Detailed information for compound 23633

Basic information

Technical information
  • TDR Targets ID: 23633
  • Name: 2-(6-chloronaphthalen-2-yl)-N-[2-fluoro-4-(2- sulfamoylphenyl)phenyl]-5-methylpyrazole-3-ca rboxamide
  • MW: 534.989 | Formula: C27H20ClFN4O3S
  • H donors: 2 H acceptors: 4 LogP: 5.63 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: Clc1ccc2c(c1)ccc(c2)n1nc(cc1C(=O)Nc1ccc(cc1F)c1ccccc1S(=O)(=O)N)C
  • InChi: 1S/C27H20ClFN4O3S/c1-16-12-25(33(32-16)21-10-7-17-13-20(28)9-6-18(17)14-21)27(34)31-24-11-8-19(15-23(24)29)22-4-2-3-5-26(22)37(30,35)36/h2-15H,1H3,(H,31,34)(H2,30,35,36)
  • InChiKey: YHBAUSHIRREVLG-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 2-(6-chloro-2-naphthyl)-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-methyl-pyrazole-3-carboxamide
  • 2-(6-chloro-2-naphthyl)-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-methyl-3-pyrazolecarboxamide
  • 2-(6-chloronaphthalen-2-yl)-N-[2-fluoro-4-(2-sulfamoylphenyl)phenyl]-5-methyl-pyrazole-3-carboxamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens coagulation factor X Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi STAT protein, DNA binding domain containing protein 0.0133 0.0504 0.0833
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0496 0.1982 1
Loa Loa (eye worm) hypothetical protein 0.0496 0.1982 0.483
Echinococcus granulosus laminin 0.0016 0.0028 0.0035
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Schistosoma mansoni smad 0.0016 0.0027 0.0048
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0079
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0562 0.2251 0.2831
Brugia malayi Pyruvate kinase, muscle isozyme 0.0067 0.0234 0.0387
Brugia malayi Cytochrome P450 family protein 0.0014 0.0021 0.0034
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0496 0.1982 1
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0021 0.0051
Schistosoma mansoni lipoxygenase 0.0107 0.0397 0.071
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0236 0.0575
Trypanosoma brucei ribokinase, putative 0.009 0.0329 0.102
Schistosoma mansoni regulator of G protein signaling 0.004 0.0126 0.0225
Schistosoma mansoni adenylate cyclase 0.0014 0.0018 0.0033
Trypanosoma cruzi ribokinase, putative 0.009 0.0329 0.102
Brugia malayi CXXC zinc finger family protein 0.003 0.0083 0.0138
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Brugia malayi adenylate cyclase, type IX 0.0014 0.0018 0.003
Loa Loa (eye worm) neuropeptide F receptor 0.0562 0.2251 0.5484
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0236 0.0422
Entamoeba histolytica hypothetical protein 0.0111 0.0415 0.206
Onchocerca volvulus 0.0562 0.2251 0.6211
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Toxoplasma gondii kinase, pfkB family protein 0.009 0.0329 0.102
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0031 0.0079
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0014 0.0018 0.0047
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0126 0.0126
Schistosoma mansoni rotamase 0.0035 0.0103 0.0184
Echinococcus multilocularis GPCR, family 2 0.0046 0.015 0.015
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.004 0.0126 0.0592
Echinococcus granulosus histone lysine methyltransferase setb 0.0061 0.0208 0.0262
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0008 0.0013
Brugia malayi PXA domain containing protein 0.004 0.0126 0.0208
Brugia malayi GnHR receptor homolog 0.0562 0.2251 0.372
Echinococcus granulosus orexin receptor type 2 0.0562 0.2251 0.2831
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.0417 0.1658 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0146 0.0557 0.1356
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0036 0.0098
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.0129 0.0488 0.0806
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.0273 0.1073 0.3359
Echinococcus granulosus somatostatin receptor 0.0562 0.2251 0.2831
Trichomonas vaginalis adenylate cyclase, putative 0.0027 0.0072 0.0318
Loa Loa (eye worm) hypothetical protein 0.0078 0.0278 0.0677
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0027 0.0034
Brugia malayi neuropeptide F receptor 0.0562 0.2251 0.372
Echinococcus multilocularis Tolloid protein 1 0.0016 0.0028 0.0028
Trypanosoma brucei purine nucleoside transporter 0.0086 0.0313 0.0969
Brugia malayi hypothetical protein 0.0016 0.0028 0.0046
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0562 0.2251 0.2831
Onchocerca volvulus 0.004 0.0126 0.0347
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0496 0.1982 1
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0273 0.1073 0.3359
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0208 0.0372
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0278 0.1582
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0288 0.1133 0.2761
Loa Loa (eye worm) hypothetical protein 0.0046 0.015 0.0366
Trypanosoma brucei procyclic-enriched flagellar receptor adenylate cyclase 3 0.0014 0.0018 0.0042
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis solute carrier family 5 0.0037 0.0113 0.0113
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Schistosoma mansoni histamine h1 receptor 0.0562 0.2251 0.4024
Echinococcus multilocularis equilibrative nucleoside transporter protein 0.0496 0.1982 0.1982
Schistosoma mansoni axis inhibition protein axin 0.004 0.0126 0.0225
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0132 0.0235
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.0113 0.0142
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0027 0.0072 0.0318
Onchocerca volvulus 0.0562 0.2251 0.6211
Echinococcus granulosus tumor protein p63 0.0701 0.2814 0.3539
Echinococcus multilocularis neuropeptide receptor A26 0.104 0.4194 0.4194
Brugia malayi isocitrate dehydrogenase 0.0016 0.0026 0.0043
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis hypothetical protein 0.0014 0.0018 0.0047
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0014 0.0021 0.0016
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0089 0.0323 0.155
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei adenosine transporter 2, putative 0.0086 0.0313 0.0969
Loa Loa (eye worm) hypothetical protein 0.0103 0.0379 0.0925
Loa Loa (eye worm) pyruvate kinase 0.0014 0.0019 0.0047
Schistosoma mansoni protein kinase 0.0014 0.0018 0.0033
Toxoplasma gondii cytochrome p450 superfamily protein 0.0014 0.0021 0.005
Schistosoma mansoni lamin 0.0054 0.0182 0.0326
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0218 0.0672
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0068 0.024 0.0397
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0026 0.0067
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0126 0.0158
Onchocerca volvulus 0.0061 0.0208 0.0575
Trichomonas vaginalis Phosphoglycerol transferase I, putative 0.0018 0.0034 0.0125
Onchocerca volvulus 0.0037 0.0113 0.0312
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0027 0.0027
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0056
Loa Loa (eye worm) hypothetical protein 0.009 0.0329 0.0802
Schistosoma mansoni hypothetical protein 0.01 0.0369 0.0659
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0015 0.0033
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0033
Echinococcus multilocularis transfer RNA-Lys 0.0037 0.0114 0.0114
Schistosoma mansoni amine GPCR 0.0562 0.2251 0.4024
Onchocerca volvulus 0.0014 0.0018 0.005
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0015 0.0033
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0306
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trypanosoma brucei nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Brugia malayi cytochrome P450 0.0014 0.0021 0.0034
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0182 0.0444
Toxoplasma gondii thioredoxin reductase 0.0049 0.0162 0.0493
Echinococcus granulosus neuropeptide receptor 0.0562 0.2251 0.2831
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0031 0.0052
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0307
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0061 0.0208 0.0208
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0034 0.01 0.0298
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0014 0.0021 0.002
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0234 0.0722
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.024 0.0741
Mycobacterium ulcerans pyruvate kinase 0.0067 0.0234 0.1317
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0014 0.0021 0.0016
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0014 0.0018 0.0047
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0562 0.2251 0.4024
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0126 0.0158
Brugia malayi sulfakinin receptor protein 0.0562 0.2251 0.372
Echinococcus multilocularis sex peptide receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Brugia malayi Serotonin receptor 0.0562 0.2251 0.372
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis phosphofructokinase, putative 0.0328 0.1297 0.6527
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0126 0.0158
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0417 0.1658 0.2965
Trichomonas vaginalis phosphofructokinase, putative 0.0089 0.0323 0.159
Trichomonas vaginalis phosphofructokinase, putative 0.0089 0.0323 0.159
Schistosoma mansoni hypothetical protein 0.0562 0.2251 0.4024
Schistosoma mansoni neuropeptide f receptor 76f 0.0562 0.2251 0.4024
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0031 0.0083
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0014 0.0021 0.002
Echinococcus granulosus equilibrative nucleoside transporter 3 0.0496 0.1982 0.2493
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0562 0.2251 0.5484
Brugia malayi Tachykinin-like peptides receptor 99D 0.0562 0.2251 0.372
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0031
Mycobacterium ulcerans fructokinase, PfkB 0.009 0.0329 0.1895
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0562 0.2251 0.2251
Schistosoma mansoni hypothetical protein 0.004 0.0126 0.0225
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0033
Schistosoma mansoni amine GPCR 0.0562 0.2251 0.4024
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0018 0.0034 0.0093
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0086 0.0313 0.154
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0126 0.0655
Brugia malayi Doublecortin family protein 0.004 0.0126 0.0208
Echinococcus granulosus cpg binding protein 0.0032 0.009 0.0114
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0014 0.0021 0.0016
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.0417 0.1658 1
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Schistosoma mansoni intermediate filament proteins 0.0054 0.0182 0.0326
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus multilocularis adenylate cyclase 9 0.0014 0.0018 0.0018
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0236 0.0422
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0033
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0021 0.0051
Echinococcus granulosus adenylate cyclase type IX 0.0014 0.0018 0.0023
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.0417 0.1658 0.5203
Brugia malayi RE15519p 0.0562 0.2251 0.372
Echinococcus multilocularis pyruvate kinase 0.0067 0.0234 0.0234
Schistosoma mansoni hypothetical protein 0.0562 0.2251 0.4024
Echinococcus granulosus g-protein coupled receptor 0.0562 0.2251 0.2831
Brugia malayi 6-phosphofructokinase 0.0328 0.1297 0.2143
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.0598 0.1069
Echinococcus multilocularis mixed lineage leukemia protein mll 0.001 0.0001 0.0001
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0014 0.0021 0.002
Toxoplasma gondii endonuclease IV APN 0.0078 0.0278 0.0858
Entamoeba histolytica nucleoside transporter, putative 0.0086 0.0313 0.154
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0562 0.2251 0.5484
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0307
Toxoplasma gondii kinase, pfkB family protein 0.0791 0.3183 1
Treponema pallidum NADH oxidase 0.0017 0.0031 0.0079
Schistosoma mansoni opsin-like receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) latrophilin receptor protein 2 0.0046 0.015 0.0366
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Loa Loa (eye worm) doublecortin family protein 0.004 0.0126 0.0306
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Schistosoma mansoni hypothetical protein 0.0011 0.0008 0.0014
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0086 0.0313 0.0969
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0026 0.0067
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0496 0.1982 0.5469
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0061 0.0208 0.064
Echinococcus granulosus pyruvate kinase 0.0034 0.0102 0.0128
Trypanosoma brucei procyclic-enriched flagellar receptor adenylate cyclase 4 0.0014 0.0018 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Brugia malayi putative neuropeptide receptor 0.0562 0.2251 0.372
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis cpg binding protein 0.0032 0.009 0.009
Loa Loa (eye worm) pyruvate kinase-PB 0.0047 0.0152 0.037
Echinococcus granulosus lamin dm0 0.0054 0.0182 0.0229
Loa Loa (eye worm) PXA domain-containing protein 0.004 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0328 0.1297 1
Leishmania major ATP-dependent phosphofructokinase 0.0328 0.1297 0.4065
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus granulosus Ankyrin 0.0044 0.014 0.0176
Echinococcus multilocularis microtubule associated protein 2 0.1384 0.5593 0.5593
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0112 0.0418 0.3123
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0089 0.0323 0.187
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0018 0.0047
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0031 0.0079
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0156 0.0598 0.1866
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0024 0.006
Leishmania major tagatose-6-phosphate kinase-like protein 0.009 0.0329 0.102
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0026 0.0048
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0072 0.0318
Brugia malayi Nucleoside transporter family protein 0.0496 0.1982 0.3276
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Schistosoma mansoni neuropeptide receptor 0.0562 0.2251 0.4024
Schistosoma mansoni adenoreceptor 0.0562 0.2251 0.4024
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0026 0.0026
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0086 0.0313 0.0969
Brugia malayi pyruvate kinase, muscle isozyme 0.0014 0.0019 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0126 0.0592
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0014 0.0021 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0562 0.2251 0.2251
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0014 0.0021 0.002
Schistosoma mansoni opsin-like receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) hypothetical protein 0.0053 0.0178 0.0434
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni ap endonuclease 0.0018 0.0036 0.0065
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.0417 0.1658 1
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.016
Entamoeba histolytica phosphofructokinase, putative 0.0328 0.1297 0.6527
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0028 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0273 0.1073 0.2616
Echinococcus granulosus neuropeptide receptor 0.0562 0.2251 0.2831
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Mycobacterium tuberculosis Ribokinase RbsK 0.009 0.0329 0.2431
Echinococcus multilocularis G protein coupled receptor 139 0.0562 0.2251 0.2251
Schistosoma mansoni regulator of G protein signaling 0.004 0.0126 0.0225
Echinococcus granulosus neuropeptides capa receptor 0.0562 0.2251 0.2831
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0042 0.0132 0.0321
Plasmodium falciparum thioredoxin reductase 0.0049 0.0162 0.0875
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Brugia malayi regulator of G-protein signaling rgs-7 0.004 0.0126 0.0208
Onchocerca volvulus 0.0014 0.0018 0.005
Echinococcus multilocularis fmrfamide receptor 0.0562 0.2251 0.2251
Schistosoma mansoni protein kinase 0.0088 0.0319 0.057
Loa Loa (eye worm) transcription factor SMAD2 0.0234 0.0916 0.2232
Loa Loa (eye worm) hypothetical protein 0.0086 0.0313 0.0762
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0083 0.0203
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis adenylate cyclase 0.0014 0.0018 0.0018
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0036 0.0045
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.0013
Echinococcus granulosus tar DNA binding protein 0.0067 0.0236 0.0297
Schistosoma mansoni equilibrative nucleoside transporter 0.0086 0.0313 0.0559
Onchocerca volvulus 0.0562 0.2251 0.6211
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0126 0.0158
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0034 0.01 0.046
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0218 0.1566
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0026
Entamoeba histolytica hypothetical protein 0.0111 0.0415 0.206
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0086 0.0313 0.0969
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0124 0.0468 0.3521
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus multilocularis pyruvate kinase 0.0067 0.0234 0.0234
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0562 0.2251 0.4024
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0049 0.0162 0.1122
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0089 0.0323 0.159
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni receptor-type adenylate cyclase 0.0014 0.0018 0.0033
Schistosoma mansoni biogenic amine receptor 0.0562 0.2251 0.4024
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.01 0.0298
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus multilocularis neuropeptide FF receptor 2 0.0562 0.2251 0.2251
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1018 0.4104 1
Trypanosoma brucei procyclic-enriched flagellar receptor adenylate cyclase 5 0.0014 0.0018 0.0042
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0417 0.1658 0.1658
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0031 0.0083
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0031 0.0113
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0036 0.0091
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0417 0.1658 0.5203
Trypanosoma brucei adenosine transporter 2, putative 0.0086 0.0313 0.0969
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0234 0.0571
Entamoeba histolytica ribokinase, putative 0.009 0.0329 0.1622
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0031 0.0079
Brugia malayi latrophilin 2 splice variant baaae 0.01 0.0369 0.0609
Onchocerca volvulus 0.0562 0.2251 0.6211
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Onchocerca volvulus 0.0562 0.2251 0.6211
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0496 0.1982 1
Schistosoma mansoni hypothetical protein 0.0046 0.015 0.0268
Echinococcus granulosus adenylate cyclase 9 0.0014 0.0018 0.0023
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0417 0.1658 0.2965
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0036 0.0188
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0156 0.0598 0.1866
Echinococcus multilocularis musashi 0.0054 0.0182 0.0182
Leishmania major hypothetical protein, conserved 0.0025 0.0064 0.0187
Onchocerca volvulus Adenylate cyclase type 2 homolog 0.0325 0.1283 0.3541
Echinococcus multilocularis G-protein coupled receptor, putative 0.0562 0.2251 0.2251
Brugia malayi hypothetical protein 0.025 0.0978 0.1616
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Echinococcus multilocularis beta adrenergic receptor kinase 0.0042 0.0132 0.0132
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0014 0.0018 0.003
Brugia malayi Thioredoxin reductase 0.0049 0.0162 0.0267
Onchocerca volvulus 0.0562 0.2251 0.6211
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0044 0.014 0.025
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Echinococcus granulosus adenylate cyclase 9 0.0325 0.1283 0.1614
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Schistosoma mansoni amine GPCR 0.0562 0.2251 0.4024
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0009 0.0009
Schistosoma mansoni smad1 5 8 and 0.0016 0.0027 0.0048
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0218 0.1221
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.0496 0.1982 0.1982
Trichomonas vaginalis retinal guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0068 0.024 0.024
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.5203
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0218 0.0218
Echinococcus multilocularis g protein coupled receptor 0.0562 0.2251 0.2251
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0078 0.0278 0.203
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0046 0.015 0.015
Echinococcus granulosus mixed lineage leukemia protein mll 0.001 0.0001 0.0001
Leishmania major nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0014 0.0021 0.002
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.004 0.0126 0.0225
Leishmania major protein kinase, putative 0.0015 0.0021 0.0051
Trichomonas vaginalis phosphofructokinase, putative 0.0089 0.0323 0.159
Loa Loa (eye worm) pax transcription factor protein 2 0.024 0.0938 0.2285
Loa Loa (eye worm) 6-phosphofructokinase 0.0328 0.1297 0.316
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.002 0.0045 0.0124
Trypanosoma cruzi nucleobase transporter, putative 0.0086 0.0313 0.0969
Echinococcus granulosus smad 0.0016 0.0027 0.0034
Toxoplasma gondii adenylate and guanylate cyclase catalytic domain-containing protein 0.0014 0.0018 0.0042
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0234 0.0646
Echinococcus granulosus ribokinase 0.009 0.0329 0.0414
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0031 0.0083
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0026 0.0067
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0026 0.0043
Schistosoma mansoni z-protein (S1r protein) 0.004 0.0126 0.0225
Trypanosoma brucei unspecified product 0.0086 0.0313 0.0969
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0031 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0114 0.0584
Plasmodium vivax SET domain protein, putative 0.0061 0.0208 0.1159
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0112 0.0418 0.3123
Loa Loa (eye worm) RGS-3 protein 0.004 0.0126 0.0307
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Brugia malayi regulator of G-protein signaling egl-10 0.004 0.0126 0.0208
Brugia malayi Uncoordinated protein 44 0.0043 0.0139 0.0229
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0068 0.024 0.1173
Loa Loa (eye worm) hypothetical protein 0.0043 0.0139 0.0338
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0562 0.2251 0.2251
Brugia malayi RNA binding protein 0.0067 0.0236 0.039
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni hypothetical protein 0.0046 0.015 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Onchocerca volvulus Neuropeptide F receptor homolog 0.0562 0.2251 0.6211
Loa Loa (eye worm) hypothetical protein 0.0325 0.1283 0.3127
Echinococcus multilocularis expressed protein 0.0035 0.0103 0.0103
Echinococcus granulosus expressed protein 0.0035 0.0103 0.013
Leishmania major adenosine kinase-like protein 0.009 0.0329 0.102
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Schistosoma mansoni cpg binding protein 0.0032 0.009 0.0161
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis adenylate cyclase type vIII, putative 0.0014 0.0018 0.0047
Trypanosoma cruzi nucleoside transporter-like, putative 0.0086 0.0313 0.0969
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0035 0.0103 0.017
Brugia malayi Dopamine receptor protein 2 0.0562 0.2251 0.372
Leishmania major putative PfkB family sugar kinase 0.009 0.0329 0.102
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0068 0.024 0.043
Mycobacterium leprae Probable adenosine kinase adk 0.009 0.0329 0.2448
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0031 0.0079
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0014 0.0018 0.003
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0046 0.015 0.0248
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0562 0.2251 0.2831
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Loa Loa (eye worm) hypothetical protein 0.0169 0.0651 0.1587
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Mycobacterium tuberculosis Possible arylsulfatase AtsD (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0018 0.0034 0.012
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.004 0.0126 0.0158
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) thioredoxin reductase 0.0049 0.0162 0.0394
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.008 0.0195
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus granulosus RUN 0.004 0.0126 0.0158
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0562 0.2251 0.6211
Schistosoma mansoni serine/threonine RGC 0.0014 0.0018 0.0033
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0014 0.0021 0.005
Onchocerca volvulus 0.0562 0.2251 0.6211
Schistosoma mansoni Smad4 0.0016 0.0027 0.0048
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0058 0.0241
Echinococcus granulosus neuropeptide Y receptor 0.0562 0.2251 0.2831
Toxoplasma gondii exonuclease III APE 0.0018 0.0036 0.0098
Echinococcus multilocularis pseudouridine metabolizing bifunctional protein 0.009 0.0329 0.0329
Echinococcus multilocularis smad 0.0016 0.0027 0.0027
Loa Loa (eye worm) adenylyl cyclase 3 0.0325 0.1283 0.3127
Echinococcus multilocularis netrin receptor unc 5 0.0043 0.0139 0.0139
Schistosoma mansoni rab6-interacting 0.004 0.0126 0.0225
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0089 0.0323 0.1856
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Onchocerca volvulus Equilibrative nucleoside transporter, putative homolog 0.0496 0.1982 0.5469
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0273 0.1073 0.135
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0089 0.0323 0.159
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0066 0.016
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Plasmodium falciparum pyruvate kinase 0.0067 0.0234 0.1317
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0021 0.005
Schistosoma mansoni hypothetical protein 0.0516 0.2063 0.3688
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0562 0.2251 0.2251
Mycobacterium ulcerans endonuclease IV 0.0078 0.0278 0.1582
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0562 0.2251 0.2251
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0046 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.002 0.0045 0.011
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0018 0.0047
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0036 0.0098
Brugia malayi hypothetical protein 0.004 0.0126 0.0208
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Schistosoma mansoni hypothetical protein 0.0046 0.015 0.0268
Schistosoma mansoni hypothetical protein 0.0516 0.2063 0.3688
Mycobacterium ulcerans hydrolase 0.0018 0.0034 0.0094
Brugia malayi Death domain containing protein 0.0043 0.0139 0.0229
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Entamoeba histolytica tagatose-6-phosphate kinase, putative 0.009 0.0329 0.1622
Leishmania major pyruvate kinase 0.0067 0.0234 0.0722
Onchocerca volvulus 0.003 0.0083 0.023
Entamoeba histolytica hypothetical protein 0.004 0.0126 0.0592
Echinococcus multilocularis somatostatin receptor 0.0562 0.2251 0.2251
Brugia malayi hypothetical protein 0.0018 0.0034 0.0056
Echinococcus granulosus adenylate cyclase 0.0014 0.0018 0.0023
Loa Loa (eye worm) hypothetical protein 0.0067 0.0234 0.0571
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0144 0.0547 0.0904
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0234 0.0646
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0218 0.0391
Echinococcus granulosus sex peptide receptor 0.0562 0.2251 0.2831
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.0113 0.0142
Loa Loa (eye worm) hypoxia-induced factor 1 0.0156 0.0598 0.1457
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0562 0.2251 0.4024
Trypanosoma cruzi nucleoside transporter-like, putative 0.0086 0.0313 0.0969
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Brugia malayi Cytochrome P450 family protein 0.0054 0.0182 0.0301
Brugia malayi Sulfatase family protein 0.0018 0.0034 0.0056
Onchocerca volvulus 0.0562 0.2251 0.6211
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0598 0.2986
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Echinococcus granulosus microtubule associated protein 2 0.1384 0.5593 0.7035
Echinococcus multilocularis laminin 0.0016 0.0028 0.0028
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0026 0.0064
Chlamydia trachomatis endonuclease IV 0.0078 0.0278 0.1597
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.004 0.0126 0.0307
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.0113 0.0113
Schistosoma mansoni adenylate cyclase 0.0014 0.0018 0.0033
Echinococcus granulosus allatostatin A receptor 0.0562 0.2251 0.2831
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0307
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0156
Loa Loa (eye worm) hypothetical protein 0.0886 0.3568 0.8694
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Leishmania major cytochrome p450-like protein 0.0014 0.0021 0.005
Trichomonas vaginalis adenylate cyclase type III, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0236 0.0575
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0126 0.0592
Echinococcus granulosus neuropeptides capa receptor 0.0562 0.2251 0.2831
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Leishmania major nucleobase transporter 0.0086 0.0313 0.0969
Mycobacterium leprae Probable pyruvate kinase PykA 0.0067 0.0234 0.1708
Schistosoma mansoni cpg binding protein 0.0032 0.009 0.0161
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0126 0.0225
Echinococcus multilocularis fibrillin 1 0.0016 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0791 0.3183 0.7757
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0014 0.0021 0.0016
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0236 0.0236
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0208 0.0372
Entamoeba histolytica hypothetical protein 0.0111 0.0415 0.206
Echinococcus multilocularis high affinity choline transporter 1 0.0336 0.133 0.133
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Echinococcus multilocularis regulator of G protein signaling 0.004 0.0126 0.0126
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0218 0.0672
Trichomonas vaginalis ribokinase, putative 0.009 0.0329 0.1622
Loa Loa (eye worm) glutathione reductase 0.0049 0.0162 0.0394
Brugia malayi 6-phosphofructokinase 0.0328 0.1297 0.2143
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0126 0.0592
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0086 0.0313 0.154
Entamoeba histolytica nucleoside transporter, putative 0.0086 0.0313 0.154
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0031 0.0096
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0046 0.015 0.0189
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0156 0.0598 0.1866
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0036 0.0036
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0031 0.0083
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0031 0.0056
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0417 0.1658 0.5203
Echinococcus multilocularis neuropeptides capa receptor 0.0562 0.2251 0.2251
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0014 0.0021 0.0016
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0072 0.0318
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Onchocerca volvulus 0.0562 0.2251 0.6211
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0126 0.0126
Trichomonas vaginalis phosphofructokinase, putative 0.0328 0.1297 0.6527
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0014 0.0018 0.003
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0222 0.0866 0.0866
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei adenylyl cyclase 0.0014 0.0018 0.0042
Echinococcus granulosus intermediate filament protein 0.0054 0.0182 0.0229
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0068 0.024 0.0586
Echinococcus granulosus expressed protein 0.0784 0.3152 0.3965
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Schistosoma mansoni neuropeptide F-like receptor 0.0562 0.2251 0.4024
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Mycobacterium ulcerans hypothetical protein 0.002 0.0045 0.0163
Schistosoma mansoni aryl hydrocarbon receptor 0.005 0.0168 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Onchocerca volvulus Ribokinase homolog 0.009 0.0329 0.0908
Brugia malayi PAS domain containing protein 0.005 0.0168 0.0277
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Onchocerca volvulus 0.024 0.0938 0.2588
Trichomonas vaginalis rotamase, putative 0.0034 0.01 0.046
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0179 0.0691 0.087
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0027 0.0066
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0162 0.0493
Onchocerca volvulus 0.0103 0.0379 0.1047
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0036 0.0098
Onchocerca volvulus 0.0562 0.2251 0.6211
Trypanosoma brucei purine nucleoside transporter 0.0086 0.0313 0.0969
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0036 0.0109
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0144 0.0548 0.4156
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0014 0.0018 0.0018
Schistosoma mansoni neuropeptide receptor 0.0562 0.2251 0.4024
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0328 0.1297 1
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0068 0.0086
Trypanosoma brucei adenylyl cyclase, frameshift 0.0014 0.0018 0.0042
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0009 0.0021
Onchocerca volvulus 0.0054 0.0182 0.0503
Mycobacterium leprae possible transcriptional regulatory protein 0.0014 0.0018 0.0022
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0001 0.0001
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.024 0.0741
Echinococcus multilocularis g protein coupled receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0014 0.0018 0.0047
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0562 0.2251 0.4024
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.5203
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Brugia malayi Calcitonin receptor-like protein seb-1 0.0146 0.0557 0.092
Brugia malayi Pre-SET motif family protein 0.0418 0.1663 0.2749
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0218 0.0275
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) MH2 domain-containing protein 0.0234 0.0916 0.2232
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0379 0.0678
Schistosoma mansoni inositol transporter 0.0037 0.0113 0.0202
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0026 0.0026
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0417 0.1658 0.2086
Schistosoma mansoni growth hormone secretagogue receptor 0.0562 0.2251 0.4024
Echinococcus granulosus pseudouridine metabolizing bifunctional protein 0.009 0.0329 0.0414
Trypanosoma brucei adenylyl cyclase 0.0014 0.0018 0.0042
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0132 0.0235
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.0273 0.1073 0.3359
Mycobacterium ulcerans carbohydrate kinase CbhK 0.009 0.0329 0.1895
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0026
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0562 0.2251 0.5484
Toxoplasma gondii nucleoside transporter protein 0.0086 0.0313 0.0969
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Echinococcus granulosus retinal guanylyl cyclase 2 0.0014 0.0018 0.0023
Onchocerca volvulus 0.0562 0.2251 0.6211
Entamoeba histolytica nucleoside transporter, putative 0.0496 0.1982 1
Schistosoma mansoni neuropeptide receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0417 0.1658 0.1658
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0562 0.2251 0.4024
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Echinococcus granulosus neuropeptide Y receptor 0.0562 0.2251 0.2831
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0126 0.0126
Mycobacterium tuberculosis Probable sulfatase 0.0018 0.0034 0.012
Echinococcus multilocularis adenosine kinase 0.0791 0.3183 0.3183
Echinococcus multilocularis neuropeptide Y receptor 0.0562 0.2251 0.2251
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0008 0.0008
Loa Loa (eye worm) hypothetical protein 0.0496 0.1982 0.483
Echinococcus granulosus G protein coupled receptor 139 0.0562 0.2251 0.2831
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis lamin dm0 0.0054 0.0182 0.0182
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0086 0.0313 0.0969
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0068 0.024 0.0741
Loa Loa (eye worm) hypothetical protein 0.0017 0.0032 0.0078
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0024 0.006
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0036 0.0137
Loa Loa (eye worm) guanylyl cyclase/natriuretic peptide receptor 0.0014 0.0018 0.0044
Brugia malayi larval opioid receptor 0.0562 0.2251 0.372
Loa Loa (eye worm) TYRA-2 protein 0.0562 0.2251 0.5484
Plasmodium vivax 6-phosphofructokinase, putative 0.0089 0.0323 0.1856
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0562 0.2251 0.2251
Loa Loa (eye worm) STAT protein 0.0133 0.0504 0.1228
Trichomonas vaginalis mucin-desulfating sulfatase, putative 0.0018 0.0034 0.0125
Trypanosoma brucei adenosine transporter 2, putative 0.0086 0.0313 0.0969
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0129 0.0488 0.1519
Brugia malayi hypothetical protein 0.0025 0.0064 0.0106
Trypanosoma brucei adenylyl cyclase 0.0014 0.0018 0.0042
Echinococcus multilocularis serotonin receptor 0.0562 0.2251 0.2251
Echinococcus granulosus tm gpcr rhodopsin 0.0562 0.2251 0.2831
Giardia lamblia Hypothetical protein 0.0018 0.0034 0.0078
Schistosoma mansoni adenylate cyclase 0.0014 0.0018 0.0033
Onchocerca volvulus 0.0701 0.2816 0.7771
Brugia malayi G-protein coupled receptor 0.0562 0.2251 0.372
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0126 0.0126
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0129 0.0488 0.1519
Loa Loa (eye worm) hypothetical protein 0.0047 0.0152 0.037
Trichomonas vaginalis rotamase, putative 0.0035 0.0103 0.0477
Leishmania major inosine-guanosine transporter;with=GeneDB:LinJ36_V3.2040 0.0086 0.0313 0.0969
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0218 0.0391
Echinococcus granulosus biogenic amine 5HT receptor 0.0562 0.2251 0.2831
Schistosoma mansoni 6-phosphofructokinase 0.0328 0.1297 0.2318
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0089 0.0323 0.1856
Leishmania major nucleobase transporter 0.0086 0.0313 0.0969
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0126 0.0655
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0014 0.0021 0.002
Brugia malayi AKH receptor 0.0562 0.2251 0.372
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0236 0.0422
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0018 0.0044
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.005 0.0083
Trypanosoma cruzi nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Loa Loa (eye worm) hypothetical protein 0.0013 0.0015 0.0038
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0046 0.015 0.0189
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) melatonin receptor type 1A 0.0562 0.2251 0.5484
Mycobacterium tuberculosis Probable reductase 0.0112 0.0418 0.3123
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trypanosoma cruzi adenosine kinase, putative 0.0791 0.3183 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0036 0.0137
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0083
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0027 0.0066
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.008 0.0132
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0236 0.0422
Schistosoma mansoni inositol transporter 0.0037 0.0113 0.0202
Loa Loa (eye worm) hypothetical protein 0.065 0.2609 0.6357
Toxoplasma gondii pyruvate kinase PyKII 0.0034 0.0102 0.0305
Echinococcus granulosus geminin 0.0516 0.2063 0.2594
Trypanosoma brucei pyruvate kinase 1, putative 0.0067 0.0234 0.0722
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0129 0.0488 0.1519
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0036 0.0109
Schistosoma mansoni opsin-like receptor 0.0562 0.2251 0.4024
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0562 0.2251 0.4024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0068 0.024 0.0741
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0124 0.0468 0.3535
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0015 0.0021 0.002
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Schistosoma mansoni hypothetical protein 0.0043 0.0139 0.0248
Brugia malayi Sodium:solute symporter family protein 0.0037 0.0113 0.0187
Trichomonas vaginalis guanylate cyclase beta 1 subunit, putative 0.0014 0.0018 0.0047
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0156 0.0598 0.1866
Leishmania major receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0061 0.0208 0.0372
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0014 0.0021 0.0016
Echinococcus granulosus bloom syndrome protein 0.0022 0.005 0.0063
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0064 0.0187
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0273 0.1073 0.5395
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0078 0.0278 0.2047
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0562 0.2251 0.372
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.0273 0.1073 0.3359
Echinococcus multilocularis regulator of G protein signaling 7 0.004 0.0126 0.0126
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0562 0.2251 0.2251
Mycobacterium leprae putative cytochrome p450 0.0014 0.0021 0.0042
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0058 0.0166
Trichomonas vaginalis adenylate cyclase type, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis Ankyrin 0.0044 0.014 0.014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Echinococcus multilocularis neuropeptides capa receptor 0.0562 0.2251 0.2251
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0156 0.0598 0.1866
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0086 0.0313 0.0969
Giardia lamblia Ribokinase 0.009 0.0329 0.1583
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0042 0.0132 0.0321
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0417 0.1658 0.5203
Echinococcus granulosus retinal guanylyl cyclase 2 0.0014 0.0018 0.0023
Loa Loa (eye worm) Smad1 0.0016 0.0027 0.0066
Schistosoma mansoni adenosine kinase 0.0791 0.3183 0.5691
Plasmodium falciparum glutathione reductase 0.0017 0.0031 0.0079
Onchocerca volvulus Pyruvate kinase homolog 0.0067 0.0234 0.0646
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0042 0.0132 0.0218
Leishmania major protein kinase, putative 0.0015 0.0021 0.0051
Leishmania major trypanothione reductase 0.0049 0.0162 0.0493
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0089 0.0323 0.187
Loa Loa (eye worm) phosphofructokinase 0.0328 0.1297 0.316
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0043 0.0139 0.0139
Echinococcus granulosus 6 phosphofructokinase 0.0328 0.1297 0.1631
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0014 0.0021 0.0016
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0026 0.0061
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0562 0.2251 0.5484
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0064 0.028
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0129 0.0488 0.1519
Loa Loa (eye worm) hypothetical protein 0.0026 0.0068 0.0166
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0014 0.0018 0.0047
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0026 0.0067
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0031 0.0083
Echinococcus granulosus GPCR family 2 0.0046 0.015 0.0189
Schistosoma mansoni lamin 0.0054 0.0182 0.0326
Trypanosoma brucei expression site associated gene (ESAG) 4 protein, putative 0.0014 0.0018 0.0042
Brugia malayi hypothetical protein 0.0014 0.0018 0.003
Echinococcus granulosus peptide allatostatin:somatostatin 0.0562 0.2251 0.2831
Schistosoma mansoni netrin receptor unc5 0.0043 0.0139 0.0248
Trypanosoma brucei procyclic-enriched flagellar receptor adenylate cyclase 2 0.0014 0.0018 0.0042
Echinococcus granulosus Smad4 0.0016 0.0027 0.0034
Loa Loa (eye worm) cytochrome P450 0.0014 0.0021 0.0051
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0031 0.0083
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0008 0.001
Loa Loa (eye worm) RNA binding protein 0.0067 0.0236 0.0575
Echinococcus multilocularis fmrfamide receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0273 0.1073 0.5395
Brugia malayi Dopamine receptor 0.0562 0.2251 0.372
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0015 0.0019
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Echinococcus multilocularis lamin 0.0054 0.0182 0.0182
Giardia lamblia Pyruvate kinase 0.0034 0.0102 0.0425
Brugia malayi GH02984p 0.0336 0.133 0.2199
Trichomonas vaginalis atrial natriuretic peptide receptor, putative 0.0014 0.0018 0.0047
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0089 0.0323 0.1856
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0014 0.0021 0.002
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0014 0.0021 0.002
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.004 0.0126 0.0225
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.005 0.0208
Brugia malayi neuropeptide F receptor 0.0562 0.2251 0.372
Trichomonas vaginalis ribokinase, putative 0.009 0.0329 0.1622
Onchocerca volvulus 0.0037 0.0114 0.0315
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Mycobacterium leprae Probable conserved transmembrane protein 0.0014 0.0018 0.0022
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0031 0.0083
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0039 0.0128
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0307
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Schistosoma mansoni single-minded 0.005 0.0168 0.0299
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trypanosoma brucei adenosine transporter, putative 0.0086 0.0313 0.0969
Trichomonas vaginalis adenylate cyclase type, putative 0.0014 0.0018 0.0047
Brugia malayi G protein-coupled receptor 0.0562 0.2251 0.372
Echinococcus granulosus alpha 1A adrenergic receptor 0.0562 0.2251 0.2831
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Echinococcus granulosus serotonin receptor 0.0562 0.2251 0.2831
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0009 0.0011
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0562 0.2251 0.2831
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0016 0.0028 0.0067
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni receptor-type adenylate cyclase 0.0014 0.0018 0.0033
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0036 0.0098
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0021 0.005
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Brugia malayi Cytochrome P450 family protein 0.0024 0.0058 0.0096
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trypanosoma brucei ribokinase, putative 0.009 0.0329 0.102
Brugia malayi TAR-binding protein 0.0067 0.0236 0.039
Onchocerca volvulus 0.009 0.0329 0.0908
Trypanosoma brucei unspecified product 0.0086 0.0313 0.0969
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0014 0.0021 0.002
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Echinococcus granulosus beta-adrenergic receptor kinase 0.0042 0.0132 0.0166
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0103 0.0477
Echinococcus granulosus cytochrome P450 2K1 0.0014 0.0021 0.0026
Plasmodium vivax 6-phosphofructokinase, putative 0.0089 0.0323 0.1856
Loa Loa (eye worm) hypothetical protein 0.0336 0.133 0.3242
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0064 0.0187
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0024 0.006
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0598 0.2986
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0562 0.2251 0.372
Echinococcus granulosus tm gpcr rhodopsin 0.0562 0.2251 0.2831
Plasmodium vivax thioredoxin reductase, putative 0.0049 0.0162 0.0875
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0068 0.024 0.0302
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Brugia malayi PXA domain containing protein 0.004 0.0126 0.0208
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0013 0.0021
Echinococcus granulosus axis inhibition protein axin 0.004 0.0126 0.0158
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0027 0.0072 0.0318
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0156 0.0598 0.1866
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0562 0.2251 0.2251
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0014 0.0021 0.0016
Toxoplasma gondii adenylate cyclase, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.005 0.0208
Toxoplasma gondii pyruvate kinase PyK1 0.0067 0.0234 0.0722
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.0417 0.1658 1
Schistosoma mansoni hypothetical protein 0.0014 0.0018 0.0033
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.002 0.0045 0.0163
Entamoeba histolytica phosphofructokinase, putative 0.0328 0.1297 0.6527
Leishmania major receptor-type adenylate cyclase b 0.0014 0.0018 0.0042
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0036 0.0109
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0064 0.028
Echinococcus multilocularis pyruvate kinase 0.0034 0.0102 0.0102
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0086 0.0313 0.154
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0306
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0039
Trypanosoma cruzi adenosine kinase, putative 0.009 0.0329 0.102
Trypanosoma brucei adenosine transporter, putative 0.0086 0.0313 0.0969
Brugia malayi phosphofructokinase 0.0328 0.1297 0.2143
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0562 0.2251 0.2251
Echinococcus multilocularis adenylate cyclase 9 0.0325 0.1283 0.1283
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Schistosoma mansoni axis inhibition protein axin 0.004 0.0126 0.0225
Trypanosoma brucei protein kinase, putative 0.0156 0.0598 0.1866
Echinococcus multilocularis tumor protein p63 0.0701 0.2814 0.2814
Onchocerca volvulus Adenylate cyclase type 3 homolog 0.09 0.3624 1
Echinococcus granulosus adenosine kinase 0.0791 0.3183 0.4004
Echinococcus granulosus tachykinin peptides receptor 99D 0.0562 0.2251 0.2831
Schistosoma mansoni biogenic amine (5HT) receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) G-protein coupled receptor 0.0562 0.2251 0.5484
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0014 0.0021 0.005
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0014 0.0018 0.005
Brugia malayi Smad1 0.0016 0.0027 0.0045
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0126 0.0592
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.0129 0.0488 0.1519
Brugia malayi Adenosine kinase-like 0.0791 0.3183 0.5261
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0014 0.0021 0.0016
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0067 0.0234 0.1689
Leishmania major receptor-type adenylate cyclase a 0.0014 0.0018 0.0042
Entamoeba histolytica fructokinase, putative 0.009 0.0329 0.1622
Trypanosoma brucei adenosine transporter 2, putative 0.0086 0.0313 0.0969
Leishmania major receptor-type adenylate cyclase b 0.0014 0.0018 0.0042
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0012 0.0012 0.0022
Echinococcus multilocularis neuropeptide receptor 0.0562 0.2251 0.2251
Echinococcus multilocularis 6 phosphofructokinase 0.0328 0.1297 0.1297
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0562 0.2251 0.2831
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0014 0.0021 0.0016
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.0417 0.1658 0.5203
Echinococcus granulosus pyruvate kinase 0.0067 0.0234 0.0295
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Echinococcus multilocularis adenylate cyclase 9 0.0014 0.0018 0.0018
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0043 0.0139 0.0338
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni egf-like domain protein 0.0016 0.0028 0.0049
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0031 0.0159
Echinococcus granulosus regulator of G protein signaling 3 0.004 0.0126 0.0158
Toxoplasma gondii phosphofructokinase PFKII 0.0089 0.0323 0.1
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0089 0.0323 0.159
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0035 0.0103 0.0251
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0015 0.0019
Echinococcus multilocularis axis inhibition protein axin 0.004 0.0126 0.0126
Schistosoma mansoni regulator of G protein signaling 0.004 0.0126 0.0225
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Giardia lamblia Hypothetical protein 0.0496 0.1982 1
Echinococcus multilocularis Smad4 0.0016 0.0027 0.0027
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0061 0.0208 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0417 0.1658 0.8353
Brugia malayi Adenylyl cyclase protein 0.0325 0.1283 0.2121
Schistosoma mansoni pyruvate kinase 0.0067 0.0234 0.0419
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trypanosoma cruzi pyruvate kinase 2, putative 0.0067 0.0234 0.0722
Echinococcus multilocularis equilibrative nucleoside transporter 3 0.041 0.1631 0.1631
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0562 0.2251 0.372
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0015 0.0021 0.0051
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0417 0.1658 0.2965
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0031 0.0113
Brugia malayi Melatonin receptor type 1A 0.0562 0.2251 0.372
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0014 0.0021 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0064 0.028
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Plasmodium vivax pyruvate kinase, putative 0.0067 0.0234 0.1317
Echinococcus granulosus retinal guanylyl cyclase 2 0.0014 0.0018 0.0023
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0562 0.2251 0.4024
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0126 0.0208
Mycobacterium ulcerans arylsulfatase AtsB 0.0018 0.0034 0.0094
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0031 0.0079
Schistosoma mansoni sodium/solute symporter 0.0037 0.0113 0.0202
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Trichomonas vaginalis adenylate cyclase type VI, putative 0.0014 0.0018 0.0047
Brugia malayi Pyruvate kinase, M2 isozyme 0.0067 0.0234 0.0387
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Mycobacterium ulcerans arylsulfatase AtsD 0.0018 0.0034 0.0094
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0014 0.0021 0.002
Trichomonas vaginalis adenylate cyclase type III, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.0273 0.1073 0.1073
Trypanosoma brucei adenosine transporter 2 0.0086 0.0313 0.0969
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis neuropeptide s receptor 0.104 0.4194 0.4194
Trypanosoma brucei nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, frameshift 0.0014 0.0018 0.0042
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.0417 0.1658 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0015 0.0015
Trichomonas vaginalis atrial natriuretic peptide receptor, putative 0.0014 0.0018 0.0047
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0417 0.1658 0.5203
Trichomonas vaginalis intestinal guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus granulosus mitogen activated protein kinase 3 0.0156 0.0598 0.0752
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0562 0.2251 0.4024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Brugia malayi Pax transcription factor protein 2 0.024 0.0938 0.155
Onchocerca volvulus 0.0325 0.1283 0.3541
Trichomonas vaginalis adenylate cyclase type, putative 0.0014 0.0018 0.0047
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0112 0.0418 0.3123
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.0417 0.1658 0.2086
Trypanosoma brucei trypanothione reductase 0.0049 0.0162 0.0493
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0014 0.0021 0.002
Giardia lamblia Pyruvate kinase 0.0067 0.0234 0.11
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.0288 0.1133 0.2761
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0562 0.2251 0.4024
Echinococcus multilocularis mitogen activated protein kinase 3 0.0156 0.0598 0.0598
Echinococcus multilocularis RUN 0.004 0.0126 0.0126
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Echinococcus granulosus tm gpcr rhodopsin 0.0562 0.2251 0.2831
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0014 0.0021 0.0016
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0031 0.0083
Schistosoma mansoni regulator of G protein signaling 0.004 0.0126 0.0225
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.5203
Trypanosoma brucei procyclic-enriched flagellar receptor adenylate cyclase 1 0.0014 0.0018 0.0042
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.002 0.0045 0.0074
Schistosoma mansoni microtubule-associated protein tau 0.1384 0.5593 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0036 0.0088
Loa Loa (eye worm) neuropeptide F receptor 0.0562 0.2251 0.5484
Schistosoma mansoni neuropeptide receptor 0.0562 0.2251 0.4024
Plasmodium falciparum pyruvate kinase 2 0.0034 0.0102 0.0509
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0058 0.0141
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0026 0.0048
Mycobacterium ulcerans arylsulfatase AtsD 0.0018 0.0034 0.0094
Mycobacterium ulcerans 6-phosphofructokinase 0.0328 0.1297 0.7795
Echinococcus granulosus neuropeptide s receptor 0.104 0.4194 0.5275
Brugia malayi MH1 domain containing protein 0.0016 0.0027 0.0045
Trypanosoma brucei adenosine transporter 2, putative 0.0086 0.0313 0.0969
Trypanosoma brucei adenylyl cyclase 0.0014 0.0018 0.0042
Trichomonas vaginalis adenylate cyclase type III, putative 0.0014 0.0018 0.0047
Echinococcus granulosus biogenic amine 5HT receptor 0.0562 0.2251 0.2831
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0014 0.0021 0.002
Schistosoma mansoni cytochrome P450 0.0014 0.0021 0.0037
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0031 0.0083
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0058 0.0197 0.0247
Brugia malayi Ribokinase 0.009 0.0329 0.0544
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0018 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0015 0.0033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0218 0.1221
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0014 0.0018 0.0047
Echinococcus granulosus 7tm_1 domain containing protein 0.0562 0.2251 0.2831
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0146 0.0557 0.092
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Brugia malayi G-protein coupled receptor 0.0562 0.2251 0.372
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Brugia malayi hypothetical protein 0.0169 0.0651 0.1077
Schistosoma mansoni cpg binding protein 0.003 0.0083 0.0149
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0146 0.0557 0.1356
Loa Loa (eye worm) hypothetical protein 0.0054 0.0182 0.0444
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0015 0.0015
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0068 0.0068
Brugia malayi bHLH-PAS transcription factor 0.0037 0.0114 0.0189
Schistosoma mansoni biogenic amine (5HT) receptor 0.0562 0.2251 0.4024
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0018 0.0047
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.0113 0.034
Onchocerca volvulus 0.0054 0.0182 0.0503
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Schistosoma mansoni amine GPCR 0.0562 0.2251 0.4024
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0015 0.0033
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus granulosus pyruvate kinase 0.0034 0.0102 0.0128
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0014 0.0021 0.0016
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Onchocerca volvulus 0.0562 0.2251 0.6211
Trypanosoma brucei pyruvate kinase 1 0.0067 0.0234 0.0722
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0034 0.01 0.0298
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0027 0.0048
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0014 0.0021 0.0016
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.0417 0.1658 0.5203
Trichomonas vaginalis phosphofructokinase, putative 0.0089 0.0323 0.159
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Giardia lamblia Kinase, CMGC MAPK 0.0156 0.0598 0.2953
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.0113 0.0113
Schistosoma mansoni pyruvate kinase 0.0034 0.0102 0.0182
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0014 0.0021 0.002
Trichomonas vaginalis guanylate cyclase, putative 0.0027 0.0072 0.0318
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Schistosoma mansoni regulator of G protein signaling 0.004 0.0126 0.0225
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0179 0.0691 0.0691
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Onchocerca volvulus 0.0562 0.2251 0.6211
Schistosoma mansoni polycystin 1-related 0.004 0.0126 0.0225
Loa Loa (eye worm) hypothetical protein 0.004 0.0126 0.0307
Onchocerca volvulus 0.0014 0.0018 0.005
Echinococcus multilocularis transcription factor Dp 1 0.004 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0061 0.0208 0.0372
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0058 0.0141
Loa Loa (eye worm) hypothetical protein 0.0016 0.0028 0.0067
Loa Loa (eye worm) G-protein coupled receptor 0.0562 0.2251 0.5484
Leishmania major ribokinase, putative 0.009 0.0329 0.102
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Brugia malayi glutathione reductase 0.0049 0.0162 0.0267
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0234 0.1142
Schistosoma mansoni smad1 5 8 and 0.0016 0.0027 0.0048
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0156
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Echinococcus granulosus Tolloid protein 1 0.0016 0.0028 0.0035
Trichomonas vaginalis ribokinase, putative 0.009 0.0329 0.1622
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0234 0.0571
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0072 0.0318
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0026 0.0067
Trypanosoma brucei adenylyl cyclase 0.0014 0.0018 0.0042
Schistosoma mansoni ribokinase 0.009 0.0329 0.0588
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0016 0.0028 0.0049
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0031 0.0083
Schistosoma mansoni loxhd1 0.004 0.0126 0.0225
Trypanosoma cruzi nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Schistosoma mansoni rab6-interacting 0.004 0.0126 0.0225
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0126 0.0592
Onchocerca volvulus Putative pyridoxal kinase 0.009 0.0329 0.0908
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0015 0.0038
Trypanosoma cruzi nucleobase transporter, putative 0.0086 0.0313 0.0969
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis phosphofructokinase, putative 0.0089 0.0323 0.159
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0034 0.01 0.0298
Echinococcus granulosus rhodopsin orphan GPCR 0.0562 0.2251 0.2831
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0144 0.0547 0.2727
Echinococcus granulosus dro:myosuppressin receptor 0.0562 0.2251 0.2831
Schistosoma mansoni hypothetical protein 0.0014 0.0018 0.0033
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0598 0.2986
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0132 0.0235
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0562 0.2251 0.4024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0031 0.0102
Brugia malayi hypothetical protein 0.009 0.0329 0.0544
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.0201 0.0616
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0018 0.0047
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0036 0.0137
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Entamoeba histolytica Hypothetical protein T24C12.3, putative 0.009 0.0329 0.1622
Echinococcus granulosus pyruvate kinase 0.0067 0.0234 0.0295
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trichomonas vaginalis pyruvate kinase, putative 0.0067 0.0234 0.1142
Toxoplasma gondii adenylate and guanylate cyclase catalytic domain-containing protein 0.0014 0.0018 0.0042
Plasmodium vivax glutathione reductase, putative 0.0049 0.0162 0.0875
Echinococcus granulosus high affinity choline transporter 1 0.0336 0.133 0.1673
Echinococcus granulosus lamin 0.0054 0.0182 0.0229
Loa Loa (eye worm) hypothetical protein 0.0016 0.0028 0.0067
Entamoeba histolytica pyruvate kinase, putative 0.0047 0.0152 0.0724
Echinococcus granulosus netrin receptor unc 5 0.0043 0.0139 0.0174
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Onchocerca volvulus 0.0562 0.2251 0.6211
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0014 0.0021 0.002
Brugia malayi hypothetical protein 0.004 0.0126 0.0208
Leishmania major receptor-type adenylate cyclase a-like protein 0.0014 0.0018 0.0042
Leishmania major tagatose-6-phosphate kinase-like protein 0.009 0.0329 0.102
Trypanosoma cruzi nucleobase transporter, putative 0.0086 0.0313 0.0969
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0036 0.006
Brugia malayi Cytochrome P450 family protein 0.0024 0.0058 0.0096
Echinococcus multilocularis mitogen activated protein kinase 0.0156 0.0598 0.0598
Trypanosoma cruzi adenosine kinase, putative 0.009 0.0329 0.102
Trichomonas vaginalis set domain proteins, putative 0.0476 0.1898 0.9573
Brugia malayi ORL1-like opioid receptor 0.0562 0.2251 0.372
Trypanosoma brucei nucleobase/nucleoside transporter 8.1 0.0086 0.0313 0.0969
Toxoplasma gondii calcium binding egf domain-containing protein 0.0016 0.0028 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Leishmania major adenosine kinase-like protein 0.009 0.0329 0.102
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0014 0.0021 0.002
Echinococcus multilocularis geminin 0.0516 0.2063 0.2063
Schistosoma mansoni protein tyrosine kinase 0.0014 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.01 0.0369 0.0898
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0562 0.2251 0.2831
Schistosoma mansoni 6-phosphofructokinase 0.0328 0.1297 0.2318
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Echinococcus granulosus neuropeptide receptor A26 0.104 0.4194 0.5275
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0031 0.0083
Brugia malayi MH2 domain containing protein 0.0234 0.0916 0.1514
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trichomonas vaginalis CMGC family protein kinase 0.0156 0.0598 0.2986
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0026 0.0026
Trypanosoma cruzi adenosine kinase, putative 0.0791 0.3183 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0112 0.0418 0.3123
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0156 0.0598 0.1866
Onchocerca volvulus 0.0013 0.0015 0.0043
Echinococcus granulosus 7TM GPCR rhodopsin 0.0562 0.2251 0.2831
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Entamoeba histolytica kinase, PfkB family 0.009 0.0329 0.1622
Echinococcus granulosus equilibrative nucleoside transporter 0.0496 0.1982 0.2493
Brugia malayi Serotonin receptor 0.1496 0.605 1
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0014 0.0021 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0014 0.0021 0.005
Echinococcus multilocularis pyruvate kinase 0.0034 0.0102 0.0102
Trypanosoma brucei receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0044
Schistosoma mansoni hypothetical protein 0.0046 0.015 0.0268
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.0113 0.0142
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0014 0.0021 0.0016
Toxoplasma gondii guanylyl cyclase 0.0014 0.0018 0.0042
Echinococcus multilocularis atrial natriuretic peptide receptor 1 0.0014 0.0018 0.0018
Echinococcus multilocularis adenylate cyclase type IX 0.0014 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Brugia malayi follicle stimulating hormone receptor 0.1018 0.4104 0.6782
Schistosoma mansoni ankyrin 23/unc44 0.0043 0.0139 0.0248
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0144 0.0548 0.4143
Mycobacterium leprae conserved hypothetical protein 0.002 0.0045 0.0231
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0156 0.0598 0.1866
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0126 0.0592
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0562 0.2251 0.372
Trichomonas vaginalis adenylyl cyclase type V, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) pyruvate kinase 0.0067 0.0234 0.0571
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0014 0.0018 0.0047
Mycobacterium ulcerans epimerase 0.002 0.0045 0.0163
Toxoplasma gondii 6-phosphofructokinase 0.0089 0.0323 0.1
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Mycobacterium tuberculosis Probable dehydrogenase 0.0112 0.0418 0.3123
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0012 0.0009 0.0013
Brugia malayi A-kinase anchor protein 10, precursor 0.004 0.0126 0.0208
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0014 0.0018 0.0047
Brugia malayi Guanylyl cyclase protein 23 0.0014 0.0018 0.003
Brugia malayi hypoxia-induced factor 1 0.0156 0.0598 0.0988
Echinococcus granulosus fmrfamide receptor 0.0562 0.2251 0.2831
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.0113 0.0113
Loa Loa (eye worm) RecQ helicase 0.0022 0.005 0.0122
Schistosoma mansoni hypothetical protein 0.0111 0.0415 0.0743
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0182 0.0444
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0014 0.0018 0.003
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0031 0.0079
Brugia malayi Fibulin-1 precursor 0.0016 0.0028 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Brugia malayi hypothetical protein 0.004 0.0126 0.0208
Echinococcus multilocularis rhodopsin orphan GPCR 0.0562 0.2251 0.2251
Echinococcus multilocularis pyruvate kinase 0.0034 0.0102 0.0102
Brugia malayi Latrophilin receptor protein 2 0.0046 0.015 0.0248
Echinococcus multilocularis conserved hypothetical protein 0.1401 0.5662 0.5662
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0562 0.2251 0.372
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0014 0.0018 0.0047
Schistosoma mansoni hypothetical protein 0.0014 0.0018 0.0033
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0026 0.0047
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus granulosus thioredoxin glutathione reductase 0.0049 0.0162 0.0203
Brugia malayi Receptor family ligand binding region containing protein 0.0014 0.0018 0.003
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.0417 0.1658 0.2965
Schistosoma mansoni pyruvate kinase 0.0067 0.0234 0.0419
Chlamydia trachomatis pyruvate kinase 0.0067 0.0234 0.1332
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0025 0.0066 0.016
Echinococcus granulosus Regulator of G protein signaling 20 0.004 0.0126 0.0158
Schistosoma mansoni biogenic amine receptor 0.0562 0.2251 0.4024
Onchocerca volvulus 0.0562 0.2251 0.6211
Echinococcus granulosus pyruvate kinase 0.0034 0.0102 0.0128
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0562 0.2251 0.4024
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0014 0.0021 0.0016
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0014 0.0021 0.0016
Mycobacterium ulcerans sulfatase 0.0018 0.0034 0.0094
Trichomonas vaginalis conserved hypothetical protein 0.009 0.0329 0.1622
Echinococcus granulosus g protein coupled receptor 0.0562 0.2251 0.2831
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0058 0.0166
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Trypanosoma cruzi nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0415 0.0743
Trypanosoma brucei adenylyl cyclase 0.0014 0.0018 0.0042
Onchocerca volvulus 0.004 0.0126 0.0347
Loa Loa (eye worm) 6-phosphofructokinase 0.0328 0.1297 0.316
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.0273 0.1073 0.5369
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0112 0.0418 0.3139
Echinococcus granulosus transcription factor Dp 1 0.004 0.0123 0.0155
Toxoplasma gondii nucleoside transporter protein 0.0086 0.0313 0.0969
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0018 0.0044
Echinococcus granulosus receptor type guanylyl cyclase 0.0014 0.0018 0.0023
Brugia malayi pyruvate kinase 0.0014 0.0019 0.0032
Echinococcus multilocularis thioredoxin glutathione reductase 0.0049 0.0162 0.0162
Trypanosoma brucei nucleobase/nucleoside transporter 8.1, putative 0.0086 0.0313 0.0969
Echinococcus multilocularis receptor type guanylyl cyclase 0.0014 0.0018 0.0018
Trypanosoma brucei expression site-associated gene 4 (ESAG4) protein, putative 0.0014 0.0018 0.0042
Echinococcus granulosus solute carrier family 5 0.0037 0.0113 0.0142
Plasmodium falciparum thioredoxin reductase 0.0017 0.0031 0.0079
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.002 0.0044 0.0073
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0089 0.0323 0.1
Entamoeba histolytica phosphofructokinase, putative 0.0328 0.1297 0.6527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0064 0.0187
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0328 0.1297 0.4065
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0026 0.0067
Brugia malayi hypothetical protein 0.0086 0.0313 0.0517
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.0417 0.1658 0.5203
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0236 0.039
Schistosoma mansoni lipoxygenase 0.0179 0.0691 0.1236
Echinococcus granulosus death domain containing protein 0.0043 0.0139 0.0174
Mycobacterium tuberculosis Adenosine kinase 0.009 0.0329 0.2431
Echinococcus multilocularis expressed protein 0.0784 0.3152 0.3152
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.0417 0.1658 1
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.004 0.0126 0.0126
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Leishmania major pyruvate kinase 0.0067 0.0234 0.0722
Entamoeba histolytica hypothetical protein 0.004 0.0126 0.0592
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0418 0.1663 0.4053
Schistosoma mansoni neuropeptide F-like receptor 0.0562 0.2251 0.4024
Schistosoma mansoni amine GPCR 0.0562 0.2251 0.4024
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0036 0.0139
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0328 0.1297 0.7795
Plasmodium falciparum glutathione reductase 0.0049 0.0162 0.0875
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0086 0.0313 0.154
Leishmania major nucleoside transporter 1, putative 0.0086 0.0313 0.0969
Trichomonas vaginalis guanylate cyclase beta 2 subunit, putative 0.0014 0.0018 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.001 0.0001 0.0002
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0016 0.0028 0.0067
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0014 0.0021 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0034 0.0082
Echinococcus multilocularis Regulator of G protein signaling 20 0.004 0.0126 0.0126
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0014 0.0021 0.002
Schistosoma mansoni myosin xvIII 0.0562 0.2251 0.4024
Onchocerca volvulus Netrin receptor homolog 0.0043 0.0139 0.0382
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0562 0.2251 0.2251
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0218 0.1221
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni biogenic amine receptor 0.0562 0.2251 0.4024
Onchocerca volvulus 0.0562 0.2251 0.6211
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0126 0.0158
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0025 0.0066 0.0108
Mycobacterium tuberculosis Possible arylsulfatase AtsA (aryl-sulfate sulphohydrolase) (arylsulphatase) 0.0018 0.0034 0.012
Echinococcus multilocularis allatostatin A receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0026 0.0067
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Schistosoma mansoni ap endonuclease 0.0018 0.0036 0.0065
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0273 0.1073 0.2616
Onchocerca volvulus Arrow homolog 0.0025 0.0066 0.0181
Echinococcus multilocularis dro:myosuppressin receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0417 0.1658 0.2741
Toxoplasma gondii calcium binding egf domain-containing protein 0.0016 0.0028 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Brugia malayi Adenylate and Guanylate cyclase catalytic domain containing protein 0.0014 0.0018 0.003
Toxoplasma gondii peptidylprolyl isomerase 0.0034 0.01 0.0298
Trypanosoma brucei adenosine transporter 2 0.0086 0.0313 0.0969
Leishmania major cytochrome p450-like protein 0.0024 0.0058 0.0166
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0014 0.0021 0.002
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0014 0.0021 0.0016
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0036 0.0109
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0043 0.0139 0.0174
Leishmania major adenylate cyclase-like protein 0.0014 0.0018 0.0042
Onchocerca volvulus 0.0562 0.2251 0.6211
Schistosoma mansoni hypothetical protein 0.0562 0.2251 0.4024
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Brugia malayi hypothetical protein 0.004 0.0126 0.0208
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0027 0.0034
Echinococcus granulosus g protein coupled receptor 0.0562 0.2251 0.2831
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0328 0.1297 0.4065
Echinococcus multilocularis regulator of G protein signaling 3 0.004 0.0126 0.0126
Loa Loa (eye worm) hypothetical protein 0.009 0.0329 0.0802
Echinococcus multilocularis neuropeptide receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis retinal guanylate cyclase, putative 0.0014 0.0018 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0228 0.0408
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0562 0.2251 0.4024
Loa Loa (eye worm) hypothetical protein 0.0496 0.1982 0.483
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0058 0.0166
Schistosoma mansoni smad1 5 8 and 0.0016 0.0027 0.0048
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0064 0.0187
Echinococcus multilocularis orexin receptor type 2 0.0562 0.2251 0.2251
Trichomonas vaginalis phosphofructokinase, putative 0.0328 0.1297 0.6527
Giardia lamblia Hypothetical protein 0.0018 0.0034 0.0078
Leishmania major adenosine kinase, putative 0.0791 0.3183 1
Brugia malayi MAP kinase sur-1 0.0156 0.0598 0.0989
Echinococcus multilocularis pyruvate kinase 0.0053 0.0177 0.0177
Mycobacterium ulcerans arylsulfatase, AslA 0.0018 0.0034 0.0094
Schistosoma mansoni adenosine kinase 0.0791 0.3183 0.5691
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0417 0.1658 0.5203
Echinococcus multilocularis serotonin receptor 0.0562 0.2251 0.2251
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0014 0.0018 0.0018
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Brugia malayi Dopamine receptor protein 1 0.0562 0.2251 0.372
Onchocerca volvulus 0.0476 0.1899 0.5241
Mycobacterium tuberculosis Probable oxidoreductase 0.0124 0.0468 0.3521
Trypanosoma brucei Adenylate and Guanylate cyclase catalytic domain containing protein, putative 0.0014 0.0018 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.014 0.0341
Entamoeba histolytica hypothetical protein 0.004 0.0126 0.0592
Brugia malayi G protein-coupled receptor F59B2.13 0.0562 0.2251 0.372
Trypanosoma brucei adenosine kinase, putative 0.0791 0.3183 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0028 0.0067
Loa Loa (eye worm) hypothetical protein 0.0061 0.0208 0.0508
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Schistosoma mansoni hypothetical protein 0.0562 0.2251 0.4024
Mycobacterium tuberculosis Possible hydrolase 0.0018 0.0034 0.012
Trichomonas vaginalis adenylate cyclase type IX, putative 0.0014 0.0018 0.0047
Echinococcus granulosus single minded 2 0.0037 0.0114 0.0144
Echinococcus granulosus regulator of G protein signaling 7 0.004 0.0126 0.0158
Schistosoma mansoni high-affinity choline transporter 0.0336 0.133 0.2379
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.0417 0.1658 0.5203
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis equilibrative nucleoside transporter, putative 0.0086 0.0313 0.154
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0045 0.021
Brugia malayi Pre-SET motif family protein 0.0061 0.0208 0.0344
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0014 0.0021 0.0016
Loa Loa (eye worm) RGC/RGC protein kinase 0.0014 0.0018 0.0044
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0014 0.0021 0.002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0027 0.0027
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0015 0.0021 0.0051
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.5203
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0034 0.0125
Loa Loa (eye worm) hypothetical protein 0.0018 0.0034 0.0082
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Brugia malayi Regulator of G protein signaling domain containing protein 0.004 0.0126 0.0208
Brugia malayi MH2 domain containing protein 0.0016 0.0027 0.0045
Brugia malayi intermediate filament protein 0.0054 0.0182 0.0301
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Mycobacterium tuberculosis 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) 0.009 0.0329 0.2431
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Mycobacterium leprae conserved hypothetical protein 0.0014 0.0018 0.0022
Brugia malayi hypothetical protein 0.0111 0.0415 0.0686
Plasmodium vivax pyruvate kinase 2, putative 0.0034 0.0102 0.0509
Brugia malayi hypothetical protein 0.0496 0.1982 0.3276
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Trypanosoma cruzi receptor-type adenylate cyclase, putative 0.0014 0.0018 0.0042
Brugia malayi MH1 domain containing protein 0.0016 0.0027 0.0045
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0124 0.0468 0.3521
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0157
Loa Loa (eye worm) hypothetical protein 0.0037 0.0113 0.0275
Leishmania major receptor-type adenylate cyclase b 0.0014 0.0018 0.0042
Echinococcus multilocularis bloom syndrome protein 0.0022 0.005 0.005
Leishmania major receptor-type adenylate cyclase b 0.0014 0.0018 0.0042
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0027 0.0072 0.0318
Echinococcus granulosus mitogen activated protein kinase 0.0156 0.0598 0.0752
Onchocerca volvulus 0.0311 0.1227 0.3386
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0415 0.0522
Mycobacterium leprae Conserved hypothetical protein 0.0014 0.0021 0.0042
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0156 0.0598 0.1458
Trypanosoma brucei adenosine kinase, putative 0.0791 0.3183 1
Echinococcus multilocularis 0.0014 0.0021 0.0021
Echinococcus granulosus g protein coupled receptor 0.0562 0.2251 0.2831
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Trichomonas vaginalis adenylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus granulosus atrial natriuretic peptide receptor 1 0.0014 0.0018 0.0023
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0014 0.0021 0.005
Brugia malayi Immunoglobulin I-set domain containing protein 0.0043 0.0139 0.0229
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0078 0.0278 0.1582
Echinococcus granulosus hypothetical protein 0.1963 0.795 1
Echinococcus granulosus axis inhibition protein axin 0.004 0.0126 0.0158
Echinococcus multilocularis ribokinase 0.009 0.0329 0.0329
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0562 0.2251 0.2251
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0236 0.0422
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0562 0.2251 0.2251
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis neuropeptide Y receptor 0.0562 0.2251 0.2251
Trichomonas vaginalis phosphofructokinase, putative 0.0328 0.1297 0.6527
Entamoeba histolytica hypothetical protein 0.0111 0.0415 0.206
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0182 0.0301
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0058 0.0141
Trichomonas vaginalis guanylate cyclase, putative 0.0014 0.0018 0.0047
Echinococcus multilocularis retinal guanylyl cyclase 2 0.0014 0.0018 0.0018
Schistosoma mansoni hypothetical protein 0.0014 0.0021 0.0037
Echinococcus granulosus nuclear factor of activated T cells 5 0.0222 0.0866 0.109
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0078 0.0278 0.0459
Brugia malayi hypothetical protein 0.0562 0.2251 0.372
Brugia malayi Protein kinase domain containing protein 0.0045 0.0144 0.0239
Echinococcus granulosus neuropeptide FF receptor 2 0.0562 0.2251 0.2831
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0017 0.0031 0.0159
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.0113 0.0142
Schistosoma mansoni soluble guanylate cyclase gcy 0.0014 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.0562 0.2251 0.5484
Brugia malayi putative neuropeptide receptor NPR1 0.0562 0.2251 0.372
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.0417 0.1658 0.836
Leishmania major cytochrome p450-like protein 0.0014 0.0021 0.005
Toxoplasma gondii nucleoside transporter protein 0.0086 0.0313 0.0969
Echinococcus multilocularis g-protein coupled receptor 0.0562 0.2251 0.2251
Schistosoma mansoni alpha-1 adrenergic receptor 0.0562 0.2251 0.4024
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.0273 0.1073 0.2616
Trypanosoma brucei procyclic-enriched flagellar receptor adenylate cyclase 6 0.0014 0.0018 0.0042
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0013 0.0021
Loa Loa (eye worm) cytochrome P450 family protein 0.0054 0.0182 0.0443
Trypanosoma brucei receptor-type adenylate cyclase GRESAG 4, putative 0.0014 0.0018 0.0042
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0126 0.0126
Brugia malayi MH2 domain containing protein 0.0016 0.0027 0.0045

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) > 5 uM In vitro anticoagulant potency measured in human plasma by thrombin generation (TG) assay expressed as 2 x TG ChEMBL. 14980670
Activity (functional) > 5 uM In vitro anticoagulant potency measured in human plasma by thrombin generation (TG) assay expressed as 2 x TG ChEMBL. 14980670
IC50 (binding) = 3 nM Inhibitory concentration against human Coagulation factor X ChEMBL. 14980670
IC50 (binding) = 3 nM Inhibitory concentration against human Coagulation factor X ChEMBL. 14980670
Ki (binding) = 3.4 nM Binding affinity against Coagulation factor X ChEMBL. 14980670
Ki (binding) = 3.4 nM Binding affinity against Coagulation factor X ChEMBL. 14980670

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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