Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | nuclear receptor NHR-88 | 0.0025 | 0.0131 | 0.0131 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0062 | 0.0195 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0658 | 0.0645 |
Brugia malayi | Bromodomain containing protein | 0.008 | 0.0875 | 0.0875 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0101 | 0.115 | 0.115 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0025 | 0.0131 | 0.0117 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0203 | 0.0713 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0054 | 0.0513 | 0.0505 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0062 | 0.0055 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0062 | 0.0048 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0143 | 0.0135 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.0007 |
Brugia malayi | nuclear receptor RXR | 0.0025 | 0.0131 | 0.0131 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0222 | 0.0784 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0019 | 0.0042 | 0.0035 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0028 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0015 | 0.0025 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0026 | 0.0138 | 0.0376 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0054 | 0.0513 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0062 | 0.0062 |
Toxoplasma gondii | NAC domain-containing protein | 0.0037 | 0.0285 | 0.1023 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0054 | 0.0513 | 0.0499 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0213 | 0.2662 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.0475 | 0.0461 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0032 | 0.0025 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0028 | 0.0051 |
Echinococcus multilocularis | smad | 0.0026 | 0.0143 | 0.0129 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0026 | 0.0143 | 0.0129 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0054 | 0.0513 | 0.0505 |
Brugia malayi | steroid hormone receptor | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0213 | 0.2662 | 0.7283 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0062 | 0.0048 |
Onchocerca volvulus | 0.0054 | 0.0513 | 0.0493 | |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0062 | 0.023 |
Echinococcus multilocularis | sodium channel protein | 0.0043 | 0.0368 | 0.0354 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0203 | 0.0713 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0116 | 0.1351 | 0.5071 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0054 | 0.0513 | 0.0499 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0383 | 0.4948 | 0.4948 |
Toxoplasma gondii | hypothetical protein | 0.0019 | 0.0041 | 0.0101 |
Echinococcus multilocularis | transcription factor btf3 | 0.0037 | 0.0285 | 0.0272 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0138 | 0.0376 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0203 | 0.0196 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0025 | 0.0131 | 0.0117 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0062 | 0.0195 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.1706 | 0.1699 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0203 | 0.0189 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0015 | 0.0025 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0054 | 0.0513 | 0.0499 |
Trichomonas vaginalis | set domain proteins, putative | 0.0249 | 0.3149 | 0.8603 |
Echinococcus granulosus | Smad4 | 0.0026 | 0.0143 | 0.0129 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0222 | 0.0222 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | nuclear receptor RXR | 0.0028 | 0.0172 | 0.0172 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.0736 | 0.0722 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0061 | 0.0618 | 0.2186 |
Brugia malayi | hypothetical protein | 0.0069 | 0.0724 | 0.0724 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0129 | 0.1525 | 0.5725 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.2241 | 0.2235 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0062 | 0.0048 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0758 | 1 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0025 | 0.0131 | 0.0124 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0062 | 0.0055 |
Mycobacterium ulcerans | glutaminase | 0.0287 | 0.3656 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0062 | 0.1935 |
Schistosoma mansoni | glutaminase | 0.0287 | 0.3656 | 0.3651 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0018 | 0.0028 | 0.0014 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0054 | 0.0513 | 0.0505 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0101 | 0.115 | 0.1137 |
Loa Loa (eye worm) | glutaminase 2 | 0.0287 | 0.3656 | 0.3656 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0062 | 0.0062 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.1706 | 0.1699 |
Entamoeba histolytica | transcription factor BTF3, putative | 0.0037 | 0.0285 | 0.0859 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0791 | 0.0791 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0028 | 0.0028 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0101 | 0.115 | 0.1137 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0213 | 0.2662 | 0.7283 |
Mycobacterium ulcerans | (3R)-hydroxyacyl-ACP dehydratase subunit HadA | 0.0016 | 0.0001 | 0.0002 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0299 | 0.0285 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.0475 | 0.1781 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0026 | 0.0143 | 0.0143 |
Leishmania major | basic transcription factor 3a, putative | 0.0037 | 0.0285 | 0.0996 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0041 | 0.034 | 0.034 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0043 | 0.0368 | 0.0354 |
Brugia malayi | glutaminase DH11.1 | 0.0287 | 0.3656 | 0.3656 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0101 | 0.115 | 0.1137 |
Loa Loa (eye worm) | short chain dehydrogenase/reductase family oxidoreductase | 0.002 | 0.0061 | 0.0061 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0028 | 0.0077 |
Echinococcus multilocularis | geminin | 0.0182 | 0.2241 | 0.223 |
Loa Loa (eye worm) | DR-78 | 0.0025 | 0.0131 | 0.0131 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0026 | 0.0138 | 0.0124 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0054 | 0.0513 | 0.0499 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0022 | 0.0092 | 0.0092 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0025 | 0.0131 | 0.0131 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0061 | 0.0618 | 0.2186 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0101 | 0.115 | 0.1137 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0017 | 0.0021 | 0.0021 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0026 | 0.0138 | 0.0376 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0015 | 0.0025 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0273 | 0.0266 |
Echinococcus granulosus | zinc finger protein | 0.0022 | 0.0091 | 0.0077 |
Echinococcus granulosus | cpg binding protein | 0.0034 | 0.0247 | 0.0233 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0133 | 0.0126 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0025 | 0.0131 | 0.0117 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0285 | 0.0709 |
Onchocerca volvulus | 0.0025 | 0.0131 | 0.0111 | |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0317 | 0.0979 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | nuclear receptor | 0.0025 | 0.0131 | 0.0124 |
Schistosoma mansoni | thyroid hormone receptor | 0.0054 | 0.0513 | 0.0505 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0054 | 0.0513 | 0.0499 |
Mycobacterium ulcerans | dehydratase | 0.004 | 0.0324 | 0.0887 |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.0131 | 0.0124 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0101 | 0.115 | 0.1137 |
Brugia malayi | abnormal cell lineage protein 10 (Protein lin-10), putative | 0.0064 | 0.066 | 0.066 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0028 | 0.0074 |
Schistosoma mansoni | zinc finger protein | 0.0022 | 0.0091 | 0.0084 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.005 | 0.0463 | 0.0456 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0203 | 0.0203 |
Brugia malayi | MH1 domain containing protein | 0.0026 | 0.0143 | 0.0143 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0143 | 0.0135 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0131 | 0.0124 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0065 | 0.0668 | 0.0661 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0317 | 0.0979 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0054 | 0.0513 | 0.0513 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0247 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0203 | 0.0203 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0213 | 0.2662 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0054 | 0.0513 | 0.0505 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0026 | 0.0143 | 0.0135 |
Echinococcus granulosus | smad | 0.0026 | 0.0143 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0724 | 0.0724 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0062 | 0.017 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0083 | 0.0083 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0062 | 0.0048 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0736 | 0.0729 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0025 | 0.0131 | 0.0131 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0026 | 0.0138 | 0.0376 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.1706 | 0.1694 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0054 | 0.0513 | 0.0499 |
Brugia malayi | glutathione reductase | 0.0051 | 0.0475 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0018 | 0.0028 | 0.0014 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0116 | 0.1351 | 0.5071 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0285 | 0.0709 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0032 | 0.0025 |
Onchocerca volvulus | 0.0025 | 0.0131 | 0.0111 | |
Mycobacterium leprae | conserved hypothetical protein | 0.0213 | 0.2662 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0317 | 0.0979 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0142 | 0.1706 | 0.1706 |
Loa Loa (eye worm) | oxidoreductase | 0.0017 | 0.0021 | 0.0021 |
Toxoplasma gondii | sterol carrier protein-2 HAD-2SCP-2 | 0.0036 | 0.0269 | 0.0962 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0028 | 0.0172 | 0.0158 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0018 | 0.0028 | 0.0051 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.005 | 0.0463 | 0.045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.0197 | 0.0197 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0032 | 0.0018 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0062 | 0.0055 |
Mycobacterium tuberculosis | Probable 3-hydroxyacyl-thioester dehydratase HtdY | 0.004 | 0.0324 | 0.1215 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0083 | 0.0075 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0041 | 0.034 | 0.0333 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0172 | 0.0172 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0172 | 0.0165 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.0475 | 0.0475 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0037 | 0.0285 | 0.0996 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0028 | 0.0172 | 0.0165 |
Brugia malayi | TAR-binding protein | 0.007 | 0.0736 | 0.0736 |
Loa Loa (eye worm) | calcium channel | 0.0101 | 0.115 | 0.115 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0025 | 0.0131 | 0.0117 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.1706 | 0.1694 |
Echinococcus granulosus | transcription factor btf3 | 0.0037 | 0.0285 | 0.0272 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0028 | 0.0074 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0213 | 0.2662 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0062 | 0.0093 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0028 | 0.0074 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0017 | 0.0015 | 0.0025 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0285 | 0.0859 |
Loa Loa (eye worm) | voltage-dependent calcium channel | 0.0021 | 0.0076 | 0.0076 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0015 | 0.0007 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0018 | 0.0028 | 0.0051 |
Toxoplasma gondii | MaoC family domain-containing protein | 0.0024 | 0.0115 | 0.0378 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Onchocerca volvulus | 0.0032 | 0.0222 | 0.0202 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Mycobacterium tuberculosis | Conserved protein | 0.0026 | 0.0138 | 0.0514 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0028 | 0.0077 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0203 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Echinococcus multilocularis | cpg binding protein | 0.0034 | 0.0247 | 0.0233 |
Schistosoma mansoni | nuclear receptor | 0.0025 | 0.0131 | 0.0124 |
Schistosoma mansoni | thyroid hormone receptor | 0.0054 | 0.0513 | 0.0505 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0054 | 0.0513 | 0.0499 |
Loa Loa (eye worm) | ICD-1 protein | 0.0037 | 0.0285 | 0.0285 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0213 | 0.2662 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0116 | 0.1351 | 0.5071 |
Brugia malayi | nuclear receptor NHR-88 | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.002 | 0.0061 | 0.0225 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0116 | 0.1351 | 0.5071 |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0101 | 0.115 | 0.1143 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0213 | 0.2662 | 0.9512 |
Echinococcus multilocularis | zinc finger protein | 0.0022 | 0.0091 | 0.0077 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0054 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0015 | 0.0015 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0317 | 0.0309 |
Brugia malayi | ecdysteroid receptor | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0017 | 0.0015 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0041 | 0.0041 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.0475 | 0.1674 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0142 | 0.1706 | 0.1699 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0032 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0273 | 0.0273 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0054 | 0.0513 | 0.0513 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.0475 | 0.1738 |
Echinococcus multilocularis | peregrin | 0.0033 | 0.0237 | 0.0223 |
Brugia malayi | nuclear hormone receptor | 0.0025 | 0.0131 | 0.0131 |
Onchocerca volvulus | 0.0758 | 1 | 1 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0383 | 0.4948 | 0.4948 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0041 | 0.034 | 0.0326 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0028 | 0.0077 |
Trypanosoma brucei | transcription factor BTF3, putative | 0.0037 | 0.0285 | 0.0996 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0101 | 0.115 | 0.1137 |
Schistosoma mansoni | nuclear hormone receptor | 0.0054 | 0.0513 | 0.0505 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0101 | 0.115 | 0.1137 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0061 | 0.0609 | 0.2246 |
Schistosoma mansoni | Smad4 | 0.0026 | 0.0143 | 0.0135 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0054 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.0475 | 0.0475 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0037 | 0.0285 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Smad1 | 0.0026 | 0.0143 | 0.0143 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.005 | 0.0463 | 0.045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0025 | 0.0131 | 0.0117 |
Brugia malayi | nuclear receptor NHR-67 | 0.0025 | 0.0131 | 0.0131 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0365 | 0.0351 |
Mycobacterium ulcerans | hypothetical protein | 0.0016 | 0.0001 | 0.0002 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0025 | 0.0131 | 0.0131 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0758 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0498 | 0.0498 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0367 | 0.0367 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0142 | 0.1706 | 0.1694 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0054 | 0.0513 | 0.0513 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0026 | 0.0138 | 0.0466 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0496 | 0.0496 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Schistosoma mansoni | voltage-gated cation channel | 0.0101 | 0.115 | 0.1143 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.1141 | 0.1128 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0142 | 0.1706 | 0.1706 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0736 | 0.0729 |
Schistosoma mansoni | nuclear hormone receptor | 0.0025 | 0.0131 | 0.0124 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0062 | 0.0195 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0054 | 0.0513 | 0.0513 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0213 | 0.2662 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0026 | 0.0143 | 0.0143 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.002 | 0.0061 | 0.0166 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0054 | 0.0513 | 0.0499 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0026 | 0.0143 | 0.0129 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0143 | 0.0143 |
Brugia malayi | MH1 domain containing protein | 0.0026 | 0.0143 | 0.0143 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0198 | 0.0184 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.0015 | 0.0025 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.0475 | 0.1738 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0028 | 0.0172 | 0.0158 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.002 | 0.0061 | 0.0166 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.0197 | 0.0197 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0054 | 0.0513 | 0.0513 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0203 | 0.0713 |
Echinococcus granulosus | FTZ F1 alpha | 0.0054 | 0.0513 | 0.0499 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0054 | 0.0513 | 0.0493 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0064 | 0.0658 | 0.0645 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0054 | 0.0513 | 0.0499 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0324 | 0.0324 |
Schistosoma mansoni | transcription factor btf3 | 0.0037 | 0.0285 | 0.0278 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0054 | 0.0513 | 0.0505 |
Schistosoma mansoni | amyloid beta A4 protein related | 0.0072 | 0.0762 | 0.0755 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0041 | 0.0041 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0041 | 0.0041 |
Brugia malayi | Bromodomain containing protein | 0.0033 | 0.0237 | 0.0237 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0018 | 0.0028 | 0.0051 |
Plasmodium falciparum | basic transcription factor 3b, putative | 0.0037 | 0.0285 | 0.1023 |
Onchocerca volvulus | 0.0249 | 0.3149 | 0.3134 | |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0025 | 0.0131 | 0.0117 |
Echinococcus granulosus | peregrin | 0.0033 | 0.0237 | 0.0223 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.0864 | 0.0857 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0203 | 1 |
Echinococcus multilocularis | amyloid beta A4 protein | 0.0072 | 0.0762 | 0.0749 |
Mycobacterium ulcerans | (3R)-hydroxyacyl-ACP dehydratase subunit HadC | 0.0016 | 0.0001 | 0.0002 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0025 | 0.0131 | 0.0117 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.0736 | 0.0736 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0026 | 0.0138 | 0.0124 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0026 | 0.0143 | 0.0129 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0028 | 0.0074 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0062 | 0.0048 |
Echinococcus multilocularis | Smad4 | 0.0026 | 0.0143 | 0.0129 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0317 | 0.0303 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0025 | 0.0131 | 0.0124 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0203 | 0.0183 |
Plasmodium vivax | basic transcription factor 3b, putative | 0.0037 | 0.0285 | 0.1023 |
Loa Loa (eye worm) | X11 protein | 0.0072 | 0.0762 | 0.0762 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0301 | 0.385 | 0.385 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.0007 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0758 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0213 | 0.2662 | 1 |
Echinococcus granulosus | amyloid beta A4 protein | 0.0072 | 0.0762 | 0.0749 |
Mycobacterium ulcerans | hypothetical protein | 0.0016 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0182 | 0.2241 | 0.2235 |
Brugia malayi | MH2 domain containing protein | 0.0026 | 0.0143 | 0.0143 |
Onchocerca volvulus | 0.003 | 0.0197 | 0.0177 | |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0101 | 0.115 | 0.1137 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0054 | 0.0513 | 0.0513 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0054 | 0.0513 | 0.0499 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0365 | 0.0351 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0026 | 0.0138 | 0.0302 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0197 | 0.019 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0015 | 0.0015 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0025 | 0.0131 | 0.0111 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.0138 | 0.0376 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0223 | 0.2799 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0299 | 0.0285 |
Leishmania major | trypanothione reductase | 0.0051 | 0.0475 | 0.1674 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0025 | 0.0131 | 0.0111 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.0475 | 0.1738 |
Trypanosoma cruzi | transcription factor btf3, putative | 0.0037 | 0.0285 | 0.0996 |
Brugia malayi | MH2 domain containing protein | 0.0383 | 0.4948 | 0.4948 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0301 | 0.385 | 0.385 |
Brugia malayi | jmjC domain containing protein | 0.01 | 0.1141 | 0.1141 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0028 | 0.0074 |
Brugia malayi | RNA binding protein | 0.007 | 0.0736 | 0.0736 |
Trichomonas vaginalis | glutaminase, putative | 0.0287 | 0.3656 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0496 | 0.0496 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0054 | 0.0513 | 0.0499 |
Brugia malayi | PHD-finger family protein | 0.0028 | 0.0167 | 0.0167 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0736 | 0.0729 |
Brugia malayi | tailless protein | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0101 | 0.115 | 0.1143 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0025 | 0.0131 | 0.0124 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0062 | 0.0195 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0222 | 0.0784 |
Echinococcus granulosus | geminin | 0.0182 | 0.2241 | 0.223 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0223 | 0.2799 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0026 | 0.0143 | 0.0135 |
Loa Loa (eye worm) | Smad1 | 0.0026 | 0.0143 | 0.0143 |
Brugia malayi | beta-NAC-like protein | 0.0037 | 0.0285 | 0.0285 |
Entamoeba histolytica | hypothetical protein | 0.0213 | 0.2662 | 1 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0015 | 0.0015 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0219 | 0.2742 | 0.2742 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0014 | 0.0014 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0273 | 0.0273 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0054 | 0.0513 | 0.0513 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0025 | 0.0131 | 0.0117 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.1141 | 0.1128 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0028 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0463 | 0.0463 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0496 | 0.0496 |
Plasmodium falciparum | thioredoxin reductase | 0.0018 | 0.0028 | 0.0051 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.0736 | 0.0736 |
Mycobacterium tuberculosis | Probable reductase | 0.0116 | 0.1351 | 0.5071 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0028 | 0.0074 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.0333 | 0.0333 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0142 | 0.1706 | 0.1694 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0317 | 0.0317 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.0475 | 0.1738 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0213 | 0.2662 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0116 | 0.1351 | 0.5071 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0054 | 0.0513 | 0.0505 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0736 | 0.0729 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0054 | 0.0513 | 0.0505 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.0475 | 0.1674 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | glutaminase | 0.0287 | 0.3656 | 0.3656 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0203 | 0.0203 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.002 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0417 | 0.0417 |
Mycobacterium ulcerans | hypothetical protein | 0.004 | 0.0324 | 0.0887 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0054 | 0.0513 | 0.0499 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0054 | 0.0513 | 0.0513 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0133 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Brugia malayi | Pre-SET motif family protein | 0.0219 | 0.2742 | 0.2742 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0334 | 0.0334 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0026 | 0.0138 | 0.0466 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.0475 | 0.1738 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.0475 | 0.0461 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0025 | 0.0131 | 0.0117 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0054 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium ulcerans | hypothetical protein | 0.0016 | 0.0001 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0172 | 0.0172 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0026 | 0.0138 | 0.0514 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0062 | 0.0195 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0213 | 0.2662 | 0.9512 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.0736 | 0.0729 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0129 | 0.1525 | 0.5725 |
Brugia malayi | conserved hypotetical protein | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.115 | 0.115 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0014 | 0.0014 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0054 | 0.0513 | 0.0513 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0054 | 0.0513 | 0.0499 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0054 | 0.0513 | 0.0499 |
Schistosoma mansoni | coup transcription factor | 0.0054 | 0.0513 | 0.0505 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0101 | 0.115 | 0.1137 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0014 | 0.0007 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.0475 | 0.0475 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0062 | 0.0062 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0758 | 1 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0068 | 0.0709 | 0.0702 |
Brugia malayi | jmjC domain containing protein | 0.0041 | 0.034 | 0.034 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0054 | 0.0513 | 0.0513 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0025 | 0.0131 | 0.0117 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0026 | 0.0138 | 0.0466 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0054 | 0.0513 | 0.0505 |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.0736 | 0.0722 |
Mycobacterium tuberculosis | Probable dehydrogenase. Possible 2-enoyl acyl-CoA hydratase. | 0.004 | 0.0324 | 0.1215 |
Mycobacterium ulcerans | hypothetical protein | 0.0016 | 0.0001 | 0.0002 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0054 | 0.0513 | 0.0513 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0018 | 0.0028 | 0.0051 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0028 | 0.0074 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0025 | 0.0131 | 0.0117 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0028 | 0.0074 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0062 | 0.0195 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0054 | 0.0513 | 0.0499 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0129 | 0.1525 | 0.5725 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0213 | 0.2662 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0203 | 0.0196 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0129 | 0.1525 | 0.5725 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | maoC like domain containing protein | 0.004 | 0.0324 | 0.0324 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0021 | 0.0076 | 0.0231 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0101 | 0.115 | 0.1137 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0054 | 0.0513 | 0.0513 |
Leishmania major | hypothetical protein, conserved | 0.0223 | 0.2799 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0062 | 0.0048 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0317 | 0.0979 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0054 | 0.0513 | 0.0493 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0062 | 0.017 |
Brugia malayi | nuclear hormone receptor | 0.0054 | 0.0513 | 0.0513 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0054 | 0.0513 | 0.0505 |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.0736 | 0.0736 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0054 | 0.0513 | 0.0499 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0025 | 0.0131 | 0.0131 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0317 | 0.0309 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0025 | 0.0131 | 0.0117 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0642 | 0.0642 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.0736 | 0.0736 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0021 | 0.0076 | 0.0062 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0062 | 0.0195 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0222 | 0.0208 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0133 | 0.0119 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0317 | 0.0303 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0062 | 0.023 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0018 | 0.0028 | 0.0021 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0062 | 0.0195 |
Plasmodium falciparum | glutathione reductase | 0.0018 | 0.0028 | 0.0051 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0054 | 0.0513 | 0.0513 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0054 | 0.0513 | 0.0513 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0131 | 0.0131 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.029 | 0.0276 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0116 | 0.1351 | 0.5071 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0026 | 0.0143 | 0.0129 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0222 | 0.0215 |
Brugia malayi | ecdysone receptor | 0.0025 | 0.0131 | 0.0131 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0028 | 0.0172 | 0.0172 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.0247 | 0.024 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0513 | 0.0513 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0223 | 0.2799 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0222 | 0.0215 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0203 | 0.0713 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0041 | 0.034 | 0.0333 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.005 | 0.0463 | 0.0456 |
Schistosoma mansoni | smad | 0.0026 | 0.0143 | 0.0135 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0054 | 0.0513 | 0.0499 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0062 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0076 | 0.0076 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0062 | 0.0093 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0496 | 0.0496 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 14.4 mg kg-1 | Anticonvulsant activity against maximal electroshock-induced seizures in Wistar rats following i.p. administration. | ChEMBL. | 7562950 |
ED50 (functional) | > 25 mg kg-1 | Anticonvulsant activity against maximal electroshock-induced seizures in Wistar rats following p.o. administration. | ChEMBL. | 7562950 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.