Detailed information for compound 229911

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 356.335 | Formula: C13H20N6O6
  • H donors: 7 H acceptors: 8 LogP: -2.34 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCC(CNc1nc(N)c2c(n1)n(cn2)[C@@H]1O[C@H]([C@H]([C@@H]1O)O)CO)O
  • InChi: 1S/C13H20N6O6/c14-10-7-11(18-13(17-10)15-1-5(22)2-20)19(4-16-7)12-9(24)8(23)6(3-21)25-12/h4-6,8-9,12,20-24H,1-3H2,(H3,14,15,17,18)/t5?,6?,8-,9-,12?/m0/s1
  • InChiKey: ILATVSFGCGLASB-QTGQCUOBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0043 0.052 0.0741
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.045 0.2406
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.036 0.0457
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0169 0.247 0.2556
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0032 0.0345 0.0343
Onchocerca volvulus 0.0017 0.0108 0.0152
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0493 0.0509
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Schistosoma mansoni nuclear hormone receptor 0.0027 0.0265 0.0272
Echinococcus granulosus DNA methyltransferase 2, putative 0.0022 0.0192 0.0272
Loa Loa (eye worm) hypothetical protein 0.0023 0.0206 0.0292
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0015 0.0073 0.0108
Mycobacterium tuberculosis Conserved hypothetical protein 0.01 0.1397 0.2586
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Schistosoma mansoni blooms syndrome DNA helicase 0.0069 0.0913 0.0943
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.036 0.1925
Plasmodium vivax DNA repair protein REV1, putative 0.0031 0.0328 0.0409
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0121 0.017
Onchocerca volvulus 0.0015 0.0073 0.0102
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Echinococcus granulosus ecdysone induced protein 78C 0.0027 0.0265 0.0375
Echinococcus granulosus General substrate transporter 0.0089 0.123 0.1756
Plasmodium vivax hexose transporter 0.0104 0.1456 0.2111
Echinococcus multilocularis histone acetyltransferase MYST2 0.0118 0.1672 0.2388
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0014 0.0067 0.0094
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.041 0.0408
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.033 0.1878
Brugia malayi hypothetical protein 0.0013 0.0044 0.0063
Brugia malayi 6-phosphofructokinase 0.0123 0.1747 0.2498
Schistosoma mansoni coup transcription factor 0.0027 0.0265 0.0272
Brugia malayi nuclear receptor NHR-67 0.0013 0.0044 0.0063
Plasmodium vivax multidomain scavenger receptor, putative 0.0022 0.0191 0.0202
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.0912 0.0942
Loa Loa (eye worm) hypothetical protein 0.0022 0.0191 0.0271
Onchocerca volvulus 0.0015 0.0073 0.0102
Leishmania major hypothetical protein, conserved 0.0014 0.0064 0.0062
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0239 0.0339
Onchocerca volvulus 0.0015 0.0073 0.0102
Brugia malayi hypothetical protein 0.0014 0.0067 0.0096
Mycobacterium tuberculosis Conserved hypothetical protein 0.0345 0.5195 1
Trichomonas vaginalis dullard protein, putative 0.0014 0.0064 0.0331
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.015 0.0768
Plasmodium falciparum protein kinase 6 0.0441 0.6684 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0027 0.0265 0.0375
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.045 0.2406
Echinococcus multilocularis Carboxy terminal domain RNA polymerase II 0.0014 0.0064 0.0088
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.041 0.0408
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0253 0.0296
Loa Loa (eye worm) steroid hormone receptor 0.0027 0.0265 0.0376
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0903 0.1289
Plasmodium falciparum NLI interacting factor-like phosphatase, putative 0.0014 0.0064 0.001
Leishmania major hypothetical protein, conserved 0.0018 0.0121 0.0119
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0044 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Brugia malayi phosphofructokinase 0.0123 0.1747 0.2498
Schistosoma mansoni protein tyrosine phosphatase 0.0013 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0042 0.0493 0.0702
Plasmodium vivax vivapain-2 0.0019 0.0139 0.0124
Echinococcus granulosus nuclear receptor nhr 48 0.0013 0.0044 0.006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0067 0.0094
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Brugia malayi ImpB/MucB/SamB family protein 0.0155 0.2254 0.3222
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.002 0.0149 0.0211
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0265 0.0375
Echinococcus granulosus CTD small phosphatase protein like 0.0014 0.0064 0.0088
Onchocerca volvulus 0.0017 0.0108 0.0152
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) MBCTL1 0.0118 0.1672 0.2389
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0139 0.0142
Schistosoma mansoni serine/threonine protein kinase 0.0109 0.1529 0.1581
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0032 0.0345 0.0491
Loa Loa (eye worm) fibroinase 0.0019 0.0139 0.0196
Onchocerca volvulus 0.0015 0.0073 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0073 0.0382
Onchocerca volvulus 0.0019 0.0139 0.0196
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0328 0.0326
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0044 0.006
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0014 0.0057 0.0297
Echinococcus granulosus Carboxy terminal domain RNA polymerase II 0.0014 0.0064 0.0088
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.036 0.0782
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Plasmodium falciparum calcium-dependent protein kinase 3 0.0032 0.0345 0.0435
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0029 0.0039
Toxoplasma gondii protein kinase, putative 0.0294 0.44 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0019 0.0139 0.0196
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Leishmania major hypothetical protein, conserved 0.0015 0.0073 0.0071
Schistosoma mansoni sugar transporter 0.0015 0.0073 0.0074
Brugia malayi major facilitator superfamily protein 0.0015 0.0073 0.0104
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0032 0.0345 0.0435
Toxoplasma gondii cathepsin CPL 0.0019 0.0139 0.0278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0027 0.0265 0.0376
Plasmodium falciparum LCCL domain-containing protein 0.0022 0.0191 0.0202
Toxoplasma gondii sugar transporter ST2 0.0015 0.0073 0.0127
Giardia lamblia Hexose transporter 0.0015 0.0073 0.0465
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Entamoeba histolytica recQ family DNA helicase 0.0026 0.0252 0.1432
Brugia malayi jmjC domain containing protein 0.0018 0.0121 0.0173
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0346 0.0344
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Mycobacterium ulcerans hypothetical protein 0.0345 0.5195 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0152 0.0154
Echinococcus multilocularis eukaryotic translation initiation factor 4E 0.0039 0.045 0.064
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.036 0.1925
Brugia malayi hypothetical protein 0.0157 0.2285 0.3267
Echinococcus granulosus solute carrier family 22 0.0015 0.0073 0.0102
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0152 0.0154
Entamoeba histolytica cysteine proteinase, putative 0.0013 0.0043 0.0233
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0265 0.0378
Onchocerca volvulus 0.0015 0.0073 0.0102
Schistosoma mansoni 6-phosphofructokinase 0.0123 0.1747 0.1807
Echinococcus granulosus ephrin type A receptor 4 A 0.0073 0.0972 0.1387
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0328 0.0708
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.036 0.0782
Trypanosoma cruzi hexose transporter 0.0032 0.0346 0.0344
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0346 0.1849
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0112 0.1587 0.1585
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0493 0.0702
Trichomonas vaginalis DNA helicase recq, putative 0.0095 0.1318 0.7074
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0018 0.0121 0.0236
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0051 0.0642 0.0915
Trypanosoma brucei unspecified product 0.0069 0.0916 0.0914
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.015 1
Toxoplasma gondii transporter, major facilitator family protein 0.0015 0.0073 0.0127
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0912 0.091
Echinococcus multilocularis jumonji domain containing 1A 0.0018 0.0121 0.017
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0346 0.1849
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0073 0.0104
Mycobacterium ulcerans hypothetical protein 0.0031 0.0328 0.06
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.018 0.2631 0.3758
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.036 0.2052
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0118 0.1672 0.2388
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0206 0.0365
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0118 0.1672 0.2388
Brugia malayi jmjC domain containing protein 0.0018 0.0121 0.0173
Schistosoma mansoni terminal deoxycytidyl transferase 0.01 0.1397 0.1445
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0793 0.0791
Onchocerca volvulus 0.0015 0.0073 0.0102
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0962 0.096
Schistosoma mansoni jumonji domain containing protein 0.0066 0.0875 0.0904
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Brugia malayi Cam kinase protein 1 0.0032 0.0345 0.0493
Echinococcus granulosus RUN 0.0022 0.0191 0.0271
Entamoeba histolytica phosphofructokinase, putative 0.0123 0.1747 1
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0014 0.0057 0.0057
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0027 0.0265 0.0378
Brugia malayi Muscle positioning protein 4 0.0017 0.0108 0.0155
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0656 1 1
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0493 0.0702
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0013 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0346 0.0344
Loa Loa (eye worm) hypothetical protein 0.0014 0.0064 0.0088
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Brugia malayi Pip kinase protein 1 0.0014 0.0057 0.0082
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0123 0.1747 0.3268
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0057 0.0055
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.006 0.0773 0.1723
Echinococcus multilocularis dna polymerase kappa 0.013 0.1862 0.2659
Giardia lamblia Sugar-proton symporter 0.0015 0.0073 0.0465
Onchocerca volvulus Bile acid receptor homolog 0.0027 0.0265 0.0376
Trypanosoma brucei sugar transporter, putative 0.0015 0.0073 0.0071
Trypanosoma brucei DNA damage repair protein, putative 0.0031 0.0328 0.0326
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.015 0.0849
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0043 0.0218
Plasmodium falciparum JmjC domain-containing protein, putative 0.0018 0.0121 0.0096
Loa Loa (eye worm) hypothetical protein 0.0018 0.0128 0.018
Schistosoma mansoni cathepsin F (C01 family) 0.0013 0.0043 0.0042
Echinococcus multilocularis lysine specific demethylase 6a 0.0018 0.0121 0.017
Schistosoma mansoni ap endonuclease 0.002 0.015 0.0153
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) hypothetical protein 0.0017 0.0108 0.0152
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0121 0.017
Loa Loa (eye worm) hypothetical protein 0.0291 0.4347 0.6214
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0027 0.0265 0.0378
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0139 0.0787
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0123 0.1747 0.1745
Leishmania major DNA polymerase eta, putative 0.0086 0.1184 0.1183
Entamoeba histolytica phosphofructokinase, putative 0.0123 0.1747 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0585 0.0604
Brugia malayi Steroid receptor seven-up type 2 0.0027 0.0265 0.0378
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0962 0.096
Schistosoma mansoni protein kinase 0.0032 0.0345 0.0355
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0018 0.0121 0.0123
Schistosoma mansoni retinoic acid receptor RXR 0.0027 0.0265 0.0272
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0067 0.0096
Trypanosoma brucei DNA polymerase IV, putative 0.013 0.1862 0.1861
Loa Loa (eye worm) nuclear hormone receptor 0.0013 0.0044 0.006
Loa Loa (eye worm) sugar transporter 0.0015 0.0073 0.0102
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0044 0.006
Onchocerca volvulus 0.0027 0.0265 0.0376
Brugia malayi nuclear hormone receptor family member odr-7 0.0013 0.0044 0.0063
Mycobacterium ulcerans integral membrane transport protein 0.0015 0.0073 0.0108
Onchocerca volvulus 0.0013 0.0044 0.006
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0032 0.0345 0.0491
Brugia malayi hypothetical protein 0.0015 0.0073 0.0104
Echinococcus granulosus Polycystic kidney disease protein 0.0022 0.0191 0.0271
Entamoeba histolytica serine/threonine protein kinase, putative 0.0109 0.1529 0.875
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0032 0.0345 0.0435
Trypanosoma brucei glucose transporter 2A 0.0032 0.0346 0.0344
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Entamoeba histolytica phosphofructokinase, putative 0.0123 0.1747 1
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.036 0.1925
Trypanosoma cruzi DNA polymerase kappa, putative 0.013 0.1862 0.1861
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0123 0.1747 0.1745
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0039 0.045 0.0448
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0064 0.0331
Echinococcus granulosus polycomb protein SCMH1 0.0104 0.145 0.207
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0057 0.0055
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0206 0.034
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0168 0.2453 0.3616
Trypanosoma cruzi sugar transporter, putative 0.0015 0.0073 0.0071
Echinococcus multilocularis lysine specific demethylase 5A 0.0066 0.0875 0.1248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0014 0.0057 0.0079
Schistosoma mansoni hypothetical protein 0.018 0.2631 0.2723
Leishmania major cathepsin L-like protease 0.0019 0.0139 0.0137
Onchocerca volvulus 0.0015 0.0073 0.0102
Toxoplasma gondii sugar transporter ST3 0.0015 0.0073 0.0127
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0013 0.0044 0.006
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0316
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Schistosoma mansoni 6-phosphofructokinase 0.0123 0.1747 0.1807
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0014 0.0057 0.0055
Schistosoma mansoni protein kinase 0.0032 0.0345 0.0355
Brugia malayi nuclear receptor NHR-88 0.0027 0.0265 0.0378
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.1747 0.938
Trichomonas vaginalis ap endonuclease, putative 0.002 0.015 0.0796
Schistosoma mansoni glucose transport protein 0.0104 0.1456 0.1507
Loa Loa (eye worm) sugar transporter 0.0104 0.1456 0.208
Onchocerca volvulus 0.0017 0.0108 0.0152
Echinococcus multilocularis dnaJ subfamily B 0.0462 0.6997 1
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0346 0.1849
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0044 0.0043
Onchocerca volvulus 0.0072 0.096 0.137
Echinococcus multilocularis phd:f box containing protein 0.0018 0.0121 0.017
Echinococcus multilocularis MAM 0.0018 0.0128 0.018
Echinococcus multilocularis cpg binding protein 0.0072 0.0963 0.1374
Schistosoma mansoni rab6-interacting 0.0022 0.0191 0.0196
Trypanosoma brucei glucose transporter 1E 0.0032 0.0346 0.0344
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0782 0.078
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0044 0.006
Onchocerca volvulus 0.0019 0.0139 0.0196
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0109 0.1529 0.2184
Loa Loa (eye worm) hypothetical protein 0.0032 0.0345 0.0491
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0013 0.0044 0.006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Brugia malayi Cathepsin L-like cysteine proteinase 0.0013 0.0043 0.0061
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0055
Loa Loa (eye worm) hypothetical protein 0.0017 0.0108 0.0152
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0206 0.0292
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0014 0.0057 0.0079
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) CXXC zinc finger family protein 0.007 0.0934 0.1334
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.002 0.0149 0.0211
Giardia lamblia Sgs1 DNA helicase, putative 0.0051 0.0642 0.419
Brugia malayi ephrin receptor 1 precursor 0.0035 0.0383 0.0548
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0002 0.00000018201
Loa Loa (eye worm) hypothetical protein 0.0155 0.2254 0.322
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.015 0.097
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0206 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0265 0.0375
Schistosoma mansoni hypothetical protein 0.0022 0.0191 0.0196
Schistosoma mansoni kinase 0.0056 0.0717 0.074
Brugia malayi tailless protein 0.0013 0.0044 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0061 0.0793 0.0791
Loa Loa (eye worm) cysteine protease 0.0019 0.0139 0.0196
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0206 0.0292
Brugia malayi Nuclear hormone receptor-like 1 0.0027 0.0265 0.0378
Brugia malayi major facilitator superfamily protein 0.0015 0.0073 0.0104
Schistosoma mansoni hypothetical protein 0.0012 0.0029 0.0028
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0169 0.247 0.3528
Echinococcus multilocularis RUN 0.0022 0.0191 0.0271
Schistosoma mansoni hypothetical protein 0.0462 0.6997 0.7246
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0253 0.0251
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0585 0.0833
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0346 0.0344
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Echinococcus granulosus Sugar transporter ERD6 protein 0.0015 0.0073 0.0102
Onchocerca volvulus 0.0017 0.0108 0.0152
Schistosoma mansoni sugar transporter 0.0015 0.0073 0.0074
Echinococcus granulosus eukaryotic translation initiation factor 4E 0.0039 0.045 0.064
Schistosoma mansoni zinc finger protein 0.0013 0.0044 0.0043
Schistosoma mansoni glucose transport protein 0.0104 0.1456 0.1507
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.015 0.0212
Entamoeba histolytica cysteine proteinase, putative 0.0019 0.0139 0.0787
Onchocerca volvulus 0.0015 0.0073 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0027 0.0265 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0346 0.1849
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.018 0.2631 0.2723
Echinococcus multilocularis General substrate transporter 0.0089 0.123 0.1756
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0253 0.0296
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.041 0.0408
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0013 0.0044 0.0043
Echinococcus granulosus FTZ F1 alpha 0.0027 0.0265 0.0375
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0013 0.0044 0.006
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0014 0.0057 0.0055
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0014 0.0057 0.0079
Brugia malayi nuclear receptor RXR 0.0013 0.0044 0.0063
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0014 0.0067 0.0068
Entamoeba histolytica protein kinase, putative 0.0032 0.0345 0.1966
Brugia malayi orphan nuclear receptor NR2E1 0.0013 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0044 0.006
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0073 0.0102
Brugia malayi Carboxy-terminal domain RNA polymerase II polypeptide A smallphosphatase 1 0.0014 0.0064 0.0091
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0108 0.1513 0.1511
Trypanosoma brucei DNA polymerase IV, putative 0.0123 0.1747 0.1745
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Toxoplasma gondii hypothetical protein 0.0096 0.1326 0.2985
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0013 0.0044 0.006
Echinococcus multilocularis disco interacting protein 2 0.0043 0.052 0.0741
Schistosoma mansoni hypothetical protein 0.0014 0.0061 0.0061
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0027 0.0265 0.0375
Brugia malayi hypothetical protein 0.0461 0.6994 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.015 0.0257
Schistosoma mansoni hypothetical protein 0.0104 0.1456 0.1507
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.033 0.1761
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0493 0.0705
Brugia malayi cathepsin L-like precursor 0.0013 0.0043 0.0061
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Schistosoma mansoni lozenge 0.0058 0.0743 0.0768
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0168 0.2453 0.5558
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Brugia malayi nuclear hormone receptor 0.0013 0.0044 0.0063
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.013 0.1862 1
Trypanosoma cruzi cysteine peptidase, putative 0.0072 0.0962 0.096
Plasmodium falciparum mitogen-activated protein kinase 2 0.0168 0.2453 0.3616
Schistosoma mansoni sugar transporter 0.0015 0.0073 0.0074
Echinococcus multilocularis solute carrier family 22 0.0015 0.0073 0.0102
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.033 0.0468
Echinococcus granulosus cathepsin L cysteine proteinase 0.0019 0.0139 0.0196
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0585 0.0833
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0206 0.0365
Schistosoma mansoni protein phosphatase 2C 0.0018 0.0121 0.0123
Entamoeba histolytica recQ family helicase, putative 0.0025 0.0236 0.1344
Schistosoma mansoni rab6-interacting 0.0022 0.0191 0.0196
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0265 0.0378
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0058
Mycobacterium ulcerans 6-phosphofructokinase 0.0123 0.1747 0.3341
Echinococcus granulosus thyroid hormone receptor alpha 0.0013 0.0044 0.006
Onchocerca volvulus Serine\/threonine kinase homolog 0.0109 0.1529 0.2184
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Brugia malayi nuclear hormone receptor family member nhr-6 0.0013 0.0044 0.0063
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0014 0.0067 0.0094
Trypanosoma brucei Eukaryotic translation initiation factor 4E-1 0.0039 0.045 0.0448
Trypanosoma cruzi glucose transporter, putative 0.0015 0.0073 0.0071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Toxoplasma gondii eukaryotic initiation factor-4E, putative 0.0039 0.045 0.0986
Brugia malayi CXXC zinc finger family protein 0.007 0.0934 0.1336
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0912 0.091
Plasmodium vivax JmjC domain containing protein 0.0018 0.0121 0.0096
Trichomonas vaginalis sugar transport protein, putative 0.0015 0.0073 0.0382
Brugia malayi Disco-interacting protein 2 homolog 0.0043 0.052 0.0744
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0014 0.0057 0.0091
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0032 0.0345 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0027 0.0265 0.0378
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.1031 0.103
Trichomonas vaginalis DNA helicase recq1, putative 0.0095 0.1318 0.7074
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0067 0.0094
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0014 0.0067 0.0068
Brugia malayi Protein-tyrosine phosphatase 1 0.001 0.0002 0.0003
Schistosoma mansoni lipoxygenase 0.0133 0.1908 0.1975
Leishmania major cathepsin L-like protease 0.0072 0.0962 0.096
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0015 0.0073 0.0102
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0206 0.043
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0015 0.0073 0.0074
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.033 0.2146
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.036 0.0457
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0064 0.001
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0903 0.0934
Loa Loa (eye worm) hypothetical protein 0.0018 0.0128 0.018
Schistosoma mansoni blooms syndrome DNA helicase 0.0026 0.0252 0.0259
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.036 0.1925
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) pip kinase 1 0.0014 0.0057 0.0079
Onchocerca volvulus 0.0022 0.0191 0.0271
Echinococcus multilocularis 6 phosphofructokinase 0.0123 0.1747 0.2494
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.033 0.1115
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Onchocerca volvulus 0.0019 0.0139 0.0196
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0058
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0044 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0027 0.0265 0.0378
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0027 0.0265 0.0375
Schistosoma mansoni protein kinase 0.0032 0.0345 0.0355
Trypanosoma brucei DNA damage repair protein, putative 0.0031 0.0328 0.0326
Onchocerca volvulus 0.0013 0.0044 0.006
Brugia malayi Doublecortin family protein 0.0022 0.0191 0.0274
Loa Loa (eye worm) hypothetical protein 0.0031 0.033 0.0469
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0092 0.1274 0.1273
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0027 0.0265 0.0376
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0027 0.0265 0.0272
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0051 0.0642 0.0915
Plasmodium vivax vivapain-2 0.0019 0.0139 0.0124
Schistosoma mansoni jumonji domain containing protein 0.0018 0.0121 0.0123
Loa Loa (eye worm) FYVE zinc finger family protein 0.0014 0.0057 0.0079
Giardia lamblia Nuclear LIM interactor-interacting factor 1 0.0014 0.0064 0.0403
Echinococcus granulosus lysine specific demethylase 5A 0.0068 0.0903 0.1289
Leishmania major myo-inositol/proton symporter (MIT) 0.0015 0.0073 0.0071
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0328 0.0326
Echinococcus multilocularis polycomb protein SCMH1 0.0104 0.145 0.207
Loa Loa (eye worm) hypothetical protein 0.0018 0.0128 0.018
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0044 0.0063
Brugia malayi Protein-tyrosine phosphatase 0.0013 0.0044 0.0063
Echinococcus granulosus bloom syndrome protein 0.0095 0.1318 0.1881
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0014 0.0067 0.0094
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0064 0.0062
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Echinococcus multilocularis cysteine protease 0.0019 0.0139 0.0196
Loa Loa (eye worm) DR-78 0.0013 0.0044 0.006
Loa Loa (eye worm) RecQ helicase 0.0095 0.1318 0.1882
Loa Loa (eye worm) mbt repeat family protein 0.0104 0.145 0.2071
Entamoeba histolytica deoxycytidyl transferase, putative 0.01 0.1397 0.7996
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0013 0.0043 0.0218
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0585 0.0834
Brugia malayi serine/threonine-protein kinase plk-2 0.0109 0.1529 0.2186
Brugia malayi Pip kinase protein 2 0.0169 0.247 0.3531
Leishmania major eukaryotic translation initiation factor eIF-4E, putative 0.0039 0.045 0.0448
Mycobacterium ulcerans DNA polymerase IV 0.013 0.1862 0.3563
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.045 0.2406
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.145 0.15
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0013 0.0044 0.006
Onchocerca volvulus 0.0017 0.0108 0.0152
Echinococcus multilocularis solute carrier family 22 0.0015 0.0073 0.0102
Onchocerca volvulus Putative transporter 0.0015 0.0073 0.0102
Echinococcus granulosus histone acetyltransferase MYST2 0.0118 0.1672 0.2388
Echinococcus granulosus 6 phosphofructokinase 0.0123 0.1747 0.2494
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0493 0.3217
Loa Loa (eye worm) hypothetical protein 0.0018 0.0121 0.017
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0642 0.1424
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0013 0.0044 0.006
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0493 0.0491
Giardia lamblia DINP protein human, muc B family 0.0108 0.1513 0.9894
Echinococcus granulosus solute carrier family 22 0.0015 0.0073 0.0102
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0086 0.1184 0.2662
Onchocerca volvulus 0.0015 0.0073 0.0102
Echinococcus multilocularis Polycystic kidney disease protein 0.0022 0.0191 0.0271
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.018 0.2631 0.2723
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0014 0.0057 0.0055
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0002 0.00000018201
Schistosoma mansoni RAR-like nuclear receptor 0.0027 0.0265 0.0272
Brugia malayi Cathepsin L-like precursor 0.0019 0.0139 0.0199
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trichomonas vaginalis CAMK family protein kinase 0.0032 0.0345 0.1844
Loa Loa (eye worm) pip kinase 2 0.0169 0.247 0.3529
Toxoplasma gondii hypothetical protein 0.0106 0.1484 0.3347
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0069 0.0912 0.1301
Brugia malayi Cathepsin L-like precursor 0.0019 0.0139 0.0199
Plasmodium falciparum calcium-dependent protein kinase 1 0.0032 0.0345 0.0435
Brugia malayi Cathepsin L-like precursor 0.0019 0.0139 0.0199
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0328 0.0326
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.01 0.1397 0.1445
Brugia malayi mbt repeat family protein 0.0104 0.145 0.2074
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0027 0.0265 0.0272
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0064 0.0331
Brugia malayi Cathepsin L-like precursor 0.0019 0.0139 0.0199
Schistosoma mansoni nuclear receptor 0.0013 0.0044 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Brugia malayi jmjC domain containing protein 0.0018 0.0121 0.0173
Trypanosoma brucei DNA polymerase eta, putative 0.0155 0.2254 0.2252
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Schistosoma mansoni hypothetical protein 0.0633 0.9656 1
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.036 0.1925
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0027 0.0265 0.0376
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0044 0.0043
Trichomonas vaginalis dullard protein, putative 0.0014 0.0064 0.0331
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0015 0.0073 0.0108
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0139 0.0739
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0032 0.0345 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0265 0.0378
Brugia malayi hypothetical protein 0.0013 0.0044 0.0063
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0022 0.0192 0.019
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0039 0.045 0.2565
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0027 0.0265 0.0376
Trichomonas vaginalis DNA helicase recq, putative 0.006 0.0782 0.4191
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0064 0.0064
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0014 0.0057 0.0055
Leishmania major glucose transporter, lmgt2 0.0032 0.0346 0.0344
Onchocerca volvulus 0.0015 0.0073 0.0102
Echinococcus multilocularis ecdysone induced protein 78C 0.0027 0.0265 0.0375
Mycobacterium ulcerans sugar transporter 0.0015 0.0073 0.0108
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0069 0.0912 0.1304
Echinococcus granulosus solute carrier family 22 0.0015 0.0073 0.0102
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.036 0.1925
Schistosoma mansoni loxhd1 0.0022 0.0191 0.0196
Schistosoma mansoni hypothetical protein 0.0018 0.0128 0.0131
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0096 0.1326 0.1914
Echinococcus granulosus Nuclear hormone receptor HR96 0.0013 0.0044 0.006
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0055
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0265 0.0272
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0252 0.0535
Echinococcus granulosus dna polymerase eta 0.0155 0.2254 0.3219
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Schistosoma mansoni nuclear lim interactor-interacting factor (nli-interacting factor) (nli-if) 0.0014 0.0064 0.0064
Schistosoma mansoni steroid hormone receptor ad4bp 0.0027 0.0265 0.0272
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Brugia malayi hypothetical protein 0.0026 0.0253 0.0362
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0109 0.1529 0.1527
Leishmania major eukaryotic translation initiation factor-like 0.0039 0.045 0.0448
Entamoeba histolytica NLI interacting factor-like phosphatase domain-containing protein 0.0014 0.0064 0.0353
Loa Loa (eye worm) hypothetical protein 0.0018 0.0121 0.017
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0013 0.0044 0.006
Brugia malayi SEA domain containing protein 0.0017 0.0108 0.0155
Echinococcus multilocularis calcium dependent protein kinase 0.003 0.0309 0.0439
Schistosoma mansoni cpg binding protein 0.0072 0.0963 0.0995
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0169 0.247 0.3528
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Brugia malayi Cathepsin L-like precursor 0.0019 0.0139 0.0199
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0206 0.0204
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0014 0.0057 0.0091
Echinococcus multilocularis FTZ F1 alpha 0.0027 0.0265 0.0375
Brugia malayi jmjC domain containing protein 0.0018 0.0121 0.0173
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0585 0.0833
Brugia malayi Nuclear hormone receptor-like 1 0.0014 0.0067 0.0096
Brugia malayi translation initiation factor 4E 0.0039 0.045 0.0643
Trypanosoma cruzi DNA polymerase kappa, putative 0.013 0.1862 0.1861
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0027 0.0265 0.0376
Leishmania major cathepsin L-like protease 0.0019 0.0139 0.0137
Echinococcus granulosus synaptic vesicle 2 protein 0.0015 0.0073 0.0102
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0027 0.0265 0.0272
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Loa Loa (eye worm) phosphofructokinase 0.0123 0.1747 0.2495
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0045 0.0061
Echinococcus multilocularis solute carrier family 22 0.0015 0.0073 0.0102
Loa Loa (eye worm) hypothetical protein 0.0013 0.0043 0.0058
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0032 0.0345 0.0748
Loa Loa (eye worm) hypothetical protein 0.0169 0.247 0.3529
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.015 0.0212
Brugia malayi ecdysone receptor 0.0013 0.0044 0.0063
Onchocerca volvulus 0.0019 0.0139 0.0196
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0104 0.1456 0.2079
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0014 0.0057 0.0079
Onchocerca volvulus 0.0019 0.0139 0.0196
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0014 0.0057 0.0055
Trypanosoma brucei hypothetical protein, conserved 0.0031 0.0328 0.0326
Brugia malayi Sugar transporter family protein 0.0104 0.1456 0.2082
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.031 0.4652 0.4651
Schistosoma mansoni ephrin receptor 0.0073 0.0972 0.1005
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0346 0.1849
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0252 0.025
Toxoplasma gondii histone lysine methyltransferase SET1 0.0061 0.0798 0.178
Loa Loa (eye worm) translation initiation factor 4E 0.0039 0.045 0.064
Trypanosoma cruzi hexose transporter, putative 0.0018 0.012 0.0118
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.0043 0.052 0.0537
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.015 0.0215
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0032 0.0345 0.0748
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0162 0.0859
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0069 0.0912 0.1301
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0069 0.0912 0.091
Schistosoma mansoni glucose transporter 0.0015 0.0073 0.0074
Brugia malayi ImpB/MucB/SamB family protein 0.01 0.1397 0.1998
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0027 0.0265 0.0375
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Schistosoma mansoni DNA helicase recq5 0.0051 0.0642 0.0663
Echinococcus multilocularis synaptic vesicle 2 protein 0.0015 0.0073 0.0102
Plasmodium falciparum calcium-dependent protein kinase 2 0.0032 0.0345 0.0435
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0695 0.3725
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0121 0.0119
Brugia malayi 6-phosphofructokinase 0.0123 0.1747 0.2498
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0191 0.0271
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0025 0.0236 0.0271
Loa Loa (eye worm) 6-phosphofructokinase 0.0123 0.1747 0.2495
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Chlamydia trachomatis lysine--tRNA ligase 0.0023 0.0206 0.5506
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Leishmania major cathepsin L-like protease 0.0072 0.0962 0.096
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0014 0.0057 0.0055
Brugia malayi Cathepsin L-like precursor 0.0019 0.0139 0.0199
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0013 0.0044 0.006
Loa Loa (eye worm) hypothetical protein 0.0051 0.0642 0.0915
Schistosoma mansoni lipoxygenase 0.0093 0.1288 0.1332
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0642 0.0918
Trichomonas vaginalis ap endonuclease, putative 0.002 0.015 0.0796
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.1031 0.103
Schistosoma mansoni serine/threonine protein kinase 0.0032 0.0345 0.0355
Echinococcus multilocularis JmjC domain containing protein 4 0.0018 0.0121 0.017
Onchocerca volvulus Protein ultraspiracle homolog 0.0027 0.0265 0.0376
Loa Loa (eye worm) hypothetical protein 0.0461 0.6994 1
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) hypothetical protein 0.0026 0.0252 0.0357
Loa Loa (eye worm) hypothetical protein 0.0018 0.0121 0.017
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0015 0.0073 0.0071
Onchocerca volvulus 0.0015 0.0073 0.0102
Plasmodium vivax NLI interacting factor-like phosphatase, putative 0.0014 0.0064 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0346 0.0344
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0585 0.0604
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.1529 0.1527
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0064 0.0331
Brugia malayi hypothetical protein 0.0015 0.0073 0.0104
Trypanosoma cruzi DNA polymerase eta, putative 0.0086 0.1184 0.1183
Echinococcus granulosus cpg binding protein 0.0072 0.0963 0.1374
Brugia malayi hypothetical protein 0.001 0.0002 0.0003
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0032 0.0345 0.0748
Echinococcus granulosus disco interacting protein 2 0.0043 0.052 0.0741
Echinococcus granulosus lysine specific demethylase 6a 0.0018 0.0121 0.017
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0253 0.0251
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0139 0.0196
Loa Loa (eye worm) hypothetical protein 0.0037 0.0413 0.0588
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Loa Loa (eye worm) hypothetical protein 0.0014 0.0067 0.0094
Brugia malayi nuclear receptor RXR 0.0014 0.0067 0.0096
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.036 0.0457
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0013 0.0044 0.006
Mycobacterium ulcerans DNA polymerase IV 0.013 0.1862 0.3563
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0206 0.0204
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0656 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0027 0.0265 0.0376
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0022 0.0192 0.0203
Echinococcus multilocularis cysteine protease 0.0019 0.0139 0.0196
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0656 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0076 0.1031 0.103
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0069 0.0912 0.0942
Leishmania major hypothetical protein, conserved 0.0026 0.0253 0.0251
Plasmodium vivax calcium-dependent protein kinase, putative 0.0032 0.0345 0.0435
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0206 0.0225
Echinococcus granulosus phd:f box containing protein 0.0018 0.0121 0.017
Brugia malayi Cathepsin L-like precursor 0.0013 0.0043 0.0061
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0493 0.0702
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0014 0.0057 0.0057
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0069 0.0912 0.1301
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0493 0.0491
Loa Loa (eye worm) ctsf protein 0.0019 0.0139 0.0196
Leishmania major DNA polymerase kappa, putative 0.0108 0.1513 0.1511
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0019 0.0139 0.0196
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0051 0.0642 0.0915
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0014 0.0057 0.0057
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0039 0.0443 0.0971
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.015 0.0148
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0118 0.1672 0.2391
Trypanosoma cruzi polo-like protein kinase, putative 0.0109 0.1529 0.1527
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0585 0.0836
Schistosoma mansoni ap endonuclease 0.002 0.015 0.0153
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0109 0.1529 0.2183
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0019 0.0139 0.0124
Trypanosoma cruzi DNA polymerase kappa, putative 0.013 0.1862 0.1861
Leishmania major protein kinase, putative 0.0032 0.0345 0.0343
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Loa Loa (eye worm) hypothetical protein 0.0014 0.0067 0.0094
Brugia malayi nuclear receptor NHR-88 0.0013 0.0044 0.0063
Leishmania major cysteine peptidase A (CPA) 0.0019 0.0139 0.0137
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0027 0.0265 0.0375
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0044 0.006
Schistosoma mansoni nuclear receptor 0.0013 0.0044 0.0043
Giardia lamblia DNA damage repair protein 0.0031 0.0328 0.2135
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.018 0.2631 0.3758
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.01 0.1397 0.1995
Schistosoma mansoni apoptosis regulator bax 0.018 0.2631 0.2723
Brugia malayi nuclear hormone receptor 0.0027 0.0265 0.0378
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0027 0.0265 0.0378
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0027 0.0265 0.0378
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0104 0.145 0.2071
Brugia malayi steroid hormone receptor 0.0027 0.0265 0.0378
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0014 0.0057 0.0057
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0051 0.0642 0.0915
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.01 0.1397 0.1995
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0019 0.0139 0.0739
Trypanosoma brucei DNA polymerase IV, putative 0.013 0.1862 0.1861
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Leishmania major cathepsin L-like protease 0.0072 0.0962 0.096
Toxoplasma gondii DNA methyltransferase 2, putative 0.0022 0.0192 0.0398
Trichomonas vaginalis conserved hypothetical protein 0.0104 0.1456 0.7819
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.1747 0.938
Trypanosoma brucei Mitochondrial import inner membrane translocase subunit TIM50 0.0014 0.0064 0.0062
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0346 0.1849
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0412 0.6227 0.8899
Onchocerca volvulus 0.0019 0.0139 0.0196
Echinococcus multilocularis bloom syndrome protein 0.0095 0.1318 0.1881
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0092 0.1274 0.1273
Brugia malayi hypothetical protein 0.0015 0.0073 0.0104
Echinococcus granulosus dnaJ subfamily B 0.0462 0.6997 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.013 0.1862 0.1861
Leishmania major DNA polymerase eta, putative 0.0155 0.2254 0.2252
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0027 0.0265 0.0378
Brugia malayi Protein-tyrosine phosphatase 0.001 0.0002 0.0003
Echinococcus granulosus dna polymerase kappa 0.013 0.1862 0.2659
Echinococcus granulosus SAM and MBT domain containing protein 0.0104 0.145 0.207
Onchocerca volvulus 0.0019 0.0139 0.0196
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0014 0.0057 0.0055
Onchocerca volvulus 0.0461 0.6994 1
Leishmania major DNA polymerase kappa, putative 0.0031 0.0328 0.0326
Brugia malayi Sugar transporter family protein 0.0015 0.0073 0.0104
Echinococcus granulosus solute carrier family 22 0.0015 0.0073 0.0102
Schistosoma mansoni glucose transport protein 0.0104 0.1456 0.1507
Trichomonas vaginalis nuclear lim interactor-interacting factor, putative 0.0014 0.0064 0.0331
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0191 0.0271
Loa Loa (eye worm) major facilitator superfamily transporter 0.0015 0.0073 0.0102
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0051 0.0642 0.0882
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0493 0.264
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0027 0.0265 0.0272
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Brugia malayi Papain family cysteine protease containing protein 0.0019 0.0139 0.0199
Plasmodium falciparum calcium-dependent protein kinase 4 0.0032 0.0345 0.0435
Trichomonas vaginalis DNA polymerase eta, putative 0.013 0.1862 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0027 0.0265 0.0375
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0066 0.0875 0.1248
Entamoeba histolytica hypothetical protein 0.0023 0.0206 0.1169
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0493 0.0702
Echinococcus granulosus cathepsin l1 0.0013 0.0043 0.0058
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.036 0.0782
Echinococcus multilocularis lipoxygenase domain containing protein 0.0022 0.0191 0.0271
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0493 0.2815
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0014 0.0067 0.0094
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Onchocerca volvulus 0.0018 0.0128 0.018
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0123 0.1747 1
Onchocerca volvulus 0.0043 0.052 0.0741
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0022 0.0192 0.0272
Onchocerca volvulus 0.007 0.0934 0.1334
Schistosoma mansoni hypothetical protein 0.0018 0.0128 0.0131
Leishmania major ATP-dependent phosphofructokinase 0.0123 0.1747 0.1745
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0066 0.0875 0.1248
Onchocerca volvulus 0.0015 0.0073 0.0102
Brugia malayi hypothetical protein 0.001 0.0002 0.0003
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0061 0.0788 0.1103
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Onchocerca volvulus 0.0169 0.247 0.3529
Brugia malayi Sugar transporter family protein 0.0015 0.0073 0.0104
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0346 0.0344
Toxoplasma gondii sugar transporter ST1 0.0015 0.0073 0.0127
Brugia malayi hypothetical protein 0.0022 0.0191 0.0274
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0027 0.0265 0.0376
Brugia malayi Bloom's syndrome protein homolog 0.0095 0.1318 0.1884
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0027 0.0265 0.0376
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.015 0.0148
Trichomonas vaginalis myo-inositol transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Treponema pallidum ATP-dependent DNA helicase 0.0026 0.0252 0.1357
Giardia lamblia Hypothetical protein 0.0014 0.0057 0.0362
Brugia malayi hypothetical protein 0.001 0.0002 0.0003
Trypanosoma brucei polo-like protein kinase 0.0109 0.1529 0.1527
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0014 0.0057 0.0082
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.033 0.0339
Schistosoma mansoni eukaryotic translation initiation factor 4e 0.0039 0.045 0.0464
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) runx1 0.0058 0.0743 0.106
Trichomonas vaginalis dullard protein, putative 0.0014 0.0064 0.0331
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.036 0.1925
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.033 0.0339
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0412 0.6227 0.8899
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0108 0.1513 0.1511
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.015 0.014
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.015 0.0151
Echinococcus multilocularis ephrin type A receptor 4 A 0.0073 0.0972 0.1387
Onchocerca volvulus 0.0157 0.2285 0.3265
Schistosoma mansoni DNA helicase recq1 0.0051 0.0642 0.0663
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0782 0.078
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.015 0.014
Onchocerca volvulus 0.0021 0.017 0.024
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0044 0.006
Plasmodium vivax sugar transporter, putative 0.0015 0.0073 0.0024
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0109 0.1529 0.2183
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0073 0.0382
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0157 0.2285 0.3265
Onchocerca volvulus 0.0015 0.0073 0.0102
Loa Loa (eye worm) hypothetical protein 0.0118 0.1672 0.2389
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0027 0.0265 0.0375
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0493 0.0702
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) TK/ALK protein kinase 0.0019 0.014 0.0198
Schistosoma mansoni polycystin 1-related 0.0022 0.0191 0.0196
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Schistosoma mansoni nuclear hormone receptor 0.0013 0.0044 0.0043
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0206 0.1097
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0206 0.1336
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0108 0.1513 0.2811
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0022 0.0192 0.1089
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0493 0.0702
Schistosoma mansoni cpg binding protein 0.007 0.0934 0.0966
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.036 1
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.041 0.0408
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Plasmodium falciparum cysteine proteinase falcipain 3 0.0019 0.0139 0.0124
Trypanosoma cruzi Eukaryotic translation initiation factor 4E-1 0.0039 0.045 0.0448
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) hypothetical protein 0.0014 0.0061 0.0084
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0493 0.0491
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.1747 0.938
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0013 0.0044 0.006
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0019 0.0139 0.0196
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0139 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0585 0.0604
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0018 0.0121 0.0236
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0695 0.3725
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0206 0.0211
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0026 0.0252 0.025
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0133 0.1908 0.2725
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0362
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Loa Loa (eye worm) histone methyltransferase 0.001 0.0002 0.00000018209
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0029 0.0039
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0086 0.1178 0.1691
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0027 0.0265 0.0272
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.015 0.0148
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0092 0.1274 0.1273
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0092 0.1274 0.1273
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0014 0.0057 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0073 0.0382
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0022 0.0192 0.0197
Brugia malayi Dual specificity protein phosphatase CDC14B 0.001 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.018 0.2631 0.3759
Trypanosoma brucei chrX additional, unordered contigs 0.0031 0.0328 0.0326
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0104 0.1456 0.2079
Loa Loa (eye worm) hypothetical protein 0.0061 0.0793 0.1131
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.041 0.0408
Schistosoma mansoni DNA polymerase eta 0.0155 0.2254 0.2332
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0253 0.0538
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0013 0.0044 0.0063
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0013 0.0044 0.006
Loa Loa (eye worm) 6-phosphofructokinase 0.0123 0.1747 0.2495
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Brugia malayi ecdysteroid receptor 0.0027 0.0265 0.0378
Schistosoma mansoni sugar transporter 0.0015 0.0073 0.0074
Entamoeba histolytica phosphoinositide kinase, putative 0.0014 0.0057 0.0316
Entamoeba histolytica protein kinase, putative 0.0032 0.0345 0.1966
Echinococcus multilocularis dna polymerase eta 0.0155 0.2254 0.3219
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Onchocerca volvulus 0.0015 0.0073 0.0102
Entamoeba histolytica cysteine protease, putative 0.0019 0.0139 0.0787
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Brugia malayi jmjC domain containing protein 0.0068 0.0903 0.1292
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.041 0.0532
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0022 0.0192 0.0398
Schistosoma mansoni hypothetical protein 0.0017 0.0108 0.011
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.036 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0253 0.036
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0073 0.0104
Toxoplasma gondii exonuclease III APE 0.002 0.015 0.0303
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0493 0.264
Echinococcus granulosus MAM 0.0018 0.0128 0.018
Trypanosoma cruzi hexose transporter, putative 0.0015 0.0073 0.0071
Brugia malayi mbt repeat family protein 0.0104 0.145 0.2074
Trichomonas vaginalis eukaryotic translation initiation factor 4E, putative 0.0039 0.045 0.2406
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0123 0.1747 1
Echinococcus granulosus transcription factor Dp 1 0.004 0.0463 0.0659
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0104 0.145 0.15
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0027 0.0265 0.0375
Brugia malayi hypothetical protein 0.0017 0.0109 0.0156
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.006 0.0782 0.078
Echinococcus multilocularis nuclear receptor nhr 48 0.0013 0.0044 0.006
Leishmania major cathepsin L-like protease 0.0019 0.0139 0.0137
Toxoplasma gondii Dullard family phosphatase domain-containing protein 0.0014 0.0064 0.0105
Brugia malayi Cathepsin L-like precursor 0.0013 0.0043 0.0061
Brugia malayi Nuclear hormone receptor E75 0.0013 0.0044 0.0063
Trichomonas vaginalis phosphofructokinase, putative 0.0123 0.1747 0.938
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.036 0.0457
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0069 0.0912 0.5215
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0013 0.0044 0.006
Loa Loa (eye worm) hypothetical protein 0.0072 0.096 0.137
Brugia malayi hypothetical protein 0.001 0.0002 0.0003
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0169 0.247 0.2556
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0493 0.264
Trypanosoma cruzi cysteine peptidase, putative 0.0019 0.0139 0.0137
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0051 0.0642 0.0915
Leishmania major DNA damage repair protein, putative 0.0031 0.0328 0.0326
Plasmodium vivax CDK-related protein kinase 6, putative 0.0441 0.6684 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0044 0.006
Leishmania major cathepsin L-like protease 0.0019 0.0139 0.0137
Entamoeba histolytica recQ family helicase, putative 0.006 0.0782 0.4468
Brugia malayi jmjC domain containing protein 0.0066 0.0875 0.1251
Schistosoma mansoni sex comb on midleg homolog 0.0104 0.145 0.15
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0072 0.0962 0.096
Plasmodium falciparum calcium-dependent protein kinase 5 0.0032 0.0345 0.0435
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0027 0.0265 0.0272
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.018 0.2631 0.3761
Echinococcus granulosus JmjC domain containing protein 4 0.0018 0.0121 0.017
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.001 0.0002 0.0003
Schistosoma mansoni nuclear receptor nhr-48 0.0013 0.0044 0.0043
Plasmodium falciparum hexose transporter 0.0104 0.1456 0.2111
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0253 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0073 0.0382
Echinococcus multilocularis 0.0014 0.0064 0.0088
Loa Loa (eye worm) hypothetical protein 0.0013 0.0044 0.006
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Loa Loa (eye worm) DOMON domain-containing protein 0.0017 0.0108 0.0152
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.031 0.4652 0.4651
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0013 0.0044 0.006
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0027 0.0265 0.0378
Trichomonas vaginalis glucose transporter, putative 0.0015 0.0073 0.0382
Trypanosoma cruzi DNA damage repair protein, putative 0.0031 0.0328 0.0326
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0015 0.0073 0.0024
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0642 0.0918
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Onchocerca volvulus Cathepsin F homolog 0.0019 0.0139 0.0196
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0253 0.0296
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Leishmania major glucose transporter, lmgt3 0.0032 0.0346 0.0344
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.031 0.4652 0.4651
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0014 0.0057 0.0297
Brugia malayi Protein kinase domain containing protein 0.0019 0.014 0.0201
Onchocerca volvulus 0.0022 0.0191 0.0271
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0018 0.0121 0.0119
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0073 0.0382
Plasmodium falciparum DNA repair protein REV1, putative 0.0031 0.0328 0.0409
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0585 0.0833
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0027 0.0265 0.0375
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0014 0.0057 0.0091
Schistosoma mansoni thyroid hormone receptor 0.0027 0.0265 0.0272
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0493 0.0491
Trypanosoma cruzi DNA damage repair protein, putative 0.0031 0.0328 0.0326
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.033 0.0471
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0032 0.0345 0.049
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.036 0.1982
Trypanosoma brucei DNA polymerase kappa, putative 0.013 0.1862 0.1861
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.01 0.1397 0.1995
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Onchocerca volvulus 0.0015 0.0073 0.0102
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trypanosoma cruzi major cysteine proteinase, putative 0.0057 0.0723 0.0721
Schistosoma mansoni phd/f-box containing protein 0.0018 0.0121 0.0123
Schistosoma mansoni hypothetical protein 0.018 0.2631 0.2723
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0055
Entamoeba histolytica eukaryotic translation initiation factor 4E, putative 0.0039 0.045 0.2565
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0014 0.0057 0.0079
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0206 0.0294
Leishmania major cathepsin L-like protease 0.0019 0.0139 0.0137
Trichomonas vaginalis CAMK family protein kinase 0.0109 0.1529 0.8208
Loa Loa (eye worm) apoptosis regulator protein 0.018 0.2631 0.3759
Giardia lamblia Kinase, PLK 0.0109 0.1529 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0069 0.0912 0.091
Schistosoma mansoni myelin transcription factor 1 myt1 0.0118 0.1672 0.173
Echinococcus multilocularis Protein lozenge 0.0058 0.0743 0.106
Brugia malayi polk-prov protein 0.0061 0.0793 0.1133
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0013 0.0044 0.0043
Brugia malayi hypothetical protein 0.0018 0.0128 0.0183
Echinococcus granulosus lipoxygenase domain containing protein 0.0022 0.0191 0.0271
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0014 0.0057 0.0055
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.033 0.0471
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0346 0.1849
Loa Loa (eye worm) nuclear receptor NHR-67 0.0013 0.0044 0.006
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0022 0.0192 0.0203
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0493 0.0509
Leishmania major glucose transporter, lmgt1 0.0032 0.0346 0.0344
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0044 0.006
Trypanosoma cruzi cruzipain precursor, putative 0.0072 0.0962 0.096
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0013 0.0044 0.006
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0014 0.0057 0.0055
Schistosoma mansoni phosphatidylserine receptor 0.0018 0.0121 0.0123
Loa Loa (eye worm) jmjC domain-containing protein 0.0018 0.0121 0.017
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0032 0.0345 0.049
Onchocerca volvulus 0.0015 0.0073 0.0102
Schistosoma mansoni cpg binding protein 0.0072 0.0963 0.0995
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0346 0.0344
Echinococcus multilocularis cathepsin L cysteine protease 0.0019 0.0139 0.0196
Loa Loa (eye worm) TK/EPH protein kinase 0.0092 0.1277 0.1824
Leishmania major modification methylase-like protein 0.0022 0.0192 0.019
Trypanosoma brucei unspecified product 0.0123 0.1747 0.1745
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0463 0.0659
Echinococcus granulosus jumonji domain containing 1A 0.0018 0.0121 0.017
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0903 0.0934
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0027 0.0265 0.0378
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.036 0.2345
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.018 0.2631 0.3758
Echinococcus granulosus calcium dependent protein kinase 0.003 0.0309 0.0439
Loa Loa (eye worm) hypothetical protein 0.0104 0.145 0.2071
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0066 0.0865 0.0863
Onchocerca volvulus 0.0104 0.145 0.2071
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0019 0.0139 0.0196
Loa Loa (eye worm) hypothetical protein 0.0031 0.033 0.0469
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0139 0.0196
Echinococcus multilocularis solute carrier family 22 0.0015 0.0073 0.0102
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.015 0.0212
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0044 0.0043
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.015 0.0148
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.018 0.2631 0.3758
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0346 0.0344
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0051 0.0642 0.1424
Loa Loa (eye worm) hypothetical protein 0.0019 0.0139 0.0196
Brugia malayi hypothetical protein 0.0014 0.0067 0.0096
Schistosoma mansoni DNA polymerase IV / kappa 0.0031 0.0328 0.0338
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) hypothetical protein 0.0022 0.0191 0.0271
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0027 0.0265 0.0375
Brugia malayi hypothetical protein 0.0022 0.0191 0.0274
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0133 0.1908 0.2725
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Brugia malayi Protein-tyrosine phosphatase containing protein 0.001 0.0002 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0019 0.0139 0.0739
Onchocerca volvulus 0.0013 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0461 0.6994 1
Trypanosoma brucei unspecified product 0.0069 0.0916 0.0914
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0018 0.0121 0.0119
Brugia malayi hypothetical protein 0.001 0.0002 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0155 0.2254 0.2252
Onchocerca volvulus Cathepsin L homolog 0.0019 0.0139 0.0196
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.041 0.0895
Trichomonas vaginalis sugar transporter, putative 0.0015 0.0073 0.0382
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0206 0.0211
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0019 0.0139 0.0739
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376
Plasmodium falciparum proline--tRNA ligase 0.0036 0.041 0.0532
Echinococcus granulosus cathepsin l1 0.0019 0.0139 0.0196
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0206 0.0204
Echinococcus multilocularis SAM and MBT domain containing protein 0.0104 0.145 0.207
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0027 0.0265 0.0375
Toxoplasma gondii facilitative glucose transporter GT1 0.0104 0.1456 0.3283
Loa Loa (eye worm) hypothetical protein 0.0015 0.0073 0.0102
Loa Loa (eye worm) doublecortin family protein 0.0022 0.0191 0.0271
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0019 0.0139 0.0124
Schistosoma mansoni cathepsin F (C01 family) 0.0019 0.0139 0.0142
Brugia malayi Major Facilitator Superfamily protein 0.0015 0.0073 0.0104
Leishmania major eukaryotic translation initiation factor-like protein 0.0039 0.045 0.0448
Brugia malayi conserved hypotetical protein 0.0013 0.0044 0.0063
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.033 0.0468
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0027 0.0265 0.0378
Brugia malayi photoreceptor-specific nuclear receptor 0.0027 0.0265 0.0378
Plasmodium falciparum protein kinase 7 0.0294 0.44 0.6553
Trypanosoma brucei glucose transporter, putative 0.0032 0.0346 0.0344
Loa Loa (eye worm) hypothetical protein 0.0027 0.0265 0.0376

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) NA 0 mM Inhibition of Trypanosoma brucei phosphoglycerate kinase (PGK); inactive at 4 mM ChEMBL. 11063610

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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