Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1912 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.005 | 0.0101 |
Loa Loa (eye worm) | phosphofructokinase | 0.0126 | 0.0768 | 0.4358 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0139 | 0.0857 | 0.5786 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.005 | 0.0135 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1871 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.005 | 0.005 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0019 | 0.0031 | 0.0001 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0034 | 0.0134 | 0.0626 |
Trichomonas vaginalis | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0125 | 0.0761 | 0.5112 |
Echinococcus multilocularis | bloom syndrome protein | 0.0025 | 0.007 | 0.0265 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0858 | 0.4873 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Echinococcus granulosus | single minded 2 | 0.0054 | 0.0273 | 0.1075 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0329 | 0.2159 | 0.2232 |
Trichomonas vaginalis | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.005 | 0.0242 |
Leishmania major | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Brugia malayi | reverse transcriptase | 0.0032 | 0.0119 | 0.0539 |
Echinococcus granulosus | KRAB A domain containing protein | 0.0032 | 0.0119 | 0.0459 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0213 | 0.1363 | 0.1336 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0115 | 0.0655 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0034 | 0.0134 | 0.0543 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Brugia malayi | RNase H family protein | 0.0297 | 0.194 | 1 |
Echinococcus granulosus | ribonuclease H1 | 0.0297 | 0.194 | 0.7724 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0126 | 0.0768 | 0.3047 |
Onchocerca volvulus | 0.0032 | 0.0119 | 0.0461 | |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0034 | 0.0134 | 0.0626 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0125 | 0.0761 | 0.5113 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.005 | 0.005 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0025 | 0.007 | 0.0286 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.005 | 0.0135 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0019 | 0.0031 | 0.008 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0297 | 0.194 | 1 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0271 | 0.1762 | 1 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0329 | 0.2159 | 0.2232 |
Brugia malayi | glutathione reductase | 0.0055 | 0.0278 | 0.1362 |
Loa Loa (eye worm) | thymidylate kinase | 0.0227 | 0.1459 | 0.8283 |
Schistosoma mansoni | hypothetical protein | 0.038 | 0.251 | 0.2487 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Schistosoma mansoni | hypothetical protein | 0.038 | 0.251 | 0.2487 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0019 | 0.0031 | 0.0088 |
Giardia lamblia | Thymidine kinase | 0.058 | 0.3885 | 1 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0126 | 0.0768 | 0.3047 |
Schistosoma mansoni | phosphoglucomutase | 0.0297 | 0.194 | 0.1915 |
Trypanosoma brucei | thymidine kinase | 0.058 | 0.3885 | 0.4041 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0025 | 0.007 | 0.0103 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.0739 |
Trypanosoma cruzi | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0267 | 0.1736 | 0.1711 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0055 | 0.0278 | 0.1727 |
Giardia lamblia | CDC8 | 0.0227 | 0.1459 | 0.3706 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0115 | 0.0519 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Mycobacterium ulcerans | thymidylate kinase | 0.0227 | 0.1459 | 1 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0139 | 0.0857 | 0.5785 |
Echinococcus granulosus | geminin | 0.038 | 0.251 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.005 | 0.0135 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0032 | 0.0119 | 0.0229 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0032 | 0.0119 | 0.0461 |
Trypanosoma brucei | Endonuclease-reverse transcriptase/Reverse transcriptase (RNA-dependent DNA polymerase), putative | 0.0032 | 0.0119 | 0.0092 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0019 | 0.0031 | 0.0001 |
Schistosoma mansoni | single-minded | 0.0073 | 0.0404 | 0.0375 |
Schistosoma mansoni | phosphoglucomutase | 0.0297 | 0.194 | 0.1915 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0126 | 0.0768 | 0.5159 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0159 | 0.099 | 0.3932 |
Mycobacterium tuberculosis | Thymidylate kinase Tmk (dTMP kinase) (thymidylic acid kinase) (TMPK) | 0.0227 | 0.1459 | 1 |
Echinococcus granulosus | bloom syndrome protein | 0.0025 | 0.007 | 0.0265 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0019 | 0.0031 | 0.0001 |
Entamoeba histolytica | Thymidylate kinase, putative | 0.0227 | 0.1459 | 0.3674 |
Schistosoma mansoni | protein kinase | 0.0032 | 0.0119 | 0.0088 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Brugia malayi | follicle stimulating hormone receptor | 0.0271 | 0.1762 | 0.9074 |
Loa Loa (eye worm) | RecQ helicase | 0.0025 | 0.007 | 0.04 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0034 | 0.0134 | 0.022 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0125 | 0.0761 | 0.5113 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.005 | 0.005 |
Brugia malayi | phosphofructokinase | 0.0126 | 0.0768 | 0.3909 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.005 | 0.0184 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Plasmodium vivax | thymidylate kinase, putative | 0.0227 | 0.1459 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0115 | 0.0444 |
Brugia malayi | Kringle domain containing protein | 0.0019 | 0.0031 | 0.0081 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0032 | 0.0119 | 0.0459 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0019 | 0.0031 | 0.0088 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0015 | 0.0087 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0032 | 0.0119 | 0.0229 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0034 | 0.0134 | 0.0725 |
Brugia malayi | RNase H family protein | 0.0297 | 0.194 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0055 | 0.0278 | 0.0259 |
Trichomonas vaginalis | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0227 | 0.1459 | 0.3706 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0826 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0126 | 0.0768 | 0.1912 |
Brugia malayi | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.3909 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0031 | 0.0001 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0019 | 0.0031 | 0.0108 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0126 | 0.0768 | 0.516 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0089 | 0.0512 | 0.1248 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.4358 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0176 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0329 | 0.2159 | 0.2232 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0019 | 0.0031 | 0.0001 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.005 | 0.0189 |
Trypanosoma brucei | unspecified product | 0.0329 | 0.2159 | 0.2232 |
Schistosoma mansoni | scy1(yeast) protein kinase-like | 0.0032 | 0.0119 | 0.0088 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.002 | 0.0035 | 0.0004 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.4358 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0036 | 0.0204 |
Brugia malayi | aryl hydrocarbon receptor AHR-1 | 0.0139 | 0.0854 | 0.4358 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0019 | 0.0031 | 0.0109 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0139 | 0.0857 | 0.5786 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1871 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0031 | 0.0001 |
Plasmodium falciparum | thymidylate kinase | 0.0227 | 0.1459 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0019 | 0.0031 | 0.0081 |
Echinococcus granulosus | thymidylate kinase | 0.0227 | 0.1459 | 0.5806 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1912 |
Mycobacterium tuberculosis | Probable reductase | 0.0125 | 0.0761 | 0.5113 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0032 | 0.0119 | 0.0459 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0119 | 0.0088 |
Mycobacterium leprae | probable thymidylate kinase Tmk (dTMP KINASE) (THYMIDYLIC ACID KINASE) (TMPK) | 0.0227 | 0.1459 | 1 |
Leishmania major | trypanothione reductase | 0.0055 | 0.0278 | 0.064 |
Trypanosoma brucei | SLACS reverse transcriptase, putative | 0.0032 | 0.0119 | 0.0092 |
Trypanosoma brucei | RNA helicase, putative | 0.1407 | 0.9568 | 1 |
Toxoplasma gondii | kringle domain-containing protein | 0.0019 | 0.0031 | 0.0089 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0032 | 0.0119 | 0.0459 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0034 | 0.0134 | 0.0725 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0297 | 0.194 | 0.4953 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Loa Loa (eye worm) | glutathione reductase | 0.0055 | 0.0278 | 0.1575 |
Echinococcus multilocularis | ribonuclease H1 | 0.0297 | 0.194 | 0.7724 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0055 | 0.0278 | 0.1092 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.005 | 0.0285 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0034 | 0.0134 | 0.0725 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0119 | 0.0539 |
Trichomonas vaginalis | reverse transcriptases, putative | 0.0032 | 0.0119 | 0.0229 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0019 | 0.0031 | 0.0107 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.0985 | 0.5592 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0025 | 0.007 | 0.0103 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0031 | 0.0082 |
Echinococcus multilocularis | thymidylate kinase | 0.0227 | 0.1459 | 0.5806 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0032 | 0.0119 | 0.0229 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.005 | 0.0019 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0019 | 0.0031 | 0.0001 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.516 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.002 | 0.0035 | 0.0201 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0119 | 0.0539 |
Toxoplasma gondii | thioredoxin reductase | 0.0055 | 0.0278 | 0.1369 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0125 | 0.0761 | 0.5113 |
Trypanosoma cruzi | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Entamoeba histolytica | thymidine kinase, putative | 0.058 | 0.3885 | 1 |
Schistosoma mansoni | lamin | 0.0031 | 0.0115 | 0.0085 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Onchocerca volvulus | 0.0032 | 0.0119 | 0.0461 | |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0032 | 0.0119 | 0.0459 |
Leishmania major | protein kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0032 | 0.0119 | 0.0459 |
Giardia lamblia | Reverse transcriptase/endonuclease | 0.0032 | 0.0119 | 0.0229 |
Brugia malayi | RNase H family protein | 0.0297 | 0.194 | 1 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0019 | 0.0031 | 0.0001 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0227 | 0.1459 | 0.3706 |
Trypanosoma cruzi | UMP-CMP kinase, mitochondrial, putative | 0.0089 | 0.0512 | 0.1248 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.002 | 0.0035 | 0.0126 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0826 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.005 | 0.0019 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0032 | 0.0119 | 0.0459 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0055 | 0.0278 | 0.1817 |
Brugia malayi | Thioredoxin reductase | 0.0055 | 0.0278 | 0.1362 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0177 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0034 | 0.0134 | 0.0269 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.005 | 0.0184 |
Echinococcus granulosus | lamin | 0.0031 | 0.0115 | 0.0444 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0055 | 0.0278 | 0.064 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0055 | 0.0278 | 0.1575 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0034 | 0.0134 | 0.0626 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0297 | 0.194 | 1 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0227 | 0.1459 | 0.1498 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0019 | 0.0031 | 0.0001 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0022 | 0.005 | 0.0132 |
Leishmania major | thymidylate kinase-like protein | 0.0227 | 0.1459 | 0.3706 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Leishmania major | protein kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Trypanosoma brucei | ribonuclease H1 | 0.0297 | 0.194 | 0.2002 |
Schistosoma mansoni | hypothetical protein | 0.0227 | 0.1459 | 0.1433 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0126 | 0.0768 | 0.0773 |
Plasmodium vivax | glutathione reductase, putative | 0.0055 | 0.0278 | 0.1817 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0115 | 0.0519 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0115 | 0.0085 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.005 | 0.0101 |
Toxoplasma gondii | thymidylate kinase | 0.0227 | 0.1459 | 0.7504 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Brugia malayi | reverse transcriptase | 0.0032 | 0.0119 | 0.0539 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0139 | 0.0857 | 0.5786 |
Trichomonas vaginalis | thymidylate kinase, putative | 0.0227 | 0.1459 | 0.3706 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0329 | 0.2159 | 0.2232 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Onchocerca volvulus | 0.0158 | 0.0985 | 0.4998 | |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0115 | 0.0444 |
Trichomonas vaginalis | reverse transcriptases, putative | 0.0032 | 0.0119 | 0.0229 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0297 | 0.194 | 0.4953 |
Schistosoma mansoni | phosphoglucomutase | 0.0297 | 0.194 | 0.1915 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0019 | 0.0031 | 0.0108 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1912 |
Leishmania major | hypothetical protein, conserved | 0.0089 | 0.0512 | 0.1248 |
Echinococcus granulosus | RNA directed DNA polymerase reverse transcriptase | 0.0032 | 0.0119 | 0.0459 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0019 | 0.0031 | 0.0108 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0019 | 0.0031 | 0.0176 |
Brugia malayi | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.3909 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0119 | 0.0088 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.005 | 0.005 |
Wolbachia endosymbiont of Brugia malayi | thymidylate kinase | 0.0227 | 0.1459 | 0.7482 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0019 | 0.0031 | 0.0001 |
Trichomonas vaginalis | NeSL-1_NeSL reverse transcriptases, putative | 0.0032 | 0.0119 | 0.0229 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0019 | 0.0031 | 0.0107 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Trypanosoma brucei | SLACS retrotransposable element (part), putative | 0.0032 | 0.0119 | 0.0092 |
Giardia lamblia | Reverse transcriptase/endonuclease, putative | 0.0032 | 0.0119 | 0.0229 |
Onchocerca volvulus | 0.0031 | 0.0115 | 0.0442 | |
Trichomonas vaginalis | reverse transcriptase [C. elegans], putative | 0.0032 | 0.0119 | 0.0229 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0055 | 0.0278 | 0.1092 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0125 | 0.0761 | 0.5113 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0115 | 0.0444 |
Mycobacterium tuberculosis | Possible maturase | 0.0032 | 0.0119 | 0.0617 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0126 | 0.0768 | 0.0739 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0115 | 0.0655 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.005 | 0.005 |
Brugia malayi | PAS domain containing protein | 0.0073 | 0.0404 | 0.2022 |
Chlamydia trachomatis | thymidylate kinase | 0.0227 | 0.1459 | 1 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0119 | 0.0539 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0159 | 0.099 | 0.3932 |
Schistosoma mansoni | hypothetical protein | 0.1407 | 0.9568 | 0.9566 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0854 | 0.4848 |
Plasmodium falciparum | glutathione reductase | 0.0055 | 0.0278 | 0.1727 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0297 | 0.194 | 1 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Brugia malayi | bHLH-PAS transcription factor | 0.0054 | 0.0273 | 0.134 |
Schistosoma mansoni | thymidylate kinase | 0.0227 | 0.1459 | 0.1433 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0111 | 0.0632 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0297 | 0.194 | 0.4953 |
Mycobacterium ulcerans | putative regulatory protein | 0.0054 | 0.0273 | 0.1698 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0019 | 0.0031 | 0.0001 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.002 | 0.0035 | 0.0126 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1871 |
Schistosoma mansoni | thymidylate kinase | 0.0227 | 0.1459 | 0.1433 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0019 | 0.0031 | 0.0002 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0032 | 0.0119 | 0.0229 |
Brugia malayi | Zinc knuckle family protein | 0.0032 | 0.0119 | 0.0539 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0019 | 0.0031 | 0.0108 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0115 | 0.0655 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0119 | 0.0539 |
Trypanosoma brucei | thymidylate kinase, putative | 0.0227 | 0.1459 | 0.1498 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0125 | 0.0761 | 0.5113 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0126 | 0.0768 | 0.1912 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.005 | 0.002 |
Onchocerca volvulus | Putative thymidylate kinase | 0.0227 | 0.1459 | 0.7481 |
Brugia malayi | reverse transcriptase | 0.0032 | 0.0119 | 0.0539 |
Leishmania major | ribonuclease H1, putative | 0.0297 | 0.194 | 0.4953 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0034 | 0.0134 | 0.0725 |
Onchocerca volvulus | 0.0031 | 0.0115 | 0.0442 | |
Schistosoma mansoni | lamin | 0.0031 | 0.0115 | 0.0085 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0115 | 0.0444 |
Toxoplasma gondii | ribonuclease HI protein | 0.0297 | 0.194 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0004 | 0.0022 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0034 | 0.0134 | 0.0269 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0019 | 0.0031 | 0.0001 |
Brugia malayi | thymidylate kinase | 0.0227 | 0.1459 | 0.7502 |
Trypanosoma cruzi | thymidylate kinase, putative | 0.0227 | 0.1459 | 0.3706 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0126 | 0.0768 | 0.386 |
Echinococcus multilocularis | RNA directed DNA polymerase (reverse transcriptase) | 0.0032 | 0.0119 | 0.0459 |
Giardia lamblia | Ribonuclease H | 0.0297 | 0.194 | 0.4953 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0115 | 0.0444 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0019 | 0.0031 | 0.0001 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0032 | 0.0119 | 0.0088 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.005 | 0.0181 |
Brugia malayi | Zinc knuckle family protein | 0.0032 | 0.0119 | 0.0539 |
Echinococcus multilocularis | geminin | 0.038 | 0.251 | 1 |
Treponema pallidum | thymidylate kinase (tmk) | 0.0227 | 0.1459 | 0.7482 |
Plasmodium falciparum | thioredoxin reductase | 0.0055 | 0.0278 | 0.1727 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0054 | 0.0273 | 0.1075 |
Brugia malayi | Pao retrotransposon peptidase family protein | 0.0032 | 0.0119 | 0.0539 |
Onchocerca volvulus | 0.0055 | 0.0278 | 0.1292 | |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0126 | 0.0768 | 0.1912 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (binding) | = 4.553 | Affinity of the compound was determined on cytosolic Aromatic hydrocarbon receptor (Ah) | ChEMBL. | 9435905 |
Log EC50 (binding) | = 4.553 | Affinity of the compound was determined on cytosolic Aromatic hydrocarbon receptor (Ah) | ChEMBL. | 9435905 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.