Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0031 | 0.01 | 0.01 |
Toxoplasma gondii | selenide, water dikinase | 0.0062 | 0.0576 | 0.0576 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0062 | 0.0576 | 0.5138 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0234 | 0.3218 | 0.3218 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0172 | 0.2263 | 0.2263 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0062 | 0.0576 | 0.0016 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0234 | 0.3218 | 0.3218 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0062 | 0.0576 | 0.0576 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.01 | 0.01 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0234 | 0.3218 | 0.3218 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0677 | 1 | 1 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0031 | 0.01 | 0.01 |
Brugia malayi | Muscleblind-like protein | 0.0145 | 0.184 | 0.184 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.014 | 0.1764 | 0.1764 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.103 | 0.103 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0031 | 0.01 | 0.01 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Mycobacterium ulcerans | dehydrogenase | 0.0062 | 0.0576 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.2139 | 0.2139 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0062 | 0.0576 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.01 | 0.01 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0031 | 0.01 | 0.01 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0062 | 0.0576 | 0.0576 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0062 | 0.0576 | 0.1789 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0062 | 0.0576 | 0.0005 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.014 | 0.014 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0062 | 0.0576 | 0.0576 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0241 | 0.0241 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0072 | 0.0724 | 0.0724 |
Echinococcus granulosus | geminin | 0.0164 | 0.2139 | 0.2139 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0301 | 0.0301 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0234 | 0.3218 | 0.3218 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0062 | 0.0576 | 0.0005 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.01 | 0.01 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0062 | 0.0576 | 0.0576 |
Plasmodium falciparum | glutathione reductase | 0.0677 | 1 | 1 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0062 | 0.0576 | 0.0576 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0062 | 0.0576 | 0.5138 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.1121 | 1 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0062 | 0.0576 | 0.0016 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0677 | 1 | 1 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0234 | 0.3218 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0145 | 0.184 | 0.184 |
Leishmania major | hypothetical protein, conserved | 0.0062 | 0.0576 | 0.0576 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0062 | 0.0572 | 0.0572 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0062 | 0.0576 | 0.0005 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0234 | 0.3218 | 0.3218 |
Giardia lamblia | Glutamate synthase | 0.0062 | 0.0576 | 0.1789 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0062 | 0.0576 | 0.0576 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0031 | 0.01 | 0.01 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0062 | 0.0576 | 0.0576 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0062 | 0.0576 | 0.0005 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0062 | 0.0576 | 0.0005 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | jmjC domain containing protein | 0.0117 | 0.1415 | 0.1415 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0031 | 0.01 | 0.01 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0072 | 0.0724 | 0.0724 |
Echinococcus multilocularis | geminin | 0.0164 | 0.2139 | 0.2139 |
Schistosoma mansoni | hypothetical protein | 0.0164 | 0.2139 | 0.2139 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0062 | 0.0576 | 0.0576 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0062 | 0.0576 | 0.5138 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0572 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.01 | 0.01 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | protein phosphatase 2C | 0.0031 | 0.01 | 0.01 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0031 | 0.01 | 0.01 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0062 | 0.0576 | 0.0576 |
Brugia malayi | Fli-1 protein | 0.0218 | 0.2969 | 0.2969 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0031 | 0.01 | 0.01 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0062 | 0.0576 | 0.0005 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0062 | 0.0576 | 0.1789 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0234 | 0.3218 | 0.2807 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.014 | 0.014 |
Trypanosoma brucei | NADH dehydrogenase | 0.0062 | 0.0576 | 0.0576 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.01 | 0.01 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0072 | 0.0724 | 0.0724 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0234 | 0.3218 | 0.2807 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.103 | 0.103 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0062 | 0.0576 | 0.0576 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0234 | 0.3218 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0062 | 0.0576 | 0.1789 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0062 | 0.0576 | 0.1789 |
Plasmodium falciparum | thioredoxin reductase | 0.0234 | 0.3218 | 0.3218 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0062 | 0.0576 | 0.1789 |
Loa Loa (eye worm) | fli-1 protein | 0.0218 | 0.2969 | 0.2969 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0062 | 0.0576 | 0.0576 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0117 | 0.1415 | 0.1415 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0234 | 0.3218 | 0.3218 |
Mycobacterium tuberculosis | Probable reductase | 0.0062 | 0.0576 | 0.0005 |
Loa Loa (eye worm) | glutathione reductase | 0.0677 | 1 | 1 |
Schistosoma mansoni | jumonji domain containing protein | 0.0117 | 0.1415 | 0.1415 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0117 | 0.1415 | 0.1415 |
Mycobacterium ulcerans | hypothetical protein | 0.0062 | 0.0576 | 0.0016 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0062 | 0.0576 | 0.0576 |
Leishmania major | hypothetical protein, conserved | 0.0031 | 0.01 | 0.01 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.0265 | 0.0265 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0062 | 0.0576 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.0576 | 0.0576 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | phd:f box containing protein | 0.0031 | 0.01 | 0.01 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0062 | 0.0576 | 0.1789 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0234 | 0.3218 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.038 | 0.038 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0234 | 0.3218 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.014 | 0.1764 | 0.1764 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0677 | 1 | 1 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0062 | 0.0576 | 0.5138 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.01 | 0.01 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0031 | 0.01 | 0.01 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0062 | 0.0576 | 0.0016 |
Treponema pallidum | NADH oxidase | 0.0234 | 0.3218 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0099 | 0.1144 | 0.1144 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0301 | 0.0301 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0301 | 0.0301 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0062 | 0.0576 | 0.0576 |
Echinococcus granulosus | phd:f box containing protein | 0.0031 | 0.01 | 0.01 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0301 | 0.0301 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0062 | 0.0576 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0241 | 0.0241 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0241 | 0.0241 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0355 | 0.0355 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.1121 | 0.1121 |
Toxoplasma gondii | thioredoxin reductase | 0.0677 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0234 | 0.3218 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0062 | 0.0576 | 0.0576 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0062 | 0.0576 | 0.1789 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0062 | 0.0576 | 0.1789 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.1121 | 0.1121 |
Plasmodium vivax | JmjC domain containing protein | 0.0031 | 0.01 | 0.01 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0062 | 0.0576 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0265 | 0.0265 |
Brugia malayi | Thioredoxin reductase | 0.0677 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | glutamate synthase | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0576 | 0.0576 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0677 | 1 | 1 |
Schistosoma mansoni | glutamate synthase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.0265 | 0.0265 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Leishmania major | hypothetical protein, conserved | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0301 | 0.0301 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | muscleblind protein | 0.0145 | 0.184 | 0.184 |
Mycobacterium ulcerans | monoxygenase | 0.0062 | 0.0576 | 0.0016 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0117 | 0.1415 | 0.1415 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0117 | 0.1415 | 0.1415 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0117 | 0.1415 | 0.1415 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0062 | 0.0576 | 0.0576 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0234 | 0.3218 | 0.3218 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0062 | 0.0576 | 0.0016 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0062 | 0.0576 | 0.1789 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0234 | 0.3218 | 0.3218 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0677 | 1 | 1 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0062 | 0.0576 | 0.0576 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0062 | 0.0576 | 0.0016 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0062 | 0.0576 | 0.1789 |
Brugia malayi | Ets-domain containing protein | 0.0072 | 0.0724 | 0.0724 |
Leishmania major | trypanothione reductase | 0.0677 | 1 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0234 | 0.3218 | 0.3218 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | jmjC domain containing protein | 0.0031 | 0.01 | 0.01 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0062 | 0.0576 | 0.0576 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.0265 | 0.0265 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0031 | 0.01 | 0.01 |
Schistosoma mansoni | phd/f-box containing protein | 0.0031 | 0.01 | 0.01 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0031 | 0.01 | 0.01 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0031 | 0.01 | 0.01 |
Leishmania major | hypothetical protein, conserved | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0062 | 0.0572 | 0.0572 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0062 | 0.0576 | 0.0016 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0234 | 0.3218 | 0.3218 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0062 | 0.0576 | 0.0576 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0062 | 0.0576 | 0.5138 |
Schistosoma mansoni | ets-related | 0.0218 | 0.2969 | 0.2969 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0031 | 0.01 | 0.01 |
Plasmodium vivax | glutathione reductase, putative | 0.0677 | 1 | 1 |
Plasmodium falciparum | glutathione reductase | 0.0234 | 0.3218 | 0.3218 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.038 | 0.038 |
Schistosoma mansoni | sulfide quinone reductase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0031 | 0.01 | 0.01 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0234 | 0.3218 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.014 | 0.014 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.038 | 0.038 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0234 | 0.3218 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0062 | 0.0576 | 0.0005 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Plasmodium falciparum | thioredoxin reductase | 0.0677 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0234 | 0.3218 | 0.3218 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0062 | 0.0576 | 0.0576 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0062 | 0.0576 | 0.0005 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0062 | 0.0576 | 0.0016 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.0265 | 0.0265 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | sulfide quinone reductase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0031 | 0.01 | 0.01 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0234 | 0.3218 | 0.3218 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.184 | 0.184 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0062 | 0.0576 | 0.0016 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0031 | 0.01 | 0.01 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0062 | 0.0576 | 0.1789 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0677 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0301 | 0.0301 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0301 | 0.0301 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0564 | 0.0564 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0234 | 0.3218 | 1 |
Echinococcus granulosus | glutamate synthase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | glutamate synthase | 0.0062 | 0.0576 | 0.0576 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.0265 | 0.0265 |
Giardia lamblia | Thioredoxin reductase | 0.0062 | 0.0576 | 0.1789 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0062 | 0.0572 | 0.0572 |
Schistosoma mansoni | glutamate synthase | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0117 | 0.1415 | 0.1415 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.184 | 0.184 |
Brugia malayi | Ets-domain containing protein | 0.0072 | 0.0724 | 0.0724 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0234 | 0.3218 | 0.2807 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.038 | 0.038 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0172 | 0.2263 | 0.2263 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0062 | 0.0576 | 0.0576 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0234 | 0.3218 | 0.3218 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0062 | 0.0576 | 0.0576 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0031 | 0.01 | 0.01 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0062 | 0.0572 | 0.0572 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0062 | 0.0576 | 0.1789 |
Echinococcus granulosus | muscleblind protein | 0.0145 | 0.184 | 0.184 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0234 | 0.3218 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0062 | 0.0572 | 0.0572 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0234 | 0.3218 | 0.3218 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0062 | 0.0576 | 0.0576 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1121 | 0.1121 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0062 | 0.0576 | 0.5138 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.0265 | 0.0265 |
Schistosoma mansoni | gabp alpha | 0.0072 | 0.0724 | 0.0724 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.1121 | 0.1121 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0409 | 0.0409 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0031 | 0.01 | 0.01 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0234 | 0.3218 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0677 | 1 | 1 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.0265 | 0.0265 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0062 | 0.0576 | 0.5138 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0301 | 0.0301 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0062 | 0.0576 | 0.0576 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.0265 | 0.0822 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0234 | 0.3218 | 0.2807 |
Leishmania major | NADH dehydrogenase, putative | 0.0062 | 0.0576 | 0.0576 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0301 | 0.0301 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0031 | 0.01 | 0.01 |
Onchocerca volvulus | 0.0062 | 0.0576 | 0.5 | |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0062 | 0.0576 | 0.1789 |
Brugia malayi | jmjC domain containing protein | 0.0117 | 0.1415 | 0.1415 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0062 | 0.0576 | 0.0576 |
Schistosoma mansoni | jumonji domain containing protein | 0.0031 | 0.01 | 0.01 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0062 | 0.0576 | 0.0576 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0062 | 0.0576 | 0.1789 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0062 | 0.0576 | 0.0005 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0241 | 0.0241 |
Schistosoma mansoni | glutamate synthase | 0.0062 | 0.0576 | 0.0576 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0117 | 0.1415 | 0.1415 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | > 800 uM | Evaluated for the activation of human thrombin receptor measured by platelet aggregation | ChEMBL. | 7562949 |
EC50 (functional) | > 800 uM | Evaluated for the activation of human thrombin receptor measured by platelet aggregation | ChEMBL. | 7562949 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.