TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 230.262 | Formula: C13H14N2O2
H donors: 1 H acceptors: 1 LogP: 2.18 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: COc1cccc2c1c(N)c1c(n2)OCCC1
InChi: 1S/C13H14N2O2/c1-16-10-6-2-5-9-11(10)12(14)8-4-3-7-17-13(8)15-9/h2,5-6H,3-4,7H2,1H3,(H2,14,15)
InChiKey: ZWEQTMLHBVSDBQ-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	acetylcholinesterase (Yt blood group)	Starlite/ChEMBL	No references

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Echinococcus granulosus	carboxylesterase 5A	Get druggable targets OG5_126875	All targets in OG5_126875
Brugia malayi	Carboxylesterase family protein	Get druggable targets OG5_126875	All targets in OG5_126875
Schistosoma japonicum	ko:K01049 acetylcholinesterase [EC3.1.1.7], putative	Get druggable targets OG5_126875	All targets in OG5_126875
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126875	All targets in OG5_126875
Echinococcus multilocularis	acetylcholinesterase	Get druggable targets OG5_126875	All targets in OG5_126875
Loa Loa (eye worm)	carboxylesterase	Get druggable targets OG5_126875	All targets in OG5_126875
Brugia malayi	Carboxylesterase family protein	Get druggable targets OG5_126875	All targets in OG5_126875
Echinococcus granulosus	acetylcholinesterase	Get druggable targets OG5_126875	All targets in OG5_126875
Echinococcus multilocularis	acetylcholinesterase	Get druggable targets OG5_126875	All targets in OG5_126875
Echinococcus multilocularis	carboxylesterase 5A	Get druggable targets OG5_126875	All targets in OG5_126875
Schistosoma japonicum	Acetylcholinesterase 1 precursor, putative	Get druggable targets OG5_126875	All targets in OG5_126875
Loa Loa (eye worm)	acetylcholinesterase 1	Get druggable targets OG5_126875	All targets in OG5_126875
Loa Loa (eye worm)	hypothetical protein	Get druggable targets OG5_126875	All targets in OG5_126875
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	Get druggable targets OG5_126875	All targets in OG5_126875
Echinococcus granulosus	acetylcholinesterase	Get druggable targets OG5_126875	All targets in OG5_126875

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Brugia malayi	Carboxylesterase family protein	acetylcholinesterase (Yt blood group)	614 aa	510 aa	26.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Giardia lamblia	Purine nucleoside phosphorylase lateral transfer candidate	0.0519	0.7015	1
Loa Loa (eye worm)	hypothetical protein	0.0135	0.1647	0.2965
Trichomonas vaginalis	conserved hypothetical protein	0.0107	0.1263	0.167
Trypanosoma cruzi	PAB1-binding protein , putative	0.0026	0.0131	0.0908
Echinococcus multilocularis	acetylcholinesterase	0.0082	0.0906	0.0889
Trichomonas vaginalis	chromobox protein, putative	0.0038	0.0292	0.0263
Entamoeba histolytica	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.5
Loa Loa (eye worm)	hypothetical protein	0.0411	0.5513	1
Brugia malayi	latrophilin 2 splice variant baaae	0.0031	0.0191	0.0273
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0186	0.2368	0.3359
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0519	0.7015	0.7009
Onchocerca volvulus	Alhambra homolog	0.0057	0.0557	0.0596
Toxoplasma gondii	PHD-finger domain-containing protein	0.0057	0.0557	0.4329
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0519	0.7015	0.7009
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Brugia malayi	hypothetical protein	0.0214	0.2747	0.3916
Brugia malayi	AF-10 protein	0.0019	0.0021	0.003
Schistosoma mansoni	uridine phosphorylase	0.0107	0.1263	0.178
Echinococcus multilocularis	jumonji domain containing protein	0.0079	0.0869	0.0852
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0045	0.0391	0.0557
Loa Loa (eye worm)	jmjC domain-containing protein	0.0118	0.1405	0.2524
Brugia malayi	Heterochromatin protein 1	0.0063	0.0641	0.0914
Brugia malayi	Muscleblind-like protein	0.0135	0.1647	0.2348
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Loa Loa (eye worm)	hypothetical protein	0.0026	0.0131	0.0206
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0058	0.0576	0.0798
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0056	0.0546	0.0755
Entamoeba histolytica	hypothetical protein	0.0107	0.1263	0.5
Trypanosoma cruzi	nucleoside phosphorylase, putative	0.0107	0.1263	1
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0026
Giardia lamblia	5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase	0.0107	0.1263	0.1093
Brugia malayi	PHD-finger family protein	0.0019	0.0021	0.003
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Echinococcus multilocularis	acetylcholinesterase	0.0082	0.0906	0.0889
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0406	0.5443	0.9874
Schistosoma mansoni	hypothetical protein	0.0057	0.0557	0.077
Echinococcus multilocularis	lysine specific demethylase 5A	0.0069	0.0725	0.0708
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0254	0.0209
Brugia malayi	chromobox protein homolog 3	0.0035	0.0254	0.0363
Plasmodium falciparum	ataxin-2 like protein, putative	0.0026	0.0131	0.0908
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0519	0.7015	0.7009
Leishmania major	hypothetical protein, conserved	0.0026	0.0131	0.0908
Schistosoma mansoni	family S9 non-peptidase homologue (S09 family)	0.0082	0.0906	0.1269
Schistosoma mansoni	uridine phosphorylase	0.0107	0.1263	0.178
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0044	0.037	0.0528
Onchocerca volvulus		0.0462	0.6228	0.8855
Loa Loa (eye worm)	uridine phosphorylase	0.0107	0.1263	0.2266
Plasmodium vivax	SET domain protein, putative	0.0058	0.0576	0.4482
Loa Loa (eye worm)	hypothetical protein	0.0058	0.0576	0.1016
Schistosoma mansoni	purine nucleoside phosphorylase	0.0519	0.7015	1
Toxoplasma gondii	phosphorylase family protein	0.0107	0.1263	1
Trypanosoma brucei	PHD-zinc-finger like domain containing protein, putative	0.0019	0.0021	0.0026
Echinococcus granulosus	acetylcholinesterase	0.0082	0.0906	0.1269
Entamoeba histolytica	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.5
Toxoplasma gondii	Purine nucleoside phosphorylase	0.0107	0.1263	1
Brugia malayi	Bromodomain containing protein	0.0057	0.0557	0.0794
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0519	0.7015	0.7009
Entamoeba histolytica	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.5
Treponema pallidum	purine nucleoside phosphorylase (deoD)	0.0107	0.1263	0.5
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0026
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0045	0.0391	0.0678
Mycobacterium tuberculosis	Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP)	0.0519	0.7015	1
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0026
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0045	0.0391	0.0557
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Toxoplasma gondii	PHD-finger domain-containing protein	0.0019	0.0021	0.0026
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Loa Loa (eye worm)	hypothetical protein	0.0045	0.0391	0.0678
Trichomonas vaginalis	set domain proteins, putative	0.0462	0.6228	0.8861
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Echinococcus granulosus	lysine specific demethylase 5A	0.0069	0.0725	0.101
Brugia malayi	MH2 domain containing protein	0.0108	0.1269	0.1809
Trichomonas vaginalis	conserved hypothetical protein	0.0107	0.1263	0.167
Trichomonas vaginalis	chromobox protein, putative	0.0063	0.0641	0.0768
Echinococcus multilocularis	chromobox protein 1	0.0063	0.0641	0.0624
Loa Loa (eye worm)	MH2 domain-containing protein	0.0108	0.1269	0.2276
Schistosoma mansoni	purine nucleoside phosphorylase	0.0519	0.7015	1
Entamoeba histolytica	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.5
Loa Loa (eye worm)	hypothetical protein	0.0135	0.1647	0.2965
Loa Loa (eye worm)	S-methyl-5'-thioadenosine phosphorylase MTAP	0.0107	0.1263	0.2266
Loa Loa (eye worm)	hypothetical protein	0.0098	0.1126	0.2016
Onchocerca volvulus		0.0069	0.072	0.0834
Trichomonas vaginalis	chromobox protein, putative	0.0038	0.0292	0.0263
Loa Loa (eye worm)	jmjC domain-containing protein	0.0069	0.0725	0.1286
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0021	0.0006
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0191	0.0316
Echinococcus granulosus	carboxylesterase 5A	0.0082	0.0906	0.1269
Plasmodium falciparum	conserved Plasmodium membrane protein, unknown function	0.0019	0.0021	0.0026
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0058	0.0576	0.0559
Schistosoma mansoni	methylthioadenosine phosphorylase	0.0107	0.1263	0.178
Giardia lamblia	5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase	0.0107	0.1263	0.1093
Giardia lamblia	UPL-1	0.0107	0.1263	0.1093
Schistosoma mansoni	survival motor neuron protein	0.0044	0.037	0.0503
Loa Loa (eye worm)	hypothetical protein	0.0214	0.2747	0.4967
Trypanosoma cruzi	PAB1-binding protein , putative	0.0026	0.0131	0.0908
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0069	0.0725	0.101
Echinococcus multilocularis	peregrin	0.0057	0.0557	0.054
Trichomonas vaginalis	purine nucleoside phosphorylase I, putative	0.0519	0.7015	1
Schistosoma mansoni	hypothetical protein	0.0031	0.0191	0.0248
Mycobacterium leprae	Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP)	0.0519	0.7015	1
Echinococcus granulosus	methylthioadenosine phosphorylase	0.0107	0.1263	0.178
Echinococcus multilocularis	uridine phosphorylase 1	0.0107	0.1263	0.1247
Plasmodium vivax	hypothetical protein, conserved	0.0057	0.0557	0.4329
Brugia malayi	jmjC domain containing protein	0.0186	0.2368	0.3376
Brugia malayi	Pre-SET motif family protein	0.0058	0.0576	0.0821
Onchocerca volvulus	Purine nucleoside phosphorylase homolog	0.0519	0.7015	1
Schistosoma mansoni	chromobox protein	0.0063	0.0641	0.089
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Loa Loa (eye worm)	hypothetical protein	0.0028	0.0148	0.0236
Echinococcus granulosus	PHD finger protein rhinoceros	0.0057	0.0557	0.077
Echinococcus granulosus	uridine phosphorylase 1	0.0107	0.1263	0.178
Trypanosoma cruzi	nucleoside phosphorylase, putative	0.0107	0.1263	1
Onchocerca volvulus		0.0044	0.037	0.0324
Echinococcus multilocularis	chromobox protein 1	0.0063	0.0641	0.0624
Loa Loa (eye worm)	transcription factor SMAD2	0.0108	0.1269	0.2276
Plasmodium falciparum	ataxin-2 like protein, putative	0.0026	0.0131	0.0908
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0038	0.0292	0.021
Loa Loa (eye worm)	PHD-finger family protein	0.0057	0.0557	0.0981
Loa Loa (eye worm)	hypothetical protein	0.0082	0.0906	0.1616
Echinococcus granulosus	jumonji domain containing protein	0.0079	0.0869	0.1216
Entamoeba histolytica	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.5
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0411	0.5513	0.5504
Mycobacterium ulcerans	purine nucleoside phosphorylase	0.0519	0.7015	1
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Schistosoma mansoni	jumonji domain containing protein	0.0148	0.1832	0.2593
Trypanosoma cruzi	methylthioadenosine phosphorylase, putative	0.0107	0.1263	1
Loa Loa (eye worm)	acetylcholinesterase 1	0.0082	0.0906	0.1616
Brugia malayi	MTAP	0.0107	0.1263	0.1801
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0069	0.0725	0.101
Loa Loa (eye worm)	carboxylesterase	0.0082	0.0906	0.1616
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0557	0.0981
Trypanosoma cruzi	methylthioadenosine phosphorylase, putative	0.0107	0.1263	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0058	0.0576	0.0798
Echinococcus multilocularis	survival motor neuron protein 1	0.0214	0.2747	0.2734
Plasmodium falciparum	purine nucleoside phosphorylase	0.0107	0.1263	1
Schistosoma mansoni	hypothetical protein	0.0019	0.0021	0.0005
Brugia malayi	purine nucleoside phosphorylase I, inosine and guanosine-specific family protein	0.0519	0.7015	1
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0411	0.5513	0.5504
Trypanosoma brucei	uridine phosphorylase	0.0107	0.1263	1
Toxoplasma gondii	LsmAD domain-containing protein	0.0026	0.0131	0.0908
Brugia malayi	F/Y-rich N-terminus family protein	0.0021	0.0051	0.0073
Trypanosoma brucei	PAB1-binding protein , putative	0.0026	0.0131	0.0908
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0035	0.0254	0.0155
Brugia malayi	hypothetical protein	0.0026	0.0131	0.0187
Toxoplasma gondii	PHD-finger domain-containing protein	0.0057	0.0557	0.4329
Brugia malayi	uridine phosphorylase family protein	0.0107	0.1263	0.1801
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.0058	0.0576	0.4482
Echinococcus multilocularis	methylthioadenosine phosphorylase	0.0107	0.1263	0.1247
Brugia malayi	Pre-SET motif family protein	0.0406	0.5443	0.776
Brugia malayi	PHD-finger family protein	0.0057	0.0557	0.0794
Trichomonas vaginalis	chromobox protein, putative	0.0063	0.0641	0.0768
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0058	0.0576	0.0798
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Trypanosoma brucei	PHD-zinc-finger like domain containing protein, putative	0.0019	0.0021	0.0026
Trichomonas vaginalis	conserved hypothetical protein	0.0035	0.0254	0.0209
Echinococcus granulosus	acetylcholinesterase	0.0082	0.0906	0.1269
Echinococcus granulosus	histone lysine methyltransferase setb	0.0058	0.0576	0.0798
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0519	0.7015	0.7009
Echinococcus granulosus	survival motor neuron protein 1	0.0214	0.2747	0.39
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.0058	0.0576	0.0559
Brugia malayi	Carboxylesterase family protein	0.0082	0.0906	0.1291
Echinococcus multilocularis	muscleblind protein 1	0.0135	0.1647	0.1632
Trypanosoma brucei	methylthioadenosine phosphorylase, putative	0.0107	0.1263	1
Leishmania major	methylthioadenosine phosphorylase, putative	0.0107	0.1263	1
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.0069	0.072	0.1003
Schistosoma mansoni	methylthioadenosine phosphorylase	0.0107	0.1263	0.178
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0057	0.0557	0.054
Echinococcus granulosus	purine nucleoside phosphorylase	0.0519	0.7015	1
Plasmodium falciparum	phd finger protein, putative	0.0057	0.0557	0.4329
Echinococcus multilocularis	muscleblind protein	0.0135	0.1647	0.1632
Treponema pallidum	pfs protein (pfs)	0.0107	0.1263	0.5
Plasmodium vivax	ataxin-2 like protein, putative	0.0026	0.0131	0.0908
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0057	0.0557	0.077
Echinococcus granulosus	chromobox protein 1	0.0063	0.0641	0.089
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0021	0.0051	0.0047
Echinococcus granulosus	inosine guanosine and xanthosine phosphorylase	0.0411	0.5513	0.7853
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0254	0.043
Entamoeba histolytica	MTA/SAH nucleosidase, putative	0.0107	0.1263	0.5
Schistosoma mansoni	hypothetical protein	0.0044	0.037	0.0503
Echinococcus granulosus	muscleblind protein	0.0135	0.1647	0.2329
Echinococcus granulosus	chromobox protein 1	0.0063	0.0641	0.089
Echinococcus granulosus	peregrin	0.0057	0.0557	0.077
Schistosoma mansoni	chromobox protein	0.0063	0.0641	0.089
Plasmodium vivax	hypothetical protein, conserved	0.0019	0.0021	0.0026
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0186	0.2368	0.2354
Echinococcus multilocularis	carboxylesterase 5A	0.0082	0.0906	0.0889
Loa Loa (eye worm)	heterochromatin protein 1	0.0063	0.0641	0.1133
Brugia malayi	jmjC domain containing protein	0.0069	0.0725	0.1033
Treponema pallidum	uridine phosphorylase (udp)	0.0107	0.1263	0.5
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Plasmodium vivax	purine nucleoside phosphorylase, putative	0.0107	0.1263	1
Chlamydia trachomatis	AMP nucleosidase	0.0107	0.1263	0.5
Leishmania major	nucleoside phosphorylase-like protein	0.0107	0.1263	1
Toxoplasma gondii	phosphorylase family protein	0.0107	0.1263	1
Brugia malayi	jmjC domain containing protein	0.0018	0.0018	0.0026
Toxoplasma gondii	WD domain, G-beta repeat-containing protein	0.0019	0.0021	0.0026
Trichomonas vaginalis	purine nucleoside phosphorylase, putative	0.0107	0.1263	0.167
Echinococcus multilocularis	purine nucleoside phosphorylase	0.0519	0.7015	0.7009
Trypanosoma cruzi	nucleoside phosphorylase, putative	0.0107	0.1263	1
Schistosoma mansoni	methylthioadenosine phosphorylase	0.0107	0.1263	0.178
Loa Loa (eye worm)	hypothetical protein	0.0082	0.0906	0.1616
Brugia malayi	Carboxylesterase family protein	0.0082	0.0906	0.1291

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 606 nM	In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.	ChEMBL.	No reference
IC50 (binding)	= 606 nM	In vitro inhibition of acetylcholinesterase isolated from human erythrocytes.	ChEMBL.	No reference
pKa (ADMET)	= 8.11	Compound was evaluated for its acid dissociation constant	ChEMBL.	No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL134154

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 229743