Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | uridine phosphorylase 1 | 0.0191 | 0.1264 | 0.1671 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.2576 |
Trypanosoma cruzi | arginine N-methyltransferase, type III | 0.0028 | 0.0046 | 0.0026 |
Loa Loa (eye worm) | PWWP domain-containing protein | 0.0026 | 0.0026 | 0.0028 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.2576 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0026 | 0.0028 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0191 | 0.1264 | 0.1224 |
Echinococcus granulosus | geminin | 0.0168 | 0.1085 | 0.1435 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0048 | 0.0047 |
Schistosoma mansoni | enhancer of zeste ezh | 0.0196 | 0.1301 | 0.172 |
Loa Loa (eye worm) | NNMT/PNMT/TEMT family protein | 0.0889 | 0.6478 | 0.7083 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0048 | 0.0064 |
Loa Loa (eye worm) | Carm1-pending protein | 0.0144 | 0.0908 | 0.0993 |
Trypanosoma cruzi | protein arginine n-methyltransferase 7 | 0.0028 | 0.0046 | 0.0026 |
Loa Loa (eye worm) | hypothetical protein | 0.0889 | 0.6478 | 0.7083 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.003 | 0.006 | 0.0079 |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.0191 | 0.1264 | 0.1264 |
Echinococcus multilocularis | protein arginine N methyltransferase 8 | 0.003 | 0.006 | 0.0079 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0059 | 0.0273 | 0.0327 |
Brugia malayi | Protein arginine N-methyltransferase | 0.0028 | 0.0046 | 0.005 |
Toxoplasma gondii | S-Adenosyl homocysteine hydrolase | 0.0669 | 0.4832 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0191 | 0.1264 | 0.1224 |
Echinococcus granulosus | protein arginine N methyltransferase 8 | 0.003 | 0.006 | 0.0079 |
Schistosoma mansoni | uridine phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Loa Loa (eye worm) | hypothetical protein | 0.0128 | 0.0787 | 0.086 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Loa Loa (eye worm) | protein arginine N-methyltransferase | 0.0028 | 0.0046 | 0.005 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0669 | 0.4832 | 0.6377 |
Trypanosoma cruzi | arginine N-methyltransferase, type I | 0.0028 | 0.0046 | 0.0026 |
Echinococcus multilocularis | histone lysine n methyltransferase suv420h1 | 0.0133 | 0.083 | 0.1098 |
Mycobacterium ulcerans | 5'-methylthioadenosine phosphorylase | 0.1034 | 0.7563 | 1 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1643 |
Toxoplasma gondii | hypothetical protein | 0.0172 | 0.1116 | 0.2268 |
Echinococcus multilocularis | cpg binding protein | 0.0098 | 0.0567 | 0.0749 |
Schistosoma mansoni | phd finger protein | 0.0026 | 0.0026 | 0.0034 |
Trypanosoma brucei | spermidine synthase | 0.0695 | 0.503 | 0.6639 |
Leishmania major | arginine N-methyltransferase, type III, putative;with=GeneDB:Tb927.7.5490 | 0.0028 | 0.0046 | 0.0026 |
Echinococcus multilocularis | disco interacting protein 2 | 0.0078 | 0.0417 | 0.0551 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0027 | 0.0035 | 0.0046 |
Toxoplasma gondii | phosphorylase family protein | 0.0191 | 0.1264 | 0.2576 |
Toxoplasma gondii | histone arginine methyltransferase PRMT4/CARM1 | 0.0144 | 0.0908 | 0.1835 |
Echinococcus multilocularis | hepatoma derived growth factor protein | 0.0026 | 0.0026 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0629 | 0.0688 |
Plasmodium vivax | spermidine synthase, putative | 0.0695 | 0.503 | 1 |
Chlamydia trachomatis | AMP nucleosidase | 0.0191 | 0.1264 | 0.5 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0025 | 0.0023 | 0.003 |
Onchocerca volvulus | 0.0026 | 0.0026 | 0.0026 | |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0025 | 0.0023 | 0.003 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1085 | 0.1435 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.003 | 0.006 | 0.0014 |
Entamoeba histolytica | hypothetical protein | 0.0191 | 0.1264 | 0.2576 |
Loa Loa (eye worm) | spermidine synthase | 0.0695 | 0.503 | 0.5499 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0687 | 0.4964 | 0.6564 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0048 | 0.0053 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Onchocerca volvulus | 0.0231 | 0.156 | 0.156 | |
Schistosoma mansoni | hepatoma derived growth factor | 0.0026 | 0.0026 | 0.0034 |
Schistosoma mansoni | histone J3 methyltransferase | 0.0128 | 0.0787 | 0.104 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0025 | 0.0023 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.156 | 0.1706 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Schistosoma mansoni | jumonji domain containing protein | 0.0075 | 0.0393 | 0.052 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0669 | 0.4832 | 0.5283 |
Echinococcus granulosus | DNA methyltransferase 2, putative | 0.012 | 0.0733 | 0.097 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.1246 | 0.9146 | 1 |
Toxoplasma gondii | C-5 cytosine-specific DNA methylase superfamily protein | 0.012 | 0.0733 | 0.1472 |
Echinococcus multilocularis | histone h3 methyltransferase | 0.0128 | 0.0787 | 0.104 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0191 | 0.1264 | 1 |
Toxoplasma gondii | bicoid-interacting protein BIN3 | 0.0028 | 0.0046 | 0.0041 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0414 | 0.2926 | 0.387 |
Brugia malayi | SET domain containing protein | 0.0196 | 0.1301 | 0.1423 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1085 | 0.1435 |
Plasmodium falciparum | protein arginine N-methyltransferase 1 | 0.003 | 0.006 | 0.0023 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0191 | 0.1264 | 1 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0094 | 0.0538 | 0.0712 |
Echinococcus granulosus | histone lysine N methyltransferase Ez | 0.0196 | 0.1301 | 0.172 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase | 0.0777 | 0.5642 | 0.7451 |
Echinococcus multilocularis | histone arginine methyltransferase CARMER | 0.0144 | 0.0908 | 0.12 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.0191 | 0.1264 | 0.1224 |
Trypanosoma cruzi | spermidine synthase, putative | 0.0695 | 0.503 | 0.6639 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0414 | 0.2926 | 0.387 |
Entamoeba histolytica | hypothetical protein | 0.0059 | 0.0273 | 0.0513 |
Trypanosoma cruzi | spermidine synthase, putative | 0.0695 | 0.503 | 0.6639 |
Trypanosoma cruzi | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0777 | 0.5642 | 0.7451 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0048 | 0.0064 |
Toxoplasma gondii | histone arginine methyltransferase PRMT1 | 0.003 | 0.006 | 0.007 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0106 | 0.014 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0185 | 0.1213 | 0.1604 |
Echinococcus multilocularis | PWWP domain containing protein 2A | 0.0026 | 0.0026 | 0.0034 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0048 | 0.0048 |
Plasmodium vivax | DNA (cytosine-5)-methyltransferase, putative | 0.012 | 0.0733 | 0.1375 |
Trypanosoma brucei | methylthioadenosine phosphorylase, putative | 0.1034 | 0.7563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.156 | 0.1706 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.003 | 0.006 | 0.0079 |
Treponema pallidum | uridine phosphorylase (udp) | 0.0191 | 0.1264 | 0.5 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.021 | 0.1402 | 0.1363 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.003 | 0.006 | 0.0014 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Schistosoma mansoni | cpg binding protein | 0.0097 | 0.0554 | 0.0733 |
Schistosoma mansoni | cpg binding protein | 0.0098 | 0.0567 | 0.0749 |
Echinococcus multilocularis | methylthioadenosine phosphorylase | 0.1034 | 0.7563 | 1 |
Brugia malayi | MTAP | 0.1034 | 0.7563 | 0.8269 |
Leishmania major | arginine N-methyltransferase-like protein | 0.003 | 0.006 | 0.0045 |
Trypanosoma cruzi | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0777 | 0.5642 | 0.7451 |
Leishmania major | nucleoside phosphorylase-like protein | 0.0191 | 0.1264 | 0.1643 |
Echinococcus multilocularis | DNA methyltransferase 2, putative | 0.012 | 0.0733 | 0.097 |
Onchocerca volvulus | 0.0232 | 0.157 | 0.157 | |
Echinococcus granulosus | histone lysine N methyltransferase H3 lysine 36 | 0.0037 | 0.0112 | 0.0148 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.0191 | 0.1264 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0027 | 0.0038 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0023 | 0.0025 |
Brugia malayi | Disco-interacting protein 2 homolog | 0.0078 | 0.0417 | 0.0456 |
Echinococcus multilocularis | PWWP domain containing protein 2A | 0.0026 | 0.0026 | 0.0034 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.1034 | 0.7563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0417 | 0.0456 |
Echinococcus granulosus | SET and MYND domain containing protein 3 | 0.007 | 0.0355 | 0.0469 |
Plasmodium vivax | protein arginine N-methyltransferase 1, putative | 0.003 | 0.006 | 0.0023 |
Echinococcus granulosus | histone arginine methyltransferase CARMER | 0.0144 | 0.0908 | 0.12 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0687 | 0.4964 | 0.6564 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0148 | 0.0937 | 0.1239 |
Brugia malayi | hypothetical protein | 0.0231 | 0.156 | 0.1706 |
Leishmania major | spermidine synthase | 0.0695 | 0.503 | 0.6639 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0106 | 0.014 |
Brugia malayi | PWWP domain containing protein | 0.0026 | 0.0026 | 0.0028 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0025 | 0.0023 | 0.003 |
Mycobacterium ulcerans | spermidine synthase | 0.0557 | 0.3993 | 0.4333 |
Echinococcus granulosus | cpg binding protein | 0.0098 | 0.0567 | 0.0749 |
Brugia malayi | Bromodomain containing protein | 0.0027 | 0.0035 | 0.0038 |
Plasmodium vivax | S-adenosylmethionine decarboxylase-ornithine decarboxylase, putative | 0.0379 | 0.2662 | 0.5248 |
Echinococcus multilocularis | histone lysine N methyltransferase E(z) | 0.0196 | 0.1301 | 0.172 |
Trypanosoma cruzi | S-adenosylhomocysteine hydrolase, putative | 0.0669 | 0.4832 | 0.6377 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0106 | 0.0116 |
Entamoeba histolytica | MTA/SAH nucleosidase, putative | 0.0191 | 0.1264 | 0.2576 |
Loa Loa (eye worm) | S-adenosylmethionine decarboxylase proenzyme | 0.0777 | 0.5642 | 0.6169 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0106 | 0.014 |
Loa Loa (eye worm) | SET domain-containing protein | 0.0196 | 0.1301 | 0.1423 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase | 0.0777 | 0.5642 | 0.7451 |
Brugia malayi | Pre-SET motif family protein | 0.1246 | 0.9146 | 1 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.1034 | 0.7563 | 1 |
Echinococcus multilocularis | protein arginine N methyltransferase 7 | 0.0028 | 0.0046 | 0.006 |
Loa Loa (eye worm) | S-methyl-5'-thioadenosine phosphorylase MTAP | 0.1034 | 0.7563 | 0.8269 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0026 | 0.0028 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.1034 | 0.7563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0889 | 0.6478 | 0.7083 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0414 | 0.2926 | 0.387 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1643 |
Echinococcus granulosus | peregrin | 0.0055 | 0.0241 | 0.0319 |
Plasmodium falciparum | spermidine synthase | 0.0695 | 0.503 | 1 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0669 | 0.4832 | 0.5665 |
Treponema pallidum | pfs protein (pfs) | 0.0191 | 0.1264 | 0.5 |
Leishmania major | methylthioadenosine phosphorylase, putative | 0.1034 | 0.7563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0273 | 0.0298 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Echinococcus granulosus | histone lysine n methyltransferase setb1 | 0.0033 | 0.0083 | 0.011 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Plasmodium vivax | SET domain protein, putative | 0.0126 | 0.0773 | 0.1455 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0065 | 0.0319 | 0.061 |
Plasmodium falciparum | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.2441 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.1213 | 0.1327 |
Trypanosoma cruzi | spermidine synthase, putative | 0.0695 | 0.503 | 0.6639 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0083 | 0.0091 |
Plasmodium vivax | adenosylhomocysteinase(S-adenosyl-L-homocystein e hydrolase), putative | 0.0669 | 0.4832 | 0.9604 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Trichomonas vaginalis | set domain proteins, putative | 0.136 | 1 | 1 |
Brugia malayi | purine nucleoside phosphorylase I, inosine and guanosine-specific family protein | 0.0191 | 0.1264 | 0.1382 |
Brugia malayi | SET domain containing protein | 0.0118 | 0.0716 | 0.0783 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.156 | 0.1706 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0126 | 0.0773 | 0.1022 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0414 | 0.2926 | 0.387 |
Mycobacterium tuberculosis | Probable spermidine synthase SpeE (putrescine aminopropyltransferase) (aminopropyltransferase) (SPDSY) | 0.0557 | 0.3993 | 0.5607 |
Leishmania major | S-adenosylhomocysteine hydrolase | 0.0669 | 0.4832 | 0.6377 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.0026 | 0.0034 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.0026 | 0.0034 |
Brugia malayi | CXXC zinc finger family protein | 0.0097 | 0.0554 | 0.0606 |
Trichomonas vaginalis | protein arginine N-methyltransferase, putative | 0.003 | 0.006 | 0.0014 |
Echinococcus multilocularis | SET and MYND domain containing protein 3 | 0.007 | 0.0355 | 0.0469 |
Onchocerca volvulus | 0.0026 | 0.0026 | 0.0026 | |
Schistosoma mansoni | uridine phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Echinococcus granulosus | spermidine synthase | 0.0695 | 0.503 | 0.665 |
Echinococcus granulosus | PWWP domain containing protein 2A | 0.0026 | 0.0026 | 0.0034 |
Schistosoma mansoni | suppressor of variegation 4-20-related | 0.0133 | 0.083 | 0.1098 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0278 | 0.0304 |
Schistosoma mansoni | DNA (cytosine-5)-methyltransferase | 0.012 | 0.0733 | 0.097 |
Brugia malayi | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 0.0128 | 0.0787 | 0.086 |
Plasmodium falciparum | histone-lysine N-methyltransferase, putative | 0.0081 | 0.0441 | 0.0789 |
Leishmania major | modification methylase-like protein | 0.012 | 0.0733 | 0.0939 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0027 | 0.0035 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0026 | 0.0028 |
Echinococcus multilocularis | S adenosylmethionine decarboxylase proenzyme | 0.0777 | 0.5642 | 0.746 |
Schistosoma mansoni | hypothetical protein | 0.0026 | 0.0026 | 0.0034 |
Loa Loa (eye worm) | uridine phosphorylase | 0.0191 | 0.1264 | 0.1382 |
Entamoeba histolytica | arginine N-methyltransferase protein, putative | 0.0059 | 0.0273 | 0.0513 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0106 | 0.0116 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Echinococcus multilocularis | spermidine synthase | 0.0695 | 0.503 | 0.665 |
Trypanosoma cruzi | arginine N-methyltransferase, putative | 0.0059 | 0.0273 | 0.0327 |
Toxoplasma gondii | adenosylhomocysteinase, putative | 0.0669 | 0.4832 | 1 |
Echinococcus multilocularis | protein arginine methyltransferase | 0.003 | 0.006 | 0.0079 |
Echinococcus granulosus | histone lysine n methyltransferase suv420h1 | 0.0133 | 0.083 | 0.1098 |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0669 | 0.4832 | 0.6389 |
Echinococcus multilocularis | uridine phosphorylase 1 | 0.0191 | 0.1264 | 0.1671 |
Schistosoma mansoni | cpg binding protein | 0.0098 | 0.0567 | 0.0749 |
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.0191 | 0.1264 | 0.5 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1643 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0094 | 0.0124 |
Toxoplasma gondii | histone arginine methyltransferase PRMT3 | 0.0028 | 0.0046 | 0.0041 |
Echinococcus granulosus | disco interacting protein 2 | 0.0078 | 0.0417 | 0.0551 |
Brugia malayi | NNMT/PNMT/TEMT family protein | 0.0889 | 0.6478 | 0.7083 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0652 | 0.0713 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0097 | 0.0554 | 0.0606 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Trypanosoma brucei | S-adenosylmethionine decarboxylase proenzyme, putative | 0.0777 | 0.5642 | 0.7451 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.0133 | 0.0175 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0669 | 0.4832 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0669 | 0.4832 | 0.6389 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0687 | 0.4964 | 0.6564 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Echinococcus granulosus | hepatoma derived growth factor protein | 0.0026 | 0.0026 | 0.0034 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Brugia malayi | S-adenosylmethionine decarboxylase proenzyme | 0.0777 | 0.5642 | 0.6169 |
Entamoeba histolytica | arginine N-methyltransferase 1, putative | 0.0028 | 0.0046 | 0.0041 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0048 | 0.0053 |
Trypanosoma brucei | Protein arginine N-methyltransferase 1 catalytic subunit | 0.0059 | 0.0273 | 0.0327 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.2576 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0669 | 0.4832 | 0.4808 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.0133 | 0.0175 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0126 | 0.0773 | 0.1555 |
Schistosoma mansoni | disco-interacting protein 2 (dip2) | 0.0078 | 0.0417 | 0.0551 |
Echinococcus granulosus | methyltransferase protein 5 | 0.0028 | 0.0046 | 0.006 |
Trypanosoma brucei | cytosine-specific DNA methylase, putative | 0.012 | 0.0733 | 0.0939 |
Onchocerca volvulus | 0.0078 | 0.0417 | 0.0417 | |
Toxoplasma gondii | DNA methyltransferase 2, putative | 0.012 | 0.0733 | 0.1472 |
Plasmodium vivax | histone-lysine N-methyltransferase, putative | 0.0081 | 0.0441 | 0.0789 |
Schistosoma mansoni | hepatoma derived growth factor | 0.0026 | 0.0026 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0341 | 0.0373 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0094 | 0.0538 | 0.0712 |
Loa Loa (eye worm) | SET domain-containing protein | 0.0133 | 0.083 | 0.0908 |
Brugia malayi | jmjC domain containing protein | 0.0094 | 0.0538 | 0.0589 |
Trypanosoma cruzi | arginine N-methyltransferase, type I | 0.0028 | 0.0046 | 0.0026 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Plasmodium vivax | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.2441 |
Schistosoma mansoni | protein arginine N-methyltransferase 1 | 0.003 | 0.006 | 0.0079 |
Giardia lamblia | UPL-1 | 0.0191 | 0.1264 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0669 | 0.4832 | 0.733 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0172 | 0.1116 | 0.2143 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.2576 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0048 | 0.0053 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0048 | 0.0064 |
Echinococcus granulosus | S adenosylmethionine decarboxylase proenzyme | 0.0777 | 0.5642 | 0.746 |
Plasmodium falciparum | adenosylhomocysteinase | 0.0669 | 0.4832 | 0.9604 |
Echinococcus granulosus | protein arginine methyltransferase | 0.003 | 0.006 | 0.0079 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0072 | 0.0367 | 0.0486 |
Echinococcus multilocularis | histone lysine N methyltransferase, H3 lysine 36 | 0.0037 | 0.0112 | 0.0148 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0232 | 0.157 | 0.2075 |
Echinococcus granulosus | PWWP domain containing protein 2A | 0.0026 | 0.0026 | 0.0034 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0048 | 0.0047 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0126 | 0.0773 | 0.1022 |
Schistosoma mansoni | protein arginine n-methyltransferase | 0.0144 | 0.0908 | 0.12 |
Echinococcus multilocularis | peregrin | 0.0055 | 0.0241 | 0.0319 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.1034 | 0.7563 | 1 |
Echinococcus granulosus | methylthioadenosine phosphorylase | 0.1034 | 0.7563 | 1 |
Onchocerca volvulus | 0.0097 | 0.0554 | 0.0554 | |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.2576 |
Trypanosoma brucei | uridine phosphorylase | 0.0191 | 0.1264 | 0.1643 |
Leishmania major | arginine N-methyltransferase, type I | 0.0028 | 0.0046 | 0.0026 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0048 | 0.0064 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Trypanosoma brucei | S-adenosylhomocysteine hydrolase, putative | 0.0669 | 0.4832 | 0.6377 |
Brugia malayi | SET domain containing protein | 0.0133 | 0.083 | 0.0908 |
Onchocerca volvulus | 0.0115 | 0.0695 | 0.0695 | |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0202 | 0.0221 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0029 | 0.005 | 0.0055 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.0217 | 0.0287 |
Brugia malayi | Pre-SET motif family protein | 0.0159 | 0.1023 | 0.1119 |
Trichomonas vaginalis | purine nucleoside phosphorylase, putative | 0.0191 | 0.1264 | 0.1224 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0185 | 0.1213 | 0.1604 |
Toxoplasma gondii | phosphorylase family protein | 0.0191 | 0.1264 | 0.2576 |
Leishmania major | S-adenosylmethionine decarboxylase | 0.0777 | 0.5642 | 0.7451 |
Echinococcus granulosus | histone h3 methyltransferase | 0.0128 | 0.0787 | 0.104 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1085 | 0.1435 |
Schistosoma mansoni | SET domain protein | 0.0039 | 0.0124 | 0.0164 |
Plasmodium falciparum | DNA (cytosine-5)-methyltransferase | 0.012 | 0.0733 | 0.1375 |
Plasmodium falciparum | S-adenosylmethionine decarboxylase/ornithine decarboxylase | 0.0379 | 0.2662 | 0.5248 |
Trichomonas vaginalis | adenosylhomocysteinase, putative | 0.0669 | 0.4832 | 0.4808 |
Entamoeba histolytica | DNA (cytosine-5)-methyltransferase, putative | 0.012 | 0.0733 | 0.1472 |
Brugia malayi | hypothetical protein | 0.0231 | 0.156 | 0.1706 |
Mycobacterium tuberculosis | Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) | 0.0843 | 0.6132 | 1 |
Entamoeba histolytica | adenosylhomocysteinase, putative | 0.0669 | 0.4832 | 1 |
Brugia malayi | Spermidine synthase | 0.0695 | 0.503 | 0.5499 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0185 | 0.1213 | 0.1604 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0191 | 0.1264 | 0.1671 |
Brugia malayi | uridine phosphorylase family protein | 0.0191 | 0.1264 | 0.1382 |
Echinococcus multilocularis | histone lysine n methyltransferase setb1 | 0.0033 | 0.0083 | 0.011 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0185 | 0.1213 | 0.1604 |
Brugia malayi | hypothetical protein | 0.0059 | 0.0273 | 0.0298 |
Brugia malayi | Carm1-pending protein | 0.0144 | 0.0908 | 0.0993 |
Brugia malayi | Adenosylhomocysteinase | 0.0669 | 0.4832 | 0.5283 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0048 | 0.0053 |
Echinococcus granulosus | adenosylhomocysteinase | 0.0669 | 0.4832 | 0.6389 |
Trypanosoma cruzi | spermidine synthase, putative | 0.0695 | 0.503 | 0.6639 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.0046 | 0.006 |
Trypanosoma brucei | protein arginine n-methyltransferase 7 | 0.0028 | 0.0046 | 0.0026 |
Echinococcus granulosus | protein arginine N methyltransferase 7 | 0.0028 | 0.0046 | 0.006 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ca2+ reduction (functional) | = -7.9 | The compound was tested for oral delivery of calcitonin, activity is measured as reduction in serum calcium levels. | ChEMBL. | 7473553 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.