Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | dihydrofolate reductase-thymidylate synthase | 0.0122 | 0.1893 | 1 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0015 | 0.012 | 0.0635 |
Echinococcus granulosus | lamin dm0 | 0.0012 | 0.0054 | 0.0379 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0367 | 0.0367 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0367 | 0.0792 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0013 | 0.0086 | 0.037 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0367 | 0.2551 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.002 | 0.0188 | 0.1306 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0022 | 0.0234 | 0.0234 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0234 | 0.0506 |
Echinococcus granulosus | dihydrofolate reductase | 0.0035 | 0.0451 | 0.3133 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.0035 | 0.0451 | 0.3455 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0041 | 0.0538 | 0.2844 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Brugia malayi | thymidylate synthase | 0.0087 | 0.1305 | 0.2815 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0367 | 0.2551 |
Echinococcus granulosus | lamin | 0.0012 | 0.0054 | 0.0379 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | ap endonuclease | 0.0009 | 0.0017 | 0.0118 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0019 | 0.0184 | 0.0184 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0234 | 0.0506 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0088 | 0.1326 | 0.6701 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.0181 | 0.0956 |
Brugia malayi | hypothetical protein | 0.0041 | 0.0549 | 0.1184 |
Echinococcus multilocularis | thymidylate synthase | 0.0087 | 0.1305 | 0.1305 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0009 | 0.0017 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0022 | 0.0234 | 0.0506 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0015 | 0.012 | 0.0635 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.0181 | 0.0956 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0015 | 0.012 | 0.0921 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0015 | 0.012 | 0.0921 |
Brugia malayi | ecdysteroid receptor | 0.0287 | 0.4635 | 1 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0015 | 0.012 | 0.0921 |
Onchocerca volvulus | 0.003 | 0.0367 | 0.0682 | |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0367 | 0.2551 |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0367 | 0.0792 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.0035 | 0.0451 | 0.0973 |
Trypanosoma brucei | unspecified product | 0.001 | 0.0032 | 0.0169 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.0041 | 0.0549 | 0.29 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0015 | 0.012 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.003 | 0.0367 | 0.0682 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0367 | 0.2551 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0012 | 0.0054 | 0.0118 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0367 | 0.0367 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0041 | 0.0538 | 0.3742 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0041 | 0.0538 | 0.278 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0367 | 0.2551 |
Loa Loa (eye worm) | lipocalin/cytosolic fatty-acid binding protein family protein | 0.0019 | 0.0184 | 0.0397 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0009 | 0.0017 | 0.0086 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0367 | 0.2551 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0025 | 0.0281 | 0.1485 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0367 | 0.2551 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0087 | 0.1305 | 0.9068 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0367 | 0.2551 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0015 | 0.012 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0287 | 0.4635 | 1 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0041 | 0.0538 | 0.2844 |
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0029 | 0.0352 | 0.1785 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0083 | 0.1251 | 0.2612 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | neuropeptide receptor | 0.0095 | 0.1439 | 1 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.0181 | 0.0956 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0367 | 0.2551 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.0122 | 0.1893 | 1 |
Schistosoma mansoni | pyruvate carboxylase | 0.0015 | 0.012 | 0.0835 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0367 | 0.0792 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0015 | 0.012 | 0.012 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0367 | 0.2551 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0367 | 0.0792 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0367 | 0.0792 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0009 | 0.0017 | 0.0118 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | ap endonuclease | 0.0009 | 0.0017 | 0.0118 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.002 | 0.0188 | 0.1306 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0367 | 0.2551 |
Brugia malayi | Lipocalin / cytosolic fatty-acid binding protein family protein | 0.0019 | 0.0184 | 0.0397 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0127 | 0.1978 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0367 | 0.0792 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0009 | 0.0017 | 0.0037 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.0181 | 0.1258 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.0035 | 0.0451 | 0.2791 |
Loa Loa (eye worm) | intermediate filament protein | 0.0012 | 0.0054 | 0.0118 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0015 | 0.012 | 0.0635 |
Echinococcus granulosus | intermediate filament protein | 0.0012 | 0.0054 | 0.0379 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Toxoplasma gondii | pyruvate carboxylase | 0.0015 | 0.012 | 0.055 |
Schistosoma mansoni | fatty acid binding protein | 0.0019 | 0.0184 | 0.1278 |
Leishmania major | DNA polymerase eta, putative | 0.0013 | 0.0086 | 0.0457 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.002 | 0.0188 | 0.1306 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0012 | 0.0054 | 0.0118 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0367 | 0.0792 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0367 | 0.0792 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0009 | 0.0017 | 0.0037 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0041 | 0.0538 | 0.278 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0022 | 0.0234 | 0.0506 |
Schistosoma mansoni | dihydrofolate reductase | 0.0035 | 0.0451 | 0.3133 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0367 | 0.0792 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0019 | 0.0184 | 0.0184 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0.0367 | 0.0367 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0367 | 0.0792 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.0087 | 0.1305 | 1 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0009 | 0.0017 | 0.009 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.002 | 0.0188 | 0.1306 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0367 | 0.0792 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0013 | 0.0086 | 0.0457 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.0181 | 0.039 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Onchocerca volvulus | 0.0087 | 0.1305 | 0.2729 | |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.0087 | 0.1305 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0367 | 0.0792 |
Chlamydia trachomatis | dihydrofolate reductase | 0.0035 | 0.0451 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0095 | 0.1439 | 0.1439 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0015 | 0.012 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0367 | 0.2551 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0041 | 0.0549 | 0.4206 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0367 | 0.2551 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0367 | 0.2551 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0015 | 0.012 | 0.0835 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0009 | 0.0017 | 0.009 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0051 | 0.011 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0019 | 0.0184 | 0.1278 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0015 | 0.012 | 0.0921 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0549 | 0.2774 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0367 | 0.2551 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0367 | 0.0367 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.0181 | 0.0181 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.002 | 0.0188 | 0.0188 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0022 | 0.0234 | 0.1629 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0041 | 0.0538 | 0.0538 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.002 | 0.0188 | 0.0405 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0009 | 0.0017 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0054 | 0.0118 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.0122 | 0.1893 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0009 | 0.0017 | 0.009 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0009 | 0.0017 | 0.0017 |
Brugia malayi | Dihydrofolate reductase | 0.0035 | 0.0451 | 0.0973 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0039 | 0.0515 | 0.111 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0181 | 0.039 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0127 | 0.1978 | 1 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0039 | 0.0515 | 0.111 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0367 | 0.2551 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0041 | 0.0538 | 0.3742 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0127 | 0.1978 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.0087 | 0.1305 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.002 | 0.0188 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.4635 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0367 | 0.0792 |
Brugia malayi | dihydrofolate reductase family protein | 0.0035 | 0.0451 | 0.0973 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0367 | 0.0367 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0367 | 0.2551 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0009 | 0.0017 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0122 | 0.1893 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0022 | 0.0234 | 0.1629 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.0122 | 0.1893 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0367 | 0.2551 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0367 | 0.0792 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.0122 | 0.1893 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0367 | 0.0792 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0095 | 0.1439 | 0.1439 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0083 | 0.1251 | 0.6323 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | intermediate filament proteins | 0.0012 | 0.0054 | 0.0379 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0088 | 0.1326 | 0.6701 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.002 | 0.0188 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0367 | 0.0792 |
Echinococcus multilocularis | dihydrofolate reductase | 0.0035 | 0.0451 | 0.0451 |
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.0015 | 0.012 | 0.0635 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0367 | 0.2551 |
Brugia malayi | intermediate filament protein | 0.0012 | 0.0054 | 0.0118 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0367 | 0.0792 |
Schistosoma mansoni | lamin | 0.0012 | 0.0054 | 0.0379 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.002 | 0.0188 | 0.1306 |
Schistosoma mansoni | fatty acid binding protein | 0.0019 | 0.0184 | 0.1278 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0009 | 0.0017 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0012 | 0.0054 | 0.0054 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0367 | 0.2551 |
Loa Loa (eye worm) | thymidylate synthase | 0.0087 | 0.1305 | 0.2815 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0009 | 0.0017 | 0.013 |
Schistosoma mansoni | lamin | 0.0012 | 0.0054 | 0.0379 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0234 | 0.0506 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.0181 | 0.1258 |
Echinococcus granulosus | thymidylate synthase | 0.0087 | 0.1305 | 0.9068 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0127 | 0.1978 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0127 | 0.1978 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0127 | 0.1978 | 0.4268 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0127 | 0.1978 | 0.4268 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0009 | 0.0017 | 0.009 |
Leishmania major | carboxylase, putative | 0.0015 | 0.012 | 0.0635 |
Echinococcus multilocularis | musashi | 0.0012 | 0.0054 | 0.0054 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0367 | 0.0367 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0367 | 0.0792 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0367 | 0.0792 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0367 | 0.0792 |
Echinococcus granulosus | neuropeptide receptor | 0.0095 | 0.1439 | 1 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0015 | 0.012 | 0.0921 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0029 | 0.0352 | 0.1785 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0367 | 0.2551 |
Echinococcus multilocularis | lamin | 0.0012 | 0.0054 | 0.0054 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0367 | 0.0367 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0367 | 0.0367 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0367 | 0.2551 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0127 | 0.1978 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0009 | 0.0017 | 0.013 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0022 | 0.0234 | 0.1629 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0015 | 0.012 | 0.0921 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.0035 | 0.0451 | 0.3455 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0367 | 0.0792 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.003 | 0.0367 | 0.0682 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0015 | 0.012 | 0.0835 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0019 | 0.0184 | 0.1278 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 5.1 uM | In vitro antiviral activity against human cytomegalovirus by plaque method. | ChEMBL. | 7562947 |
IC50 (functional) | = 41 uM | Antiviral activity against herpes simplex virus type 1(HSV-1) ELISA method | ChEMBL. | 7562947 |
IC50 (functional) | > 100 uM | Visual cytotoxicity scored on HFF cells at the time of HCMV plaque enumeration. | ChEMBL. | 7562947 |
IC50 (functional) | > 100 uM | Visual cytotoxicity scored on HFF cells at the time of HCMV plaque enumeration. | ChEMBL. | 7562947 |
IC50 (functional) | = 176 uM | In vitro inhibition of KB cell proliferation. | ChEMBL. | 7562947 |
IC50 (functional) | = 176 uM | In vitro inhibition of KB cell proliferation. | ChEMBL. | 7562947 |
IC90 (functional) | > 100 uM | In vitro antiviral activity against human cytomegalovirus by yield reduction assay. | ChEMBL. | 7562947 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.