Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0028 | 0.1017 | 0.2884 | |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0019 | 0.0547 | 0.0154 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0018 | 0.0488 | 0.0666 |
Mycobacterium ulcerans | polyketide synthase | 0.0029 | 0.113 | 0.0772 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.1128 | 0.1004 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0031 | 0.1237 | 0.1955 |
Leishmania major | importin beta-1 subunit, putative | 0.0014 | 0.0212 | 0.0573 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0024 | 0.0804 | 0.0675 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0035 | 0.1435 | 0.1391 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0018 | 0.0488 | 0.0666 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0021 | 0.0647 | 0.0516 |
Plasmodium vivax | hypothetical protein, conserved | 0.0017 | 0.0411 | 0.2104 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0172 | 0.9465 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0021 | 0.0647 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0373 | 0.0238 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0031 | 0.1237 | 0.1955 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0025 | 0.0843 | 0.0927 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0018 | 0.0488 | 0.0666 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0021 | 0.0647 | 0.0545 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0403 |
Toxoplasma gondii | ABC1 family protein | 0.0021 | 0.0647 | 0.3921 |
Mycobacterium ulcerans | glutaminase | 0.0161 | 0.8814 | 1 |
Mycobacterium ulcerans | lipase LipD | 0.0021 | 0.0647 | 0.0191 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0018 | 0.0488 | 0.2697 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0488 | 0.2697 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0017 | 0.0411 | 0.0277 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0031 | 0.1237 | 0.169 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0018 | 0.0488 | 0.0666 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0018 | 0.0488 | 0.0666 |
Giardia lamblia | PHD finger protein 15 | 0.0017 | 0.0411 | 0.0293 |
Echinococcus multilocularis | geminin | 0.01 | 0.5239 | 0.5172 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0019 | 0.0525 | 0.2985 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0488 | 0.2697 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0021 | 0.0634 | 0.3823 |
Brugia malayi | PHD-finger family protein | 0.0017 | 0.0411 | 0.0315 |
Brugia malayi | jmjC domain containing protein | 0.0056 | 0.2693 | 0.2945 |
Loa Loa (eye worm) | fatty acid synthase | 0.0029 | 0.1107 | 0.0983 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0018 | 0.0488 | 0.0666 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0018 | 0.0488 | 0.0666 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0021 | 0.0647 | 0.0516 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0018 | 0.0488 | 0.0355 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0021 | 0.0647 | 0.0883 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0135 | 0.7323 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.04 | 0.0266 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0035 | 0.1435 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.0647 | 0.3921 |
Onchocerca volvulus | 0.0021 | 0.0647 | 0.1121 | |
Mycobacterium ulcerans | hypothetical protein | 0.0021 | 0.0647 | 0.0191 |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.0018 | 0.0488 | 0.2697 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0021 | 0.0647 | 0.0545 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0044 | 0.1982 | 0.3899 |
Loa Loa (eye worm) | glutaminase | 0.0161 | 0.8814 | 0.8798 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0021 | 0.0647 | 0.0883 |
Loa Loa (eye worm) | glutaminase 2 | 0.0161 | 0.8814 | 0.8798 |
Mycobacterium ulcerans | beta-lactamase | 0.0021 | 0.0647 | 0.0191 |
Entamoeba histolytica | hypothetical protein | 0.0014 | 0.0212 | 0.008 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0031 | 0.1237 | 0.1955 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0021 | 0.0647 | 0.0545 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0017 | 0.0411 | 0.0277 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0021 | 0.0647 | 0.3921 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0021 | 0.0647 | 0.0545 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0021 | 0.0647 | 0.0586 |
Echinococcus multilocularis | snurportin 1 | 0.0181 | 1 | 1 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0029 | 0.113 | 0.1544 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0084 | 0.4321 | 0.4603 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0056 | 0.2673 | 0.2921 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0035 | 0.1435 | 0.1391 |
Loa Loa (eye worm) | acyl carrier protein | 0.0014 | 0.02 | 0.0063 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0029 | 0.113 | 0.1544 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0044 | 0.1982 | 0.1795 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0647 | 0.0516 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0035 | 0.1435 | 0.1315 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0035 | 0.1435 | 1 |
Brugia malayi | Importin beta-1 subunit | 0.0017 | 0.04 | 0.0302 |
Schistosoma mansoni | jumonji domain containing protein | 0.0045 | 0.2018 | 0.1906 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0035 | 0.1435 | 0.1138 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0019 | 0.0547 | 0.0071 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0021 | 0.0647 | 0.0516 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0044 | 0.1982 | 0.2707 |
Brugia malayi | beta-lactamase | 0.0021 | 0.0647 | 0.0586 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0018 | 0.0488 | 0.0666 |
Brugia malayi | AMP-binding enzyme family protein | 0.0028 | 0.1017 | 0.1013 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0029 | 0.113 | 0.1676 |
Plasmodium vivax | hypothetical protein, conserved | 0.0021 | 0.0647 | 0.3921 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0017 | 0.0411 | 0.0277 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0017 | 0.04 | 0.0266 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0021 | 0.0622 | 0.0491 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0411 | 0.0277 |
Echinococcus granulosus | importin subunit beta 1 | 0.0017 | 0.04 | 0.0266 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0035 | 0.1435 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0017 | 0.0411 | 0.2104 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0018 | 0.0488 | 0.2697 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0018 | 0.0488 | 0.0666 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0018 | 0.0488 | 0.0666 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0035 | 0.1435 | 0.1315 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0647 | 0.0516 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0029 | 0.1078 | 0.1471 |
Brugia malayi | glutaminase DH11.1 | 0.0161 | 0.8814 | 1 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0084 | 0.4321 | 0.59 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0029 | 0.1078 | 0.1471 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0018 | 0.0488 | 0.0666 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0031 | 0.1237 | 0.09 |
Mycobacterium ulcerans | polyketide synthase | 0.0031 | 0.1237 | 0.09 |
Toxoplasma gondii | exonuclease III APE | 0.0035 | 0.1435 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0014 | 0.0212 | 0.008 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.0018 | 0.0488 | 0.2697 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0355 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0031 | 0.1237 | 0.169 |
Plasmodium falciparum | importin beta, putative | 0.0017 | 0.04 | 0.2019 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0021 | 0.0647 | 0.0516 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0084 | 0.4321 | 1 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0044 | 0.1982 | 0.2707 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0015 | 0.0278 | 0.1082 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0056 | 0.2693 | 0.2591 |
Loa Loa (eye worm) | beta-lactamase | 0.0021 | 0.0647 | 0.0516 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0028 | 0.1017 | 0.1389 |
Onchocerca volvulus | 0.0021 | 0.0647 | 0.1121 | |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0021 | 0.0622 | 0.0491 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0018 | 0.0488 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0647 | 0.0516 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0017 | 0.0387 | 0.0529 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0029 | 0.113 | 0.1144 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.0024 | 0.0794 | 0.0798 |
Loa Loa (eye worm) | cytochrome P450 | 0.0018 | 0.0488 | 0.0355 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks15 | 0.0012 | 0.0104 | 0.0143 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0035 | 0.1479 | 0.136 |
Mycobacterium leprae | conserved hypothetical protein | 0.0021 | 0.0647 | 0.0414 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0035 | 0.1435 | 0.1391 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0411 | 0.0277 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0018 | 0.0488 | 0.2697 |
Plasmodium falciparum | phd finger protein, putative | 0.0017 | 0.0411 | 0.2104 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0018 | 0.0488 | 0.0666 |
Brugia malayi | cytochrome P450 | 0.0018 | 0.0488 | 0.0403 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0021 | 0.0622 | 0.0491 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0018 | 0.0488 | 0.0666 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.0018 | 0.0488 | 0.2697 |
Brugia malayi | RNA, U transporter 1 | 0.0048 | 0.2229 | 0.241 |
Plasmodium vivax | importin-beta 2, putative | 0.0017 | 0.04 | 0.2019 |
Mycobacterium leprae | Probable lipase LipE | 0.0021 | 0.0647 | 0.0414 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0018 | 0.0488 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0647 | 0.0516 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0172 | 0.9465 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0035 | 0.1435 | 0.1495 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0018 | 0.0488 | 0.0355 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0021 | 0.0647 | 0.0883 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0021 | 0.0622 | 0.0491 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0017 | 0.0411 | 0.0277 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0021 | 0.0647 | 0.0883 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0021 | 0.0647 | 0.0883 |
Schistosoma mansoni | cytochrome P450 | 0.0018 | 0.0488 | 0.0355 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0024 | 0.0817 | 0.1115 |
Mycobacterium ulcerans | thioesterase TesA | 0.0025 | 0.0843 | 0.0427 |
Mycobacterium tuberculosis | Conserved protein | 0.0021 | 0.0647 | 0.0883 |
Echinococcus granulosus | peregrin | 0.0017 | 0.0411 | 0.0277 |
Mycobacterium ulcerans | thioesterase | 0.0025 | 0.0843 | 0.0427 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0029 | 0.113 | 0.1544 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0014 | 0.0212 | 0.0573 |
Trichomonas vaginalis | esterase, putative | 0.0021 | 0.0647 | 0.0545 |
Trichomonas vaginalis | glutaminase, putative | 0.0161 | 0.8814 | 0.9302 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0031 | 0.1237 | 0.09 |
Schistosoma mansoni | glutaminase | 0.0161 | 0.8814 | 0.8798 |
Schistosoma mansoni | hypothetical protein | 0.0018 | 0.0488 | 0.0355 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0031 | 0.1237 | 0.169 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0018 | 0.0488 | 0.0666 |
Schistosoma mansoni | hypothetical protein | 0.0181 | 1 | 1 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0029 | 0.113 | 0.0772 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0029 | 0.113 | 0.1676 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0018 | 0.0488 | 0.2697 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0021 | 0.0647 | 0.0883 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2302 | 0.2194 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0021 | 0.0647 | 0.0191 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0021 | 0.0647 | 0.0883 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0014 | 0.0212 | 0.008 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0035 | 0.1435 | 0.5 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0029 | 0.113 | 0.0772 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0403 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0017 | 0.04 | 0.0266 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.5239 | 0.5172 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0029 | 0.113 | 0.0772 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0021 | 0.0647 | 0.0586 |
Echinococcus granulosus | jumonji domain containing protein | 0.0024 | 0.0804 | 0.0675 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.0024 | 0.0794 | 0.0367 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0035 | 0.1435 | 0.1391 |
Schistosoma mansoni | ap endonuclease | 0.0035 | 0.1435 | 0.1315 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0031 | 0.1237 | 0.8474 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0029 | 0.113 | 0.0772 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0018 | 0.0488 | 0.0666 |
Leishmania major | cytochrome p450-like protein | 0.0018 | 0.0488 | 0.2697 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0021 | 0.0647 | 0.3921 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0018 | 0.0488 | 0.0666 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0017 | 0.04 | 0.2019 |
Echinococcus multilocularis | 0.0018 | 0.0488 | 0.0355 | |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0018 | 0.0488 | 0.0666 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0035 | 0.1435 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0017 | 0.04 | 0.2019 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0035 | 0.1435 | 0.1315 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0021 | 0.0647 | 0.0516 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0021 | 0.0647 | 0.3921 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0024 | 0.0794 | 0.0367 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0181 | 1 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0403 |
Schistosoma mansoni | ap endonuclease | 0.0035 | 0.1435 | 0.1315 |
Brugia malayi | Cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0403 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0355 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0053 | 0.2513 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0021 | 0.0622 | 0.0491 |
Brugia malayi | Bromodomain containing protein | 0.0017 | 0.0411 | 0.0315 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0017 | 0.04 | 0.2019 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0056 | 0.2693 | 0.2591 |
Brugia malayi | beta-lactamase family protein | 0.0021 | 0.0647 | 0.0586 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0019 | 0.0547 | 0.0071 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0017 | 0.0411 | 0.2104 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0647 | 0.0516 |
Echinococcus granulosus | geminin | 0.01 | 0.5239 | 0.5172 |
Brugia malayi | jmjC domain containing protein | 0.0021 | 0.0622 | 0.0558 |
Onchocerca volvulus | 0.0051 | 0.2406 | 0.9491 | |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0035 | 0.1435 | 1 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0035 | 0.1435 | 0.196 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0025 | 0.0843 | 0.1151 |
Trypanosoma brucei | cytochrome P450, putative | 0.0018 | 0.0488 | 0.2697 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.5239 | 0.5172 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0021 | 0.0647 | 0.0545 |
Echinococcus multilocularis | peregrin | 0.0017 | 0.0411 | 0.0277 |
Trichomonas vaginalis | importin beta-1, putative | 0.0014 | 0.0212 | 0.008 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0018 | 0.0488 | 0.0666 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.0018 | 0.0488 | 0.2697 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0172 | 0.9465 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0021 | 0.0647 | 0.0883 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0035 | 0.1435 | 1 |
Onchocerca volvulus | 0.0021 | 0.0647 | 0.1121 | |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0021 | 0.0645 | 0.0881 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0647 | 0.0516 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0018 | 0.0488 | 0.0355 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0028 | 0.1017 | 0.0891 |
Mycobacterium tuberculosis | Conserved protein | 0.0021 | 0.0647 | 0.0883 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 38.6 ug ml-1 | Inhibitory activity against Candida albicans (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC (functional) | = 38.6 ug ml-1 | Inhibitory activity against Candida albicans (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC (functional) | = 41.9 ug ml-1 | Inhibitory activity against Candida albicans (40 clinical isolates), determined at pH-7.2 | ChEMBL. | 7473549 |
MIC (functional) | = 41.9 ug ml-1 | Inhibitory activity against Candida albicans (40 clinical isolates), determined at pH-7.2 | ChEMBL. | 7473549 |
MIC (functional) | = 114.4 ug ml-1 | Inhibitory activity against Candida. species. (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC (functional) | = 191.3 ug ml-1 | Inhibitory activity against Candida. species. (40 clinical isolates), determined at pH-7.2 | ChEMBL. | 7473549 |
MIC50 (functional) | = 16 ug ml-1 | 50% inhibitory activity against Candida albicans (40 clinical isolates) determined at pH-7.2 | ChEMBL. | 7473549 |
MIC50 (functional) | = 16 ug ml-1 | 50% inhibitory activity against Candida albicans (40 clinical isolates) determined at pH-5.8 | ChEMBL. | 7473549 |
MIC50 (functional) | = 16 ug ml-1 | 50% inhibitory activity against Candida albicans (40 clinical isolates) determined at pH-7.2 | ChEMBL. | 7473549 |
MIC50 (functional) | = 16 ug ml-1 | 50% inhibitory activity against Candida albicans (40 clinical isolates) determined at pH-5.8 | ChEMBL. | 7473549 |
MIC50 (functional) | = 64 ug ml-1 | Inhibitory activity against Candida .species (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC50 (functional) | = 128 ug ml-1 | 50% inhibitory activity against the Candida. species (40 clinical isolates) was determined at pH-7.2 | ChEMBL. | 7473549 |
MIC90 (functional) | = 64 ug ml-1 | Inhibitory activity against the Candida albicans (40 clinical isolates), determined at pH-7.2 | ChEMBL. | 7473549 |
MIC90 (functional) | = 64 ug ml-1 | Inhibitory activity against the Candida albicans (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC90 (functional) | = 64 ug ml-1 | Inhibitory activity against Candida .species (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC90 (functional) | = 64 ug ml-1 | Inhibitory activity against the Candida albicans (40 clinical isolates), determined at pH-7.2 | ChEMBL. | 7473549 |
MIC90 (functional) | = 64 ug ml-1 | Inhibitory activity against the Candida albicans (40 clinical isolates), determined at pH-5.8 | ChEMBL. | 7473549 |
MIC90 (functional) | = 256 ug ml-1 | 90% inhibitory activity against Candida. species (40 clinical isolates) determined at pH-7.2 | ChEMBL. | 7473549 |
R (functional) | = 0 % | Resistance against Candida. albicans (40 clinical isolates) at 256 microg/mL (pH=7.2), activity is expressed as R%. | ChEMBL. | 7473549 |
R (functional) | = 0 % | Percent resistance against Candida albicans (40 clinical isolates) at 256 micro g/mL (pH=5.8), activity is expressed as R%. | ChEMBL. | 7473549 |
R (functional) | = 0 % | Resistance against all Candida. species (40 clinical isolates) at 256 micro g/mL (pH=5.8). Activity is expressed as R%. | ChEMBL. | 7473549 |
R (functional) | = 0 % | Resistance against Candida. albicans (40 clinical isolates) at 256 microg/mL (pH=7.2), activity is expressed as R%. | ChEMBL. | 7473549 |
R (functional) | = 0 % | Percent resistance against Candida albicans (40 clinical isolates) at 256 micro g/mL (pH=5.8), activity is expressed as R%. | ChEMBL. | 7473549 |
R (functional) | = 20 % | Percent resistance against all Candida. species (40 clinical isolates) at 256 micro g/mL (pH=7.2), activity is expressed as R%. | ChEMBL. | 7473549 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.