Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 4 ug ml-1 | In vitroantibacterial activity against methicillin-resistant S. a. 019 (Staphylococcus aureus ATCC 33591 ) | ChEMBL. | 14622995 |
MIC (functional) | = 4 ug ml-1 | In vitro antibacterial activity against vancomycin-resistant E. faecium 154 (Enterococcus faecium ATCC 12202) | ChEMBL. | 14622995 |
MIC (functional) | = 16 ug ml-1 | In vitro antibacterial activity against S. a. 213 (Staphylococcus. aureus ATCC 49951) | ChEMBL. | 14622995 |
MIC (functional) | = 16 ug ml-1 | In vitro antibacterial activity against S. a. 035 (S. aureus ATCC 29213) | ChEMBL. | 14622995 |
MIC (functional) | = 16 ug ml-1 | In vitro antibacterial activity against vancomycin-susceptible E. f. 034 (Enterococcus faecalis ATCC 29212) | ChEMBL. | 14622995 |
MIC (functional) | = 16 ug ml-1 | In vitro antibacterial activity against vancomycin-susceptible E. f. 153 (Enterococcus faecalis ATCC 29212) | ChEMBL. | 14622995 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.