TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 435.515 | Formula: C25H29N3O4
H donors: 3 H acceptors: 3 LogP: 3.98 Rotable bonds: 13
Rule of 5 violations (Lipinski): 1
SMILES: O=C[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H]([C@H](CC)C)NC(=O)OCc1ccccc1
InChi: 1S/C25H29N3O4/c1-3-17(2)23(28-25(31)32-16-18-9-5-4-6-10-18)24(30)27-20(15-29)13-19-14-26-22-12-8-7-11-21(19)22/h4-12,14-15,17,20,23,26H,3,13,16H2,1-2H3,(H,27,30)(H,28,31)/t17?,20-,23+/m1/s1
InChiKey: BUXZFLJETAQWPU-KLXHUVPASA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0103	0.2406	0.5489
Echinococcus multilocularis	isocitrate dehydrogenase	0.0015	0.0176	0.0173
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Echinococcus multilocularis	irregular chiasm roughest protein immunoglobulin set domain containing protein	0.0099	0.2327	0.2325
Brugia malayi	Cathepsin L-like precursor	0.0032	0.0599	0.1365
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.006	0.131	1
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0103	0.2406	0.2404
Brugia malayi	excitatory GABA receptor EXP-1A	0.0103	0.2406	0.5489
Onchocerca volvulus		0.0032	0.0599	0.2375
Plasmodium vivax	unspecified product	0.0019	0.0264	0.4322
Entamoeba histolytica	cysteine proteinase, putative	0.0023	0.037	0.2886
Echinococcus granulosus	Immunoglobulin	0.0099	0.2327	0.2325
Echinococcus multilocularis	Immunoglobulin	0.0085	0.196	0.1958
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0023	0.037	0.0885
Onchocerca volvulus		0.0047	0.0992	0.4034
Brugia malayi	Cathepsin L-like precursor	0.0032	0.0599	0.1365
Toxoplasma gondii	isocitrate dehydrogenase	0.0015	0.0176	0.1098
Echinococcus granulosus	low density lipoprotein receptor ldl	0.008	0.1839	0.1836
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0103	0.2406	0.5789
Brugia malayi	cathepsin L-like precursor	0.0023	0.037	0.0845
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Onchocerca volvulus		0.0028	0.0498	0.1952
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Onchocerca volvulus		0.0023	0.037	0.1412
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.001	0.0036	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0165	0.4018	0.967
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0032	0.0599	0.0596
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0103	0.2406	0.5489
Brugia malayi	Papain family cysteine protease containing protein	0.0019	0.0264	0.0602
Loa Loa (eye worm)	neuronal acetylcholine receptor protein	0.0047	0.0992	0.2382
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0103	0.2406	0.5789
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Echinococcus granulosus	neuroglian	0.0085	0.196	0.1958
Loa Loa (eye worm)	hypothetical protein	0.0023	0.037	0.0885
Echinococcus multilocularis	gamma aminobutyric acid receptor subunit	0.0047	0.0992	0.0989
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0019	0.0264	0.0255
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0103	0.2406	0.5789
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0103	0.2406	0.2404
Brugia malayi	Cation transporter family protein	0.0103	0.2406	0.5489
Schistosoma mansoni	NADP-specific isocitrate dehydrogenase	0.0015	0.0176	0.0167
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.001	0.0036	0.0451
Brugia malayi	cathepsin B-like cysteine proteinase	0.0171	0.4155	0.9476
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0498	0.1137
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0085	0.196	0.1953
Onchocerca volvulus		0.0055	0.1195	0.4891
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0103	0.2406	0.5489
Echinococcus granulosus	cathepsin L	0.001	0.0036	0.0033
Trypanosoma cruzi	cysteine peptidase, putative	0.0032	0.0599	0.1422
Schistosoma mansoni	nAChR subunit	0.0047	0.0992	0.0984
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0103	0.2406	0.24
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Schistosoma mansoni	cathepsin F (C01 family)	0.0032	0.0599	0.059
Entamoeba histolytica	cysteine proteinase, putative	0.0019	0.0264	0.1968
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Papain family cysteine protease containing protein	0.0032	0.0599	0.1365
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0023	0.037	0.2627
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Echinococcus multilocularis	cathepsin b	0.0171	0.4155	0.4153
Brugia malayi	fibroinase precursor	0.001	0.0036	0.0081
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.0103	0.2406	0.5489
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0103	0.2406	0.5489
Entamoeba histolytica	cysteine protease, putative	0.0032	0.0599	0.4854
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0171	0.4155	0.415
Onchocerca volvulus		0.0103	0.2406	1
Onchocerca volvulus		0.0103	0.2406	1
Onchocerca volvulus		0.0032	0.0599	0.2375
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0103	0.2406	0.2404
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0099	0.2327	0.5307
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0015	0.0176	0.0173
Brugia malayi	Papain family cysteine protease containing protein	0.001	0.0036	0.0081
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0047	0.0992	0.2262
Schistosoma mansoni	hypothetical protein	0.0099	0.2327	0.232
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Brugia malayi	Cathepsin L-like precursor	0.0032	0.0599	0.1365
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0103	0.2406	0.24
Brugia malayi	Cathepsin L-like precursor	0.0032	0.0599	0.1365
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.001	0.0036	0.0027
Echinococcus granulosus	nAChR subunit	0.0103	0.2406	0.2404
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0103	0.2406	0.5489
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Echinococcus multilocularis	Immunoglobulin	0.0185	0.4506	0.4504
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0019	0.0264	0.0255
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0032	0.0599	1
Loa Loa (eye worm)	hypothetical protein	0.001	0.0036	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Entamoeba histolytica	cysteine proteinase, putative	0.0032	0.0599	0.4854
Schistosoma mansoni	cell adhesion molecule	0.0085	0.196	0.1953
Loa Loa (eye worm)	hypothetical protein	0.001	0.0036	0.0079
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Loa Loa (eye worm)	GABA receptor subunit	0.0055	0.1195	0.2872
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Schistosoma mansoni	nAChR subunit	0.0047	0.0992	0.0984
Brugia malayi	Cathepsin L-like precursor	0.0009	0.0009	0.0021
Schistosoma mansoni	acetylcholine receptor subunit beta	0.0047	0.0992	0.0984
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Echinococcus granulosus	cpg binding protein	0.003	0.0539	0.0537
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0103	0.2406	0.5489
Brugia malayi	cathepsin L-like cysteine proteinase	0.001	0.0036	0.0081
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0103	0.2406	0.2404
Brugia malayi	Cation transporter family protein	0.0103	0.2406	0.5489
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0085	0.196	0.1958
Giardia lamblia	Cathepsin B precursor	0.006	0.131	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Brugia malayi	Papain family cysteine protease containing protein	0.001	0.0036	0.0081
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Isocitrate dehydrogenase	0.0015	0.0176	0.04
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0047	0.0992	0.0989
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0019	0.0264	0.0779
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0103	0.2406	0.5489
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0009	0.0015
Trypanosoma brucei	cysteine peptidase C (CPC)	0.006	0.131	1
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0171	0.4155	1
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.001	0.0036	0.0079
Plasmodium vivax	isocitrate dehydrogenase [NADP], mitochondrial, putative	0.0015	0.0176	0.2824
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Onchocerca volvulus		0.0032	0.0599	0.2375
Brugia malayi	isocitrate dehydrogenase	0.0015	0.0176	0.04
Echinococcus multilocularis	cathepsin L	0.001	0.0036	0.0033
Echinococcus granulosus	nephrin	0.0099	0.2327	0.2325
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0059	0.1303	0.1295
Echinococcus multilocularis	dnaJ subfamily B	0.0399	1	1
Trypanosoma cruzi	cruzipain precursor, putative	0.0032	0.0599	0.1422
Echinococcus multilocularis	hemicentin 1	0.008	0.1839	0.1836
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0103	0.2406	0.5789
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Giardia lamblia	Cathepsin B precursor	0.006	0.131	1
Echinococcus multilocularis	cathepsin b	0.0171	0.4155	0.4153
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0103	0.2406	0.2404
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Echinococcus multilocularis	low density lipoprotein receptor (ldl)	0.008	0.1839	0.1836
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0019	0.0264	0.4054
Echinococcus multilocularis	roundabout 2	0.0085	0.196	0.1958
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0085	0.196	0.1953
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.001	0.0036	0.0451
Brugia malayi	Acetylcholine receptor protein, alpha-like chain 1 precursor	0.0047	0.0992	0.2262
Onchocerca volvulus	Putative titin	0.008	0.1839	0.7605
Echinococcus multilocularis	cpg binding protein	0.003	0.0539	0.0537
Loa Loa (eye worm)	hypothetical protein	0.0171	0.4155	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0032	0.0599	0.0596
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0085	0.196	0.1958
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.001	0.0036	0.0451
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0015	0.0176	0.0416
Trypanosoma cruzi	cysteine protease, putative	0.0019	0.0264	0.0615
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0103	0.2406	0.5789
Echinococcus multilocularis	conserved hypothetical protein	0.0099	0.2327	0.2325
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.001	0.0036	0.0027
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0103	0.2406	0.5489
Echinococcus multilocularis	geminin	0.0165	0.4014	0.4013
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0009	0.0009	0.0021
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.001	0.0036	0.0027
Plasmodium vivax	vivapain-3	0.0019	0.0264	0.4322
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.001	0.0036	0.0451
Entamoeba histolytica	hypothetical protein	0.0055	0.1195	1
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.008	0.1839	0.1831
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0085	0.196	0.447
Onchocerca volvulus		0.008	0.1839	0.7605
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0099	0.2327	0.5307
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Loa Loa (eye worm)	hypothetical protein	0.0023	0.037	0.0885
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0055	0.1195	0.2726
Brugia malayi	hypothetical protein	0.0085	0.196	0.447
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.001	0.0036	0.0027
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Brugia malayi	Fibronectin type III domain containing protein	0.0085	0.196	0.447
Loa Loa (eye worm)	ACC-1 protein	0.0103	0.2406	0.5789
Onchocerca volvulus		0.0032	0.0599	0.2375
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0019	0.0264	0.0255
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0047	0.0992	0.2382
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0103	0.2406	0.2404
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0009	0.0015
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0103	0.2406	0.24
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.006	0.131	0.3137
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Cathepsin L-like precursor	0.0023	0.037	0.0845
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0055	0.1195	0.1187
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.001	0.0036	0.0451
Onchocerca volvulus		0.008	0.1839	0.7605
Echinococcus granulosus	nAChR subunit	0.0055	0.1195	0.1193
Schistosoma mansoni	cathepsin B (C01 family)	0.001	0.0036	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.001	0.0036	0.0451
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0055	0.1195	0.2726
Brugia malayi	hypothetical protein	0.0047	0.0992	0.2262
Echinococcus multilocularis	cathepsin L cysteine protease	0.0032	0.0599	0.0596
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Loa Loa (eye worm)	LGC-31 protein	0.0103	0.2406	0.5789
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.001	0.0036	0.0451
Schistosoma mansoni	cpg binding protein	0.003	0.0539	0.0531
Plasmodium vivax	vivapain-1	0.0019	0.0264	0.4322
Trypanosoma cruzi	major cysteine proteinase, putative	0.001	0.0036	0.0064
Brugia malayi	cathepsin Z-like cysteine proteinase	0.001	0.0036	0.0081
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0099	0.2327	0.5597
Brugia malayi	Cathepsin L-like precursor	0.0032	0.0599	0.1365
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0047	0.0992	0.2262
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0032	0.0599	0.0596
Schistosoma mansoni	hypothetical protein	0.008	0.1839	0.1831
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0019	0.0264	0.1791
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0099	0.2327	0.5597
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0019	0.0264	0.0615
Trypanosoma cruzi	isocitrate dehydrogenase, putative	0.0015	0.0176	0.0402
Onchocerca volvulus		0.0047	0.0992	0.4034
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0103	0.2406	0.2404
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0047	0.0992	0.2262
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Onchocerca volvulus		0.0103	0.2406	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.0019	0.0264	0.1968
Echinococcus granulosus	twitchin	0.0085	0.196	0.1958
Brugia malayi	cathepsin L precursor	0.001	0.0036	0.0081
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Loa Loa (eye worm)	acetylcholine receptor protein	0.0047	0.0992	0.2382
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Echinococcus granulosus	cathepsin L	0.0019	0.0264	0.0261
Trypanosoma cruzi	major cysteine proteinase, putative	0.001	0.0036	0.0064
Entamoeba histolytica	cysteine proteinase, putative	0.0019	0.0264	0.1968
Onchocerca volvulus	Cathepsin L homolog	0.0032	0.0599	0.2375
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.006	0.131	1
Echinococcus multilocularis	neuroglian	0.0085	0.196	0.1958
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0176	0.0173
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Schistosoma mansoni	hypothetical protein	0.0399	1	1
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0176	0.0173
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0023	0.037	0.2627
Schistosoma mansoni	neurotransmitter gated ion channel	0.0047	0.0992	0.0984
Trypanosoma cruzi	cysteine proteinase, putative	0.0019	0.0264	0.0615
Brugia malayi	hypothetical protein	0.0047	0.0992	0.2262
Loa Loa (eye worm)	hypothetical protein	0.001	0.0036	0.0079
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.001	0.0036	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0103	0.2406	0.2404
Echinococcus multilocularis	nAChR subunit	0.0103	0.2406	0.2404
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0019	0.0264	0.0779
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0103	0.2406	0.5489
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0015	0.0176	0.0173
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Trypanosoma cruzi	cysteine peptidase, putative	0.0019	0.0264	0.0615
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Papain family cysteine protease containing protein	0.001	0.0036	0.0081
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Brugia malayi	cathepsin F-like cysteine proteinase	0.0009	0.0009	0.0021
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Schistosoma mansoni	nephrin	0.0085	0.196	0.1953
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0047	0.0992	0.0989
Plasmodium vivax	unspecified product	0.001	0.0036	0.0451
Schistosoma mansoni	hypothetical protein	0.0165	0.4014	0.4009
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Onchocerca volvulus		0.0032	0.0599	0.2375
Brugia malayi	cathepsin Z-like cysteine proteinase	0.001	0.0036	0.0081
Schistosoma mansoni	titin	0.008	0.1839	0.1831
Onchocerca volvulus	Cathepsin F homolog	0.0032	0.0599	0.2375
Loa Loa (eye worm)	fibroinase	0.0032	0.0599	0.1435
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Schistosoma mansoni	hypothetical protein	0.0165	0.4014	0.4009
Toxoplasma gondii	cathepsin CPL	0.0032	0.0599	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Trypanosoma cruzi	cysteine peptidase, putative	0.0032	0.0599	0.1422
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.001	0.0036	0.0451
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.001	0.0036	0.0081
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0032	0.0599	0.4419
Onchocerca volvulus		0.0047	0.0992	0.4034
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0085	0.196	0.447
Plasmodium falciparum	isocitrate dehydrogenase [NADP], mitochondrial	0.0015	0.0176	0.2486
Brugia malayi	Cathepsin L-like precursor	0.0023	0.037	0.0845
Echinococcus granulosus	glycine receptor subunit beta	0.0103	0.2406	0.2404
Echinococcus granulosus	roundabout 2	0.0085	0.196	0.1958
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Schistosoma mansoni	cathepsin C	0.001	0.0036	0.0027
Schistosoma mansoni	cathepsin S (C01 family)	0.001	0.0036	0.0027
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0103	0.2406	0.2404
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0103	0.2406	0.2404
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0047	0.0992	0.2262
Loa Loa (eye worm)	cathepsin B	0.006	0.131	0.3147
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0009	0.0009	0.0015
Loa Loa (eye worm)	cysteine protease	0.0032	0.0599	0.1435
Schistosoma mansoni	vesicular amine transporter	0.0085	0.196	0.1953
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.0171	0.4155	0.415
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.001	0.0036	0.0451
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0103	0.2406	0.5489
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0032	0.0599	0.0596
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0053	0.114	0.867
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.006	0.131	0.1302
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Schistosoma mansoni	hypothetical protein	0.0099	0.2327	0.232
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.001	0.0036	0.0027
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0103	0.2406	0.5489
Onchocerca volvulus	Netrin receptor homolog	0.008	0.1839	0.7605
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Cathepsin L-like precursor	0.0032	0.0599	0.1365
Mycobacterium tuberculosis	Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP)	0.0015	0.0176	0.5
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0103	0.2406	0.2404
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0103	0.2406	0.24
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.001	0.0036	0.0027
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Brugia malayi	Cation transporter family protein	0.0103	0.2406	0.5489
Onchocerca volvulus		0.008	0.1839	0.7605
Loa Loa (eye worm)	ACC-1 protein	0.0103	0.2406	0.5789
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0032	0.0599	0.1435
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Onchocerca volvulus		0.0032	0.0599	0.2375
Leishmania major	cysteine peptidase A (CPA)	0.0032	0.0599	0.373
Schistosoma mansoni	cpg binding protein	0.003	0.0539	0.0531
Onchocerca volvulus		0.008	0.1839	0.7605
Schistosoma mansoni	neurotransmitter gated ion channel	0.0055	0.1195	0.1187
Plasmodium vivax	serine-repeat antigen (SERA)	0.001	0.0036	0.0451
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Echinococcus granulosus	nephrin	0.0099	0.2327	0.2325
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.001	0.0036	0.0079
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0055	0.1195	0.1187
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Brugia malayi	cathepsin F-like cysteine proteinase	0.001	0.0036	0.0081
Loa Loa (eye worm)	ctsf protein	0.0032	0.0599	0.1435
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0103	0.2406	0.2404
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0103	0.2406	0.24
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0171	0.4155	0.415
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0171	0.4155	0.415
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0103	0.2406	0.5489
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Echinococcus granulosus	defective proboscis extension response	0.0085	0.196	0.1958
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.001	0.0036	0.0027
Echinococcus granulosus	irregular chiasm roughest protein	0.0099	0.2327	0.2325
Trypanosoma cruzi	isocitrate dehydrogenase [NADP], mitochondrial precursor, putative	0.0015	0.0176	0.0402
Loa Loa (eye worm)	hypothetical protein	0.0085	0.196	0.4714
Onchocerca volvulus		0.0055	0.1195	0.4891
Brugia malayi	hypothetical protein	0.0047	0.0992	0.2262
Echinococcus multilocularis	nephrin	0.0099	0.2327	0.2325
Plasmodium vivax	vivapain-2	0.0032	0.0599	1
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Brugia malayi	hypothetical protein	0.018	0.4385	1
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0103	0.2406	0.2404
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit type	0.0047	0.0992	0.0989
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0103	0.2406	0.2404
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Echinococcus multilocularis	cysteine protease	0.0032	0.0599	0.0596
Echinococcus multilocularis	cysteine protease	0.0032	0.0599	0.0596
Brugia malayi	Papain family cysteine protease containing protein	0.0019	0.0264	0.0602
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0103	0.2406	0.2404
Plasmodium vivax	serine-repeat antigen (SERA)	0.001	0.0036	0.0451
Trypanosoma cruzi	cysteine proteinase, putative	0.0019	0.0264	0.0615
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0599	0.1435
Loa Loa (eye worm)	hypothetical protein	0.001	0.0036	0.0079
Plasmodium vivax	vivapain-2	0.0032	0.0599	1
Entamoeba histolytica	cysteine proteinase, putative	0.0032	0.0599	0.4854
Echinococcus granulosus	cathepsin L cysteine protease	0.0019	0.0264	0.0261
Schistosoma mansoni	nAChR subunit	0.0103	0.2406	0.24
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Echinococcus multilocularis	cathepsin L	0.0019	0.0264	0.0261
Schistosoma mansoni	cathepsin F (C01 family)	0.0023	0.037	0.0362
Brugia malayi	hypothetical protein	0.0047	0.0992	0.2262
Echinococcus granulosus	cysteine protease	0.0019	0.0264	0.0261
Echinococcus granulosus	geminin	0.0165	0.4014	0.4013
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Onchocerca volvulus	Putative nachr subunit	0.0103	0.2406	1
Echinococcus granulosus	Immunoglobulin	0.0085	0.196	0.1958
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0032	0.0599	1
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.0023	0.037	0.0871
Echinococcus granulosus	cathepsin b	0.0171	0.4155	0.4153
Loa Loa (eye worm)	hypothetical protein	0.0009	0.0009	0.0015
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0103	0.2406	0.2404
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0032	0.0599	0.4419
Trypanosoma cruzi	cysteine peptidase, putative	0.0032	0.0599	0.1422
Schistosoma mansoni	neurotransmitter gated ion channel	0.0047	0.0992	0.0984
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0103	0.2406	0.2404
Toxoplasma gondii	cathepsin B	0.006	0.131	1
Onchocerca volvulus		0.0103	0.2406	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Toxoplasma gondii	isocitrate dehydrogenase	0.0015	0.0176	0.1098
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0103	0.2406	0.24
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0103	0.2406	0.5489
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Echinococcus multilocularis	cathepsin L cysteine protease	0.0032	0.0599	0.0596
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0103	0.2406	0.5789
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0103	0.2406	0.2404
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.001	0.0036	0.0079
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0103	0.2406	0.2404
Schistosoma mansoni	cpg binding protein	0.0028	0.0498	0.049
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.001	0.0036	0.0451
Echinococcus granulosus	cathepsin b	0.0171	0.4155	0.4153
Onchocerca volvulus		0.0032	0.0599	0.2375
Echinococcus multilocularis	nAChR subunit	0.0055	0.1195	0.1193
Onchocerca volvulus	Tyrosine kinase homolog	0.008	0.1839	0.7605
Loa Loa (eye worm)	hypothetical protein	0.001	0.0036	0.0079
Loa Loa (eye worm)	hypothetical protein	0.001	0.0036	0.0079
Echinococcus multilocularis	glycine receptor subunit beta	0.0103	0.2406	0.2404
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Onchocerca volvulus	Basement membrane proteoglycan homolog	0.008	0.1839	0.7605
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0019	0.0264	0.1791
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0176	0.0173
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0498	0.1193
Entamoeba histolytica	cysteine proteinase, putative	0.0019	0.0264	0.1968
Onchocerca volvulus		0.0103	0.2406	1
Brugia malayi	Neuronal acetylcholine receptor protein, alpha-2 chain precursor	0.0047	0.0992	0.2262
Echinococcus granulosus	cathepsin l1	0.0032	0.0599	0.0596
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Loa Loa (eye worm)	hypothetical protein	0.0047	0.0992	0.2382
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Entamoeba histolytica	cysteine proteinase, putative	0.0019	0.0264	0.1968
Loa Loa (eye worm)	hypothetical protein	0.0055	0.1195	0.2872
Echinococcus granulosus	cathepsin l1	0.0023	0.037	0.0368
Echinococcus multilocularis	glycine receptor subunit beta	0.0103	0.2406	0.2404
Trypanosoma cruzi	cysteine peptidase, putative	0.0032	0.0599	0.1422
Echinococcus granulosus	hemicentin 1	0.008	0.1839	0.1836
Giardia lamblia	Cathepsin B precursor	0.006	0.131	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0032	0.0599	0.373
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0085	0.196	0.4714
Echinococcus granulosus	glycine receptor subunit beta	0.0103	0.2406	0.2404
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0032	0.0599	0.4419
Entamoeba histolytica	cysteine proteinase 2	0.0019	0.0264	0.1968
Leishmania major	cathepsin L-like protease	0.0032	0.0599	0.373
Schistosoma mansoni	cathepsin F (C01 family)	0.0032	0.0599	0.059
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0055	0.1195	0.2726
Brugia malayi	hypothetical protein	0.0047	0.0992	0.2262
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0103	0.2406	0.5489
Echinococcus granulosus	gamma aminobutyric acid receptor subunit	0.0047	0.0992	0.0989
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0032	0.0599	1
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0103	0.2406	0.2404
Onchocerca volvulus	Cathepsin L homolog	0.0032	0.0599	0.2375
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0032	0.0599	0.1435
Echinococcus granulosus	contactin	0.008	0.1839	0.1836
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0103	0.2406	0.5489
Brugia malayi	Cathepsin L-like cysteine proteinase	0.0023	0.037	0.0845
Onchocerca volvulus		0.0103	0.2406	1
Entamoeba histolytica	cysteine protease, putative	0.0019	0.0264	0.1968
Schistosoma mansoni	acetylcholine receptor-related	0.0047	0.0992	0.0984
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0055	0.1195	0.2726
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0103	0.2406	0.2404
Loa Loa (eye worm)	hypothetical protein	0.0103	0.2406	0.5789

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	= 7.1 nM	Inhibition of human cathepsin L.	ChEMBL.	9784105
IC50 (binding)	= 530 nM	Inhibition of human cathepsin B	ChEMBL.	9784105
Ratio (binding)	= 74	Ratio of IC50 for Cathepsin B to that for Cathepsin L	ChEMBL.	9784105

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: 325021

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 236269