Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 50 ug ml-1 | In vitro antibacterial activity against erythromycin-susceptible Staphylococcus aureus 209P-JC strain | ChEMBL. | 11708904 |
MIC (functional) | > 100 ug ml-1 | In vitro antibacterial activity against an inducibly MLS B resistant Staphylococcus aureus B1 strain | ChEMBL. | 11708904 |
MIC (functional) | > 100 ug ml-1 | In vitro antibacterial activity against constitutively MLS B resistant Staphylococcus aureus SR138 strain encoded by an ermA gene | ChEMBL. | 11708904 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.