Detailed information for compound 24194

Basic information

Technical information
  • TDR Targets ID: 24194
  • Name: (3-bromophenyl)boronic acid
  • MW: 200.826 | Formula: C6H6BBrO2
  • H donors: 2 H acceptors: 2 LogP: 1.52 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Brc1cccc(c1)B(O)O
  • InChi: 1S/C6H6BBrO2/c8-6-3-1-2-5(4-6)7(9)10/h1-4,9-10H
  • InChiKey: AFSSVCNPDKKSRR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 89598-96-9
  • 3-Bromophenylboronic acid
  • B1920G1
  • 441627_ALDRICH
  • ST5405956

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum proteasome subunit alpha type-1, putative 0.0042 0.0017 0.0003
Echinococcus multilocularis proteasome (prosome, macropain) 0.0238 0.0793 0.2311
Plasmodium falciparum serine repeat antigen 4 0.0059 0.0082 0.0376
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0054 0.0062 0.0411
Giardia lamblia Cathepsin B precursor 0.026 0.0879 1
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0042 0.0017 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0354 0.3033
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0121 0.0327 0.0864
Trypanosoma cruzi cysteine proteinase, putative 0.0128 0.0354 0.1281
Toxoplasma gondii hypothetical protein 0.0097 0.0235 0.1251
Trichomonas vaginalis calcineurin B subunit, putative 0.0046 0.0032 0.0183
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0202 0.0339
Loa Loa (eye worm) hypothetical protein 0.0071 0.0131 0.0131
Echinococcus granulosus neuronal calcium sensor 0.0046 0.003 0.0089
Schistosoma mansoni neprilysin-2 (M13 family) 0.014 0.0403 0.0677
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0059 0.0082 0.0376
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0059 0.0082 0.0463
Schistosoma mansoni chromatin regulatory protein sir2 0.0127 0.035 0.0589
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0042 0.0017 0.0028
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 0.4222
Onchocerca volvulus Chorion peroxidase homolog 0.035 0.1235 0.6249
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0059 0.0082 0.0376
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0277 0.0945 0.2882
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0131 0.0654
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0059 0.0084 0.0387
Echinococcus granulosus sarcoplasmic calcium binding protein 0.0046 0.003 0.0089
Leishmania major kinesin, putative 0.0227 0.0746 0.6546
Loa Loa (eye worm) hypothetical protein 0.0107 0.0275 0.0275
Echinococcus granulosus enteropeptidase 0.0121 0.0329 0.0959
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0042 0.0017 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0322 0.1122 0.4187
Echinococcus granulosus cathepsin L 0.0059 0.0082 0.0239
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0042 0.0017 0.0017
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0042 0.0017 0.0002
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0042 0.0017 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0354 0.2004
Echinococcus multilocularis 20S proteasome subunit alpha 6 0.0042 0.0017 0.0048
Schistosoma mansoni hypothetical protein 0.0046 0.003 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Trypanosoma brucei calpain-like protein, putative 0.0324 0.1132 1
Loa Loa (eye worm) hypothetical protein 0.0209 0.0679 0.0679
Echinococcus multilocularis programmed cell death protein 0.0046 0.003 0.0089
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Brugia malayi Animal haem peroxidase family protein 0.035 0.1235 0.1235
Brugia malayi Pepsin A precursor 0.0157 0.047 0.047
Echinococcus granulosus tumor protein p63 0.0668 0.2492 0.7266
Trypanosoma brucei proteasome beta 3 subunit, putative 0.0042 0.0017 0.0005
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0002
Schistosoma mansoni endothelin-converting enzyme-related 0.0067 0.0117 0.0196
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0046 0.003 0.0082
Entamoeba histolytica proteasome subunit beta type 7-B precursor, putative 0.0042 0.0017 0.0209
Trypanosoma cruzi centrin-3 0.0046 0.003 0.0055
Mycobacterium ulcerans lipase LipD 0.0071 0.0131 0.0258
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0277 0.0945 0.1589
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Trypanosoma brucei cysteine peptidase C (CPC) 0.026 0.0879 0.7733
Leishmania major proteasome beta 5 subunit, putative 0.0238 0.0793 0.6961
Schistosoma mansoni Mername-AA248 (C02 family) 0.0324 0.1132 0.1903
Giardia lamblia Cysteine protease 0.0059 0.0082 0.0763
Toxoplasma gondii peptidase, T1 family protein 0.0042 0.0017 0.0003
Plasmodium falciparum importin beta, putative 0.0057 0.0076 0.034
Brugia malayi RNA, U transporter 1 0.0162 0.0491 0.0491
Leishmania major proteasome alpha 3 subunit, putative 0.0042 0.0017 0.0005
Schistosoma mansoni survival motor neuron protein 0.0094 0.0221 0.0372
Echinococcus granulosus cathepsin b 0.071 0.2658 0.775
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Leishmania major calcineurin B subunit, putative 0.0046 0.003 0.0129
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0051 0.0051
Trypanosoma brucei centrin, putative 0.0046 0.003 0.0129
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0059 0.0082 0.0138
Echinococcus multilocularis calmodulin 0.0046 0.003 0.0089
Loa Loa (eye worm) calpain 0.0324 0.1132 0.1132
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0042 0.0016 0.0016
Onchocerca volvulus 0.0229 0.0754 0.3784
Plasmodium vivax proteasome subunit alpha type-2, putative 0.0042 0.0017 0.0003
Leishmania major hs1vu complex proteolytic subunit-like,hs1vu complex proteolytic subunit-like, threonine peptidase, Clan T(1), family T1B 0.0042 0.0017 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.016 0.0482 0.2723
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0059 0.0082 0.0376
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Onchocerca volvulus 0.035 0.1235 0.6249
Echinococcus multilocularis proteasome subunit alpha type 2 0.0042 0.0017 0.0048
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0127 0.035 0.1266
Brugia malayi beta-lactamase family protein 0.0071 0.0131 0.0131
Plasmodium falciparum proteasome subunit beta type-1, putative 0.0135 0.0383 0.2092
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0131 0.0434
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0121 0.0329 0.0553
Echinococcus granulosus calpain 0.0324 0.1132 0.3299
Mycobacterium leprae probable zinc metalloprotease 0.0277 0.0945 0.2882
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0059 0.0082 0.0463
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0042 0.0017 0.0209
Echinococcus granulosus transmembrane protease serine 3 0.0121 0.0329 0.0959
Brugia malayi beta-lactamase 0.0071 0.0131 0.0131
Toxoplasma gondii proteasome subunit alpha1, putative 0.0042 0.0017 0.0003
Brugia malayi proteasome subunit alpha type 6 0.0042 0.0017 0.0017
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0354 0.0354
Leishmania major programmed cell death 6 protein-like protein 0.0046 0.003 0.0129
Echinococcus multilocularis calpain family protein 1, d 0.0632 0.2351 0.6855
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Schistosoma mansoni calpain (C02 family) 0.0324 0.1132 0.1903
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0404 0.2283
Brugia malayi MH2 domain containing protein 0.0117 0.0314 0.0314
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0905 0.3428 0.5763
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0042 0.0017 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0123 0.0403
Giardia lamblia 20S proteasome alpha subunit 1 0.0042 0.0017 0.0006
Echinococcus granulosus EF HAND 1 calcium binding site 0.0046 0.003 0.0089
Plasmodium vivax proteasome subunit beta type-4, putative 0.0042 0.0017 0.0003
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Onchocerca volvulus 0.0121 0.0329 0.1603
Giardia lamblia 20S proteasome alpha subunit 4 0.0042 0.0017 0.0006
Trypanosoma cruzi oligopeptidase b 0.0054 0.0062 0.0173
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Schistosoma mansoni rab 0.0046 0.003 0.0051
Brugia malayi beta-lactamase family protein 0.0071 0.0131 0.0131
Plasmodium falciparum plasmepsin II 0.0485 0.1768 1
Brugia malayi Papain family cysteine protease containing protein 0.0059 0.0082 0.0082
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Trichomonas vaginalis DNA-dependent protein kinase catalytic subunit-interacting protein, putative 0.0046 0.003 0.0172
Brugia malayi calpain D 0.0097 0.0235 0.0235
Toxoplasma gondii troponin c, isotype gamma, putative 0.0046 0.003 0.0082
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0229 0.0754 0.0754
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Echinococcus multilocularis glycoprotein Antigen 5 0.0121 0.0329 0.0959
Trypanosoma brucei cytochrome P450, putative 0.0051 0.0051 0.0316
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Giardia lamblia 20S proteasome alpha subunit 6 0.0042 0.0017 0.0006
Echinococcus granulosus prolyl endopeptidase 0.0135 0.0383 0.1116
Mycobacterium tuberculosis Conserved protein 0.0071 0.0131 0.0225
Trypanosoma cruzi calmodulin, putative 0.0046 0.003 0.0055
Toxoplasma gondii centrin 0.0046 0.003 0.0082
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0042 0.0017 0.0209
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0085 0.0247
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Leishmania major calpain-like protein, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Plasmodium vivax plasmepsin IV, putative 0.0485 0.1768 1
Brugia malayi Proteasome A-type and B-type family protein 0.0042 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0098 0.0237 0.0237
Brugia malayi proteasome subunit beta type 1 0.0135 0.0383 0.0383
Trypanosoma brucei hypothetical protein, conserved 0.0046 0.003 0.0129
Trypanosoma cruzi I/6 autoantigen, putative 0.0046 0.003 0.0055
Echinococcus multilocularis neurocalcin 0.0046 0.003 0.0089
Loa Loa (eye worm) hypothetical protein 0.0277 0.0945 0.0945
Brugia malayi cathepsin Z-like cysteine proteinase 0.0059 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0097 0.0235 0.133
Giardia lamblia NAD-dependent histone deacetylase Sir2 0.014 0.0404 0.4495
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0059 0.0082 0.0763
Echinococcus granulosus cathepsin l cysteine peptidase 0.0229 0.0754 0.2199
Trypanosoma cruzi cytochrome P450, putative 0.0051 0.0051 0.0134
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0042 0.0017 0.0048
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0017 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Plasmodium falciparum serine repeat antigen 2 0.0059 0.0082 0.0376
Echinococcus multilocularis EF hand domain containing family member A2 0.0046 0.0032 0.0094
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0059 0.0082 0.0138
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0085 0.0143
Brugia malayi Cathepsin L-like precursor 0.0229 0.0754 0.0754
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0042 0.0017 0.0209
Trypanosoma cruzi cysteine peptidase, putative 0.0128 0.0354 0.1281
Trichomonas vaginalis conserved hypothetical protein 0.0097 0.0235 0.133
Brugia malayi Cathepsin L-like precursor 0.0229 0.0754 0.0754
Onchocerca volvulus 0.0059 0.0082 0.0335
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0088 0.0196 0.033
Onchocerca volvulus 0.0229 0.0754 0.3784
Toxoplasma gondii cathepsin CPL 0.0229 0.0754 0.4212
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0059 0.0082 0.0082
Trichomonas vaginalis centrin, putative 0.0046 0.003 0.0172
Leishmania major centrin, putative 0.0046 0.003 0.0129
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.003
Brugia malayi Proteasome A-type and B-type family protein 0.0042 0.0017 0.0017
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0324 0.1132 0.4222
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Echinococcus multilocularis Proteasome, subunit alpha beta 0.0042 0.0017 0.0048
Echinococcus granulosus calumenin 0.0046 0.0032 0.0094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0059 0.0082 0.0138
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0059 0.0082 0.0463
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0042 0.0017 0.0005
Entamoeba histolytica cysteine protease, putative 0.0059 0.0082 0.1033
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0042 0.0017 0.0005
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0097 0.0235 0.083
Echinococcus multilocularis proteasome subunit alpha type 6 0.0042 0.0017 0.0048
Brugia malayi cathepsin F-like cysteine proteinase 0.0069 0.0123 0.0123
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0229 0.0754 0.4212
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0082
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0135 0.0383 0.3287
Leishmania major hypothetical protein, conserved 0.0097 0.0235 0.1965
Plasmodium falciparum proteasome subunit alpha type-7, putative 0.0042 0.0017 0.0003
Loa Loa (eye worm) hypothetical protein 0.0209 0.0679 0.0679
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0202 0.0339
Echinococcus granulosus snurportin 1 0.0609 0.2258 0.6584
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0905 0.3428 0.5763
Giardia lamblia Proteasome subunit beta type 2 0.0088 0.0196 0.2089
Brugia malayi proteasome subunit alpha type 3 0.0042 0.0017 0.0017
Brugia malayi Ets-domain containing protein 0.0143 0.0417 0.0417
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0485 0.1768 0.2974
Plasmodium falciparum proteasome subunit beta type-3, putative 0.0042 0.0017 0.0003
Trichomonas vaginalis calcium binding protein, putative 0.0046 0.003 0.0172
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0229 0.0754 0.2199
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0097 0.0235 0.133
Onchocerca volvulus 0.0098 0.0237 0.113
Loa Loa (eye worm) beta-lactamase 0.0071 0.0131 0.0131
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Entamoeba histolytica proteasome subunit alpha type 2-A, putative 0.0042 0.0017 0.0209
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0131 0.0739
Plasmodium falciparum calpain 0.0097 0.0235 0.1251
Mycobacterium tuberculosis Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. 0.0238 0.0793 0.2384
Plasmodium falciparum centrin-1 0.0046 0.003 0.0082
Schistosoma mansoni neprilysin 0.0072 0.0136 0.0228
Echinococcus multilocularis calpain 5 0.0324 0.1132 0.3299
Trypanosoma brucei Calpain-like protein 2 0.0097 0.0235 0.1965
Onchocerca volvulus 0.0157 0.047 0.2326
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Loa Loa (eye worm) cathepsin B 0.026 0.0879 0.0879
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.071 0.2658 0.4469
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0085 0.0109
Giardia lamblia Cysteine protease 0.0059 0.0082 0.0763
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0059 0.0082 0.0138
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0059 0.0082 0.0763
Loa Loa (eye worm) calmodulin-like protein 0.0046 0.003 0.003
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0042 0.0017 0.0209
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Loa Loa (eye worm) EF hand family protein 0.0046 0.003 0.003
Brugia malayi Importin beta-1 subunit 0.0057 0.0076 0.0076
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0076 0.0534
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Trichomonas vaginalis calmodulin-2, putative 0.0046 0.003 0.0172
Toxoplasma gondii EFHC1, putative 0.0046 0.003 0.0082
Trypanosoma brucei proteasome beta 2 subunit, putative 0.0042 0.0017 0.0005
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Brugia malayi calpain 7 0.0324 0.1132 0.1132
Trypanosoma cruzi programmed cell death 6 protein-like, putative 0.0046 0.003 0.0055
Leishmania major protein kinase, putative 0.0046 0.003 0.0129
Schistosoma mansoni centrin 0.0046 0.003 0.0051
Loa Loa (eye worm) trypsin family protein 0.0121 0.0329 0.0329
Trypanosoma brucei proteasome alpha 1 subunit, putative 0.0042 0.0017 0.0005
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0033 0.0186
Trichomonas vaginalis calcium binding proteins, putative 0.0046 0.003 0.0172
Trichomonas vaginalis importin beta-1, putative 0.0046 0.0033 0.0186
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0059 0.0082 0.0463
Schistosoma mansoni memapsin-2 (A01 family) 0.0565 0.2086 0.3507
Loa Loa (eye worm) hypothetical protein 0.0229 0.0754 0.0754
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0082
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0046 0.003 0.0384
Echinococcus granulosus 20S proteasome subunit alpha 6 0.0042 0.0017 0.0048
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Echinococcus granulosus importin subunit beta 1 0.0057 0.0076 0.022
Loa Loa (eye worm) CYP4Cod1 0.0051 0.0051 0.0051
Leishmania major cathepsin L-like protease 0.0229 0.0754 0.6617
Giardia lamblia Cathepsin L precursor 0.0059 0.0082 0.0763
Echinococcus multilocularis snurportin 1 0.0609 0.2258 0.6584
Brugia malayi Blistered cuticle protein 3 0.035 0.1235 0.1235
Toxoplasma gondii calmodulin CAM1 0.0046 0.0032 0.0093
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0128 0.0354 0.0596
Trypanosoma brucei proteasome beta-1 subunit, putative 0.0042 0.0017 0.0005
Mycobacterium ulcerans zinc metalloprotease 0.0277 0.0945 0.2906
Loa Loa (eye worm) peptidase family M13 containing protein 0.0205 0.0659 0.0659
Echinococcus multilocularis chromatin regulatory protein sir2 0.0127 0.035 0.1022
Brugia malayi Cathepsin L-like precursor 0.016 0.0482 0.0482
Schistosoma mansoni ran 0.0042 0.0016 0.0027
Trypanosoma brucei calpain-like protein, putative 0.0324 0.1132 1
Echinococcus multilocularis calpain A 0.0905 0.3429 1
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0237 0.0398
Schistosoma mansoni hypothetical protein 0.0072 0.0136 0.0228
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0059 0.0082 0.0463
Entamoeba histolytica cysteine protease, putative 0.0059 0.0082 0.1033
Echinococcus granulosus Proteasome subunit alpha beta 0.0042 0.0017 0.0048
Brugia malayi aspartic protease BmAsp-1, identical 0.0157 0.047 0.047
Brugia malayi Papain family cysteine protease containing protein 0.0229 0.0754 0.0754
Plasmodium vivax aspartyl proteinase, putative 0.0157 0.047 0.259
Loa Loa (eye worm) calpain 5 0.0227 0.0746 0.0746
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0085 0.0392
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0097 0.0235 0.083
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0127 0.035 0.1982
Giardia lamblia 20S proteasome alpha subunit 7 0.0042 0.0017 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0131 0.0739
Entamoeba histolytica calcium-binding protein, putative 0.0046 0.003 0.0384
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 0.4222
Plasmodium vivax vivapain-3 0.0128 0.0354 0.1931
Echinococcus multilocularis EF HAND 1, calcium binding site 0.0046 0.003 0.0089
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Onchocerca volvulus 0.035 0.1235 0.6249
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0097 0.0235 0.133
Trypanosoma brucei proteasome alpha 7 subunit 0.0042 0.0017 0.0005
Brugia malayi hypothetical protein 0.0121 0.0329 0.0329
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0097 0.0235 0.083
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0059 0.0082 0.0763
Trypanosoma cruzi cytochrome P450, putative 0.0051 0.0051 0.0134
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0082 0.0463
Entamoeba histolytica proteasome subunit alpha type 7, putative 0.0042 0.0017 0.0209
Leishmania major cathepsin L-like protease 0.0229 0.0754 0.6617
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0485 0.1768 1
Plasmodium vivax proteasome subunit alpha type-7, putative 0.0042 0.0017 0.0003
Trypanosoma cruzi proteasome alpha 2 subunit, putative 0.0042 0.0017 0.0002
Brugia malayi EF hand family protein 0.0046 0.0032 0.0032
Schistosoma mansoni chromatin regulatory protein sir2 0.014 0.0404 0.0679
Loa Loa (eye worm) transcriptional regulator 0.0127 0.035 0.035
Loa Loa (eye worm) hypothetical protein 0.0209 0.0679 0.0679
Toxoplasma gondii cathepsin CPC2 0.0059 0.0082 0.0376
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0082
Schistosoma mansoni cathepsin F (C01 family) 0.0229 0.0754 0.1268
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0042 0.0017 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0082 0.0463
Echinococcus granulosus programmed cell death protein 0.0046 0.003 0.0089
Brugia malayi programmed cell death protein 6 0.0046 0.003 0.003
Brugia malayi Proteasome A-type and B-type family protein 0.0238 0.0793 0.0793
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Plasmodium vivax plasmepsin V, putative 0.0274 0.0933 0.5234
Trypanosoma brucei CAMK/CAMKL family protein kinase, putative 0.0046 0.003 0.0129
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0135 0.0383 0.1116
Echinococcus granulosus cathepsin l1 0.0229 0.0754 0.2199
Leishmania major proteasome beta 2 subunit, putative 0.0088 0.0196 0.1616
Giardia lamblia Hypothetical protein 0.0059 0.0082 0.0763
Giardia lamblia Cysteine protease 0.0059 0.0082 0.0763
Brugia malayi Trypsin family protein 0.0121 0.0329 0.0329
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Echinococcus multilocularis cathepsin b 0.071 0.2658 0.775
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0017 0.0094
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0059 0.0082 0.0138
Toxoplasma gondii aspartyl protease ASP3 0.0344 0.1212 0.6822
Plasmodium falciparum plasmepsin VII 0.0157 0.047 0.259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Giardia lamblia 20S proteasome alpha subunit 2 0.0042 0.0017 0.0006
Onchocerca volvulus Cathepsin L homolog 0.0229 0.0754 0.3784
Plasmodium falciparum plasmepsin V 0.0274 0.0933 0.5234
Brugia malayi Pre-SET motif family protein 0.0059 0.0084 0.0084
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0277 0.0945 0.0945
Toxoplasma gondii proteasome subunit beta type 7 precursor, putative 0.0042 0.0017 0.0003
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0059 0.0082 0.0082
Plasmodium falciparum plasmepsin X 0.0344 0.1212 0.6822
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Leishmania major proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative 0.0135 0.0383 0.3287
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Echinococcus multilocularis subfamily T1A non peptidase ue 0.0042 0.0017 0.0048
Trypanosoma brucei I/6 autoantigen 0.0046 0.003 0.0129
Leishmania major cathepsin L-like protease 0.0229 0.0754 0.6617
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.014 0.0403 0.0677
Plasmodium vivax proteasome subunit beta type-6, putative 0.0042 0.0017 0.0003
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Onchocerca volvulus 0.035 0.1235 0.6249
Giardia lamblia Cathepsin L precursor 0.0059 0.0082 0.0763
Echinococcus multilocularis proteasome subunit beta type 7 0.0042 0.0017 0.0048
Schistosoma mansoni peroxidasin 0.035 0.1235 0.2076
Trypanosoma cruzi I/6 autoantigen, putative 0.0046 0.003 0.0055
Brugia malayi Peroxidasin 0.035 0.1235 0.1235
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0229 0.0754 0.0754
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0082
Trypanosoma cruzi importin beta-1 subunit, putative 0.0046 0.0033 0.0064
Trypanosoma brucei importin beta-1 subunit, putative 0.0057 0.0076 0.0534
Trypanosoma brucei cysteine peptidase, putative 0.0097 0.0235 0.1965
Schistosoma mansoni cathepsin D (A01 family) 0.1542 0.5947 1
Plasmodium falciparum plasmepsin III 0.0157 0.047 0.259
Plasmodium vivax hypothetical protein, conserved 0.0046 0.0032 0.0093
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0059 0.0082 0.0138
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0135 0.0383 0.1116
Trichomonas vaginalis calpain, putative 0.0097 0.0235 0.133
Schistosoma mansoni proteasome subunit beta 1 (T01 family) 0.0135 0.0383 0.0643
Echinococcus granulosus centrin 2 0.0046 0.003 0.0089
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0314 0.0314
Loa Loa (eye worm) hypothetical protein 0.0046 0.003 0.003
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0059 0.0082 0.0376
Schistosoma mansoni proteasome catalytic subunit 1 (T01 family) 0.0042 0.0017 0.0028
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0059 0.0082 0.0138
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0131 0.0739
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Brugia malayi cathepsin B-like cysteine proteinase 0.071 0.2658 0.2658
Echinococcus multilocularis calbindin 32 0.0046 0.0032 0.0094
Plasmodium falciparum serine repeat antigen 1 0.0059 0.0082 0.0376
Entamoeba histolytica probable proteasome subunit beta type 2, putative 0.0088 0.0196 0.2477
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0128 0.0354 0.2004
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0069 0.0123 0.0123
Toxoplasma gondii proteasome subunit beta type 2, putative 0.0088 0.0196 0.1028
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0059 0.0084 0.0141
Echinococcus granulosus proteasome prosome macropain subunit beta type 0.0042 0.0017 0.0048
Trichomonas vaginalis calcineurin B subunit, putative 0.0046 0.003 0.0172
Plasmodium vivax serine-repeat antigen (SERA) 0.0059 0.0082 0.0376
Plasmodium falciparum proteasome subunit beta type-7, putative 0.0042 0.0017 0.0003
Trypanosoma cruzi oligopeptidase b 0.0054 0.0062 0.0173
Onchocerca volvulus 0.0469 0.1706 0.8667
Trypanosoma cruzi mitochondrial calcium uptake 1, putative 0.0046 0.003 0.0055
Entamoeba histolytica grainin, putative 0.0046 0.0032 0.0408
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0054 0.0062 0.0034
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Leishmania major proteasome alpha 1 subunit, putative 0.0042 0.0017 0.0005
Plasmodium falciparum proteasome subunit beta type-5 0.0238 0.0793 0.4431
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Loa Loa (eye worm) proteasome subunit alpha type 1 0.0042 0.0017 0.0017
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Leishmania major cysteine peptidase A (CPA) 0.0229 0.0754 0.6617
Trypanosoma cruzi cysteine proteinase, putative 0.0128 0.0354 0.1281
Brugia malayi cathepsin Z-like cysteine proteinase 0.0059 0.0082 0.0082
Echinococcus granulosus glycoprotein Antigen 5 0.0121 0.0329 0.0959
Trypanosoma cruzi kinesin, putative 0.0227 0.0746 0.2764
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Schistosoma mansoni proteasome subunit alpha 7 (T01 family) 0.0042 0.0017 0.0028
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0042 0.0017 0.0002
Trypanosoma cruzi centrin, putative 0.0046 0.003 0.0055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0128 0.0354 0.0596
Toxoplasma gondii proteasome beta subunit 0.0042 0.0017 0.0003
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0404 0.2283
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0057 0.0075 0.0219
Loa Loa (eye worm) animal heme peroxidase 0.035 0.1235 0.1235
Loa Loa (eye worm) hypothetical protein 0.0071 0.0131 0.0131
Entamoeba histolytica cysteine protease, putative 0.0059 0.0082 0.1033
Plasmodium vivax proteasome subunit beta type-7, putative 0.0042 0.0017 0.0003
Leishmania major proteasome alpha 2 subunit, putative 0.0042 0.0017 0.0005
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0354 0.4472
Echinococcus granulosus proteasome subunit alpha type 6 0.0042 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0135 0.0383 0.0383
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 1
Trichomonas vaginalis calpain, putative 0.0097 0.0235 0.133
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Echinococcus granulosus proteasome prosome macropain 0.0238 0.0793 0.2311
Entamoeba histolytica cysteine protease, putative 0.0059 0.0082 0.1033
Loa Loa (eye worm) hypothetical protein 0.0535 0.1966 0.1966
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0046 0.003 0.0055
Plasmodium falciparum cysteine proteinase falcipain 3 0.0229 0.0754 0.4212
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Trypanosoma brucei calmodulin, putative 0.0046 0.003 0.0129
Mycobacterium tuberculosis Conserved protein 0.0071 0.0131 0.0225
Trypanosoma brucei Proteasome subunit A N-terminal signature/Proteasome subunit, putative 0.0042 0.0017 0.0005
Giardia lamblia Cathepsin B precursor 0.0059 0.0082 0.0763
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.071 0.2658 0.4469
Schistosoma mansoni calmodulin 0.0046 0.003 0.0051
Brugia malayi hypothetical protein 0.035 0.1235 0.1235
Giardia lamblia Proteasome subunit beta type 7 precursor 0.0042 0.0017 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Schistosoma mansoni neuronal calcium sensor 0.0046 0.003 0.0051
Brugia malayi Eukaryotic aspartyl protease family protein 0.0157 0.047 0.047
Schistosoma mansoni peroxidasin 0.035 0.1235 0.2076
Plasmodium vivax proteasome subunit alpha type-3, putative 0.0042 0.0017 0.0003
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0042 0.0017 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Trypanosoma brucei antigen, putative 0.0324 0.1132 1
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0088 0.0196 0.111
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0905 0.3428 0.9994
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Toxoplasma gondii 20S proteasome subunit beta 7, putative 0.0042 0.0017 0.0003
Schistosoma mansoni ran 0.0042 0.0016 0.0027
Plasmodium vivax unspecified product 0.0059 0.0082 0.0376
Entamoeba histolytica cysteine proteinase 1, putative 0.0128 0.0354 0.4472
Plasmodium falciparum cysteine proteinase falcipain 1 0.0128 0.0354 0.1931
Leishmania major hypothetical protein, conserved 0.0046 0.003 0.0129
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Giardia lamblia Proteasome subunit beta type 5 precursor 0.0238 0.0793 0.9002
Schistosoma mansoni Sarcoplasmic calcium-binding protein (SCP). 0.0046 0.003 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0082 0.0463
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Schistosoma mansoni proteasome subunit alpha 4 (T01 family) 0.0042 0.0017 0.0028
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Trypanosoma brucei calpain, putative 0.0097 0.0235 0.1965
Trypanosoma cruzi proteasome beta 2 subunit, putative 0.0042 0.0017 0.0002
Brugia malayi Cathepsin L-like cysteine proteinase 0.016 0.0482 0.0482
Schistosoma mansoni proteasome subunit alpha 2 (T01 family) 0.0042 0.0017 0.0028
Schistosoma mansoni cathepsin S (C01 family) 0.0059 0.0082 0.0138
Echinococcus granulosus proteasome subunit beta type 6 0.0042 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0277 0.0945 0.0945
Leishmania major oligopeptidase b 0.0054 0.0062 0.0411
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0097 0.0235 0.083
Leishmania major cytochrome p450-like protein 0.0051 0.0051 0.0316
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0017 0.0094
Echinococcus multilocularis tumor protein p63 0.0668 0.2492 0.7266
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Schistosoma mansoni gabp alpha 0.0143 0.0417 0.0701
Entamoeba histolytica proteasome subunit alpha type 5, putative 0.0042 0.0017 0.0209
Loa Loa (eye worm) hypothetical protein 0.0205 0.0659 0.0659
Trypanosoma brucei proteasome beta 6 subunit 0.0135 0.0383 0.3287
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0123 0.0403
Trichomonas vaginalis calcium binding protein, putative 0.0046 0.003 0.0172
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0127 0.035 0.1982
Onchocerca volvulus 0.0157 0.047 0.2326
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0131 0.0381
Echinococcus granulosus EF hand domain containing family member A2 0.0046 0.003 0.0089
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0042 0.0017 0.0028
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0485 0.1768 0.5157
Trypanosoma brucei Component of motile flagella 41 0.0046 0.003 0.0129
Echinococcus granulosus chromatin regulatory protein sir2 0.0127 0.035 0.1022
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0059 0.0082 0.0138
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0404 0.2283
Entamoeba histolytica cysteine proteinase, putative 0.0229 0.0754 0.9516
Trypanosoma brucei calpain-like protein, putative 0.0324 0.1132 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0042 0.0016 0.0016
Plasmodium falciparum plasmepsin IX 0.0344 0.1212 0.6822
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.026 0.0879 0.4968
Mycobacterium ulcerans hypothetical protein 0.0121 0.0329 0.0903
Echinococcus granulosus proteasome prosome macropain subunit beta 0.0088 0.0196 0.0572
Schistosoma mansoni calcium binding atopy-related autoantigen 0.0046 0.0032 0.0054
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Entamoeba histolytica calcium binding family protein 0.0046 0.003 0.0384
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0859 0.3247 0.546
Trypanosoma brucei Calpain-like protein 1.1 0.0097 0.0235 0.1965
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0042 0.0017 0.0002
Brugia malayi Fli-1 protein 0.0435 0.1572 0.1572
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0094 0.0221 0.0221
Entamoeba histolytica cysteine protease, putative 0.0229 0.0754 0.9516
Leishmania major centrin, putative 0.0046 0.003 0.0129
Trypanosoma brucei caltractin, putative 0.0046 0.003 0.0129
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0097 0.0235 0.133
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Mycobacterium ulcerans proteasome PrcA 0.0829 0.3127 1
Trypanosoma cruzi calmodulin, putative 0.0046 0.003 0.0055
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Trypanosoma brucei Present in the outer mitochondrial membrane proteome 33 0.0046 0.003 0.0129
Loa Loa (eye worm) animal heme peroxidase 0.035 0.1235 0.1235
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0059 0.0082 0.0376
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0131 0.0258
Trichomonas vaginalis Crustacean calcium-binding protein, putative 0.0046 0.003 0.0172
Toxoplasma gondii ABC1 family protein 0.0071 0.0131 0.0654
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.0482
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.003 0.0172
Onchocerca volvulus 0.0121 0.0329 0.1603
Brugia malayi hypothetical protein 0.0149 0.0441 0.0441
Leishmania major hypothetical protein, unknown function 0.0097 0.0235 0.1965
Leishmania major calmodulin, putative 0.0046 0.003 0.0129
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0131 0.022
Mycobacterium ulcerans hypothetical protein 0.0071 0.0131 0.0258
Onchocerca volvulus Peroxidasin homolog 0.035 0.1235 0.6249
Entamoeba histolytica proteasome subunit alpha type 1, putative 0.0042 0.0017 0.0209
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0324 0.1132 1
Toxoplasma gondii aspartyl protease ASP1 0.0485 0.1768 1
Schistosoma mansoni hypothetical protein 0.0072 0.0136 0.0228
Plasmodium falciparum proteasome subunit beta type-6, putative 0.0042 0.0017 0.0003
Echinococcus multilocularis centrin 2 0.0046 0.003 0.0089
Echinococcus granulosus EF hand domain containing family member A2 0.0046 0.0032 0.0094
Schistosoma mansoni centrin-related 0.0046 0.003 0.0051
Schistosoma mansoni cathepsin B (C01 family) 0.0059 0.0082 0.0138
Echinococcus multilocularis Mastin 0.0121 0.0329 0.0959
Echinococcus granulosus neurocalcin 0.0046 0.003 0.0089
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0042 0.0017 0.0094
Leishmania major proteasome beta-1 subunit, putative 0.0042 0.0017 0.0005
Trypanosoma brucei prolyl endopeptidase 0.0135 0.0383 0.3287
Toxoplasma gondii proteasome subunit alpha type, putative 0.0042 0.0017 0.0003
Echinococcus multilocularis GA binding protein alpha chain 0.0143 0.0417 0.1216
Echinococcus multilocularis survival motor neuron protein 1 0.046 0.167 0.4868
Plasmodium vivax proteasome subunit alpha type-1, putative 0.0042 0.0017 0.0003
Schistosoma mansoni mitochondrial solute carrier 0.0046 0.003 0.0051
Brugia malayi proteasome subunit alpha type 4 0.0042 0.0017 0.0017
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0059 0.0082 0.0376
Echinococcus multilocularis proteasome subunit beta type 6 0.0042 0.0017 0.0048
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0059 0.0082 0.0082
Trypanosoma brucei calmodulin, putative 0.0046 0.0032 0.0146
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Loa Loa (eye worm) hypothetical protein 0.0069 0.0123 0.0123
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0127 0.035 0.2998
Giardia lamblia Cathepsin L-like protease 0.0059 0.0082 0.0763
Giardia lamblia Cathepsin L precursor 0.0059 0.0082 0.0763
Echinococcus multilocularis proteasome subunit beta (t family) proteasome (prosome macropain) subunit beta 0.0042 0.0017 0.0048
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Mycobacterium leprae Probable lipase LipE 0.0071 0.0131 0.0225
Onchocerca volvulus 0.0071 0.0131 0.0586
Onchocerca volvulus 0.0121 0.0329 0.1603
Giardia lamblia Cathepsin B precursor 0.0059 0.0082 0.0763
Schistosoma mansoni proteasome subunit alpha 3 (T01 family) 0.0042 0.0017 0.0028
Echinococcus multilocularis prolyl endopeptidase 0.0135 0.0383 0.1116
Entamoeba histolytica hypothetical protein 0.0059 0.0082 0.1033
Leishmania major calpain family cysteine protease-like protein 0.0097 0.0235 0.1965
Plasmodium vivax proteasome subunit beta type-1, putative 0.0135 0.0383 0.2092
Echinococcus multilocularis cathepsin L 0.0059 0.0082 0.0239
Brugia malayi fibroinase precursor 0.0059 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0059 0.0082 0.0463
Leishmania major proteasome alpha 1 subunit, putative 0.0042 0.0017 0.0005
Giardia lamblia Proteasome subunit beta type 3 0.0042 0.0017 0.0006
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0085 0.0247
Trypanosoma cruzi proteasome subunit alpha type-5, putative 0.0042 0.0017 0.0002
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.071 0.2658 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0131 0.0739
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Leishmania major centrin, putative,caltractin, putative 0.0046 0.003 0.0129
Plasmodium vivax proteasome subunit beta type-5, putative 0.0238 0.0793 0.4431
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Giardia lamblia 20S proteasome alpha subunit 3 0.0042 0.0017 0.0006
Echinococcus multilocularis neuronal calcium sensor 0.0046 0.003 0.0089
Entamoeba histolytica cysteine proteinase 2 0.0128 0.0354 0.4472
Plasmodium falciparum ATP-dependent protease subunit ClpQ 0.0042 0.0017 0.0003
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0135 0.0383 0.0643
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0314 0.0314
Toxoplasma gondii proteasome subunit 0.0042 0.0017 0.0003
Schistosoma mansoni chromatin regulatory protein sir2 0.0127 0.035 0.0589
Brugia malayi NAD-dependent deacetylase SIRT1 0.014 0.0404 0.0404
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0157 0.047 0.047
Schistosoma mansoni hypothetical protein 0.0072 0.0136 0.0228
Loa Loa (eye worm) proteasome subunit alpha type 7-1 0.0042 0.0017 0.0017
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0829 0.3127 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0059 0.0082 0.0463
Schistosoma mansoni hypothetical protein 0.0072 0.0136 0.0228
Plasmodium vivax proteasome subunit beta type-3, putative 0.0042 0.0017 0.0003
Giardia lamblia Encystation-specific protease 0.0059 0.0082 0.0763
Loa Loa (eye worm) hypothetical protein 0.046 0.167 0.167
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.014 0.0404 0.2283
Onchocerca volvulus 0.0535 0.1966 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0059 0.0082 0.0376
Onchocerca volvulus 0.0229 0.0754 0.3784
Echinococcus granulosus expressed protein 0.0738 0.277 0.8077
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0131 0.0225
Schistosoma mansoni neuronal calcium sensor 0.0046 0.003 0.0051
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0089 0.0202 0.0339
Toxoplasma gondii proteasome subunit beta type 1, putative 0.0135 0.0383 0.2092
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 0.4222
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Onchocerca volvulus 0.0071 0.0131 0.0586
Plasmodium falciparum serine repeat antigen 3 0.0059 0.0082 0.0376
Leishmania major proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0005
Trypanosoma brucei proteasome subunit alpha type-5, putative 0.0042 0.0017 0.0005
Loa Loa (eye worm) hypothetical protein 0.0762 0.2862 0.2862
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0084 0.0141
Leishmania major silent information regulator 2, putative 0.0127 0.035 0.2998
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0059 0.0082 0.0463
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Toxoplasma gondii heat shock protein hslv, putative 0.0042 0.0017 0.0003
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0127 0.035 0.1266
Brugia malayi EF hand family protein 0.0046 0.003 0.003
Loa Loa (eye worm) hypothetical protein 0.0205 0.0659 0.0659
Echinococcus granulosus Mastin 0.0121 0.0329 0.0959
Brugia malayi hypothetical protein 0.046 0.167 0.167
Mycobacterium ulcerans beta-lactamase 0.0071 0.0131 0.0258
Loa Loa (eye worm) hypothetical protein 0.0059 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0209 0.0679 0.0679
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0121 0.0329 0.0959
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0059 0.0082 0.0376
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Plasmodium falciparum serine repeat antigen 9 0.0059 0.0082 0.0376
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Loa Loa (eye worm) proteasome subunit alpha type 6 0.0042 0.0017 0.0017
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0131 0.0225
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0324 0.1132 0.4222
Echinococcus granulosus cathepsin b 0.071 0.2658 0.775
Leishmania major calmodulin, putative 0.0046 0.003 0.0129
Toxoplasma gondii cathepsin CPC1 0.0059 0.0082 0.0376
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Entamoeba histolytica EF-hand calcium-binding domain containing protein 0.0046 0.003 0.0384
Trichomonas vaginalis ran, putative 0.0042 0.0016 0.0091
Echinococcus multilocularis cathepsin L cysteine protease 0.0229 0.0754 0.2199
Loa Loa (eye worm) ctsf protein 0.0229 0.0754 0.0754
Schistosoma mansoni cathepsin F (C01 family) 0.0229 0.0754 0.1268
Onchocerca volvulus Peroxidasin homolog 0.035 0.1235 0.6249
Giardia lamblia Proteasome subunit beta type 4 precursor 0.0042 0.0017 0.0006
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 1
Schistosoma mansoni microtubule-associated protein tau 0.0683 0.2549 0.4286
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0324 0.1132 0.4222
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.014 0.0403 0.0677
Toxoplasma gondii peptidase family M13 protein 0.0277 0.0945 0.5303
Echinococcus multilocularis proteasome (prosome macropain) subunit alpha 0.0042 0.0017 0.0048
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0453 0.1643 0.5159
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Schistosoma mansoni chromatin regulatory protein sir2 0.0127 0.035 0.0589
Brugia malayi Proteasome A-type and B-type family protein 0.0042 0.0017 0.0017
Leishmania major importin beta-1 subunit, putative 0.0046 0.0033 0.0151
Trypanosoma brucei proteasome alpha 3 subunit, putative 0.0042 0.0017 0.0005
Plasmodium vivax centrin-1, putative 0.0046 0.003 0.0082
Brugia malayi Papain family cysteine protease containing protein 0.0059 0.0082 0.0082
Leishmania major cathepsin L-like protease 0.0229 0.0754 0.6617
Toxoplasma gondii prolyl endopeptidase 0.0135 0.0383 0.2092
Echinococcus multilocularis EF hand domain containing family member A2 0.0046 0.003 0.0089
Brugia malayi cathepsin L-like precursor 0.016 0.0482 0.0482
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0097 0.0235 0.083
Brugia malayi calpain 5 0.0097 0.0235 0.0235
Giardia lamblia Cathepsin B precursor 0.026 0.0879 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0067 0.0117 0.0196
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0135 0.0383 0.0643
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0002
Plasmodium vivax unspecified product 0.0128 0.0354 0.1931
Plasmodium vivax SET domain protein, putative 0.0059 0.0084 0.0387
Schistosoma mansoni subfamily T1A non-peptidase homologue (T01 family) 0.0042 0.0017 0.0028
Trypanosoma cruzi cysteine peptidase, putative 0.0229 0.0754 0.2794
Leishmania major phospholipase c-like protein 0.0046 0.003 0.0129
Loa Loa (eye worm) programmed cell death protein 6 0.0046 0.0032 0.0032
Brugia malayi cathepsin F-like cysteine proteinase 0.0059 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0042 0.0017 0.0048
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0354 0.4472
Onchocerca volvulus 0.0046 0.0032 0.0081
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0097 0.0235 0.133
Brugia malayi transcriptional regulator, Sir2 family protein 0.0127 0.035 0.035
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0046 0.003 0.0055
Trypanosoma cruzi cruzipain precursor, putative 0.0322 0.1122 0.4187
Loa Loa (eye worm) hypothetical protein 0.0123 0.0335 0.0335
Brugia malayi peptidase family M13 containing protein 0.0067 0.0117 0.0117
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0059 0.0082 0.0463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0121 0.0329 0.0329
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Brugia malayi Cytochrome P450 family protein 0.0051 0.0051 0.0051
Echinococcus multilocularis proteasome (prosome, macropain) subunit, beta 0.0088 0.0196 0.0572
Plasmodium falciparum serine repeat antigen 7 0.0059 0.0082 0.0376
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0059 0.0082 0.0376
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Brugia malayi aspartic protease BmAsp-2, identical 0.0157 0.047 0.047
Echinococcus multilocularis microtubule associated protein 2 0.0683 0.2549 0.7433
Giardia lamblia Proteasome subunit beta type 9 precursor 0.0042 0.0017 0.0006
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.014 0.0403 0.0677
Echinococcus granulosus proteasome subunit beta type 7 0.0042 0.0017 0.0048
Trypanosoma brucei calpain, putative 0.0097 0.0235 0.1965
Schistosoma mansoni calpain-2 (C02 family) 0.0097 0.0235 0.0396
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Toxoplasma gondii proteasome subunit alpha type 1, putative 0.0042 0.0017 0.0003
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0202 0.0588
Trichomonas vaginalis myosin light chain 1, putative 0.0046 0.003 0.0172
Trypanosoma cruzi calmodulin, putative 0.0046 0.003 0.0055
Loa Loa (eye worm) hypothetical protein 0.0071 0.0131 0.0131
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0127 0.035 0.4422
Onchocerca volvulus 0.0229 0.0754 0.3784
Loa Loa (eye worm) hypothetical protein 0.0069 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.071 0.2658 0.2658
Brugia malayi prolyl oligopeptidase family protein 0.0135 0.0383 0.0383
Schistosoma mansoni proteasome subunit beta 4 (T01 family) 0.0042 0.0017 0.0028
Onchocerca volvulus 0.0071 0.0131 0.0586
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0054 0.0062 0.0411
Onchocerca volvulus 0.0059 0.0084 0.0345
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0097 0.0235 0.083
Plasmodium falciparum serine repeat antigen 5 0.0059 0.0082 0.0376
Onchocerca volvulus 0.0149 0.0441 0.2178
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0485 0.1768 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0131 0.0381
Loa Loa (eye worm) hypothetical protein 0.0157 0.047 0.047
Onchocerca volvulus 0.0121 0.0329 0.1603
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0905 0.3428 0.9994
Leishmania major proteasome beta 7 subunit, putative 0.0042 0.0017 0.0005
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0131 0.0131
Plasmodium vivax vivapain-1 0.0128 0.0354 0.1931
Trypanosoma cruzi hslVU complex proteolytic subunit, threonine peptidase, Clan T(1), family T1B 0.0042 0.0017 0.0002
Loa Loa (eye worm) hypothetical protein 0.0485 0.1768 0.1768
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0085 0.0616
Trypanosoma cruzi proteasome beta 7 subunit, putative 0.0042 0.0017 0.0002
Trichomonas vaginalis calmodulin, putative 0.0046 0.0032 0.0183
Brugia malayi hypothetical protein 0.0157 0.047 0.047
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0135 0.0383 0.1388
Loa Loa (eye worm) cytochrome P450 family protein 0.0101 0.0249 0.0249
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Echinococcus multilocularis expressed protein 0.0738 0.277 0.8077
Brugia malayi Trypsin family protein 0.0121 0.0329 0.0329
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Leishmania major cathepsin L-like protease 0.0322 0.1122 0.9917
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Loa Loa (eye worm) calpain D 0.0097 0.0235 0.0235
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.0136 0.0228
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0131 0.022
Entamoeba histolytica cysteine protease, putative 0.0059 0.0082 0.1033
Echinococcus granulosus calpain 5 0.0324 0.1132 0.3299
Toxoplasma gondii HEAT repeat-containing protein 0.0057 0.0076 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0082 0.0463
Trypanosoma brucei hypothetical protein 0.0097 0.0235 0.1965
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0097 0.0235 0.083
Trypanosoma cruzi cytoskeleton-associated protein CAP5.5, putative 0.0097 0.0235 0.083
Schistosoma mansoni cathepsin s 0.0069 0.0123 0.0206
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0131 0.0225
Trichomonas vaginalis hypothetical protein 0.0097 0.0235 0.133
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Trichomonas vaginalis conserved hypothetical protein 0.0046 0.003 0.0172
Schistosoma mansoni cathepsin F (C01 family) 0.016 0.0482 0.081
Trypanosoma cruzi ATP-dependent protease subunit HslV, putative 0.0042 0.0017 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0082 0.0463
Trypanosoma brucei calpain-like protein, putative 0.0324 0.1132 1
Giardia lamblia Cathepsin B precursor 0.0059 0.0082 0.0763
Trypanosoma brucei centrin, putative 0.0046 0.003 0.0129
Onchocerca volvulus Peroxidase homolog 0.035 0.1235 0.6249
Plasmodium falciparum plasmepsin IV 0.0485 0.1768 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0042 0.0016 0.0047
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0082
Echinococcus granulosus calbindin 32 0.0046 0.0032 0.0094
Toxoplasma gondii aspartyl protease 0.0157 0.047 0.259
Echinococcus multilocularis sarcoplasmic calcium binding protein 0.0046 0.003 0.0089
Brugia malayi Cathepsin L-like precursor 0.0069 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Loa Loa (eye worm) peptidase family M13 containing protein 0.0205 0.0659 0.0659
Loa Loa (eye worm) hypothetical protein 0.0097 0.0235 0.0235
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0324 0.1132 0.4222
Entamoeba histolytica proteasome subunit beta type 3, putative 0.0042 0.0017 0.0209
Plasmodium vivax importin-beta 2, putative 0.0057 0.0076 0.034
Schistosoma mansoni hypothetical protein 0.0072 0.0136 0.0228
Echinococcus multilocularis NAD dependent deacetylase sirtuin 1 0.014 0.0404 0.1177
Brugia malayi Cathepsin L-like precursor 0.0229 0.0754 0.0754
Loa Loa (eye worm) hypothetical protein 0.0149 0.0441 0.0441
Brugia malayi Cathepsin L-like precursor 0.016 0.0482 0.0482
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 0.4222
Entamoeba histolytica proteasome subunit alpha type 3, putative 0.0042 0.0017 0.0209
Leishmania major proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0005
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0054 0.0062 0.0173
Brugia malayi proteasome subunit beta type 3 0.0042 0.0017 0.0017
Plasmodium vivax ATP-dependent protease subunit ClpQ, putative 0.0042 0.0017 0.0003
Trypanosoma brucei prolyl oligopeptidase, putative 0.0054 0.0062 0.0411
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0485 0.1768 0.1768
Schistosoma mansoni neuronal calcium sensor 0.0046 0.003 0.0051
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0253 0.085 0.3155
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Brugia malayi cathepsin L-like cysteine proteinase 0.0059 0.0082 0.0082
Brugia malayi calpain 5 0.0227 0.0746 0.0746
Entamoeba histolytica proteasome subunit beta type 6 precursor, putative 0.0042 0.0017 0.0209
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0069 0.0123 0.0123
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0131 0.0225
Entamoeba histolytica proteasome subunit beta Type 4 precursor, putative 0.0042 0.0017 0.0209
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Echinococcus multilocularis cysteine protease 0.0229 0.0754 0.2199
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Plasmodium vivax aspartyl proteinase, putative 0.0485 0.1768 1
Leishmania major cytoskeleton-associated protein CAP5.5, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Trypanosoma cruzi major cysteine proteinase, putative 0.0152 0.045 0.1642
Trypanosoma cruzi proteasome beta-1 subunit, putative 0.0042 0.0017 0.0002
Onchocerca volvulus Dual oxidase homolog 0.035 0.1235 0.6249
Trypanosoma brucei proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0005
Trichomonas vaginalis centrin, putative 0.0046 0.003 0.0172
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0002
Echinococcus multilocularis cathepsin b 0.071 0.2658 0.775
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0059 0.0082 0.0463
Trichomonas vaginalis Clan CA, family C2, calpain-like cysteine peptidase 0.0097 0.0235 0.133
Leishmania major calmodulin-like protein 0.0046 0.003 0.0129
Toxoplasma gondii cathepsin B 0.026 0.0879 0.4922
Loa Loa (eye worm) proteasome subunit alpha type 3 0.0042 0.0017 0.0017
Trypanosoma brucei proteasome subunit beta type-2, putative 0.0088 0.0196 0.1616
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.026 0.0879 0.1477
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Giardia lamblia Hypothetical protein 0.0127 0.035 0.3877
Leishmania major cathepsin L-like protease 0.0322 0.1122 0.9917
Toxoplasma gondii calpain family cysteine protease domain-containing protein 0.0097 0.0235 0.1251
Brugia malayi Ets-domain containing protein 0.0143 0.0417 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Echinococcus multilocularis proteasome (prosome macropain) subunit beta type 0.0042 0.0017 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.016 0.0482 0.2723
Giardia lamblia Cathepsin L precursor 0.0059 0.0082 0.0763
Trypanosoma cruzi 20S proteasome subunit 0.0088 0.0196 0.0682
Loa Loa (eye worm) hypothetical protein 0.014 0.0404 0.0404
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0059 0.0082 0.0138
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Echinococcus granulosus cathepsin L cysteine protease 0.0128 0.0354 0.1033
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0485 0.1768 0.5157
Schistosoma mansoni reticulocalbin 0.0046 0.003 0.0051
Brugia malayi Trypsin family protein 0.0121 0.0329 0.0329
Giardia lamblia Cathepsin B precursor 0.0059 0.0082 0.0763
Brugia malayi Cytochrome P450 family protein 0.0101 0.0249 0.0249
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0131 0.0739
Schistosoma mansoni importin beta-1 0.0057 0.0076 0.0127
Trypanosoma brucei centrin-3 0.0046 0.003 0.0129
Echinococcus granulosus cysteine protease 0.0128 0.0354 0.1033
Brugia malayi Calmodulin-like protein 0.0046 0.003 0.003
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0131 0.0225
Trypanosoma brucei ATP-dependent protease subunit HslV 0.0042 0.0017 0.0005
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Plasmodium falciparum proteasome subunit alpha type-3, putative 0.0042 0.0017 0.0003
Brugia malayi Cathepsin L-like precursor 0.0229 0.0754 0.0754
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Toxoplasma gondii proteasome subunit alpha2, protease of the acylase family and NTN hydrolase fold, putative 0.0042 0.0017 0.0003
Echinococcus granulosus GA binding protein alpha chain 0.0143 0.0417 0.1216
Entamoeba histolytica hypothetical protein, conserved 0.0046 0.0032 0.0408
Entamoeba histolytica calmodulin, putative 0.0046 0.003 0.0384
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Echinococcus granulosus calpain A 0.0324 0.1132 0.3299
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0059 0.0082 0.1033
Plasmodium vivax serine-repeat antigen (SERA) 0.0059 0.0082 0.0376
Schistosoma mansoni cathepsin C 0.0059 0.0082 0.0138
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Plasmodium falciparum plasmepsin VIII, putative 0.0157 0.047 0.259
Echinococcus multilocularis calpain 0.0324 0.1132 0.3299
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Loa Loa (eye worm) blistered cuticle protein 3 0.035 0.1235 0.1235
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0238 0.0793 0.0793
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0229 0.0754 0.4264
Loa Loa (eye worm) cysteine protease 0.0229 0.0754 0.0754
Echinococcus multilocularis calpain 7 (C02 family) 0.0324 0.1132 0.3299
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.071 0.2658 0.4469
Onchocerca volvulus 0.0137 0.0393 0.193
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0059 0.0084 0.0244
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.0482
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0131 0.1028
Trypanosoma cruzi proteasome subunit alpha type-1, putative 0.0042 0.0017 0.0002
Loa Loa (eye worm) calpain family protein 1 0.0632 0.2351 0.2351
Mycobacterium tuberculosis Conserved protein 0.0071 0.0131 0.0225
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0042 0.0017 0.0005
Entamoeba histolytica proteasome subunit alpha type 4, putative 0.0042 0.0017 0.0209
Loa Loa (eye worm) calpain family protein 1 0.0859 0.3247 0.3247
Onchocerca volvulus 0.0229 0.0754 0.3784
Echinococcus multilocularis cathepsin L 0.0128 0.0354 0.1033
Echinococcus granulosus proteasome prosome macropain subunit alpha 0.0042 0.0017 0.0048
Onchocerca volvulus 0.0046 0.003 0.0071
Entamoeba histolytica grainin 2 0.0046 0.003 0.0384
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0042 0.0017 0.0002
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0042 0.0017 0.0017
Trichomonas vaginalis calcium binding protein, putative 0.0046 0.003 0.0172
Trypanosoma cruzi proteasome alpha 1 subunit, putative 0.0042 0.0017 0.0002
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0059 0.0082 0.0376
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0059 0.0084 0.0244
Echinococcus granulosus subfamily T1A non peptidase ue 0.0042 0.0017 0.0048
Schistosoma mansoni calpain C (C02 family) 0.0324 0.1132 0.1903
Trichomonas vaginalis esterase, putative 0.0071 0.0131 0.0739
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Echinococcus granulosus GTP binding nuclear protein Ran 0.0042 0.0016 0.0047
Trichomonas vaginalis Family T1, proteasome alpha subunit, threonine peptidase 0.0042 0.0017 0.0094
Plasmodium vivax aspartyl protease, putative 0.0157 0.047 0.259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0082 0.0463
Trypanosoma brucei oligopeptidase b 0.0054 0.0062 0.0411
Toxoplasma gondii calcium-dependent protein kinase 0.0046 0.0032 0.0093
Loa Loa (eye worm) proteasome A-type and B-type family protein 0.0042 0.0017 0.0017
Plasmodium vivax proteasome subunit beta type-2, putative 0.0088 0.0196 0.1028
Trypanosoma cruzi kinesin, putative 0.0227 0.0746 0.2764
Plasmodium falciparum proteasome subunit beta type-2, putative 0.0088 0.0196 0.1028
Onchocerca volvulus Peroxidase homolog 0.035 0.1235 0.6249
Schistosoma mansoni calpain-7 (C02 family) 0.0327 0.1144 0.1923
Trichomonas vaginalis calmodulin, putative 0.0046 0.003 0.0172
Echinococcus granulosus cathepsin l1 0.016 0.0482 0.1404
Toxoplasma gondii centrin, putative 0.0046 0.003 0.0082
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0059 0.0082 0.0376
Entamoeba histolytica cysteine proteinase, putative 0.0229 0.0754 0.9516
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0097 0.0235 0.083
Loa Loa (eye worm) proteasome subunit beta type 1 0.0135 0.0383 0.0383
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.2567 1 1
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0238 0.0793 0.2939
Echinococcus granulosus cathepsin L cysteine proteinase 0.0229 0.0754 0.2199
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Plasmodium vivax unspecified product 0.0069 0.0123 0.0608
Trypanosoma brucei kinesin, putative 0.0227 0.0746 0.6546
Plasmodium vivax calpain, putative 0.0324 0.1132 0.6365
Loa Loa (eye worm) hypothetical protein 0.0069 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0205 0.0659 0.0659
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0127 0.035 0.1022
Echinococcus granulosus microtubule associated protein 2 0.0683 0.2549 0.7433
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0046 0.0033 0.0186
Leishmania major proteasome beta 2 subunit, putative 0.0042 0.0017 0.0005
Trypanosoma brucei cytoskeleton-associated protein CAP5.5, putative 0.0097 0.0235 0.1965
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0131 0.0225
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.071 0.2658 0.4469
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Brugia malayi Trypsin-like protease protein 5 0.0121 0.0329 0.0329
Loa Loa (eye worm) hypothetical protein 0.0277 0.0945 0.0945
Plasmodium vivax proteasome subunit alpha type-4, putative 0.0042 0.0017 0.0003
Brugia malayi Pre-SET motif family protein 0.0412 0.148 0.148
Trypanosoma cruzi proteasome beta 6 subunit, putative 0.0135 0.0383 0.1388
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0324 0.1132 0.4222
Schistosoma mansoni hypothetical protein 0.0072 0.0136 0.0228
Echinococcus multilocularis Proteasome subunit alpha type 7 0.0042 0.0017 0.0048
Giardia lamblia Hypothetical protein 0.0046 0.0032 0.0189
Echinococcus granulosus calmodulin 0.0046 0.003 0.0089
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Loa Loa (eye worm) hypothetical protein 0.0059 0.0082 0.0082
Trichomonas vaginalis set domain proteins, putative 0.0469 0.1705 0.9641
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0131 0.0258
Entamoeba histolytica calpain family cysteine protease, putative 0.0097 0.0235 0.2969
Brugia malayi Papain family cysteine protease containing protein 0.0128 0.0354 0.0354
Leishmania major cathepsin L-like protease 0.0229 0.0754 0.6617
Trypanosoma cruzi cysteine peptidase, putative 0.0322 0.1122 0.4187
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0553
Schistosoma mansoni cercarial elastase (S01 family) 0.0121 0.0329 0.0553
Trypanosoma cruzi cysteine peptidase, putative 0.0322 0.1122 0.4187
Loa Loa (eye worm) PAS-3 protein 0.0042 0.0017 0.0017
Echinococcus multilocularis programmed cell death protein 0.0046 0.003 0.0089
Echinococcus granulosus endothelin converting enzyme 1 0.0277 0.0945 0.2757
Onchocerca volvulus 0.0229 0.0754 0.3784
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0042 0.0017 0.0028
Toxoplasma gondii EF hand domain-containing protein 0.0046 0.003 0.0082
Plasmodium falciparum plasmepsin VI 0.0485 0.1768 1
Giardia lamblia Cathepsin B precursor 0.026 0.0879 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0412 0.148 0.148
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0059 0.0082 0.1033
Echinococcus granulosus calpain A 0.0905 0.3429 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.026 0.0879 0.7733
Loa Loa (eye worm) hypothetical protein 0.0859 0.3247 0.3247
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0067 0.0117 0.0196
Brugia malayi calpain family protein 1 0.0859 0.3247 0.3247
Leishmania major calmodulin-like protein 0.0046 0.003 0.0129
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0059 0.0082 0.0763
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0128 0.0354 0.3033
Giardia lamblia Cysteine protease 0.0059 0.0082 0.0763
Brugia malayi Animal haem peroxidase family protein 0.035 0.1235 0.1235
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0067 0.0117 0.0196
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Schistosoma mansoni hypothetical protein 0.0121 0.0329 0.0553
Brugia malayi proteasome subunit alpha type 2 0.0042 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0354 0.4472
Leishmania major hypothetical protein, conserved 0.0046 0.0032 0.0146
Loa Loa (eye worm) animal heme peroxidase 0.035 0.1235 0.1235
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0121 0.0329 0.0959
Loa Loa (eye worm) hypothetical protein 0.016 0.0482 0.0482
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0229 0.0754 0.2199
Brugia malayi Animal haem peroxidase family protein 0.035 0.1235 0.1235
Echinococcus granulosus proteasome subunit alpha type 2 0.0042 0.0017 0.0048
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0137 0.0393 0.0393
Plasmodium falciparum proteasome subunit alpha type-4, putative 0.0042 0.0017 0.0003
Entamoeba histolytica Ran family GTPase 0.0042 0.0016 0.0202
Entamoeba histolytica calcium-dependent protein kinase 2, putative 0.0042 0.0017 0.0209
Echinococcus multilocularis hypothetical protein 0.0324 0.1132 0.3299
Onchocerca volvulus 0.0094 0.0221 0.105
Echinococcus multilocularis importin subunit beta 1 0.0057 0.0076 0.022
Schistosoma mansoni ef hand domain family member A2 0.0046 0.003 0.0051
Brugia malayi Proteasome subunit alpha type 1 0.0042 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Loa Loa (eye worm) hypothetical protein 0.0205 0.0659 0.0659
Schistosoma mansoni hypothetical protein 0.0094 0.0221 0.0372
Plasmodium vivax vivapain-2 0.0229 0.0754 0.4212
Mycobacterium leprae proteasome (beta subunit) PrcB 0.0238 0.0793 0.2384
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0084 0.0141
Trypanosoma cruzi cysteine protease, putative 0.0128 0.0354 0.1281
Echinococcus granulosus survival motor neuron protein 1 0.046 0.167 0.4868
Entamoeba histolytica cysteine protease, putative 0.0059 0.0082 0.1033
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0609 0.2258 0.2258
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Trypanosoma brucei mitochondrial calcium uptake 1 0.0046 0.003 0.0129
Trypanosoma cruzi proteasome alpha 7 subunit, putative 0.0042 0.0017 0.0002
Echinococcus granulosus peroxidasin 0.035 0.1235 0.36
Brugia malayi cathepsin L precursor 0.0059 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0059 0.0082 0.0463
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Echinococcus multilocularis transmembrane protease serine 3 0.0121 0.0329 0.0959
Entamoeba histolytica cysteine proteinase, putative 0.016 0.0482 0.6077
Echinococcus granulosus calcium uptake protein 1 0.0046 0.0032 0.0094
Wolbachia endosymbiont of Brugia malayi ATP-dependent protease peptidase subunit 0.0042 0.0017 0.5
Toxoplasma gondii proteasome subunit alpha type 5-2, putative 0.0042 0.0017 0.0003
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0089 0.0202 0.0202
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0143 0.0417 0.0417
Echinococcus multilocularis calmodulin 0.0046 0.003 0.0089
Onchocerca volvulus 0.016 0.0482 0.2386
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0127 0.035 0.4422
Schistosoma mansoni proteasome catalytic subunit 2 (T01 family) 0.0042 0.0017 0.0028
Brugia malayi proteasome subunit alpha type 1 0.0042 0.0017 0.0017
Plasmodium vivax aspartyl protease, putative 0.0344 0.1212 0.6822
Trypanosoma cruzi caltractin, putative 0.0046 0.003 0.0055
Plasmodium falciparum proteasome subunit beta type-4 0.0042 0.0017 0.0003
Brugia malayi 20S proteasome alpha5 subunit 0.0042 0.0017 0.0017
Schistosoma mansoni reticulocalbin 0.0046 0.0032 0.0054
Loa Loa (eye worm) hypothetical protein 0.0071 0.0131 0.0131
Loa Loa (eye worm) hypothetical protein 0.0071 0.0131 0.0131
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0157 0.047 0.079
Toxoplasma gondii aspartyl protease ASP5 0.0117 0.0313 0.1697
Echinococcus multilocularis endothelin converting enzyme 1 0.0277 0.0945 0.2757
Trypanosoma brucei Calpain-like protein 1.2 0.0097 0.0235 0.1965
Loa Loa (eye worm) proteasome subunit beta type 3 0.0042 0.0017 0.0017
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0238 0.0793 0.4481
Giardia lamblia Cathepsin L precursor 0.0059 0.0082 0.0763
Schistosoma mansoni hypothetical protein 0.0097 0.0235 0.0396
Trypanosoma cruzi prolyl endopeptidase 0.0135 0.0383 0.1388
Loa Loa (eye worm) hypothetical protein 0.0057 0.0076 0.0076
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0089 0.0202 0.0588
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0059 0.0082 0.0082
Onchocerca volvulus 0.0229 0.0754 0.3784
Giardia lamblia 20S proteasome alpha subunit 5 0.0042 0.0017 0.0006
Plasmodium falciparum plasmepsin I 0.0485 0.1768 1
Schistosoma mansoni proteasome catalytic subunit 3 (T01 family) 0.0238 0.0793 0.1333
Echinococcus granulosus proteasome subunit beta t family 0.0042 0.0017 0.0048
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0202 0.0588
Echinococcus multilocularis calumenin 0.0046 0.0032 0.0094
Loa Loa (eye worm) proteasome subunit alpha type 2 0.0042 0.0017 0.0017
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0089 0.0202 0.0588
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0754 0.4264
Loa Loa (eye worm) fibroinase 0.0229 0.0754 0.0754
Schistosoma mansoni hypothetical protein 0.0046 0.003 0.0051
Plasmodium vivax proteasome subunit alpha type-6, putative 0.0042 0.0017 0.0003
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0324 0.1132 0.4222
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0089 0.0202 0.0202
Brugia malayi proteasome subunit beta type 2 0.0088 0.0196 0.0196
Plasmodium falciparum proteasome subunit alpha type-5, putative 0.0042 0.0017 0.0003
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0127 0.035 0.1022
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0829 0.3127 1
Echinococcus granulosus NAD dependent deacetylase sirtuin 1 0.014 0.0404 0.1177
Leishmania major proteasome alpha 5 subunit, putative,20S proteasome subunit alpha 5, (putative) 0.0042 0.0017 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0059 0.0084 0.0141
Brugia malayi Trypsin family protein 0.0121 0.0329 0.0329
Entamoeba histolytica proteasome subunit alpha type 6, putative 0.0042 0.0017 0.0209
Trypanosoma brucei proteasome alpha 2 subunit, putative 0.0042 0.0017 0.0005
Loa Loa (eye worm) hypothetical protein 0.0632 0.2351 0.2351
Brugia malayi Cathepsin L-like precursor 0.0229 0.0754 0.0754
Schistosoma mansoni hypothetical protein 0.0121 0.0329 0.0553
Trypanosoma brucei proteasome beta 7 subunit 0.0042 0.0017 0.0005
Schistosoma mansoni proteasome subunit beta 3 (T01 family) 0.0042 0.0017 0.0028
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0059 0.0082 0.0376
Brugia malayi hypothetical protein 0.0157 0.047 0.047
Schistosoma mansoni calmodulin 0.0046 0.003 0.0051
Onchocerca volvulus Cathepsin L homolog 0.0059 0.0082 0.0335
Plasmodium vivax aspartyl protease, putative 0.0344 0.1212 0.6822
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Trypanosoma cruzi CAMK/CAMKL family protein kinase, putative 0.0046 0.003 0.0055
Entamoeba histolytica calpain large subunit domain III containing protein 0.0227 0.0746 0.9416
Loa Loa (eye worm) fli-1 protein 0.0435 0.1572 0.1572
Plasmodium falciparum proteasome subunit alpha type-6, putative 0.0042 0.0017 0.0003
Echinococcus multilocularis enteropeptidase 0.0121 0.0329 0.0959
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0157 0.047 0.259
Brugia malayi calcium-binding protein 0.0046 0.003 0.003
Trypanosoma brucei glucosamine 6-phosphate n-acetyltransferase 0.0097 0.0235 0.1965
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0059 0.0082 0.0463
Leishmania major hypothetical protein, conserved 0.0071 0.0131 0.1028
Trypanosoma cruzi conserved protein 0.0097 0.0235 0.083
Entamoeba histolytica proteasome subunit beta type 5 precursor, putative 0.0238 0.0793 1
Brugia malayi Papain family cysteine protease containing protein 0.0059 0.0082 0.0082
Echinococcus granulosus calpain 7 C02 family 0.0324 0.1132 0.3299
Entamoeba histolytica cysteine proteinase, putative 0.0128 0.0354 0.4472
Loa Loa (eye worm) zinc metallopeptidase 4 0.0067 0.0117 0.0117
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 33 0.0046 0.0032 0.0062
Entamoeba histolytica hypothetical protein 0.0046 0.0033 0.0416
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0085 0.0109
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Loa Loa (eye worm) 20S proteasome alpha5 subunit 0.0042 0.0017 0.0017
Toxoplasma gondii proteasome subunit beta type, putative 0.0238 0.0793 0.4431
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0797 0.3003 0.8756
Echinococcus multilocularis calcium uptake protein 1 0.0046 0.0032 0.0094
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0322 0.1122 0.9917
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0128 0.0354 0.0596
Onchocerca volvulus 0.0046 0.003 0.0071
Brugia malayi Cytochrome P450 family protein 0.0051 0.0051 0.0051
Echinococcus multilocularis peroxidasin 0.035 0.1235 0.36
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0131 0.0225
Giardia lamblia Cathepsin B precursor 0.0059 0.0082 0.0763
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0121 0.0329 0.0959
Leishmania major cathepsin L-like protease 0.0322 0.1122 0.9917
Trichomonas vaginalis calcium binding protein, putative 0.0046 0.003 0.0172
Plasmodium falciparum serine repeat antigen 6 0.0059 0.0082 0.0376
Schistosoma mansoni proteasome subunit beta 2 (T01 family) 0.0088 0.0196 0.033
Schistosoma mansoni hypothetical protein 0.0609 0.2258 0.3796
Entamoeba histolytica proteasome subunit beta type 1, putative 0.0135 0.0383 0.4829
Trypanosoma cruzi proteasome subunit beta type-2, putative 0.0088 0.0196 0.0682
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0082 0.0463
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0135 0.0383 0.2164
Loa Loa (eye worm) proteasome subunit beta type 2 0.0088 0.0196 0.0196
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0754 0.4264
Trypanosoma cruzi major cysteine proteinase, putative 0.0059 0.0082 0.0249
Loa Loa (eye worm) hypothetical protein 0.0209 0.0679 0.0679
Loa Loa (eye worm) hypothetical protein 0.0157 0.047 0.047
Giardia lamblia Cathepsin L precursor 0.0059 0.0082 0.0763
Plasmodium vivax vivapain-2 0.0229 0.0754 0.4212
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0085 0.0109
Trypanosoma cruzi proteasome alpha 3 subunit, putative 0.0042 0.0017 0.0002
Plasmodium falciparum proteasome subunit alpha type-2, putative 0.0042 0.0017 0.0003
Leishmania major calpain protease-like protein 0.0097 0.0235 0.1965
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0229 0.0754 0.4264
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0131 0.0225
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0085 0.0075
Loa Loa (eye worm) animal heme peroxidase 0.035 0.1235 0.1235
Echinococcus multilocularis cysteine protease 0.0229 0.0754 0.2199
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Loa Loa (eye worm) cytochrome P450 family protein 0.0051 0.0051 0.0051
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0054 0.0062 0.0173
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0229 0.0754 0.4212
Leishmania major i/6 autoantigen-like protein 0.0046 0.003 0.0129
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0097 0.0235 0.083
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Loa Loa (eye worm) hypothetical protein 0.035 0.1235 0.1235
Mycobacterium ulcerans proteasome PrcB 0.0238 0.0793 0.241
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0097 0.0235 0.1965
Brugia malayi Peptidase family M13 containing protein 0.0277 0.0945 0.0945
Entamoeba histolytica cysteine protease, putative 0.0128 0.0354 0.4472
Onchocerca volvulus Cathepsin L homolog 0.0229 0.0754 0.3784
Loa Loa (eye worm) hypothetical protein 0.0121 0.0329 0.0329
Brugia malayi Animal haem peroxidase family protein 0.035 0.1235 0.1235
Brugia malayi Proteasome subunit alpha type 7-1 0.0042 0.0017 0.0017
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0324 0.1132 1
Brugia malayi calpain family protein 1 0.0859 0.3247 0.3247
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0085 0.0143
Onchocerca volvulus Prolyl endopeptidase homolog 0.0135 0.0383 0.1879
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0059 0.0082 0.0376
Echinococcus granulosus histone lysine methyltransferase setb 0.0059 0.0084 0.0244
Trypanosoma brucei protein I/6 0.0046 0.003 0.0129
Giardia lamblia Cathepsin L-like protease 0.0059 0.0082 0.0763
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.1965
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.026 0.0879 0.3265
Echinococcus multilocularis cathepsin L cysteine protease 0.0229 0.0754 0.2199
Onchocerca volvulus Cathepsin F homolog 0.0229 0.0754 0.3784
Leishmania major proteasome beta 3 subunit, putative 0.0042 0.0017 0.0005
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0131 0.0434
Trypanosoma cruzi proteasome subunit beta type-5, putative 0.0238 0.0793 0.2939
Trichomonas vaginalis Family T1, proteasome beta subunit, threonine peptidase 0.0088 0.0196 0.111
Loa Loa (eye worm) hypothetical protein 0.0209 0.0679 0.0679
Giardia lamblia Proteasome subunit beta type 1 0.0135 0.0383 0.4251
Brugia malayi Cathepsin L-like precursor 0.0229 0.0754 0.0754
Trypanosoma cruzi proteasome beta 3 subunit, putative 0.0042 0.0017 0.0002
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0329 0.0959
Entamoeba histolytica calmodulin, putative 0.0046 0.003 0.0384
Loa Loa (eye worm) aspartyl protease 6 0.0157 0.047 0.047
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0067 0.0117 0.0196
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0059 0.0082 0.0376
Trypanosoma brucei Calpain-like protein CALP1.3 0.0097 0.0235 0.1965
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0128 0.0354 0.1281
Entamoeba histolytica protein kinase, putative 0.0227 0.0746 0.9416
Schistosoma mansoni neuronal calcium sensor 0.0046 0.003 0.0051
Schistosoma mansoni ets-related 0.0435 0.1572 0.2642
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0042 0.0017 0.0028
Giardia lamblia Hypothetical protein 0.0059 0.0082 0.0763
Trypanosoma brucei proteasome subunit beta type-5, putative 0.0238 0.0793 0.6961
Schistosoma mansoni calmodulin related calcium binding protein 0.0046 0.003 0.0051
Onchocerca volvulus 0.0121 0.0329 0.1603
Loa Loa (eye worm) hypothetical protein 0.0071 0.0131 0.0131
Schistosoma mansoni calpain-7 (C02 family) 0.0327 0.1144 0.1923
Schistosoma mansoni cathepsin D (A01 family) 0.1542 0.5947 1
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0067 0.0117 0.0196
Echinococcus granulosus cathepsin L 0.0128 0.0354 0.1033
Trichomonas vaginalis calpain, putative 0.0097 0.0235 0.133
Onchocerca volvulus 0.0121 0.0329 0.1603
Plasmodium vivax proteasome subunit alpha type-5, putative 0.0042 0.0017 0.0003
Brugia malayi Animal haem peroxidase family protein 0.035 0.1235 0.1235
Leishmania major 20s proteasome beta 7 subunit, (putative) 0.0042 0.0017 0.0005
Schistosoma mansoni Nep2 peptidase (M13 family) 0.014 0.0403 0.0677
Trypanosoma cruzi centrin, putative 0.0046 0.003 0.0055
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0097 0.0235 0.083
Echinococcus granulosus Proteasome subunit alpha type 7 0.0042 0.0017 0.0048
Plasmodium falciparum serine repeat antigen 8 0.0059 0.0082 0.0376

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 83 uM Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli ChEMBL. No reference
Ki (binding) = 83 uM Inhibitory constant was determined against class A RTEM-1 Beta-lactamase from Escherichia coli ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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