Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0604 | 1 | 1 | |
Onchocerca volvulus | 0.0195 | 0.3148 | 0.3148 | |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | slit | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Peroxidasin | 0.0604 | 1 | 1 |
Brugia malayi | Muscle positioning protein 4 | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0604 | 1 | 1 |
Onchocerca volvulus | Neurogenic locus notch homolog | 0.0195 | 0.3148 | 0.3148 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0148 | 0.235 | 0.235 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | fibropellin Ia | 0.0195 | 0.3148 | 0.3148 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0013 | 0.0095 | 0.5 |
Echinococcus granulosus | slit 2 protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | notch | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0301 |
Brugia malayi | Animal haem peroxidase family protein | 0.0604 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0345 | 0.0345 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0041 | 0.0561 | 0.0561 |
Brugia malayi | Animal haem peroxidase family protein | 0.0604 | 1 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0013 | 0.0095 | 0.0095 |
Echinococcus granulosus | notch | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | peroxidasin | 0.0604 | 1 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.0345 | 0.0345 |
Echinococcus multilocularis | fat cadherin tumor suppressor | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Cadherin domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Delta serrate ligand family protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | GPCR, family 2 | 0.0013 | 0.0094 | 0.0094 |
Onchocerca volvulus | Peroxidasin homolog | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | septate junction protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Giardia lamblia | High cysteine protein | 0.0195 | 0.3148 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Echinococcus multilocularis | fibropellin Ia | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Echinococcus multilocularis | neurogenic locus notch protein 4 | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | slit 2 protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Onchocerca volvulus | Dual oxidase homolog | 0.0604 | 1 | 1 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0013 | 0.0095 | 0.5 |
Echinococcus granulosus | protein jagged 1 | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | Notch2 | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0013 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0345 | 0.0345 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0013 | 0.0094 | 0.0094 |
Schistosoma mansoni | notch | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | laminin gamma-3 chain | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | notch | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Cadherin domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | delta-like protein 1 | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0094 | 0.0094 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Onchocerca volvulus | Peroxidase homolog | 0.0604 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Echinococcus granulosus | protein jagged 1 | 0.0195 | 0.3148 | 0.3148 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0301 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0013 | 0.0095 | 0.5 |
Brugia malayi | Blistered cuticle protein 3 | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0561 | 0.0561 |
Schistosoma mansoni | notch | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.235 | 0.235 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0013 | 0.0095 | 0.5 |
Schistosoma mansoni | Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] | 0.0195 | 0.3148 | 0.3148 |
Toxoplasma gondii | EGF family domain-containing protein | 0.0195 | 0.3148 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 0.0561 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Echinococcus granulosus | neurogenic locus protein delta | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0195 | 0.3148 | 0.3148 | |
Brugia malayi | Animal haem peroxidase family protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0195 | 0.3148 | 0.3148 |
Onchocerca volvulus | Putative cubilin | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Echinococcus multilocularis | neural cadherin | 0.0195 | 0.3148 | 0.3148 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0013 | 0.0095 | 0.5 |
Brugia malayi | Animal haem peroxidase family protein | 0.0604 | 1 | 1 |
Onchocerca volvulus | Slit protein homolog | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0013 | 0.0095 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0094 | 0.0094 |
Schistosoma mansoni | cell polarity protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | notch protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | protein jagged 2 | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0013 | 0.0095 | 0.5 |
Onchocerca volvulus | 0.0195 | 0.3148 | 0.3148 | |
Brugia malayi | Isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Schistosoma mansoni | peroxidasin | 0.0604 | 1 | 1 |
Onchocerca volvulus | 0.0195 | 0.3148 | 0.3148 | |
Brugia malayi | GCC2 and GCC3 family protein | 0.0195 | 0.3148 | 0.3148 |
Onchocerca volvulus | 0.0195 | 0.3148 | 0.3148 | |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Onchocerca volvulus | Peroxidasin homolog | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0013 | 0.0094 | 0.0094 |
Echinococcus granulosus | GPCR family 2 | 0.0013 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Echinococcus multilocularis | neurogenic locus notch protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | neurogenic locus notch protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0604 | 1 | 1 |
Echinococcus granulosus | neural cadherin | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | neurogenic locus notch protein 4 | 0.0195 | 0.3148 | 0.3148 |
Echinococcus granulosus | peroxidasin | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0094 | 0.0094 |
Onchocerca volvulus | Neurogenic locus notch protein homolog | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Animal haem peroxidase family protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Onchocerca volvulus | Chorion peroxidase homolog | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | peroxidasin | 0.0604 | 1 | 1 |
Echinococcus multilocularis | protein jagged 1 | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 0.0561 | 0.0561 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Echinococcus granulosus | protein jagged 2 | 0.0195 | 0.3148 | 0.3148 |
Onchocerca volvulus | 0.0604 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Schistosoma mansoni | notch | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | neurogenic locus protein delta | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0094 | 0.0094 |
Brugia malayi | N-terminal motif family protein | 0.0148 | 0.235 | 0.235 |
Onchocerca volvulus | Peroxidase homolog | 0.0604 | 1 | 1 |
Onchocerca volvulus | 0.0604 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0013 | 0.0095 | 0.5 |
Schistosoma mansoni | notch | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | protein jagged 1 | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | notch-like transmembrane receptor | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | EGF-like domain containing protein | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0604 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0094 | 0.0094 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | protein jagged 2 | 0.0195 | 0.3148 | 0.3148 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | Transmembrane cell adhesion receptor mua-3 precursor, putative | 0.0195 | 0.3148 | 0.3148 |
Echinococcus multilocularis | notch | 0.0195 | 0.3148 | 0.3148 |
Brugia malayi | isocitrate dehydrogenase | 0.0013 | 0.0095 | 0.0095 |
Loa Loa (eye worm) | animal heme peroxidase | 0.0604 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.