Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0041 | 0.4137 | 0.4137 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.007 | 0.7535 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0013 | 0.0809 | 0.0809 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0041 | 0.4137 | 0.4137 |
Schistosoma mansoni | hypothetical protein | 0.0028 | 0.2597 | 0.3446 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Brugia malayi | RNA binding protein | 0.0048 | 0.4963 | 0.4963 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0048 | 0.4963 | 0.4963 |
Echinococcus granulosus | tar DNA binding protein | 0.0048 | 0.4963 | 0.6586 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0013 | 0.0809 | 0.1074 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.007 | 0.7535 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0091 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.4137 | 0.4137 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0028 | 0.2597 | 0.2597 |
Echinococcus multilocularis | tar DNA binding protein | 0.0048 | 0.4963 | 0.6586 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.2597 | 0.2597 |
Loa Loa (eye worm) | RNA binding protein | 0.0048 | 0.4963 | 0.4963 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0041 | 0.4137 | 0.4137 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0091 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.007 | 0.7535 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.007 | 0.7535 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.007 | 0.7535 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0048 | 0.4963 | 0.4963 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.007 | 0.7535 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0013 | 0.0809 | 0.1074 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0013 | 0.0809 | 0.0809 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0809 | 0.0809 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.0809 | 0.1074 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.007 | 0.7535 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.007 | 0.7535 | 0.7535 |
Echinococcus multilocularis | GPCR, family 2 | 0.0013 | 0.0809 | 0.1074 |
Schistosoma mansoni | tar DNA-binding protein | 0.0048 | 0.4963 | 0.6586 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | TAR-binding protein | 0.0048 | 0.4963 | 0.4963 |
Brugia malayi | TAR-binding protein | 0.0048 | 0.4963 | 0.4963 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0013 | 0.0809 | 0.0809 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0013 | 0.0809 | 0.1074 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.007 | 0.7535 | 0.7535 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Relative potency (ADMET) | < 0.05 | Binding affinity against digitalis receptor was determined relative to digitoxigenin, | ChEMBL. | 7143360 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.