomonas vaginalis penicillin-binding protein, putative 0.0051 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.006 0.0058
Echinococcus granulosus histone deacetylase 1 0.0098 0.0211 0.0209
Echinococcus granulosus serotonin receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0027 0.0038 0.0038
Loa Loa (eye worm) Smad1 0.0017 0.0013 0.0013
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0066 0.0134 0.0131
Plasmodium vivax proliferation-associated protein 2g4, putative 0.0023 0.0029 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0126 0.0125
Entamoeba histolytica AMP deaminase, putative 0.3172 0.7735 0.7734
Trichomonas vaginalis aldo/keto reductase, putative 0.0066 0.0134 0.0134
Plasmodium vivax DNA repair protein REV1, putative 0.0014 0.0007 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.005 0.005
Leishmania major methionine aminopeptidase 2, putative 0.0188 0.0432 0.0429
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus granulosus geminin 0.0373 0.0885 0.0883
Onchocerca volvulus 0.003 0.0045 0.0042
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0063 0.0126 0.0125
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0063 0.0126 0.0126
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0033 0.0054 0.0052
Loa Loa (eye worm) glutathione reductase 0.0104 0.0228 0.0228
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0219 0.0508 0.0506
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0036 0.0061 0.0058
Toxoplasma gondii ATPase, AAA family protein 0.002 0.0022 0.0022
Echinococcus multilocularis inositol monophosphatase 1 0.0027 0.004 0.0038
Onchocerca volvulus 0.0219 0.0508 0.0505
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0036 0.0034
Loa Loa (eye worm) independent phosphoglycerate mutase isoform 2 0.0119 0.0264 0.0264
Loa Loa (eye worm) cytochrome P450 family protein 0.0113 0.0249 0.0249
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0027 0.0038 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Echinococcus granulosus dna polymerase kappa 0.0046 0.0085 0.0083
Echinococcus multilocularis netrin receptor unc 5 0.0042 0.0076 0.0074
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0012 0.0002 0.0002
Entamoeba histolytica cysteine protease, putative 0.0028 0.004 0.0037
Brugia malayi conserved hypotetical protein 0.003 0.0045 0.0043
Onchocerca volvulus 0.0092 0.0198 0.0195
Plasmodium vivax acyl-CoA synthetase, putative 0.0091 0.0194 0.0191
Loa Loa (eye worm) hypothetical protein 0.4097 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0051 0.0097 0.009
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) immunoglobulin domain-containing protein 0.0025 0.0034 0.0034
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0012 0.0003 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0219 0.0508 0.0506
Toxoplasma gondii creatinase domain-containing protein 0.0023 0.0029 0.0029
Loa Loa (eye worm) CXXC zinc finger family protein 0.0092 0.0198 0.0198
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Echinococcus granulosus cathepsin l1 0.0019 0.0018 0.0016
Toxoplasma gondii target of rapamycin (TOR), putative 0.004 0.007 0.007
Schistosoma mansoni nuclear hormone receptor 0.003 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Schistosoma mansoni neuropeptide f receptor 76f 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0028 0.0041 0.0038
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0028 0.0041 0.0049
Echinococcus multilocularis histone deacetylase 3 0.0098 0.0211 0.0209
Echinococcus granulosus tissue type plasminogen activator 0.0038 0.0065 0.0063
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0018 0.0016 0.0017
Brugia malayi Cathepsin L-like precursor 0.0019 0.0018 0.0016
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.006 0.006
Trichomonas vaginalis D-aminoacylase, putative 0.0051 0.0097 0.0097
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0054 0.0052
Loa Loa (eye worm) hypothetical protein 0.0073 0.015 0.015
Echinococcus granulosus allatostatin A receptor 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.006 0.0057
Entamoeba histolytica aldose reductase, putative 0.0066 0.0134 0.0131
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0023 0.0029 0.0027
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0063 0.0126 0.0125
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0061 0.0075
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0012 0.0003 0.0003
Brugia malayi SET domain containing protein 0.0014 0.0006 0.0004
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0052 0.01 0.01
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0027 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.0091 0.0194 0.0194
Schistosoma mansoni adenoreceptor 0.0219 0.0508 0.0506
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Brugia malayi hypothetical protein 0.0018 0.0016 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Trypanosoma brucei RNA helicase, putative 0.162 0.3937 0.5088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0018 0.0018
Onchocerca volvulus 0.0023 0.0029 0.0027
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0023 0.0029 0.0034
Entamoeba histolytica AMP deaminase, putative 0.3172 0.7735 0.7734
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.4097 1 1
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0048 0.0048
Brugia malayi Nuclear hormone receptor-like 1 0.0063 0.0126 0.0125
Leishmania major trypanothione reductase 0.0104 0.0228 0.0225
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0019 0.0019 0.0017
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Brugia malayi Pre-SET motif family protein 0.0017 0.0015 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0036 0.0061 0.0075
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Brugia malayi Nuclear hormone receptor E75 0.003 0.0045 0.0043
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0219 0.0508 0.0506
Brugia malayi beta-lactamase family protein 0.0051 0.0097 0.0095
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Mycobacterium leprae putative cytochrome p450 0.0028 0.0041 0.0034
Onchocerca volvulus Methionine aminopeptidase 2 homolog 0.0188 0.0432 0.0429
Trypanosoma brucei AMP deaminase, putative 0.3172 0.7735 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0126 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Brugia malayi Cathepsin L-like precursor 0.0028 0.004 0.0038
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0066 0.0082
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0182 0.0179
Echinococcus multilocularis FTZ F1 alpha 0.0063 0.0126 0.0125
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0219 0.0508 0.0506
Entamoeba histolytica hypothetical protein 0.0116 0.0256 0.0253
Schistosoma mansoni DNA helicase recq1 0.0026 0.0036 0.0034
Schistosoma mansoni hypothetical protein 0.0062 0.0125 0.0123
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0028 0.0041 0.0034
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0054 0.0104 0.0101
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0125 0.0123
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Mycobacterium tuberculosis Conserved protein 0.0051 0.0097 0.0094
Schistosoma mansoni aminopeptidase P homologue (M24 family) 0.0023 0.0029 0.0027
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0188 0.0432 0.0432
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0052 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0025 0.0034 0.0034
Schistosoma mansoni netrin receptor unc5 0.0042 0.0076 0.0074
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0028 0.0041 0.0038
Schistosoma mansoni adenosine deaminase 0.4097 1 1
Brugia malayi intermediate filament protein 0.009 0.0192 0.019
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0028 0.0041 0.0034
Echinococcus granulosus smad 0.0017 0.0013 0.0011
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0033 0.0054 0.0052
Trypanosoma cruzi Metallopeptidase family M24, putative 0.0023 0.0029 0.0034
Brugia malayi Fibroblast growth factor family protein 0.0048 0.009 0.0088
Brugia malayi G protein-coupled receptor 0.0219 0.0508 0.0506
Plasmodium vivax SET domain protein, putative 0.0017 0.0015 0.0012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Loa Loa (eye worm) AMP deaminase 0.3172 0.7735 0.7735
Echinococcus multilocularis aldo keto reductase 0.0066 0.0134 0.0132
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.006 0.0057
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0017 0.0015 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0063 0.0126 0.0125
Echinococcus granulosus neuropeptides capa receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) histone deacetylase 11 0.0053 0.0102 0.0102
Echinococcus multilocularis AMP deaminase 2 0.3172 0.7735 0.7734
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0033 0.0054 0.0054
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0023 0.0029 0.0034
Schistosoma mansoni patched 1 0.0127 0.0284 0.0282
Echinococcus granulosus histone deacetylase 6 0.0053 0.0102 0.01
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0265 0.0621 0.0615
Brugia malayi AMP-binding enzyme family protein 0.0036 0.006 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0182 0.0179
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0028 0.0041 0.0038
Loa Loa (eye worm) neuropeptide F receptor 0.0219 0.0508 0.0508
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0028 0.0041 0.0034
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0019 0.0019
Leishmania major cytochrome p450-like protein 0.0038 0.0066 0.0063
Loa Loa (eye worm) G-protein coupled receptor 0.0219 0.0508 0.0508
Giardia lamblia Xaa-Pro dipeptidase 0.0023 0.0029 0.0402
Brugia malayi steroid hormone receptor 0.0063 0.0126 0.0125
Schistosoma mansoni DNA helicase recq5 0.0026 0.0036 0.0034
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0044 0.0044
Onchocerca volvulus 0.0066 0.0134 0.0131
Loa Loa (eye worm) hypothetical protein 0.0056 0.0109 0.0109
Schistosoma mansoni amine GPCR 0.0219 0.0508 0.0506
Brugia malayi Flap endonuclease-1 0.0031 0.0048 0.0046
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 32 0.0013 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus multilocularis g protein coupled receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0013 0.0004 0.0004
Schistosoma mansoni chromatin-specific transcription elongation factor 140 kDa subunit (M24 family) 0.0023 0.0029 0.0027
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0889 0.2148 0.2146
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0018 0.0016 0.0014
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0065 0.008
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0079 0.0099
Echinococcus multilocularis ecdysone induced protein 78C 0.0063 0.0126 0.0125
Echinococcus granulosus expressed conserved protein 0.0279 0.0655 0.0653
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0138 0.031 0.0307
Leishmania major pantothenate kinase subunit, putative 0.0017 0.0015 0.0012
Echinococcus granulosus hemicentin 1 0.0025 0.0034 0.0032
Brugia malayi basement membrane proteoglycan precursor 0.0025 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0027 0.004 0.0033
Echinococcus granulosus thioredoxin glutathione reductase 0.0104 0.0228 0.0226
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0219 0.0508 0.0506
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0028 0.0041 0.0034
Schistosoma mansoni cpg binding protein 0.0092 0.0198 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Schistosoma mansoni opsin-like receptor 0.0219 0.0508 0.0506
Toxoplasma gondii methionine aminopeptidase 0.0023 0.0029 0.0029
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.0455 0.0455
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0331 0.0329
Trichomonas vaginalis histone deacetylase, putative 0.0098 0.0211 0.0211
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0047 0.0088 0.0086
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0075
Echinococcus granulosus g protein coupled receptor 0.0219 0.0508 0.0506
Brugia malayi Nuclear hormone receptor-like 1 0.0033 0.0054 0.0052
Brugia malayi nuclear receptor NHR-88 0.003 0.0045 0.0043
Brugia malayi sulfakinin receptor protein 0.0219 0.0508 0.0506
Echinococcus granulosus ubiquitin specific protease 41 0.0047 0.0087 0.0085
Brugia malayi hypothetical protein 0.0116 0.0256 0.0254
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0269 0.0263
Echinococcus granulosus nuclear factor of activated T cells 5 0.0088 0.0187 0.0185
Schistosoma mansoni nuclear hormone receptor 0.003 0.0045 0.0043
Trypanosoma cruzi aldo/keto reductase, putative 0.0066 0.0134 0.017
Loa Loa (eye worm) inositol-1 0.0027 0.004 0.004
Brugia malayi tailless protein 0.003 0.0045 0.0043
Leishmania major cytochrome p450-like protein 0.0028 0.0041 0.0038
Brugia malayi Cytochrome P450 family protein 0.0028 0.0041 0.0039
Schistosoma mansoni aldo-keto reductase 0.0066 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.006 0.006
Mycobacterium leprae conserved hypothetical protein 0.0024 0.0031 0.0025
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Brugia malayi neuropeptide F receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Plasmodium vivax unspecified product 0.0014 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0062 0.0125 0.0125
Schistosoma mansoni cell adhesion molecule 0.0027 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.0078 0.0163 0.0163
Trypanosoma cruzi aldo/keto reductase, putative 0.0019 0.0019 0.0021
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1227 0.1227
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus granulosus voltage gated potassium channel subunit 0.0019 0.0019 0.0017
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.0663 0.0661
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0036 0.0061 0.0059
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Toxoplasma gondii transcriptional elongation factor FACT140 0.0023 0.0029 0.0029
Toxoplasma gondii aldose reductase, putative 0.0066 0.0134 0.0134
Leishmania major mitochondrial DNA polymerase beta 0.0311 0.0733 0.0731
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.036 0.0852 0.085
Mycobacterium leprae 3-dehydroquinate synthase AroB 0.0229 0.0533 0.0527
Echinococcus multilocularis thyroid hormone receptor alpha 0.0063 0.0126 0.0125
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0063 0.0126 0.0124
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Trichomonas vaginalis aldo/keto reductase, putative 0.0066 0.0134 0.0134
Toxoplasma gondii exonuclease III APE 0.0062 0.0123 0.0123
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0087 0.0085
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0097 0.021 0.021
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Leishmania major AMP deaminase, putative 0.3172 0.7735 0.7734
Onchocerca volvulus FACT complex subunit SPT16 homolog 0.0023 0.0029 0.0027
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0126 0.0125
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.003 0.0045 0.0043
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0219 0.0508 0.0506
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0014 0.0008 0.0008
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0036 0.006 0.0053
Loa Loa (eye worm) patched family protein 0.0018 0.0016 0.0016
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0018 0.0016 0.0014
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0269 0.0266
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0046 0.0085 0.0085
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0188 0.0432 0.0555
Schistosoma mansoni ap endonuclease 0.0062 0.0123 0.0121
Loa Loa (eye worm) initiation factor 2-associated protein 0.0188 0.0432 0.0432
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0126 0.0125
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0238 0.0556 0.0553
Echinococcus multilocularis lamin dm0 0.009 0.0192 0.019
Echinococcus multilocularis neuropeptide FF receptor 2 0.0219 0.0508 0.0506
Mycobacterium ulcerans hypothetical protein 0.0014 0.0007 0.0001
Loa Loa (eye worm) hypothetical protein 0.2263 0.5511 0.5511
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0018 0.0016 0.0017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0023 0.0023
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0119 0.0264 0.0338
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Onchocerca volvulus 0.0037 0.0062 0.0059
Mycobacterium tuberculosis Conserved hypothetical protein 0.0046 0.0085 0.0082
Mycobacterium tuberculosis Conserved protein 0.0051 0.0097 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0028 0.0041 0.0038
Echinococcus multilocularis xaa Pro dipeptidase 0.0023 0.0029 0.0027
Giardia lamblia Replication factor C, subunit 1 0.002 0.0022 0.0283
Echinococcus granulosus Proliferation associated protein 2G4 0.0023 0.0029 0.0027
Brugia malayi hypothetical protein 0.0018 0.0016 0.0014
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0167 0.0167
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.005 0.005
Loa Loa (eye worm) DR-78 0.003 0.0045 0.0045
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.4097 1 1
Onchocerca volvulus 0.0036 0.006 0.0057
Schistosoma mansoni hypothetical protein 0.0123 0.0273 0.0271
Onchocerca volvulus 0.0219 0.0508 0.0505
Brugia malayi ecdysone receptor 0.003 0.0045 0.0043
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Onchocerca volvulus 0.0121 0.0269 0.0266
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0054 0.0104 0.0101
Echinococcus multilocularis replication factor c subunit 1 0.002 0.0022 0.002
Echinococcus granulosus neuropeptide receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) nuclear receptor NHR-67 0.003 0.0045 0.0045
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0007 0.0004
Schistosoma mansoni hypothetical protein 0.0219 0.0508 0.0506
Echinococcus multilocularis aldo keto reductase 0.0066 0.0134 0.0132
Brugia malayi MH1 domain containing protein 0.0017 0.0013 0.0011
Brugia malayi hypothetical protein 0.003 0.0045 0.0043
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0051 0.0097 0.0095
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0097 0.021 0.0207
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Echinococcus granulosus roundabout 2 0.0027 0.0038 0.0036
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0028 0.0041 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0062 0.0123 0.0156
Echinococcus granulosus cathepsin L cysteine protease 0.0014 0.0007 0.0005
Brugia malayi ImpB/MucB/SamB family protein 0.0046 0.0085 0.0083
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0028 0.0041 0.0034
Schistosoma mansoni hypothetical protein 0.162 0.3937 0.3935
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0054 0.0104 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0065 0.0065
Schistosoma mansoni thyroid hormone receptor 0.0063 0.0126 0.0125
Trichomonas vaginalis ap endonuclease, putative 0.0062 0.0123 0.0123
Toxoplasma gondii methionine aminopeptidase, type i, putative 0.0023 0.0029 0.0029
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0018 0.0016 0.0014
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.0012 0.001
Onchocerca volvulus 0.0219 0.0508 0.0505
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Toxoplasma gondii kringle domain-containing protein 0.0038 0.0065 0.0065
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0219 0.0508 0.0506
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0007 0.0004
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0018 0.0016
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0072 0.0072
Echinococcus multilocularis neuroglian 0.0027 0.0038 0.0036
Brugia malayi AMP-binding enzyme family protein 0.0036 0.006 0.0058
Giardia lamblia Aldose reductase 0.0066 0.0134 0.1987
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0121 0.0269 0.0266
Echinococcus granulosus FACT complex subunit SPT16 0.0023 0.0029 0.0027
Mycobacterium tuberculosis Probable dehydrogenase 0.0238 0.0556 0.0553
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0026 0.0036 0.0034
Schistosoma mansoni growth hormone secretagogue receptor 0.0219 0.0508 0.0506
Echinococcus granulosus neuropeptides capa receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis methionine aminopeptidase, type I 0.0023 0.0029 0.0027
Schistosoma mansoni hypothetical protein 0.0373 0.0885 0.0883
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus granulosus cytochrome P450 2K1 0.0028 0.0041 0.0039
Entamoeba histolytica acyl-coA synthetase, putative 0.0121 0.0269 0.0266
Brugia malayi TAR-binding protein 0.013 0.029 0.0288
Echinococcus multilocularis dro:myosuppressin receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis traf and tnf receptor associated protein 0.0012 0.0003 0.0001
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0007 0.0006
Trypanosoma cruzi histone deacetylase 1, putative 0.0098 0.0211 0.0269
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0062 0.0123 0.0121
Echinococcus granulosus death domain containing protein 0.0017 0.0014 0.0012
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0036 0.0036
Mycobacterium ulcerans adenosine deaminase 0.4097 1 1
Echinococcus granulosus contactin 0.0027 0.0038 0.0036
Loa Loa (eye worm) histone deacetylase 0.0053 0.0102 0.0102
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0027 0.004 0.0048
Echinococcus granulosus low density lipoprotein receptor ldl 0.0025 0.0034 0.0032
Trypanosoma brucei DNA polymerase IV, putative 0.0046 0.0085 0.0106
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0097 0.021 0.021
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0003 0.0003
Echinococcus granulosus g-protein coupled receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis fmrfamide receptor 0.0219 0.0508 0.0506
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0036 0.0061 0.0059
Onchocerca volvulus 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypothetical protein 0.0091 0.0194 0.0194
Brugia malayi hypothetical protein 0.0018 0.0016 0.0014
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0012 0.0003 0.0001
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0103 0.0129
Loa Loa (eye worm) hypothetical protein 0.0017 0.0015 0.0015
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0016 0.0016
Echinococcus granulosus fmrfamide receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0062 0.0123 0.0121
Wolbachia endosymbiont of Brugia malayi phosphoglyceromutase 0.0119 0.0264 0.2919
Schistosoma mansoni proliferation-associated protein 2G4 38kDa (M24 family) 0.0023 0.0029 0.0027
Plasmodium falciparum proliferation-associated protein 2g4, putative 0.0023 0.0029 0.0027
Mycobacterium tuberculosis Probable lipase LipE 0.0051 0.0097 0.0094
Onchocerca volvulus 0.009 0.0192 0.0189
Echinococcus multilocularis deoxyribonuclease 1 2 0.0012 0.0003 0.0001
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0027 0.0038 0.0045
Echinococcus multilocularis roundabout 2 0.0027 0.0038 0.0036
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Mycobacterium tuberculosis Conserved protein 0.0051 0.0097 0.0094
Brugia malayi CHD4 protein 0.0016 0.0012 0.001
Echinococcus multilocularis Niemann Pick C1 protein 0.0424 0.1011 0.1009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0104 0.0104
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.004 0.0037
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0028 0.0041 0.0038
Plasmodium falciparum thioredoxin reductase 0.0036 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.1834 0.4462 0.4462
Mycobacterium leprae Possible oxidoreductase 0.0019 0.0019 0.0013
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0282 0.0663 0.0661
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.003 0.0045 0.0043
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Onchocerca volvulus 0.0019 0.0018 0.0015
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0023 0.0029 0.0027
Mycobacterium ulcerans acetyl-CoA synthetase 0.0036 0.006 0.0053
Leishmania major cathepsin L-like protease 0.0084 0.0178 0.0175
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0016 0.0012 0.001
Echinococcus multilocularis methionyl aminopeptidase 1 (M24 family) 0.0023 0.0029 0.0027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0331 0.0329
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0015 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0022
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0062 0.0123 0.0121
Echinococcus multilocularis Two pore potassium channel protein sup 9 0.0187 0.0429 0.0427
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.002 0.0022 0.0022
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0063 0.0126 0.0125
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.005 0.005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0104 0.0104
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0027 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0048 0.009 0.009
Brugia malayi Patched related family protein 12 0.0018 0.0016 0.0014
Loa Loa (eye worm) hypoxia-induced factor 1 0.0086 0.0183 0.0183
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0036 0.006 0.0053
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0045 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0006 0.0004
Loa Loa (eye worm) thioredoxin reductase 0.0104 0.0228 0.0228
Giardia lamblia 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0119 0.0264 0.3954
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0167 0.016
Schistosoma mansoni microtubule-associated protein tau 0.0202 0.0468 0.0466
Trichomonas vaginalis aldo/keto reductase, putative 0.0066 0.0134 0.0134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Loa Loa (eye worm) oxidoreductase 0.0066 0.0134 0.0134
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.006 0.0073
Loa Loa (eye worm) methionine aminopeptidase type I 0.0023 0.0029 0.0029
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Schistosoma mansoni lamin 0.009 0.0192 0.019
Plasmodium falciparum cysteine proteinase falcipain 3 0.0028 0.004 0.0037
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0048 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0007 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0219 0.0508 0.0506
Schistosoma mansoni lamin 0.009 0.0192 0.019
Plasmodium vivax vivapain-2 0.0028 0.004 0.0037
Onchocerca volvulus 0.0028 0.004 0.0037
Echinococcus multilocularis G-protein coupled receptor, putative 0.0219 0.0508 0.0506
Entamoeba histolytica deoxycytidyl transferase, putative 0.0046 0.0085 0.0082
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0138 0.031 0.0304
Schistosoma mansoni roundabout 0.0025 0.0034 0.0032
Trypanosoma brucei methionine aminopeptidase 2, putative 0.0188 0.0432 0.0555
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus granulosus sterol regulatory element binding protein 0.0127 0.0284 0.0282
Brugia malayi exodeoxyribonuclease III family protein 0.0062 0.0123 0.0121
Echinococcus multilocularis tissue type plasminogen activator 0.0038 0.0065 0.0063
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Echinococcus multilocularis chromobox protein 1 0.0067 0.0137 0.0135
Brugia malayi Melatonin receptor type 1A 0.0219 0.0508 0.0506
Echinococcus granulosus 7tm_1 domain containing protein 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Loa Loa (eye worm) oxidoreductase 0.0066 0.0134 0.0134
Echinococcus granulosus Two pore potassium channel protein sup 9 0.0187 0.0429 0.0427
Trypanosoma cruzi AMP deaminase, putative 0.3172 0.7735 1
Trichomonas vaginalis glutathione reductase, putative 0.0036 0.0061 0.0061
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0007 0.0006
Schistosoma mansoni histamine h1 receptor 0.0219 0.0508 0.0506
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0027 0.004 0.0217
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0028 0.0041 0.0034
Trichomonas vaginalis histone deacetylase, putative 0.0098 0.0211 0.0211
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0311 0.0733 0.0945
Plasmodium vivax vivapain-2 0.0028 0.004 0.0037
Brugia malayi Heparan sulfate 0.0025 0.0034 0.0032
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0027 0.0038 0.0036
Echinococcus multilocularis serotonin receptor 0.0219 0.0508 0.0506
Echinococcus granulosus dro:myosuppressin receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis Immunoglobulin subtype 0.0025 0.0034 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Onchocerca volvulus 0.0219 0.0508 0.0505
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0018 0.0016 0.0014
Brugia malayi larval opioid receptor 0.0219 0.0508 0.0506
Mycobacterium leprae conserved hypothetical protein 0.0051 0.0097 0.009
Onchocerca volvulus 0.0018 0.0016 0.0014
Schistosoma mansoni basigin related 0.0025 0.0034 0.0032
Leishmania major hypothetical protein, conserved 0.0023 0.0029 0.0027
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.4097 1 1
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0054 0.0104 0.0102
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0029
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0108 0.0237 0.0237
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.002 0.0022 0.0022
Echinococcus granulosus FTZ F1 alpha 0.0063 0.0126 0.0125
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0062 0.0123 0.0121
Brugia malayi cytochrome P450 0.0028 0.0041 0.0039
Echinococcus granulosus somatostatin receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0513 0.1227 0.1227
Schistosoma mansoni nuclear hormone receptor 0.0063 0.0126 0.0125
Plasmodium vivax methionine aminopeptidase 1a, putative 0.0023 0.0029 0.0027
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0036 0.0061 0.0474
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Echinococcus granulosus hypothetical protein 0.0066 0.0134 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0091 0.0194 0.0194
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0027 0.004 0.0037
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.0027 0.0038 0.0036
Onchocerca volvulus 0.0018 0.0016 0.0014
Trichomonas vaginalis D-aminoacylase, putative 0.0051 0.0097 0.0097
Brugia malayi AMP-binding enzyme family protein 0.0036 0.006 0.0058
Echinococcus multilocularis tyrosine protein kinase otk 0.0025 0.0034 0.0032
Echinococcus multilocularis Xaa Pro aminopeptidase 3 0.0023 0.0029 0.0027
Brugia malayi Cathepsin L-like precursor 0.0028 0.004 0.0038
Leishmania major cathepsin L-like protease 0.0028 0.004 0.0037
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0027
Entamoeba histolytica 2,3-bisphosphoglycerate-independentphosphoglycerate mutase, putative 0.0066 0.0133 0.013
Echinococcus granulosus peroxidasin 0.0025 0.0034 0.0032
Trypanosoma cruzi cysteine proteinase, putative 0.0014 0.0007 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.084 0.084
Onchocerca volvulus 0.0123 0.0273 0.027
Echinococcus granulosus Niemann Pick C1 protein 0.0424 0.1011 0.1009
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0036 0.006 0.0057
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni neuropeptide receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0027 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Plasmodium falciparum histone deacetylase, putative 0.0053 0.0102 0.01
Brugia malayi Cytochrome P450 family protein 0.0113 0.0249 0.0247
Echinococcus granulosus roundabout 2 0.0027 0.0038 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Leishmania major hypothetical protein, conserved 0.0056 0.0109 0.0106
Mycobacterium ulcerans lipase LipD 0.0051 0.0097 0.009
Mycobacterium leprae Probable cytoplasmic peptidase PepQ 0.0023 0.0029 0.0023
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0016 0.0012 0.001
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0022 0.0024
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0087 0.0109
Toxoplasma gondii histone lysine methyltransferase SET1 0.0175 0.0402 0.0402
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0072 0.0072
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0007 0.0006
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0044 0.0079 0.0099
Leishmania major cathepsin L-like protease 0.0028 0.004 0.0037
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0084 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0036 0.006 0.0053
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0016 0.0014
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0012 0.0009
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0003 0.0003
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0063 0.0126 0.0125
Schistosoma mansoni methionyl aminopeptidase 2 (M24 family) 0.0188 0.0432 0.043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0077 0.0077
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0047 0.0087 0.0085
Schistosoma mansoni smad1 5 8 and 0.0017 0.0013 0.0011
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Leishmania major 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like 0.0019 0.002 0.0017
Echinococcus granulosus dnaJ subfamily B 0.0488 0.1167 0.1165
Leishmania major histone deacetylase, putative 0.0053 0.0102 0.01
Onchocerca volvulus Cathepsin F homolog 0.0028 0.004 0.0037
Onchocerca volvulus 0.0038 0.0065 0.0062
Giardia lamblia GTOR 0.0054 0.0104 0.1525
Loa Loa (eye worm) hypothetical protein 0.0066 0.0134 0.0134
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0062 0.0123 0.1826
Toxoplasma gondii histone deacetylase HDAC3 0.0098 0.0211 0.0211
Schistosoma mansoni neuropeptide receptor 0.0219 0.0508 0.0506
Echinococcus granulosus Xaa Pro aminopeptidase 3 0.0023 0.0029 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0022
Schistosoma mansoni myosin xvIII 0.0219 0.0508 0.0506
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0219 0.0508 0.0506
Brugia malayi nuclear receptor NHR-67 0.003 0.0045 0.0043
Echinococcus multilocularis Nuclear hormone receptor HR96 0.003 0.0045 0.0043
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0164 0.0373 0.037
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0062 0.0123 0.0121
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.0455 0.0454
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.036 0.0852 1
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0042 0.0074 0.0074
Echinococcus granulosus xaa Pro dipeptidase 0.0023 0.0029 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0051 0.0097 0.0094
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0012 0.0003 0.0003
Schistosoma mansoni adenosine deaminase-related 0.4097 1 1
Schistosoma mansoni twik family of potassium channels-related 0.0187 0.0429 0.0427
Trichomonas vaginalis DNA polymerase eta, putative 0.0046 0.0085 0.0085
Loa Loa (eye worm) oxidoreductase 0.0036 0.006 0.006
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0077 0.0077
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0028 0.0041 0.0038
Mycobacterium tuberculosis 3-dehydroquinate synthase AroB 0.0229 0.0533 0.0531
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.2263 0.5511 0.5511
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0062 0.0123 0.0121
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.0733 0.0945
Schistosoma mansoni smad1 5 8 and 0.0017 0.0013 0.0011
Mycobacterium ulcerans putative regulatory protein 0.0021 0.0023 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0063 0.0126 0.0125
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.0164
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.0164
Brugia malayi ORL1-like opioid receptor 0.0219 0.0508 0.0506
Brugia malayi beta-lactamase family protein 0.0051 0.0097 0.0095
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0097 0.021 0.0207
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Brugia malayi CCR4 0.0012 0.0003 0.0001
Echinococcus granulosus histone deacetylase 3 0.0098 0.0211 0.0209
Echinococcus multilocularis cathepsin L cysteine protease 0.0028 0.004 0.0038
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0004 0.0001
Brugia malayi ecdysteroid receptor 0.0063 0.0126 0.0125
Entamoeba histolytica hypothetical protein 0.0116 0.0256 0.0253
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0024 0.0031 0.0025
Echinococcus granulosus neutral sphingomyelinase 0.0012 0.0003 0.0001
Schistosoma mansoni hypothetical protein 0.009 0.0193 0.0191
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.006 0.0057
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0097 0.021 0.0208
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0027 0.0027
Brugia malayi Cathepsin L-like precursor 0.0028 0.004 0.0038
Brugia malayi Cytochrome P450 family protein 0.0038 0.0066 0.0064
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0265 0.0621 0.0618
Brugia malayi Nuclear hormone receptor E75 0.003 0.0045 0.0043
Mycobacterium tuberculosis Conserved protein 0.0019 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Brugia malayi histone deacetylase 11 0.0053 0.0102 0.01
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.003 0.0045 0.0042
Trypanosoma brucei aldo/keto reductase, putative 0.0019 0.0019 0.0021
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0038 0.0065 0.0062
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0014 0.0007 0.0005
Trypanosoma brucei trypanothione reductase 0.0104 0.0228 0.0291
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0219 0.0508 0.0506
Schistosoma mansoni cpg binding protein 0.0098 0.0211 0.0209
Schistosoma mansoni smad 0.0017 0.0013 0.0011
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.016
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0028 0.0041 0.0034
Trypanosoma cruzi cysteine peptidase, putative 0.0084 0.0178 0.0226
Echinococcus multilocularis chromobox protein 1 0.0067 0.0137 0.0135
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.006 0.0053
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0045 0.0082 0.0082
Brugia malayi hypothetical protein 0.0018 0.0016 0.0014
Echinococcus granulosus neuropeptide s receptor 0.0768 0.1852 0.185
Trypanosoma brucei histone deacetylase 2 0.0053 0.0102 0.0129
Echinococcus granulosus aldehyde reductase 0.0047 0.0087 0.0085
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.0012 0.001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0063 0.0126 0.0126
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Trichomonas vaginalis DNA helicase recq, putative 0.003 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Brugia malayi Uncoordinated protein 44 0.0017 0.0014 0.0012
Brugia malayi RNA binding protein 0.013 0.029 0.0288
Schistosoma mansoni amine GPCR 0.0219 0.0508 0.0506
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0091 0.0196 0.0194
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Brugia malayi Prion-like- 0.0025 0.0034 0.0032
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.3172 0.7735 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0047 0.0088 0.0088
Brugia malayi metallopeptidase family M24 containing protein 0.0023 0.0029 0.0027
Onchocerca volvulus 0.0066 0.0134 0.0131
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0019 0.0019 0.0016
Leishmania major cathepsin L-like protease 0.0028 0.004 0.0037
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0019 0.0019 0.0019
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0047 0.0087 0.128
Onchocerca volvulus 0.1834 0.4462 0.446
Toxoplasma gondii thioredoxin reductase 0.0104 0.0228 0.0228
Loa Loa (eye worm) cysteine protease 0.0028 0.004 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0182 0.0179
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0063 0.0126 0.0125
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0062 0.0123 0.0156
Mycobacterium ulcerans 2-nitropropane dioxygenase 0.0028 0.004 0.0034
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.1337 0.3246 0.3246
Echinococcus granulosus xaa Pro dipeptidase 0.0023 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.006 0.006
Brugia malayi basement membrane proteoglycan 0.0025 0.0034 0.0032
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0219 0.0508 0.0506
Trypanosoma brucei histone deacetylase 1 0.0098 0.0211 0.0269
Onchocerca volvulus 0.0021 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0018
Echinococcus multilocularis cysteine protease 0.0028 0.004 0.0038
Brugia malayi bHLH-PAS transcription factor 0.0021 0.0023 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0091 0.0196 0.0193
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Onchocerca volvulus 0.003 0.0045 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0098 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Mycobacterium ulcerans 3-dehydroquinate synthase 0.0229 0.0533 0.0527
Brugia malayi protein C24B5.3 0.0018 0.0016 0.0014
Loa Loa (eye worm) DNA-binding protein 0.0023 0.0029 0.0029
Entamoeba histolytica aldose reductase, putative 0.0066 0.0134 0.0131
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0238 0.0556 0.0553
Mycobacterium tuberculosis Dipeptidase PepE 0.0023 0.0029 0.0027
Trypanosoma brucei histone deacetylase, putative 0.0053 0.0102 0.0129
Loa Loa (eye worm) hypothetical protein 0.0346 0.0819 0.0819
Mycobacterium ulcerans hypothetical protein 0.0051 0.0097 0.009
Mycobacterium ulcerans DNA polymerase IV 0.0046 0.0085 0.0079
Plasmodium vivax peptidase, putative 0.0023 0.0029 0.0027
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0049 0.0092 0.009
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Echinococcus granulosus irregular chiasm roughest protein 0.009 0.0193 0.0191
Plasmodium vivax ataxin-2 like protein, putative 0.0056 0.0109 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0028 0.004 0.004
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0019 0.0019 0.0019
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.009 0.0192 0.0192
Onchocerca volvulus 0.0025 0.0034 0.0031
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Loa Loa (eye worm) intermediate filament protein 0.009 0.0192 0.0192
Toxoplasma gondii AMP deaminase 0.3172 0.7735 0.7735
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0028 0.0041 0.0034
Echinococcus granulosus traf and tnf receptor associated protein 0.0012 0.0003 0.0001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0063 0.0126 0.0125
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0269 0.0266
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.3172 0.7735 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0219 0.0508 0.0506
Schistosoma mansoni neuropeptide F-like receptor 0.0219 0.0508 0.0506
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0025 0.0033 0.0031
Trypanosoma cruzi Metallopeptidase family M24/FACT complex subunit (SPT16/CDC68)/Histone chaperone Rttp106-like, putative 0.0023 0.0029 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Echinococcus multilocularis roundabout 2 0.0027 0.0038 0.0036
Leishmania major cysteine peptidase A (CPA) 0.0028 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Trypanosoma brucei hypothetical protein, conserved 0.0051 0.0097 0.0121
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0134 0.0132
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0028 0.0041 0.0034
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0036 0.0061 0.0058
Brugia malayi Twik (KCNK-like) family of potassium channels, alpha subunit 30. 0.0013 0.0004 0.0001
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0013 0.0011
Plasmodium vivax acetyl-CoA synthetase, putative 0.0036 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Onchocerca volvulus 0.0018 0.0016 0.0014
Entamoeba histolytica hypothetical protein, conserved 0.0023 0.0029 0.0027
Plasmodium vivax vivapain-3 0.0014 0.0007 0.0004
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0097
Onchocerca volvulus Dipeptidase C homolog 0.0023 0.0029 0.0027
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.0331 0.0329
Chlamydia trachomatis methionine aminopeptidase 0.0023 0.0029 0.0057
Echinococcus granulosus survival motor neuron protein 1 0.0124 0.0276 0.0274
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0063 0.0126 0.0125
Onchocerca volvulus Protein patched homolog 0.0018 0.0016 0.0014
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0039 0.0036
Onchocerca volvulus Adenosine deaminase homolog 0.4097 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0036 0.0034
Mycobacterium ulcerans hypothetical protein 0.0028 0.004 0.0034
Plasmodium vivax thioredoxin reductase, putative 0.0104 0.0228 0.0225
Brugia malayi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 0.0073 0.0151 0.0149
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Brugia malayi CXXC zinc finger family protein 0.0092 0.0198 0.0196
Echinococcus multilocularis nephrin 0.009 0.0193 0.0191
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0219 0.0508 0.0505
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0036 0.0061 0.0061
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0066 0.0134 0.0134
Onchocerca volvulus 0.0066 0.0134 0.0131
Loa Loa (eye worm) hypothetical protein 0.0017 0.0014 0.0014
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0012 0.001
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Schistosoma mansoni Xaa-Pro dipeptidase (M24 family) 0.0023 0.0029 0.0027
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0063 0.0126 0.0125
Loa Loa (eye worm) follicle stimulating hormone receptor 0.072 0.1735 0.1735
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0014 0.0014
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0007 0.0005
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0025 0.0033 0.0026
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0029 0.0043 0.0037
Trypanosoma brucei unspecified product 0.0046 0.0085 0.0106
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0125 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0013 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0219 0.0508 0.0506
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.006 0.0073
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0019 0.0019
Schistosoma mansoni opsin-like receptor 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0325 0.0767 0.0764
Trypanosoma cruzi AMP deaminase, putative 0.3172 0.7735 1
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0028 0.0041 0.0038
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.006 0.0057
Echinococcus granulosus g protein coupled receptor 0.0219 0.0508 0.0506
Echinococcus granulosus lamin 0.009 0.0192 0.019
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Trypanosoma cruzi aldo-keto reductase 0.0066 0.0134 0.017
Schistosoma mansoni hypothetical protein 0.0062 0.0125 0.0123
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.3172 0.7735 0.7734
Echinococcus granulosus histone deacetylase 0.0053 0.0102 0.01
Toxoplasma gondii aldo-keto reductase 0.0019 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Plasmodium vivax vivapain-1 0.0014 0.0007 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0097
Brugia malayi Immunoglobulin I-set domain containing protein 0.0027 0.0038 0.0036
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0051 0.0097 0.0095
Leishmania major enoyl-[acyl-carrier-protein] reductase, putative 0.0028 0.004 0.0037
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0003 0.0001
Schistosoma mansoni tyrosine kinase 0.0025 0.0034 0.0032
Schistosoma mansoni nephrin 0.0027 0.0038 0.0036
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0003 0.0003
Schistosoma mansoni cript-related 0.0012 0.0003 0.0001
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0046 0.0085 0.0082
Onchocerca volvulus 0.0219 0.0508 0.0505
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0125 0.0123
Trichomonas vaginalis histone deacetylase, putative 0.0098 0.0211 0.0211
Schistosoma mansoni neuropeptide F-like receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0025 0.0034 0.0032
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0029 0.0043 0.004
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0019 0.002 0.0022
Plasmodium vivax hypothetical protein, conserved 0.0051 0.0097 0.0094
Schistosoma mansoni septate junction protein 0.0025 0.0034 0.0032
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0092 0.009
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0054 0.0104 0.0102
Schistosoma mansoni amine GPCR 0.0219 0.0508 0.0506
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Giardia lamblia Flap structure-specific endonuclease 0.0031 0.0048 0.0689
Echinococcus multilocularis Immunoglobulin 0.0025 0.0034 0.0032
Trypanosoma cruzi AMP deaminase, putative 0.3172 0.7735 1
Brugia malayi Immunoglobulin domain containing protein 0.0025 0.0034 0.0032
Brugia malayi metallopeptidase family M24 containing protein 0.0023 0.0029 0.0027
Echinococcus multilocularis protein patched 0.0127 0.0284 0.0282
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0134 0.0132
Loa Loa (eye worm) hypothetical protein 0.0023 0.0029 0.0029
Brugia malayi hypothetical protein 0.0033 0.0054 0.0052
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0024 0.0031 0.0028
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0025 0.0034 0.0041
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0022
Onchocerca volvulus 0.0066 0.0134 0.0131
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0219 0.0508 0.0506
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0167 0.0165
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.006 0.0057
Onchocerca volvulus 0.0219 0.0508 0.0505
Mycobacterium ulcerans cytoplasmic peptidase PepQ 0.0023 0.0029 0.0023
Schistosoma mansoni hypothetical protein 0.0135 0.0303 0.0301
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.1044
Echinococcus granulosus G protein coupled receptor 139 0.0219 0.0508 0.0506
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0046 0.0085 0.0085
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0091 0.0196 0.0193
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Leishmania major hypothetical protein, conserved 0.0051 0.0097 0.0094
Plasmodium falciparum methionine aminopeptidase 1b, putative 0.0023 0.0029 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Loa Loa (eye worm) histone deacetylase 3 0.0098 0.0211 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0051 0.0051
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.0019 0.0016
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0097 0.021 0.021
Onchocerca volvulus 0.0018 0.0016 0.0014
Echinococcus granulosus g protein coupled receptor 0.0219 0.0508 0.0506
Schistosoma mansoni chromobox protein 0.0067 0.0137 0.0135
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Brugia malayi initiation factor 2-associated protein. 0.0188 0.0432 0.043
Echinococcus granulosus adenosine deaminase 0.4097 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.002 0.0022 0.002
Echinococcus granulosus cathepsin L cysteine proteinase 0.0028 0.004 0.0038
Echinococcus multilocularis neuropeptide Y receptor 0.0219 0.0508 0.0506
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0075 0.0155 0.0197
Trypanosoma cruzi AMP deaminase 2, putative 0.1834 0.4462 0.5767
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0026 0.0036 0.0036
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.1748
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0063 0.0126 0.0126
Schistosoma mansoni coup transcription factor 0.0063 0.0126 0.0125
Echinococcus granulosus pro neuregulin 2 membrane bound 0.0025 0.0034 0.0032
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0238 0.0556 0.0549
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.006
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0097 0.021 0.0207
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0066 0.0134 0.0134
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0007
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.0026 0.0036 0.0036
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0028 0.004 0.004
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0028 0.0041 0.0039
Brugia malayi hypothetical protein 0.0124 0.0276 0.0274
Mycobacterium ulcerans dipeptidase PepE 0.0023 0.0029 0.0023
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Onchocerca volvulus 0.0219 0.0508 0.0505
Schistosoma mansoni hypothetical protein 0.0116 0.0256 0.0254
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Plasmodium falciparum AMP deaminase, putative 0.3172 0.7735 0.7734
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Mycobacterium ulcerans hypothetical protein 0.0024 0.0031 0.0025
Echinococcus multilocularis histone deacetylase 6 0.0053 0.0102 0.01
Brugia malayi DNA-binding protein, 42 kDa containing protein 0.0023 0.0029 0.0027
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.006 0.0053
Brugia malayi Thioredoxin reductase 0.0104 0.0228 0.0226
Toxoplasma gondii patched family protein 0.0018 0.0016 0.0016
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0015 0.0013
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0104 0.0104
Plasmodium falciparum cysteine proteinase falcipain 1 0.0014 0.0007 0.0004
Mycobacterium tuberculosis Probable esterase LipL 0.0051 0.0097 0.0094
Plasmodium vivax adenosine/AMP deaminase, putative 0.3172 0.7735 0.7734
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0013 0.0011
Echinococcus granulosus cysteine protease 0.0014 0.0007 0.0005
Onchocerca volvulus 0.0051 0.0097 0.0094
Trichomonas vaginalis chromobox protein, putative 0.0067 0.0137 0.0137
Toxoplasma gondii LsmAD domain-containing protein 0.0056 0.0109 0.0109
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0013 0.0011
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0027 0.004 0.0037
Entamoeba histolytica cysteine proteinase, putative 0.0014 0.0007 0.0004
Brugia malayi Immunoglobulin I-set domain containing protein 0.0115 0.0254 0.0253
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Treponema pallidum ATP-dependent DNA helicase 0.0013 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0097
Treponema pallidum DNA ligase (lig) 0.002 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0028 0.0041 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0061 0.0122 0.0154
Toxoplasma gondii proliferation-associated protein 2G4, putative 0.0023 0.0029 0.0029
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0025 0.0033 0.0031
Echinococcus granulosus AMP deaminase 2 0.3172 0.7735 0.7734
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) histone deacetylase 7A 0.0053 0.0102 0.0102
Brugia malayi G protein-coupled receptor F59B2.13 0.0219 0.0508 0.0506
Echinococcus multilocularis dna polymerase eta 0.0076 0.0159 0.0157
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.005 0.0061
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0036 0.0061 0.0058
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0097
Trichomonas vaginalis glucosylceramidase, putative 0.0336 0.0795 0.0795
Echinococcus granulosus nephrin 0.009 0.0193 0.0191
Echinococcus multilocularis aldo keto reductase 0.0066 0.0134 0.0132
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0219 0.0508 0.0506
Schistosoma mansoni hypothetical protein 0.0219 0.0508 0.0506
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0063 0.0126 0.0125
Trichomonas vaginalis 2-nitropropane dioxygenase precursor, putative 0.0028 0.004 0.004
Trichomonas vaginalis ap endonuclease, putative 0.0062 0.0123 0.0123
Schistosoma mansoni septate junction protein 0.0025 0.0034 0.0032
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0027 0.0038 0.0036
Toxoplasma gondii NADPH-glutathione reductase 0.0036 0.0061 0.0061
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0332 0.033
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.001 0.001
Echinococcus multilocularis voltage gated potassium channel subunit 0.0019 0.0019 0.0017
Brugia malayi glutathione reductase 0.0104 0.0228 0.0226
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0027 0.0038 0.0036
Entamoeba histolytica recQ family DNA helicase 0.0013 0.0005 0.0002
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0026 0.0036 0.0034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0063 0.0126 0.0125
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.0027 0.0038 0.0035
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Trypanosoma brucei chrX additional, unordered contigs 0.0014 0.0007 0.0006
Loa Loa (eye worm) nuclear receptor nhr-7B 0.003 0.0045 0.0045
Brugia malayi hypothetical protein 0.0036 0.006 0.0058
Toxoplasma gondii endonuclease IV APN 0.0091 0.0196 0.0196
Onchocerca volvulus Neuropeptide F receptor homolog 0.0219 0.0508 0.0505
Brugia malayi Immunoglobulin domain containing protein 0.0025 0.0034 0.0032
Mycobacterium ulcerans endonuclease IV 0.0091 0.0196 0.019
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0025 0.0034 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1227 0.1227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0282 0.0663 0.0663
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.006 0.0057
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0036 0.0061 0.0283
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0014 0.0007 0.0006
Brugia malayi Papain family cysteine protease containing protein 0.0028 0.004 0.0038
Schistosoma mansoni biogenic amine receptor 0.0219 0.0508 0.0506
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0097 0.021 0.0208
Loa Loa (eye worm) patched family protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Schistosoma mansoni hypothetical protein 0.0062 0.0125 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Entamoeba histolytica histone deacetylase, putative 0.0098 0.0211 0.0208
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0028 0.0041 0.0038
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0063 0.0126 0.0125
Brugia malayi Heterochromatin protein 1 0.0067 0.0137 0.0135
Loa Loa (eye worm) LAD-2 short isoform 0.0025 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.002 0.0022 0.0022
Schistosoma mansoni hypothetical protein 0.0373 0.0885 0.0883
Loa Loa (eye worm) hypothetical protein 0.0012 0.0002 0.0002
Mycobacterium tuberculosis Methionine aminopeptidase MapB (map) (peptidase M) 0.0023 0.0029 0.0027
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.006 0.006
Onchocerca volvulus 0.0028 0.004 0.0037
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0027 0.0038 0.0036
Brugia malayi Serotonin receptor 0.0219 0.0508 0.0506
Plasmodium falciparum histone deacetylase 1 0.0098 0.0211 0.0208
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0066 0.0134 0.0134
Toxoplasma gondii cathepsin CPL 0.0028 0.004 0.004
Onchocerca volvulus Protein ultraspiracle homolog 0.0063 0.0126 0.0124
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0026 0.0036 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Treponema pallidum methionine aminopeptidase (map) 0.0023 0.0029 0.0027
Echinococcus multilocularis xaa pro aminopeptidase 0.0023 0.0029 0.0027
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0039 0.0036
Leishmania major methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0027
Treponema pallidum adenosine deaminase 0.4097 1 1
Brugia malayi Pre-SET motif family protein 0.0108 0.0237 0.0235
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0119 0.0264 0.0338
Mycobacterium ulcerans aminopeptidase 0.0023 0.0029 0.0023
Trypanosoma cruzi histone deacetylase, putative 0.0053 0.0102 0.0129
Treponema pallidum fructose-bisphosphate aldolase 0.0282 0.0663 0.0661
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Schistosoma mansoni basigin related 0.0025 0.0034 0.0032
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0007 0.0006
Loa Loa (eye worm) oxidoreductase 0.0066 0.0134 0.0134
Wolbachia endosymbiont of Brugia malayi trans-2-enoyl-ACP reductase, FabK 0.0028 0.004 0.0226
Leishmania major histone deacetylase, putative 0.0053 0.0102 0.01
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0589 0.1413 0.1408
Plasmodium falciparum methionine aminopeptidase 2 0.0188 0.0432 0.0429
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0066 0.0134 0.0132
Plasmodium falciparum thioredoxin reductase 0.0104 0.0228 0.0225
Schistosoma mansoni peptidase 0.0023 0.0029 0.0027
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0121 0.0269 0.0263
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0018 0.0016 0.0017
Onchocerca volvulus Cathepsin L homolog 0.0028 0.004 0.0037
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0036 0.006 0.0053
Echinococcus multilocularis somatostatin receptor 0.0219 0.0508 0.0506
Onchocerca volvulus 0.0219 0.0508 0.0505
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0007 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0047 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Onchocerca volvulus 0.0066 0.0134 0.0131
Echinococcus granulosus synaptojanin 1 0.0012 0.0003 0.0001
Brugia malayi histone deacetylase 1 (HD1) 0.0098 0.0211 0.0209
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Mycobacterium ulcerans methionine aminopeptidase MapB 0.0023 0.0029 0.0023
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0219 0.0508 0.0506
Trypanosoma brucei PAB1-binding protein , putative 0.0056 0.0109 0.0137
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1227 0.1227
Plasmodium falciparum glutathione reductase 0.0036 0.0061 0.0058
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0047 0.0087 0.0109
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Mycobacterium tuberculosis Possible alanine rich oxidoreductase 0.0028 0.004 0.0037
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Plasmodium falciparum lipid/sterol:H+ symporter 0.0018 0.0016 0.0014
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0028 0.0041 0.0034
Echinococcus multilocularis smad 0.0017 0.0013 0.0011
Chlamydia trachomatis aminopeptidase P 0.0023 0.0029 0.0057
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.016
Loa Loa (eye worm) G-protein coupled receptor 0.0219 0.0508 0.0508
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0167 0.1044
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0012 0.0003 0.0003
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0015 0.0013
Loa Loa (eye worm) MH2 domain-containing protein 0.0245 0.0571 0.0571
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0104 0.0228 0.0225
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0219 0.0508 0.0506
Echinococcus multilocularis transfer RNA-Lys 0.0021 0.0023 0.0021
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Echinococcus multilocularis tumor protein p63 0.0333 0.0788 0.0786
Echinococcus multilocularis Niemann Pick C1 protein 0.0297 0.0699 0.0697
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0036 0.0061 0.0075
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Loa Loa (eye worm) steroid hormone receptor 0.0063 0.0126 0.0126
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0054 0.0104 0.013
Echinococcus multilocularis fmrfamide receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.004 0.0038
Brugia malayi nuclear receptor NHR-88 0.0063 0.0126 0.0125
Loa Loa (eye worm) hypothetical protein 0.0053 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0156 0.0354 0.0354
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.006 0.0073
Onchocerca volvulus 0.0018 0.0016 0.0014
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0589 0.1413 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0127 0.0284 0.0284
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0025 0.0033 0.003
Trypanosoma cruzi AMP deaminase, putative 0.3172 0.7735 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.009 0.009
Brugia malayi MH2 domain containing protein 0.0017 0.0013 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0097 0.0121
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0076 0.0074
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0054 0.0104 0.013
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.006 0.0058
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0022 0.0024
Brugia malayi Tachykinin-like peptides receptor 99D 0.0219 0.0508 0.0506
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0014 0.0012
Onchocerca volvulus 0.0028 0.004 0.0037
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0012
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0039 0.0033
Loa Loa (eye worm) hypothetical protein 0.0124 0.0276 0.0276
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.006 0.0057
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0219 0.0508 0.0506
Brugia malayi Cathepsin L-like precursor 0.0028 0.004 0.0038
Echinococcus granulosus bloom syndrome protein 0.003 0.0045 0.0043
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0016 0.0016
Echinococcus multilocularis neuropeptide receptor A26 0.0768 0.1852 0.185
Leishmania major cathepsin L-like protease 0.0084 0.0178 0.0175
Brugia malayi orphan nuclear receptor NR2E1 0.003 0.0045 0.0043
Schistosoma mansoni hypothetical protein 0.0062 0.0125 0.0123
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0346 0.0819 0.0817
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0027
Echinococcus multilocularis methionyl aminopeptidase 2 0.0188 0.0432 0.043
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0219 0.0508 0.0506
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0038 0.0038
Mycobacterium ulcerans dipeptidase 0.0023 0.0029 0.0023
Brugia malayi topoisomerase 0.002 0.0022 0.002
Schistosoma mansoni aryl hydrocarbon receptor 0.0028 0.004 0.0038
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0048 0.0048
Echinococcus granulosus Protein patched homolog 1 0.0127 0.0284 0.0282
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.0331 0.0329
Echinococcus granulosus GPCR family 2 0.0062 0.0125 0.0123
Entamoeba histolytica adenosine deaminase, putative 0.4097 1 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1227 0.1227
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.003 0.0028
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Brugia malayi ImpB/MucB/SamB family protein 0.0076 0.0159 0.0157
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0016 0.0016
Brugia malayi Serotonin receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Trypanosoma cruzi DNA polymerase eta, putative 0.0076 0.0159 0.0203
Trichomonas vaginalis adenosine deaminase, putative 0.4097 1 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0219 0.0508 0.0506
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.006 0.0058
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0589 0.1413 0.1408
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Trypanosoma cruzi histone deacetylase, putative 0.0053 0.0102 0.0129
Schistosoma mansoni terminal deoxycytidyl transferase 0.0046 0.0085 0.0083
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Chlamydia trachomatis dehyroquinate synthase 0.0229 0.0533 0.3677
Brugia malayi Protein kinase domain containing protein 0.0038 0.0065 0.0063
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0051 0.0097 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1227 0.1227
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Echinococcus multilocularis lamin 0.009 0.0192 0.019
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0027
Trichomonas vaginalis helicase, putative 0.0021 0.0024 0.0024
Loa Loa (eye worm) metallopeptidase family M24 containing protein 0.0023 0.0029 0.0029
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.005 0.0061
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Entamoeba histolytica alcohol dehydrogenase, putative 0.0019 0.0019 0.0016
Trypanosoma brucei unspecified product 0.0032 0.005 0.0061
Brugia malayi hypothetical protein 0.0093 0.0201 0.0199
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Toxoplasma gondii histone deacetylase HDAC5 0.0053 0.0103 0.0103
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Giardia lamblia DINP protein human, muc B family 0.0046 0.0085 0.1245
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0121 0.0269 0.0263
Schistosoma mansoni aminopeptidase P1 (M24 family) 0.0023 0.0029 0.0027
Trypanosoma cruzi metallo-peptidase, Clan MG, Family M24, putative 0.0023 0.0029 0.0034
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0062 0.0123 0.1227
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0047 0.0088 0.0086
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.0012 0.001
Schistosoma mansoni inositol monophosphatase 0.0027 0.004 0.0038
Echinococcus multilocularis dnaJ subfamily B 0.0488 0.1167 0.1165
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0683 0.1644 0.1644
Echinococcus granulosus orexin receptor type 2 0.0219 0.0508 0.0506
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0028 0.0041 0.0038
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0097 0.021 0.021
Echinococcus granulosus aldo keto reductase 0.0066 0.0134 0.0132
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0219 0.0508 0.0506
Onchocerca volvulus 0.002 0.0022 0.0019
Plasmodium falciparum acyl-CoA synthetase 0.0091 0.0194 0.0191
Giardia lamblia DNA damage repair protein 0.0014 0.0007 0.0068
Mycobacterium ulcerans oxidoreductase 0.0066 0.0134 0.0128
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0098 0.0211 0.0211
Plasmodium falciparum flap endonuclease 1 0.0031 0.0048 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Echinococcus granulosus tyrosine protein kinase otk 0.0025 0.0034 0.0032
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0013 0.0005 0.0005
Plasmodium falciparum histone deacetylase 2 0.0053 0.0102 0.01
Trypanosoma brucei DNA damage repair protein, putative 0.0014 0.0007 0.0006
Loa Loa (eye worm) hypothetical protein 0.0135 0.0303 0.0303
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.0025 0.0034 0.0032
Echinococcus granulosus thyroid hormone receptor alpha 0.003 0.0045 0.0043
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0297 0.0699 0.0696
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0051 0.0097 0.0097
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0109 0.0137
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0219 0.0508 0.0506
Brugia malayi protein C24B5.3 0.0018 0.0016 0.0014
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0265 0.0621 0.0618
Brugia malayi latrophilin 2 splice variant baaae 0.0135 0.0303 0.0301
Brugia malayi Pax transcription activation domain interacting protein 0.002 0.0022 0.002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0043 0.0077 0.0074
Brugia malayi hypothetical protein 0.002 0.0022 0.002
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0028 0.004 0.004
Trypanosoma cruzi histone deacetylase, putative 0.0053 0.0102 0.0129
Echinococcus granulosus nephrin 0.0092 0.0197 0.0195
Onchocerca volvulus 0.0019 0.0019 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0075
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0051 0.0097 0.0095
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Plasmodium falciparum methionine aminopeptidase 1a, putative 0.0023 0.0029 0.0027
Brugia malayi Cathepsin L-like precursor 0.0028 0.004 0.0038
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.003 0.0045 0.0043
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0036 0.0061 0.0059
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0065 0.0062
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0048 0.0046
Loa Loa (eye worm) hypothetical protein 0.2263 0.5511 0.5511
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Brugia malayi hypothetical protein 0.0033 0.0054 0.0052
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0219 0.0508 0.0506
Trypanosoma brucei unspecified product 0.0032 0.005 0.0061
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0188 0.0432 0.0555
Brugia malayi AMP-binding enzyme family protein 0.0036 0.006 0.0058
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Schistosoma mansoni amine GPCR 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0013 0.0011
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0036 0.0061 0.0059
Trypanosoma cruzi trypanothione reductase, putative 0.0036 0.0061 0.0075
Schistosoma mansoni histone deacetylase 0.0098 0.0211 0.0209
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0047 0.0088 0.0086
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0028 0.0041 0.0034
Plasmodium vivax histone deacetylase 2, putative 0.0053 0.0102 0.01
Schistosoma mansoni survival motor neuron protein 0.0025 0.0034 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.0027 0.0027
Toxoplasma gondii methionine aminopeptidase 0.0023 0.0029 0.0029
Trypanosoma cruzi aminopeptidase P, putative 0.0023 0.0029 0.0034
Loa Loa (eye worm) hypothetical protein 0.0187 0.0429 0.0429
Echinococcus multilocularis expressed conserved protein 0.0279 0.0655 0.0653
Treponema pallidum exodeoxyribonuclease (exoA) 0.0062 0.0123 0.0121
Schistosoma mansoni flap endonuclease-1 0.0028 0.0041 0.0039
Leishmania major DNA polymerase kappa, putative 0.0046 0.0085 0.0082
Mycobacterium leprae Probable lipase LipE 0.0051 0.0097 0.009
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Schistosoma mansoni RAR-like nuclear receptor 0.0063 0.0126 0.0125
Brugia malayi Immunoglobulin I-set domain containing protein 0.0027 0.0038 0.0036
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Trypanosoma brucei 2,3-bisphosphoglycerate-independent phosphoglycerate mutase-like protein, putative 0.0019 0.002 0.0022
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0063 0.0126 0.0125
Trypanosoma cruzi histone deacetylase 1, putative 0.0098 0.0211 0.0269
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.01 0.0093
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0097 0.021 0.0268
Entamoeba histolytica hypothetical protein 0.0116 0.0256 0.0253
Brugia malayi Inositol-1 0.0027 0.004 0.0038
Echinococcus multilocularis g protein coupled receptor 0.0219 0.0508 0.0506
Mycobacterium ulcerans methionine aminopeptidase 0.0023 0.0029 0.0023
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0036 0.006 0.0057
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0026 0.0036 0.0034
Loa Loa (eye worm) hypothetical protein 0.0091 0.0196 0.0196
Loa Loa (eye worm) hypothetical protein 0.0093 0.0201 0.0201
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Schistosoma mansoni neuropeptide receptor 0.0219 0.0508 0.0506
Onchocerca volvulus 0.0219 0.0508 0.0505
Loa Loa (eye worm) hypothetical protein 0.0051 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0167 0.0165
Echinococcus granulosus biogenic amine 5HT receptor 0.0219 0.0508 0.0506
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.002 0.0022 0.0024
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0047 0.0087 0.0085
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.005 0.005
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0098 0.0211 0.0211
Echinococcus multilocularis cell adhesion molecule:down regulated by 0.0025 0.0034 0.0032
Schistosoma mansoni hypothetical protein 0.0123 0.0273 0.0271
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0065 0.0065
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0028 0.0041 0.0038
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Brugia malayi MH1 domain containing protein 0.0017 0.0013 0.0011
Brugia malayi Methionine aminopeptidase protein type I 0.0023 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Brugia malayi NADH-dependent xylose reductase 0.0019 0.0019 0.0017
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0033 0.0054 0.0052
Loa Loa (eye worm) patched family protein 0.0018 0.0016 0.0016
Trypanosoma brucei methionine aminopeptidase, putative 0.0023 0.0029 0.0034
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0028 0.0041 0.0034
Plasmodium falciparum glutathione reductase 0.0104 0.0228 0.0225
Echinococcus multilocularis neuropeptide receptor 0.0219 0.0508 0.0506
Schistosoma mansoni intermediate filament proteins 0.009 0.0192 0.019
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0014 0.0006 0.0004
Schistosoma mansoni 3-dehydroquinate synthase 0.0229 0.0533 0.0531
Schistosoma mansoni carbon catabolite repressor protein 0.0012 0.0003 0.0001
Echinococcus multilocularis histone deacetylase 6 0.0053 0.0102 0.01
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0121 0.0269 0.0263
Brugia malayi Fibroblast growth factor family protein 0.0048 0.009 0.0088
Trichomonas vaginalis inositol monophosphatase, putative 0.0027 0.004 0.004
Echinococcus granulosus cathepsin L 0.0014 0.0007 0.0005
Brugia malayi beta-lactamase 0.0051 0.0097 0.0095
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni basigin related 0.0025 0.0034 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.005 0.005
Brugia malayi MH2 domain containing protein 0.0245 0.0571 0.0569
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Brugia malayi hypothetical protein 0.002 0.0022 0.002
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0054 0.0104 0.0101
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0063 0.0126 0.0125
Toxoplasma gondii ABC1 family protein 0.0051 0.0097 0.0097
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0116 0.0256 0.0254
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0036 0.006 0.0053
Schistosoma mansoni tar DNA-binding protein 0.013 0.029 0.0288
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Schistosoma mansoni cathepsin F (C01 family) 0.0028 0.004 0.0038
Plasmodium vivax methionine aminopeptidase 2, putative 0.0188 0.0432 0.0429
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0054 0.0104 0.013
Loa Loa (eye worm) hypothetical protein 0.0036 0.006 0.006
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Treponema pallidum aminopeptidase P 0.0023 0.0029 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0513 0.1227 0.1227
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0063 0.0126 0.0126
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.007 0.007
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0063 0.0126 0.0125
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0003
Brugia malayi photoreceptor-specific nuclear receptor 0.0063 0.0126 0.0125
Echinococcus multilocularis histone deacetylase 6 0.0053 0.0102 0.01
Onchocerca volvulus Glucosylceramidase homolog 0.0336 0.0795 0.0793
Loa Loa (eye worm) hypothetical protein 0.0033 0.0054 0.0054
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0097 0.021 0.0268
Leishmania major histone deacetylase, putative 0.0098 0.0211 0.0208
Onchocerca volvulus 0.0051 0.0097 0.0094
Toxoplasma gondii methionine aminopeptidase 2, putative 0.0188 0.0432 0.0432
Trichomonas vaginalis D-aminoacylase, putative 0.0051 0.0097 0.0097
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Echinococcus multilocularis histone deacetylase 7 0.0053 0.0102 0.01
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0028 0.004 0.004
Onchocerca volvulus 0.0036 0.006 0.0057
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0036 0.0061 0.0058
Brugia malayi RNA recognition motif domain containing protein 0.013 0.029 0.0288
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0066 0.0134 0.0131
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.0098 0.0211 0.0211
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0027 0.004 0.0048
Onchocerca volvulus 0.0036 0.006 0.0057
Schistosoma mansoni single-minded 0.0028 0.004 0.0038
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0219 0.0508 0.0506
Trypanosoma cruzi FHA domain containing protein, putative 0.002 0.0022 0.0024
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0014 0.0007 0.0007
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0003 0.0001
Echinococcus multilocularis survival motor neuron protein 1 0.0124 0.0276 0.0274
Schistosoma mansoni amine GPCR 0.0219 0.0508 0.0506
Brugia malayi hypothetical protein 0.0219 0.0508 0.0506
Echinococcus granulosus microtubule associated protein 2 0.0202 0.0468 0.0466
Trypanosoma cruzi PAB1-binding protein , putative 0.0056 0.0109 0.0137
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0047 0.0087 0.0085
Schistosoma mansoni histone deacetylase 4 5 0.0053 0.0102 0.01
Toxoplasma gondii patched family protein 0.0018 0.0016 0.0016
Trypanosoma brucei aldo-keto reductase, putative 0.0066 0.0134 0.017
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0063 0.0126 0.0125
Schistosoma mansoni tar DNA-binding protein 0.013 0.029 0.0288
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0047 0.0087 0.0085
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0036 0.006 0.0057
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0109 0.0106
Brugia malayi nuclear hormone receptor 0.0063 0.0126 0.0125
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Schistosoma mansoni biogenic amine (5HT) receptor 0.0219 0.0508 0.0506
Echinococcus granulosus lachesin 0.0025 0.0034 0.0032
Brugia malayi nuclear receptor RXR 0.0033 0.0054 0.0052
Plasmodium vivax histone deacetylase 1, putative 0.0098 0.0211 0.0208
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0077 0.0077
Echinococcus granulosus tumor protein p63 0.0333 0.0788 0.0786
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0063 0.0126 0.0125
Echinococcus multilocularis neuropeptides capa receptor 0.0219 0.0508 0.0506
Schistosoma mansoni cell adhesion molecule 0.0025 0.0034 0.0032
Schistosoma mansoni aldo-keto reductase 0.0066 0.0134 0.0132
Plasmodium vivax histone deacetylase, putative 0.0053 0.0102 0.01
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0051 0.0097 0.0094
Entamoeba histolytica peptidase, putative 0.0023 0.0029 0.0027
Schistosoma mansoni hypothetical protein 0.0123 0.0273 0.0271
Brugia malayi hypothetical protein 0.0115 0.0254 0.0253
Echinococcus multilocularis nuclear receptor nhr 48 0.003 0.0045 0.0043
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.003 0.0028
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0017 0.0015 0.0016
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Mycobacterium tuberculosis Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) 0.0023 0.0029 0.0027
Schistosoma mansoni tar DNA-binding protein 0.013 0.029 0.0288
Brugia malayi Phospholipase A2 family protein 0.0073 0.015 0.0148
Schistosoma mansoni hypothetical protein 0.0219 0.0508 0.0506
Loa Loa (eye worm) hypothetical protein 0.0019 0.0018 0.0018
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Echinococcus granulosus xaa pro aminopeptidase 0.0023 0.0029 0.0027
Entamoeba histolytica aminopeptidase, putative 0.0023 0.0029 0.0027
Mycobacterium ulcerans beta-lactamase 0.0051 0.0097 0.009
Brugia malayi Patched protein homolog 1 0.0018 0.0016 0.0014
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.006 0.0058
Trypanosoma brucei histone deacetylase 4 0.0053 0.0102 0.0129
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0028 0.004 0.0038
Trypanosoma brucei DNA polymerase IV, putative 0.0046 0.0085 0.0106
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0058
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0147 0.0332 0.0426
Trichomonas vaginalis DNA helicase recq1, putative 0.003 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0042 0.0074 0.0074
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0028 0.0041 0.0034
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0014 0.0012
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0043 0.0041
Schistosoma mansoni histone deacetylase 4 5 0.0053 0.0102 0.01
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0027 0.0037 0.0035
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.005 0.005
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0025 0.0034 0.0032
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0036 0.006 0.0053
Echinococcus multilocularis histone deacetylase 0.0053 0.0102 0.01
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.01 0.0098
Brugia malayi AKH receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0014 0.0012
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0015 0.0013
Brugia malayi Cathepsin L-like cysteine proteinase 0.0019 0.0018 0.0016
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.003 0.0045 0.0043
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0025 0.0034 0.0031
Brugia malayi putative neuropeptide receptor NPR1 0.0219 0.0508 0.0506
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0026 0.0036 0.0034
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0014 0.0007 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0054 0.0104 0.0101
Brugia malayi Cytochrome P450 family protein 0.0038 0.0066 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Onchocerca volvulus Protein patched homolog 0.0018 0.0016 0.0014
Toxoplasma gondii hypothetical protein 0.005 0.0095 0.0095
Plasmodium vivax methionine aminopeptidase 1c, putative 0.0023 0.0029 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Trypanosoma cruzi AMP deaminase, putative 0.3172 0.7735 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0219 0.0508 0.0506
Trichomonas vaginalis esterase, putative 0.0051 0.0097 0.0097
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0025 0.0034 0.0032
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0028 0.0041 0.0038
Brugia malayi PAS domain containing protein 0.0028 0.004 0.0038
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0075
Echinococcus granulosus rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0058
Giardia lamblia Hypothetical protein 0.0048 0.009 0.1321
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0044 0.0079 0.0099
Leishmania major transcription factor-like protein 0.0023 0.0029 0.0027
Echinococcus granulosus beta LACTamase domain containing family member 0.0051 0.0097 0.0095
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Echinococcus granulosus replication factor c subunit 1 0.002 0.0022 0.002
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0012 0.0003 0.0001
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0028 0.0041 0.0049
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0043 0.0043
Schistosoma mansoni Smad4 0.0017 0.0013 0.0011
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.006 0.0057
Trypanosoma brucei DNA polymerase IV, putative 0.0046 0.0085 0.0106
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Loa Loa (eye worm) transcription factor SMAD2 0.0245 0.0571 0.0571
Brugia malayi Cathepsin L-like precursor 0.0019 0.0018 0.0016
Echinococcus multilocularis Down syndrome cell adhesion molecule 0.0027 0.0038 0.0036
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0238 0.0556 0.0553
Brugia malayi Peroxidasin 0.0025 0.0034 0.0032
Schistosoma mansoni AMP deaminase 0.3172 0.7735 0.7734
Echinococcus granulosus 7TM GPCR rhodopsin 0.0219 0.0508 0.0506
Echinococcus multilocularis irregular chiasm roughest protein immunoglobulin set domain containing protein 0.009 0.0193 0.0191
Trypanosoma cruzi DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Trypanosoma brucei Xaa-Pro aminopeptidase, putative 0.0023 0.0029 0.0034
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0012 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0066 0.0082
Brugia malayi neuropeptide F receptor 0.0219 0.0508 0.0506
Leishmania major 4-coumarate:coa ligase-like protein 0.0121 0.0269 0.0266
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0028 0.0041 0.0038
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Echinococcus multilocularis musashi 0.009 0.0192 0.019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.0331 0.0331
Echinococcus multilocularis bloom syndrome protein 0.003 0.0045 0.0043
Schistosoma mansoni zinc finger protein 0.003 0.0045 0.0043
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0027 0.0038 0.0045
Echinococcus granulosus chromobox protein 1 0.0067 0.0137 0.0135
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0039 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0051 0.0097 0.0121
Trypanosoma cruzi histone deacetylase, putative 0.0053 0.0102 0.0129
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Echinococcus multilocularis conserved hypothetical protein 0.009 0.0193 0.0191
Schistosoma mansoni hypothetical protein 0.0017 0.0014 0.0012
Loa Loa (eye worm) TK/ROR protein kinase 0.0038 0.0065 0.0065
Brugia malayi Histone deacetylase family protein 0.0053 0.0102 0.01
Mycobacterium leprae Conserved hypothetical protein 0.0047 0.0087 0.0081
Echinococcus multilocularis sex peptide receptor 0.0219 0.0508 0.0506
Trichomonas vaginalis 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0119 0.0264 0.0264
Trypanosoma cruzi cysteine peptidase, putative 0.0084 0.0178 0.0226
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0066 0.0066
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0036 0.0061 0.0055
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Schistosoma mansoni nuclear receptor 0.003 0.0045 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.0032 0.005 0.0061
Brugia malayi putative neuropeptide receptor 0.0219 0.0508 0.0506
Toxoplasma gondii patched family protein 0.0018 0.0016 0.0016
Schistosoma mansoni netrin receptor unc5 0.0025 0.0034 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.01 0.0098
Trichomonas vaginalis histone deacetylase, putative 0.0098 0.0211 0.0211
Trypanosoma brucei Metallopeptidase family M24, putative 0.0023 0.0029 0.0034
Schistosoma mansoni hypothetical protein 0.0028 0.0041 0.0039
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis g-protein coupled receptor 0.0219 0.0508 0.0506
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0028 0.0041 0.0034
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0063 0.0126 0.0125
Brugia malayi Dopamine receptor protein 1 0.0219 0.0508 0.0506
Leishmania major prostaglandin f synthase, putative 0.0066 0.0134 0.0131
Onchocerca volvulus 0.0219 0.0508 0.0505
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0062 0.0123 0.0117
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0014 0.0007 0.0006
Entamoeba histolytica hypothetical protein 0.0116 0.0256 0.0253
Entamoeba histolytica acyl-CoA synthetase, putative 0.0121 0.0269 0.0266
Plasmodium vivax glutathione reductase, putative 0.0104 0.0228 0.0225
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0033 0.0054 0.0052
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0167 0.0167
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0028 0.0041 0.0038
Trypanosoma cruzi DNA damage repair protein, putative 0.0014 0.0007 0.0006
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.006 0.0057
Brugia malayi adenosine monophosphate deaminase 0.3172 0.7735 0.7734
Echinococcus multilocularis rhodopsin orphan GPCR 0.0219 0.0508 0.0506
Echinococcus multilocularis cysteine protease 0.0028 0.004 0.0038
Brugia malayi GnHR receptor homolog 0.0219 0.0508 0.0506
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0063 0.0126 0.0126
Giardia lamblia Histone deacetylase 0.0098 0.0211 0.3154
Loa Loa (eye worm) hypothetical protein 0.0063 0.0126 0.0126
Trichomonas vaginalis Clan MG, familly M24, aminopeptidase P-like metallopeptidase 0.0023 0.0029 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0087 0.0087
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0097 0.021 0.0207
Echinococcus multilocularis xaa Pro dipeptidase 0.0023 0.0029 0.0027
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0036 0.0061 0.0058
Mycobacterium ulcerans acyl-CoA synthetase 0.0121 0.0269 0.0263
Leishmania major aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Brugia malayi Niemann-Pick C1 protein precursor 0.0297 0.0699 0.0697
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0138 0.031 0.0304
Loa Loa (eye worm) hypothetical protein 0.0012 0.0003 0.0003
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0219 0.0508 0.0506
Echinococcus granulosus netrin receptor unc 5 0.0042 0.0076 0.0074
Schistosoma mansoni nuclear receptor nhr-48 0.003 0.0045 0.0043
Echinococcus multilocularis neuropeptide s receptor 0.0768 0.1852 0.185
Plasmodium vivax patched family protein, putative 0.0018 0.0016 0.0014
Onchocerca volvulus Bile acid receptor homolog 0.0063 0.0126 0.0124
Brugia malayi Immunoglobulin I-set domain containing protein 0.0025 0.0034 0.0032
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0032 0.005 0.005
Echinococcus multilocularis lachesin 0.0025 0.0034 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.0084 0.0178 0.0226
Plasmodium vivax histone deacetylase, putative 0.0053 0.0102 0.01
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0028 0.0041 0.0038
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.01 0.0097
Echinococcus multilocularis pro neuregulin 2, membrane bound 0.0025 0.0034 0.0032
Plasmodium falciparum replication factor C subunit 1, putative 0.002 0.0022 0.0019
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0036 0.0061 0.0055
Plasmodium falciparum ataxin-2 like protein, putative 0.0056 0.0109 0.0106
Echinococcus multilocularis cpg binding protein 0.0098 0.0211 0.0209
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0018 0.0015
Echinococcus multilocularis histone deacetylase 8 0.0616 0.1481 0.1479
Schistosoma mansoni ap endonuclease 0.0062 0.0123 0.0121
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0062 0.0123 0.0156
Entamoeba histolytica adenosine deaminase, putative 0.4097 1 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0116 0.0256 0.0254
Brugia malayi DKFZp564C0469 protein 0.002 0.0022 0.002
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0025 0.0034 0.0034
Echinococcus granulosus histone deacetylase 7 0.0053 0.0102 0.01
Onchocerca volvulus 0.0028 0.004 0.0037
Schistosoma mansoni blooms syndrome DNA helicase 0.0016 0.0012 0.001
Echinococcus multilocularis g protein coupled receptor 0.0219 0.0508 0.0506
Echinococcus multilocularis thioredoxin glutathione reductase 0.0104 0.0228 0.0226
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0019 0.0019 0.0019
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0012 0.0003 0.0001
Loa Loa (eye worm) TYRA-2 protein 0.0219 0.0508 0.0508
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Onchocerca volvulus Phospholipase A2 homolog 0.0073 0.015 0.0147
Leishmania major cathepsin L-like protease 0.0028 0.004 0.0037
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.006 0.0058
Mycobacterium ulcerans hypothetical protein 0.0121 0.0269 0.0263
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Mycobacterium tuberculosis Probable lipase LipD 0.0051 0.0097 0.0094
Schistosoma mansoni voltage-gated potassium channel 0.0051 0.0098 0.0096
Brugia malayi Histone deacetylase family protein 0.0053 0.0102 0.01
Trypanosoma cruzi metallo- peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Brugia malayi Intermediate filament tail domain containing protein 0.009 0.0192 0.019
Schistosoma mansoni smad1 5 8 and 0.0017 0.0013 0.0011
Brugia malayi Kringle domain containing protein 0.0038 0.0065 0.0063
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0311 0.0733 0.0945
Loa Loa (eye worm) hypothetical protein 0.0088 0.0188 0.0188
Entamoeba histolytica hypothetical protein 0.002 0.0022 0.0019
Loa Loa (eye worm) hypothetical protein 0.0079 0.0167 0.0167
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0046 0.0085 0.0083
Echinococcus granulosus dna polymerase eta 0.0076 0.0159 0.0157
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0036 0.0061 0.0075
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0219 0.0508 0.0506
Echinococcus granulosus inositol monophosphatase 1 0.0027 0.004 0.0038
Onchocerca volvulus 0.0028 0.004 0.0037
Schistosoma mansoni histone deacetylase 1 2 3 0.0616 0.1481 0.1479
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0012 0.0002 0.0002
Leishmania major DNA polymerase eta, putative 0.0045 0.0082 0.0079
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0013 0.0004 0.0001
Echinococcus multilocularis neuropeptide receptor 0.0219 0.0508 0.0506
Mycobacterium ulcerans DNA polymerase IV 0.0046 0.0085 0.0079
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0036 0.006 0.0073
Trypanosoma brucei metallo-peptidase, Clan MG, Family M24 0.0023 0.0029 0.0034
Trypanosoma brucei histone deacetylase 3 0.0053 0.0102 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Onchocerca volvulus Cathepsin L homolog 0.0028 0.004 0.0037
Mycobacterium tuberculosis Probable cytoplasmic peptidase PepQ 0.0023 0.0029 0.0027
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0036 0.006 0.0053
Trypanosoma brucei AMP deaminase, putative 0.3172 0.7735 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0065 0.0065
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0047 0.0087 0.0085
Toxoplasma gondii hypothetical protein 0.0018 0.0016 0.0016
Trichomonas vaginalis aldo-keto reductase, putative 0.0019 0.0019 0.0019
Mycobacterium tuberculosis Possible oxidoreductase 0.0028 0.004 0.0037
Trypanosoma cruzi cysteine peptidase, putative 0.0028 0.004 0.0048
Loa Loa (eye worm) patched family protein 0.0018 0.0016 0.0016
Onchocerca volvulus 0.0219 0.0508 0.0505
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0063 0.0126 0.0125
Echinococcus granulosus chromobox protein 1 0.0067 0.0137 0.0135
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0063 0.0126 0.0125
Onchocerca volvulus 0.009 0.0192 0.0189
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0043 0.0078 0.0076
Trichomonas vaginalis histone deacetylase, putative 0.0098 0.0211 0.0211
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Schistosoma mansoni nephrin related 0.0025 0.0034 0.0032
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0044 0.0079 0.0099
Loa Loa (eye worm) hypothetical protein 0.0683 0.1644 0.1644
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.2263 0.5511 0.5511
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0013 0.0005 0.0003
Echinococcus multilocularis adenosine deaminase 0.4097 1 1
Onchocerca volvulus 0.0066 0.0134 0.0131
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.0012 0.0012
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.006 0.0057
Brugia malayi Smad1 0.0017 0.0013 0.0011
Onchocerca volvulus 0.0219 0.0508 0.0505
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0117 0.0258 0.0258
Plasmodium vivax methionine aminopeptidase 1b, putative 0.0023 0.0029 0.0027
Mycobacterium tuberculosis Probable hydrolase 0.0051 0.0097 0.0094
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0028 0.0041 0.0038
Trichomonas vaginalis penicillin-binding protein, putative 0.0051 0.0097 0.0097
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.003 0.0045 0.0043
Schistosoma mansoni cell adhesion molecule 0.0025 0.0034 0.0032
Wolbachia endosymbiont of Brugia malayi methionine aminopeptidase 0.0023 0.0029 0.0095
Echinococcus multilocularis geminin 0.0373 0.0885 0.0883
Schistosoma mansoni alpha-1 adrenergic receptor 0.0219 0.0508 0.0506
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0066 0.006
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Leishmania major cathepsin L-like protease 0.0028 0.004 0.0037
Echinococcus granulosus Niemann Pick C1 protein 0.0297 0.0699 0.0697
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Wolbachia endosymbiont of Brugia malayi Xaa-Pro aminopeptidase 0.0023 0.0029 0.0095
Echinococcus granulosus tar DNA binding protein 0.013 0.029 0.0288
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.006 0.0057
Loa Loa (eye worm) hypothetical protein 0.0024 0.0031 0.0031
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0091 0.0196 0.019
Loa Loa (eye worm) oxidoreductase 0.0066 0.0134 0.0134
Brugia malayi Cathepsin L-like precursor 0.0028 0.004 0.0038
Echinococcus granulosus methionyl aminopeptidase 1 M24 family 0.0023 0.0029 0.0027
Onchocerca volvulus 0.003 0.0045 0.0042
Brugia malayi nuclear hormone receptor 0.003 0.0045 0.0043
Brugia malayi Patched related family protein 4 0.0018 0.0016 0.0014
Schistosoma mansoni cytochrome P450 0.0028 0.0041 0.0039
Trypanosoma cruzi DNA polymerase eta, putative 0.0045 0.0082 0.0102
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.006 0.0073
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0063 0.0126 0.0125
Echinococcus granulosus tm gpcr rhodopsin 0.0219 0.0508 0.0506
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0007 0.0005
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0016
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0301 0.071 0.0708
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0019 0.0019 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0046 0.0085 0.0106
Schistosoma mansoni methionyl aminopeptidase 1 (M24 family) 0.0023 0.0029 0.0027
Onchocerca volvulus 0.0219 0.0508 0.0505
Toxoplasma gondii histone deacetylase HDAC1 0.0053 0.0102 0.0102
Brugia malayi Immunoglobulin I-set domain containing protein 0.0117 0.0258 0.0256
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.036 0.0852 0.0847
Onchocerca volvulus 0.0219 0.0508 0.0505
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0097 0.021 0.021
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Mycobacterium leprae PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) 0.0023 0.0029 0.0023
Echinococcus granulosus aldo keto reductase 0.0066 0.0134 0.0132
Echinococcus multilocularis sterol regulatory element binding protein 0.0127 0.0284 0.0282
Mycobacterium ulcerans acyl-CoA synthetase 0.0036 0.006 0.0053
Schistosoma mansoni cell adhesion molecule 0.0027 0.0038 0.0036
Loa Loa (eye worm) fibroinase 0.0028 0.004 0.004
Schistosoma mansoni hypothetical protein 0.0488 0.1167 0.1165
Echinococcus multilocularis GPCR, family 2 0.0062 0.0125 0.0123
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0066 0.0134 0.0132
Echinococcus granulosus methionine aminopeptidase type I 0.0023 0.0029 0.0027
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0051 0.0097 0.0094
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0091 0.0194 0.1241
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0167 0.0164
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0003 0.0001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.0331 0.0329
Loa Loa (eye worm) hypothetical protein 0.0073 0.015 0.015
Trypanosoma brucei AMP deaminase, putative 0.3172 0.7735 1
Echinococcus granulosus Ankyrin 0.0017 0.0015 0.0013
Trichomonas vaginalis set domain proteins, putative 0.0123 0.0273 0.0273
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0086 0.0182 0.0179
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0024 0.0024
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0043 0.0078 0.0076
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0036 0.0061 0.0058
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0066 0.0134 0.0132
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0219 0.0508 0.0506
Trypanosoma brucei prostaglandin f synthase 0.0066 0.0134 0.017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0196 0.0453 0.0451
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0121 0.0269 0.0263
Loa Loa (eye worm) melatonin receptor type 1A 0.0219 0.0508 0.0508
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0028 0.0041 0.0034
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0047 0.0087 0.0085
Trypanosoma brucei beta lactamase 0.0014 0.0006 0.0005
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0025 0.0033 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0063 0.0126 0.0126
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0063 0.0126 0.0126
Brugia malayi follicle stimulating hormone receptor 0.072 0.1735 0.1734
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0097 0.021 0.0208
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0036 0.0061 0.0058
Brugia malayi Protein kinase domain containing protein 0.0017 0.0014 0.0012
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0211 0.0489 0.0487
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Trichomonas vaginalis aldo-keto reductase, putative 0.0066 0.0134 0.0134
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0084 0.0178 0.0226
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0044 0.0042
Loa Loa (eye worm) hypothetical protein 0.0028 0.004 0.004
Schistosoma mansoni nocturnin 0.0012 0.0003 0.0001
Trichomonas vaginalis glucosylceramidase, putative 0.0354 0.084 0.084
Schistosoma mansoni hypothetical protein 0.0025 0.0034 0.0032
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0036 0.0036
Entamoeba histolytica cysteine protease, putative 0.0014 0.0007 0.0004
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0062 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0219 0.0508 0.0508
Plasmodium vivax replication factor C subunit 1, putative 0.002 0.0022 0.0019
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0043 0.0077 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0028 0.004 0.004
Brugia malayi MH2 domain containing protein 0.0017 0.0013 0.0011
Brugia malayi G-protein coupled receptor 0.0219 0.0508 0.0506
Loa Loa (eye worm) nuclear hormone receptor 0.003 0.0045 0.0045
Brugia malayi nuclear hormone receptor family member odr-7 0.003 0.0045 0.0043
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0513 0.1227 0.1225
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0034 0.0034
Plasmodium falciparum aldehyde reductase, putative 0.0019 0.0019 0.0016
Onchocerca volvulus 0.0028 0.004 0.0037
Onchocerca volvulus 0.0063 0.0126 0.0124
Echinococcus granulosus intermediate filament protein 0.009 0.0192 0.019
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0017 0.0014 0.0014
Onchocerca volvulus 0.0051 0.0097 0.0094
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.3172 0.7735 0.7734
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.0027 0.0038 0.0045
Giardia lamblia Xaa-Pro dipeptidase 0.0023 0.0029 0.0402
Echinococcus multilocularis hemicentin 1 0.0025 0.0034 0.0032
Onchocerca volvulus AMP deaminase 2 homolog 0.3172 0.7735 0.7734
Echinococcus granulosus Nuclear hormone receptor HR96 0.003 0.0045 0.0043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0127 0.0284 0.0284
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0027 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0078 0.0078
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0028 0.004 0.0037
Schistosoma mansoni biogenic amine receptor 0.0219 0.0508 0.0506
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0063 0.0126 0.0125
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0054 0.0104 0.0102
Brugia malayi Patched family protein 0.0018 0.0016 0.0014
Trypanosoma cruzi 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, putative 0.0019 0.002 0.0022
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0028 0.004 0.0037
Echinococcus multilocularis Proliferation associated protein 2G4 0.0023 0.0029 0.0027
Echinococcus multilocularis voltage gated potassium channel 0.0016 0.0012 0.001
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Entamoeba histolytica recQ family helicase, putative 0.0027 0.0038 0.0035
Loa Loa (eye worm) hypothetical protein 0.003 0.0045 0.0045
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0091 0.0194 0.0188

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 3 % Compound was tested for its antagonistic activity at 100 microM concentration against SH2 domain of LCK protein. ChEMBL. 9871587
Inhibition (functional) = 3 % Compound was tested for its antagonistic activity at 100 microM concentration against SH2 domain of LCK protein. ChEMBL. 9871587
Inhibition (binding) = 6 % Antagonistic activity at 100 microM concentration against SH-2 domain of growth factor receptor binding protein (Grb2). ChEMBL. 9871587
Inhibition (binding) = 6 % Antagonistic activity at 100 microM concentration against SH-2 domain of growth factor receptor binding protein (Grb2). ChEMBL. 9871587
Inhibition (functional) = 16 % Antagonistic activity at 100 microMolar concentration to the SH2 domain of ZAP-70 protein. ChEMBL. 9871587
Inhibition (functional) = 16 % Antagonistic activity at 100 microMolar concentration to the SH2 domain of ZAP-70 protein. ChEMBL. 9871587

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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