TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 325.358 | Formula: C19H19NO4
H donors: 2 H acceptors: 3 LogP: 3.74 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: CCN(c1ccc(cc1)/C=C\1/Oc2c(C1=O)ccc(c2O)O)CC
InChi: 1S/C19H19NO4/c1-3-20(4-2)13-7-5-12(6-8-13)11-16-17(22)14-9-10-15(21)18(23)19(14)24-16/h5-11,21,23H,3-4H2,1-2H3/b16-11+
InChiKey: FIJOFUUQGBYKPA-LFIBNONCSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)	Chorismate synthase	Starlite/ChEMBL	References
Escherichia coli	5-enolpyruvylshikimate-3-phosphate synthetase	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Chlamydia trachomatis	phosphoshikimate 1-carboxyl vinyltransferase	Get druggable targets OG5_127183	All targets in OG5_127183
Plasmodium vivax	chorismate synthase	Get druggable targets OG5_128304	All targets in OG5_128304
Mycobacterium tuberculosis	3-dehydroquinate synthase AroB	Get druggable targets OG5_127183	All targets in OG5_127183
Candida albicans	Chorismate synthase	Get druggable targets OG5_128304	All targets in OG5_128304
Mycobacterium ulcerans	chorismate synthase	Get druggable targets OG5_128304	All targets in OG5_128304
Mycobacterium leprae	3-dehydroquinate synthase AroB	Get druggable targets OG5_127183	All targets in OG5_127183
Neospora caninum	3-dehydroquinate synthase (EC 4.2.3.4), related	Get druggable targets OG5_127183	All targets in OG5_127183
Plasmodium falciparum	chorismate synthase	Get druggable targets OG5_128304	All targets in OG5_128304
Plasmodium knowlesi	chorismate synthase, putative	Get druggable targets OG5_128304	All targets in OG5_128304
Toxoplasma gondii	chorismate synthase, putative	Get druggable targets OG5_128304	All targets in OG5_128304
Mycobacterium ulcerans	3-dehydroquinate synthase	Get druggable targets OG5_127183	All targets in OG5_127183
Mycobacterium leprae	Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase).	Get druggable targets OG5_128304	All targets in OG5_128304
Candida albicans	chorismate synthase	Get druggable targets OG5_128304	All targets in OG5_128304
Mycobacterium leprae	probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS	Get druggable targets OG5_127183	All targets in OG5_127183
Chlamydia trachomatis	dehyroquinate synthase	Get druggable targets OG5_127183	All targets in OG5_127183
Chlamydia trachomatis	chorismate synthase	Get druggable targets OG5_128304	All targets in OG5_128304
Candida albicans	similar to S. cerevisiae ARO1 pentafunctional aromatic amino acid family biosynthesis protein	Get druggable targets OG5_127183	All targets in OG5_127183
Neospora caninum	Chorismate synthase (EC 4.2.3.5), related	Get druggable targets OG5_128304	All targets in OG5_128304
Plasmodium berghei	chorismate synthase, putative	Get druggable targets OG5_128304	All targets in OG5_128304
Toxoplasma gondii	shikimate dehydrogenase substrate binding domain-containing protein	Get druggable targets OG5_127183	All targets in OG5_127183
Plasmodium yoelii	chorismate synthase, putative	Get druggable targets OG5_128304	All targets in OG5_128304
Candida albicans	similar to S. cerevisiae ARO1 pentafunctional aromatic amino acid family biosynthesis protein	Get druggable targets OG5_127183	All targets in OG5_127183
Mycobacterium ulcerans	3-phosphoshikimate 1-carboxyvinyltransferase	Get druggable targets OG5_127183	All targets in OG5_127183
Mycobacterium tuberculosis	3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS)	Get druggable targets OG5_127183	All targets in OG5_127183
Schistosoma mansoni	3-dehydroquinate synthase	Get druggable targets OG5_127183	All targets in OG5_127183
Mycobacterium tuberculosis	Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase)	Get druggable targets OG5_128304	All targets in OG5_128304

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	cAMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Mycobacterium ulcerans	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.0218	0.5421	0.5414
Schistosoma mansoni	3-dehydroquinate synthase	0.0139	0.3342	0.3342
Trichomonas vaginalis	high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Chlamydia trachomatis	chorismate synthase	0.0216	0.536	0.3031
Echinococcus granulosus	Immunoglobulin	0.0025	0.0355	0.0355
Trichomonas vaginalis	cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0036	0.0641	0.0641
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0045	0.086	0.086
Loa Loa (eye worm)	TK protein kinase	0.0036	0.0641	0.0509
Plasmodium falciparum	bifunctional dihydrofolate reductase-thymidylate synthase	0.015	0.3631	0.6767
Brugia malayi	SRC-1	0.0045	0.086	0.086
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0025	0.0355	0.0355
Leishmania major	dihydrofolate reductase-thymidylate synthase	0.015	0.3631	1
Trichomonas vaginalis	cone cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus multilocularis	tyrosine protein kinase Blk	0.004	0.0752	0.0752
Plasmodium vivax	bifunctional dihydrofolate reductase-thymidylate synthase, putative	0.015	0.3631	0.6767
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0045	0.086	0.086
Echinococcus multilocularis	dihydrofolate reductase	0.0392	1	1
Loa Loa (eye worm)	TK protein kinase	0.0117	0.2776	0.2674
Loa Loa (eye worm)	hypothetical protein	0.0029	0.046	0.0326
Trichomonas vaginalis	cAMP-specific phosphodiesterase, putative	0.0017	0.0139	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0548	0.0415
Echinococcus granulosus	dihydrofolate reductase	0.0392	1	1
Trichomonas vaginalis	cGMP-dependent 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus multilocularis	dual 3',5' cyclic AMP and GMP phosphodiesterase	0.0017	0.0139	0.0139
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0117	0.2776	0.2776
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.0114	0.2688	0.2688
Schistosoma mansoni	nephrin	0.0029	0.0443	0.0443
Trichomonas vaginalis	cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	twitchin	0.0029	0.0443	0.0443
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0025	0.0355	0.0355
Echinococcus granulosus	fibroblast growth factor receptor 4	0.0114	0.2688	0.2688
Trichomonas vaginalis	calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0025	0.0355	0.0355
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0355	0.0219
Echinococcus granulosus	cAMP and cAMP inhibited cGMP 3'5' cyclic	0.0152	0.3685	0.3685
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0045	0.086	0.086
Echinococcus multilocularis	Immunoglobulin	0.0025	0.0355	0.0355
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0045	0.086	0.086
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0045	0.086	0.086
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0548	0.0415
Trichomonas vaginalis	calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.0114	0.2688	0.2688
Trichomonas vaginalis	cGMP-dependent 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	neuroglian	0.0029	0.0443	0.0443
Trichomonas vaginalis	calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0355	0.0219
Trypanosoma cruzi	dihydrofolate reductase-thymidylate synthase	0.015	0.3631	1
Entamoeba histolytica	protein kinase, putative	0.0036	0.0641	0.5
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0045	0.086	0.086
Chlamydia trachomatis	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.0218	0.5421	0.3122
Trichomonas vaginalis	calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0045	0.086	0.086
Trichomonas vaginalis	cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Trichomonas vaginalis	rod cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Mycobacterium tuberculosis	3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS)	0.0139	0.3342	0.3333
Loa Loa (eye worm)	TK protein kinase	0.004	0.0752	0.0621
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.004	0.0752	0.0752
Loa Loa (eye worm)	hypothetical protein	0.0147	0.356	0.3469
Echinococcus multilocularis	cAMP and cAMP inhibited cGMP 3',5' cyclic	0.0152	0.3685	0.3685
Trichomonas vaginalis	cAMP-specific phosphodiesterase, putative	0.0017	0.0139	1
Chlamydia trachomatis	dihydrofolate reductase	0.0392	1	1
Echinococcus granulosus	tyrosine kinase	0.004	0.0752	0.0752
Brugia malayi	protein-tyrosine kinase	0.004	0.0752	0.0752
Mycobacterium ulcerans	dihydrofolate reductase DfrA	0.0392	1	1
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0045	0.086	0.086
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0045	0.086	0.086
Schistosoma mansoni	tyrosine kinase	0.0114	0.2688	0.2688
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0355	0.0219
Trichomonas vaginalis	high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Mycobacterium ulcerans	3-dehydroquinate synthase	0.0139	0.3342	0.3333
Trichomonas vaginalis	cAMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Toxoplasma gondii	shikimate dehydrogenase substrate binding domain-containing protein	0.0357	0.9074	1
Trichomonas vaginalis	cGMP-inhibited 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0045	0.086	0.086
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0045	0.086	0.086
Brugia malayi	hypothetical protein	0.0025	0.0355	0.0355
Mycobacterium leprae	probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS	0.0357	0.9074	0.9072
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.0114	0.2688	0.2688
Toxoplasma gondii	bifunctional dihydrofolate reductase-thymidylate synthase	0.015	0.3631	0.3993
Brugia malayi	Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative	0.0152	0.3685	0.3685
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0045	0.086	0.086
Trichomonas vaginalis	rod cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	defective proboscis extension response	0.0025	0.0355	0.0355
Trichomonas vaginalis	conserved hypothetical protein	0.0017	0.0139	1
Trichomonas vaginalis	high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Mycobacterium ulcerans	chorismate synthase	0.0216	0.536	0.5354
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0355	0.0219
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0045	0.086	0.086
Mycobacterium leprae	DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE)	0.0392	1	1
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0025	0.0355	0.0355
Schistosoma mansoni	cell adhesion molecule	0.0029	0.046	0.046
Plasmodium vivax	chorismate synthase	0.0216	0.536	1
Trichomonas vaginalis	cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0033	0.0552	0.0419
Trichomonas vaginalis	cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Trichomonas vaginalis	cGMP-dependent 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0029	0.046	0.046
Trichomonas vaginalis	high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Loa Loa (eye worm)	dihydrofolate reductase	0.0392	1	1
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0045	0.086	0.086
Schistosoma mansoni	camp/cgmp cyclic nucleotide phosphodiesterase	0.0017	0.0139	0.0139
Echinococcus multilocularis	Immunoglobulin	0.0025	0.0355	0.0355
Schistosoma mansoni	dihydrofolate reductase	0.0392	1	1
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0045	0.086	0.086
Trichomonas vaginalis	rod cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Trichomonas vaginalis	cone cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Plasmodium falciparum	chorismate synthase	0.0216	0.536	1
Brugia malayi	Fibronectin type III domain containing protein	0.0025	0.0355	0.0355
Mycobacterium tuberculosis	Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase)	0.0392	1	1
Treponema pallidum	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.0218	0.5421	0.5
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0033	0.0552	0.0552
Loa Loa (eye worm)	hypothetical protein	0.0135	0.3235	0.314
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0045	0.086	0.086
Echinococcus granulosus	roundabout 2	0.0033	0.0548	0.0548
Trichomonas vaginalis	calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Chlamydia trachomatis	phosphoshikimate 1-carboxyl vinyltransferase	0.0357	0.9074	0.8609
Loa Loa (eye worm)	SRC-1	0.0045	0.086	0.0731
Echinococcus multilocularis	roundabout 2	0.0033	0.0548	0.0548
Echinococcus granulosus	dual 3'5' cyclic AMP and GMP phosphodiesterase	0.0017	0.0139	0.0139
Mycobacterium leprae	Chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase).	0.0106	0.2486	0.2475
Schistosoma mansoni	cgmp-dependent 35-cyclic phosphodiesterase	0.0017	0.0139	0.0139
Brugia malayi	Dihydrofolate reductase	0.0392	1	1
Brugia malayi	3'5'-cyclic nucleotide phosphodiesterase family protein	0.0017	0.0139	0.0139
Trypanosoma brucei	dihydrofolate reductase-thymidylate synthase	0.015	0.3631	1
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0355	0.0219
Mycobacterium leprae	3-dehydroquinate synthase AroB	0.0139	0.3342	0.3333
Schistosoma mansoni	tyrosine kinase	0.0045	0.086	0.086
Trichomonas vaginalis	high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0037	0.066	0.066
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0037	0.066	0.066
Schistosoma mansoni	vesicular amine transporter	0.0025	0.0355	0.0355
Echinococcus granulosus	tyrosine protein kinase HCK	0.0036	0.0641	0.0641
Trichomonas vaginalis	calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1
Schistosoma mansoni	tyrosine kinase	0.0045	0.086	0.086
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.004	0.0752	0.0752
Toxoplasma gondii	chorismate synthase, putative	0.0216	0.536	0.5901
Trichomonas vaginalis	cGMP-specific 3,5-cyclic phosphodiesterase, putative	0.0017	0.0139	1
Mycobacterium ulcerans	3-phosphoshikimate 1-carboxyvinyltransferase	0.0357	0.9074	0.9072
Echinococcus granulosus	tyrosine protein kinase Blk	0.004	0.0752	0.0752
Wolbachia endosymbiont of Brugia malayi	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.0218	0.5421	0.5
Mycobacterium tuberculosis	3-dehydroquinate synthase AroB	0.0139	0.3342	0.3333
Echinococcus multilocularis	neuroglian	0.0029	0.0443	0.0443
Echinococcus multilocularis	tyrosine protein kinase Srms	0.004	0.0752	0.0752
Loa Loa (eye worm)	hypothetical protein	0.0025	0.0355	0.0219
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0045	0.086	0.086
Mycobacterium tuberculosis	Probable chorismate synthase AroF (5-enolpyruvylshikimate-3-phosphate phospholyase)	0.0106	0.2486	0.2475
Trichomonas vaginalis	cAMP/cGMP cyclic nucleotide phosphodiesterase, putative	0.0017	0.0139	1

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 8.5 uM	Inhibitory concentration against Streptococcus pneumoniae chorismate synthase	ChEMBL.	12565943
IC50 (binding)	= 8.5 uM	Inhibitory concentration against Streptococcus pneumoniae chorismate synthase	ChEMBL.	12565943
Ki (binding)	= 0.65 uM	Competitive inhibitory activity of the compound was determined with respect to EPSP (5-enolpyruvylshikimate- 3-phosphate) synthase	ChEMBL.	12565943
Ki (binding)	= 0.65 uM	Competitive inhibitory activity of the compound was determined with respect to EPSP (5-enolpyruvylshikimate- 3-phosphate) synthase	ChEMBL.	12565943
Ki (binding)	= 1.7 uM	Non-competitive inhibitory activity of the compound was determined with respect to cofactor FMN	ChEMBL.	12565943
Km (binding)	= 0.08 uM	Michaelis-mention constant of the compound for cofactor FMN was evaluated	ChEMBL.	12565943
Km (binding)	= 30 uM	Michaelis-mention constant of the compound for EPSP (5-enolpyruvylshikimate- 3-phosphate) synthase was evaluated	ChEMBL.	12565943
Km (binding)	= 30 uM	Michaelis-mention constant of the compound for EPSP (5-enolpyruvylshikimate- 3-phosphate) synthase was evaluated	ChEMBL.	12565943

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL334500

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 236259