Detailed information for compound 233434

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 596.225 | Formula: C14H19N2O18P3------
  • H donors: 3 H acceptors: 13 LogP: -8.07 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 3
  • SMILES: OCC1O[C@@H](O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2OP(=O)([O-])[O-])n2cncc2)[C@H]([C@H]([C@@H]1OP(=O)([O-])[O-])OP(=O)([O-])[O-])O
  • InChi: 1S/C14H25N2O18P3/c17-3-6-9(12(34-37(26,27)28)13(29-6)16-2-1-15-5-16)31-14-8(19)11(33-36(23,24)25)10(7(4-18)30-14)32-35(20,21)22/h1-2,5-14,17-19H,3-4H2,(H2,20,21,22)(H2,23,24,25)(H2,26,27,28)/p-6/t6-,7?,8?,9+,10?,11-,12?,13-,14+/m1/s1
  • InChiKey: MTNHUHLRIWUBKK-LTVMIXMMSA-H  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0003 0.0003
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0046 0.0355 0.0355
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0071 0.0658 0.1093
Onchocerca volvulus 0.0067 0.0606 0.0964
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0097 0.0977 0.0985
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0067 0.0606 0.0744
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0046 0.0355 0.0352
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0046 0.0355 0.0352
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0097 0.0977 0.1592
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0524 0.4931
Plasmodium vivax hypothetical protein, conserved 0.007 0.0648 0.6127
Onchocerca volvulus 0.0097 0.0977 0.1592
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0176 0.1637
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0176 0.0175
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0046 0.0355 0.0352
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0033 0.0203 0.0247
Trypanosoma brucei unspecified product 0.0023 0.0078 0.0655
Echinococcus granulosus sex peptide receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) MH2 domain-containing protein 0.0127 0.133 0.2228
Schistosoma mansoni rab6-interacting 0.002 0.0038 0.0043
Giardia lamblia Nitric oxide synthase, inducible 0.0026 0.0109 0.2427
Chlamydia trachomatis sulfite reductase 0.0018 0.0015 0.0721
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.2603 0.3207
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0566 0.0938
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.8109 0.8199
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0176 0.0176
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis g protein coupled receptor 0.0067 0.0606 0.061
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0648 0.2426
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.001 0.0025
Plasmodium falciparum glutathione reductase 0.005 0.0406 0.3803
Entamoeba histolytica hypothetical protein 0.0071 0.066 1
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0283 0.0283
Onchocerca volvulus 0.0067 0.0606 0.0964
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Trypanosoma brucei DNA polymerase IV, putative 0.0053 0.0444 0.4169
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.0606 0.061
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0597 0.5639
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0648 0.6127
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0038 0.0043
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Brugia malayi nuclear receptor NHR-88 0.0207 0.2295 0.3858
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0067 0.0606 0.1007
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0524 0.4931
Schistosoma mansoni hypothetical protein 0.0067 0.0606 0.0744
Schistosoma mansoni tar DNA-binding protein 0.0255 0.2882 0.3551
Schistosoma mansoni nuclear receptor 0.0097 0.0977 0.1201
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0176 0.0213
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.0606 0.061
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Trichomonas vaginalis DNA polymerase eta, putative 0.006 0.0524 0.1957
Mycobacterium tuberculosis Probable reductase 0.0114 0.1183 0.1183
Echinococcus multilocularis lamin 0.0054 0.0451 0.0453
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0147 0.0178
Loa Loa (eye worm) nuclear hormone receptor 0.0097 0.0977 0.163
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.0606 0.061
Echinococcus multilocularis carboxylesterase 5A 0.0069 0.0634 0.0638
Echinococcus granulosus methionine synthase reductase 0.0018 0.0015 0.0015
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0361 0.0362
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0038 0.0261 0.0318
Brugia malayi exodeoxyribonuclease III family protein 0.0038 0.0261 0.0424
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Brugia malayi Cytochrome P450 family protein 0.0122 0.1276 0.2137
Schistosoma mansoni loxhd1 0.002 0.0038 0.0043
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0067 0.0606 0.0744
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0112 0.0126
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0158 0.1418
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0161 0.1489
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0001
Brugia malayi Doublecortin family protein 0.002 0.0038 0.0047
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Brugia malayi FAD binding domain containing protein 0.0018 0.0015 0.0009
Schistosoma mansoni peroxidasin 0.0026 0.0112 0.0134
Loa Loa (eye worm) hypothetical protein 0.0025 0.0102 0.0154
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.2603 0.2629
Toxoplasma gondii exonuclease III APE 0.0038 0.0261 0.2448
Loa Loa (eye worm) DR-78 0.0097 0.0977 0.163
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0207 0.2295 0.2827
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0161 0.0194
Schistosoma mansoni cytochrome P450 reductase 0.0029 0.0148 0.0179
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0648 0.0648
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0176 0.1594
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0083 0.008
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0035 0.0228 0.2131
Brugia malayi hypothetical protein 0.002 0.0038 0.0047
Brugia malayi Fli-1 protein 0.0216 0.2406 0.4046
Brugia malayi Nuclear hormone receptor-like 1 0.0109 0.1118 0.1871
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.0606 0.1005
Echinococcus granulosus geminin 0.0669 0.7883 0.9721
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0525 0.0644
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0067 0.0606 0.0744
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0648 0.1076
Schistosoma mansoni neuropeptide receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.007 0.0648 0.1076
Brugia malayi nuclear receptor NHR-67 0.0097 0.0977 0.1632
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0112 0.0126
Loa Loa (eye worm) acetylcholinesterase 1 0.0069 0.0634 0.1052
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0097 0.0977 0.1592
Brugia malayi Carboxylesterase family protein 0.0069 0.0634 0.1054
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0176 0.1594
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0308 0.0457
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0207 0.2295 0.2318
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0597 0.5639
Echinococcus multilocularis serotonin receptor 0.0067 0.0606 0.061
Echinococcus granulosus G protein coupled receptor 139 0.0067 0.0606 0.0744
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0023 0.0083 0.008
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0127 0.1337 1
Schistosoma mansoni hypothetical protein 0.0067 0.0606 0.0744
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0003 0.0003
Brugia malayi hypothetical protein 0.002 0.0038 0.0047
Echinococcus multilocularis lamin dm0 0.0054 0.0451 0.0453
Echinococcus granulosus neuropeptide FF receptor 2 0.0067 0.0606 0.0744
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0648 0.2426
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0046 0.0355 0.3313
Onchocerca volvulus 0.0067 0.0606 0.0964
Brugia malayi Dopamine receptor protein 2 0.0067 0.0606 0.1007
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0203 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0207 0.2295 0.3858
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0038 0.0261 0.2409
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0067 0.0606 0.061
Trypanosoma cruzi p450 reductase, putative 0.0029 0.0148 0.1329
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus nuclear receptor nhr 48 0.0097 0.0977 0.1201
Brugia malayi nuclear hormone receptor family member nhr-6 0.0097 0.0977 0.1632
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0114 0.0112
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0262 0.0261
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0121
Mycobacterium leprae putative cytochrome p450 0.0046 0.0355 0.2638
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0176 0.028
Loa Loa (eye worm) hypothetical protein 0.0083 0.0801 0.1334
Trichomonas vaginalis chromobox protein, putative 0.007 0.0642 0.2401
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) doublecortin family protein 0.002 0.0038 0.0045
Echinococcus multilocularis serotonin receptor 0.0067 0.0606 0.061
Brugia malayi hypothetical protein 0.0097 0.0977 0.1632
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0067 0.0606 0.0744
Schistosoma mansoni biogenic amine receptor 0.0067 0.0606 0.0744
Onchocerca volvulus 0.0067 0.0606 0.0964
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0046 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Loa Loa (eye worm) hypothetical protein 0.003 0.0161 0.0252
Brugia malayi MH2 domain containing protein 0.0127 0.133 0.223
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0207 0.2295 0.2318
Trypanosoma cruzi DNA polymerase eta, putative 0.0035 0.0228 0.2091
Brugia malayi GnHR receptor homolog 0.0067 0.0606 0.1007
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0746 0.1241
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0046 0.0355 0.0352
Loa Loa (eye worm) CYP4Cod1 0.0063 0.0566 0.0938
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0051 0.0417 0.391
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0081 1
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0038 0.027
Schistosoma mansoni polycystin 1-related 0.002 0.0038 0.0043
Brugia malayi conserved hypotetical protein 0.0097 0.0977 0.1632
Echinococcus granulosus cytochrome P450 2K1 0.0046 0.0355 0.0434
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0083 0.0703
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0746 0.0751
Leishmania major hypothetical protein, conserved 0.0104 0.1052 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0046 0.0355 0.0355
Echinococcus granulosus g protein coupled receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus lamin dm0 0.0054 0.0451 0.0553
Brugia malayi cytochrome P450 0.0046 0.0355 0.0583
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0121
Schistosoma mansoni chromobox protein 0.007 0.0642 0.0787
Brugia malayi Calcitonin receptor-like protein seb-1 0.0248 0.279 0.4694
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0067 0.0606 0.1007
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0207 0.2295 0.2827
Echinococcus granulosus carboxylesterase 5A 0.0069 0.0634 0.0778
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.001 0.0259
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.2051 0.2071
Trichomonas vaginalis chromobox protein, putative 0.007 0.0642 0.2401
Brugia malayi nuclear hormone receptor 0.0097 0.0977 0.1632
Loa Loa (eye worm) hypothetical protein 0.0104 0.1052 0.1757
Loa Loa (eye worm) hypothetical protein 0.0109 0.1118 0.1869
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0112 0.0126
Plasmodium vivax glycogen synthase kinase 3, putative 0.0051 0.0417 0.391
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Plasmodium vivax glutathione reductase, putative 0.005 0.0406 0.3803
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0112 0.0173
Trypanosoma cruzi cytochrome P450, putative 0.0063 0.0566 0.5342
Schistosoma mansoni tar DNA-binding protein 0.0255 0.2882 0.3551
Onchocerca volvulus 0.0031 0.017 0.0223
Loa Loa (eye worm) hypothetical protein 0.007 0.0648 0.1076
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0097 0.0977 0.1201
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0122 0.1279 0.1574
Schistosoma mansoni ap endonuclease 0.0038 0.0261 0.0318
Echinococcus multilocularis chromobox protein 1 0.007 0.0642 0.0646
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0361 0.0442
Loa Loa (eye worm) steroid hormone receptor 0.0207 0.2295 0.3856
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0207 0.2295 0.3828
Brugia malayi Heterochromatin protein 1 0.007 0.0642 0.1067
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0012 0.0008
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.1183 0.1183
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0029 0.0148 0.1329
Trichomonas vaginalis sulfite reductase, putative 0.0029 0.0148 0.0546
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0046 0.0355 0.0355
Plasmodium vivax ataxin-2 like protein, putative 0.0104 0.1052 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.1225 0.1507
Schistosoma mansoni intermediate filament proteins 0.0054 0.0451 0.0553
Loa Loa (eye worm) hypothetical protein 0.0058 0.0506 0.0836
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0067 0.0606 0.0744
Onchocerca volvulus 0.0237 0.2662 0.4451
Loa Loa (eye worm) cytochrome P450 family protein 0.0122 0.1276 0.2135
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0746 0.0916
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus multilocularis dna polymerase eta 0.0058 0.0506 0.0509
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0112 0.0173
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0033 0.0203 0.0202
Schistosoma mansoni amine GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.0045
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0081 0.0734
Echinococcus multilocularis protein kinase shaggy 0.0051 0.0417 0.0419
Brugia malayi Melatonin receptor type 1A 0.0067 0.0606 0.1007
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.0606 0.1005
Echinococcus granulosus microtubule associated protein 2 0.0688 0.8109 1
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0046 0.0355 0.0355
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0207 0.2295 0.3858
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0012 0.0012
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0083 0.0599
Brugia malayi intermediate filament protein 0.0054 0.0451 0.0745
Loa Loa (eye worm) TYRA-2 protein 0.0067 0.0606 0.1005
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0029 0.0148 0.1329
Loa Loa (eye worm) hypothetical protein 0.0109 0.1118 0.1869
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Onchocerca volvulus 0.0026 0.0112 0.0126
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0648 0.0648
Schistosoma mansoni hypothetical protein 0.002 0.0038 0.0043
Onchocerca volvulus 0.0067 0.0606 0.0964
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0417 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0029 0.0148 0.1329
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0067 0.0606 0.1005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Brugia malayi nuclear hormone receptor 0.0207 0.2295 0.3858
Onchocerca volvulus Peroxidase homolog 0.0026 0.0112 0.0126
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0175
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0112 0.017
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0261 0.2409
Onchocerca volvulus 0.0083 0.0801 0.1294
Brugia malayi G protein-coupled receptor 0.0067 0.0606 0.1007
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0029 0.0148 0.1329
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0001
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0597 0.5639
Brugia malayi nuclear receptor NHR-88 0.0097 0.0977 0.1632
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0046 0.0355 0.3313
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0029 0.0148 0.0147
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Echinococcus multilocularis fmrfamide receptor 0.0067 0.0606 0.061
Brugia malayi nuclear hormone receptor family member odr-7 0.0097 0.0977 0.1632
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0029 0.0148 0.1329
Onchocerca volvulus 0.0067 0.0606 0.0964
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0029 0.0148 0.1329
Mycobacterium ulcerans lipase LipD 0.007 0.0648 0.0645
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0046 0.0355 0.0352
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0597 0.0733
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0417 0.0686
Schistosoma mansoni opsin-like receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.007 0.0648 0.1076
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0248 0.279 0.4693
Brugia malayi G-protein coupled receptor 0.0067 0.0606 0.1007
Brugia malayi sulfakinin receptor protein 0.0067 0.0606 0.1007
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus neuropeptide receptor 0.0067 0.0606 0.0744
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0417 0.5808
Trypanosoma brucei unspecified product 0.0023 0.0078 0.0655
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0038 0.0043
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.1183 0.1183
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.2051 0.2526
Schistosoma mansoni nuclear receptor nhr-48 0.0097 0.0977 0.1201
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0046 0.0355 0.0352
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.0606 0.0744
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0746 0.1243
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0207 0.2295 0.3858
Loa Loa (eye worm) hypothetical protein 0.0029 0.0148 0.0232
Brugia malayi ecdysteroid receptor 0.0508 0.5932 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0067 0.0606 0.061
Brugia malayi ORL1-like opioid receptor 0.0067 0.0606 0.1007
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0083 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0524 0.4931
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0083 0.0124
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0029 0.0148 0.0145
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0449 0.522 0.522
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Onchocerca volvulus 0.0067 0.0606 0.0964
Onchocerca volvulus 0.0023 0.0083 0.0076
Schistosoma mansoni nuclear hormone receptor 0.0207 0.2295 0.2827
Leishmania major cytochrome p450-like protein 0.0063 0.0566 0.5342
Schistosoma mansoni peroxidasin 0.0026 0.0112 0.0134
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0746 0.1243
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0492
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0038 0.0043
Echinococcus granulosus lamin 0.0054 0.0451 0.0553
Mycobacterium tuberculosis Conserved protein 0.007 0.0648 0.0648
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0046 0.0355 0.0355
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0038 0.0035
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0051 0.0417 0.3941
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0207 0.2295 0.2827
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0746 0.0751
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0112 0.0173
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Brugia malayi putative neuropeptide receptor 0.0067 0.0606 0.1007
Echinococcus multilocularis G-protein coupled receptor, putative 0.0067 0.0606 0.061
Brugia malayi N-terminal motif family protein 0.0179 0.1957 0.3288
Echinococcus granulosus protein kinase shaggy 0.0051 0.0417 0.0511
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.2051 0.3446
Echinococcus granulosus intermediate filament protein 0.0054 0.0451 0.0553
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0081 0.0686
Echinococcus multilocularis 0.0046 0.0355 0.0356
Loa Loa (eye worm) FAD binding domain-containing protein 0.0018 0.0015 0.0007
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.3035
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0207 0.2295 0.3858
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.006 0.0524 0.1957
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0207 0.2295 0.3858
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0081 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0081 0.0734
Echinococcus granulosus serotonin receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0149 0.0233
Echinococcus granulosus 7tm_1 domain containing protein 0.0067 0.0606 0.0744
Leishmania major trypanothione reductase 0.005 0.0406 0.3803
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0372 0.0611
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0176 0.1594
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0067 0.0606 0.061
Schistosoma mansoni amine GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0031 0.017 0.0268
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0046 0.0355 0.0355
Mycobacterium tuberculosis Conserved hypothetical protein 0.0033 0.0203 0.0203
Schistosoma mansoni lamin 0.0054 0.0451 0.0553
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0051 0.0417 0.0686
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0038 0.0261 0.2409
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0067 0.0606 0.0744
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0298 0.0364
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0038 0.0261 0.2409
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0038 0.0261 0.3103
Onchocerca volvulus 0.0067 0.0606 0.0964
Loa Loa (eye worm) hypothetical protein 0.0054 0.0451 0.0743
Brugia malayi RNA binding protein 0.0255 0.2882 0.4849
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0046 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Schistosoma mansoni neuropeptide f receptor 76f 0.0067 0.0606 0.0744
Echinococcus granulosus dro:myosuppressin receptor 0.0067 0.0606 0.0744
Brugia malayi larval opioid receptor 0.0067 0.0606 0.1007
Schistosoma mansoni opsin-like receptor 0.0067 0.0606 0.0744
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.001 0.001
Brugia malayi Blistered cuticle protein 3 0.0026 0.0112 0.0173
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0097 0.0977 0.1201
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0262 0.0319
Brugia malayi AKH receptor 0.0067 0.0606 0.1007
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0207 0.2295 0.3858
Loa Loa (eye worm) fli-1 protein 0.0216 0.2406 0.4044
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0525 0.0522
Schistosoma mansoni thyroid hormone receptor 0.0329 0.3774 0.4651
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0038 0.0261 0.0261
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Brugia malayi hypothetical protein 0.0067 0.0608 0.101
Echinococcus granulosus g-protein coupled receptor 0.0067 0.0606 0.0744
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0272 0.101
Echinococcus granulosus hypothetical protein 0.0067 0.0606 0.0744
Loa Loa (eye worm) TAR-binding protein 0.0255 0.2882 0.4848
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0046 0.0355 0.0352
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0801 0.0807
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0272 0.0396
Toxoplasma gondii ABC1 family protein 0.007 0.0648 0.6147
Brugia malayi nuclear receptor RXR 0.0097 0.0977 0.1632
Leishmania major cytochrome p450-like protein 0.0046 0.0355 0.3313
Schistosoma mansoni hypothetical protein 0.0078 0.0746 0.0916
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.2051 0.2526
Onchocerca volvulus 0.007 0.0648 0.1035
Entamoeba histolytica hypothetical protein 0.0071 0.066 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0097 0.0977 0.163
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0029 0.0148 0.0179
Schistosoma mansoni growth hormone secretagogue receptor 0.0067 0.0606 0.0744
Brugia malayi Ets-domain containing protein 0.0071 0.0658 0.1095
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0046 0.0355 0.0355
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.2051 0.2526
Toxoplasma gondii LsmAD domain-containing protein 0.0104 0.1052 1
Onchocerca volvulus 0.0067 0.0606 0.0964
Onchocerca volvulus 0.0207 0.2295 0.3828
Brugia malayi Tachykinin-like peptides receptor 99D 0.0067 0.0606 0.1007
Echinococcus multilocularis somatostatin receptor 0.0067 0.0606 0.061
Brugia malayi Pre-SET motif family protein 0.003 0.0161 0.0254
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0026 0.0109 0.0397
Echinococcus granulosus FTZ F1 alpha 0.0207 0.2295 0.2827
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0207 0.2295 0.2827
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.066 0.0664
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0112 0.017
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0176 0.1594
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0038 0.0261 0.6161
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0012 0.0224
Schistosoma mansoni hypothetical protein 0.0067 0.0606 0.0744
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0083 0.003
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0207 0.2295 0.3856
Schistosoma mansoni myosin xvIII 0.0067 0.0606 0.0744
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0597 0.0733
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.8109 1
Onchocerca volvulus 0.007 0.0648 0.1035
Onchocerca volvulus 0.0026 0.0112 0.0126
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0046 0.0355 0.0352
Brugia malayi RNA recognition motif domain containing protein 0.0255 0.2882 0.4849
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Onchocerca volvulus 0.0054 0.0451 0.0701
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0046 0.0355 0.0352
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0046 0.0355 0.0352
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0046 0.0355 0.0352
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0038 0.0035
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0046 0.0355 0.0352
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0051 0.0417 0.0419
Trypanosoma cruzi DNA polymerase kappa, putative 0.006 0.0524 0.4931
Echinococcus granulosus fmrfamide receptor 0.0067 0.0606 0.0744
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.001 0.0259
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0046 0.0355 0.0355
Leishmania major p450 reductase, putative 0.0029 0.0148 0.1329
Mycobacterium ulcerans acyl-CoA synthetase 0.0023 0.0083 0.008
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.0606 0.061
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0112 0.017
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.001 0.0007
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0029 0.0148 0.1329
Brugia malayi steroid hormone receptor 0.0207 0.2295 0.3858
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0067 0.0606 0.0744
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0046 0.0355 0.3313
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0207 0.2295 0.3856
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus chromobox protein 1 0.007 0.0642 0.0787
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0207 0.2295 0.2827
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0097 0.0977 0.1201
Trypanosoma brucei unspecified product 0.0053 0.0444 0.4169
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0207 0.2295 0.3856
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0161 0.0194
Schistosoma mansoni opsin-like receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0179 0.1957 0.3255
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0597 0.5639
Schistosoma mansoni hypothetical protein 0.0067 0.0606 0.0744
Echinococcus granulosus g protein coupled receptor 0.0067 0.0606 0.0744
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0283 0.262
Loa Loa (eye worm) hypothetical protein 0.0025 0.0102 0.0154
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0029 0.0148 0.0179
Trypanosoma brucei DNA polymerase eta, putative 0.0058 0.0506 0.4762
Loa Loa (eye worm) hypothetical protein 0.0039 0.0272 0.044
Schistosoma mansoni tar DNA-binding protein 0.0255 0.2882 0.3551
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Echinococcus multilocularis sex peptide receptor 0.0067 0.0606 0.061
Echinococcus granulosus Nuclear hormone receptor HR96 0.0097 0.0977 0.1201
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0308 0.1145
Schistosoma mansoni ets-related 0.0216 0.2406 0.2964
Schistosoma mansoni gabp alpha 0.0071 0.0658 0.0808
Echinococcus granulosus acetylcholinesterase 0.0069 0.0634 0.0778
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0207 0.2295 0.2827
Brugia malayi hypothetical protein 0.0109 0.1118 0.1871
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.3035
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0207 0.2295 0.2827
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0046 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.002 0.0038 0.0045
Echinococcus granulosus neuropeptides capa receptor 0.0067 0.0606 0.0744
Schistosoma mansoni hypothetical protein 0.0669 0.7883 0.9721
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0525 0.0644
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0109 0.1118 0.1869
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.1183 0.1183
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0207 0.2295 0.3856
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0081 0.0686
Leishmania major DNA polymerase eta, putative 0.0035 0.0228 0.2091
Echinococcus granulosus 7TM GPCR rhodopsin 0.0067 0.0606 0.0744
Schistosoma mansoni neuropeptide receptor 0.0067 0.0606 0.0744
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0114 0.0137
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Giardia lamblia Kinase, CMGC GSK 0.0051 0.0417 1
Plasmodium falciparum thioredoxin reductase 0.005 0.0406 0.3803
Onchocerca volvulus 0.0067 0.0606 0.0964
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0012 0.0015
Brugia malayi Nuclear hormone receptor-like 1 0.0109 0.1118 0.1871
Mycobacterium ulcerans beta-lactamase 0.007 0.0648 0.0645
Echinococcus multilocularis neuropeptide receptor 0.0067 0.0606 0.061
Echinococcus multilocularis neuropeptide receptor A26 0.0067 0.0606 0.061
Echinococcus multilocularis allatostatin A receptor 0.0067 0.0606 0.061
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0245 0.226
Brugia malayi Pre-SET motif family protein 0.0208 0.2314 0.3891
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0029 0.0148 0.0147
Onchocerca volvulus Protein ultraspiracle homolog 0.0207 0.2295 0.3828
Loa Loa (eye worm) hypothetical protein 0.0179 0.1957 0.3286
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0038 0.0261 0.2409
Loa Loa (eye worm) hypothetical protein 0.0037 0.0245 0.0395
Loa Loa (eye worm) hypothetical protein 0.007 0.0648 0.1076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0001
Onchocerca volvulus 0.0051 0.0417 0.0643
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Loa Loa (eye worm) hypothetical protein 0.0069 0.0634 0.1052
Brugia malayi isocitrate dehydrogenase 0.0031 0.0176 0.028
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0081 0.0686
Onchocerca volvulus 0.0097 0.0977 0.1592
Brugia malayi Serotonin receptor 0.0067 0.0606 0.1007
Brugia malayi RE15519p 0.0067 0.0606 0.1007
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0648 0.0645
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0161 0.0194
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0524 0.0521
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0597 0.099
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0127 0.1337 0.1337
Loa Loa (eye worm) G-protein coupled receptor 0.0067 0.0606 0.1005
Schistosoma mansoni nuclear receptor 0.0097 0.0977 0.1201
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0109 0.1118 0.1375
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0161 0.0159
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0207 0.2295 0.3858
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0081 0.0686
Brugia malayi hypothetical protein 0.0147 0.1572 0.2637
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0029 0.0148 0.1329
Echinococcus multilocularis neuropeptides capa receptor 0.0067 0.0606 0.061
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0648 0.6127
Echinococcus multilocularis orexin receptor type 2 0.0067 0.0606 0.061
Brugia malayi glutathione reductase 0.005 0.0406 0.0669
Entamoeba histolytica protein kinase domain containing protein 0.0051 0.0417 0.5808
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0046 0.0355 0.3313
Echinococcus granulosus chromobox protein 1 0.007 0.0642 0.0787
Schistosoma mansoni rab6-interacting 0.002 0.0038 0.0043
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0207 0.2295 0.2318
Brugia malayi photoreceptor-specific nuclear receptor 0.0207 0.2295 0.3858
Echinococcus multilocularis g protein coupled receptor 0.0067 0.0606 0.061
Brugia malayi neuropeptide F receptor 0.0067 0.0606 0.1007
Entamoeba histolytica hypothetical protein 0.0071 0.066 1
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0109 0.1118 0.1127
Echinococcus granulosus somatostatin receptor 0.0067 0.0606 0.0744
Echinococcus granulosus peroxidasin 0.0026 0.0112 0.0134
Brugia malayi orphan nuclear receptor NR2E1 0.0097 0.0977 0.1632
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Brugia malayi hypothetical protein 0.0097 0.0977 0.1632
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0255 0.2882 0.4848
Brugia malayi polk-prov protein 0.0037 0.0245 0.0397
Onchocerca volvulus Neuropeptide F receptor homolog 0.0067 0.0606 0.0964
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0046 0.0355 0.0352
Brugia malayi putative neuropeptide receptor NPR1 0.0067 0.0606 0.1007
Echinococcus multilocularis g protein coupled receptor 0.0067 0.0606 0.061
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0648 0.0652
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0272 0.101
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Echinococcus granulosus GPCR family 2 0.0078 0.0746 0.0916
Onchocerca volvulus 0.0067 0.0606 0.0964
Brugia malayi G protein-coupled receptor F59B2.13 0.0067 0.0606 0.1007
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis musashi 0.0054 0.0451 0.0453
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0161 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0134 0.0492
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0038 0.0261 0.2409
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0067 0.0606 0.1005
Schistosoma mansoni adenoreceptor 0.0067 0.0606 0.0744
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0207 0.2295 0.3858
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0023 0.0083 0.0083
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0067 0.0606 0.1007
Mycobacterium ulcerans hypothetical protein 0.0023 0.0083 0.008
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0023 0.0083 0.008
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0097 0.0977 0.0985
Schistosoma mansoni hypothetical protein 0.0078 0.0746 0.0916
Entamoeba histolytica hypothetical protein 0.0071 0.066 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0525 0.0522
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Onchocerca volvulus 0.007 0.0648 0.1035
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.1183 0.1183
Brugia malayi G-protein coupled receptor 0.0067 0.0606 0.1007
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0207 0.2295 0.3856
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0046 0.0355 0.0352
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Schistosoma mansoni cytochrome P450 0.0046 0.0355 0.0434
Schistosoma mansoni lipoxygenase 0.0118 0.1225 0.1507
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0308 0.1145
Schistosoma mansoni amine GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Brugia malayi TAR-binding protein 0.0255 0.2882 0.4849
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0648 0.0648
Brugia malayi hypothetical protein 0.0071 0.066 0.1097
Brugia malayi hypothetical protein 0.0109 0.1118 0.1871
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0648 0.0796
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.0606 0.0744
Trypanosoma cruzi DNA polymerase eta, putative 0.0058 0.0506 0.4762
Loa Loa (eye worm) hypothetical protein 0.0508 0.5932 1
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0648 0.0648
Brugia malayi ImpB/MucB/SamB family protein 0.0058 0.0506 0.0838
Loa Loa (eye worm) hypothetical protein 0.0248 0.279 0.4693
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0175
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0081 0.0078
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.001 0.0008
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0122 0.1279 0.129
Onchocerca volvulus 0.0054 0.0451 0.0701
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0067 0.0606 0.061
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0176 0.0278
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0038 0.0035
Mycobacterium leprae Conserved hypothetical protein 0.0046 0.0355 0.2638
Echinococcus multilocularis G protein coupled receptor 139 0.0067 0.0606 0.061
Mycobacterium tuberculosis Probable oxidoreductase 0.0127 0.1337 0.1337
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0417 0.1557
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0046 0.0355 0.0355
Brugia malayi follicle stimulating hormone receptor 0.0296 0.3376 0.5684
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0083 0.0124
Schistosoma mansoni lamin 0.0054 0.0451 0.0553
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0566 0.0938
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0067 0.0606 0.0744
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0046 0.0355 0.0355
Brugia malayi beta-lactamase family protein 0.007 0.0648 0.1078
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0033 0.0203 0.0325
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0046 0.0355 0.0352
Echinococcus multilocularis thyroid hormone receptor alpha 0.0329 0.3774 0.3813
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0642 0.1065
Echinococcus granulosus peptide allatostatin:somatostatin 0.0067 0.0606 0.0744
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0261 0.0969
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.0606 0.0744
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0046 0.0355 0.0355
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0648 0.2426
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0051 0.0417 0.0511
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0176 0.1637
Brugia malayi Nuclear hormone receptor-like 1 0.0207 0.2295 0.3858
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0801 0.0984
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0207 0.2295 0.2318
Loa Loa (eye worm) RNA binding protein 0.0255 0.2882 0.4848
Brugia malayi latrophilin 2 splice variant baaae 0.0169 0.1844 0.3097
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0648 0.0648
Mycobacterium tuberculosis Conserved protein 0.007 0.0648 0.0648
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Echinococcus multilocularis dna polymerase kappa 0.006 0.0524 0.0526
Loa Loa (eye worm) hypothetical protein 0.0147 0.1572 0.2635
Plasmodium vivax flavodoxin domain containing protein 0.0026 0.0109 0.0949
Brugia malayi Cytochrome P450 family protein 0.0046 0.0355 0.0583
Schistosoma mansoni tar DNA-binding protein 0.0255 0.2882 0.3551
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0023 0.0083 0.008
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0634 0.0638
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0112 0.0173
Echinococcus granulosus neuropeptide receptor 0.0067 0.0606 0.0744
Echinococcus granulosus orexin receptor type 2 0.0067 0.0606 0.0744
Onchocerca volvulus 0.0147 0.1572 0.2602
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.1052 1
Brugia malayi Steroid receptor seven-up type 2 0.0207 0.2295 0.3858
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0406 0.0497
Schistosoma mansoni alpha-1 adrenergic receptor 0.0067 0.0606 0.0744
Schistosoma mansoni amine GPCR 0.0067 0.0606 0.0744
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0046 0.0355 0.0352
Brugia malayi hypothetical protein 0.0026 0.0112 0.0173
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0097 0.0977 0.0985
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0067 0.0606 0.0964
Schistosoma mansoni nuclear hormone receptor 0.0097 0.0977 0.1201
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0001
Onchocerca volvulus 0.0067 0.0606 0.0964
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0648 0.0645
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0046 0.0355 0.3313
Onchocerca volvulus Peroxidase homolog 0.0026 0.0112 0.0126
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.0606 0.0744
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.001 0.0008
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.0606 0.0744
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0597 0.0992
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0018 0.0015 0.0015
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0046 0.0355 0.0355
Schistosoma mansoni hypothetical protein 0.0071 0.066 0.081
Schistosoma mansoni hypothetical protein 0.0047 0.0372 0.0454
Brugia malayi FAD binding domain containing protein 0.0029 0.0148 0.0234
Echinococcus granulosus dna polymerase kappa 0.006 0.0524 0.0642
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0038 0.0261 0.0258
Echinococcus multilocularis GPCR, family 2 0.0078 0.0746 0.0751
Loa Loa (eye worm) hypothetical protein 0.0109 0.1118 0.1869
Echinococcus granulosus neuropeptide receptor A26 0.0067 0.0606 0.0744
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.1052 1
Brugia malayi Thioredoxin reductase 0.005 0.0406 0.0669
Echinococcus granulosus g protein coupled receptor 0.0067 0.0606 0.0744
Brugia malayi Dopamine receptor 0.0067 0.0606 0.1007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0248 0.279 0.4694
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0207 0.2295 0.2318
Brugia malayi Carboxylesterase family protein 0.0069 0.0634 0.1054
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0067 0.0606 0.1005
Schistosoma mansoni hypothetical protein 0.0046 0.0361 0.0442
Loa Loa (eye worm) hypothetical protein 0.0078 0.0746 0.1241
Onchocerca volvulus 0.0067 0.0606 0.0964
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Trypanosoma brucei cytochrome P450, putative 0.0063 0.0566 0.5342
Echinococcus granulosus tar DNA binding protein 0.0255 0.2882 0.3551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Echinococcus granulosus allatostatin A receptor 0.0067 0.0606 0.0744
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0051 0.0417 0.391
Trypanosoma brucei trypanothione reductase 0.005 0.0406 0.3803
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0648 0.1078
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Echinococcus multilocularis RUN 0.002 0.0038 0.0035
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0451 0.0743
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0067 0.0606 0.1007
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Onchocerca volvulus 0.0047 0.0372 0.0566
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0207 0.2295 0.3858
Trichomonas vaginalis CMGC family protein kinase 0.0051 0.0417 0.1557
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0175
Plasmodium falciparum nitric oxide synthase, putative 0.0029 0.0148 0.1329
Echinococcus multilocularis neuropeptide Y receptor 0.0067 0.0606 0.061
Schistosoma mansoni hypothetical protein 0.0078 0.0746 0.0916
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0046 0.0355 0.0355
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0207 0.2295 0.3858
Echinococcus multilocularis geminin 0.0669 0.7883 0.797
Brugia malayi intracellular kinase 0.0051 0.0417 0.0688
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0067 0.0606 0.1005
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0296 0.3376 0.5683
Echinococcus granulosus acetylcholinesterase 0.0069 0.0634 0.0778
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0038 0.027
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.1183 0.1183
Plasmodium vivax SET domain protein, putative 0.003 0.0161 0.1445
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0597 0.0601
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0451 0.0743
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0525 0.0522
Leishmania major DNA polymerase kappa, putative 0.004 0.0283 0.262
Loa Loa (eye worm) hypothetical protein 0.0109 0.1118 0.1869
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0067 0.0606 0.061
Loa Loa (eye worm) neuropeptide F receptor 0.0067 0.0606 0.1005
Trichomonas vaginalis set domain proteins, putative 0.0237 0.2662 1
Echinococcus multilocularis nuclear receptor nhr 48 0.0097 0.0977 0.0985
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0046 0.0355 0.0352
Echinococcus granulosus neuropeptide Y receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0176 0.0175
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.2051 0.2526
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0046 0.0355 0.0352
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0069 0.0634 0.0778
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0023 0.0083 0.0083
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.001 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0207 0.2295 0.2827
Loa Loa (eye worm) carboxylesterase 0.0069 0.0634 0.1052
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0648 0.2426
Loa Loa (eye worm) hypothetical protein 0.0026 0.0114 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0046 0.0355 0.0355
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0067 0.0606 0.061
Schistosoma mansoni DNA polymerase eta 0.0058 0.0506 0.062
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0245 0.226
Echinococcus multilocularis g-protein coupled receptor 0.0067 0.0606 0.061
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0097 0.0977 0.1201
Schistosoma mansoni thyroid hormone receptor 0.0329 0.3774 0.4651
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0067 0.0606 0.0744
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0176 0.1594
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0406 0.0407
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0112 0.017
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0081 0.0078
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.1225 0.1235
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Brugia malayi hypothetical protein 0.0232 0.2603 0.4378
Schistosoma mansoni biogenic amine receptor 0.0067 0.0606 0.0744
Onchocerca volvulus 0.0022 0.007 0.0053
Schistosoma mansoni survival motor neuron protein 0.0047 0.0372 0.0454
Plasmodium falciparum ataxin-2 like protein, putative 0.0104 0.1052 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0525 0.4948
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.0606 0.0744
Treponema pallidum NADH oxidase 0.0017 0.001 0.0259
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0207 0.2295 0.2318
Brugia malayi flavodoxin family protein 0.0029 0.0148 0.0234
Leishmania major DNA polymerase eta, putative 0.0058 0.0506 0.4762
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Schistosoma mansoni ap endonuclease 0.0038 0.0261 0.0318
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.001 0.0051
Brugia malayi nuclear receptor RXR 0.0109 0.1118 0.1871
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0176 0.0213
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0038 0.0261 1
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0801 0.0984
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0046 0.0355 0.0355
Trichomonas vaginalis esterase, putative 0.007 0.0648 0.2426
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0067 0.0606 0.1007
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0033 0.0203 0.0247
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0525 0.0644
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0746 0.0916
Schistosoma mansoni neuropeptide F-like receptor 0.0067 0.0606 0.0744
Entamoeba histolytica protein kinase, putative 0.0051 0.0417 0.5808
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0067 0.0606 0.061
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.066 0.081
Echinococcus multilocularis ecdysone induced protein 78C 0.0207 0.2295 0.2318
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.0606 0.061
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0597 0.8925
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0029 0.0148 0.1329
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0112 0.0173
Onchocerca volvulus 0.0067 0.0606 0.0964
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0149 0.0235
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0046 0.0355 0.0355
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0207 0.2295 0.3856
Leishmania major hypothetical protein, conserved 0.007 0.0648 0.6127
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Echinococcus granulosus neuropeptide s receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Mycobacterium leprae conserved hypothetical protein 0.007 0.0648 0.4835
Schistosoma mansoni coup transcription factor 0.0207 0.2295 0.2827
Schistosoma mansoni hypothetical protein 0.0169 0.1844 0.2271
Brugia malayi hypothetical protein 0.0104 0.1052 0.1759
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0067 0.0606 0.061
Trichomonas vaginalis ap endonuclease, putative 0.0038 0.0261 0.0969
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0046 0.0355 0.0355
Loa Loa (eye worm) cytochrome P450 0.0046 0.0355 0.0581
Loa Loa (eye worm) FAD binding domain-containing protein 0.0029 0.0148 0.0232
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0046 0.0355 0.0352
Schistosoma mansoni neuropeptide receptor 0.0067 0.0606 0.0744
Schistosoma mansoni retinoic acid receptor RXR 0.0567 0.665 0.8199
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0067 0.0606 0.061
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0525 0.4974
Echinococcus granulosus Nuclear hormone receptor HR96 0.0097 0.0977 0.1201
Schistosoma mansoni chromobox protein 0.007 0.0642 0.0787
Echinococcus granulosus dna polymerase eta 0.0058 0.0506 0.062
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0097 0.0977 0.1632
Brugia malayi beta-lactamase 0.007 0.0648 0.1078
Toxoplasma gondii cytochrome p450 superfamily protein 0.0046 0.0355 0.3347
Echinococcus multilocularis dro:myosuppressin receptor 0.0067 0.0606 0.061
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Loa Loa (eye worm) hypothetical protein 0.0023 0.0083 0.0121
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0406 0.3803
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0097 0.0977 0.0985
Loa Loa (eye worm) beta-lactamase 0.007 0.0648 0.1076
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0023 0.0083 0.0599
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.2051 0.2071
Loa Loa (eye worm) hypothetical protein 0.0053 0.044 0.0723
Brugia malayi chromobox protein homolog 3 0.0039 0.0272 0.0442
Schistosoma mansoni nuclear hormone receptor 0.0097 0.0977 0.1201
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0083 0.0703
Schistosoma mansoni steroid hormone receptor ad4bp 0.0207 0.2295 0.2827
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.0606 0.0744
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0648 0.2426
Onchocerca volvulus 0.0067 0.0606 0.0964
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Toxoplasma gondii thioredoxin reductase 0.005 0.0406 0.3835
Schistosoma mansoni biogenic amine (5HT) receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0835 0.989 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0038 0.0261 0.0422
Echinococcus multilocularis rhodopsin orphan GPCR 0.0067 0.0606 0.061
Brugia malayi neuropeptide F receptor 0.0067 0.0606 0.1007
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0112 0.017
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0207 0.2295 0.2827
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0524 0.4931
Echinococcus multilocularis FTZ F1 alpha 0.0207 0.2295 0.2318
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.2051 0.3445
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0648 0.0796
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0161 0.0159
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0112 0.0126
Loa Loa (eye worm) hypothetical protein 0.0069 0.0634 0.1052
Schistosoma mansoni terminal deoxycytidyl transferase 0.0033 0.0203 0.0247
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0406 0.3803
Loa Loa (eye worm) hypothetical protein 0.007 0.0648 0.1076
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0406 0.0406
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0648 0.0796
Schistosoma mansoni hypothetical protein 0.0122 0.1279 0.1574
Schistosoma mansoni biogenic amine receptor 0.0067 0.0606 0.0744
Mycobacterium ulcerans short chain dehydrogenase 0.0844 1 1
Schistosoma mansoni zinc finger protein 0.0097 0.0977 0.1201
Echinococcus multilocularis neuropeptide receptor 0.0067 0.0606 0.061
Schistosoma mansoni lipoxygenase 0.0082 0.0796 0.0978
Onchocerca volvulus 0.0026 0.0112 0.0126
Echinococcus granulosus RUN 0.002 0.0038 0.0043
Mycobacterium ulcerans hypothetical protein 0.007 0.0648 0.0645
Schistosoma mansoni hypothetical protein 0.0078 0.0746 0.0916
Schistosoma mansoni hypothetical protein 0.0046 0.0355 0.0434
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0067 0.0606 0.061
Schistosoma mansoni tar DNA-binding protein 0.0255 0.2882 0.3551
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Echinococcus granulosus alpha 1A adrenergic receptor 0.0067 0.0606 0.0744
Brugia malayi Nuclear hormone receptor E75 0.0097 0.0977 0.1632
Echinococcus multilocularis fmrfamide receptor 0.0067 0.0606 0.061
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0525 0.0528
Echinococcus granulosus tm gpcr rhodopsin 0.0067 0.0606 0.0744
Echinococcus multilocularis tar DNA binding protein 0.0255 0.2882 0.2911
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0012 0.0015
Entamoeba histolytica acyl-coA synthetase, putative 0.0023 0.0083 0.003
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0023 0.0083 0.008
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) transcription factor SMAD2 0.0127 0.133 0.2228
Mycobacterium ulcerans DNA polymerase IV 0.006 0.0524 0.0521
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0207 0.2295 0.2827
Schistosoma mansoni neuropeptide receptor 0.0067 0.0606 0.0744
Schistosoma mansoni amine GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Onchocerca volvulus 0.0067 0.0606 0.0964
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0207 0.2295 0.3858
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0051 0.0417 0.0511
Loa Loa (eye worm) hypothetical protein 0.0169 0.1844 0.3095
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0176 0.1594
Echinococcus multilocularis peroxidasin 0.0026 0.0112 0.011
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.001 0.0051
Mycobacterium leprae Probable lipase LipE 0.007 0.0648 0.4835
Schistosoma mansoni hypothetical protein 0.0103 0.1049 0.1291
Trypanosoma cruzi PAB1-binding protein , putative 0.0104 0.1052 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0067 0.0606 0.1005
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Trypanosoma brucei PAB1-binding protein , putative 0.0104 0.1052 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0109 0.1118 0.1375
Giardia lamblia DINP protein human, muc B family 0.004 0.0283 0.6701
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0567 0.665 0.8199
Giardia lamblia Hypothetical protein 0.0026 0.0109 0.2427
Echinococcus granulosus tachykinin peptides receptor 99D 0.0067 0.0606 0.0744
Treponema pallidum exodeoxyribonuclease (exoA) 0.0038 0.0261 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0207 0.2295 0.2827
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0406 0.0667
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0109 0.1118 0.1375
Brugia malayi Nuclear hormone receptor E75 0.0097 0.0977 0.1632
Onchocerca volvulus Bile acid receptor homolog 0.0508 0.5932 1
Loa Loa (eye worm) glutathione reductase 0.005 0.0406 0.0667
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0207 0.2295 0.3858
Brugia malayi tailless protein 0.0097 0.0977 0.1632
Schistosoma mansoni hypothetical protein 0.0669 0.7883 0.9721
Schistosoma mansoni RAR-like nuclear receptor 0.0207 0.2295 0.2827
Onchocerca volvulus 0.0041 0.0298 0.0441
Brugia malayi Peroxidasin 0.0026 0.0112 0.0173
Loa Loa (eye worm) hypothetical protein 0.0207 0.2295 0.3856
Schistosoma mansoni histamine h1 receptor 0.0067 0.0606 0.0744
Loa Loa (eye worm) hypothetical protein 0.0109 0.1118 0.1869
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.001 0.0007
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0207 0.2295 0.2827
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0451 0.0745
Brugia malayi Serotonin receptor 0.0067 0.0606 0.1007
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0648 0.6127
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0648 0.0648
Brugia malayi Cytochrome P450 family protein 0.0063 0.0566 0.094
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0158 0.1418
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0083 0.0124
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.1183 0.8843
Leishmania major cytochrome P450 reductase, putative 0.0026 0.0109 0.0949
Leishmania major cytochrome p450-like protein 0.0046 0.0355 0.3313
Echinococcus granulosus ecdysone induced protein 78C 0.0207 0.2295 0.2827
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.066 0.081
Entamoeba histolytica deoxycytidyl transferase, putative 0.0033 0.0203 0.211
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0207 0.2295 0.3858
Loa Loa (eye worm) hypothetical protein 0.0232 0.2603 0.4377
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0283 0.262
Echinococcus granulosus GA binding protein alpha chain 0.0071 0.0658 0.0808
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0067 0.0606 0.0744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0207 0.2295 0.3856
Loa Loa (eye worm) hypothetical protein 0.007 0.0648 0.1076
Trypanosoma cruzi cytochrome P450, putative 0.0063 0.0566 0.5342
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0801 0.1336
Loa Loa (eye worm) hypothetical protein 0.0097 0.0977 0.163
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0046 0.0355 0.0352
Brugia malayi Cytochrome P450 family protein 0.0063 0.0566 0.094
Echinococcus multilocularis methionine synthase reductase 0.0018 0.0015 0.0012
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0648 0.0648
Brugia malayi hypothetical protein 0.0067 0.0606 0.1007
Echinococcus multilocularis chromobox protein 1 0.007 0.0642 0.0646
Entamoeba histolytica acyl-CoA synthetase, putative 0.0023 0.0083 0.003
Brugia malayi Ets-domain containing protein 0.0071 0.0658 0.1095
Echinococcus multilocularis neuropeptide FF receptor 2 0.0067 0.0606 0.061
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Plasmodium falciparum glycogen synthase kinase 3 0.0051 0.0417 0.391
Echinococcus multilocularis acetylcholinesterase 0.0069 0.0634 0.0638
Trypanosoma brucei protein kinase, putative 0.0051 0.0417 0.391
Leishmania major 4-coumarate:coa ligase-like protein 0.0023 0.0083 0.0703
Echinococcus granulosus rhodopsin orphan GPCR 0.0067 0.0606 0.0744
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.2051 0.2526
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0026 0.0112 0.017
Trypanosoma brucei DNA polymerase IV, putative 0.006 0.0524 0.4931
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0176 0.1594
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0158 0.1418
Echinococcus multilocularis neuropeptide s receptor 0.0067 0.0606 0.061
Loa Loa (eye worm) nuclear receptor NHR-67 0.0097 0.0977 0.163
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0038 0.0261 0.0261
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0067 0.0606 0.0744
Onchocerca volvulus 0.0067 0.0606 0.0964
Loa Loa (eye worm) hypothetical protein 0.0067 0.0606 0.1005
Brugia malayi ecdysone receptor 0.0097 0.0977 0.1632
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0067 0.0606 0.061
Loa Loa (eye worm) hypothetical protein 0.0061 0.0534 0.0882
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0063 0.0566 0.0563
Loa Loa (eye worm) hypothetical protein 0.0018 0.0012 0.0001
Echinococcus multilocularis GA binding protein alpha chain 0.0071 0.0658 0.0662
Echinococcus granulosus thyroid hormone receptor alpha 0.0097 0.0977 0.1201
Brugia malayi beta-lactamase family protein 0.007 0.0648 0.1078
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0208 0.2314 0.3889
Brugia malayi Dopamine receptor protein 1 0.0067 0.0606 0.1007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0127 0.1337 0.1337
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0525 0.0525
Trypanosoma brucei DNA polymerase kappa, putative 0.006 0.0524 0.4931
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.001 0.0007
Echinococcus granulosus biogenic amine 5HT receptor 0.0067 0.0606 0.0744
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0458 0.5332 0.539
Mycobacterium tuberculosis Conserved protein 0.007 0.0648 0.0648
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0081 0.0586

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 108 nM Tested for concentration of ligand causing half maximal response of Calcium ion release from permeabilised hepatocytes ChEMBL. 11063623
Ki (functional) = 2.19 nM Tested for equilibrium competition binding to InsP3 receptor in hepatic membranes using 1.3-1.8 nM [3H]Ins(1,4,5)P3 as the radioligand. ChEMBL. 11063623
Max response (functional) = 57 % Tested for percentage of intracellular calcium ion stores released in rat hepatocytes ChEMBL. 11063623

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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