Detailed information for compound 234266

Basic information

Technical information
  • TDR Targets ID: 234266
  • Name: (2S)-6-[[2-(N-methylanilino)acetyl]amino]-2-[ (4-methylphenyl)sulfonyl-(2-methylpropyl)amin o]hexanoic acid
  • MW: 503.654 | Formula: C26H37N3O5S
  • H donors: 2 H acceptors: 5 LogP: 4.63 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(CN(S(=O)(=O)c1ccc(cc1)C)[C@H](C(=O)O)CCCCNC(=O)CN(c1ccccc1)C)C
  • InChi: 1S/C26H37N3O5S/c1-20(2)18-29(35(33,34)23-15-13-21(3)14-16-23)24(26(31)32)12-8-9-17-27-25(30)19-28(4)22-10-6-5-7-11-22/h5-7,10-11,13-16,20,24H,8-9,12,17-19H2,1-4H3,(H,27,30)(H,31,32)/t24-/m0/s1
  • InChiKey: CRRZARJNNKORLN-DEOSSOPVSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2S)-2-[isobutyl(p-tolylsulfonyl)amino]-6-[[2-(N-methylanilino)acetyl]amino]hexanoic acid
  • (2S)-2-[isobutyl(p-tolylsulfonyl)amino]-6-[[2-(N-methylanilino)-1-oxoethyl]amino]hexanoic acid
  • (2S)-6-[2-[methyl(phenyl)amino]ethanoylamino]-2-[(4-methylphenyl)sulfonyl-(2-methylpropyl)amino]hexanoic acid
  • (2S)-2-[isobutyl(tosyl)amino]-6-[[2-(N-methylanilino)acetyl]amino]hexanoic acid
  • (2S)-6-[[2-(methyl-phenylamino)acetyl]amino]-2-[(4-methylphenyl)sulfonyl-(2-methylpropyl)amino]hexanoic acid
  • (2S)-2-[isobutyl-(4-methylphenyl)sulfonyl-amino]-6-[[2-(methyl-phenyl-amino)acetyl]amino]hexanoic acid
  • (2S)-2-[isobutyl-(4-methylphenyl)sulfonylamino]-6-[[2-(methyl-phenylamino)-1-oxoethyl]amino]hexanoic acid
  • (2S)-6-[2-(methyl-phenyl-amino)ethanoylamino]-2-[(4-methylphenyl)sulfonyl-(2-methylpropyl)amino]hexanoic acid
  • AIDS-180181
  • AIDS180181
  • N.alpha.-isobutyl-N.alpha.-(4-methylbenzenesulfonyl)-N.epsilon.-(N'.alpha.-methyl-N'.alpha.-phenylglycyl]-L-lysine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Human immunodeficiency virus 1 Human immunodeficiency virus type 1 protease Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) Get druggable targets OG5_131408 All targets in OG5_131408
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei variant surface glycoprotein (VSG), putative Human immunodeficiency virus type 1 protease   99 aa 80 aa 27.5 %
Mycobacterium leprae Hypothetical protein Human immunodeficiency virus type 1 protease   99 aa 86 aa 27.9 %
Echinococcus multilocularis Chromobox protein 3 Human immunodeficiency virus type 1 protease   99 aa 95 aa 28.4 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Giardia lamblia DNA-directed RNA polymerase subunit D Human immunodeficiency virus type 1 protease   99 aa 90 aa 27.8 %
Candida albicans dethiobiotin synthetase Human immunodeficiency virus type 1 protease   99 aa 90 aa 22.2 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Entamoeba histolytica retroviral aspartyl protease domain-containing protein Human immunodeficiency virus type 1 protease   99 aa 103 aa 31.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Pre-SET motif family protein 0.0229 0.1234 0.234
Echinococcus multilocularis RUN 0.0043 0.0174 0.0174
Schistosoma mansoni geranylgeranyl pyrophosphate synthase 0.0028 0.0091 0.0105
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0404 0.7105
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Mycobacterium ulcerans oxidoreductase 0.0024 0.0068 0.0242
Brugia malayi neuropeptide F receptor 0.0055 0.024 0.0456
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Echinococcus multilocularis g protein coupled receptor 0.0055 0.024 0.024
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0019 0.004 0.0139
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0123 0.0145
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0225 0.1209 0.4334
Schistosoma mansoni opsin-like receptor 0.0055 0.024 0.0279
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0166 0.039
Echinococcus multilocularis dna polymerase eta 0.0021 0.0049 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0178 0.042
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.002 0.0023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0125 0.0642 0.2299
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0174 0.0204
Trichomonas vaginalis Ferredoxin 3 0.0024 0.0068 0.0161
Mycobacterium tuberculosis Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) 0.0028 0.0091 0.0457
Schistosoma mansoni hypothetical protein 0.0055 0.024 0.0279
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.024 0.024
Mycobacterium leprae conserved hypothetical protein 0.0022 0.0054 0.0402
Schistosoma mansoni hypothetical protein 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0341 0.0736
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.019
Schistosoma mansoni nuclear hormone receptor 0.094 0.5274 0.612
Echinococcus multilocularis tyrosine protein kinase HCK 0.0033 0.0118 0.0118
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0017 0.0025 0.0029
Plasmodium falciparum ubiquitin-conjugating enzyme E2 N, putative 0.0042 0.0166 0.2912
Brugia malayi Nuclear hormone receptor E75 0.0443 0.245 0.4646
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0045 0.0185 0.0351
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0027 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.024 0.024
Trypanosoma brucei farnesyl pyrophosphate synthase 0.0112 0.0568 0.1241
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0027 0.0032
Plasmodium falciparum geranylgeranyl pyrophosphate synthase, putative 0.0112 0.0568 1
Brugia malayi hypothetical protein 0.0482 0.2671 0.5064
Schistosoma mansoni RAR-like nuclear receptor 0.094 0.5274 0.612
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0027 0.0052
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0503 0.279 1
Trypanosoma cruzi Emopamil binding protein, putative 0.0151 0.0787 0.1724
Brugia malayi CHD4 protein 0.0016 0.002 0.0039
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.094 0.5274 0.5274
Echinococcus multilocularis nuclear receptor nhr 48 0.0443 0.245 0.245
Schistosoma mansoni lamin 0.0059 0.0264 0.0307
Brugia malayi nuclear hormone receptor family member odr-7 0.0443 0.245 0.4646
Schistosoma mansoni neuropeptide receptor 0.0055 0.024 0.0279
Schistosoma mansoni hypothetical protein 0.0055 0.024 0.0279
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0019 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0034 0.0123 0.0234
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.004 0.0068
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Echinococcus granulosus g protein coupled receptor 0.0055 0.024 0.0283
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0098 0.0486 0.0572
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0087 0.0172
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0152 0.0289
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni cellular tumor antigen P53 0.0108 0.0544 0.0631
Schistosoma mansoni polycystin 1-related 0.0043 0.0174 0.0201
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0152 0.0177
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.024 0.0279
Plasmodium vivax geranylgeranyl pyrophosphate synthase 0.0112 0.0568 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0041 0.0164 0.0164
Echinococcus multilocularis Ankyrin 0.0016 0.002 0.002
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0185 0.0215
Onchocerca volvulus 0.0055 0.024 0.0456
Mycobacterium ulcerans polyprenyl synthetase IdsB 0.0028 0.0091 0.0322
Brugia malayi Nuclear hormone receptor family member nhr-14 0.094 0.5274 1
Giardia lamblia DINP protein human, muc B family 0.0021 0.0049 0.0724
Brugia malayi hypothetical protein 0.0043 0.0174 0.0329
Onchocerca volvulus 0.0045 0.0185 0.0351
Brugia malayi nuclear receptor NHR-88 0.0443 0.245 0.4646
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0055 0.024 0.0456
Brugia malayi Nuclear hormone receptor family member nhr-25 0.094 0.5274 1
Leishmania major DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Echinococcus granulosus tyrosine protein kinase Lyn 0.0041 0.0164 0.0193
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.024 0.0283
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0152 0.0358
Schistosoma mansoni amine GPCR 0.0055 0.024 0.0279
Leishmania major ferredoxin, 2fe-2s-like protein 0.0024 0.0068 0.0131
Loa Loa (eye worm) carboxylesterase 0.0074 0.0352 0.0667
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.094 0.5274 1
Echinococcus granulosus g protein coupled receptor 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi G-protein coupled receptor 0.0055 0.024 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Echinococcus granulosus sex peptide receptor 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis serotonin receptor 0.0055 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0185 0.0215
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0152 0.0771
Plasmodium falciparum amino acid transporter, putative 0.0045 0.0185 0.3258
Onchocerca volvulus 0.0055 0.024 0.0456
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0009 0.0011
Trypanosoma brucei cytochrome P450, putative 0.0038 0.0148 0.0309
Schistosoma mansoni nuclear receptor 0.0443 0.245 0.2844
Echinococcus multilocularis neuropeptide receptor 0.0055 0.024 0.024
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0152 0.0771
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0038 0.0148 0.0529
Onchocerca volvulus 0.0045 0.0185 0.0351
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0063 0.0286 0.0543
Brugia malayi Doublecortin family protein 0.0043 0.0174 0.0329
Schistosoma mansoni cpg binding protein 0.0066 0.0307 0.0356
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0185 0.0215
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.0351
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0021 0.0049 0.0057
Brugia malayi ecdysteroid receptor 0.094 0.5274 1
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0047 0.0088
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.024 0.0456
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0049 0.0172
Schistosoma mansoni hypothetical protein 0.0043 0.0174 0.0201
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0133 0.0684 0.1496
Onchocerca volvulus 0.0055 0.024 0.0456
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0013 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Giardia lamblia [2Fe-2S] ferredoxin 0.0024 0.0068 0.107
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0009 0.0158
Onchocerca volvulus 0.0055 0.024 0.0456
Brugia malayi Cytochrome P450 family protein 0.0019 0.004 0.0075
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0179 0.0208
Schistosoma mansoni farnesyl pyrophosphate synthase 0.0112 0.0568 0.066
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.024 0.0279
Leishmania major solanesyl-diphosphate synthase, putative 0.0028 0.0091 0.0181
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0019 0.004 0.0139
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.024 0.0456
Schistosoma mansoni steroid hormone receptor ad4bp 0.094 0.5274 0.612
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0027 0.0032
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.024 0.0283
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0178 0.021
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0152 0.0177
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0133 0.0684 0.0684
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0044 0.0178 0.0178
Giardia lamblia GTOR 0.0049 0.021 0.359
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Brugia malayi Ubiquitin conjugating enzyme protein 13 0.0042 0.0166 0.0314
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0684 0.2448
Echinococcus granulosus serotonin receptor 0.0055 0.024 0.0283
Echinococcus granulosus carboxylesterase 5A 0.0074 0.0352 0.0414
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0564 0.3137 0.5948
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0027 0.0398
Schistosoma mansoni thyroid hormone receptor 0.094 0.5274 0.612
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0019 0.004 0.0197
Echinococcus granulosus lamin 0.0059 0.0264 0.0311
Echinococcus multilocularis cpg binding protein 0.0066 0.0307 0.0307
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Echinococcus granulosus neuropeptide receptor A26 0.0555 0.3088 0.3633
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0068 0.0131
Leishmania major DNA polymerase eta, putative 0.0021 0.0049 0.0088
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0055 0.024 0.024
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0152 0.0179
Loa Loa (eye worm) phospholipase D 0.0021 0.005 0.0095
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.094 0.5274 0.612
Loa Loa (eye worm) hypothetical protein 0.0379 0.2083 0.395
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0238 0.0451
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0027 0.0052
Loa Loa (eye worm) hypothetical protein 0.0379 0.2083 0.395
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0032 0.0109 0.0206
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Treponema pallidum quinoline 2-oxidoreductase 0.0121 0.0615 0.3898
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0019 0.004 0.0197
Brugia malayi protein-tyrosine kinase 0.0037 0.0141 0.0268
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0032
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0047 0.0055
Onchocerca volvulus 0.0482 0.2671 0.5064
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0087 0.1521
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.094 0.5274 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0038 0.0073
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0148 0.0281
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.024 0.0283
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Brugia malayi M-phase phosphoprotein, mpp8 0.011 0.0556 0.1055
Onchocerca volvulus 0.0013 0.0001 0.0001
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0329
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0045 0.0185 0.0185
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0017 0.0023 0.0044
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0178 0.021
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.024 0.024
Trypanosoma cruzi farnesyl pyrophosphate synthase, putative 0.0112 0.0568 0.1241
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Leishmania major phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.0032
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0081 0.019
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0289
Echinococcus multilocularis acetylcholinesterase 0.0074 0.0352 0.0352
Trichomonas vaginalis glucosylceramidase, putative 0.0564 0.3137 0.7385
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0178 0.0376
Mycobacterium ulcerans electron transfer protein 0.0024 0.0068 0.0242
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0098 0.0486 0.0486
Brugia malayi nuclear hormone receptor family member nhr-6 0.0443 0.245 0.4646
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0027 0.004
Onchocerca volvulus 0.0055 0.024 0.0456
Schistosoma mansoni neuroligin 3 (S09 family) 0.0013 0.0001 0.0001
Onchocerca volvulus 0.0046 0.0194 0.0367
Leishmania major cytochrome p450-like protein 0.0038 0.0148 0.0309
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0083 0.0404 1
Schistosoma mansoni cpg binding protein 0.0063 0.0286 0.0332
Echinococcus multilocularis geminin 0.0184 0.0978 0.0978
Onchocerca volvulus 0.0059 0.0264 0.0501
Entamoeba histolytica hypothetical protein 0.0039 0.0152 0.2667
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.024 0.024
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.024 0.024
Toxoplasma gondii endonuclease IV APN 0.0083 0.0404 0.5908
Echinococcus multilocularis sex peptide receptor 0.0055 0.024 0.024
Echinococcus granulosus Nuclear hormone receptor HR96 0.0443 0.245 0.2883
Trichomonas vaginalis Ferredoxin 2 0.0024 0.0068 0.0161
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0044 0.0178 0.0207
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0045 0.0185 0.0185
Entamoeba histolytica hypothetical protein 0.0039 0.0152 0.2667
Loa Loa (eye worm) hypothetical protein 0.0021 0.005 0.0095
Loa Loa (eye worm) hypothetical protein 0.0496 0.2753 0.522
Trypanosoma cruzi target of rapamycin kinase 3 0.0039 0.0152 0.0318
Brugia malayi hypothetical protein 0.0496 0.2753 0.522
Plasmodium vivax SET domain protein, putative 0.0034 0.0123 0.2168
Schistosoma mansoni netrin receptor unc5 0.0016 0.0019 0.0022
Echinococcus granulosus nuclear receptor 2DBD gamma 0.094 0.5274 0.6204
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0022 0.0054 0.0103
Brugia malayi Protein K4 0.0018 0.0032 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.019
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0014 0.0009 0.0132
Onchocerca volvulus Putative phospholipase D 0.0021 0.005 0.0095
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0027 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0043 0.0102
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0042 0.0166 0.0347
Echinococcus granulosus ferredoxin 0.0024 0.0068 0.008
Trypanosoma brucei phosphatidylglycerolphosphate synthase, mitochondrial 0.0018 0.0032 0.0051
Mycobacterium ulcerans hypothetical protein 0.0039 0.0152 0.0543
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0019 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0185 0.0218
Brugia malayi tailless protein 0.0443 0.245 0.4646
Loa Loa (eye worm) hypothetical protein 0.0265 0.1436 0.2723
Echinococcus granulosus nuclear receptor nhr 48 0.0443 0.245 0.2883
Echinococcus granulosus phospholipase D1 0.0113 0.057 0.0671
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0125 0.0642 0.3263
Brugia malayi Nuclear hormone receptor-like 1 0.094 0.5274 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0058 0.0258 0.049
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0152 0.0771
Echinococcus granulosus multidrug resistance associated protein 7 0.0014 0.0009 0.0011
Schistosoma mansoni thyroid hormone receptor 0.094 0.5274 0.612
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0021 0.0049 0.0093
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.2709
Echinococcus granulosus nuclear factor of activated T cells 5 0.0081 0.0388 0.0457
Brugia malayi Nuclear hormone receptor family member nhr-3 0.094 0.5274 1
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.0351
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0049 0.0093
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.024 0.0279
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0112 0.0568 0.2035
Plasmodium falciparum transporter, putative 0.0045 0.0185 0.3258
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.0091 0.0181
Toxoplasma gondii histone lysine methyltransferase SET1 0.012 0.0612 0.8954
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0049 0.0088
Brugia malayi cytochrome P450 0.0019 0.004 0.0075
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0134 0.0693 0.0804
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0188 0.1001 0.1001
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0049 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0564 0.3137 0.7385
Loa Loa (eye worm) hypothetical protein 0.0027 0.0085 0.0161
Plasmodium falciparum adrenodoxin-type ferredoxin, putative 0.0024 0.0068 0.1201
Schistosoma mansoni lozenge 0.006 0.0273 0.0317
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0041 0.0164 0.0164
Brugia malayi hypothetical protein 0.0443 0.245 0.4646
Toxoplasma gondii ubiquitin-conjugating enzyme subfamily protein 0.0042 0.0166 0.2422
Onchocerca volvulus 0.0013 0.0001 0.0001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.024 0.0456
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0041 0.0164 0.0193
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0017
Echinococcus granulosus tm gpcr rhodopsin 0.0622 0.3465 0.4076
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0341 0.0736
Echinococcus granulosus Nuclear hormone receptor HR96 0.0443 0.245 0.2883
Echinococcus granulosus acetylcholinesterase 0.0074 0.0352 0.0414
Onchocerca volvulus 0.0063 0.0286 0.0543
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.024 0.024
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0684 0.0793
Loa Loa (eye worm) hypothetical protein 0.0054 0.0238 0.0451
Mycobacterium tuberculosis Conserved protein 0.0039 0.0152 0.0771
Mycobacterium ulcerans endonuclease IV 0.0083 0.0404 0.1445
Brugia malayi Death domain containing protein 0.0016 0.0019 0.0036
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.024 0.0456
Echinococcus multilocularis musashi 0.0059 0.0264 0.0264
Echinococcus granulosus tyrosine protein kinase Src64B 0.0041 0.0164 0.0193
Entamoeba histolytica geranylgeranyl pyrophosphate synthase, putative 0.0028 0.0091 0.159
Giardia lamblia MRP-like ABC transporter 0.0014 0.0009 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.094 0.5274 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Trypanosoma cruzi cardiolipin synthetase, putative 0.0039 0.0153 0.0319
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.024 0.0283
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0123 0.0143
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0148 0.0309
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0185 0.0218
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.024 0.0279
Entamoeba histolytica ABC transporter, putative 0.0014 0.0009 0.0158
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.004 0.0158 0.0299
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.094 0.5274 0.5274
Echinococcus granulosus retinoic acid receptor rxr beta a 0.1047 0.5884 0.6922
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Schistosoma mansoni multidrug resistance protein 0.0014 0.0009 0.0011
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.094 0.5274 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0178 0.042
Brugia malayi photoreceptor-specific nuclear receptor 0.094 0.5274 1
Loa Loa (eye worm) carboxylesterase 0.0013 0.0001 0.0001
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0379 0.2083 0.395
Loa Loa (eye worm) nuclear receptor NHR-67 0.0443 0.245 0.4646
Loa Loa (eye worm) hypothetical protein 0.0044 0.0178 0.0338
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.094 0.5274 1
Mycobacterium leprae Probable lipase LipE 0.0039 0.0152 0.3095
Brugia malayi Nuclear hormone receptor family member nhr-25 0.094 0.5274 1
Mycobacterium tuberculosis Conserved protein 0.0039 0.0152 0.0771
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0097 0.0228
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0019 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.024 0.0279
Trichomonas vaginalis glucosylceramidase, putative 0.0564 0.3137 0.7385
Loa Loa (eye worm) TK protein kinase 0.0033 0.0118 0.0223
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0289
Loa Loa (eye worm) hypothetical protein 0.0482 0.2671 0.5064
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.0351
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.094 0.5274 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.024 0.024
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0256 0.1387 0.4971
Brugia malayi Melatonin receptor type 1A 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0027 0.0027
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.024 0.0283
Echinococcus granulosus orexin receptor type 2 0.0055 0.024 0.0283
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0443 0.245 0.4646
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0443 0.245 0.245
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0112 0.0568 0.1338
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0023 0.0062 0.0117
Loa Loa (eye worm) CHromoDomain protein family member 0.0016 0.002 0.0039
Brugia malayi hypothetical protein 0.0028 0.0087 0.0164
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0019 0.004 0.0139
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Trichomonas vaginalis Ferredoxin 1 0.0024 0.0068 0.0161
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.094 0.5274 0.612
Schistosoma mansoni hypothetical protein 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.0351
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0443 0.245 0.245
Echinococcus granulosus neuropeptide receptor 0.0055 0.024 0.0283
Echinococcus granulosus fmrfamide receptor 0.0055 0.024 0.0283
Brugia malayi Nuclear hormone receptor family member nhr-49 0.094 0.5274 1
Schistosoma mansoni cytochrome P450 0.0019 0.004 0.0046
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis FTZ F1 alpha 0.094 0.5274 0.5274
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0027 0.0027
Brugia malayi conserved hypotetical protein 0.0443 0.245 0.4646
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0194 0.0225
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.024 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.019
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0024 0.0068 0.0343
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0152 0.0358
Loa Loa (eye worm) hypothetical protein 0.0073 0.0347 0.0658
Brugia malayi Polyprenyl synthetase family protein 0.0028 0.0091 0.0172
Loa Loa (eye worm) CYP4Cod1 0.0038 0.0148 0.0281
Schistosoma mansoni lipoxygenase 0.0111 0.0562 0.0652
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0049 0.021 0.0445
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0496 0.2753 0.522
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0551 0.3061 0.3061
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.024 0.0456
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.024 0.024
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0083 0.0404 0.7105
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0145 0.0754 0.27
Brugia malayi ubiquitin conjugating enzyme protein 13 0.0042 0.0166 0.0314
Toxoplasma gondii ferodoxin FD 0.0024 0.0068 0.0998
Plasmodium vivax octaprenyl pyrophosphate synthase, putative 0.0028 0.0091 0.1595
Onchocerca volvulus 0.0151 0.0787 0.1491
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.024 0.0456
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1528 0.8617 1
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0358 0.1965 0.7044
Brugia malayi larval opioid receptor 0.0055 0.024 0.0456
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0443 0.245 0.4646
Echinococcus multilocularis farnesyl pyrophosphate synthase 0.0112 0.0568 0.0568
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0044 0.0178 0.0207
Entamoeba histolytica phospholipase D active site domain-containing protein 0.0095 0.0468 0.8201
Echinococcus granulosus ubiquitin specific protease 41 0.0044 0.0178 0.021
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.094 0.5274 1
Brugia malayi hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0025 0.0029
Giardia lamblia Farnesyl diphosphate synthase 0.0112 0.0568 1
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0265 0.1436 0.1666
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0019 0.004 0.0197
Brugia malayi Phospholipase d protein 1 0.0113 0.057 0.1081
Echinococcus multilocularis GPCR, family 2 0.0017 0.0027 0.0027
Onchocerca volvulus 0.0055 0.024 0.0456
Mycobacterium ulcerans electron transfer protein FdxB 0.0024 0.0068 0.0242
Onchocerca volvulus 0.0055 0.024 0.0456
Echinococcus multilocularis prenyl (decaprenyl) diphosphate synthase 0.0028 0.0091 0.0091
Echinococcus multilocularis phospholipase D1 0.0113 0.057 0.057
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0019 0.004 0.0139
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.024 0.0279
Brugia malayi nuclear hormone receptor 0.094 0.5274 1
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0054 0.0272
Onchocerca volvulus 0.0055 0.024 0.0456
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0049 0.021 0.0445
Brugia malayi nuclear hormone receptor 0.0443 0.245 0.4646
Echinococcus granulosus intermediate filament protein 0.0059 0.0264 0.0311
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0022 0.0054 0.0191
Trypanosoma cruzi PAB1-binding protein , putative 0.0028 0.0087 0.0172
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0496 0.2753 0.3239
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0019 0.004 0.0197
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0019 0.004 0.0197
Schistosoma mansoni adenoreceptor 0.0055 0.024 0.0279
Entamoeba histolytica geranylgeranyl pyrophosphate synthetase, putative 0.0028 0.0091 0.159
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0019 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Loa Loa (eye worm) hypothetical protein 0.0073 0.0347 0.0658
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0045 0.0185 0.4118
Onchocerca volvulus 0.0443 0.245 0.4646
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0039 0.0152 0.0318
Echinococcus multilocularis serotonin receptor 0.0055 0.024 0.024
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.024 0.0456
Loa Loa (eye worm) norepinephrine transporter 0.0265 0.1436 0.2723
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0027 0.0027
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0013 0.0005 0.0011
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0143 0.0336
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0289
Onchocerca volvulus 0.0055 0.024 0.0456
Loa Loa (eye worm) solute carrier family 6 member 4 0.0265 0.1436 0.2723
Schistosoma mansoni tyrosine kinase 0.0041 0.0164 0.019
Leishmania major hypothetical protein, conserved 0.0151 0.0787 0.1724
Onchocerca volvulus 0.0055 0.024 0.0456
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0098 0.0486 0.0564
Trichomonas vaginalis aldehyde oxidase, putative 0.0759 0.4248 1
Brugia malayi AKH receptor 0.0055 0.024 0.0456
Onchocerca volvulus 0.0013 0.0001 0.0001
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0125 0.0642 0.0642
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0152 0.0771
Echinococcus granulosus nuclear receptor 2DBD gamma 0.094 0.5274 0.6204
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.094 0.5274 0.5274
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0152 0.0358
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0125 0.0642 0.0745
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0807 0.4518 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0174 0.0174
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0021 0.0049 0.0049
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0123 0.0143
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.024 0.0456
Echinococcus multilocularis g protein coupled receptor 0.0055 0.024 0.024
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0125 0.0642 0.1217
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.004 0.0068
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.002 0.0046 0.0081
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0189
Chlamydia trachomatis endonuclease IV 0.0083 0.0404 1
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0024 0.0068 0.0242
Brugia malayi Carboxylesterase family protein 0.0074 0.0352 0.0667
Loa Loa (eye worm) runx1 0.006 0.0273 0.0518
Onchocerca volvulus 0.0055 0.024 0.0456
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0083 0.0404 0.2052
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.024 0.0283
Brugia malayi Polyprenyl synthetase family protein 0.0112 0.0568 0.1078
Onchocerca volvulus 0.0059 0.0264 0.0501
Plasmodium vivax amine transporter, putative 0.0045 0.0185 0.3258
Brugia malayi hypothetical protein 0.0018 0.0032 0.0061
Onchocerca volvulus Bile acid receptor homolog 0.094 0.5274 1
Plasmodium vivax phosphatidylglycerophosphate synthase, putative 0.0018 0.0032 0.0564
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0049 0.0245
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0017 0.0027 0.0135
Schistosoma mansoni zinc finger protein 0.0443 0.245 0.2844
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0019 0.004 0.0197
Loa Loa (eye worm) geranylgeranyl pyrophosphate synthetase 0.0028 0.0091 0.0172
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0038 0.0143 0.0336
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.024 0.0456
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni aldehyde dehydrogenase 0.0133 0.0684 0.0793
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0049 0.021 0.3672
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0238 0.0451
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0019 0.0023
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0152 0.0358
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.0341 0.5974
Treponema pallidum hypothetical protein 0.0102 0.0508 0.3099
Echinococcus granulosus Polycystic kidney disease protein 0.0043 0.0174 0.0204
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0151 0.0787 0.1724
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0152 0.0318
Mycobacterium ulcerans beta-lactamase 0.0039 0.0152 0.0543
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0043 0.0102
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0049 0.0088
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0125 0.0642 0.2299
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0185 0.0185
Schistosoma mansoni neuropeptide receptor 0.0055 0.024 0.0279
Brugia malayi ABC transporter transmembrane region family protein 0.0014 0.0009 0.0017
Schistosoma mansoni nuclear receptor nhr-48 0.0443 0.245 0.2844
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0095 0.0224
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0044 0.0178 0.0178
Loa Loa (eye worm) phosphatidylinositol 3 0.0017 0.0023 0.0044
Mycobacterium ulcerans lipase LipD 0.0039 0.0152 0.0543
Schistosoma mansoni myosin xvIII 0.0055 0.024 0.0279
Brugia malayi Nuclear hormone receptor family member nhr-19 0.094 0.5274 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0265 0.1436 0.2723
Echinococcus granulosus thyroid hormone receptor alpha 0.0443 0.245 0.2883
Onchocerca volvulus 0.0024 0.0068 0.0129
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Brugia malayi beta-lactamase family protein 0.0039 0.0152 0.0289
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.0351
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Echinococcus granulosus neuropeptide s receptor 0.0555 0.3088 0.3633
Loa Loa (eye worm) hypothetical protein 0.0022 0.0054 0.0103
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0049 0.021 0.0445
Brugia malayi multidrug resistance related protein 1 0.0014 0.0009 0.0017
Plasmodium falciparum LCCL domain-containing protein 0.0043 0.0174 0.3052
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Trypanosoma brucei NADH-ubiquinone oxidoreductase complex I subunit, putative 0.0024 0.0068 0.0131
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.024 0.0456
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.094 0.5274 0.6204
Leishmania major polyprenyl synthase, putative 0.0028 0.0091 0.0181
Loa Loa (eye worm) hypothetical protein 0.011 0.0556 0.1055
Echinococcus multilocularis carboxylesterase 5A 0.0074 0.0352 0.0352
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.094 0.5274 0.5274
Mycobacterium ulcerans hypothetical protein 0.0022 0.0054 0.0191
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Treponema pallidum sodium- and chloride- dependent transporter 0.0265 0.1436 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.024 0.024
Entamoeba histolytica hypothetical protein 0.0039 0.0152 0.2667
Toxoplasma gondii hypothetical protein 0.0045 0.0185 0.2709
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.024 0.0456
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.0091 0.0181
Loa Loa (eye worm) doublecortin family protein 0.0043 0.0174 0.0329
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0017 0.0023 0.0032
Echinococcus granulosus g protein coupled receptor 0.0055 0.024 0.0283
Echinococcus granulosus tyrosine protein kinase Src42A 0.0041 0.0164 0.0193
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Schistosoma mansoni lipoxygenase 0.0188 0.1001 0.1162
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.094 0.5274 0.612
Echinococcus granulosus somatostatin receptor 0.0055 0.024 0.0283
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0019 0.004 0.0139
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0028 0.0091 0.0107
Loa Loa (eye worm) hypothetical protein 0.0074 0.0352 0.0667
Trichomonas vaginalis ubiquitin-conjugating enzyme E2, putative 0.0042 0.0166 0.039
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0016 0.0019 0.0036
Loa Loa (eye worm) hypothetical protein 0.0496 0.2753 0.522
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0152 0.0771
Schistosoma mansoni microtubule-associated protein tau 0.1507 0.85 0.9864
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.024 0.0279
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0044 0.0178 0.3127
Schistosoma mansoni hypothetical protein 0.0019 0.004 0.0046
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.024 0.024
Brugia malayi ImpB/MucB/SamB family protein 0.0021 0.0049 0.0093
Entamoeba histolytica hypothetical protein 0.0014 0.0009 0.0158
Echinococcus granulosus dnaJ subfamily B 0.0893 0.5009 0.5893
Trypanosoma cruzi solanesyl-diphosphate synthase, putative 0.0028 0.0091 0.0181
Brugia malayi Intermediate filament tail domain containing protein 0.0059 0.0264 0.0501
Brugia malayi hypothetical protein 0.0018 0.0031 0.0058
Echinococcus multilocularis fmrfamide receptor 0.0055 0.024 0.024
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0152 0.0177
Echinococcus granulosus phospholipase D 0.01 0.0496 0.0583
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0188 0.1001 0.1178
Trypanosoma brucei DNA polymerase IV, putative 0.0021 0.0049 0.0088
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0044 0.0178 0.042
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.0341 0.0341
Echinococcus multilocularis multidrug resistance associated protein 1 0.0014 0.0009 0.0009
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0189
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Trypanosoma cruzi ubiquitin-conjugating enzyme E2, putative 0.0042 0.0166 0.0347
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Brugia malayi G protein-coupled receptor 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.011 0.0557 0.1056
Brugia malayi SET domain containing protein 0.0015 0.0015 0.0028
Echinococcus multilocularis thyroid hormone receptor alpha 0.094 0.5274 0.5274
Loa Loa (eye worm) polyprenyl synthetase 0.0028 0.0091 0.0172
Onchocerca volvulus Glucosylceramidase homolog 0.037 0.2034 0.3857
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0152 0.0771
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0019 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0496 0.2753 0.522
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0045 0.0185 0.0218
Mycobacterium ulcerans polyprenyl diphosphate synthetase, GrcC1 0.0028 0.0091 0.0322
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi Nuclear hormone receptor family member nhr-41 0.094 0.5274 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.024 0.0456
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0042 0.0166 0.0314
Echinococcus granulosus tyrosine protein kinase Src42A 0.0036 0.0135 0.0158
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0041 0.0164 0.0164
Echinococcus granulosus ubiquitin conjugating enzyme E2 N 0.0042 0.0166 0.0195
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0152 0.2679
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0379 0.2083 0.2417
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0112 0.0568 0.8315
Toxoplasma gondii hypothetical protein 0.0045 0.0185 0.2709
Mycobacterium ulcerans geranylgeranyl pyrophosphate synthase 0.0112 0.0568 0.2035
Schistosoma mansoni terminal deoxycytidyl transferase 0.0021 0.0049 0.0057
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0358 0.1965 0.7044
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0049 0.021 0.0247
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0009 0.0158
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Schistosoma mansoni neuropeptide receptor 0.0055 0.024 0.0279
Trypanosoma cruzi farnesyl pyrophosphate synthase 0.0112 0.0568 0.1241
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0759 0.4248 1
Schistosoma mansoni rab6-interacting 0.0043 0.0174 0.0201
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0117 0.0276
Onchocerca volvulus 0.0261 0.1414 0.2681
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0141 0.0166
Onchocerca volvulus 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0265 0.1436 0.2723
Brugia malayi Serotonin receptor 0.0559 0.3106 0.5891
Echinococcus multilocularis fmrfamide receptor 0.0055 0.024 0.024
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Giardia lamblia Multidrug resistance-associated protein 1 0.0014 0.0009 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0482 0.2671 0.5064
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0019 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni hypothetical protein 0.0893 0.5009 0.5813
Trichomonas vaginalis geranylgeranyl pyrophosphate synthase, putative 0.0112 0.0568 0.1338
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.024 0.0279
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0152 0.0289
Brugia malayi orphan nuclear receptor NR2E1 0.0443 0.245 0.4646
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0358 0.1965 1
Loa Loa (eye worm) hypothetical protein 0.0095 0.0468 0.0887
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.004 0.0068
Onchocerca volvulus 0.0039 0.0152 0.0289
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0027 0.0032
Brugia malayi Steroid receptor seven-up type 2 0.094 0.5274 1
Onchocerca volvulus 0.0055 0.024 0.0456
Entamoeba histolytica deoxycytidyl transferase, putative 0.0021 0.0049 0.0857
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0123 0.0123
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0164 0.0164
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0141 0.0141
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Schistosoma mansoni nuclear hormone receptor 0.0443 0.245 0.2844
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0024 0.0068 0.0242
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0019 0.004 0.0139
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Echinococcus granulosus farnesyl pyrophosphate synthase 0.0112 0.0568 0.0669
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0017 0.0025 0.0025
Schistosoma mansoni hypothetical protein 0.0016 0.0019 0.0022
Brugia malayi Nuclear hormone receptor-like 1 0.0496 0.2753 0.522
Echinococcus multilocularis tumor protein p63 0.0738 0.4126 0.4126
Plasmodium vivax ubiquitin-conjugating enzyme E2 N, putative 0.0042 0.0166 0.2912
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0766
Echinococcus granulosus multidrug resistance associated protein 1 0.0014 0.0009 0.0011
Onchocerca volvulus 0.011 0.0556 0.1055
Loa Loa (eye worm) hypothetical protein 0.0496 0.2753 0.522
Onchocerca volvulus Adrenodoxin, mitochondrial homolog 0.0024 0.0068 0.0129
Echinococcus multilocularis dnaJ subfamily B 0.0893 0.5009 0.5009
Loa Loa (eye worm) acetylcholinesterase 1 0.0074 0.0352 0.0667
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.0341 0.0646
Schistosoma mansoni Tr4/Tr2 (homologue) 0.094 0.5274 0.612
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0044 0.0178 0.3035
Brugia malayi F/Y-rich N-terminus family protein 0.002 0.0045 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0027 0.004
Mycobacterium tuberculosis Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate 0.0028 0.0091 0.0457
Schistosoma mansoni glutathione synthetase 0.0028 0.0091 0.0105
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0443 0.245 0.245
Trichomonas vaginalis glucosylceramidase, putative 0.039 0.2147 0.5055
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Schistosoma mansoni ubiquitin conjugating enzyme 13 0.0042 0.0166 0.0192
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0068 0.0131
Schistosoma mansoni amine GPCR 0.0418 0.2304 0.2674
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0006
Leishmania major ferredoxin 2fe-2s-like protein 0.0024 0.0068 0.0131
Echinococcus multilocularis BC026374 protein (S09 family) 0.0013 0.0001 0.0001
Mycobacterium tuberculosis Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) 0.0112 0.0568 0.2889
Trypanosoma brucei ubiquitin-protein ligase, putative 0.0042 0.0166 0.0347
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.019
Schistosoma mansoni sodium-dependent amino acid transporter 0.0045 0.0185 0.0215
Echinococcus multilocularis 0.0019 0.004 0.004
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni neuropeptide receptor 0.0055 0.024 0.0279
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0164 0.0164
Mycobacterium tuberculosis Conserved hypothetical protein 0.0021 0.0049 0.0245
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0017 0.0023 0.0023
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0021 0.0049 0.0058
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Echinococcus granulosus para nitrobenzyl esterase 0.0013 0.0001 0.0001
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0684 0.2448
Chlamydia trachomatis geranylgeranyl pyrophosphate synthase 0.0028 0.0091 0.1577
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0027 0.0027
Schistosoma mansoni multidrug resistance protein 0.0014 0.0009 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Loa Loa (eye worm) cytochrome P450 family protein 0.0038 0.0148 0.0281
Brugia malayi hypothetical protein 0.0043 0.0174 0.0329
Loa Loa (eye worm) serotonin transporter b 0.0265 0.1436 0.2723
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.024 0.0279
Echinococcus granulosus g-protein coupled receptor 0.0055 0.024 0.0283
Echinococcus granulosus dna polymerase kappa 0.0021 0.0049 0.0058
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.024 0.024
Brugia malayi GnHR receptor homolog 0.0055 0.024 0.0456
Trypanosoma brucei unspecified product 0.0014 0.0012 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Toxoplasma gondii ferredoxin, putative 0.0024 0.0068 0.0998
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.024 0.0283
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0027 0.0081 0.019
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Onchocerca volvulus 0.0055 0.024 0.0456
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0168 0.0197
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0133 0.0684 0.0804
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus granulosus lamin dm0 0.0059 0.0264 0.0311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0152 0.0358
Echinococcus multilocularis neuropeptide receptor A26 0.0555 0.3088 0.3088
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0019 0.004 0.0139
Schistosoma mansoni opsin-like receptor 0.0055 0.024 0.0279
Brugia malayi nuclear receptor NHR-67 0.0443 0.245 0.4646
Plasmodium falciparum ataxin-2 like protein, putative 0.0028 0.0087 0.1521
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0152 0.0152
Toxoplasma gondii polyprenyl synthetase superfamily protein 0.0028 0.0091 0.1326
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0027 0.004
Loa Loa (eye worm) steroid hormone receptor 0.094 0.5274 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.024 0.0456
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0019 0.004 0.0197
Mycobacterium tuberculosis Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) 0.0028 0.0091 0.0457
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0006
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0123 0.1802
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0443 0.245 0.4646
Onchocerca volvulus 0.0043 0.0174 0.0329
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.024 0.024
Mycobacterium ulcerans oxidoreductase 0.0024 0.0068 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0014 0.0012 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0059 0.0264 0.0501
Brugia malayi beta-lactamase 0.0039 0.0152 0.0289
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0151 0.0787 0.1724
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.0341 0.0736
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.024 0.024
Wolbachia endosymbiont of Brugia malayi ferredoxin 0.0024 0.0068 0.6178
Entamoeba histolytica phospholipase D, putative 0.0113 0.057 1
Brugia malayi geranylgeranyl pyrophosphate synthetase 0.0028 0.0091 0.0172
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.024 0.0456
Loa Loa (eye worm) nuclear hormone receptor 0.0443 0.245 0.4646
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0141 0.0166
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0055 0.024 0.0456
Brugia malayi isocitrate dehydrogenase 0.0017 0.0027 0.0052
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.024 0.0283
Echinococcus multilocularis sodium and chloride dependent glycine 0.0045 0.0185 0.0185
Schistosoma mansoni acetylcholinesterase 0.0013 0.0001 0.0001
Echinococcus multilocularis microtubule associated protein 2 0.1507 0.85 0.85
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis lamin dm0 0.0059 0.0264 0.0264
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0044 0.0178 0.0376
Echinococcus multilocularis dna polymerase kappa 0.0021 0.0049 0.0049
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0028 0.0091 0.0091
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0027 0.0051
Schistosoma mansoni adrenodoxin 0.0024 0.0068 0.0079
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.004 0.0047
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0032
Schistosoma mansoni hypothetical protein 0.0037 0.014 0.0163
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus multilocularis geranylgeranyl pyrophosphate synthase 0.0028 0.0091 0.0091
Plasmodium vivax hypothetical protein, conserved 0.0045 0.0185 0.3258
Trichomonas vaginalis Ferredoxin 4 0.0024 0.0068 0.0161
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0043 0.0174 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0185 0.0215
Schistosoma mansoni hypothetical protein 0.0057 0.0252 0.0292
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.2709
Schistosoma mansoni nuclear hormone receptor 0.0443 0.245 0.2844
Echinococcus granulosus neuropeptide receptor 0.0055 0.024 0.0283
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0443 0.245 0.245
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.024 0.0279
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0027 0.0479
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0152 0.0358
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0019 0.004 0.0197
Entamoeba histolytica protein kinase, putative 0.0033 0.0118 0.2063
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.004 0.0068
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.024 0.0283
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0045 0.0185 0.2709
Schistosoma mansoni coup transcription factor 0.094 0.5274 0.612
Brugia malayi hypothetical protein 0.0443 0.245 0.4646
Toxoplasma gondii aldehyde dehydrogenase 0.0133 0.0684 1
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0037 0.014 0.0266
Echinococcus multilocularis serotonin transporter 0.0265 0.1436 0.1436
Loa Loa (eye worm) hypothetical protein 0.0018 0.0032 0.0061
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0045 0.0185 0.0215
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0443 0.245 0.2844
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.021 0.0493
Echinococcus granulosus cpg binding protein 0.0066 0.0307 0.0361
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0152 0.0543
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Brugia malayi Nuclear hormone receptor family member nhr-19 0.094 0.5274 1
Schistosoma mansoni amine GPCR 0.0055 0.024 0.0279
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0013 0.0001 0.0002
Brugia malayi Phospholipase D. Active site motif family protein 0.0039 0.0153 0.029
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0041 0.0164 0.0164
Brugia malayi beta-lactamase family protein 0.0039 0.0152 0.0289
Trichomonas vaginalis Ferredoxin 7 0.0024 0.0068 0.0161
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0014 0.0009 0.0017
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.0341 0.0736
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0027 0.004
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.024 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Brugia malayi Protein kinase domain containing protein 0.0016 0.0019 0.0036
Onchocerca volvulus 0.0013 0.0001 0.0001
Echinococcus granulosus dna polymerase eta 0.0021 0.0049 0.0058
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.004 0.0158 0.0158
Treponema pallidum hypothetical protein 0.0123 0.0631 0.4019
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0044 0.0178 0.0338
Trypanosoma brucei unspecified product 0.0014 0.0012 0.0006
Loa Loa (eye worm) hypothetical protein 0.0108 0.0544 0.1031
Mycobacterium ulcerans epimerase 0.0022 0.0054 0.0191
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.024 0.0456
Trypanosoma brucei cardiolipin synthetase, putative 0.0039 0.0153 0.0319
Onchocerca volvulus 0.0265 0.1436 0.2723
Schistosoma mansoni retinoic acid receptor RXR 0.1047 0.5884 0.6828
Onchocerca volvulus 0.0055 0.024 0.0456
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.094 0.5274 0.6204
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0049 0.021 0.0243
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.094 0.5274 1
Brugia malayi Cytochrome P450 family protein 0.0061 0.0277 0.0526
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0019 0.004 0.0197
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi 2Fe-2S iron-sulfur cluster binding domain containing protein 0.0024 0.0068 0.0129
Leishmania major farnesyl pyrophosphate synthase 0.0112 0.0568 0.1241
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.024 0.024
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.024 0.024
Echinococcus granulosus sodium and chloride dependent glycine 0.0045 0.0185 0.0218
Mycobacterium tuberculosis Conserved protein 0.0039 0.0152 0.0771
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0152 0.0543
Trypanosoma brucei Emopamil binding protein, putative 0.0151 0.0787 0.1724
Loa Loa (eye worm) polyprenyl synthetase 0.0112 0.0568 0.1078
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0049 0.021 0.0445
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0019 0.0036
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0019 0.004 0.0197
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0024 0.0068 0.0974
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0097 0.0228
Trypanosoma cruzi adrenodoxin precursor, putative 0.0024 0.0068 0.0131
Brugia malayi ecdysone receptor 0.0443 0.245 0.4646
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0027 0.0081 0.019
Brugia malayi Uncoordinated protein 44 0.0016 0.0019 0.0036
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0021 0.0049 0.0115
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0152 0.0358
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.024 0.024
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0164 0.0193
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0027 0.0032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0019 0.0036
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0117 0.0594 0.1126
Schistosoma mansoni multidrug resistance protein 0.0014 0.0009 0.0011
Plasmodium vivax multidomain scavenger receptor, putative 0.0043 0.0174 0.3052
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0013 0.0001 0.0001
Echinococcus multilocularis Adrenodoxin, mitochondrial 0.0024 0.0068 0.0068
Schistosoma mansoni hypothetical protein 0.0184 0.0978 0.1135
Giardia lamblia ABC transporter, putative 0.0014 0.0009 0.0011
Schistosoma mansoni tyrosine kinase 0.0041 0.0164 0.019
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0168 0.0168
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0019 0.0036
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0032
Schistosoma mansoni hypothetical protein 0.0184 0.0978 0.1135
Echinococcus granulosus neuroligin 0.0013 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Trypanosoma cruzi cardiolipin synthetase, putative 0.0039 0.0153 0.0319
Echinococcus multilocularis somatostatin receptor 0.0055 0.024 0.024
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0019 0.004 0.0139
Echinococcus granulosus BC026374 protein S09 family 0.0013 0.0001 0.0001
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.094 0.5274 1
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0256 0.1387 0.4971
Schistosoma mansoni CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 0.0018 0.0032 0.0037
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0152 0.0358
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.0091 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0009 0.0158
Loa Loa (eye worm) hypothetical protein 0.0021 0.0049 0.0093
Schistosoma mansoni histamine h1 receptor 0.0055 0.024 0.0279
Schistosoma mansoni intermediate filament proteins 0.0059 0.0264 0.0307
Onchocerca volvulus 0.0108 0.0544 0.1031
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0151 0.0787 0.1724
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0289
Leishmania major ubiquitin-conjugating enzyme e2, putative 0.0042 0.0166 0.0347
Trichomonas vaginalis DNA polymerase eta, putative 0.0021 0.0049 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.019
Wolbachia endosymbiont of Brugia malayi geranylgeranyl pyrophosphate synthase 0.0028 0.0091 1
Schistosoma mansoni hypothetical protein 0.0039 0.0152 0.0177
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Trypanosoma cruzi polyprenyl synthase, putative 0.0028 0.0091 0.0181
Trichomonas vaginalis glucosylceramidase, putative 0.039 0.2147 0.5055
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.024 0.0283
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0278 0.1509 0.1751
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.004 0.0158 0.0299
Trichomonas vaginalis esterase, putative 0.0039 0.0152 0.0358
Echinococcus granulosus acetylcholinesterase 0.0074 0.0352 0.0414
Plasmodium vivax cardiolipin synthetase, putative 0.0018 0.0032 0.0564
Echinococcus granulosus geminin 0.0184 0.0978 0.1151
Echinococcus multilocularis acetylcholinesterase 0.0074 0.0352 0.0352
Schistosoma mansoni BC026374 protein (S09 family) 0.0013 0.0001 0.0001
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Onchocerca volvulus 0.0043 0.0174 0.0329
Onchocerca volvulus 0.011 0.0556 0.1055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0185 0.0215
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0032
Echinococcus granulosus Ankyrin 0.0016 0.002 0.0023
Schistosoma mansoni gliotactin 0.0013 0.0001 0.0001
Leishmania major hypothetical protein, conserved 0.0024 0.0068 0.0131
Echinococcus multilocularis ferredoxin adrenodoxin 0.0024 0.0068 0.0068
Brugia malayi Serotonin receptor 0.0055 0.024 0.0456
Brugia malayi nuclear receptor RXR 0.0443 0.245 0.4646
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.0189
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Echinococcus multilocularis orexin receptor type 2 0.0055 0.024 0.024
Loa Loa (eye worm) carboxylesterase 0.0013 0.0001 0.0001
Echinococcus multilocularis neuropeptide s receptor 0.0555 0.3088 0.3088
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.094 0.5274 0.6204
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0068 0.0131
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0152 0.0358
Mycobacterium tuberculosis Possible oxygenase 0.0024 0.0068 0.0343
Entamoeba histolytica phospholipase D, putative 0.0113 0.057 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0289
Loa Loa (eye worm) TK protein kinase 0.0037 0.0141 0.0268
Brugia malayi Cytochrome P450 family protein 0.0038 0.0148 0.0281
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0017 0.0023 0.0028
Leishmania major cardiolipin synthetase, putative 0.0018 0.0032 0.0051
Onchocerca volvulus Protein ultraspiracle homolog 0.094 0.5274 1
Echinococcus granulosus FTZ F1 alpha 0.094 0.5274 0.6204
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0229 0.1234 0.234
Brugia malayi hypothetical protein 0.0039 0.0152 0.0288
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Toxoplasma gondii LsmAD domain-containing protein 0.0028 0.0087 0.1265
Trypanosoma cruzi DNA polymerase eta, putative 0.0021 0.0049 0.0088
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0098 0.0486 0.0564
Onchocerca volvulus 0.0443 0.245 0.4646
Schistosoma mansoni amine GPCR 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0095 0.0468 0.0887
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.024 0.0279
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.021 0.0493
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.024 0.0456
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0962 0.5399 0.5399
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0443 0.245 0.2883
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0019 0.004 0.0139
Onchocerca volvulus 0.0039 0.0152 0.0289
Loa Loa (eye worm) 2Fe-2S iron-sulfur cluster binding domain-containing protein 0.0024 0.0068 0.0129
Brugia malayi Cytochrome P450 family protein 0.0038 0.0148 0.0281
Mycobacterium leprae PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) 0.0028 0.0091 0.1404
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0019 0.0019
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.024 0.0279
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0068 0.0131
Brugia malayi Nuclear hormone receptor E75 0.0443 0.245 0.4646
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Trichomonas vaginalis glucosylceramidase, putative 0.0564 0.3137 0.7385
Trypanosoma brucei PAB1-binding protein , putative 0.0028 0.0087 0.0172
Schistosoma mansoni trans-prenyltransferase 0.0028 0.0091 0.0105
Brugia malayi cytoplasmic intermediate filament protein 0.0032 0.0109 0.0206
Trichomonas vaginalis Ferredoxin 6 0.0024 0.0068 0.0161
Leishmania major phosphatidylglycerophosphate synthase, putative 0.0021 0.005 0.0092
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Leishmania major adrenodoxin-like protein,ferredoxin, 2fe-2s-like protein 0.0024 0.0068 0.0131
Entamoeba histolytica ubiquitin-conjugating enzyme family protein 0.0042 0.0166 0.2903
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0019 0.004 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0041 0.0164 0.0193
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0045 0.0185 0.0218
Brugia malayi steroid hormone receptor 0.094 0.5274 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0016 0.002 0.0037
Schistosoma mansoni rab6-interacting 0.0043 0.0174 0.0201
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0068 0.0343
Schistosoma mansoni biogenic amine receptor 0.0055 0.024 0.0279
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0049 0.021 0.0397
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0178 0.0376
Trichomonas vaginalis PIKK family atypical protein kinase 0.0042 0.0169 0.0397
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0049 0.021 0.0445
Echinococcus multilocularis ubiquitin conjugating enzyme E2 N 0.0042 0.0166 0.0166
Plasmodium falciparum phosphatidylglycerophosphate synthase 0.0018 0.0032 0.0564
Schistosoma mansoni adrenodoxin 0.0024 0.0068 0.0079
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0019 0.0022
Toxoplasma gondii ABC1 family protein 0.0039 0.0152 0.2228
Trypanosoma brucei solanesyl-diphosphate synthase, putative 0.0028 0.0091 0.0181
Loa Loa (eye worm) hypothetical protein 0.0039 0.0152 0.0289
Schistosoma mansoni phospholipase D 0.0113 0.057 0.0662
Echinococcus granulosus hypothetical protein 0.0811 0.454 0.5341
Trypanosoma brucei C-8 sterol isomerase, putative 0.0807 0.4518 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0097 0.0228
Onchocerca volvulus 0.0039 0.0152 0.0289
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi Carboxylesterase family protein 0.0013 0.0001 0.0001
Echinococcus granulosus tachykinin peptides receptor 99D 0.0055 0.024 0.0283
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0164 0.0193
Plasmodium vivax ataxin-2 like protein, putative 0.0028 0.0087 0.1521
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0074 0.0352 0.0408
Echinococcus granulosus microtubule associated protein 2 0.1507 0.85 1
Echinococcus multilocularis neuropeptide receptor 0.0055 0.024 0.024
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.024 0.0456
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0622 0.3465 0.3465
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.019
Brugia malayi RE15519p 0.0055 0.024 0.0456
Chlamydia trachomatis ferredoxin 0.0024 0.0068 0.0974
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.004 0.0068
Loa Loa (eye worm) DR-78 0.0443 0.245 0.4646
Brugia malayi Nuclear hormone receptor-like 1 0.0496 0.2753 0.522
Loa Loa (eye worm) hypothetical protein 0.0043 0.0174 0.0329
Brugia malayi ORL1-like opioid receptor 0.0055 0.024 0.0456
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0125 0.0642 0.1404
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0141 0.0141
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.1353 0.6884
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0027 0.0027
Mycobacterium ulcerans hypothetical protein 0.0123 0.0631 0.2261
Schistosoma mansoni lamin 0.0059 0.0264 0.0307
Loa Loa (eye worm) cytochrome P450 0.0019 0.004 0.0075
Brugia malayi hypothetical protein 0.0496 0.2753 0.522
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.024 0.024
Trypanosoma brucei cardiolipin synthetase 0.0039 0.0153 0.0319
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0238 0.0451
Trypanosoma cruzi Emopamil binding protein, putative 0.0151 0.0787 0.1724
Brugia malayi SRC-1 0.0041 0.0164 0.0311
Entamoeba histolytica multidrug resistance protein, putative 0.0014 0.0009 0.0158
Echinococcus granulosus mixed lineage leukemia protein mll 0.0017 0.0025 0.0029
Schistosoma mansoni retinoid-x-receptor (RXR) 0.094 0.5274 0.612
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.024 0.0283
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.024 0.0279
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0152 0.0318
Brugia malayi Carboxylesterase family protein 0.0074 0.0352 0.0667
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0496 0.2753 0.3195
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0133 0.0684 0.3475
Echinococcus multilocularis Polycystic kidney disease protein 0.0043 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0412 0.2275 0.4313
Trichomonas vaginalis geranylgeranyl diphosphate synthase, putative 0.0112 0.0568 0.1338
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0027 0.0398
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0443 0.245 0.2844
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0019 0.004 0.0139
Loa Loa (eye worm) hypothetical protein 0.0443 0.245 0.4646
Trichomonas vaginalis helicase, putative 0.0014 0.001 0.0024
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0049 0.021 0.3672
Leishmania major cytochrome p450-like protein 0.0019 0.004 0.0068
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.024 0.0279
Echinococcus granulosus tm gpcr rhodopsin 0.0962 0.5399 0.6353
Plasmodium vivax ferredoxin, putative 0.0024 0.0068 0.1201
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0041 0.0164 0.0164
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0019 0.004 0.0139
Brugia malayi Dopamine receptor 0.0055 0.024 0.0456
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0111 0.0262
Echinococcus granulosus tumor protein p63 0.0738 0.4126 0.4854
Schistosoma mansoni biogenic amine receptor 0.0055 0.024 0.0279
Entamoeba histolytica hypothetical protein 0.0039 0.0152 0.2667
Entamoeba histolytica bifunctional short chain isoprenyl diphosphate synthase, putative 0.0028 0.0091 0.159
Loa Loa (eye worm) hypothetical protein 0.0265 0.1436 0.2723
Trichomonas vaginalis glucosylceramidase, putative 0.0564 0.3137 0.7385
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0019 0.004 0.0139
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.024 0.0283
Loa Loa (eye worm) hypothetical protein 0.0013 0.0001 0.0001
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0125 0.0642 0.0755
Echinococcus granulosus ecdysone induced protein 78C 0.094 0.5274 0.6204
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0041 0.0164 0.0164
Echinococcus granulosus serotonin transporter 0.0265 0.1436 0.1689
Trichomonas vaginalis set domain proteins, putative 0.0261 0.1413 0.3327
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.024 0.024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0095 0.0224
Brugia malayi Nuclear hormone receptor family member nhr-40 0.094 0.5274 1
Trypanosoma brucei DNA polymerase eta, putative 0.0021 0.0049 0.0088
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0039 0.0152 0.0318
Brugia malayi hypothetical protein 0.0045 0.0185 0.0351
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0141 0.0141
Echinococcus granulosus decaprenyl diphosphate synthase subunit 1 0.0028 0.0091 0.0107
Onchocerca volvulus 0.094 0.5274 1
Schistosoma mansoni hypothetical protein 0.0017 0.0027 0.0032
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.0173
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0443 0.245 0.2883
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0019 0.004 0.0139
Leishmania major C-8 sterol isomerase-like protein 0.0807 0.4518 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0352 0.0667
Plasmodium falciparum octaprenyl pyrophosphate synthase 0.0028 0.0091 0.1595
Mycobacterium ulcerans DNA polymerase IV 0.0021 0.0049 0.0172
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0019 0.004 0.0139
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Trichomonas vaginalis glucosylceramidase, putative 0.0564 0.3137 0.7385
Trypanosoma cruzi cytochrome P450, putative 0.0038 0.0148 0.0309
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0016 0.002 0.002
Loa Loa (eye worm) intermediate filament protein 0.0059 0.0264 0.0501
Leishmania major cytochrome p450-like protein 0.0019 0.004 0.0068
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0045 0.0185 0.0218
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0019 0.004 0.0139
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0152 0.0771
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0019 0.004 0.0197
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.024 0.0279
Schistosoma mansoni DNA polymerase eta 0.0021 0.0049 0.0057
Brugia malayi neuropeptide F receptor 0.0055 0.024 0.0456
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0017 0.0023 0.0027
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0496 0.2753 0.2753
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0037 0.0138 0.2014
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0022 0.0054 0.0103
Trypanosoma cruzi solanesyl-diphosphate synthase 0.0028 0.0091 0.0181
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Plasmodium falciparum ferredoxin, putative 0.0024 0.0068 0.1201
Echinococcus granulosus tyrosine kinase 0.0037 0.0141 0.0166
Brugia malayi Phospholipase D. Active site motif family protein 0.0021 0.005 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0027 0.0027
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0807 0.4518 0.8566
Brugia malayi hypothetical protein 0.011 0.0557 0.1056
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0564 0.3137 0.5948
Echinococcus granulosus allatostatin A receptor 0.0055 0.024 0.0283
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.024 0.0283
Brugia malayi Dopamine receptor protein 1 0.0055 0.024 0.0456
Echinococcus multilocularis lipoxygenase domain containing protein 0.0043 0.0174 0.0174
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0256 0.1387 0.7058
Loa Loa (eye worm) hypothetical protein 0.0807 0.4518 0.8566
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Echinococcus granulosus Adrenodoxin mitochondrial 0.0024 0.0068 0.008
Schistosoma mansoni loxhd1 0.0043 0.0174 0.0201
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0081 0.0388 0.0388
Schistosoma mansoni sodium/chloride dependent transporter 0.0045 0.0185 0.0215
Toxoplasma gondii adrenodoxin-type ferredoxin, putative 0.0024 0.0068 0.0998
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.024 0.0456
Brugia malayi CXXC zinc finger family protein 0.0063 0.0286 0.0543
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus granulosus tyrosine protein kinase HCK 0.0033 0.0118 0.0139
Mycobacterium ulcerans aldehyde dehydrogenase 0.0133 0.0684 0.2448
Loa Loa (eye worm) hypothetical protein 0.0028 0.0087 0.0164
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0049 0.021 0.0445
Loa Loa (eye worm) hypothetical protein 0.0027 0.0085 0.0161
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.0341 0.0396
Echinococcus granulosus death domain containing protein 0.0016 0.0019 0.0023
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.094 0.5274 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0109 0.0128
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0123 0.0143
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0145 0.0754 0.27
Onchocerca volvulus 0.0055 0.024 0.0456
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.094 0.5274 0.5274
Echinococcus multilocularis phospholipase d3 0.0021 0.005 0.005
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.024 0.024
Trypanosoma brucei electron transfer protein, putative 0.0024 0.0068 0.0131
Leishmania major hypothetical protein, conserved 0.0028 0.0087 0.0172
Brugia malayi nuclear receptor NHR-88 0.094 0.5274 1
Brugia malayi Pre-SET motif family protein 0.0034 0.0123 0.0234
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Echinococcus multilocularis allatostatin A receptor 0.0055 0.024 0.024
Brugia malayi Adrenodoxin-like protein, mitochondrial precursor, putative 0.0024 0.0068 0.0129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.019
Schistosoma mansoni cpg binding protein 0.0066 0.0307 0.0356
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0045 0.0185 0.0185
Schistosoma mansoni opsin-like receptor 0.0055 0.024 0.0279
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.024 0.0283
Echinococcus multilocularis para nitrobenzyl esterase 0.0013 0.0001 0.0001
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0759 0.4248 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0036 0.0135 0.0135
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0019 0.004 0.0139
Echinococcus multilocularis lamin 0.0059 0.0264 0.0264
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0145 0.0754 0.3833
Loa Loa (eye worm) ubiquitin conjugating enzyme protein 13 0.0042 0.0166 0.0314
Schistosoma mansoni amine GPCR 0.0055 0.024 0.0279
Trichomonas vaginalis glucosylceramidase, putative 0.037 0.2034 0.4788
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0019 0.004 0.0197
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0496 0.2753 0.3195
Schistosoma mansoni nuclear receptor 0.0443 0.245 0.2844
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni multidrug resistance protein 0.0014 0.0009 0.0011
Onchocerca volvulus 0.0055 0.024 0.0456
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.024 0.0283
Echinococcus granulosus tyrosine protein kinase Fyn 0.0041 0.0164 0.0193
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0019 0.0023
Trypanosoma brucei unspecified product 0.0021 0.0049 0.0088
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0019 0.004 0.0197
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0083 0.0404 0.0766
Plasmodium falciparum mitochondrial cardiolipin synthase, putative 0.0018 0.0032 0.0564
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0138 0.0324
Echinococcus multilocularis g protein coupled receptor 0.0055 0.024 0.024
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.014 0.0266
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0443 0.245 0.4646
Loa Loa (eye worm) cytochrome P450 family protein 0.0061 0.0277 0.0526
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.0341 0.0401
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.094 0.5274 0.612
Echinococcus granulosus GPCR family 2 0.0017 0.0027 0.0032
Echinococcus multilocularis phospholipase D 0.01 0.0496 0.0496
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0027 0.004
Brugia malayi G-protein coupled receptor 0.0055 0.024 0.0456
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0044 0.0178 0.0376
Trichomonas vaginalis spcc417.12 protein, putative 0.0013 0.0001 0.0002
Schistosoma mansoni sodium/chloride dependent transporter 0.0265 0.1436 0.1666
Echinococcus multilocularis conserved hypothetical protein 0.0756 0.4229 0.4229
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0027 0.0479
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0123 0.0123
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.024 0.0283
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0024 0.0068 0.0343
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Brugia malayi intermediate filament protein 0.0059 0.0264 0.0501
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0019 0.004 0.0197
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.024 0.0279
Brugia malayi follicle stimulating hormone receptor 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Loa Loa (eye worm) hypothetical protein 0.0017 0.0027 0.0051
Loa Loa (eye worm) phosphatidylinositol 3 0.0049 0.021 0.0397
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.0341 0.0646
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0152 0.0179
Brugia malayi Nuclear hormone receptor family member nhr-31 0.094 0.5274 1
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0049 0.021 0.021
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.094 0.5274 0.6204
Echinococcus multilocularis ecdysone induced protein 78C 0.094 0.5274 0.5274
Echinococcus multilocularis neuroligin 0.0013 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0059 0.0264 0.0501
Mycobacterium leprae conserved hypothetical protein 0.0039 0.0152 0.3095
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0019 0.004 0.0139
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.024 0.024
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0017 0.0025 0.0025
Toxoplasma gondii phospholipase D active site domain-containing protein 0.0039 0.0153 0.2237
Leishmania major hypothetical protein, conserved 0.0039 0.0152 0.0318
Brugia malayi Dopamine receptor protein 2 0.0055 0.024 0.0456
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0019 0.004 0.0139
Echinococcus granulosus potassium voltage gated channel subfamily H 0.004 0.0158 0.0186
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0152 0.0318
Onchocerca volvulus 0.0045 0.0185 0.0351
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0185 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0152 0.0358
Brugia malayi putative neuropeptide receptor 0.0055 0.024 0.0456
Echinococcus granulosus RUN 0.0043 0.0174 0.0204
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.001 0.0024
Echinococcus granulosus phospholipase d3 0.0021 0.005 0.0059
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0041 0.0164 0.0164
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0027 0.0051
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0045 0.0185 0.0215
Brugia malayi Nuclear hormone receptor family member nhr-1 0.094 0.5274 1
Echinococcus multilocularis multidrug resistance associated protein 7 0.0014 0.0009 0.0009
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0047 0.0047
Echinococcus multilocularis decaprenyl diphosphate synthase subunit 1 0.0028 0.0091 0.0091
Trypanosoma cruzi DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0017 0.0023 0.0055
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.004 0.0578
Brugia malayi hypothetical protein 0.0055 0.024 0.0456
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0038 0.0088
Echinococcus granulosus prenyl decaprenyl diphosphate synthase 0.0028 0.0091 0.0107
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.094 0.5274 0.5274
Echinococcus multilocularis Protein lozenge 0.006 0.0273 0.0273
Onchocerca volvulus 0.0013 0.0001 0.0001
Loa Loa (eye worm) beta-lactamase 0.0039 0.0152 0.0289
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0016 0.002 0.0024
Echinococcus multilocularis ubiquitin specific protease 41 0.0044 0.0178 0.0178
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0019 0.004 0.0197
Schistosoma mansoni voltage-gated potassium channel 0.0044 0.0179 0.0208
Schistosoma mansoni biogenic amine receptor 0.0055 0.024 0.0279
Loa Loa (eye worm) hypothetical protein 0.0035 0.0128 0.0242
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.024 0.0279
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0045 0.0185 0.0215
Brugia malayi nuclear receptor RXR 0.0496 0.2753 0.522
Loa Loa (eye worm) hypothetical protein 0.0045 0.0185 0.0351
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0016
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0017 0.0023 0.0032
Loa Loa (eye worm) hypothetical protein 0.0496 0.2753 0.522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0049 0.021 0.0493
Loa Loa (eye worm) hypothetical protein 0.094 0.5274 1
Entamoeba histolytica ATP-binding cassette protein, putative 0.0014 0.0009 0.0158
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0081 0.019
Mycobacterium ulcerans oxygenase 0.0024 0.0068 0.0242
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0049 0.0088
Loa Loa (eye worm) SRC-1 0.0041 0.0164 0.0311
Echinococcus granulosus geranylgeranyl pyrophosphate synthase 0.0028 0.0091 0.0107
Loa Loa (eye worm) hypothetical protein 0.0055 0.024 0.0456
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0016 0.002 0.0024

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 12 nM Inhibitory activity against HIV-1 protease ChEMBL. 14643311
Ki (binding) = 12 nM Inhibitory activity against HIV-1 protease ChEMBL. 14643311

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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