TDR Targets

Basic information

Technical information

TDR Targets ID: 236733
Name: N-[(3-chlorophenyl)methyl]-N-methylnitrous am ide
MW: 184.623 | Formula: C8H9ClN2O
H donors: 0 H acceptors: 1 LogP: 2.31 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: O=NN(Cc1cccc(c1)Cl)C
InChi: 1S/C8H9ClN2O/c1-11(10-12)6-7-3-2-4-8(9)5-7/h2-5H,6H2,1H3
InChiKey: YALMLCXXHQHFJI-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

N-[(3-chlorophenyl)methyl]-N-methyl-nitrous amide
N-(3-chlorobenzyl)-N-methyl-nitrous amide
98736-46-0
CCRIS 2564
N-Nitroso-N-(3-chlorobenzyl)methylamine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	Hsp90 protein	0.0035	0.0059	0.0059
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0038	0.0069	0.1294
Trypanosoma cruzi	heat shock protein 85, putative	0.0045	0.0093	0.0206
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0051	0.0115	0.4406
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Mycobacterium leprae	PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)	0.0049	0.0109	0.5
Trypanosoma brucei	heat shock protein 90, putative	0.0052	0.012	0.016
Trypanosoma brucei	Heat shock protein 83, putative	0.0052	0.012	0.016
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0051	0.0115	0.4406
Echinococcus multilocularis	expressed protein	0.0038	0.007	0.27
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0051	0.0115	0.4406
Echinococcus multilocularis	endoplasmin	0.0049	0.0109	0.4171
Schistosoma mansoni	chromobox protein	0.0067	0.0172	0.661
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Trichomonas vaginalis	chromobox protein, putative	0.0041	0.0079	0.2107
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Schistosoma mansoni	endoplasmin	0.0052	0.012	0.4602
Trichomonas vaginalis	endoplasmin, putative	0.0038	0.007	0.171
Trypanosoma cruzi	heat shock protein 90, putative	0.0052	0.012	0.0274
Echinococcus multilocularis	tar DNA binding protein	0.0073	0.019	0.7286
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0057	0.0136	0.0136
Echinococcus granulosus	heat shock protein heat shock protein 90 alpha	0.0045	0.0093	0.3588
Trichomonas vaginalis	chromobox protein, putative	0.0067	0.0172	0.6163
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0093	0.0261	1
Trichomonas vaginalis	CAMK family protein kinase	0.0046	0.0097	0.2902
Trichomonas vaginalis	chromobox protein, putative	0.0041	0.0079	0.2107
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Loa Loa (eye worm)	RNA binding protein	0.0073	0.019	0.019
Echinococcus granulosus	chromobox protein 1	0.0067	0.0172	0.661
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Giardia lamblia	Kinase, PLK	0.0093	0.0261	1
Echinococcus granulosus	heat shock protein 75 kDa mitochondrial	0.0035	0.0059	0.2246
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Schistosoma mansoni	heat shock protein	0.0052	0.012	0.4602
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Entamoeba histolytica	heat shock protein 90, putative	0.0052	0.012	0.3038
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Echinococcus granulosus	endoplasmin	0.0049	0.0109	0.4171
Schistosoma mansoni	hypothetical protein	0.0039	0.0073	0.2803
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Schistosoma mansoni	tar DNA-binding protein	0.0073	0.019	0.7286
Onchocerca volvulus	Heat shock protein 75 kDa, mitochondrial homolog	0.0035	0.0059	0.0823
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0069	0.1672
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0051	0.0115	0.0115
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Loa Loa (eye worm)	heat shock protein 90	0.0052	0.012	0.012
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Trypanosoma cruzi	polo-like protein kinase, putative	0.0093	0.0261	0.0637
Schistosoma mansoni	kinase	0.0047	0.0101	0.3894
Mycobacterium ulcerans	heat shock protein 90	0.0049	0.0109	0.5
Brugia malayi	TAR-binding protein	0.0073	0.019	0.019
Schistosoma mansoni	endoplasmin	0.0052	0.012	0.4602
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase	0.0037	0.0067	0.0138
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0093	0.0261	1
Trichomonas vaginalis	CAMK family protein kinase	0.0046	0.0097	0.2902
Trichomonas vaginalis	heat shock protein, putative	0.003	0.0043	0.0562
Treponema pallidum	heat shock protein 90	0.0049	0.0109	0.5
Trypanosoma brucei	peptidyl-prolyl cis-trans isomerase/rotamase, putative	0.0037	0.0067	0.0023
Echinococcus multilocularis	chromobox protein 1	0.0067	0.0172	0.661
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0093	0.0261	0.0261
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Loa Loa (eye worm)	endoplasmin	0.0052	0.012	0.012
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0073	0.019	0.019
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0093	0.0261	1
Giardia lamblia	Grp94/Hsp90	0.0049	0.0109	0.0909
Echinococcus granulosus	tar DNA binding protein	0.0073	0.019	0.7286
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0051	0.0115	0.4406
Brugia malayi	chromobox protein homolog 3	0.0038	0.0069	0.0069
Trichomonas vaginalis	heat shock protein, putative	0.0049	0.0109	0.3401
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0069	0.0069
Trypanosoma cruzi	polo-like protein kinase, putative	0.0093	0.0261	0.0637
Loa Loa (eye worm)	hypothetical protein	0.0057	0.0136	0.0136
Trypanosoma cruzi	heat shock protein 90, putative	0.0045	0.0093	0.0206
Trypanosoma brucei	malonyl-CoA decarboxylase, mitochondrial precursor, putative	0.1134	0.3891	1
Brugia malayi	heat shock protein 90	0.0052	0.012	0.012
Trichomonas vaginalis	heat shock protein, putative	0.0052	0.012	0.3889
Trypanosoma cruzi	heat shock protein 85, putative	0.0052	0.012	0.0274
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0041	0.0079	0.1748
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0051	0.0115	0.4406
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0057	0.0136	0.0136
Schistosoma mansoni	heat shock protein	0.0052	0.012	0.4602
Echinococcus multilocularis	heat shock protein 90	0.0045	0.0093	0.3588
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.007	0.1735
Trichomonas vaginalis	heat shock protein, putative	0.0049	0.0109	0.3401
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Schistosoma mansoni	rotamase	0.0038	0.007	0.27
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Leishmania major	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	0.0049	0.0109	0.0131
Trichomonas vaginalis	conserved hypothetical protein	0.0038	0.0069	0.1672
Plasmodium falciparum	heat shock protein 90, putative	0.0199	0.063	1
Trypanosoma brucei	polo-like protein kinase	0.0093	0.0261	0.0527
Entamoeba histolytica	peptidyl-prolyl cis-trans isomerase, putative	0.0037	0.0067	0.0429
Schistosoma mansoni	heat shock protein	0.0035	0.0059	0.2246
Plasmodium vivax	heat shock protein 86, putative	0.0052	0.012	0.1074
Schistosoma mansoni	serine/threonine protein kinase	0.0093	0.0261	1
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Trichomonas vaginalis	rotamase, putative	0.0038	0.007	0.1735
Echinococcus granulosus	chromobox protein 1	0.0067	0.0172	0.661
Brugia malayi	RNA recognition motif domain containing protein	0.0073	0.019	0.019
Loa Loa (eye worm)	hypothetical protein	0.2887	1	1
Entamoeba histolytica	heat shock protein 90, putative	0.0052	0.012	0.3038
Echinococcus granulosus	heat shock protein	0.0052	0.012	0.4602
Trichomonas vaginalis	chromobox protein, putative	0.0067	0.0172	0.6163
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0051	0.0115	0.4406
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Echinococcus granulosus	expressed protein	0.0038	0.007	0.27
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Trichomonas vaginalis	heat shock protein, putative	0.0045	0.0093	0.2741
Plasmodium vivax	heat shock protein, putative	0.0199	0.063	1
Schistosoma mansoni	chromobox protein	0.0067	0.0172	0.661
Trypanosoma cruzi	heat shock protein 85, putative	0.0052	0.012	0.0274
Plasmodium falciparum	heat shock protein 90	0.0052	0.012	0.1305
Loa Loa (eye worm)	heterochromatin protein 1	0.0067	0.0172	0.0172
Schistosoma mansoni	tar DNA-binding protein	0.0073	0.019	0.7286
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0051	0.0115	0.0115
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0093	0.0261	1
Echinococcus granulosus	heat shock protein 90	0.0045	0.0093	0.3588
Trypanosoma brucei	heat shock protein, putative	0.0052	0.012	0.016
Brugia malayi	Heterochromatin protein 1	0.0067	0.0172	0.0172
Loa Loa (eye worm)	TAR-binding protein	0.0073	0.019	0.019
Echinococcus granulosus	heat shock protein 90	0.0052	0.012	0.4602
Trypanosoma cruzi	heat shock protein 85, putative	0.0052	0.012	0.0274
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Wolbachia endosymbiont of Brugia malayi	malonyl-CoA decarboxylase	0.2887	1	1
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0052	0.012	0.1581
Brugia malayi	Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1	0.0038	0.007	0.007
Echinococcus multilocularis	heat shock protein 75 kDa, mitochondrial	0.0035	0.0059	0.2246
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Toxoplasma gondii	heat shock protein HSP90	0.0052	0.012	0.1074
Trypanosoma cruzi	heat shock protein, putative	0.0035	0.0059	0.0116
Trichomonas vaginalis	heat shock protein, putative	0.0038	0.007	0.171
Plasmodium vivax	endoplasmin, putative	0.0052	0.012	0.1074
Toxoplasma gondii	peptidylprolyl isomerase	0.0037	0.0067	0.0152
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0051	0.0115	0.4406
Mycobacterium tuberculosis	Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G)	0.0049	0.0109	0.5
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0093	0.0261	0.0527
Echinococcus multilocularis	heat shock protein 90	0.0052	0.012	0.4602
Loa Loa (eye worm)	Pin1-type peptidyl-prolyl cis-trans isomerase	0.0038	0.007	0.007
Brugia malayi	Endoplasmin precursor	0.0052	0.012	0.012
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0057	0.0136	0.0136
Brugia malayi	latrophilin 2 splice variant baaae	0.0039	0.0073	0.0073
Toxoplasma gondii	heat shock protein 90, putative	0.0052	0.012	0.1074
Trypanosoma cruzi	malonyl-CoA decarboxylase, mitochondrial precursor, putative	0.1134	0.3891	1
Leishmania major	peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative	0.0037	0.0067	0.0023
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Leishmania major	malonyl-coa decarboxylase-like protein	0.1134	0.3891	1
Toxoplasma gondii	Hsp90 domain-containing protein	0.0199	0.063	1
Trichomonas vaginalis	rotamase, putative	0.0037	0.0067	0.1599
Schistosoma mansoni	tar DNA-binding protein	0.0073	0.019	0.7286
Schistosoma mansoni	tar DNA-binding protein	0.0073	0.019	0.7286
Leishmania major	heat shock protein 83-1	0.0052	0.012	0.016
Echinococcus multilocularis	chromobox protein 1	0.0067	0.0172	0.661
Schistosoma mansoni	tar DNA-binding protein	0.0073	0.019	0.7286
Plasmodium falciparum	endoplasmin, putative	0.0038	0.007	0.045
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0073	0.0073
Trypanosoma cruzi	malonyl-CoA decarboxylase, mitochondrial precursor, putative	0.1134	0.3891	1
Loa Loa (eye worm)	heat shock protein 75	0.0035	0.0059	0.0059
Echinococcus multilocularis	heat shock protein	0.0052	0.012	0.4602
Trypanosoma brucei	heat shock protein 90, putative	0.0052	0.012	0.016
Brugia malayi	RNA binding protein	0.0073	0.019	0.019
Brugia malayi	serine/threonine-protein kinase plk-2	0.0093	0.0261	0.0261
Trichomonas vaginalis	CAMK family protein kinase	0.0093	0.0261	1
Loa Loa (eye worm)	hypothetical protein	0.003	0.004	0.004
Trypanosoma cruzi	Heat shock protein 83, putative	0.0052	0.012	0.0274
Trypanosoma cruzi	peptidyl-prolyl cis-trans isomerase	0.0037	0.0067	0.0138

Activities

Activity type	Activity value	Assay description	Source	Reference
Activity (functional)	= 15	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells. Activity expressed as no. of cells	ChEMBL.	3510299
Activity (functional)	= 15	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells.	ChEMBL.	3510299
Activity (functional)	= 17	Mutagenicity against Salmonella tester strain TA 1535 without hamster S9 mix (3 mg/plate) in cells.	ChEMBL.	3510299
Activity (functional)	= 18	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells.	ChEMBL.	3510299
Log 1/C (ADMET)	= -1.512	Concentration in nanomoles/plate to induce 50 revertants/plate.	ChEMBL.	3510299
No. of revertants per plate (functional)	= 12	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 2.5 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 13	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 25 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 13	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 1000 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 15	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 10 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 15	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 500 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 17	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 5 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 20	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 1 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 20	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 250 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 21	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 50 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 22	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 5 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 23	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 1 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 26	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 2.5 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 40	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with out hamster S9 mix (3 mg/plate) in cells at dose of 100 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 62	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 10 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 128	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 25 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 180	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 100 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 215	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 500 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 217	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 50 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 221	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 250 ug	ChEMBL.	3510299
No. of revertants per plate (functional)	= 302	compound was tested for mutagenicity against Salmonella tester strain TA 1535 with hamster S9 mix (3 mg/plate) in cells at dose of 1000 ug	ChEMBL.	3510299

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL136899
PubChem: 113506

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 236733