Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0374 | 0.0198 | 0.0352 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.1923 | 0.7661 | 0.6813 |
Loa Loa (eye worm) | hypothetical protein | 0.0374 | 0.0198 | 0.0352 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.2033 | 0.8192 | 0.5 |
Brugia malayi | Serotonin receptor | 0.1621 | 0.6205 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1561 | 0.5916 | 0.9518 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.189 | 0.7502 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.1017 | 0.3295 | 0.0891 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1923 | 0.7661 | 0.7025 |
Echinococcus multilocularis | conserved hypothetical protein | 0.2363 | 0.9779 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.1499 | 0.5617 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1491 | 0.5581 | 0.9936 |
Schistosoma mansoni | thyroid hormone receptor | 0.1017 | 0.3295 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.1017 | 0.3295 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0885 | 0.2661 | 0.7952 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1499 | 0.5617 | 0.902 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.1499 | 0.5617 | 0.902 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.2033 | 0.8192 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.