Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor X | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0425 | 0.1522 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0178 | 0.0522 | 0.343 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0129 | 0.0321 | 0.2106 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Plasmodium falciparum | GAF domain-related protein, putative | 0.0129 | 0.0321 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.0522 | 0.0522 |
Mycobacterium leprae | conserved hypothetical protein | 0.0129 | 0.0321 | 0.5 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0178 | 0.0522 | 0.0522 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0178 | 0.0522 | 0.0522 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0425 | 0.1522 | 0.1522 |
Echinococcus multilocularis | acetylcholinesterase | 0.2516 | 1 | 1 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.1585 | 0.6225 | 0.6225 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0178 | 0.0522 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Echinococcus granulosus | carboxylesterase 5A | 0.2516 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Loa Loa (eye worm) | carboxylesterase | 0.0425 | 0.1522 | 0.1522 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2516 | 1 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2516 | 1 | 1 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0425 | 0.1522 | 0.1522 |
Loa Loa (eye worm) | hypothetical protein | 0.1535 | 0.6023 | 0.6023 |
Schistosoma mansoni | gliotactin | 0.0425 | 0.1522 | 0.1522 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0178 | 0.0522 | 1 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Toxoplasma gondii | hypothetical protein | 0.0129 | 0.0321 | 1 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.1585 | 0.6225 | 0.6225 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0425 | 0.1522 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0425 | 0.1522 | 0.1522 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0178 | 0.0522 | 0.0522 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.005 | 0 | 0.5 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0425 | 0.1522 | 1 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Brugia malayi | Carboxylesterase family protein | 0.0425 | 0.1522 | 0.1522 |
Brugia malayi | Carboxylesterase family protein | 0.2516 | 1 | 1 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Echinococcus granulosus | acetylcholinesterase | 0.2516 | 1 | 1 |
Onchocerca volvulus | 0.0425 | 0.1522 | 0.5 | |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Loa Loa (eye worm) | carboxylesterase | 0.0425 | 0.1522 | 0.1522 |
Brugia malayi | Carboxylesterase family protein | 0.0425 | 0.1522 | 0.1522 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.1585 | 0.6225 | 0.6225 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0178 | 0.0522 | 1 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Schistosoma mansoni | acetylcholinesterase | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0129 | 0.0321 | 0.2106 |
Giardia lamblia | hypothetical protein | 0.005 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0425 | 0.1522 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0178 | 0.0522 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1407 | 0.5501 | 0.5501 |
Echinococcus granulosus | neuroligin | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0129 | 0.0321 | 0.2106 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Brugia malayi | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Onchocerca volvulus | 0.0425 | 0.1522 | 0.5 | |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0178 | 0.0522 | 0.0522 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Loa Loa (eye worm) | hypothetical protein | 0.2516 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.005 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0129 | 0.0321 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2516 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2516 | 1 | 1 |
Onchocerca volvulus | 0.0425 | 0.1522 | 0.5 | |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Onchocerca volvulus | 0.0425 | 0.1522 | 0.5 | |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Loa Loa (eye worm) | hypothetical protein | 0.2516 | 1 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 0.1522 | 0.1522 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0178 | 0.0522 | 0.0522 |
Plasmodium vivax | hypothetical protein, conserved | 0.0129 | 0.0321 | 1 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Toxoplasma gondii | GAF domain-containing protein | 0.0129 | 0.0321 | 1 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Brugia malayi | Carboxylesterase family protein | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Loa Loa (eye worm) | carboxylesterase | 0.2516 | 1 | 1 |
Onchocerca volvulus | 0.0425 | 0.1522 | 0.5 | |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0178 | 0.0522 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Toxoplasma gondii | hypothetical protein | 0.0129 | 0.0321 | 1 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Echinococcus multilocularis | neuroligin | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0425 | 0.1522 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Echinococcus multilocularis | acetylcholinesterase | 0.2516 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0425 | 0.1522 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0129 | 0.0321 | 0.2106 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0425 | 0.1522 | 0.1522 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0178 | 0.0522 | 0.343 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.