Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Dihydrofolate reductase | 0.5541 | 0.7153 | 0.9911 |
Brugia malayi | Bromodomain containing protein | 0.0043 | 0.0028 | 0.0025 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Entamoeba histolytica | hypothetical protein | 0.0333 | 0.0404 | 1 |
Trypanosoma brucei | ubiquitin-protein ligase, putative | 0.004 | 0.0025 | 0.002 |
Brugia malayi | thymidylate synthase | 0.5591 | 0.7217 | 1 |
Mycobacterium tuberculosis | Probable thymidylate synthase ThyA (ts) (TSASE) | 0.5591 | 0.7217 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.008 | 0.0077 | 0.0106 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0029 | 0.0007 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0041 | 0.0026 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.004 | 0.0056 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase | 0.7738 | 1 | 1 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0028 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.1143 | 0.1453 | 0.2014 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0029 | 0.0011 | 0.0012 |
Echinococcus granulosus | dnaJ subfamily B | 0.0835 | 0.1055 | 0.1459 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0333 | 0.0404 | 0.0557 |
Schistosoma mansoni | sodium/solute symporter | 0.0076 | 0.0071 | 0.0098 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0042 | 0.0058 |
Schistosoma mansoni | alpha glucosidase | 0.0038 | 0.0022 | 0.003 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.1143 | 0.1453 | 0.2014 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0617 | 0.0773 | 0.107 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0028 | 1 |
Onchocerca volvulus | 0.5591 | 0.7217 | 1 | |
Brugia malayi | beta-lactamase | 0.0106 | 0.0111 | 0.014 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0106 | 0.0111 | 0.0153 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0099 | 0.0102 | 0.242 |
Schistosoma mansoni | inositol transporter | 0.0076 | 0.0071 | 0.0098 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0106 | 0.0111 | 0.0146 |
Leishmania major | selenophosphate synthetase, putative | 0.0105 | 0.0109 | 0.0105 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0037 | 0.0021 | 0.003 |
Brugia malayi | hypothetical protein | 0.266 | 0.3419 | 0.473 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0022 | 0.0001 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Echinococcus multilocularis | folylpolyglutamate synthase, mitochondrial | 0.042 | 0.0517 | 0.061 |
Trypanosoma brucei | Selenophosphate synthetase 2 | 0.0105 | 0.0109 | 0.0105 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1044 | 0.1326 | 0.3838 |
Echinococcus multilocularis | cpg binding protein | 0.0095 | 0.0095 | 0.011 |
Leishmania major | hypothetical protein, conserved | 0.0051 | 0.0039 | 0.0034 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0051 | 0.0039 | 0.0047 |
Brugia malayi | Smad1 | 0.0091 | 0.0091 | 0.0112 |
Mycobacterium ulcerans | methionyl-tRNA formyltransferase | 0.0051 | 0.0039 | 0.0047 |
Echinococcus granulosus | expressed conserved protein | 0.0093 | 0.0094 | 0.0127 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0054 | 0.0075 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.002 | 0.0025 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0022 | 0.0002 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0679 | 0.0853 | 0.1176 |
Schistosoma mansoni | hypothetical protein | 0.0362 | 0.0441 | 0.0611 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0031 | 0.0013 | 0.0004 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0033 | 0.0036 |
Plasmodium vivax | methionyl-tRNA formyltransferase, putative | 0.0051 | 0.0039 | 0.0034 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0051 | 0.0039 | 0.0034 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0328 | 0.0397 | 0.055 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0038 | 0.0053 |
Mycobacterium ulcerans | hypothetical protein | 0.0106 | 0.0111 | 0.0146 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0028 | 0.0023 |
Toxoplasma gondii | ubiquitin-conjugating enzyme subfamily protein | 0.004 | 0.0025 | 0.002 |
Echinococcus multilocularis | GPCR, family 2 | 0.0362 | 0.0441 | 0.0521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0039 | 0.0034 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0106 | 0.0111 | 0.0263 |
Mycobacterium tuberculosis | Probable phosphoribosylformylglycinamidine CYCLO-ligase PurM (AIRS) (phosphoribosyl-aminoimidazole synthetase) (air synthase) | 0.0311 | 0.0376 | 0.0515 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0171 | 0.0195 | 0.0266 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0051 | 0.0039 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0041 | 0.0056 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0042 | 0.0058 |
Plasmodium falciparum | selenide water dikinase, putative | 0.0105 | 0.0109 | 0.0105 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0058 | 0.0048 | 0.0043 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0026 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0026 | 0.0035 |
Echinococcus granulosus | Smad4 | 0.0091 | 0.0091 | 0.0123 |
Brugia malayi | Importin beta-1 subunit | 0.0058 | 0.0048 | 0.0053 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0037 | 0.0021 | 0.0016 |
Brugia malayi | hypothetical protein | 0.0051 | 0.0039 | 0.004 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0066 | 0.0092 |
Schistosoma mansoni | ran | 0.0043 | 0.0028 | 0.0039 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0041 | 0.0026 | 0.0027 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0328 | 0.0397 | 0.055 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0088 | 0.0087 | 0.0118 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0058 | 0.0048 | 0.0043 |
Echinococcus granulosus | folylpolyglutamate synthase mitochondrial | 0.042 | 0.0517 | 0.0713 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0362 | 0.0441 | 0.0599 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0028 | 0.002 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0042 | 0.0045 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0328 | 0.0397 | 0.0547 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0171 | 0.0195 | 0.0228 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0051 | 0.0039 | 0.0034 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0054 | 0.0075 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0076 | 0.0071 | 0.0095 |
Plasmodium falciparum | ubiquitin-conjugating enzyme E2 N, putative | 0.004 | 0.0025 | 0.002 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.004 | 0.0025 | 0.001 |
Onchocerca volvulus | 0.0106 | 0.0111 | 0.0118 | |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0307 | 0.037 | 0.0365 |
Wolbachia endosymbiont of Brugia malayi | phosphoribosylamine--glycine ligase | 0.1411 | 0.1801 | 1 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0028 | 0.0023 |
Schistosoma mansoni | cpg binding protein | 0.0095 | 0.0095 | 0.0132 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0029 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0006 | 0.0008 |
Brugia malayi | N-terminal motif family protein | 0.0194 | 0.0224 | 0.0297 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0037 | 0.0021 | 0.0409 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0054 | 0.0061 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0022 | 0.0001 | 0.0001 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0058 | 0.0048 | 0.0054 |
Schistosoma mansoni | importin beta-1 | 0.0058 | 0.0048 | 0.0066 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1044 | 0.1326 | 0.1837 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.0087 | 0.0121 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0037 | 0.0021 | 0.0016 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.005 | 0.007 |
Leishmania major | GTP-binding protein, putative | 0.0043 | 0.0028 | 0.0023 |
Onchocerca volvulus | 0.0088 | 0.0086 | 0.0085 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0051 | 0.0039 | 0.0034 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0054 | 0.0061 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0101 | 0.0104 | 0.0144 |
Schistosoma mansoni | smad | 0.0041 | 0.0026 | 0.0035 |
Loa Loa (eye worm) | thymidylate synthase | 0.5591 | 0.7217 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0328 | 0.0397 | 0.0537 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0781 | 0.0985 | 0.1353 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0091 | 0.0091 | 0.0105 |
Mycobacterium ulcerans | lipase LipD | 0.0106 | 0.0111 | 0.0146 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0028 | 0.0039 |
Brugia malayi | follicle stimulating hormone receptor | 0.0239 | 0.0283 | 0.0379 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0028 | 0.0036 |
Echinococcus multilocularis | geminin | 0.1204 | 0.1532 | 0.1815 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0362 | 0.0441 | 0.0611 |
Mycobacterium tuberculosis | Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) | 0.042 | 0.0517 | 0.071 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0362 | 0.0441 | 0.0521 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.008 | 0.0077 | 0.0106 |
Mycobacterium tuberculosis | Probable phosphoribosylamine--glycine ligase PurD (GARS) (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synt | 0.0206 | 0.024 | 0.0325 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.004 | 0.0025 | 0.0003 |
Trichomonas vaginalis | ran, putative | 0.0043 | 0.0028 | 0.0019 |
Loa Loa (eye worm) | Smad1 | 0.0091 | 0.0091 | 0.0126 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0054 | 0.0075 |
Mycobacterium ulcerans | dihydrofolate reductase DfrA | 0.5541 | 0.7153 | 0.9911 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0171 | 0.0195 | 0.0228 |
Onchocerca volvulus | 0.0248 | 0.0294 | 0.0374 | |
Schistosoma mansoni | high-affinity choline transporter | 0.0686 | 0.0861 | 0.1194 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.1337 | 0.1706 | 0.2363 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0031 | 0.0043 |
Trypanosoma cruzi | selenophosphate synthetase, putative | 0.0105 | 0.0109 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 0.0368 | 0.051 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0015 | 0.0008 |
Entamoeba histolytica | hypothetical protein | 0.0333 | 0.0404 | 1 |
Trypanosoma cruzi | methionyl-tRNA formyltransferase, putative | 0.0051 | 0.0039 | 0.0018 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0091 | 0.0091 | 0.0126 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0042 | 0.0055 |
Schistosoma mansoni | smad | 0.0091 | 0.0091 | 0.0126 |
Echinococcus granulosus | ubiquitin conjugating enzyme E2 N | 0.004 | 0.0025 | 0.0031 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0063 | 0.0054 | 0.0061 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0043 | 0.0028 | 0.0023 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0028 | 0.0025 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0091 | 0.0091 | 0.0123 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0038 | 0.0022 | 0.0017 |
Brugia malayi | MH1 domain containing protein | 0.0091 | 0.0091 | 0.0112 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0041 | 0.0026 | 0.0032 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1044 | 0.1326 | 0.3838 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0106 | 0.0111 | 0.0106 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0041 | 0.0026 | 0.0035 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0022 | 0.0001 |
Onchocerca volvulus | 0.0305 | 0.0368 | 0.0477 | |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0111 | 0.0153 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0022 | 0.0002 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0049 | 0.0064 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0152 | 0.017 | 0.0235 |
Brugia malayi | MH1 domain containing protein | 0.005 | 0.0038 | 0.0039 |
Trypanosoma cruzi | dihydrofolate reductase-thymidylate synthase, putative | 0.266 | 0.3419 | 0.3405 |
Onchocerca volvulus | 0.0485 | 0.0601 | 0.0801 | |
Schistosoma mansoni | hypothetical protein | 0.0781 | 0.0985 | 0.1365 |
Leishmania major | hypothetical protein, conserved | 0.0106 | 0.0111 | 0.0106 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0029 | 0.0007 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Trypanosoma cruzi | selenophosphate synthetase, putative | 0.0105 | 0.0109 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0023 | 0.0032 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0106 | 0.0111 | 0.0146 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.005 | 0.0067 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.6527 | 0.843 | 1 |
Toxoplasma gondii | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7738 | 1 | 1 |
Plasmodium vivax | importin-beta 2, putative | 0.0058 | 0.0048 | 0.0043 |
Schistosoma mansoni | smad1 5 8 and | 0.0091 | 0.0091 | 0.0126 |
Onchocerca volvulus | 0.0106 | 0.0111 | 0.0118 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0328 | 0.0397 | 0.055 |
Toxoplasma gondii | exonuclease III APE | 0.0037 | 0.0021 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0111 | 0.0153 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0042 | 0.0047 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0042 | 0.0058 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0106 | 0.0111 | 0.0146 |
Plasmodium vivax | SET domain protein, putative | 0.0063 | 0.0054 | 0.0049 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0038 | 0.0022 | 0.003 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0076 | 0.0071 | 0.0081 |
Schistosoma mansoni | cpg binding protein | 0.0095 | 0.0095 | 0.0132 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0042 | 0.0045 |
Brugia malayi | PHD-finger family protein | 0.0034 | 0.0017 | 0.001 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0106 | 0.0111 | 0.0146 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0039 | 0.0017 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.0404 | 0.056 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0333 | 0.0404 | 0.056 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0054 | 0.0072 |
Schistosoma mansoni | hypothetical protein | 0.0362 | 0.0441 | 0.0611 |
Brugia malayi | GH02984p | 0.0686 | 0.0861 | 0.1182 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0307 | 0.037 | 0.035 |
Loa Loa (eye worm) | nuclear factor I | 0.005 | 0.0038 | 0.0053 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0028 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.0362 | 0.0441 | 0.0611 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0006 | 0.0004 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0054 | 0.0075 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0029 | 0.001 | 0.0014 |
Mycobacterium ulcerans | phosphoribosylaminoimidazole synthetase | 0.0311 | 0.0376 | 0.0515 |
Mycobacterium leprae | PROBABLE THIAMINE-MONOPHOSPHATE KINASE THIL (THIAMINE-PHOSPHATE KINASE) | 0.0063 | 0.0055 | 0.0069 |
Trichomonas vaginalis | conserved hypothetical protein | 0.266 | 0.3419 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0088 | 0.0086 | 0.0106 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0091 | 0.0091 | 0.0105 |
Leishmania major | ubiquitin-conjugating enzyme e2, putative | 0.004 | 0.0025 | 0.002 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.0161 | 0.014 |
Loa Loa (eye worm) | selenium donor protein | 0.0105 | 0.0109 | 0.0152 |
Toxoplasma gondii | formyl transferase domain-containing protein | 0.0051 | 0.0039 | 0.0034 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0362 | 0.0441 | 0.0608 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0039 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0048 | 0.0066 |
Brugia malayi | Pre-SET motif family protein | 0.0063 | 0.0054 | 0.0062 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.0063 | 0.0072 |
Brugia malayi | MH2 domain containing protein | 0.0091 | 0.0091 | 0.0112 |
Brugia malayi | ubiquitin conjugating enzyme protein 13 | 0.004 | 0.0025 | 0.0021 |
Onchocerca volvulus | 0.0076 | 0.0071 | 0.0063 | |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0042 | 0.0055 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0022 | 0.0002 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1044 | 0.1326 | 0.3838 |
Echinococcus granulosus | cpg binding protein | 0.0095 | 0.0095 | 0.0129 |
Brugia malayi | selenium donor protein | 0.0105 | 0.0109 | 0.0138 |
Brugia malayi | MH2 domain containing protein | 0.1337 | 0.1706 | 0.2353 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0022 | 0.0002 |
Plasmodium falciparum | importin beta, putative | 0.0058 | 0.0048 | 0.0043 |
Mycobacterium tuberculosis | Phosphoribosylformylglycinamidine synthase II PurL (FGAM synthase II) | 0.0105 | 0.0109 | 0.0145 |
Trypanosoma cruzi | methionyl-tRNA formyltransferase, putative | 0.0051 | 0.0039 | 0.0018 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0722 | 0.0908 | 0.261 |
Trypanosoma brucei | glucosidase, putative | 0.0038 | 0.0022 | 0.0017 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0106 | 0.0111 | 0.0146 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0333 | 0.0404 | 0.0477 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0054 | 0.0075 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1044 | 0.1326 | 0.3838 |
Echinococcus granulosus | lamin | 0.0053 | 0.0042 | 0.0055 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0046 | 0.0033 | 0.0042 |
Onchocerca volvulus | Putative folylpolyglutamate synthase | 0.042 | 0.0517 | 0.0683 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0076 | 0.0071 | 0.0095 |
Plasmodium vivax | dihydrofolate synthase/folylpolyglutamate synthase, putative | 0.042 | 0.0517 | 0.0512 |
Plasmodium vivax | hypothetical protein, conserved | 0.0106 | 0.0111 | 0.0106 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0099 | 0.0102 | 0.0127 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0076 | 0.0071 | 0.0081 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0024 | 0.0004 | 0.0005 |
Brugia malayi | Sodium:solute symporter family protein | 0.0076 | 0.0071 | 0.0085 |
Brugia malayi | beta-lactamase family protein | 0.0106 | 0.0111 | 0.014 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0022 | 0.0426 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0037 | 0.0021 | 0.0023 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0106 | 0.0111 | 0.0263 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0051 | 0.0039 | 0.0017 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0046 | 0.0033 | 0.0034 |
Loa Loa (eye worm) | histone methyltransferase | 0.0029 | 0.0011 | 0.0015 |
Trichomonas vaginalis | ubiquitin-conjugating enzyme E2, putative | 0.004 | 0.0025 | 0.001 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0088 | 0.0087 | 0.0121 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0152 | 0.017 | 0.0222 |
Trichomonas vaginalis | esterase, putative | 0.0106 | 0.0111 | 0.0263 |
Leishmania major | methionyl-tRNA formyltransferase, putative | 0.0051 | 0.0039 | 0.0034 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.004 | 0.0025 | 0.002 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0038 | 0.0022 | 0.0023 |
Brugia malayi | MH1 domain containing protein | 0.005 | 0.0038 | 0.0039 |
Plasmodium vivax | selenophosphate synthetase, putative | 0.0105 | 0.0109 | 0.0105 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0037 | 0.0021 | 0.0023 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0038 | 0.0022 | 0.0002 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0022 | 0.0426 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0041 | 0.0026 | 0.0032 |
Schistosoma mansoni | ran | 0.0043 | 0.0028 | 0.0039 |
Schistosoma mansoni | hypothetical protein | 0.1204 | 0.1532 | 0.2123 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1044 | 0.1326 | 0.1825 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0026 | 0.0036 |
Echinococcus granulosus | selenide water dikinase | 0.0105 | 0.0109 | 0.0148 |
Treponema pallidum | methionyl-tRNA formyltransferase (fmt) | 0.0051 | 0.0039 | 0.0667 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0685 | 0.086 | 0.1161 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0029 | 0.0011 | 0.001 |
Mycobacterium tuberculosis | Hypothetical protein | 0.266 | 0.3419 | 0.4734 |
Brugia malayi | FolC bifunctional protein | 0.042 | 0.0517 | 0.0703 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0038 | 0.0022 | 0.0002 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.002 | 0.0021 |
Mycobacterium ulcerans | phosphoribosylglycinamide formyltransferase | 0.0051 | 0.0039 | 0.0047 |
Trypanosoma brucei | dihydrofolate reductase-thymidylate synthase | 0.7738 | 1 | 1 |
Echinococcus multilocularis | thymidylate synthase | 0.5591 | 0.7217 | 0.8561 |
Mycobacterium leprae | PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) | 0.042 | 0.0517 | 0.071 |
Echinococcus multilocularis | 0.0105 | 0.0109 | 0.0127 | |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0041 | 0.0026 | 0.0027 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0088 | 0.0086 | 0.012 |
Plasmodium falciparum | methionyl-tRNA formyltransferase, putative | 0.0051 | 0.0039 | 0.0034 |
Mycobacterium leprae | Probable lipase LipE | 0.0106 | 0.0111 | 0.0146 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0063 | 0.0054 | 0.0075 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0043 | 0.0028 | 0.0039 |
Echinococcus multilocularis | ubiquitin conjugating enzyme E2 N | 0.004 | 0.0025 | 0.0027 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.005 | 0.0063 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.005 | 0.007 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0038 | 0.0022 | 0.0017 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.005 | 0.0063 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0043 | 0.0028 | 0.0023 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0088 | 0.0087 | 0.0107 |
Schistosoma mansoni | bromodomain containing protein | 0.0073 | 0.0068 | 0.0094 |
Loa Loa (eye worm) | beta-lactamase | 0.0106 | 0.0111 | 0.0153 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0171 | 0.0195 | 0.0256 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0194 | 0.0224 | 0.0275 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.004 | 0.0025 | 0.0034 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0076 | 0.0071 | 0.0066 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0686 | 0.0861 | 0.1191 |
Onchocerca volvulus | 0.0088 | 0.0087 | 0.0086 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0054 | 0.0061 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.1143 | 0.1453 | 0.2003 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0038 | 0.0022 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0362 | 0.0441 | 0.0611 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0037 | 0.0021 | 0.0016 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0024 | 0.0004 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0617 | 0.0773 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.004 | 0.0056 |
Schistosoma mansoni | folylpolyglutamate synthase | 0.042 | 0.0517 | 0.0716 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0076 | 0.0071 | 0.0081 |
Brugia malayi | hypothetical protein | 0.0305 | 0.0368 | 0.0498 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0106 | 0.0111 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0028 | 0.0039 |
Echinococcus granulosus | thymidylate synthase | 0.5591 | 0.7217 | 1 |
Trypanosoma cruzi | folylpolyglutamate synthetase | 0.042 | 0.0517 | 0.0497 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0026 | 0.0036 |
Brugia malayi | Pre-SET motif family protein | 0.0426 | 0.0525 | 0.0715 |
Schistosoma mansoni | bifunctional dihydrofolate reductase-thymidylate synthase | 0.5591 | 0.7217 | 1 |
Mycobacterium ulcerans | thymidylate synthase | 0.5591 | 0.7217 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0099 | 0.0102 | 0.0118 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0106 | 0.0111 | 0.0153 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.005 | 0.0063 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0106 | 0.0111 | 0.0146 |
Schistosoma mansoni | selinide water dikinase | 0.0105 | 0.0109 | 0.0152 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0037 | 0.0021 | 0.0022 |
Mycobacterium tuberculosis | Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) | 0.5541 | 0.7153 | 0.9911 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0142 | 0.0157 | 0.0214 |
Onchocerca volvulus | 0.0063 | 0.0054 | 0.004 | |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0426 | 0.0525 | 0.0728 |
Chlamydia trachomatis | methionyl tRNAformyltransferase | 0.0051 | 0.0039 | 0.0048 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0041 | 0.0026 | 0.0022 |
Leishmania major | pteridine reductase 1 | 0.0208 | 0.0242 | 0.0237 |
Echinococcus multilocularis | expressed conserved protein | 0.0093 | 0.0094 | 0.0109 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0038 | 0.0022 | 0.0017 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0037 | 0.0021 | 0.0016 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0028 | 0.0009 | 0.0012 |
Echinococcus multilocularis | dihydrofolate reductase | 0.5541 | 0.7153 | 0.8485 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0038 | 0.0022 | 0.0027 |
Mycobacterium ulcerans | phosphoribosylamine--glycine ligase | 0.1411 | 0.1801 | 0.249 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0099 | 0.0102 | 0.0138 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0063 | 0.0054 | 0.0075 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.005 | 0.0063 |
Schistosoma mansoni | dihydrofolate reductase | 0.5541 | 0.7153 | 0.9911 |
Echinococcus granulosus | geminin | 0.1204 | 0.1532 | 0.2121 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0091 | 0.0091 | 0.0123 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0028 | 0.0007 |
Mycobacterium tuberculosis | Probable formyltetrahydrofolate deformylase PurU (formyl-FH(4) hydrolase) | 0.0051 | 0.0039 | 0.0047 |
Wolbachia endosymbiont of Brugia malayi | methionyl-tRNA formyltransferase | 0.0051 | 0.0039 | 0.019 |
Treponema pallidum | folylpolyglutamate synthetase (folC) | 0.042 | 0.0517 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.1143 | 0.1453 | 0.2003 |
Schistosoma mansoni | alpha-glucosidase | 0.0147 | 0.0164 | 0.0227 |
Trichomonas vaginalis | set domain proteins, putative | 0.0485 | 0.0601 | 0.1707 |
Echinococcus multilocularis | snurportin 1 | 0.0617 | 0.0773 | 0.0914 |
Echinococcus multilocularis | solute carrier family 5 | 0.0076 | 0.0071 | 0.0081 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0106 | 0.0111 | 0.0146 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0063 | 0.0054 | 0.0049 |
Schistosoma mansoni | alpha-glucosidase | 0.0147 | 0.0164 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0111 | 0.0153 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1044 | 0.1326 | 0.3838 |
Plasmodium vivax | bifunctional dihydrofolate reductase-thymidylate synthase, putative | 0.7738 | 1 | 1 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0106 | 0.0111 | 0.0146 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0002 | 0.0003 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0046 | 0.0033 | 0.0028 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0042 | 0.0058 |
Schistosoma mansoni | zinc finger protein | 0.0029 | 0.001 | 0.0014 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0046 | 0.0033 | 0.0034 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0022 | 0.0002 |
Brugia malayi | Bromodomain containing protein | 0.0085 | 0.0083 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0071 | 0.0098 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0054 | 0.0061 |
Onchocerca volvulus | 0.0311 | 0.0376 | 0.0488 | |
Schistosoma mansoni | inositol transporter | 0.0076 | 0.0071 | 0.0098 |
Entamoeba histolytica | hypothetical protein | 0.0047 | 0.0033 | 0.0715 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0054 | 0.0075 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.1337 | 0.1706 | 0.2363 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0028 | 0.0009 | 0.0009 |
Entamoeba histolytica | hypothetical protein | 0.0333 | 0.0404 | 1 |
Brugia malayi | Ubiquitin conjugating enzyme protein 13 | 0.004 | 0.0025 | 0.0021 |
Trichomonas vaginalis | importin beta-1, putative | 0.0047 | 0.0033 | 0.0036 |
Schistosoma mansoni | Smad4 | 0.0041 | 0.0026 | 0.0035 |
Echinococcus granulosus | folylpolyglutamate synthase, mitochondrial | 0.042 | 0.0517 | 0.0713 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0029 | 0.0007 |
Echinococcus granulosus | zinc finger transcription factor gli2 | 0.0307 | 0.0371 | 0.0511 |
Mycobacterium ulcerans | phosphoribosylformylglycinamidine synthase II | 0.0105 | 0.0109 | 0.0145 |
Brugia malayi | beta-lactamase family protein | 0.0106 | 0.0111 | 0.014 |
Echinococcus multilocularis | zinc finger transcription factor gli2 | 0.0307 | 0.0371 | 0.0437 |
Schistosoma mansoni | ap endonuclease | 0.0037 | 0.0021 | 0.003 |
Loa Loa (eye worm) | acetyltransferase | 0.0152 | 0.017 | 0.0235 |
Loa Loa (eye worm) | hypothetical protein | 0.0362 | 0.0441 | 0.0611 |
Mycobacterium leprae | PROBABLE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE CYCLO-LIGASE PURM (AIRS) (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE) (AIR SYNTHASE) | 0.0311 | 0.0376 | 0.0515 |
Echinococcus multilocularis | smad | 0.0091 | 0.0091 | 0.0105 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0152 | 0.017 | 0.0199 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0088 | 0.0087 | 0.0101 |
Leishmania major | importin beta-1 subunit, putative | 0.0047 | 0.0033 | 0.0029 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0076 | 0.0071 | 0.0095 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0106 | 0.0111 | 0.015 |
Trichomonas vaginalis | dihydrofolate synthase/folylpolyglutamate synthase, putative | 0.042 | 0.0517 | 0.1458 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.008 | 0.0077 | 0.0103 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0042 | 0.0047 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0037 | 0.0021 | 0.0091 |
Toxoplasma gondii | bifunctional protein FolC subfamily protein | 0.042 | 0.0517 | 0.0512 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0091 | 0.0091 | 0.0126 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0005 | 0.0007 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0024 | 0.0004 | 0.0002 |
Plasmodium falciparum | dihydrofolate synthase/folylpolyglutamate synthase | 0.042 | 0.0517 | 0.0512 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0058 | 0.0048 | 0.0043 |
Schistosoma mansoni | smad1 5 8 and | 0.0091 | 0.0091 | 0.0126 |
Loa Loa (eye worm) | dihydrofolate reductase | 0.5541 | 0.7153 | 0.9911 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.0102 | 0.0141 |
Schistosoma mansoni | ubiquitin conjugating enzyme 13 | 0.004 | 0.0025 | 0.0034 |
Echinococcus granulosus | smad | 0.0091 | 0.0091 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0026 | 0.0036 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0036 | 0.004 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 0.0111 | 0.0089 |
Brugia malayi | hypothetical protein | 0.0333 | 0.0404 | 0.0548 |
Loa Loa (eye worm) | hypothetical protein | 0.0781 | 0.0985 | 0.1365 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0091 | 0.0091 | 0.0126 |
Schistosoma mansoni | hypothetical protein | 0.1204 | 0.1532 | 0.2123 |
Schistosoma mansoni | hypothetical protein | 0.0835 | 0.1055 | 0.1462 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0174 | 0.0199 | 0.0194 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0043 | 0.0028 | 0.0007 |
Entamoeba histolytica | ubiquitin-conjugating enzyme family protein | 0.004 | 0.0025 | 0.0496 |
Schistosoma mansoni | methionyl-tRNA formyltransferase | 0.0051 | 0.0039 | 0.0054 |
Toxoplasma gondii | selenide, water dikinase | 0.0105 | 0.0109 | 0.0105 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0042 | 0.0047 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.0182 | 0.0246 |
Trypanosoma brucei | folylpolyglutamate synthase, putative | 0.042 | 0.0517 | 0.0512 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0328 | 0.0397 | 0.0468 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.0224 | 0.031 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0043 | 0.0028 | 0.0035 |
Trypanosoma brucei | pteridine reductase 1 | 0.0205 | 0.0239 | 0.0234 |
Mycobacterium leprae | PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE II PURL (FGAM SYNTHASE II) | 0.0105 | 0.0109 | 0.0145 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0046 | 0.0033 | 0.0028 |
Echinococcus granulosus | zinc finger protein | 0.0029 | 0.001 | 0.001 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0006 | 0.0005 |
Brugia malayi | dihydrofolate reductase family protein | 0.5541 | 0.7153 | 0.9911 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0142 | 0.0157 | 0.0183 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.0077 | 0.0106 |
Schistosoma mansoni | smad1 5 8 and | 0.0091 | 0.0091 | 0.0126 |
Schistosoma mansoni | lamin | 0.0053 | 0.0042 | 0.0058 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.0063 | 0.0084 |
Loa Loa (eye worm) | hypothetical protein | 0.0686 | 0.0861 | 0.1194 |
Onchocerca volvulus | 0.0099 | 0.0101 | 0.0105 | |
Echinococcus granulosus | importin subunit beta 1 | 0.0058 | 0.0048 | 0.0063 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0145 | 0.0161 | 0.0156 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0188 | 0.0217 | 0.03 |
Loa Loa (eye worm) | ubiquitin conjugating enzyme protein 13 | 0.004 | 0.0025 | 0.0034 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0047 | 0.0033 | 0.0036 |
Trypanosoma cruzi | ubiquitin-conjugating enzyme E2, putative | 0.004 | 0.0025 | 0.0003 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0028 | 0.0031 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0106 | 0.0111 | 0.0263 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.005 | 0.0046 |
Brugia malayi | MH1 domain containing protein | 0.0091 | 0.0091 | 0.0112 |
Onchocerca volvulus | 0.0042 | 0.0027 | 0.0003 | |
Trypanosoma cruzi | folylpolyglutamate synthase, putative | 0.042 | 0.0517 | 0.0497 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0047 | 0.0033 | 0.0012 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0362 | 0.0441 | 0.0521 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0041 | 0.002 |
Onchocerca volvulus | 0.0106 | 0.0111 | 0.0118 | |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0028 | 0.0036 |
Toxoplasma gondii | hypothetical protein | 0.0049 | 0.0037 | 0.0032 |
Brugia malayi | MH2 domain containing protein | 0.0041 | 0.0026 | 0.0022 |
Brugia malayi | RNA, U transporter 1 | 0.0164 | 0.0186 | 0.0244 |
Mycobacterium ulcerans | thiamine monophosphate kinase | 0.0063 | 0.0055 | 0.0069 |
Toxoplasma gondii | ABC1 family protein | 0.0106 | 0.0111 | 0.0106 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0106 | 0.0111 | 0.0263 |
Echinococcus multilocularis | Smad4 | 0.0091 | 0.0091 | 0.0105 |
Brugia malayi | MH2 domain containing protein | 0.0091 | 0.0091 | 0.0112 |
Echinococcus granulosus | dihydrofolate reductase | 0.5541 | 0.7153 | 0.9911 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0239 | 0.0283 | 0.0392 |
Schistosoma mansoni | Smad4 | 0.0091 | 0.0091 | 0.0126 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1044 | 0.1326 | 0.3838 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.008 | 0.0077 | 0.0088 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0106 | 0.0111 | 0.014 |
Plasmodium vivax | ubiquitin-conjugating enzyme E2 N, putative | 0.004 | 0.0025 | 0.002 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0686 | 0.0861 | 0.1019 |
Echinococcus multilocularis | folylpolyglutamate synthase, mitochondrial | 0.042 | 0.0517 | 0.061 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0106 | 0.0111 | 0.0128 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.004 | 0.0025 | 0.0502 |
Mycobacterium ulcerans | beta-lactamase | 0.0106 | 0.0111 | 0.0146 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.004 | 0.0025 | 0.5591 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.005 | 0.0046 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0106 | 0.0111 | 0.0089 |
Schistosoma mansoni | lamin | 0.0053 | 0.0042 | 0.0058 |
Mycobacterium leprae | DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) | 0.5541 | 0.7153 | 0.9911 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0076 | 0.0071 | 0.0095 |
Loa Loa (eye worm) | zinc finger protein | 0.0307 | 0.0371 | 0.0514 |
Onchocerca volvulus | 0.0053 | 0.0042 | 0.0023 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0162 | 0.0182 | 0.0246 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0307 | 0.037 | 0.0365 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0024 | 0.0004 | 0.0002 |
Mycobacterium leprae | conserved hypothetical protein | 0.0106 | 0.0111 | 0.0146 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0028 | 0.0025 |
Schistosoma mansoni | cpg binding protein | 0.0088 | 0.0086 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0111 | 0.0153 |
Mycobacterium leprae | PROBABLE THYMIDYLATE SYNTHASE THYA (TS) (TSASE) | 0.5591 | 0.7217 | 1 |
Trypanosoma brucei | methionyl-tRNA formyltransferase | 0.0051 | 0.0039 | 0.0034 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0106 | 0.0111 | 0.0146 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0328 | 0.0397 | 0.055 |
Loa Loa (eye worm) | FolC protein | 0.042 | 0.0517 | 0.0716 |
Wolbachia endosymbiont of Brugia malayi | phosphoribosylaminoimidazole synthetase | 0.0311 | 0.0376 | 0.2068 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0722 | 0.0908 | 0.261 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0024 | 0.0004 | 0.0002 |
Chlamydia trachomatis | dihydrofolate reductase | 0.5541 | 0.7153 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0106 | 0.0111 | 0.0146 |
Wolbachia endosymbiont of Brugia malayi | phosphoribosylformylglycinamidine synthase domain-containing protein | 0.0105 | 0.0109 | 0.0582 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0835 | 0.1055 | 0.1249 |
Onchocerca volvulus | 0.0053 | 0.0042 | 0.0023 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0005 | 0.0007 |
Mycobacterium ulcerans | folylpolyglutamate synthase protein FolC | 0.042 | 0.0517 | 0.071 |
Echinococcus granulosus | GPCR family 2 | 0.0362 | 0.0441 | 0.0608 |
Mycobacterium leprae | PROBABLE PHOSPHORIBOSYLAMINE--GLYCINE LIGASE PURD (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNT | 0.1411 | 0.1801 | 0.249 |
Entamoeba histolytica | Ran family GTPase | 0.0043 | 0.0028 | 0.0574 |
Echinococcus granulosus | solute carrier family 5 | 0.0076 | 0.0071 | 0.0095 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0054 | 0.0075 |
Schistosoma mansoni | ap endonuclease | 0.0037 | 0.0021 | 0.003 |
Entamoeba histolytica | hypothetical protein | 0.0333 | 0.0404 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0171 | 0.0195 | 0.027 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.005 | 0.0057 |
Mycobacterium tuberculosis | Conserved protein | 0.0106 | 0.0111 | 0.0146 |
Echinococcus multilocularis | zinc finger protein | 0.0029 | 0.001 | 0.0009 |
Mycobacterium tuberculosis | Conserved protein | 0.0106 | 0.0111 | 0.0146 |
Schistosoma mansoni | Smad4 | 0.0041 | 0.0026 | 0.0035 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.0161 | 0.0156 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0038 | 0.0022 | 0.0002 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0037 | 0.0021 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0111 | 0.0153 |
Leishmania major | folylpolyglutamate synthetase | 0.042 | 0.0517 | 0.0512 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0362 | 0.0441 | 0.0608 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0054 | 0.0075 |
Wolbachia endosymbiont of Brugia malayi | folate-dependent phosphoribosylglycinamide formyltransferase PurN | 0.0051 | 0.0039 | 0.019 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0307 | 0.0371 | 0.0501 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0111 | 0.0153 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0362 | 0.0441 | 0.0599 |
Plasmodium falciparum | bifunctional dihydrofolate reductase-thymidylate synthase | 0.7738 | 1 | 1 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0043 | 0.0028 | 0.003 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0106 | 0.0111 | 0.0153 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0037 | 0.0021 | 0.0026 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0328 | 0.0397 | 0.0547 |
Echinococcus granulosus | snurportin 1 | 0.0617 | 0.0773 | 0.1067 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0307 | 0.037 | 0.035 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0028 | 0.0009 | 0.0008 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0328 | 0.0397 | 0.0468 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0145 | 0.0161 | 0.022 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0046 | 0.0033 | 0.0028 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0037 | 0.0021 | 0.032 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0685 | 0.086 | 0.2469 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 14.1 % | Ability to displace [3H]- WIN 35,428 from Dopamine Transporter of rat striatal membrane at a concentration of 10 E-6 M | ChEMBL. | 12213053 |
Ratio (functional) | < 0.002 | Ratio of the IC50 value of Mazindol to that of the compound. | ChEMBL. | 12213053 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.