Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor II (thrombin) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0415 | 0.4432 | 0.8394 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0482 | 0.528 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0821 | 0.96 | 0.96 |
Loa Loa (eye worm) | hypothetical protein | 0.0818 | 0.9552 | 0.995 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0415 | 0.4432 | 0.8394 |
Onchocerca volvulus | 0.0067 | 0 | 0.5 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0482 | 0.528 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0482 | 0.528 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0821 | 0.96 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0821 | 0.96 | 0.96 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0067 | 0 | 0.5 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0067 | 0 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0415 | 0.4432 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0067 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.