Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0089 | 0.1043 | 1 |
Plasmodium vivax | protein prenyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.159 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0073 | 0.08 | 1 |
Echinococcus multilocularis | lysophospholipid acyltransferase 7 | 0.0023 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trichomonas vaginalis | type I geranylgeranyltransferase beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Trypanosoma cruzi | Protein prenyltransferase alpha subunit repeat, putative | 0.003 | 0.0136 | 0.1305 |
Loa Loa (eye worm) | animal heme peroxidase | 0.067 | 1 | 1 |
Onchocerca volvulus | Peroxidasin homolog | 0.067 | 1 | 1 |
Loa Loa (eye worm) | animal heme peroxidase | 0.067 | 1 | 1 |
Onchocerca volvulus | Dual oxidase homolog | 0.067 | 1 | 1 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0046 | 0.0373 | 0.4595 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0029 | 0.0233 |
Entamoeba histolytica | Ser/Thr protein phosphatase, putative | 0.0046 | 0.0373 | 0.4595 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0136 | 0.1305 |
Schistosoma mansoni | peroxidasin | 0.067 | 1 | 1 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0046 | 0.0373 | 0.4595 |
Plasmodium vivax | farnesyltransferase beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Giardia lamblia | Rab geranylgeranyltransferase | 0.0073 | 0.08 | 1 |
Trichomonas vaginalis | transmembrane protein nessy, putative | 0.0023 | 0.0029 | 0.0233 |
Toxoplasma gondii | prenyltransferase and squalene oxidase repeat-containing protein | 0.0052 | 0.0466 | 1 |
Echinococcus multilocularis | protein cysteine N palmitoyltransferase | 0.0023 | 0.0029 | 0.0029 |
Trypanosoma cruzi | lanosterol synthase, putative | 0.0089 | 0.1043 | 1 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0023 | 0.0029 | 0.0233 |
Trypanosoma brucei | multidrug resistance protein E | 0.0028 | 0.0101 | 0.0875 |
Mycobacterium tuberculosis | Halimadienyl diphosphate synthase | 0.0089 | 0.1043 | 1 |
Leishmania major | pentamidine resistance protein 1 | 0.0028 | 0.0101 | 0.1303 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Loa Loa (eye worm) | animal heme peroxidase | 0.067 | 1 | 1 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0279 |
Loa Loa (eye worm) | MBOAT family protein | 0.0023 | 0.0029 | 0.0024 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0029 | 0.0018 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0023 | 0.0029 | 0.0018 |
Echinococcus granulosus | protein prenyltransferase alpha subunit | 0.003 | 0.0136 | 0.0136 |
Entamoeba histolytica | protein farnesyltransferase beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Entamoeba histolytica | vacuolar protein sorting 26 | 0.0023 | 0.0029 | 0.0233 |
Entamoeba histolytica | hypothetical protein | 0.0028 | 0.0101 | 0.1145 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0029 | 0.0113 | 0.1299 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Loa Loa (eye worm) | hhat protein | 0.0023 | 0.0029 | 0.0024 |
Brugia malayi | Blistered cuticle protein 3 | 0.067 | 1 | 1 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0023 | 0.0029 | 0.0029 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0023 | 0.0029 | 0.0029 |
Plasmodium falciparum | serine/threonine protein phosphatase 2B catalytic subunit A | 0.0046 | 0.0373 | 0.4595 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0029 | 0.0024 |
Schistosoma mansoni | protein phosphatase-2b | 0.0046 | 0.0373 | 0.0363 |
Trichomonas vaginalis | geranylgeranyl transferase type beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0023 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0363 | 0.0358 |
Toxoplasma gondii | ABC transporter transmembrane region domain-containing protein | 0.0028 | 0.0101 | 0.1984 |
Echinococcus granulosus | Membrane bound O acyl transferase MBOAT | 0.0023 | 0.0029 | 0.0029 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0029 | 0.0113 | 0.2251 |
Brugia malayi | Animal haem peroxidase family protein | 0.067 | 1 | 1 |
Loa Loa (eye worm) | membrane bound O-acyltransferase domain containing 1 | 0.0023 | 0.0029 | 0.0024 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0279 |
Echinococcus multilocularis | Rab geranylgeranyltransferase, beta subunit | 0.0022 | 0.0011 | 0.0011 |
Echinococcus multilocularis | peroxidasin | 0.067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0052 | 0.0466 | 0.4469 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0023 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0101 | 0.0096 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0029 | 0.0113 | 0.1299 |
Brugia malayi | Animal haem peroxidase family protein | 0.067 | 1 | 1 |
Onchocerca volvulus | 0.067 | 1 | 1 | |
Echinococcus granulosus | membrane bound acyltransferase:hhat | 0.0023 | 0.0029 | 0.0029 |
Echinococcus granulosus | serine:threonine protein phosphatase 2B | 0.0046 | 0.0373 | 0.0373 |
Trypanosoma cruzi | multidrug resistance-associated protein, putative | 0.0028 | 0.0101 | 0.0969 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.003 | 0.0136 | 0.0126 |
Leishmania major | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0265 |
Echinococcus multilocularis | protein farnesyltransferase subunit beta | 0.0052 | 0.0466 | 0.0466 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0046 | 0.0373 | 0.4595 |
Echinococcus granulosus | geranylgeranyl transferase type 2 subunit alpha | 0.003 | 0.0136 | 0.0136 |
Echinococcus granulosus | multidrug resistance associated protein 7 | 0.0028 | 0.0101 | 0.0101 |
Giardia lamblia | Multidrug resistance-associated protein 1 | 0.0028 | 0.0101 | 0.1145 |
Plasmodium vivax | prenyltransferase alpha subunit, putative | 0.0073 | 0.08 | 1 |
Toxoplasma gondii | acyl-CoA:diacylglycerol acyltransferase 1-related enzyme | 0.0023 | 0.0029 | 0.0404 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.003 | 0.0136 | 0.0126 |
Entamoeba histolytica | ATP-binding cassette protein, putative | 0.0028 | 0.0101 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein phosphatase 2B | 0.0046 | 0.0373 | 0.0373 |
Schistosoma mansoni | multidrug resistance protein | 0.0028 | 0.0101 | 0.009 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Trypanosoma cruzi | serine/threonine protein phosphatase, putative | 0.0046 | 0.0373 | 0.3579 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0022 | 0.0011 | 0.0005 |
Trypanosoma brucei | lanosterol synthase | 0.0089 | 0.1043 | 1 |
Onchocerca volvulus | 0.067 | 1 | 1 | |
Giardia lamblia | Rab geranylgeranyltransferase | 0.003 | 0.0136 | 0.159 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0029 | 0.0024 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0029 | 0.0113 | 0.1085 |
Trypanosoma brucei | p-glycoprotein | 0.0028 | 0.0101 | 0.0875 |
Schistosoma mansoni | multidrug resistance protein | 0.0028 | 0.0101 | 0.009 |
Onchocerca volvulus | Peroxidase homolog | 0.067 | 1 | 1 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0029 | 0.0113 | 0.0993 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0101 | 0.0096 |
Echinococcus multilocularis | geranylgeranyl transferase type 2 subunit alpha | 0.003 | 0.0136 | 0.0136 |
Echinococcus multilocularis | membrane bound acyltransferase:hhat | 0.0023 | 0.0029 | 0.0029 |
Brugia malayi | MBOAT family protein | 0.0023 | 0.0029 | 0.0018 |
Trypanosoma cruzi | multidrug resistance-associated protein, putative | 0.0028 | 0.0101 | 0.0969 |
Brugia malayi | Peroxidasin | 0.067 | 1 | 1 |
Echinococcus multilocularis | protein prenyltransferase alpha subunit | 0.003 | 0.0136 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Echinococcus multilocularis | protein farnesyltransferase alpha subunit | 0.0073 | 0.08 | 0.08 |
Leishmania major | ABC-thiol transporter | 0.0028 | 0.0101 | 0.1303 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0029 | 0.0113 | 0.0113 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0029 | 0.0113 | 1 |
Toxoplasma gondii | hypothetical protein | 0.003 | 0.0136 | 0.2755 |
Leishmania major | ATP-binding cassette protein subfamily C, member 1, putative | 0.0028 | 0.0101 | 0.1303 |
Trypanosoma cruzi | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0279 |
Entamoeba histolytica | Ser/Thr protein phosphatase, putative | 0.0046 | 0.0373 | 0.4595 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0029 | 0.0233 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0029 | 0.0113 | 0.0084 |
Entamoeba histolytica | protein farnesyltransferase alpha subunit, putative | 0.0073 | 0.08 | 1 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0023 | 0.0029 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0011 | 0.0102 |
Trypanosoma cruzi | GUP1, putative | 0.0023 | 0.0029 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Leishmania major | ATP-binding cassette protein subfamily C, member 5, putative | 0.0028 | 0.0101 | 0.1303 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0029 | 0.0265 |
Echinococcus multilocularis | serine:threonine protein phosphatase 2B | 0.0046 | 0.0373 | 0.0373 |
Brugia malayi | MBOAT family protein | 0.0023 | 0.0029 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0096 | 0.0091 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit/RAB geranylgeranyl transferase alpha subunit, putative | 0.0043 | 0.0335 | 0.4113 |
Trypanosoma cruzi | serine/threonine protein phosphatase, putative | 0.0046 | 0.0373 | 0.3579 |
Echinococcus multilocularis | serine:threonine protein phosphatase 2B | 0.0046 | 0.0373 | 0.0373 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.003 | 0.0136 | 0.0131 |
Leishmania major | serine/threonine protein phosphatase, putative | 0.0046 | 0.0373 | 0.523 |
Trypanosoma cruzi | geranylgeranyl transferase type II beta subunit, putative | 0.0022 | 0.0011 | 0.0102 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0023 | 0.0029 | 0.0029 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.08 | 0.0795 |
Echinococcus granulosus | peroxidasin | 0.067 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0011 | 0.0102 |
Loa Loa (eye worm) | prenyltransferase alpha subunit repeat containing protein | 0.0073 | 0.08 | 0.0795 |
Echinococcus multilocularis | multidrug resistance associated protein 7 | 0.0028 | 0.0101 | 0.0101 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0029 | 0.0113 | 0.0103 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0023 | 0.0029 | 0.0233 |
Echinococcus multilocularis | Membrane bound O acyl transferase, MBOAT | 0.0023 | 0.0029 | 0.0029 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.003 | 0.0136 | 0.1305 |
Onchocerca volvulus | 0.003 | 0.0136 | 0.0107 | |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0029 | 0.0113 | 0.0113 |
Brugia malayi | Animal haem peroxidase family protein | 0.067 | 1 | 1 |
Loa Loa (eye worm) | prenyltransferase and squalene oxidase repeat family protein | 0.0052 | 0.0466 | 0.0461 |
Leishmania major | lanosterol synthase, putative | 0.0067 | 0.0704 | 1 |
Giardia lamblia | Multidrug resistance-associated protein 1 | 0.0028 | 0.0101 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Schistosoma mansoni | protein phosphatase-2b | 0.0046 | 0.0373 | 0.0363 |
Schistosoma mansoni | multidrug resistance protein | 0.0028 | 0.0101 | 0.009 |
Trichomonas vaginalis | geranylgeranyl transferase type I beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Trypanosoma cruzi | multidrug resistance protein E, putative | 0.0028 | 0.0101 | 0.0969 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0178 |
Echinococcus multilocularis | multidrug resistance associated protein 1 | 0.0028 | 0.0101 | 0.0101 |
Onchocerca volvulus | 0.067 | 1 | 1 | |
Plasmodium vivax | RNA helicase-1, putative | 0.0029 | 0.0113 | 0.1299 |
Plasmodium vivax | serine/threonine protein phosphatase 2B catalytic subunit A, putative | 0.0046 | 0.0373 | 0.4595 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0029 | 0.0113 | 0.1299 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0023 | 0.0029 | 0.0029 |
Trypanosoma brucei | multidrug resistance-associated protein, putative | 0.0028 | 0.0101 | 0.0875 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0023 | 0.0029 | 0.0233 |
Loa Loa (eye worm) | MBOAT family protein | 0.0023 | 0.0029 | 0.0024 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0073 | 0.08 | 1 |
Entamoeba histolytica | ABC transporter, putative | 0.0028 | 0.0101 | 0.1145 |
Trypanosoma brucei | multidrug resistance-associated protein, putative | 0.0028 | 0.0101 | 0.0875 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0011 | 0.0005 |
Trypanosoma cruzi | serine/threonine protein phosphatase 2B catalytic subunit A2, putative | 0.0046 | 0.0373 | 0.3579 |
Loa Loa (eye worm) | hhat protein | 0.0023 | 0.0029 | 0.0024 |
Schistosoma mansoni | leukocyte receptor cluster (lrc) member 4 protein | 0.0023 | 0.0029 | 0.0018 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.159 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.003 | 0.0136 | 0.1215 |
Loa Loa (eye worm) | animal heme peroxidase | 0.067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trypanosoma brucei | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0178 |
Entamoeba histolytica | ATP-binding cassette protein, putative | 0.0028 | 0.0101 | 0.1145 |
Entamoeba histolytica | ATP-binding cassette protein, putative | 0.0028 | 0.0101 | 0.1145 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0023 | 0.0029 | 0.0233 |
Brugia malayi | diacylglycerol acyltransferase | 0.0023 | 0.0029 | 0.0018 |
Giardia lamblia | Prenyltransferase | 0.0052 | 0.0466 | 0.5772 |
Echinococcus granulosus | protein farnesyltransferase subunit beta | 0.0052 | 0.0466 | 0.0466 |
Echinococcus multilocularis | o acyltransferase (membrane bound) domain | 0.0023 | 0.0029 | 0.0029 |
Leishmania major | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0265 |
Brugia malayi | Animal haem peroxidase family protein | 0.067 | 1 | 1 |
Echinococcus granulosus | geranylgeranyl transferase type I beta subunit | 0.0022 | 0.0011 | 0.0011 |
Trypanosoma brucei | protein farnesyltransferase beta subunit | 0.0052 | 0.0466 | 0.4412 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.1305 |
Trypanosoma cruzi | GUP1, putative | 0.0023 | 0.0029 | 0.0279 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0029 | 0.0113 | 0.0113 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0029 | 0.0113 | 0.1299 |
Echinococcus granulosus | lysophospholipid acyltransferase 7 | 0.0023 | 0.0029 | 0.0029 |
Echinococcus granulosus | protein cysteine N palmitoyltransferase | 0.0023 | 0.0029 | 0.0029 |
Trypanosoma brucei | hypothetical protein, conserved | 0.003 | 0.0136 | 0.1215 |
Echinococcus multilocularis | geranylgeranyl transferase type I beta subunit | 0.0022 | 0.0011 | 0.0011 |
Trypanosoma brucei | protein farnesyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.1215 |
Brugia malayi | MBOAT family protein | 0.0023 | 0.0029 | 0.0018 |
Leishmania major | ATP-binding cassette protein subfamily C, member 2, putative | 0.0028 | 0.0101 | 0.1303 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0023 | 0.0029 | 0.0024 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0023 | 0.0029 | 0.0018 |
Entamoeba histolytica | multidrug resistance protein, putative | 0.0028 | 0.0101 | 0.1145 |
Leishmania major | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0265 |
Schistosoma mansoni | multidrug resistance protein | 0.0028 | 0.0101 | 0.009 |
Leishmania major | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0011 | 0.0005 |
Schistosoma mansoni | zinc finger protein | 0.0023 | 0.0029 | 0.0018 |
Echinococcus granulosus | multidrug resistance associated protein 1 | 0.0028 | 0.0101 | 0.0101 |
Plasmodium falciparum | protein farnesyltransferase subunit beta | 0.0052 | 0.0466 | 0.5772 |
Trypanosoma brucei | Protein prenyltransferase alpha subunit repeat, putative | 0.003 | 0.0136 | 0.1215 |
Brugia malayi | Serine/threonine protein phosphatase 2B catalytic subunit 2 | 0.0046 | 0.0373 | 0.0363 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0023 | 0.0029 | 0.0029 |
Onchocerca volvulus | Peroxidasin homolog | 0.067 | 1 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0029 | 0.0113 | 0.1299 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0023 | 0.0029 | 0.0029 |
Toxoplasma gondii | hypothetical protein | 0.0043 | 0.0335 | 0.7126 |
Schistosoma mansoni | protein farnesyltransferase alpha subunit | 0.0073 | 0.08 | 0.079 |
Echinococcus granulosus | protein farnesyltransferase alpha subunit | 0.0073 | 0.08 | 0.08 |
Brugia malayi | Prenyltransferase and squalene oxidase repeat family protein | 0.0052 | 0.0466 | 0.0456 |
Leishmania major | serine/threonine protein phosphatase 2B catalytic subunit A2, putative | 0.0046 | 0.0373 | 0.523 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0029 | 0.0024 |
Onchocerca volvulus | Peroxidase homolog | 0.067 | 1 | 1 |
Brugia malayi | MBOAT family protein | 0.0023 | 0.0029 | 0.0018 |
Brugia malayi | MBOAT family protein | 0.0023 | 0.0029 | 0.0018 |
Echinococcus granulosus | o acyltransferase membrane bound domain | 0.0023 | 0.0029 | 0.0029 |
Giardia lamblia | ABC transporter, putative | 0.0028 | 0.0101 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Leishmania major | farnesyltransferase beta subunit | 0.0052 | 0.0466 | 0.657 |
Plasmodium vivax | conserved Plasmodium protein, unknown function | 0.003 | 0.0127 | 0.1475 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0029 | 0.0113 | 0.1085 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0029 | 0.0113 | 0.1299 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0029 | 0.0024 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0046 | 0.0373 | 0.4595 |
Leishmania major | glycerol uptake protein, putative | 0.0023 | 0.0029 | 0.0265 |
Trichomonas vaginalis | protein farnesyltransferase alpha subunit, putative | 0.0073 | 0.08 | 1 |
Leishmania major | ATP-binding cassette protein subfamily C, member 6, putative | 0.0028 | 0.0101 | 0.1303 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.067 | 1 | 1 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0029 | 0.0113 | 0.0103 |
Entamoeba histolytica | membrane-bound O-acyltransferase (MBOAT ) family protein | 0.0023 | 0.0029 | 0.0233 |
Toxoplasma gondii | hypothetical protein | 0.0023 | 0.0029 | 0.0404 |
Schistosoma mansoni | membrane-bound acyltransferase/hhat | 0.0023 | 0.0029 | 0.0018 |
Brugia malayi | Animal haem peroxidase family protein | 0.067 | 1 | 1 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0029 | 0.0113 | 0.0113 |
Entamoeba histolytica | ATP-binding cassette protein, putative | 0.0028 | 0.0101 | 0.1145 |
Leishmania major | p-glycoprotein e | 0.0028 | 0.0101 | 0.1303 |
Giardia lamblia | Multidrug resistance-associated protein 1 | 0.0028 | 0.0096 | 0.1079 |
Brugia malayi | Hhat protein | 0.0023 | 0.0029 | 0.0018 |
Toxoplasma gondii | acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha | 0.0023 | 0.0029 | 0.0404 |
Loa Loa (eye worm) | ABC transporter transmembrane region family protein | 0.0028 | 0.0101 | 0.0096 |
Trypanosoma cruzi | protein farnesyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.1305 |
Schistosoma mansoni | peroxidasin | 0.067 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0373 | 0.0368 |
Entamoeba histolytica | Rab geranylgeranyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.159 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0023 | 0.0029 | 0.0018 |
Trypanosoma brucei | protein phosphatase 2B, putative | 0.0046 | 0.0373 | 0.3512 |
Trichomonas vaginalis | porcupine, putative | 0.0023 | 0.0029 | 0.0233 |
Loa Loa (eye worm) | MBOAT family protein | 0.0023 | 0.0029 | 0.0024 |
Plasmodium falciparum | protein farnesyltransferase subunit alpha | 0.0073 | 0.08 | 1 |
Schistosoma mansoni | protein farnesyltransferase subunit beta | 0.0052 | 0.0466 | 0.0456 |
Brugia malayi | ABC transporter transmembrane region family protein | 0.0028 | 0.0101 | 0.009 |
Trichomonas vaginalis | geranylgeranyl transferase type II beta subunit, putative | 0.0052 | 0.0466 | 0.5772 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Trypanosoma cruzi | protein farnesyltransferase, putative | 0.0052 | 0.0466 | 0.4469 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0029 | 0.0113 | 0.1479 |
Giardia lamblia | MRP-like ABC transporter | 0.0028 | 0.0101 | 0.1145 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 1 | 1 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0029 | 0.0113 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0113 | 0.0108 |
Brugia malayi | Protein prenyltransferase alpha subunit repeat containing protein | 0.0073 | 0.08 | 0.079 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0029 | 0.0233 |
Plasmodium falciparum | geranylgeranyl transferase type-2 subunit alpha, putative | 0.003 | 0.0136 | 0.159 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0023 | 0.0029 | 0.0233 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0029 | 0.0113 | 0.1479 |
Brugia malayi | multidrug resistance related protein 1 | 0.0028 | 0.0101 | 0.009 |
Toxoplasma gondii | protein phosphatase 2B catalytic subunit, calcineurin family phosphatse superfamily protein | 0.0046 | 0.0373 | 0.7961 |
Schistosoma mansoni | o-acyltransferase (membrane bound) domain containing protein | 0.0023 | 0.0029 | 0.0018 |
Leishmania major | protein farnesyltransferase alpha subunit, putative | 0.003 | 0.0136 | 0.181 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0029 | 0.0233 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 1.5 mM | evaluated for the inhibition of Trypanosoma brucei Phosphoglycerate kinase (PGK) | ChEMBL. | 11063610 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.