Detailed information for compound 232071

Basic information

Technical information
  • TDR Targets ID: 232071
  • Name: (2R,3S)-N-[(2S,3R)-5-[[amino(methanesulfonami do)methylidene]amino]-3-methyl-1-oxo-1-(1,3-t hiazol-2-ylamino)pentan-2-yl]-6,6,6-trifluoro -3-[formyl(hydroxy)amino]-2-(2-methylpropyl)h exanamide
  • MW: 615.69 | Formula: C22H36F3N7O6S2
  • H donors: 5 H acceptors: 7 LogP: 2.53 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: O=CN([C@H]([C@H](C(=O)N[C@H](C(=O)Nc1nccs1)[C@@H](CC/N=C(\NS(=O)(=O)C)/N)C)CC(C)C)CCC(F)(F)F)O
  • InChi: 1S/C22H36F3N7O6S2/c1-13(2)11-15(16(32(36)12-33)5-7-22(23,24)25)18(34)29-17(19(35)30-21-28-9-10-39-21)14(3)6-8-27-20(26)31-40(4,37)38/h9-10,12-17,36H,5-8,11H2,1-4H3,(H,29,34)(H3,26,27,31)(H,28,30,35)/t14-,15-,16+,17+/m1/s1
  • InChiKey: KIKBZIXCMWKZEI-NCOADZHNSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3S)-N-[(1S,2R)-4-[[amino(methanesulfonamido)methylene]amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)butyl]-6,6,6-trifluoro-3-[formyl(hydroxy)amino]-2-isobutyl-hexanamide
  • (2R,3S)-N-[(1S,2R)-4-[[amino(methanesulfonamido)methylene]amino]-2-methyl-1-[oxo-(2-thiazolylamino)methyl]butyl]-6,6,6-trifluoro-3-[formyl(hydroxy)amino]-2-isobutylhexanamide
  • (2R,3S)-N-[(2S,3R)-5-[[azanyl(methylsulfonylamino)methylidene]amino]-3-methyl-1-oxo-1-(1,3-thiazol-2-ylamino)pentan-2-yl]-6,6,6-trifluoro-3-[hydroxy(methanoyl)amino]-2-(2-methylpropyl)hexanamide
  • (2R,3S)-N-[(2S,3R)-5-[(amino-methanesulfonamidomethylidene)amino]-3-methyl-1-oxo-1-(1,3-thiazol-2-ylamino)pentan-2-yl]-6,6,6-trifluoro-3-(formyl-hydroxyamino)-2-(2-methylpropyl)hexanamide
  • (2R,3S)-N-[(1S,2R)-4-[(amino-methanesulfonamido-methylene)amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)butyl]-6,6,6-trifluoro-3-(formyl-hydroxy-amino)-2-isobutyl-hexanamide
  • (2R,3S)-N-[(1S,2R)-4-[(amino-methanesulfonamidomethylene)amino]-2-methyl-1-[oxo-(2-thiazolylamino)methyl]butyl]-6,6,6-trifluoro-3-(formyl-hydroxyamino)-2-isobutylhexanamide
  • (2R,3S)-N-[(2S,3R)-5-[[amino-(methylsulfonylamino)methylidene]amino]-3-methyl-1-oxo-1-(1,3-thiazol-2-ylamino)pentan-2-yl]-6,6,6-trifluoro-3-(hydroxy-methanoyl-amino)-2-(2-methylpropyl)hexanamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) Starlite/ChEMBL References
Homo sapiens ADAM metallopeptidase domain 17 Starlite/ChEMBL References
Homo sapiens matrix metallopeptidase 3 (stromelysin 1, progelatinase) Starlite/ChEMBL References
Homo sapiens matrix metallopeptidase 1 (interstitial collagenase) Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132656 All targets in OG5_132656
Echinococcus granulosus Blood coagulation inhibitor Disintegrin Get druggable targets OG5_132656 All targets in OG5_132656
Echinococcus granulosus adam 17 protease Get druggable targets OG5_132656 All targets in OG5_132656
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin Get druggable targets OG5_132656 All targets in OG5_132656
Schistosoma japonicum ko:K06059 a disintegrin and metalloproteinase domain 17, putative Get druggable targets OG5_132656 All targets in OG5_132656
Echinococcus multilocularis adam 17 protease Get druggable targets OG5_132656 All targets in OG5_132656
Schistosoma mansoni ADAM17 peptidase (M12 family) Get druggable targets OG5_132656 All targets in OG5_132656
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Disintegrin family protein ADAM metallopeptidase domain 17 824 aa 724 aa 27.4 %
Echinococcus granulosus matrix metallopeptidase 7 M10 family matrix metallopeptidase 3 (stromelysin 1, progelatinase) 477 aa 431 aa 34.6 %
Brugia malayi Matrixin family protein matrix metallopeptidase 1 (interstitial collagenase) 403 aa 401 aa 27.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis survival motor neuron protein 1 0.1181 0.116 0.116
Echinococcus granulosus sentrin specific protease 8 0.0077 0.0063 0.0063
Leishmania major cytochrome p450-like protein 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0059 0.0045 0.0827
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0003 0.0003
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0047 0.0032 0.0044
Brugia malayi Cathepsin L-like precursor 0.002 0.0006 0.0006
Echinococcus multilocularis muscleblind protein 0.0727 0.0709 0.0709
Echinococcus granulosus DNA methyltransferase 2, putative 0.0019 0.0005 0.0005
Brugia malayi ADAM-TS Spacer 1 family protein 0.0017 0.0002 0.0002
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0037 0.0023 0.0029
Brugia malayi beta-lactamase family protein 0.0021 0.0007 0.0007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0147 0.0132 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0241 0.0225 0.0302
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0003 0.0003
Trypanosoma brucei ABC transporter, putative 0.0019 0.0005 0.0007
Onchocerca volvulus 0.0017 0.0003 0.0067
Echinococcus multilocularis expressed protein 0.0026 0.0011 0.0011
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0025 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0468 0.0451 0.0451
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0006 0.0006
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0025 0.0011 0.0011
Schistosoma mansoni transcription factor btf3 0.0025 0.0011 0.0011
Echinococcus granulosus GA binding protein alpha chain 0.0078 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0092 0.0092
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0006 0.0006
Schistosoma mansoni z-protein (S1r protein) 0.0037 0.0023 0.0023
Schistosoma mansoni ferritin 0.0026 0.0011 0.0011
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.001 0.0012
Echinococcus multilocularis subfamily M12B unassigned peptidase 0.0022 0.0008 0.0008
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0003 0.0003
Schistosoma mansoni tsg101-related 0.0056 0.0041 0.0041
Brugia malayi GRF zinc finger family protein 0.0064 0.0049 0.0049
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans aldehyde dehydrogenase 0.0192 0.0177 0.3303
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0016 0.0001 0.0012
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0017 0.0003 0.0003
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0003 0.0003
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Chlamydia trachomatis deubiquitinase/deneddylase Dub2 0.0025 0.0011 0.0292
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0047 0.0032 0.1147
Brugia malayi hypothetical protein 0.0016 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.002 0.0006 0.0085
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0048 0.102
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Leishmania major mitochondrial DNA polymerase beta 0.051 0.0492 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0048 0.102
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0147 0.0132 0.0132
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0001 0.0001
Giardia lamblia Kinase, PLK 0.0188 0.0173 0.6112
Brugia malayi tailless protein 0.0069 0.0055 0.0055
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0124 0.0109 0.2035
Brugia malayi Protein kinase domain containing protein 0.0104 0.0089 0.0089
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.0011 0.023
Trichomonas vaginalis esterase, putative 0.0021 0.0007 0.0146
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Onchocerca volvulus 0.0316 0.03 0.641
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0016 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0058 0.0044 0.0938
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0003 0.0003
Echinococcus granulosus lysine specific demethylase 5A 0.0128 0.0113 0.0113
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0021 0.0007 0.001
Trypanosoma brucei MATE efflux family protein, putative 0.0066 0.0052 0.007
Mycobacterium leprae Conserved hypothetical protein 0.002 0.0006 0.0085
Trichomonas vaginalis ap endonuclease, putative 0.0027 0.0012 0.026
Loa Loa (eye worm) beta-lactamase 0.0021 0.0007 0.0007
Trypanosoma brucei DNA topoisomerase ii 0.0057 0.0042 0.0057
Brugia malayi hypothetical protein 0.0375 0.0359 0.0359
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0051 0.1805
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0102 0.0087 0.0087
Echinococcus multilocularis DNA topoisomerase 3 beta 1 0.013 0.0115 0.0115
Echinococcus multilocularis lamin 0.0054 0.004 0.004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0129 0.0114 0.0114
Loa Loa (eye worm) hypothetical protein 0.0088 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0316 0.03 0.03
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0092 0.0092
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0147 0.0132 0.0132
Echinococcus granulosus dnaJ subfamily C 6 0.0105 0.009 0.009
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.1181 0.116 0.116
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0003 0.0003
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0023 0.0029
Brugia malayi jmjC domain containing protein 0.0032 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Brugia malayi Cytochrome P450 family protein 0.0051 0.0037 0.0037
Leishmania major modification methylase-like protein 0.0019 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0079 0.0064 0.0087
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0073 0.0058 0.0058
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0113 0.0098 0.346
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi Nuclear hormone receptor E75 0.0069 0.0055 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0094 0.0094
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0032 0.0017 0.0023
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0004 0.0094
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0081 0.0066 0.0066
Giardia lamblia DNA damage repair protein 0.0023 0.0008 0.0291
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0051 0.0067
Brugia malayi DIX domain containing protein 0.0017 0.0003 0.0003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.002 0.0437
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0147 0.0132 0.0132
Plasmodium falciparum DNA repair protein REV1, putative 0.0023 0.0008 0.0008
Chlamydia trachomatis DNA topoisomerase I 0.0292 0.0276 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0147 0.0132 0.0132
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0003 0.0002
Schistosoma mansoni protein phosphatase 2C 0.0032 0.0017 0.0017
Echinococcus multilocularis Niemann Pick C1 protein 0.006 0.0045 0.0045
Mycobacterium ulcerans putative regulatory protein 0.0177 0.0162 0.3027
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0016 0.0001 0.0002
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Wolbachia endosymbiont of Brugia malayi topoisomerase IA, TopA 0.0292 0.0276 1
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0069 0.0055 0.0055
Brugia malayi ADAMTS-like protease 0.0017 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.004 0.0026 0.0546
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0233
Onchocerca volvulus Globin homolog 0.0026 0.0011 0.0239
Echinococcus granulosus disintegrin and metalloproteinase 0.0022 0.0008 0.0008
Echinococcus multilocularis adam 0.0039 0.0024 0.0024
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0017 0.0003 0.0033
Brugia malayi PHD-finger family protein 0.0023 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0064 0.005 0.005
Echinococcus multilocularis neutral alpha glucosidase AB 0.013 0.0115 0.0115
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0063 0.0048 0.0048
Brugia malayi nuclear hormone receptor family member nhr-6 0.0069 0.0055 0.0055
Trypanosoma cruzi membrane transporter protein, putative 0.0066 0.0052 0.0068
Schistosoma mansoni regulator of G protein signaling 0.0037 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0077 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0088 0.0074 0.0074
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0027 0.0012 0.0431
Schistosoma mansoni amine GPCR 0.0017 0.0003 0.0003
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Echinococcus multilocularis dnaJ subfamily B 0.177 0.1745 0.1745
Toxoplasma gondii SWI2/SNF2-containing protein 0.0042 0.0028 0.0028
Leishmania major cathepsin L-like protease 0.002 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0032 0.0032
Mycobacterium tuberculosis Probable dehydrogenase 0.0016 0.0001 0.0012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0024 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0101 0.0086 0.1593
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0129 0.0114 0.0114
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0003 0.0052
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0034 0.0727
Onchocerca volvulus 0.0026 0.0011 0.0239
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.002 0.0006 0.0097
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.035 0.0334 0.0334
Toxoplasma gondii aldehyde dehydrogenase 0.0192 0.0177 0.0177
Loa Loa (eye worm) cysteine protease 0.002 0.0006 0.0006
Leishmania major acetyl-CoA synthetase, putative 0.0017 0.0003 0.0002
Schistosoma mansoni ferritin light chain 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0486 0.0468 1
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0001 0.0001
Echinococcus multilocularis muscleblind protein 1 0.0727 0.0709 0.0709
Schistosoma mansoni jun-related protein 0.0066 0.0051 0.0051
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0024 0.0024
Echinococcus multilocularis 0.002 0.0006 0.0006
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0064 0.0049 0.0065
Schistosoma mansoni microtubule-associated protein tau 0.3028 0.2995 0.2995
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0032 0.0017 0.0017
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0016 0.0001 0.0001
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Toxoplasma gondii target of rapamycin (TOR), putative 0.0035 0.002 0.002
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Loa Loa (eye worm) hypothetical protein 0.0077 0.0062 0.0062
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0001 0.0012
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0008 0.0011
Loa Loa (eye worm) MH1 domain-containing protein 0.0032 0.0018 0.0018
Mycobacterium ulcerans hydrolase 0.0103 0.0088 0.1638
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0069 0.0055 0.0055
Brugia malayi Thioredoxin reductase 0.0049 0.0035 0.0035
Echinococcus multilocularis lamin dm0 0.0054 0.004 0.004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.0034 0.0727
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0003 0.0004
Brugia malayi hypothetical protein 0.0077 0.0063 0.0063
Echinococcus granulosus adam 0.0039 0.0024 0.0024
Trypanosoma brucei cytosine-specific DNA methylase, putative 0.0019 0.0005 0.0007
Schistosoma mansoni axis inhibition protein axin 0.002 0.0006 0.0006
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.002 0.0006 0.0097
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0135 0.012 0.224
Trichomonas vaginalis set domain proteins, putative 0.0485 0.0468 1
Echinococcus granulosus hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis disco interacting protein 2 0.004 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0115 0.2461
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0001 0.0001
Brugia malayi Smad1 0.0032 0.0018 0.0018
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.004 0.004
Brugia malayi MH1 domain containing protein 0.0018 0.0004 0.0004
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0003 0.0003
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0072 0.0057 0.0075
Echinococcus granulosus TGF beta signal transducer SmadC 0.0032 0.0018 0.0018
Schistosoma mansoni lozenge 0.004 0.0025 0.0025
Leishmania major protein kinase, putative 0.0071 0.0057 0.0075
Schistosoma mansoni DNA topoisomerase type I 0.7471 0.7411 0.7411
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Schistosoma mansoni ran 0.0053 0.0039 0.0039
Onchocerca volvulus Cathepsin L homolog 0.002 0.0006 0.0119
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0027 0.0012 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0003 0.0003
Brugia malayi polybromodomain protein 0.0019 0.0004 0.0004
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0057 0.0042 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0073 0.1555
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0059 0.0045 0.0815
Mycobacterium ulcerans acyl-CoA synthetase 0.0059 0.0045 0.0815
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) pax transcription factor protein 2 0.0478 0.0461 0.0461
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0147 0.0132 0.0132
Giardia lamblia Reductase, putative 0.0016 0.0001 0.0048
Loa Loa (eye worm) hypothetical protein 0.0014 0.00000014189 0.00000014189
Brugia malayi nuclear receptor NHR-88 0.0069 0.0055 0.0055
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0019 0.0005 0.0005
Leishmania major cathepsin L-like protease 0.002 0.0006 0.0006
Onchocerca volvulus Bile acid receptor homolog 0.0147 0.0132 0.2807
Echinococcus granulosus kelch ECH associated protein 1 like 0.0091 0.0077 0.0077
Onchocerca volvulus 0.0017 0.0003 0.0067
Plasmodium falciparum glutathione reductase 0.0017 0.0003 0.0003
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0088 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0062 0.0048 0.0048
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0216 0.02 0.02
Trichomonas vaginalis adenylate cyclase, putative 0.0062 0.0048 0.102
Brugia malayi neuropeptide F receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0031 0.0031
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0017 0.0003 0.0033
Echinococcus multilocularis caspase 8 0.0088 0.0073 0.0073
Entamoeba histolytica deoxycytidyl transferase, putative 0.0073 0.0058 0.2053
Brugia malayi Hypothetical 22.2 kDa protein C28F5.2 in chromosome II, putative 0.0026 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0012
Echinococcus multilocularis caspase 3 0.0144 0.0129 0.0129
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.002 0.0006 0.0097
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0017 0.0022
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.077 0.0751 0.0751
Schistosoma mansoni hypothetical protein 0.0026 0.0011 0.0011
Plasmodium vivax DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0005 0.0005
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0053 0.0039 0.0039
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0061 0.0081
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Toxoplasma gondii peptidylprolyl isomerase 0.0052 0.0037 0.0037
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0103 0.0088 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0031
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0017 0.0364
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0003 0.0045
Treponema pallidum DNA topoisomerase I (topA) 0.0292 0.0276 0.9765
Schistosoma mansoni hypothetical protein 0.0041 0.0026 0.0026
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0016 0.0001 0.0001
Echinococcus granulosus DNA topoisomerase 3 beta 1 0.013 0.0115 0.0115
Brugia malayi hypothetical protein 0.0112 0.0097 0.0097
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0059 0.0045 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0121
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0023 0.0023
Echinococcus multilocularis lysosomal alpha glucosidase 0.0529 0.0511 0.0511
Leishmania major basic transcription factor 3a, putative 0.0025 0.0011 0.0013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) fli-1 protein 0.0237 0.0222 0.0222
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.002 0.0006 0.0006
Trichomonas vaginalis penicillin-binding protein, putative 0.0021 0.0007 0.0146
Schistosoma mansoni myst-related protein 0.0018 0.0004 0.0004
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0022 0.0008 0.0008
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0052 0.0037 0.0048
Echinococcus granulosus caspase 8 0.0088 0.0073 0.0073
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0147 0.0132 0.0132
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0076 0.0062 0.0062
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Leishmania major 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.001 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.0027 0.0012 0.026
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0011 0.0241
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus dual specificity 0.0104 0.0089 0.0089
Trypanosoma brucei DNA polymerase IV, putative 0.0092 0.0078 0.0105
Plasmodium falciparum cysteine proteinase falcipain 2a 0.002 0.0006 0.0006
Onchocerca volvulus 0.0062 0.0048 0.1018
Brugia malayi DNA topoisomerase III beta-1 0.013 0.0115 0.0115
Entamoeba histolytica hypothetical protein 0.0216 0.02 0.7084
Schistosoma mansoni nuclear receptor nhr-48 0.0069 0.0055 0.0055
Plasmodium falciparum DNA gyrase subunit B 0.0057 0.0042 0.0042
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0115 0.2461
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0012
Echinococcus multilocularis adam 17 protease 0.0223 0.0207 0.0207
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.002 0.0006 0.0097
Echinococcus multilocularis dnaJ subfamily C 6 0.0105 0.009 0.009
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0121
Loa Loa (eye worm) hypothetical protein 0.0077 0.0063 0.0063
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0382
Trypanosoma cruzi SUMO1/Ulp2, putative 0.0025 0.0011 0.0013
Echinococcus multilocularis inositol monophosphatase 1 0.0113 0.0098 0.0098
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0006 0.0201
Loa Loa (eye worm) hypoxia-induced factor 1 0.0742 0.0723 0.0723
Leishmania major DNA topoisomerase 1A 0.025 0.0234 0.0314
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi bHLH-PAS transcription factor 0.0177 0.0162 0.0162
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0041 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0018 0.0004 0.0137
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0077 0.0063 0.1335
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0023 0.0023
Schistosoma mansoni netrin receptor unc5 0.0015 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0003 0.0003
Loa Loa (eye worm) intermediate filament protein 0.0054 0.004 0.004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.002 0.0437
Loa Loa (eye worm) hypothetical protein 0.0044 0.003 0.003
Schistosoma mansoni prokaryotic DNA topoisomerase 0.013 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0102 0.0087 0.0087
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0006 0.0006
Brugia malayi nuclear receptor RXR 0.0069 0.0055 0.0055
Brugia malayi cytochrome P450 0.002 0.0006 0.0006
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Echinococcus granulosus intermediate filament protein 0.0054 0.004 0.004
Onchocerca volvulus Cathepsin L homolog 0.002 0.0006 0.0119
Trichomonas vaginalis Sentrin-specific protease, putative 0.0077 0.0063 0.1335
Loa Loa (eye worm) histone methyltransferase 0.005 0.0035 0.0035
Echinococcus granulosus snurportin 1 0.077 0.0751 0.0751
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0147 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0049 0.0034 0.0034
Loa Loa (eye worm) papain family cysteine protease containing protein 0.002 0.0006 0.0006
Leishmania major hypothetical protein, conserved 0.0215 0.02 0.0268
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Echinococcus granulosus ATP binding cassette sub family G 0.0019 0.0005 0.0005
Trypanosoma brucei oxidoreductase-like protein 0.0016 0.0001 0.0002
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0003 0.0003
Chlamydia trachomatis DNA gyrase subunit B 0.0057 0.0042 0.1438
Trichomonas vaginalis helicase, putative 0.0035 0.002 0.0437
Leishmania major cathepsin L-like protease 0.0076 0.0061 0.0081
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0027 0.0502
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0047 0.0032 0.0042
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0003 0.0003
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0003 0.0003
Brugia malayi Bromodomain containing protein 0.0023 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0234
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.002 0.0437
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0147 0.0132 0.0132
Loa Loa (eye worm) runx1 0.004 0.0025 0.0025
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Trypanosoma brucei DNA topoisomerase IA, putative 0.025 0.0234 0.0315
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0003 0.0003
Echinococcus granulosus zinc finger protein 0.0023 0.0009 0.0009
Echinococcus granulosus Smad4 0.0032 0.0018 0.0018
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.002 0.0006 0.0097
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0003 0.0045
Schistosoma mansoni smad1 5 8 and 0.0032 0.0018 0.0018
Entamoeba histolytica acetyltransferase, GNAT family 0.0157 0.0142 0.5018
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0037 0.0023 0.0031
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0047 0.0032 0.0032
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0016 0.0001 0.0027
Brugia malayi larval opioid receptor 0.0017 0.0003 0.0003
Plasmodium vivax glutathione reductase, putative 0.0049 0.0035 0.0035
Schistosoma mansoni amine GPCR 0.0017 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis rotamase, putative 0.0052 0.0037 0.0791
Schistosoma mansoni hypothetical protein 0.0105 0.009 0.009
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0016 0.0001 0.0027
Entamoeba histolytica transcription factor BTF3, putative 0.0025 0.0011 0.0377
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0016 0.0002 0.0023
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0094 0.0094
Onchocerca volvulus 0.0016 0.0001 0.0027
Trichomonas vaginalis antibiotic synthetase, putative 0.0017 0.0003 0.0066
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0003 0.0003
Brugia malayi neuropeptide F receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0071 0.0057 0.1208
Trypanosoma brucei polo-like protein kinase 0.0188 0.0173 0.0233
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0015 0.0015
Trichomonas vaginalis maltase-glucoamylase, putative 0.0048 0.0034 0.0727
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Brugia malayi Disco-interacting protein 2 homolog 0.0037 0.0023 0.0023
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0064 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.002 0.0006 0.0085
Trypanosoma cruzi DNA topoisomerase III, putative 0.013 0.0115 0.0153
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0053 0.0039 0.0052
Schistosoma mansoni ferritin 0.0026 0.0011 0.0011
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.002 0.0006 0.0085
Schistosoma mansoni ap endonuclease 0.0027 0.0012 0.0012
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0053 0.0038 0.0038
Echinococcus multilocularis expressed protein 0.0053 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0216 0.02 0.7084
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0007 0.0007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0382
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis expressed conserved protein 0.0056 0.0042 0.0042
Schistosoma mansoni phosphatidylserine receptor 0.0032 0.0017 0.0017
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0027 0.0502
Onchocerca volvulus 0.0069 0.0055 0.1163
Echinococcus granulosus inositol monophosphatase 1 0.0113 0.0098 0.0098
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.002 0.0006 0.0097
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0037 0.0023 0.0817
Echinococcus multilocularis beta LACTamase domain containing family member 0.0021 0.0007 0.0007
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0025 0.0011 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0147 0.0132 0.0132
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0006 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0234
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0053 0.0039 0.005
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0007 0.0007
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0027 0.0012 0.0012
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0188 0.0173 0.0173
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0002 0.0001
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Schistosoma mansoni dishevelled 0.0017 0.0003 0.0003
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0016 0.0001 0.0002
Plasmodium falciparum metacaspase 1 0.0088 0.0073 0.0073
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Trypanosoma brucei cytochrome P450, putative 0.0047 0.0032 0.0043
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Schistosoma mansoni ferritin 0.0026 0.0011 0.0011
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0035 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0053 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Echinococcus multilocularis flap endonuclease 1 0.0027 0.0012 0.0012
Echinococcus multilocularis apoptotic protease activating factor 1 0.0112 0.0097 0.0097
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.002 0.0437
Trichomonas vaginalis D-aminoacylase, putative 0.0021 0.0007 0.0146
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.002 0.0006 0.0006
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0088 0.0073 0.0073
Schistosoma mansoni nuclear receptor 0.0069 0.0055 0.0055
Onchocerca volvulus 0.0112 0.0097 0.2064
Plasmodium vivax DNA gyrase subunit B, putative 0.0057 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.003 0.003
Echinococcus multilocularis protein dispatched 1 0.0029 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0003 0.0003
Entamoeba histolytica serine/threonine protein kinase, putative 0.0188 0.0173 0.6112
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0006 0.0006
Brugia malayi Globin family protein 0.0026 0.0011 0.0011
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.005 0.005
Trypanosoma cruzi metacaspase, putative 0.0088 0.0073 0.0096
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0051 0.0067
Mycobacterium tuberculosis Probable oxidoreductase 0.0125 0.011 0.2055
Brugia malayi Probable DNA topoisomerase II 0.0057 0.0042 0.0042
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0107 0.0092 0.0092
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0192 0.0177 0.3311
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Trypanosoma brucei hypothetical protein, conserved 0.0215 0.02 0.027
Loa Loa (eye worm) DIX domain-containing protein 0.0017 0.0003 0.0003
Leishmania major GTP-binding protein, putative 0.0053 0.0039 0.005
Schistosoma mansoni tsg101-related 0.0046 0.0031 0.0031
Schistosoma mansoni nuclear hormone receptor 0.0069 0.0055 0.0055
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0048 0.0063
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Echinococcus granulosus ferritin 0.0026 0.0011 0.0011
Echinococcus multilocularis rho GTPase activating protein 20 0.0257 0.0241 0.0241
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.002 0.0006 0.0085
Onchocerca volvulus 0.002 0.0006 0.0119
Giardia lamblia DNA topoisomerase II 0.0057 0.0042 0.149
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0003 0.0003
Schistosoma mansoni ABC transporter 0.0016 0.0002 0.0002
Echinococcus multilocularis smad 0.0032 0.0018 0.0018
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0048 0.0048
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0035 0.0045
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0053 0.0038 0.0817
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.005 0.0035 0.0035
Echinococcus multilocularis dual specificity 0.0104 0.0089 0.0089
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0032 0.0042
Trypanosoma cruzi ISWI complex protein 0.0016 0.0002 0.0001
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0006 0.0006
Schistosoma mansoni alpha-glucosidase 0.0447 0.043 0.043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.006 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0023
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0048 0.0063
Toxoplasma gondii oxidoreductase, putative 0.0016 0.0001 0.0001
Plasmodium vivax SET domain protein, putative 0.0064 0.005 0.005
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0053 0.0039 0.0039
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.0084 0.0114
Trichomonas vaginalis flap endonuclease-1, putative 0.0027 0.0012 0.0262
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0241 0.0225 0.0302
Brugia malayi RNA recognition motif domain containing protein 0.0109 0.0094 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0031
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0007 0.0007
Schistosoma mansoni retinoic acid receptor RXR 0.0147 0.0132 0.0132
Brugia malayi Hemopexin family protein 0.012 0.0105 0.0105
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0147 0.0132 0.0132
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0027 0.0012 0.0015
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0042 0.0057
Loa Loa (eye worm) matrix metalloproteinase 0.0085 0.007 0.007
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0048 0.0034 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0147 0.0132 0.0132
Trypanosoma cruzi polo-like protein kinase, putative 0.0188 0.0173 0.0231
Trichomonas vaginalis sucrase-isomaltase, putative 0.013 0.0115 0.2461
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0171 0.0156 0.0156
Mycobacterium tuberculosis Conserved hypothetical protein 0.0073 0.0058 0.1077
Echinococcus granulosus sterol regulatory element binding protein 0.0026 0.0011 0.0011
Brugia malayi DnaJ domain containing protein 0.0105 0.009 0.009
Plasmodium vivax hypothetical protein, conserved 0.0088 0.0073 0.0073
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0019 0.0005 0.0005
Schistosoma mansoni biogenic amine receptor 0.0017 0.0003 0.0003
Trypanosoma brucei membrane transporter protein, putative 0.0066 0.0052 0.007
Loa Loa (eye worm) phosphatidylinositol 3 0.0047 0.0032 0.0032
Trypanosoma brucei metacaspase 5, putative 0.0088 0.0073 0.0098
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Brugia malayi Cathepsin L-like precursor 0.002 0.0006 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0052 0.0037 0.0048
Loa Loa (eye worm) phosphatidylinositol 3 0.0016 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0121
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.002 0.0437
Echinococcus granulosus caspase 3 0.0144 0.0129 0.0129
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0003 0.0003
Schistosoma mansoni retinal dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi Ets-domain containing protein 0.0078 0.0064 0.0064
Plasmodium falciparum cysteine proteinase falcipain 2b 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0018 0.0004 0.0004
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0099 0.0084 0.1799
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0147 0.0132 0.2807
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.025 0.0234 0.4993
Brugia malayi Nuclear hormone receptor-like 1 0.0077 0.0063 0.0063
Brugia malayi Dehydrogenases, short chain protein 30 0.0016 0.0001 0.0001
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.001 0.0172
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0027 0.0012 0.0431
Echinococcus multilocularis oxidoreductase 0.0016 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Onchocerca volvulus 0.0016 0.0001 0.0027
Leishmania major acetyl-CoA synthetase, putative 0.0017 0.0003 0.0002
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0003 0.0003
Loa Loa (eye worm) dehydrogenase 0.0016 0.0001 0.0001
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0025 0.0011 0.0011
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0069 0.0055 0.0055
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.0026 0.0011 0.0011
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0003 0.0027
Brugia malayi hypothetical protein 0.0066 0.0051 0.0051
Onchocerca volvulus Cathepsin F homolog 0.002 0.0006 0.0119
Onchocerca volvulus 0.0017 0.0003 0.0067
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0016 0.0343
Echinococcus granulosus lysine specific demethylase 6a 0.0032 0.0017 0.0017
Loa Loa (eye worm) matrixin family protein 0.0188 0.0173 0.0173
Trichomonas vaginalis ferritin, putative 0.0026 0.0011 0.0243
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0003 0.0003
Brugia malayi Globin family protein 0.0026 0.0011 0.0011
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0124 0.0109 0.0109
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0188 0.0173 0.0173
Loa Loa (eye worm) MH2 domain-containing protein 0.0032 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor 0.0069 0.0055 0.0055
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0003 0.0003
Echinococcus multilocularis phd:f box containing protein 0.0032 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Brugia malayi Isocitrate dehydrogenase 0.0063 0.0048 0.0048
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0147 0.0132 0.0132
Plasmodium vivax sentrin-specific protease 1, putative 0.0025 0.0011 0.0011
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0006 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0063 0.0048 0.0048
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0003 0.0003
Trypanosoma cruzi metacaspase, putative 0.0088 0.0073 0.0096
Schistosoma mansoni hypothetical protein 0.0046 0.0031 0.0031
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0017 0.0003 0.0002
Onchocerca volvulus 0.0054 0.004 0.0845
Mycobacterium ulcerans beta-lactamase 0.0021 0.0007 0.0103
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.002 0.0006 0.0085
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0003 0.0003
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0098 0.0132
Trypanosoma cruzi DNA topoisomerase III, putative 0.0257 0.0241 0.0323
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0017 0.0003 0.0045
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.0007 0.0007
Leishmania major trypanothione reductase 0.0049 0.0035 0.0045
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0041 0.0026 0.0026
Onchocerca volvulus 0.0059 0.0045 0.0952
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0016 0.0001 0.0001
Schistosoma mansoni tsg101-related 0.0056 0.0041 0.0041
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0012
Echinococcus granulosus neuropeptide s receptor 0.0287 0.0271 0.0271
Echinococcus granulosus GPCR family 2 0.0041 0.0026 0.0026
Brugia malayi beta-NAC-like protein 0.0025 0.0011 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0048 0.0034 0.1205
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0057 0.0042 0.0042
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.002 0.0006 0.0085
Echinococcus granulosus apoptotic protease activating factor 1 0.0112 0.0097 0.0097
Echinococcus granulosus fmrfamide receptor 0.0017 0.0003 0.0003
Toxoplasma gondii hypothetical protein 0.0082 0.0068 0.0068
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0052 0.0068
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.0021 0.0007 0.0007
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0171 0.0156 0.3329
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.002 0.0006 0.0085
Onchocerca volvulus 0.0085 0.007 0.1493
Schistosoma mansoni smad1 5 8 and 0.0032 0.0018 0.0018
Brugia malayi glutathione reductase 0.0049 0.0035 0.0035
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis ATP binding cassette sub family G 0.0019 0.0005 0.0005
Schistosoma mansoni DNA polymerase IV / kappa 0.0023 0.0008 0.0008
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0011
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0027 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Brugia malayi acetyltransferase, GNAT family protein 0.0582 0.0564 0.0564
Giardia lamblia Histone acetyltransferase GCN5 0.0157 0.0142 0.5018
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Brugia malayi Glycosyl hydrolases family 31 protein 0.013 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0098 0.181
Schistosoma mansoni biogenic amine receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) DNA topoisomerase III 0.0257 0.0241 0.0241
Trypanosoma cruzi target of rapamycin kinase 3 0.0037 0.0023 0.0029
Schistosoma mansoni neuropeptide receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0007 0.0007
Echinococcus granulosus lamin dm0 0.0054 0.004 0.004
Onchocerca volvulus 0.0016 0.0001 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0034 0.0727
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0003 0.0003
Loa Loa (eye worm) Ulp1 protease 0.0077 0.0063 0.0063
Brugia malayi Pre-SET motif family protein 0.0427 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0023
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0017 0.0003 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0147 0.0132 0.0132
Schistosoma mansoni intermediate filament proteins 0.0054 0.004 0.004
Echinococcus multilocularis GPCR, family 2 0.0041 0.0026 0.0026
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0062 0.0048 0.102
Toxoplasma gondii Ulp1 protease family, C-terminal catalytic domain-containing protein 0.0025 0.0011 0.0011
Mycobacterium ulcerans DNA topoisomerase I 0.025 0.0234 0.4374
Onchocerca volvulus 0.0037 0.0023 0.0491
Loa Loa (eye worm) hypothetical protein 0.0375 0.0359 0.0359
Toxoplasma gondii cytochrome p450 superfamily protein 0.002 0.0006 0.0006
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.0161 0.3443
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0044 0.0044
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0016 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0044 0.003 0.003
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0172 0.0157 0.0157
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.051 0.0492 0.0662
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0016 0.0001 0.0001
Mycobacterium ulcerans hypothetical protein 0.0025 0.001 0.0172
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0188 0.0173 0.0231
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.0085 0.007 0.007
Brugia malayi Death domain containing protein 0.0015 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.002 0.0006 0.0085
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0147 0.0132 0.0132
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0003 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0085 0.007 0.007
Treponema pallidum bacterioferrin (TpF1) 0.0026 0.0011 0.0307
Schistosoma mansoni hypothetical protein 0.0041 0.0026 0.0026
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.004 0.0026 0.0026
Echinococcus multilocularis musashi 0.0054 0.004 0.004
Mycobacterium leprae PROBABLE HYDROLASE 0.0103 0.0088 0.1638
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0004
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0003 0.0003
Schistosoma mansoni bromodomain containing protein 0.0023 0.0009 0.0009
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0188 0.0173 0.0173
Trypanosoma cruzi cysteine peptidase, Clan CA, family C48, putative 0.0025 0.0011 0.0013
Leishmania major cathepsin L-like protease 0.0076 0.0061 0.0081
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma brucei mitochondrial DNA polymerase beta 0.051 0.0492 0.0664
Echinococcus granulosus ATPase family AAA domain containing protein 2B 0.0014 0.00000014189 0.00000014189
Loa Loa (eye worm) Smad1 0.0032 0.0018 0.0018
Echinococcus granulosus ubiquitin specific protease 41 0.0037 0.0023 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0233
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0057 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni transcription factor LCR-F1 0.0216 0.02 0.02
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0035 0.0035
Onchocerca volvulus 0.0017 0.0003 0.0067
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0107 0.0092 0.0092
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0032 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Leishmania major cathepsin L-like protease 0.002 0.0006 0.0006
Plasmodium falciparum steroid dehydrogenase, putative 0.0016 0.0001 0.0001
Echinococcus granulosus subfamily M12B unassigned peptidase 0.0022 0.0008 0.0008
Mycobacterium ulcerans bacterioferritin BfrA 0.0026 0.0011 0.0189
Echinococcus multilocularis tar DNA binding protein 0.0109 0.0094 0.0094
Toxoplasma gondii hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni alpha-glucosidase 0.0447 0.043 0.043
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0072 0.0057 0.0057
Brugia malayi PAS domain containing protein 0.024 0.0224 0.0224
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0113 0.0098 0.2087
Leishmania major hypothetical protein, conserved 0.0066 0.0052 0.0068
Schistosoma mansoni DNA topoisomerase type I 0.7471 0.7411 0.7411
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0059 0.0045 0.0815
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0051 0.0051
Trypanosoma brucei importin beta-1 subunit, putative 0.0072 0.0057 0.0078
Trypanosoma brucei DNA topoisomerase type IB small subunit 0.4044 0.4005 0.5404
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.0026 0.0011 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.02 0.0268
Loa Loa (eye worm) matrixin family protein 0.0205 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.0031 0.0017 0.0017
Trypanosoma brucei membrane transporter protein, putative 0.0066 0.0052 0.007
Loa Loa (eye worm) transcription factor SMAD2 0.0475 0.0458 0.0458
Toxoplasma gondii histone lysine methyltransferase SET1 0.0308 0.0292 0.0292
Plasmodium falciparum basic transcription factor 3b, putative 0.0025 0.0011 0.0011
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0059 0.0045 0.0815
Trypanosoma cruzi DNA polymerase eta, putative 0.0116 0.0101 0.0134
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0003 0.0003
Schistosoma mansoni single-minded 0.024 0.0224 0.0224
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0006 0.0006
Schistosoma mansoni neuropeptide receptor 0.0017 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0003 0.0003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Echinococcus multilocularis neuropeptide s receptor 0.0287 0.0271 0.0271
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0147 0.0132 0.0132
Brugia malayi MH2 domain containing protein 0.0032 0.0018 0.0018
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0062 0.0048 0.102
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0057 0.0042 0.1405
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.002 0.0006 0.0097
Schistosoma mansoni thyroid hormone receptor 0.0147 0.0132 0.0132
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0017 0.0003 0.0045
Brugia malayi GnHR receptor homolog 0.0017 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0072 0.0057 0.0075
Plasmodium falciparum DNA topoisomerase 3, putative 0.025 0.0234 0.0234
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0017 0.0003 0.0067
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0072 0.0057 0.0077
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0004
Schistosoma mansoni acetyl-CoA synthetase 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni tyrosine kinase 0.0181 0.0165 0.0165
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Toxoplasma gondii melibiase subfamily protein 0.0107 0.0092 0.0092
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Brugia malayi Cytochrome P450 family protein 0.0047 0.0032 0.0032
Trypanosoma brucei unspecified product 0.005 0.0036 0.0048
Entamoeba histolytica DNA (cytosine-5)-methyltransferase, putative 0.0019 0.0005 0.0174
Loa Loa (eye worm) hypothetical protein 0.0804 0.0785 0.0785
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0113 0.0098 0.0098
Entamoeba histolytica Ran family GTPase 0.0053 0.0039 0.1366
Schistosoma mansoni smad 0.0032 0.0018 0.0018
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0003 0.0003
Plasmodium vivax steroid dehydrogenase, putative 0.0016 0.0001 0.0001
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0475 0.0458 0.0458
Schistosoma mansoni zinc finger protein 0.0069 0.0055 0.0055
Trichomonas vaginalis DNA polymerase eta, putative 0.0099 0.0084 0.1799
Giardia lamblia Flap structure-specific endonuclease 0.0027 0.0012 0.0434
Echinococcus multilocularis FTZ F1 alpha 0.0147 0.0132 0.0132
Trypanosoma brucei PAB1-binding protein , putative 0.0102 0.0087 0.0118
Brugia malayi ORL1-like opioid receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Leishmania major cathepsin L-like protease 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0001 0.0012
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0046 0.0031 0.1106
Brugia malayi jmjC domain containing protein 0.0128 0.0113 0.0113
Schistosoma mansoni nuclear hormone receptor 0.0147 0.0132 0.0132
Echinococcus multilocularis neuropeptide receptor A26 0.0287 0.0271 0.0271
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Echinococcus granulosus lamin 0.0054 0.004 0.004
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.0102 0.0087 0.0087
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0016 0.0001 0.0012
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0051 0.0067
Loa Loa (eye worm) fibroinase 0.002 0.0006 0.0006
Plasmodium vivax DNA repair protein REV1, putative 0.0023 0.0008 0.0008
Brugia malayi intermediate filament protein 0.0054 0.004 0.004
Onchocerca volvulus 0.0478 0.0461 0.9845
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0124 0.0109 0.0145
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0025 0.0011 0.0228
Onchocerca volvulus 0.0017 0.0003 0.0067
Onchocerca volvulus 0.0021 0.0007 0.0143
Loa Loa (eye worm) oxidoreductase 0.0017 0.0003 0.0003
Echinococcus multilocularis multidrug and toxin extrusion protein 2 0.0066 0.0052 0.0052
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0037 0.0023 0.0023
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0017 0.0003 0.0033
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma brucei metacaspase MCA2 0.0088 0.0073 0.0098
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0057 0.0042 0.1483
Trypanosoma brucei DNA topoisomerase III, putative 0.013 0.0115 0.0155
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0047 0.0032 0.1147
Echinococcus multilocularis 0.0401 0.0384 0.0384
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0014 0.0291
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0087 0.0073 0.0096
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0017 0.0003 0.0033
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0009
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0192 0.0177 0.0177
Mycobacterium tuberculosis Conserved protein 0.0021 0.0007 0.0115
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0088 0.0073 0.0073
Trichomonas vaginalis guanylate cyclase, putative 0.0062 0.0048 0.102
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0059 0.0045 0.0815
Echinococcus granulosus Niemann Pick C1 protein 0.006 0.0045 0.0045
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0016 0.0001 0.0029
Loa Loa (eye worm) ICD-1 protein 0.0025 0.0011 0.0011
Entamoeba histolytica short chain dehydrogenase family protein 0.0016 0.0001 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.002 0.0006 0.0097
Brugia malayi nuclear receptor NHR-67 0.0069 0.0055 0.0055
Echinococcus granulosus sex peptide receptor 0.0017 0.0003 0.0003
Echinococcus granulosus tumor protein p63 0.0352 0.0336 0.0336
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.0253 0.541
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.002 0.0006 0.0085
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0427 0.041 0.041
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0001 0.0001
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0027 0.0012 0.0012
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0027 0.0012 0.0016
Brugia malayi dehydrogenases, short chain protein 9 0.0016 0.0001 0.0001
Schistosoma mansoni ADAM17 peptidase (M12 family) 0.0223 0.0207 0.0207
Echinococcus multilocularis kelch ECH associated protein 1 0.0091 0.0077 0.0077
Onchocerca volvulus 0.0069 0.0055 0.1163
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.0007 0.0007
Leishmania major 4-coumarate:coa ligase-like protein 0.0059 0.0045 0.0058
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0017 0.0003 0.0033
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.002 0.0006 0.0121
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0003 0.0003
Trypanosoma cruzi DNA topoisomerase IB, large subunit, putative 0.7471 0.7411 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0084 0.0112
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0003 0.0045
Leishmania major cathepsin L-like protease 0.002 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0013 0.0286
Echinococcus multilocularis ATP binding cassette sub family G 0.0019 0.0005 0.0005
Echinococcus multilocularis cpg binding protein 0.0195 0.018 0.018
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0215 0.02 0.0268
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0192 0.0177 0.0237
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0048 0.0048
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.0007 0.0007
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.002 0.0006 0.0085
Entamoeba histolytica hypothetical protein 0.0058 0.0044 0.1556
Schistosoma mansoni inositol monophosphatase 0.0113 0.0098 0.0098
Echinococcus multilocularis lysine specific demethylase 6a 0.0032 0.0017 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi SET domain containing protein 0.0019 0.0004 0.0004
Echinococcus granulosus hypothetical protein 0.0737 0.0718 0.0718
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0012 0.0012
Echinococcus multilocularis jumonji domain containing 1A 0.0032 0.0017 0.0017
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0057 0.0057
Trichomonas vaginalis rotamase, putative 0.0053 0.0038 0.0817
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0231 0.0216 0.0216
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0077 0.0063 0.0063
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0051 0.0051
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.0282 1
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0048 0.0034 0.0044
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0241 0.0225 0.0225
Brugia malayi Cytochrome P450 family protein 0.002 0.0006 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0063 0.0048 0.0048
Brugia malayi CXXC zinc finger family protein 0.0186 0.0171 0.0171
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0051 0.0069
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0032 0.0017 0.0017
Echinococcus multilocularis jun protein 0.0081 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0078 0.0064 0.0064
Schistosoma mansoni jumonji/arid domain-containing protein 0.0128 0.0113 0.0113
Echinococcus granulosus sentrin specific protease 1 0.0025 0.0011 0.0011
Onchocerca volvulus 0.0017 0.0003 0.0061
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni kinase 0.0096 0.0081 0.0081
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0006 0.0006
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0016 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0006 0.0121
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0003 0.0003
Brugia malayi hypoxia-induced factor 1 0.0742 0.0723 0.0723
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0002 0.0001
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0047 0.0032 0.0044
Loa Loa (eye worm) hypothetical protein 0.0032 0.0017 0.0017
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0079 0.1683
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0017 0.0003 0.0002
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0057 0.0042 0.0896
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0012
Brugia malayi ATPase, AAA family protein 0.0014 0.00000014189 0.00000014189
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0048 0.0034 0.0725
Brugia malayi Glycosyl hydrolases family 31 protein 0.0048 0.0034 0.0034
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0147 0.0132 0.0132
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0003 0.0003
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0057 0.0042 0.0055
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0017 0.0003 0.0002
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.002 0.0006 0.0097
Brugia malayi Nuclear hormone receptor E75 0.0069 0.0055 0.0055
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0016 0.0001 0.0001
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0192 0.0177 0.0177
Onchocerca volvulus 0.0017 0.0003 0.0067
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0057 0.0042 0.0042
Trypanosoma cruzi cytochrome p450-like protein, putative 0.002 0.0006 0.0006
Brugia malayi ABC transporter family protein 0.0016 0.0002 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Loa Loa (eye worm) reprolysin 0.0022 0.0008 0.0008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0147 0.0132 0.0132
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0582 0.0564 0.0564
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0071 0.0057 0.0057
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0063 0.0048 0.0048
Trichomonas vaginalis guanylate cyclase, putative 0.0062 0.0048 0.102
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0006 0.0006
Schistosoma mansoni terminal deoxycytidyl transferase 0.0073 0.0058 0.0058
Onchocerca volvulus 0.0178 0.0163 0.347
Brugia malayi ecdysone receptor 0.0069 0.0055 0.0055
Trichomonas vaginalis steroid dehydrogenase, putative 0.0016 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.0109 0.2025
Onchocerca volvulus Netrin receptor homolog 0.0015 0.0001 0.0013
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0003 0.0003
Leishmania major DNA topoisomerase IB, large subunit 0.7471 0.7411 1
Brugia malayi Serotonin receptor 0.0017 0.0003 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0092 0.0092
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0003 0.0003
Echinococcus granulosus dnaJ subfamily B 0.177 0.1745 0.1745
Loa Loa (eye worm) nuclear factor I 0.0018 0.0004 0.0004
Trypanosoma brucei DNA polymerase IV, putative 0.0099 0.0084 0.0114
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0115 0.2461
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0017 0.0003 0.0003
Trichomonas vaginalis ran, putative 0.0053 0.0039 0.0824
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0005 0.0007
Plasmodium vivax DNA topoisomerase 3, putative 0.025 0.0234 0.0234
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0027 0.0012 0.0017
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Echinococcus multilocularis ferritin 0.0026 0.0011 0.0011
Brugia malayi Matrixin family protein 0.0085 0.007 0.007
Leishmania major hypothetical protein, conserved 0.0066 0.0052 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Schistosoma mansoni dihydroceramide desaturase 0.0022 0.0008 0.0008
Trichomonas vaginalis D-aminoacylase, putative 0.0021 0.0007 0.0146
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0382
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0019 0.0005 0.007
Leishmania major adenylate cyclase-like protein 0.0026 0.0011 0.0013
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.002 0.0006 0.0097
Leishmania major protein kinase, putative 0.0064 0.0049 0.0065
Plasmodium falciparum JmjC domain-containing protein, putative 0.0032 0.0017 0.0017
Echinococcus multilocularis caspase 0.0231 0.0216 0.0216
Brugia malayi Importin beta-1 subunit 0.0072 0.0057 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0115 0.0154
Schistosoma mansoni DNA (cytosine-5)-methyltransferase 0.0019 0.0005 0.0005
Mycobacterium ulcerans bacterioferritin BfrB 0.0026 0.0011 0.0189
Schistosoma mansoni hypothetical protein 0.077 0.0751 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0121
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0003 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Echinococcus granulosus Nuclear hormone receptor HR96 0.0069 0.0055 0.0055
Brugia malayi G protein-coupled receptor 0.0017 0.0003 0.0003
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0107 0.0092 0.0092
Schistosoma mansoni myoglobin 1 0.0026 0.0011 0.0011
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.0011 0.023
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0073 0.1555
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0015 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Loa Loa (eye worm) oxidoreductase 0.0016 0.0001 0.0001
Mycobacterium leprae conserved hypothetical protein 0.0021 0.0007 0.0103
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0003 0.0003
Brugia malayi Matrixin family protein 0.0085 0.007 0.007
Echinococcus granulosus hypothetical protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0016 0.0001 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0115 0.2461
Trypanosoma brucei importin beta-1 subunit, putative 0.0072 0.0057 0.0078
Plasmodium falciparum histone acetyltransferase GCN5 0.0157 0.0142 0.0142
Brugia malayi Serotonin receptor 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0112 0.0097 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Trypanosoma brucei unspecified product 0.005 0.0036 0.0048
Echinococcus multilocularis Protein lozenge 0.004 0.0025 0.0025
Toxoplasma gondii hypothetical protein 0.0082 0.0068 0.0068
Echinococcus multilocularis DNA methyltransferase 2, putative 0.0019 0.0005 0.0005
Brugia malayi hypothetical protein 0.0804 0.0785 0.0785
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Schistosoma mansoni cpg binding protein 0.0186 0.0171 0.0171
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0167 0.0152 0.0152
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0167 0.0152 0.0152
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0032 0.0017 0.0022
Schistosoma mansoni nuclear receptor 0.0069 0.0055 0.0055
Echinococcus granulosus geminin 0.0911 0.0891 0.0891
Mycobacterium ulcerans acyl-CoA synthetase 0.0059 0.0045 0.0815
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0053 0.0039 0.0039
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0077 0.0063 0.0063
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0269 0.0253 0.0253
Trypanosoma brucei hypothetical protein, conserved 0.0021 0.0007 0.0009
Entamoeba histolytica acyl-CoA synthetase, putative 0.0059 0.0045 0.1582
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0017 0.0003 0.0003
Echinococcus granulosus citrate lyase subunit beta protein 0.0025 0.001 0.001
Leishmania major alpha glucosidase II subunit, putative 0.013 0.0115 0.0154
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0003 0.0003
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0032 0.0018 0.0018
Entamoeba histolytica acyl-CoA synthetase, putative 0.0059 0.0045 0.1582
Onchocerca volvulus 0.013 0.0115 0.2454
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0044 0.003 0.0535
Schistosoma mansoni caspase-7 (C14 family) 0.0199 0.0184 0.0184
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0227
Toxoplasma gondii DNA methyltransferase 2, putative 0.0019 0.0005 0.0005
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.002 0.0006 0.0085
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0003 0.0003
Brugia malayi polk-prov protein 0.0049 0.0034 0.0034
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0047 0.0032 0.0042
Chlamydia trachomatis DNA gyrase subunit B 0.0057 0.0042 0.1438
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Echinococcus granulosus somatostatin receptor 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0016 0.0001 0.0002
Leishmania major glycosyl hydrolase-like protein 0.0048 0.0034 0.0044
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0001 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0002 0.004
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.002 0.0006 0.0085
Plasmodium falciparum thioredoxin reductase 0.0049 0.0035 0.0035
Leishmania major DNA damage repair protein, putative 0.0023 0.0008 0.0009
Echinococcus granulosus WW domain containing oxidoreductase 0.0016 0.0001 0.0001
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Plasmodium vivax vivapain-2 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0071 0.0057 0.0057
Trypanosoma brucei unspecified product 0.0092 0.0078 0.0105
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0021 0.0007 0.0007
Loa Loa (eye worm) DNA topoisomerase III beta-1 0.013 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0085 0.007 0.007
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0077 0.0063 0.0063
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.002 0.0006 0.0085
Echinococcus multilocularis Smad4 0.0032 0.0018 0.0018
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0031
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0001 0.0001
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0069 0.0055 0.1163
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0064 0.005 0.005
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0107 0.0092 0.0092
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0113 0.0098 0.1813
Brugia malayi Dopamine receptor 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.002 0.0006 0.0006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis microtubule associated protein 2 0.3028 0.2995 0.2995
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Mycobacterium tuberculosis Probable lipase LipE 0.0021 0.0007 0.0115
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0016 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0233
Echinococcus granulosus ATP binding cassette sub family G 0.0019 0.0005 0.0005
Toxoplasma gondii Alpha-galactosidase 0.0015 0.0001 0.0001
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.004 0.0026 0.0026
Onchocerca volvulus 0.0017 0.0003 0.0067
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0017 0.0003 0.0064
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0051 0.0051
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0147 0.0132 0.0132
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0015 0.0001 0.0001
Brugia malayi isocitrate dehydrogenase 0.0063 0.0048 0.0048
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.051 0.0492 0.0662
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.013 0.0115 0.4081
Echinococcus multilocularis a disintegrin and metalloproteinase with 0.0105 0.009 0.009
Echinococcus granulosus survival motor neuron protein 1 0.1181 0.116 0.116
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Mycobacterium ulcerans aldehyde dehydrogenase 0.0192 0.0177 0.3303
Mycobacterium leprae Probable lipase LipE 0.0021 0.0007 0.0103
Entamoeba histolytica ABC transporter, putative 0.0019 0.0005 0.018
Trichomonas vaginalis antibiotic synthetase, putative 0.0017 0.0003 0.0066
Echinococcus granulosus transcription factor eb 0.0077 0.0062 0.0062
Echinococcus multilocularis snurportin 1 0.077 0.0751 0.0751
Echinococcus granulosus ecdysone induced protein 78C 0.0147 0.0132 0.0132
Echinococcus granulosus nuclear factor of activated T cells 5 0.0077 0.0062 0.0062
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0063 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0003 0.0003
Toxoplasma gondii carbonyl reductase 1, putative 0.0016 0.0001 0.0001
Plasmodium falciparum DNA (cytosine-5)-methyltransferase 0.0019 0.0005 0.0005
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0032 0.0018 0.0018
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0001 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0003 0.0003
Trypanosoma brucei ATP-binding cassette protein, putative 0.0019 0.0005 0.0007
Trypanosoma brucei glycosyl hydrolase-like protein 0.0048 0.0034 0.0046
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0003 0.0003
Echinococcus multilocularis netrin receptor unc 5 0.0015 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0006 0.0121
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.002 0.0006 0.0097
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0017 0.0003 0.0045
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0008 0.0011
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0069 0.0055 0.0055
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0041 0.0026 0.0026
Mycobacterium ulcerans acetyl-CoA synthetase 0.0017 0.0003 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.005 0.0035 0.0035
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0016 0.0001 0.0012
Mycobacterium tuberculosis Conserved protein 0.0021 0.0007 0.0115
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0032 0.0017 0.0017
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0003 0.006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0003 0.0003
Echinococcus granulosus neutral alpha glucosidase AB 0.013 0.0115 0.0115
Echinococcus multilocularis kelch ECH associated protein 1 0.0091 0.0077 0.0077
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0081 0.0066 0.0066
Onchocerca volvulus 0.002 0.0006 0.0119
Schistosoma mansoni neuropeptide receptor 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.002 0.0006 0.0097
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0017 0.0003 0.011
Echinococcus granulosus FTZ F1 alpha 0.0147 0.0132 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0227
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0131 0.2434
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.0011 0.023
Trichomonas vaginalis penicillin-binding protein, putative 0.0021 0.0007 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0059 0.0045 0.0815
Echinococcus multilocularis transcription factor eb 0.0077 0.0062 0.0062
Echinococcus multilocularis aryl hydrocarbon receptor 0.0063 0.0048 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0016 0.0002 0.004
Mycobacterium ulcerans esterase/lipase LipP 0.0021 0.0007 0.0103
Trypanosoma cruzi DNA polymerase eta, putative 0.0066 0.0051 0.0067
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0027 0.0012 0.0216
Brugia malayi angiogenesis inhibito 0.0017 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Brugia malayi Glycosyl hydrolases family 31 protein 0.0529 0.0511 0.0511
Echinococcus granulosus expressed protein 0.0053 0.0038 0.0038
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0308 0.0292 0.0292
Plasmodium falciparum zinc finger protein, putative 0.0018 0.0004 0.0004
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.004 0.0026 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0034 0.0727
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0017 0.0003 0.0003
Leishmania major cytochrome p450-like protein 0.0047 0.0032 0.0042
Plasmodium vivax DNA topoisomerase II, putative 0.0057 0.0042 0.0042
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0077 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Brugia malayi Dopamine receptor protein 1 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Echinococcus granulosus adam 17 protease 0.0245 0.0229 0.0229
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0069 0.0055 0.0055
Trypanosoma cruzi DNA topoisomerase IA, putative 0.025 0.0234 0.0314
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0529 0.0511 0.0511
Echinococcus granulosus expressed conserved protein 0.0056 0.0042 0.0042
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0041 0.0026 0.0026
Toxoplasma gondii NAC domain-containing protein 0.0025 0.0011 0.0011
Brugia malayi CHE-14 protein 0.0026 0.0011 0.0011
Loa Loa (eye worm) cytochrome P450 family protein 0.0047 0.0032 0.0032
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.0253 0.541
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0062 0.0048 0.102
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0017 0.0003 0.0061
Echinococcus granulosus serotonin receptor 0.0017 0.0003 0.0003
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0164 0.0149 0.5274
Trypanosoma cruzi metacaspase, putative 0.0088 0.0073 0.0096
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0016 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Mycobacterium ulcerans DNA polymerase IV 0.0099 0.0084 0.1559
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0072 0.0057 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.0061 0.0081
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0147 0.0132 0.0132
Brugia malayi orphan nuclear receptor NR2E1 0.0069 0.0055 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0017 0.0017
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.0282 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0008 0.0009
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0003 0.0003
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0031 0.0031
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.055 0.0533 1
Trichomonas vaginalis CAMK family protein kinase 0.0094 0.0079 0.1683
Loa Loa (eye worm) hypothetical protein 0.0112 0.0097 0.0097
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0003 0.0003
Brugia malayi RNA, U transporter 1 0.0205 0.019 0.019
Echinococcus granulosus jun protein 0.0081 0.0066 0.0066
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Brugia malayi Matrixin family protein 0.0205 0.0189 0.0189
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0064 0.0049 0.0065
Plasmodium vivax acyl-CoA synthetase, putative 0.0044 0.003 0.003
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0858 0.0839 0.0839
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.0016 0.0002 0.0015
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.0058 0.0058
Plasmodium falciparum importin beta, putative 0.0072 0.0057 0.0057
Plasmodium falciparum glutathione reductase 0.0049 0.0035 0.0035
Schistosoma mansoni hypothetical protein 0.0241 0.0225 0.0225
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0088 0.0073 0.0073
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.002 0.0006 0.0097
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0016 0.0001 0.0029
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0064 0.0049 0.0065
Loa Loa (eye worm) hypothetical protein 0.0019 0.0004 0.0004
Echinococcus multilocularis conserved hypothetical protein 0.0719 0.0701 0.0701
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Brugia malayi AMP-binding enzyme family protein 0.0059 0.0045 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.0064 0.005 0.005
Schistosoma mansoni biogenic amine receptor 0.0017 0.0003 0.0003
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0017 0.0003 0.0003
Echinococcus granulosus sentrin specific protease 7 0.0025 0.0011 0.0011
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0234
Loa Loa (eye worm) hypothetical protein 0.0054 0.004 0.004
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi nuclear receptor RXR 0.0077 0.0063 0.0063
Echinococcus granulosus DNA topoisomerase 3 alpha 0.0257 0.0241 0.0241
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0027 0.0012 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Brugia malayi Matrixin family protein 0.0085 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0023 0.0009 0.0009
Onchocerca volvulus 0.0026 0.0011 0.0239
Mycobacterium ulcerans DNA gyrase subunit B 0.0057 0.0042 0.0766
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0052 0.0068
Leishmania major metacaspase, putative 0.0088 0.0073 0.0096
Brugia malayi serine/threonine-protein kinase plk-2 0.0188 0.0173 0.0173
Trypanosoma cruzi importin beta-1 subunit, putative 0.0058 0.0044 0.0057
Brugia malayi follicle stimulating hormone receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0052 0.0052
Brugia malayi Protein kinase domain containing protein 0.0176 0.016 0.016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.0192 0.0177 0.0177
Loa Loa (eye worm) hypothetical protein 0.0375 0.0359 0.0359
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.004 0.004
Leishmania major lanosterol 14-alpha-demethylase, putative 0.002 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi RE15519p 0.0017 0.0003 0.0003
Echinococcus granulosus regulator of G protein signaling 7 0.0037 0.0023 0.0023
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0069 0.0055 0.1163
Echinococcus multilocularis DNA topoisomerase 1 1.0077 1 1
Loa Loa (eye worm) ABC transporter 0.0016 0.0002 0.0002
Echinococcus granulosus dna polymerase eta 0.0116 0.0101 0.0101
Echinococcus granulosus mixed lineage leukemia protein mll 0.004 0.0026 0.0026
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0052 0.0037 0.0037
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0027 0.0012 0.0015
Giardia lamblia DNA topoisomerase III 0.025 0.0234 0.8279
Mycobacterium ulcerans citrate lyase beta subunit, CitE_2 0.0025 0.001 0.0172
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0037 0.0023 0.0023
Schistosoma mansoni aryl hydrocarbon receptor 0.024 0.0225 0.0225
Giardia lamblia Sentrin specific protease, putative 0.0025 0.0011 0.0382
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0012 0.0012
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0308 0.0292 0.0292
Schistosoma mansoni opsin-like receptor 0.0017 0.0003 0.0003
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0113 0.0098 0.351
Mycobacterium ulcerans hypothetical protein 0.0059 0.0045 0.0815
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0125 0.011 0.2055
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.035 0.0334 0.7124
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus granulosus cathepsin L cysteine proteinase 0.002 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0084 0.0112
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0006 0.0006
Schistosoma mansoni rotamase 0.0053 0.0038 0.0038
Onchocerca volvulus 0.002 0.0006 0.0119
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0006 0.0006
Echinococcus granulosus beta LACTamase domain containing family member 0.0021 0.0007 0.0007
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0057 0.0042 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0034 0.0727
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.002 0.0006 0.0097
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0012
Loa Loa (eye worm) hypothetical protein 0.0316 0.03 0.03
Echinococcus granulosus a disintegrin and metalloproteinase with 0.0105 0.009 0.009
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0032 0.0017 0.0017
Brugia malayi jmjC domain containing protein 0.0032 0.0017 0.0017
Onchocerca volvulus Huntingtin homolog 0.0375 0.0359 0.7657
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Onchocerca volvulus Cell death protein 3 homolog 0.0199 0.0184 0.3921
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0021 0.0007 0.0115
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0048 0.0063
Onchocerca volvulus 0.0017 0.0003 0.0067
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0001 0.0048
Echinococcus granulosus disco interacting protein 2 0.004 0.0025 0.0025
Brugia malayi beta-lactamase 0.0021 0.0007 0.0007
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.013 0.0115 0.0115
Echinococcus multilocularis JmjC domain containing protein 4 0.0032 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.012 0.0105 0.0105
Loa Loa (eye worm) hypothetical protein 0.0044 0.003 0.003
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0003 0.0003
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0037 0.0023 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.0253 0.541
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0016 0.0001 0.0001
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0003 0.0003
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0017 0.0003 0.0033
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0023 0.0488
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0032 0.0692
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0098 0.013
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0037 0.0023 0.0029
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Echinococcus granulosus dna polymerase kappa 0.0099 0.0084 0.0084
Brugia malayi Melatonin receptor type 1A 0.0017 0.0003 0.0003
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0063 0.0048 0.0048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0048 0.0063
Leishmania major importin beta-1 subunit, putative 0.0058 0.0044 0.0057
Echinococcus multilocularis expressed protein 0.0389 0.0372 0.0372
Trypanosoma brucei chrX additional, unordered contigs 0.0023 0.0008 0.0011
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0167 0.0152 0.0152
Echinococcus granulosus mothers against decapentaplegic 5 0.0032 0.0018 0.0018
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0001 0.0001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0003 0.0052
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.002 0.0006 0.0085
Echinococcus multilocularis serotonin receptor 0.0017 0.0003 0.0003
Trypanosoma brucei trypanothione reductase 0.0049 0.0035 0.0047
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0017 0.0003 0.0045
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0042 0.0057
Plasmodium vivax topoisomerase I, putative 1.0077 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0017 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0003 0.0003
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0019 0.0005 0.0005
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0001 0.0027
Loa Loa (eye worm) DR-78 0.0069 0.0055 0.0055
Onchocerca volvulus 0.0016 0.0001 0.0027
Leishmania major DNA polymerase kappa, putative 0.0023 0.0008 0.0009
Schistosoma mansoni bromodomain containing protein 0.0023 0.0009 0.0009
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0017 0.0003 0.0045
Loa Loa (eye worm) nuclear receptor NHR-67 0.0069 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0023 0.0488
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0021 0.0007 0.0115
Brugia malayi Ets-domain containing protein 0.0078 0.0064 0.0064
Schistosoma mansoni cytochrome P450 0.002 0.0006 0.0006
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0006
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Loa Loa (eye worm) glutathione reductase 0.0049 0.0035 0.0035
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0013 0.0286
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0116 0.0101 0.0101
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0052 0.0068
Brugia malayi photoreceptor-specific nuclear receptor 0.0858 0.0839 0.0839
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0012
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0171 0.3648
Brugia malayi hypothetical protein 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0069 0.0055 0.0055
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0216 0.02 0.02
Brugia malayi Dopamine receptor protein 2 0.0017 0.0003 0.0003
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0019 0.0005 0.0005
Echinococcus multilocularis protein tyrosine kinase 0.0181 0.0165 0.0165
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0171 0.0156 0.0156
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Plasmodium vivax ABC transporter G family member 2, putative 0.0019 0.0005 0.0005
Trichomonas vaginalis alpha-glucosidase, putative 0.013 0.0115 0.2461
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0223 0.0208 0.0208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Plasmodium vivax metacaspase 1, putative 0.0088 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.002 0.0006 0.0201
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0006 0.0006
Brugia malayi Disintegrin family protein 0.0022 0.0008 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.013 0.0115 0.0154
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0001 0.0002
Entamoeba histolytica bromodomain-containing protein 0.0014 0.000000033674 0.0000010725
Echinococcus granulosus kelch ECH associated protein 1 like 0.0091 0.0077 0.0077
Loa Loa (eye worm) jmjC domain-containing protein 0.0128 0.0113 0.0113
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0067 0.0053 0.0053
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0073 0.0058 0.0058
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.0087 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0052 0.0068
Echinococcus granulosus multidrug and toxin extrusion protein 2 0.0066 0.0052 0.0052
Schistosoma mansoni phd/f-box containing protein 0.0032 0.0017 0.0017
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0077 0.0062 0.0062
Brugia malayi hypothetical protein 0.0067 0.0053 0.0053
Brugia malayi exodeoxyribonuclease III family protein 0.0027 0.0012 0.0012
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0382
Trypanosoma brucei glucosidase, putative 0.013 0.0115 0.0156
Mycobacterium tuberculosis Probable reductase 0.0112 0.0098 0.182
Schistosoma mansoni disco-interacting protein 2 (dip2) 0.004 0.0025 0.0025
Leishmania major cysteine peptidase A (CPA) 0.002 0.0006 0.0006
Trypanosoma brucei DNA polymerase eta, putative 0.0116 0.0101 0.0136
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.002 0.0006 0.0085
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0003 0.0027
Loa Loa (eye worm) RNA binding protein 0.0109 0.0094 0.0094
Entamoeba histolytica acyl-coA synthetase, putative 0.0059 0.0045 0.1582
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Schistosoma mansoni alpha glucosidase 0.013 0.0115 0.0115
Brugia malayi AKH receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) globin family protein 0.0026 0.0011 0.0011
Brugia malayi Helix-loop-helix DNA-binding domain containing protein 0.0077 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Schistosoma mansoni subfamily M12B unassigned peptidase (M12 family) 0.0022 0.0008 0.0008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0147 0.0132 0.0132
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0077 0.0063 0.0063
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0269 0.0253 0.0253
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Entamoeba histolytica hypothetical protein 0.0025 0.0011 0.0377
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0061 0.0081
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0017 0.0003 0.0003
Treponema pallidum exodeoxyribonuclease (exoA) 0.0027 0.0012 0.0335
Onchocerca volvulus 0.0017 0.0003 0.0064
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0057 0.0042 0.0042
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.0007 0.0007
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis sentrin specific protease 1 0.0025 0.0011 0.0011
Echinococcus granulosus histone acetyltransferase KAT2B 0.0566 0.0548 0.0548
Echinococcus granulosus allatostatin A receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0014 0.0291
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0057 0.0042 0.0896
Schistosoma mansoni ferritin light chain 0.0026 0.0011 0.0011
Brugia malayi PXA domain containing protein 0.002 0.0006 0.0006
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0047 0.0032 0.0032
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0003 0.0003
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Loa Loa (eye worm) inositol-1 0.0113 0.0098 0.0098
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0098 0.013
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0003 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0059 0.0045 0.0058
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0063 0.0048 0.0048
Schistosoma mansoni amine GPCR 0.0017 0.0003 0.0003
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0147 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0032 0.0017 0.0017
Schistosoma mansoni lamin 0.0054 0.004 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0079 0.0064 0.0064
Plasmodium falciparum metacaspase-like protein 0.0088 0.0073 0.0073
Brugia malayi AMP-binding enzyme family protein 0.0059 0.0045 0.0045
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Trypanosoma cruzi DNA topoisomerase type IB small subunit, putative 0.4044 0.4005 0.5403
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0006
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.002 0.0006 0.0097
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0053 0.0039 0.1366
Brugia malayi PXA domain containing protein 0.002 0.0006 0.0006
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0001 0.0001
Brugia malayi Matrixin family protein 0.0085 0.007 0.007
Loa Loa (eye worm) TK/FAK protein kinase 0.0183 0.0167 0.0167
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0027 0.0502
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0052 0.0037 0.1311
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0016 0.0001 0.0048
Loa Loa (eye worm) helix-loop-helix DNA-binding domain-containing protein 0.0077 0.0062 0.0062
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.002 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0037 0.0037
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Onchocerca volvulus Huntingtin homolog 0.0375 0.0359 0.7657
Onchocerca volvulus 0.0017 0.0003 0.0067
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0017 0.0003 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Loa Loa (eye worm) hypothetical protein 0.0059 0.0045 0.0045
Onchocerca volvulus 0.002 0.0006 0.0119
Brugia malayi G-protein coupled receptor 0.0017 0.0003 0.0003
Toxoplasma gondii LsmAD domain-containing protein 0.0102 0.0087 0.0087
Echinococcus multilocularis polybromo 1 0.0019 0.0004 0.0004
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0016 0.0002 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0023 0.0493
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0003 0.0003
Echinococcus granulosus smad 0.0032 0.0018 0.0018
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0069 0.0055 0.0055
Entamoeba histolytica hypothetical protein 0.002 0.0006 0.0201
Schistosoma mansoni thyroid hormone receptor 0.0147 0.0132 0.0132
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0023 0.0488
Onchocerca volvulus 0.0016 0.0001 0.0027
Brugia malayi putative neuropeptide receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis protein kinase inhibitor, putative 0.0105 0.009 0.1924
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0003 0.0003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0003 0.0002
Onchocerca volvulus 0.0017 0.0003 0.0067
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.013 0.0115 0.2461
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Schistosoma mansoni steroid hormone receptor ad4bp 0.0147 0.0132 0.0132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0147 0.0132 0.0132
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Echinococcus multilocularis tumor protein p63 0.0352 0.0336 0.0336
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0021 0.0007 0.0007
Entamoeba histolytica protein kinase domain containing protein 0.0104 0.0089 0.3146
Loa Loa (eye worm) hypothetical protein 0.0022 0.0008 0.0008
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0098 0.182
Onchocerca volvulus 0.0147 0.0132 0.2807
Entamoeba histolytica hypothetical protein 0.0016 0.0001 0.0048
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0016 0.0001 0.0012
Echinococcus granulosus caspase 2 0.0199 0.0184 0.0184
Entamoeba histolytica DNA topoisomerase III, putative 0.025 0.0234 0.8279
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Brugia malayi Protein kinase domain containing protein 0.0183 0.0167 0.0167
Plasmodium vivax acetyl-CoA synthetase, putative 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0016 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0102 0.0087 0.0116
Echinococcus granulosus g protein coupled receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis transient receptor potential cation channel 0.0016 0.0001 0.0001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0167 0.0152 0.0152
Entamoeba histolytica DNA topoisomerase II, putative 0.0057 0.0042 0.149
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Plasmodium vivax sentrin-specific protease 2, putative 0.0025 0.0011 0.0011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0129 0.0114 0.0114
Mycobacterium tuberculosis Probable monooxygenase 0.0026 0.0011 0.0199
Schistosoma mansoni ADAMTS5 peptidase (M12 family) 0.0105 0.009 0.009
Brugia malayi Retinol dehydrogenase 12 0.0016 0.0001 0.0001
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0062 0.0048 0.1647
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.055 0.0533 1
Echinococcus granulosus aryl hydrocarbon receptor 0.0063 0.0048 0.0048
Trichomonas vaginalis DNA topoisomerase II, putative 0.0057 0.0042 0.0899
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.002 0.0437
Trichomonas vaginalis importin beta-1, putative 0.0058 0.0044 0.0938
Loa Loa (eye worm) CXXC zinc finger family protein 0.0186 0.0171 0.0171
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0003 0.0003
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0066 0.0051 0.0051
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0027 0.0012 0.0012
Plasmodium falciparum sentrin-specific protease 1 0.0025 0.0011 0.0011
Brugia malayi F/Y-rich N-terminus family protein 0.0049 0.0035 0.0035
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0016 0.0002 0.0001
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0008 0.0009
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0006 0.0006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Brugia malayi AMP-binding enzyme family protein 0.0059 0.0045 0.0045
Plasmodium vivax flap endonuclease 1, putative 0.0027 0.0012 0.0012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0041 0.0026 0.0026
Onchocerca volvulus 0.0021 0.0007 0.0143
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium leprae Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( 0.025 0.0234 0.4374
Giardia lamblia DNA topoisomerase III 0.013 0.0115 0.4073
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0077 0.0063 0.1335
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.0016 0.0001 0.0001
Toxoplasma gondii exonuclease III APE 0.0027 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0124 0.0109 0.2025
Loa Loa (eye worm) hypothetical protein 0.0059 0.0045 0.0045
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0104 0.0089 0.012
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.004 0.0026 0.0026
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0064 0.005 0.005
Leishmania major DNA polymerase eta, putative 0.0116 0.0101 0.0134
Schistosoma mansoni adam (A disintegrin and metalloprotease 0.0039 0.0024 0.0024
Onchocerca volvulus 0.0052 0.0037 0.0789
Echinococcus multilocularis sentrin specific protease 7 0.0025 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Echinococcus granulosus Protein patched homolog 1 0.0026 0.0011 0.0011
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.0073 0.0059 0.1255
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0014 0 0.0002
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Toxoplasma gondii propionate-CoA ligase 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0382
Schistosoma mansoni DNA topoisomerase type I 1.0077 1 1
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0026 0.0011 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0031
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0582 0.0564 0.0564
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni myosin xvIII 0.0017 0.0003 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.0087 0.0116
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0062 0.0048 0.102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0003 0.0003
Loa Loa (eye worm) steroid hormone receptor 0.0147 0.0132 0.0132
Echinococcus granulosus expressed protein 0.0389 0.0372 0.0372
Echinococcus granulosus g protein coupled receptor 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor-like 1 0.0147 0.0132 0.0132
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0029 0.0015 0.0015
Onchocerca volvulus 0.0281 0.0265 0.5661
Trichomonas vaginalis hypothetical protein 0.0019 0.0004 0.0094
Schistosoma mansoni ets-related 0.0237 0.0222 0.0222
Brugia malayi hypothetical protein 0.0216 0.02 0.02
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0016 0.0001 0.0002
Plasmodium falciparum DNA topoisomerase 2 0.0057 0.0042 0.0042
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Mycobacterium leprae putative cytochrome p450 0.002 0.0006 0.0085
Plasmodium vivax importin-beta 2, putative 0.0072 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0059 0.0045 0.0045
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0003 0.0003
Schistosoma mansoni carbonyl reductase 0.0016 0.0001 0.0001
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0047 0.0032 0.058
Echinococcus granulosus Niemann Pick C1 protein 0.0085 0.0071 0.0071
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.0011 0.023
Schistosoma mansoni hypothetical protein 0.0911 0.0891 0.0891
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0048 0.0048
Trypanosoma cruzi transcription factor btf3, putative 0.0025 0.0011 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0066 0.0051 0.0051
Schistosoma mansoni cpg binding protein 0.0195 0.018 0.018
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.0282 0.6031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0328 0.0312 0.0312
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0147 0.0132 0.0132
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0069 0.0055 0.0055
Trichomonas vaginalis prokaryotic DNA topoisomerase, putative 0.025 0.0234 0.4993
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0069 0.0055 0.0055
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.006 0.0045 0.1599
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0059 0.0045 0.0827
Echinococcus granulosus steroid dehydrogenase 0.0016 0.0001 0.0001
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0027 0.0012 0.0012
Trichomonas vaginalis inositol monophosphatase, putative 0.0113 0.0098 0.2087
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0125 0.011 0.2055
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0073 0.1555
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0032 0.0692
Toxoplasma gondii bromodomain-containing protein 0.0014 0.0000000033864 0.0000000033864
Brugia malayi Cell death protein 3 precursor 0.0199 0.0184 0.0184
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0003 0.0002
Brugia malayi oxidoreductase 0.0016 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0062 0.0048 0.102
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.002 0.0006 0.0097
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0098 0.182
Trypanosoma brucei DNA topoisomerase III, putative 0.0257 0.0241 0.0325
Echinococcus multilocularis somatostatin receptor 0.0017 0.0003 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0006 0.0201
Loa Loa (eye worm) cytochrome P450 0.002 0.0006 0.0006
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0091 0.0077 0.0077
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Mycobacterium ulcerans hypothetical protein 0.0021 0.0007 0.0103
Echinococcus multilocularis Niemann Pick C1 protein 0.0085 0.0071 0.0071
Schistosoma mansoni zinc finger protein 0.0023 0.0009 0.0009
Echinococcus granulosus thyroid hormone receptor alpha 0.0069 0.0055 0.0055
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0027 0.0012 0.0015
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0003 0.0003
Echinococcus multilocularis protein patched 0.0026 0.0011 0.0011
Schistosoma mansoni smad1 5 8 and 0.0032 0.0018 0.0018
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Brugia malayi Globin family protein 0.0026 0.0011 0.0011
Loa Loa (eye worm) CYP4Cod1 0.0047 0.0032 0.0032
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0231 0.0216 0.0216
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0101 0.0086 0.1603
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0089 0.0089
Mycobacterium tuberculosis Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) 0.0025 0.001 0.0184
Trypanosoma brucei DNA damage repair protein, putative 0.0023 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.0077 0.0063 0.0063
Echinococcus granulosus cathepsin l cysteine peptidase 0.002 0.0006 0.0006
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0069 0.0055 0.0055
Trypanosoma brucei transcription factor BTF3, putative 0.0025 0.0011 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0147 0.0132 0.0132
Plasmodium falciparum thioredoxin reductase 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable lipase LipD 0.0021 0.0007 0.0115
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0023 0.0023
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.002 0.0006 0.0121
Loa Loa (eye worm) hypothetical protein 0.0067 0.0053 0.0053
Onchocerca volvulus 0.0064 0.005 0.1056
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0109 0.0094 0.0094
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0003 0.0004
Brugia malayi DNA topoisomerase III 0.0257 0.0241 0.0241
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0053 0.0039 0.0039
Loa Loa (eye worm) jmjC domain-containing protein 0.0032 0.0017 0.0017
Echinococcus multilocularis sentrin specific protease 8 0.0077 0.0063 0.0063
Mycobacterium ulcerans citrate (pro-3S)-lyase subunit beta 0.0025 0.001 0.0172
Brugia malayi steroid hormone receptor 0.0147 0.0132 0.0132
Leishmania major DNA topoisomerase III, putative 0.013 0.0115 0.0153
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0001 0.0001
Echinococcus multilocularis ubiquitin specific protease 41 0.0037 0.0023 0.0023
Echinococcus granulosus lysosomal alpha glucosidase 0.0529 0.0511 0.0511
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0003 0.0003
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0023 0.0031
Echinococcus granulosus netrin receptor unc 5 0.0015 0.0001 0.0001
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0061 0.0046 0.0046
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0016 0.0001 0.0001
Schistosoma mansoni DNA topoisomerase II 0.0057 0.0042 0.0042
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0064 0.0049 0.0065
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.023
Trichomonas vaginalis glucosylceramidase, putative 0.0186 0.0171 0.3648
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0147 0.0132 0.0132
Echinococcus granulosus oxidoreductase 0.0016 0.0001 0.0001
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0057 0.0042 0.0778
Schistosoma mansoni prokaryotic DNA topoisomerase 0.0299 0.0283 0.0283
Loa Loa (eye worm) hypothetical protein 0.0048 0.0034 0.0034
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0003 0.0003
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0052 0.0037 0.005
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0119 0.0104 0.0104
Plasmodium falciparum ABC transporter G family member 2 0.0019 0.0005 0.0005
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0062 0.0048 0.0063
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0025 0.0011 0.0011
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0016 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Mycobacterium tuberculosis Probable esterase LipL 0.0021 0.0007 0.0115
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0059 0.0045 0.0815
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) TOPoisomerase family member 0.0057 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0727 0.0709 0.0709
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0051 0.0051
Trichomonas vaginalis hypothetical protein 0.0033 0.0018 0.0392
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.0011 0.023
Onchocerca volvulus 0.0017 0.0003 0.0064
Echinococcus granulosus GTP binding nuclear protein Ran 0.0053 0.0039 0.0039
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0063 0.0048 0.0065
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0167 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0727 0.0709 0.0709
Brugia malayi hypothetical protein 0.0026 0.0011 0.0011
Trypanosoma brucei DNA topoisomerase IB, large subunit 0.7471 0.7411 1
Trypanosoma cruzi hypothetical protein 0.0077 0.0063 0.0083
Mycobacterium tuberculosis Probable hydrolase 0.0021 0.0007 0.0115
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0037 0.0023 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.002 0.0006 0.0097
Onchocerca volvulus 0.0016 0.0001 0.0027
Schistosoma mansoni globin X 0.0026 0.0011 0.0011
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0003 0.0003
Trypanosoma cruzi cytochrome P450, putative 0.0047 0.0032 0.0042
Entamoeba histolytica hypothetical protein 0.0216 0.02 0.7084
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0017 0.0003 0.0004
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0017 0.0003 0.0003
Brugia malayi Muscleblind-like protein 0.0727 0.0709 0.0709
Echinococcus granulosus DNA topoisomerase 1 1.0077 1 1
Mycobacterium ulcerans DNA polymerase IV 0.0099 0.0084 0.1559
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0064 0.0049 0.1047
Schistosoma mansoni ap endonuclease 0.0027 0.0012 0.0012
Echinococcus granulosus Pleckstrin G protein interacting region 0.0017 0.0003 0.0003
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0003 0.0003
Echinococcus granulosus JmjC domain containing protein 4 0.0032 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0167 0.0152 0.0152
Loa Loa (eye worm) latrophilin receptor protein 2 0.0041 0.0026 0.0026
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.055 0.0533 1
Schistosoma mansoni opsin-like receptor 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0003 0.0045
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0003 0.0099
Toxoplasma gondii isocitrate dehydrogenase 0.0063 0.0048 0.0048
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0021 0.0007 0.0007
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0199 0.0184 0.0184
Loa Loa (eye worm) hypothetical protein 0.1181 0.116 0.116
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0023 0.0009 0.0009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0023 0.0023
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0077 0.0063 0.0063
Echinococcus multilocularis Multi antimicrobial extrusion protein MatE 0.006 0.0046 0.0046
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Trypanosoma cruzi polo-like protein kinase, putative 0.0188 0.0173 0.0231
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0147 0.0132 0.0132
Echinococcus multilocularis sterol regulatory element binding protein 0.0026 0.0011 0.0011
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0035 0.0641
Mycobacterium ulcerans hypothetical protein 0.0023 0.0008 0.0129
Schistosoma mansoni multidrug resistance protein 0.0066 0.0052 0.0052
Trypanosoma brucei DNA polymerase kappa, putative 0.0049 0.0034 0.0047
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0026 0.0011 0.0365
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0069 0.0055 0.0072
Trichomonas vaginalis bromodomain-containing protein, putative 0.0171 0.0156 0.3329
Leishmania major hypothetical protein, conserved 0.0032 0.0017 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0073 0.1555
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Plasmodium falciparum flap endonuclease 1 0.0027 0.0012 0.0012
Echinococcus granulosus orexin receptor type 2 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Schistosoma mansoni regulator of G protein signaling 0.002 0.0006 0.0006
Onchocerca volvulus Matrix metalloproteinase homolog 0.0188 0.0173 0.3683
Giardia lamblia DINP protein human, muc B family 0.0079 0.0064 0.2284
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0069 0.0055 0.0055
Brugia malayi G-protein coupled receptor 0.0017 0.0003 0.0003
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.005 0.005
Echinococcus granulosus retinol dehydrogenase 11 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0016 0.0001 0.0012
Schistosoma mansoni jumonji domain containing protein 0.0032 0.0017 0.0017
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0052 0.0037 0.0048
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.0061 0.0083
Schistosoma mansoni mixed-lineage leukemia protein mll 0.004 0.0026 0.0026
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0037 0.0023 0.0817
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Conserved protein 0.0021 0.0007 0.0115
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0063 0.0048 0.0895
Mycobacterium leprae Possible regulatory protein 0.0062 0.0048 0.0873
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi hypothetical protein 0.0026 0.0011 0.0011
Echinococcus granulosus kelch ECH associated protein 1 0.0091 0.0077 0.0077
Trichomonas vaginalis maltase-glucoamylase, putative 0.013 0.0115 0.2461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Schistosoma mansoni Smad4 0.0032 0.0018 0.0018
Mycobacterium ulcerans aldehyde dehydrogenase 0.0192 0.0177 0.3303
Entamoeba histolytica hypothetical protein 0.002 0.0006 0.0201
Schistosoma mansoni amine GPCR 0.0017 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0216 0.02 0.7084
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0084 0.0112
Loa Loa (eye worm) hypothetical protein 0.0102 0.0087 0.0087
Onchocerca volvulus Matrilysin homolog 0.0085 0.007 0.1493
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Onchocerca volvulus 0.002 0.0006 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0023 0.0488
Loa Loa (eye worm) hypothetical protein 0.0025 0.0011 0.0011
Trypanosoma cruzi transcription factor btf3, putative 0.0025 0.0011 0.0013
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0001 0.0048
Schistosoma mansoni aldehyde dehydrogenase 0.0192 0.0177 0.0177
Schistosoma mansoni flap endonuclease-1 0.0024 0.001 0.001
Onchocerca volvulus 0.0026 0.0011 0.0239
Echinococcus multilocularis disintegrin and metalloproteinase 0.0022 0.0008 0.0008
Leishmania major DNA topoisomerase type IB small subunit 0.4044 0.4005 0.5403
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0048 0.0034 0.0727
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0079 0.0064 0.1199
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0082 0.0068 0.0068
Plasmodium vivax basic transcription factor 3b, putative 0.0025 0.0011 0.0011
Onchocerca volvulus 0.002 0.0006 0.0119
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0017 0.0003 0.0033
Giardia lamblia Hypothetical protein 0.0016 0.0001 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0167 0.0152 0.0152
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0003 0.0002
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0003 0.0003
Echinococcus multilocularis regulator of G protein signaling 7 0.0037 0.0023 0.0023
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi Cathepsin L-like precursor 0.002 0.0006 0.0006
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.013 0.0115 0.4081
Echinococcus granulosus cytochrome P450 2K1 0.002 0.0006 0.0006
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0164 0.0149 0.5274
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0104 0.0089 0.0118
Loa Loa (eye worm) hypothetical protein 0.0085 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0017 0.0003 0.0067
Leishmania major cytochrome p450-like protein 0.002 0.0006 0.0006
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.002 0.0006 0.0085
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0017 0.0003 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Brugia malayi hypothetical protein 0.0069 0.0055 0.0055
Echinococcus granulosus histone lysine methyltransferase setb 0.0064 0.005 0.005
Echinococcus granulosus expressed protein 0.0026 0.0011 0.0011
Trypanosoma brucei membrane transporter protein, putative 0.0066 0.0052 0.007
Echinococcus granulosus muscleblind protein 0.0727 0.0709 0.0709
Trypanosoma brucei ISWI complex protein 0.0016 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0124 0.0109 0.0109
Brugia malayi N-terminal motif family protein 0.035 0.0334 0.0334
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0147 0.0132 0.0132
Onchocerca volvulus Serine\/threonine kinase homolog 0.0188 0.0173 0.3684
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0025 0.0011 0.023
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0003 0.0067
Echinococcus multilocularis Blood coagulation inhibitor, Disintegrin 0.014 0.0125 0.0125
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0035 0.0035
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) flap endonuclease-1 0.0027 0.0012 0.0012
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0147 0.0132 0.0132
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0017 0.0003 0.0045
Trypanosoma cruzi metacaspase 5, putative 0.0088 0.0073 0.0096
Echinococcus multilocularis transfer RNA-Lys 0.0177 0.0162 0.0162
Echinococcus granulosus axis inhibition protein axin 0.002 0.0006 0.0006
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0124 0.0109 0.0109
Brugia malayi Cathepsin L-like precursor 0.002 0.0006 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0073 0.1555
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.0253 0.541
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma cruzi hypothetical protein, conserved 0.0023 0.0008 0.0009
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.002 0.0006 0.0085
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0063 0.0048 0.0065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0021 0.0007 0.0103
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0017 0.0003 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0147 0.0132 0.0132
Onchocerca volvulus 0.0016 0.0001 0.0027
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0017 0.0003 0.0033
Echinococcus granulosus caspase 0.0231 0.0216 0.0216
Brugia malayi hypothetical protein 0.0223 0.0208 0.0208
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0003 0.0003
Brugia malayi metalloprotease disintegrin 16 with thrombospondin type I motif 0.0105 0.009 0.009
Schistosoma mansoni survival motor neuron protein 0.0241 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.0041 0.0026 0.0026
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Entamoeba histolytica hypothetical protein, conserved 0.0016 0.0001 0.0048
Loa Loa (eye worm) DNA topoisomerase I 1.0077 1 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0003 0.0003
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) acetyltransferase 0.0582 0.0564 0.0564
Onchocerca volvulus 0.0016 0.0001 0.0027
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0006 0.0006
Echinococcus multilocularis transcription factor btf3 0.0025 0.0011 0.0011
Echinococcus granulosus g protein coupled receptor 0.0017 0.0003 0.0003
Schistosoma mansoni opsin-like receptor 0.0017 0.0003 0.0003
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.002 0.0006 0.0085
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0006 0.0121
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0003 0.0039
Brugia malayi bZIP transcription factor family protein 0.0081 0.0066 0.0066
Brugia malayi Protein kinase domain containing protein 0.0017 0.0002 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0003 0.0003
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0079 0.0064 0.0085
Mycobacterium tuberculosis Possible oxidoreductase 0.0016 0.0001 0.0012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0012
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0019 0.0005 0.007
Brugia malayi nuclear receptor NHR-88 0.0147 0.0132 0.0132
Echinococcus granulosus cpg binding protein 0.0195 0.018 0.018
Plasmodium falciparum topoisomerase I 1.0077 1 1
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0186 0.0171 0.365
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0021 0.0007 0.0007
Schistosoma mansoni jumonji/arid domain-containing protein 0.0128 0.0113 0.0113
Trypanosoma cruzi metacaspase, putative 0.0088 0.0073 0.0096
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0037 0.0037
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0147 0.0132 0.0132
Echinococcus granulosus nuclear receptor nhr 48 0.0069 0.0055 0.0055
Trypanosoma brucei DNA polymerase kappa, putative 0.0057 0.0042 0.0057
Echinococcus granulosus neuropeptide receptor 0.0017 0.0003 0.0003
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0016 0.0001 0.0048
Brugia malayi hypothetical protein 0.0039 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0216 0.02 0.02
Schistosoma mansoni hypothetical protein 0.0911 0.0891 0.0891
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0001 0.0001
Loa Loa (eye worm) TAR-binding protein 0.0109 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.002 0.0006 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.0099 0.0084 0.0112
Schistosoma mansoni family C48 unassigned peptidase (C48 family) 0.0077 0.0063 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Brugia malayi RNA binding protein 0.0109 0.0094 0.0094
Onchocerca volvulus 0.0054 0.004 0.0845
Brugia malayi hypothetical protein 0.0077 0.0063 0.0063
Trypanosoma cruzi DNA topoisomerase III, putative 0.0257 0.0241 0.0323
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0026 0.0011 0.0201
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.013 0.0115 0.2461
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0026 0.0011 0.0189
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Schistosoma mansoni importin beta-1 0.0072 0.0057 0.0057
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0053 0.0039 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0027 0.0012 0.0394
Loa Loa (eye worm) ctsf protein 0.002 0.0006 0.0006
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0016 0.0001 0.0012
Schistosoma mansoni amine GPCR 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0016 0.0002 0.0044
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0019 0.0005 0.007
Schistosoma mansoni cpg binding protein 0.0195 0.018 0.018
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0037 0.0023 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0147 0.0132 0.0132
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0006 0.0006
Echinococcus multilocularis mothers against decapentaplegic 5 0.0032 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0016 0.0002 0.0002
Plasmodium vivax ataxin-2 like protein, putative 0.0102 0.0087 0.0087
Echinococcus multilocularis mixed lineage leukemia protein mll 0.004 0.0026 0.0026
Trichomonas vaginalis conserved hypothetical protein 0.0088 0.0073 0.1555
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.0007 0.0007
Toxoplasma gondii HEAT repeat-containing protein 0.0072 0.0057 0.0057
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0016 0.0001 0.0012
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0003 0.0003
Schistosoma mansoni jumonji domain containing protein 0.0119 0.0104 0.0104
Toxoplasma gondii DNA topoisomerase I, putative 1.0077 1 1
Echinococcus granulosus carbonyl reductase 1 0.0016 0.0001 0.0001
Echinococcus granulosus Ankyrin 0.0015 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0026 0.0011 0.0239
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis retinol dehydrogenase 11 0.0016 0.0001 0.0001
Echinococcus granulosus polybromo 1 0.0019 0.0004 0.0004
Echinococcus multilocularis Kelch repeat type 1 0.0091 0.0077 0.0077
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.0282 1
Mycobacterium ulcerans hypothetical protein 0.0025 0.001 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0173 0.0173
Schistosoma mansoni dep domain containing protein 0.0017 0.0003 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0167 0.0152 0.0152
Echinococcus multilocularis lysine specific demethylase 5A 0.0119 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Brugia malayi beta-lactamase family protein 0.0021 0.0007 0.0007
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0041 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0113 0.0098 0.013
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0104 0.0089 0.3146
Brugia malayi ecdysteroid receptor 0.0147 0.0132 0.0132
Onchocerca volvulus 0.0016 0.0001 0.0027
Schistosoma mansoni axis inhibition protein axin 0.002 0.0006 0.0006
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0016 0.0001 0.0048
Entamoeba histolytica cysteine protease, putative 0.002 0.0006 0.0201
Trichomonas vaginalis conserved hypothetical protein 0.0016 0.0002 0.004
Echinococcus granulosus ATP binding cassette sub family G 0.0019 0.0005 0.0005
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0027 0.0012 0.0012
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0051 0.0051
Echinococcus granulosus Nuclear hormone receptor HR96 0.0069 0.0055 0.0055
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.0007 0.0007
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0125 0.011 0.2045
Echinococcus multilocularis sex peptide receptor 0.0017 0.0003 0.0003
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0003 0.0002
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Echinococcus multilocularis zinc finger protein 0.0023 0.0009 0.0009
Schistosoma mansoni gabp alpha 0.0078 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni apoferritin-2 0.0026 0.0011 0.0011
Trichomonas vaginalis histone acetyltransferase gcn5, putative 0.0016 0.0002 0.0044
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0019 0.0005 0.0005
Trichomonas vaginalis Clan CE, family C48, Ulp1-like cysteine peptidase 0.0077 0.0063 0.1335
Brugia malayi Uncoordinated protein 44 0.0015 0.0001 0.0001
Echinococcus multilocularis cathepsin L cysteine protease 0.002 0.0006 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0147 0.0132 0.0132
Giardia lamblia GTOR 0.0047 0.0032 0.1147
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0164 0.0149 0.0149
Echinococcus granulosus microtubule associated protein 2 0.3028 0.2995 0.2995
Brugia malayi MH2 domain containing protein 0.0032 0.0018 0.0018
Trypanosoma brucei SUMO1/Ulp2, putative 0.0025 0.0011 0.0015
Echinococcus multilocularis dna polymerase eta 0.0116 0.0101 0.0101
Echinococcus granulosus neuropeptide receptor 0.0017 0.0003 0.0003
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0053 0.0039 0.0039
Echinococcus multilocularis importin subunit beta 1 0.0072 0.0057 0.0057
Toxoplasma gondii DNA topoisomerase family protein 0.025 0.0234 0.0234
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0016 0.0001 0.0029
Loa Loa (eye worm) hypothetical protein 0.0129 0.0114 0.0114
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0016 0.0001 0.0001
Leishmania major DNA polymerase kappa, putative 0.0079 0.0064 0.0085
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0001 0.0001
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0104 0.0089 0.0118
Mycobacterium tuberculosis DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) (nicking-c 0.012 0.0105 0.1953
Trypanosoma cruzi major cysteine proteinase, putative 0.006 0.0045 0.0059
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0011
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0035 0.0035
Loa Loa (eye worm) Ulp1 protease 0.0025 0.0011 0.0011
Echinococcus granulosus cathepsin l1 0.002 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0001 0.0001
Echinococcus multilocularis thyroid hormone receptor alpha 0.0147 0.0132 0.0132
Brugia malayi conserved hypotetical protein 0.0069 0.0055 0.0055
Brugia malayi Steroid receptor seven-up type 2 0.0147 0.0132 0.0132
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0064 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Echinococcus granulosus single minded 2 0.0177 0.0162 0.0162
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0011 0.0227
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.0061 0.0081
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0017 0.0003 0.0002
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0176 0.016 0.016
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.002 0.0006 0.0085
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0016 0.0001 0.0001
Brugia malayi Latrophilin receptor protein 2 0.0041 0.0026 0.0026
Trichomonas vaginalis alpha-glucosidase, putative 0.0048 0.0034 0.0727
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) dehydrogenase 0.0016 0.0001 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0017 0.0003 0.0033
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0035 0.002 0.0437
Brugia malayi Cytochrome P450 family protein 0.0047 0.0032 0.0032
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0094 0.0094
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0063 0.0048 0.0048
Echinococcus granulosus neuropeptide receptor A26 0.0287 0.0271 0.0271
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0037 0.0023 0.0029
Loa Loa (eye worm) DnaJ domain-containing protein 0.0105 0.009 0.009
Brugia malayi dehydrogenases, short chain protein 2 0.0016 0.0001 0.0001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0008 0.0008
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0147 0.0132 0.0132
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0016 0.0001 0.0001
Brugia malayi MH2 domain containing protein 0.0475 0.0458 0.0458
Onchocerca volvulus 0.002 0.0006 0.0119
Plasmodium falciparum ataxin-2 like protein, putative 0.0102 0.0087 0.0087
Brugia malayi Dehydrogenases, short chain protein 2 0.0016 0.0001 0.0001
Echinococcus multilocularis cathepsin l cysteine peptidase 0.002 0.0006 0.0006
Entamoeba histolytica Ulp1 protease family, C-terminal catalytic domain containing protein 0.0077 0.0063 0.2213
Brugia malayi hypothetical protein 0.0064 0.0049 0.0049
Trypanosoma brucei metacaspase 0.0088 0.0073 0.0098
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0003 0.0003
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0003 0.0003
Trypanosoma cruzi PAB1-binding protein , putative 0.0102 0.0087 0.0116
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0026 0.0011 0.0239
Loa Loa (eye worm) hypothetical protein 0.0077 0.0063 0.0063
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0021 0.0007 0.0115
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0003 0.0003
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0131 0.2434
Echinococcus multilocularis retinol dehydrogenase 13 0.0016 0.0001 0.0001
Trypanosoma cruzi metacaspase 5, putative 0.0088 0.0073 0.0096
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0003 0.0003
Echinococcus multilocularis citrate lyase subunit beta protein 0.0025 0.001 0.001
Loa Loa (eye worm) hypothetical protein 0.0044 0.003 0.003
Mycobacterium ulcerans lipase LipD 0.0021 0.0007 0.0103
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0006 0.0006
Schistosoma mansoni polybromo-1 0.0019 0.0004 0.0004
Echinococcus multilocularis lysosomal alpha glucosidase 0.0529 0.0511 0.0511
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0021 0.0007 0.0007
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0044 0.003 0.0547
Trichomonas vaginalis PIKK family atypical protein kinase 0.0047 0.0032 0.0692
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0017 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0094 0.0094
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0108 0.0093 0.0093
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0017 0.0003 0.0033
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Toxoplasma gondii ABC1 family protein 0.0021 0.0007 0.0007
Chlamydia trachomatis deubiquitinase/deneddylase Dub1 0.0025 0.0011 0.0292
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0003 0.0003
Echinococcus multilocularis isocitrate dehydrogenase 0.0063 0.0048 0.0048
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Brugia malayi Nuclear hormone receptor-like 1 0.0077 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0077 0.0063 0.0063
Trypanosoma brucei Metacaspase-4 0.0088 0.0073 0.0098
Schistosoma mansoni caspase-7 (C14 family) 0.0231 0.0216 0.0216
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0103 0.0088 0.1648
Schistosoma mansoni hypothetical protein 0.0017 0.0003 0.0003
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0016 0.0001 0.0002
Brugia malayi MH1 domain containing protein 0.0018 0.0004 0.0004
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Brugia malayi Flap endonuclease-1 0.0027 0.0012 0.0012
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0003 0.0003
Brugia malayi Melibiase family protein 0.0071 0.0057 0.0057
Brugia malayi Niemann-Pick C1 protein precursor 0.006 0.0045 0.0045
Echinococcus multilocularis GA binding protein alpha chain 0.0078 0.0064 0.0064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.0109 0.0094 0.0094
Brugia malayi Fli-1 protein 0.0237 0.0222 0.0222
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.0161 0.3446
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi TAR-binding protein 0.0109 0.0094 0.0094
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0023 0.0488
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0016 0.0001 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Brugia malayi Cathepsin L-like precursor 0.002 0.0006 0.0006
Schistosoma mansoni dishevelled 0.0017 0.0003 0.0003
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.0282 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0147 0.0132 0.0132
Trypanosoma cruzi DNA damage repair protein, putative 0.0023 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0017 0.0003 0.0003
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.3146
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0007 0.0007
Loa Loa (eye worm) RGS-3 protein 0.002 0.0006 0.0006
Onchocerca volvulus 0.0021 0.0007 0.0143
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0006 0.0006
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0016 0.0001 0.0001
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0037 0.0023 0.0023
Echinococcus multilocularis geminin 0.0911 0.0891 0.0891
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0016 0.0001 0.0001
Leishmania major mitochondrial DNA topoisomerase II 0.0057 0.0042 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0014 0.0291
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.0253 0.541
Onchocerca volvulus 0.0017 0.0003 0.0067
Brugia malayi Papain family cysteine protease containing protein 0.002 0.0006 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.002 0.0437
Mycobacterium tuberculosis Conserved protein 0.0025 0.001 0.0184
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.002 0.0006 0.0097
Onchocerca volvulus 0.0033 0.0019 0.0396
Loa Loa (eye worm) hypothetical protein 0.0147 0.0132 0.0132
Brugia malayi jmjC domain containing protein 0.0032 0.0017 0.0017
Trypanosoma brucei metacaspase MCA3 0.0088 0.0073 0.0098
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0016 0.0001 0.0012
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0041 0.0026 0.0026
Echinococcus granulosus transcription factor btf3 0.0025 0.0011 0.0011
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0098 0.182
Brugia malayi Inositol-1 0.0113 0.0098 0.0098
Onchocerca volvulus 0.0223 0.0208 0.443
Brugia malayi Pax transcription factor protein 2 0.0478 0.0461 0.0461
Mycobacterium tuberculosis Conserved hypothetical protein 0.0268 0.0253 0.4734
Onchocerca volvulus 0.012 0.0105 0.2245
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Brugia malayi regulator of G-protein signaling egl-10 0.0037 0.0023 0.0023
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Schistosoma mansoni myst-related protein 0.0018 0.0004 0.0004
Echinococcus granulosus importin subunit beta 1 0.0072 0.0057 0.0057
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0147 0.0132 0.0132
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0088 0.0073 0.0073
Echinococcus granulosus flap endonuclease 1 0.0027 0.0012 0.0012
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.013 0.0115 0.0115
Schistosoma mansoni nuclear hormone receptor 0.0069 0.0055 0.0055
Schistosoma mansoni patched 1 0.0026 0.0011 0.0011
Onchocerca volvulus 0.0017 0.0003 0.0067
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0058 0.0044 0.0938
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0098 0.182
Brugia malayi Ulp1 protease family, C-terminal catalytic domain containing protein 0.0025 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0088 0.0073 0.0073
Echinococcus multilocularis conserved hypothetical protein 0.0016 0.0001 0.0001
Schistosoma mansoni DNA polymerase eta 0.0116 0.0101 0.0101
Echinococcus multilocularis steroid dehydrogenase 0.0016 0.0001 0.0001
Echinococcus granulosus jumonji domain containing 1A 0.0032 0.0017 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0176 0.016 0.016
Mycobacterium ulcerans acyl-CoA synthetase 0.0017 0.0003 0.0033
Echinococcus multilocularis serotonin receptor 0.0017 0.0003 0.0003
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0001 0.0002
Brugia malayi nuclear hormone receptor 0.0069 0.0055 0.0055
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0073 0.0058 0.0058
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0047 0.0032 0.0032
Mycobacterium ulcerans hypothetical protein 0.0268 0.0253 0.4727
Trypanosoma cruzi 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative 0.0025 0.001 0.0012
Plasmodium vivax vivapain-2 0.002 0.0006 0.0006
Schistosoma mansoni hypothetical protein 0.177 0.1745 0.1745
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni lamin 0.0054 0.004 0.004
Trichomonas vaginalis sentrin/sumo-specific protease, senp8, putative 0.0025 0.0011 0.023
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0012
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0008 0.0011
Mycobacterium tuberculosis Probable oxidoreductase 0.0016 0.0001 0.0012
Schistosoma mansoni hypothetical protein 0.0158 0.0142 0.0142
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Echinococcus multilocularis Ankyrin 0.0015 0.0001 0.0001
Echinococcus multilocularis nuclear receptor nhr 48 0.0069 0.0055 0.0055
Schistosoma mansoni hypothetical protein 0.0025 0.001 0.001
Schistosoma mansoni neuropeptide receptor 0.0017 0.0003 0.0003
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0047 0.0032 0.0042
Toxoplasma gondii DNA topoisomerase 2, putative 0.0057 0.0042 0.0042
Echinococcus multilocularis carbonyl reductase 1 0.0016 0.0001 0.0001
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0104 0.0089 0.0118
Schistosoma mansoni RAR-like nuclear receptor 0.0147 0.0132 0.0132
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Giardia lamblia Short-chain dehydrogenase, putative 0.0016 0.0001 0.0048
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0098 0.182
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0023 0.0009 0.0009
Echinococcus granulosus death domain containing protein 0.0015 0.0001 0.0001
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Onchocerca volvulus 0.0017 0.0003 0.0067
Brugia malayi nuclear hormone receptor family member odr-7 0.0069 0.0055 0.0055
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0011 0.0234
Schistosoma mansoni inositol monophosphatase 0.0113 0.0098 0.0098
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0103 0.0088 0.0088
Leishmania major cathepsin L-like protease 0.0076 0.0061 0.0081
Giardia lamblia ABC transporter 0.0019 0.0005 0.0172
Trichomonas vaginalis D-aminoacylase, putative 0.0021 0.0007 0.0146
Trypanosoma brucei short-chain dehydrogenase, putative 0.0016 0.0001 0.0002
Toxoplasma gondii cathepsin CPL 0.002 0.0006 0.0006
Echinococcus multilocularis cysteine protease 0.002 0.0006 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0241 0.0225 0.0304
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0167 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0003 0.006
Brugia malayi nuclear hormone receptor 0.0147 0.0132 0.0132
Brugia malayi Cathepsin L-like precursor 0.002 0.0006 0.0006
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0113 0.0098 0.2087
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.4165 0.4125 0.4125
Schistosoma mansoni adenoreceptor 0.0017 0.0003 0.0003
Onchocerca volvulus Sepiapterin reductase homolog 0.0016 0.0001 0.0027
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0047 0.0032 0.0032
Plasmodium falciparum acyl-CoA synthetase 0.0044 0.003 0.003
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.002 0.0006 0.0121
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0015 0.0015
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0042 0.0027 0.0502
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0004 0.0094
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0053 0.0038 0.0038
Trichomonas vaginalis PIKK family atypical protein kinase 0.0016 0.0001 0.0031
Loa Loa (eye worm) hypothetical protein 0.0037 0.0023 0.0023
Schistosoma mansoni short chain dehydrogenase 0.0016 0.0001 0.0001
Brugia malayi MH1 domain containing protein 0.0032 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Trypanosoma cruzi DNA topoisomerase IA, putative 0.025 0.0234 0.0314
Echinococcus multilocularis dna polymerase kappa 0.0099 0.0084 0.0084
Schistosoma mansoni histamine h1 receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0023 0.0493
Leishmania major hypothetical protein, conserved 0.0021 0.0007 0.0008
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0037 0.0023 0.0493
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0063 0.0048 0.0048
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0006 0.0006
Mycobacterium ulcerans monooxygenase 0.0026 0.0011 0.0187
Schistosoma mansoni steroid dehydrogenase 0.0016 0.0001 0.0001
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0016 0.0001 0.0012
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.002 0.0006 0.0008
Loa Loa (eye worm) hypothetical protein 0.0069 0.0055 0.0055
Leishmania major DNA polymerase eta, putative 0.0066 0.0051 0.0067
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Plasmodium vivax JmjC domain containing protein 0.0032 0.0017 0.0017
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.002 0.0006 0.0085
Echinococcus granulosus axis inhibition protein axin 0.002 0.0006 0.0006
Brugia malayi hypothetical protein 0.0017 0.0003 0.0003
Onchocerca volvulus 0.0017 0.0003 0.0067
Brugia malayi jmjC domain containing protein 0.0119 0.0104 0.0104
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0027 0.0012 0.0012
Onchocerca volvulus 0.0016 0.0001 0.0027
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0003 0.0067
Trypanosoma brucei DNA polymerase kappa, putative 0.0099 0.0084 0.0114
Echinococcus granulosus tar DNA binding protein 0.0109 0.0094 0.0094
Entamoeba histolytica short chain dehydrogenase family protein 0.0016 0.0001 0.0048
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0057 0.0042 0.0896
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0119 0.0104 0.0104
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Schistosoma mansoni ran 0.0053 0.0039 0.0039
Echinococcus granulosus Blood coagulation inhibitor Disintegrin 0.014 0.0125 0.0125
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0016 0.0001 0.0012
Echinococcus granulosus protein tyrosine kinase 0.0181 0.0165 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0173 0.3686
Echinococcus granulosus histone acetyltransferase KAT2B 0.0171 0.0156 0.0156
Echinococcus multilocularis ecdysone induced protein 78C 0.0147 0.0132 0.0132
Brugia malayi hypothetical protein 0.0316 0.03 0.03
Toxoplasma gondii C-5 cytosine-specific DNA methylase superfamily protein 0.0019 0.0005 0.0005
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0104 0.0089 0.0089
Echinococcus multilocularis cysteine protease 0.002 0.0006 0.0006
Entamoeba histolytica Flap nuclease, putative 0.0027 0.0012 0.0434
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0021 0.0007 0.0008
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0069 0.0055 0.0055
Schistosoma mansoni ferritin 0.0026 0.0011 0.0011
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0067 0.0053 0.0053
Plasmodium vivax SET domain containing protein 0.002 0.0006 0.0006
Echinococcus multilocularis caspase 2 0.0199 0.0184 0.0184
Onchocerca volvulus 0.0241 0.0225 0.4809
Entamoeba histolytica protein kinase, putative 0.0104 0.0089 0.3146
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0027 0.0012 0.0015
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0003 0.0003
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0016 0.0001 0.0029
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0062 0.0048 0.102
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0035 0.002 0.0437
Loa Loa (eye worm) hypothetical protein 0.0017 0.0003 0.0003
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0003 0.0003
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0006 0.0006
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.002 0.0437
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.002 0.0006 0.0097
Schistosoma mansoni apoferritin-2 0.0026 0.0011 0.0011
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0053 0.0039 0.0039
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0047 0.0032 0.0042
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0017 0.0003 0.0033
Leishmania major SUMO1/Ulp2, putative,cysteine peptidase, Clan CA, family C48, putative 0.0025 0.0011 0.0013
Onchocerca volvulus Protein ultraspiracle homolog 0.0147 0.0132 0.2807
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0003 0.0003
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0016 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0026 0.0011 0.0011
Schistosoma mansoni caspase-3 (C14 family) 0.0231 0.0216 0.0216
Plasmodium falciparum cysteine proteinase falcipain 3 0.002 0.0006 0.0006
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0171 0.0156 0.0156
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.002 0.0006 0.0097
Mycobacterium ulcerans acyl-CoA synthetase 0.0059 0.0045 0.0815
Brugia malayi MH1 domain containing protein 0.0032 0.0018 0.0018
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0088 0.0073 0.1555
Schistosoma mansoni coup transcription factor 0.0147 0.0132 0.0132
Loa Loa (eye worm) globin family protein 0.0026 0.0011 0.0011
Brugia malayi latrophilin 2 splice variant baaae 0.0088 0.0074 0.0074
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0017 0.0003 0.0003
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0016 0.0001 0.0027
Echinococcus multilocularis ATPase family AAA domain containing protein 2B 0.0014 0.00000014189 0.00000014189
Echinococcus granulosus phd:f box containing protein 0.0032 0.0017 0.0017
Echinococcus multilocularis ATP binding cassette sub family G 0.0019 0.0005 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0066 0.0052 0.0068
Trichomonas vaginalis glucosylceramidase, putative 0.0269 0.0253 0.541
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0044 0.003 0.0989
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0016 0.0001 0.0001
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0017 0.0003 0.0002
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0147 0.0132 0.0132
Leishmania major DNA topoisomerase III, putative 0.0299 0.0283 0.038
Toxoplasma gondii thioredoxin reductase 0.0049 0.0035 0.0035
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0073 0.0058 0.0058
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0147 0.0132 0.0132
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0063 0.0048 0.0063
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0147 0.0132 0.0132
Entamoeba histolytica DNA topoisomerase III, putative 0.013 0.0115 0.4073
Onchocerca volvulus Matrilysin homolog 0.0188 0.0173 0.3683
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0016 0.0001 0.0012
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0131 0.2444
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0063 0.0048 0.0048
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0003 0.0003
Trichomonas vaginalis Citrate lyase beta chain, putative 0.0025 0.001 0.0224
Trypanosoma cruzi ABC transporter, putative 0.0019 0.0005 0.0005

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 8 nM Inhibition of TACE using scintillation proximity assay (SPA) ChEMBL. 11708926
IC50 (binding) = 8 nM Inhibition of TACE using scintillation proximity assay (SPA) ChEMBL. 11708926
IC50 (binding) = 17 nM Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloproteinase-3 ChEMBL. 11708926
IC50 (binding) = 17 nM Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloproteinase-3 ChEMBL. 11708926
IC50 (binding) = 22 nM Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloproteinase-9 ChEMBL. 11708926
IC50 (binding) = 22 nM Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloproteinase-9 ChEMBL. 11708926
IC50 (functional) = 28 nM Inhibition of lipopolysaccharide(LPS) induced TNF release in human mono nuclear cells ChEMBL. 11708926
IC50 (functional) = 28 nM Inhibition of lipopolysaccharide(LPS) induced TNF release in human mono nuclear cells ChEMBL. 11708926
IC50 (binding) = 52 nM Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloproteinase-1 ChEMBL. 11708926
IC50 (binding) = 52 nM Inhibition potency was determined by fluorescence-based peptide assay against matrix metalloproteinase-1 ChEMBL. 11708926
Inhibition (functional) = -5 % Inhibition of soluble TNF-alpha production in LPS-Stimulated mice by administration of 40 mg/kg compound per orally ChEMBL. 11708926
Inhibition (functional) = -5 % Inhibition of soluble TNF-alpha production in LPS-Stimulated mice by administration of 40 mg/kg compound per orally ChEMBL. 11708926
Inhibition (functional) 0 % Inhibition of soluble TNF-alpha production in LPS-Stimulated mice by administration of 40 mg/kg compound subcutaneously; Not determined ChEMBL. 11708926
S 0 mg ml-1 Solubility in simulated gastric fluid; Not determined ChEMBL. 11708926

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 11708926

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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