Detailed information for compound 24795

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 147.133 | Formula: C4H9N3O3
  • H donors: 4 H acceptors: 3 LogP: -2 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=N)NCC(C(=O)O)O
  • InChi: 1S/C4H9N3O3/c5-4(6)7-1-2(8)3(9)10/h2,8H,1H2,(H,9,10)(H4,5,6,7)
  • InChiKey: JZDBZICMFDGMLL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major short chain dehydrogenase, putative 0.0024 0.0047 0.0035
Brugia malayi Probable protein farnesyltransferase beta subunit, putative 0.0042 0.016 0.0183
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0047 0.0047
Brugia malayi hypothetical protein 0.0024 0.0047 0.0054
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.0024 0.0047 0.0057
Brugia malayi Carboxylesterase family protein 0.0478 0.2795 0.3203
Brugia malayi nuclear receptor RXR 0.0091 0.0456 0.0522
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0048 0.0196 0.0224
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0098 0.0093
Leishmania major dehydrogenase-like protein 0.0024 0.0047 0.0035
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0178 0.0185
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0178 0.0185
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0028 0.0076 0.0209
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0075 0.0356 0.064
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Brugia malayi Steroid receptor seven-up type 2 0.0282 0.1608 0.1843
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Leishmania major protein kinase, putative 0.0026 0.0059 0.0049
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0055 0.0139
Onchocerca volvulus 0.0081 0.0393 0.0561
Onchocerca volvulus 0.0081 0.0393 0.0561
Leishmania major glucose transporter, lmgt1 0.0032 0.0098 0.0093
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0024 0.0047 0.0042
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0018 0.0016 0.0041
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0016 0.0041
Giardia lamblia 70 kDa peptidylprolyl isomerase, putative 0.0053 0.0226 0.0737
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0048 0.0196 0.0492
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0016 0.0016
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0528 0.1325
Echinococcus multilocularis Smad4 0.0026 0.0059 0.0059
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.0047 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1046 0.2626
Schistosoma mansoni heat shock protein 0.0045 0.0178 0.0446
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0055 0.0044
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni glucose transport protein 0.0103 0.0528 0.1325
Echinococcus multilocularis nuclear receptor nhr 48 0.0091 0.0456 0.0456
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Schistosoma mansoni immunophilin 0.0053 0.0226 0.0568
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0091 0.0456 0.0522
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Echinococcus multilocularis ribosomal protein L19 0.0026 0.0061 0.0061
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0059 0.0148
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0018 0.0016 0.0019
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase-like, putative 0.1459 0.8726 1
Onchocerca volvulus 0.0024 0.0047 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0055 0.0044
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0018 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0143 0.0772 0.1939
Brugia malayi hypothetical protein 0.0024 0.0047 0.0054
Toxoplasma gondii aspartyl protease ASP1 0.0048 0.0196 0.0206
Loa Loa (eye worm) hypothetical protein 0.0218 0.1225 0.1404
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0334 0.0334
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Onchocerca volvulus 0.0024 0.0047 0.0046
Brugia malayi Hsp90 protein 0.003 0.0086 0.0099
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0024 0.0047 0.0047
Giardia lamblia Heat shock protein HSP 90-alpha 0.0039 0.0138 0.0428
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0117 0.0293
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.016 0.0164
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0044
Mycobacterium tuberculosis Conserved protein 0.0075 0.0356 0.064
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0081 0.0393 0.0987
Echinococcus multilocularis FTZ F1 alpha 0.0193 0.1072 0.1072
Brugia malayi Hypothetical zinc metalloproteinase T16A9.4 0.0296 0.1692 0.1939
Leishmania major hypothetical protein, conserved 0.0031 0.0095 0.009
Leishmania major hypothetical protein, conserved 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0038 0.0135 0.0155
Onchocerca volvulus 0.0024 0.0047 0.0046
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0081 0.0391 0.0449
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.0024 0.0047 0.0057
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0072 0.034 0.0854
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.0501 0.1257
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0215 0.0228
Brugia malayi follicle stimulating hormone receptor 0.0248 0.1403 0.1608
Leishmania major 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Loa Loa (eye worm) hypothetical protein 0.0121 0.0635 0.0728
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Plasmodium falciparum glutathione reductase 0.0041 0.0151 0.0474
Brugia malayi MH1 domain containing protein 0.0026 0.0059 0.0068
Schistosoma mansoni hypothetical protein 0.0299 0.1711 0.4297
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Onchocerca volvulus 0.0024 0.0047 0.0046
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0024 0.0047 0.0042
Brugia malayi Protein kinase c protein 2 0.0046 0.0181 0.0208
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0528 0.1325
Echinococcus granulosus survival motor neuron protein 1 0.0476 0.2783 0.6989
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0024 0.0047 0.0118
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Loa Loa (eye worm) glutathione reductase 0.0041 0.0151 0.0174
Onchocerca volvulus 0.0081 0.0393 0.0561
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0059 0.0056
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0193 0.1072 0.1072
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Schistosoma mansoni family M13 non-peptidase homologue (M13 family) 0.0149 0.0806 0.2025
Echinococcus granulosus heat shock protein 90 0.0039 0.0138 0.0347
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0091 0.0456 0.0654
Leishmania major phospholipase A1, putative 0.0683 0.4035 0.4613
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Loa Loa (eye worm) hypothetical protein 0.0296 0.1692 0.1939
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0024 0.0047 0.0057
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0024 0.0047 0.0042
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0041 0.0151 0.0254
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0659 0.0738
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0047 0.0042
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0016 0.0016
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.019 0.1052 0.1205
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0178 0.0192
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0024 0.0047 0.0042
Schistosoma mansoni immunophilin 0.0053 0.0226 0.0568
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0091 0.0456 0.1144
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0042 0.0161 0.0166
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.0024 0.0047 0.0035
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0081 0.0393 0.0987
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0098 0.0093
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0282 0.1608 0.1608
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Schistosoma mansoni tar DNA-binding protein 0.019 0.1052 0.264
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0279 0.1593 0.1826
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0123 0.0647 0.1624
Plasmodium falciparum plasmepsin VI 0.0048 0.0196 0.063
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0224 0.1256 0.144
Trichomonas vaginalis conserved hypothetical protein 0.0488 0.2858 0.3262
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0047 0.0042
Schistosoma mansoni single-minded 0.0096 0.0485 0.1217
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Onchocerca volvulus Huntingtin homolog 0.0121 0.0635 0.0922
Onchocerca volvulus 0.0683 0.4035 0.5988
Schistosoma mansoni smad 0.0026 0.0059 0.0148
Onchocerca volvulus Phospholipase A2 homolog 0.0279 0.1593 0.235
Trypanosoma brucei FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0226 0.024
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0193 0.1072 0.2693
Schistosoma mansoni nuclear receptor 0.0091 0.0456 0.1144
Loa Loa (eye worm) hypothetical protein 0.0028 0.0074 0.0085
Echinococcus multilocularis BC026374 protein (S09 family) 0.0081 0.0393 0.0393
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.016 0.0164
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0193 0.1072 0.1229
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Echinococcus multilocularis geranylgeranyl transferase type I beta subunit 0.0042 0.016 0.016
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0059 0.0059
Echinococcus granulosus ribosomal protein L19 0.0026 0.0061 0.0153
Schistosoma mansoni coup transcription factor 0.0193 0.1072 0.2693
Schistosoma mansoni integrin alpha-ps 0.0075 0.0358 0.0898
Brugia malayi dehydrogenases, short chain protein 9 0.0024 0.0047 0.0054
Trypanosoma brucei heat shock protein 84, putative 0.003 0.0086 0.008
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0488 0.2858 0.3262
Loa Loa (eye worm) hypothetical protein 0.0075 0.0356 0.0408
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0356 0.0894
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0047 0.0118
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0659 0.1656
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Echinococcus multilocularis integrin alpha ps 0.0144 0.0775 0.0775
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.016 0.0164
Onchocerca volvulus 0.0054 0.0234 0.0324
Brugia malayi beta-lactamase family protein 0.0075 0.0356 0.0408
Brugia malayi hypothetical protein 0.0091 0.0456 0.0522
Mycobacterium leprae conserved hypothetical protein 0.0075 0.0356 0.1878
Trypanosoma cruzi short-chain dehydrogenase, putative 0.0024 0.0047 0.0042
Schistosoma mansoni geranylgeranyl transferase type II beta subunit 0.0042 0.016 0.0401
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 1
Echinococcus multilocularis steroid dehydrogenase 0.0024 0.0047 0.0047
Loa Loa (eye worm) thioredoxin reductase 0.0041 0.0151 0.0174
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0042 0.016 0.0401
Loa Loa (eye worm) hypothetical protein 0.0042 0.016 0.0183
Plasmodium falciparum heat shock protein 90, putative 0.0171 0.094 0.3249
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0014
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0226 0.0248
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0047 0.0042
Onchocerca volvulus 0.0024 0.0047 0.0046
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0024 0.0047 0.0118
Toxoplasma gondii peptidase family M13 protein 0.0296 0.1692 0.1923
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0048 0.0196 0.0196
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Brugia malayi Importin beta-1 subunit 0.0028 0.0074 0.0085
Echinococcus granulosus endothelin converting enzyme 1 0.0296 0.1692 0.4248
Loa Loa (eye worm) hypothetical protein 0.0224 0.1256 0.144
Schistosoma mansoni RAR-like nuclear receptor 0.0193 0.1072 0.2693
Mycobacterium ulcerans lipase LipD 0.0075 0.0356 0.039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0193 0.1072 0.1229
Brugia malayi Nuclear hormone receptor-like 1 0.0193 0.1072 0.1229
Loa Loa (eye worm) hypothetical protein 0.1128 0.6727 0.7709
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0093 0.0468 0.2557
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0055 0.0044
Schistosoma mansoni intermediate filament proteins 0.0054 0.0234 0.0587
Mycobacterium tuberculosis Conserved protein 0.0075 0.0356 0.064
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0018 0.0016 0.0016
Brugia malayi PHD-finger family protein 0.0051 0.0214 0.0246
Leishmania major short chain dehydrogenase, putative 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Entamoeba histolytica 90 kDa heat shock protein, putative 0.003 0.0086 0.008
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0016 0.0041
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0091 0.0456 0.0522
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0496 0.055
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0016 0.0041
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0123 0.0647 0.0647
Loa Loa (eye worm) nuclear receptor NHR-67 0.0091 0.0456 0.0522
Plasmodium vivax steroid dehydrogenase, putative 0.0024 0.0047 0.0107
Schistosoma mansoni carbonyl reductase 0.0024 0.0047 0.0118
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0016 0.0016
Schistosoma mansoni zinc finger protein 0.0091 0.0456 0.1144
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0104 0.053 0.2939
Leishmania major heat shock protein, putative 0.003 0.0086 0.008
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0234 0.0268
Loa Loa (eye worm) hypothetical protein 0.0102 0.0522 0.0598
Brugia malayi peptidase family M13 containing protein 0.0072 0.034 0.039
Echinococcus multilocularis Niemann Pick C1 protein 0.0139 0.0743 0.0743
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0048 0.0196 0.0206
Echinococcus multilocularis glycine receptor subunit beta 0.0018 0.0016 0.0016
Loa Loa (eye worm) zinc metallopeptidase 4 0.0072 0.034 0.039
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0215 0.0699
Plasmodium falciparum geranylgeranyltransferase, putative 0.0042 0.016 0.0503
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0081 0.0093
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0054 0.0231 0.0404
Brugia malayi Thioredoxin reductase 0.0041 0.0151 0.0174
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.023 0.0578
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0047 0.0057
Trypanosoma brucei heat shock protein 90, putative 0.0045 0.0178 0.0185
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0218 0.1225 0.1404
Brugia malayi 60S ribosomal protein L19 0.0026 0.0061 0.007
Echinococcus granulosus snurportin 1 0.0299 0.1711 0.4297
Trypanosoma cruzi short chain dehydrogenase, putative 0.0024 0.0047 0.0042
Leishmania major geranylgeranyltransferase, putative 0.0042 0.016 0.0164
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Echinococcus granulosus hypothetical protein 0.0024 0.0047 0.0118
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0189 0.1046 0.1198
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0083 0.0405 0.1017
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Schistosoma mansoni hypothetical protein 0.0124 0.0655 0.1645
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0022
Loa Loa (eye worm) hypothetical protein 0.0488 0.2858 0.3275
Onchocerca volvulus 0.0024 0.0047 0.0046
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0024 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 0.0443
Loa Loa (eye worm) hypothetical protein 0.0102 0.0522 0.0598
Leishmania major short chain dehydrogenase-like protein 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0091 0.0454 0.0521
Brugia malayi RNA, U transporter 1 0.008 0.0386 0.0442
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0029 0.0014
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0074 0.0074
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-59, BmFKBP59 0.0053 0.0226 0.0259
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0055 0.0044
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.023 0.0578
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0026 0.0061 0.0058
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0018 0.0016 0.0016
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0083 0.0405 0.0405
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0209 0.0221
Onchocerca volvulus 0.0024 0.0047 0.0046
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0209 0.0209
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0042 0.0161 0.0272
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0048 0.0196 0.0492
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0024 0.0047 0.0042
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Loa Loa (eye worm) hypothetical protein 0.0079 0.0382 0.0437
Echinococcus multilocularis protein dispatched 1 0.0048 0.0192 0.0192
Toxoplasma gondii heat shock protein 90, putative 0.0045 0.0178 0.0185
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0075 0.0356 0.064
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0028 0.0076 0.0177
Schistosoma mansoni heat shock protein 0.0045 0.0178 0.0446
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0199 0.0501
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0098 0.0093
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.0024 0.0047 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0047 0.0042
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0055 0.0052
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.0024 0.0047 0.0057
Schistosoma mansoni hypothetical protein 0.0097 0.0492 0.1235
Brugia malayi nuclear hormone receptor 0.0193 0.1072 0.1229
Echinococcus granulosus retinoic acid receptor rxr beta a 0.029 0.166 0.4168
Plasmodium vivax farnesyltransferase beta subunit, putative 0.0042 0.016 0.0503
Giardia lamblia Rab geranylgeranyltransferase 0.0042 0.016 0.0503
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0093 0.0468 0.085
Echinococcus granulosus oxidoreductase 0.0024 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0488 0.2858 0.3275
Echinococcus granulosus hypothetical protein 0.0024 0.0047 0.0118
Schistosoma mansoni geranylgeranyl transferase type I beta subunit 0.0042 0.016 0.0401
Schistosoma mansoni hypothetical protein 0.0032 0.0101 0.0254
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Plasmodium vivax aspartyl proteinase, putative 0.0048 0.0196 0.063
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0024 0.0047 0.0047
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0018 0.0016 0.0041
Schistosoma mansoni peptidase Clp (S14 family) 0.0082 0.0403 0.1011
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0018 0.0016 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Leishmania major glucose transporter, lmgt2 0.0032 0.0098 0.0093
Plasmodium vivax hypothetical protein, conserved 0.0024 0.0047 0.0107
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0091 0.0456 0.0456
Leishmania major 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Plasmodium falciparum endoplasmin, putative 0.0033 0.0103 0.0303
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.0024 0.0047 0.0035
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.1459 0.8726 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0091 0.0456 0.1144
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0024 0.0047 0.0035
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0047 0.0035
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0351 0.0351
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0525 0.0602
Schistosoma mansoni smad1 5 8 and 0.0026 0.0059 0.0148
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0029 0.0022
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Echinococcus multilocularis steroid dehydrogenase 0.0024 0.0047 0.0047
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.0024 0.0047 0.0057
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Echinococcus granulosus nAChR subunit 0.0018 0.0016 0.0041
Schistosoma mansoni lamin 0.0054 0.0234 0.0587
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Brugia malayi RNA binding protein 0.019 0.1052 0.1205
Mycobacterium ulcerans carboxylesterase, LipT 0.0081 0.0393 0.0432
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0334 0.0383
Plasmodium falciparum plasmepsin IV 0.0048 0.0196 0.063
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0047 0.0035
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0525 0.0602
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0528 0.1325
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Echinococcus multilocularis lamin 0.0054 0.0234 0.0234
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Giardia lamblia Heat shock protein HSP 90-alpha 0.0045 0.0178 0.0567
Echinococcus granulosus General substrate transporter 0.0089 0.044 0.1105
Schistosoma mansoni hypothetical protein 0.0284 0.1622 0.4072
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0209 0.0221
Echinococcus granulosus fetal alzheimer antigen falz 0.0046 0.0185 0.0464
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0073
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0018 0.0016 0.0041
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0029 0.0029
Schistosoma mansoni nuclear receptor nhr-48 0.0091 0.0456 0.1144
Schistosoma mansoni acetylcholinesterase 0.0081 0.0393 0.0987
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0156 0.0393
Brugia malayi Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II family protein 0.0683 0.4035 0.4624
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0017 0.0017
Mycobacterium ulcerans oxidoreductase 0.0024 0.0047 0.0035
Brugia malayi nuclear hormone receptor family member odr-7 0.0091 0.0456 0.0522
Schistosoma mansoni endoplasmin 0.0045 0.0178 0.0446
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0091 0.0456 0.1144
Loa Loa (eye worm) acetylcholinesterase 1 0.0478 0.2795 0.3203
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni retinoic acid receptor RXR 0.029 0.166 0.4168
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0076 0.0209
Mycobacterium leprae Possible regulatory protein 0.0025 0.0055 0.005
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1046 0.2626
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0488 0.2858 0.3262
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Echinococcus multilocularis snurportin 1 0.0299 0.1711 0.1711
Brugia malayi Integrin alpha pat-2 precursor 0.0321 0.1846 0.2116
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0209 0.0526
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0035
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0209 0.0221
Brugia malayi 3-oxo-5-alpha-steroid 4-dehydrogenase 1 0.1459 0.8726 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0098 0.0093
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0055 0.0139
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1459 0.8726 1
Mycobacterium ulcerans dehydrogenase 0.0024 0.0047 0.0035
Brugia malayi ecdysteroid receptor 0.0193 0.1072 0.1229
Echinococcus granulosus acetylcholinesterase 0.0478 0.2795 0.7018
Schistosoma mansoni neprilysin-2 (M13 family) 0.0149 0.0806 0.2025
Loa Loa (eye worm) hypothetical protein 0.0075 0.0356 0.0408
Echinococcus multilocularis survival motor neuron protein 1 0.0476 0.2783 0.2783
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.0024 0.0047 0.0035
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0055 0.0052
Mycobacterium ulcerans zinc metalloprotease 0.0296 0.1692 0.1923
Toxoplasma gondii heat shock protein HSP90 0.0045 0.0178 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0193 0.1072 0.1229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0193 0.1072 0.1229
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0042 0.0161 0.3737
Entamoeba histolytica trans-2,3-enoyl-CoA reductase, putative 0.0488 0.2858 0.3262
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0209 0.0229
Echinococcus multilocularis Rab geranylgeranyltransferase, beta subunit 0.0042 0.016 0.016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0193 0.1072 0.1229
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.1046 0.2626
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0193 0.1072 0.1229
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.016 0.0171
Brugia malayi Carboxylesterase family protein 0.0081 0.0393 0.045
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0209 0.0678
Loa Loa (eye worm) hypothetical protein 0.0091 0.0454 0.0521
Toxoplasma gondii ABC1 family protein 0.0075 0.0356 0.039
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0101 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0103 0.0528 0.0586
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0019
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0063 0.0159
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.034 0.0854
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0047 0.0035
Entamoeba histolytica hypothetical protein 0.0143 0.0772 0.0867
Loa Loa (eye worm) hypothetical protein 0.0218 0.1225 0.1404
Onchocerca volvulus 0.0081 0.0393 0.0561
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0313 0.1799 0.2052
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0059 0.0056
Echinococcus multilocularis smad 0.0026 0.0059 0.0059
Trypanosoma brucei 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0488 0.2858 0.3262
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0035
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0193 0.1072 0.1229
Leishmania major hypothetical protein, conserved 0.0075 0.0356 0.039
Loa Loa (eye worm) FKBP5 protein 0.0053 0.0226 0.0259
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0101 0.0101
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0477 0.2788 0.5225
Schistosoma mansoni smad1 5 8 and 0.0026 0.0059 0.0148
Echinococcus multilocularis musashi 0.0054 0.0234 0.0234
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0659 0.1212
Onchocerca volvulus 0.0024 0.0047 0.0046
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.0024 0.0047 0.0057
Brugia malayi dehydrogenases, short chain protein 2 0.0024 0.0047 0.0054
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0029 0.0044
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0209 0.0221
Echinococcus multilocularis synaptic glycoprotein sc2 0.0488 0.2858 0.2858
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0018 0.0016 0.0041
Trypanosoma cruzi short chain dehydrogenase, putative 0.0024 0.0047 0.0042
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0161 0.0166
Echinococcus multilocularis 3 oxo 5 alpha steroid 4 dehydrogenase, C terminal 0.0488 0.2858 0.2858
Trichomonas vaginalis heat shock protein, putative 0.0042 0.0161 0.0166
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0659 0.0659
Echinococcus granulosus ribosomal protein L19 0.0026 0.0061 0.0153
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Echinococcus granulosus tar DNA binding protein 0.019 0.1052 0.264
Schistosoma mansoni immunophilin FK506 binding protein FKBP12 0.0053 0.0226 0.0568
Leishmania major lanosterol synthase, putative 0.0266 0.1513 0.1718
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0528 0.0528
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Brugia malayi conserved hypotetical protein 0.0091 0.0456 0.0522
Echinococcus multilocularis peptidase Clp (S14 family) 0.0054 0.0231 0.0231
Brugia malayi hypothetical protein 0.0051 0.0215 0.0247
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0054 0.0231 0.0404
Loa Loa (eye worm) hypothetical protein 0.0121 0.0635 0.0728
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Schistosoma mansoni neuroligin 3 (S09 family) 0.0081 0.0393 0.0987
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0209 0.0526
Trypanosoma cruzi geranylgeranyl transferase type II beta subunit, putative 0.0042 0.016 0.0171
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0193 0.1072 0.1229
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Schistosoma mansoni protein farnesyltransferase subunit beta 0.0042 0.016 0.0401
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0042 0.016 0.0164
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Mycobacterium tuberculosis Probable oxidoreductase 0.0104 0.053 0.0968
Brugia malayi hypothetical protein 0.0143 0.0772 0.0885
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0055 0.0044
Toxoplasma gondii oxidoreductase, putative 0.0024 0.0047 0.0035
Echinococcus multilocularis neuroligin 0.0081 0.0393 0.0393
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0209 0.0229
Mycobacterium leprae probable zinc metalloprotease 0.0296 0.1692 1
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0102 0.0522 0.131
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1459 0.8726 1
Echinococcus multilocularis GPCR, family 2 0.0032 0.0101 0.0101
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Plasmodium vivax thioredoxin reductase, putative 0.0041 0.0151 0.0474
Schistosoma mansoni hypothetical protein 0.0069 0.0322 0.0808
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0024 0.0047 0.0786
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0018 0.0016 0.0019
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0193 0.1072 0.1229
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0356 0.039
Trypanosoma brucei protein farnesyltransferase beta subunit 0.0042 0.016 0.0164
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0017 0.0007
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0075 0.0356 0.0894
Echinococcus granulosus Niemann Pick C1 protein 0.0139 0.0743 0.1866
Loa Loa (eye worm) hypothetical protein 0.0042 0.016 0.0183
Mycobacterium tuberculosis Probable reductase 0.0093 0.0468 0.085
Trichomonas vaginalis type I geranylgeranyltransferase beta subunit, putative 0.0042 0.016 0.0164
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0188 0.1043 0.1043
Trypanosoma cruzi heat shock protein 90, putative 0.0019 0.0019 0.001
Echinococcus multilocularis fk506 binding protein 0.0053 0.0226 0.0226
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Echinococcus multilocularis expressed conserved protein 0.0091 0.0456 0.0456
Plasmodium vivax polyprenol reductase, putative 0.0488 0.2858 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0091 0.0456 0.0456
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0193 0.1072 0.2693
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0215 0.0235
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Brugia malayi hypothetical protein 0.0065 0.0298 0.0341
Echinococcus multilocularis nAChR subunit 0.0018 0.0016 0.0016
Schistosoma mansoni nuclear hormone receptor 0.0193 0.1072 0.2693
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Echinococcus granulosus carboxylesterase 5A 0.0478 0.2795 0.7018
Toxoplasma gondii Rab geranylgeranyl transferase type II beta subunit, putative 0.0042 0.016 0.0164
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0055 0.0044
Plasmodium vivax plasmepsin IV, putative 0.0048 0.0196 0.063
Echinococcus multilocularis retinol dehydrogenase 11 0.0024 0.0047 0.0047
Mycobacterium ulcerans short chain dehydrogenase 0.0896 0.5321 0.609
Brugia malayi hypothetical protein 0.0091 0.0456 0.0522
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0226 0.0248
Leishmania major short chain dehydrogenase/reductase, putative 0.0024 0.0047 0.0035
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0024 0.0047 0.0046
Entamoeba histolytica steroid 5-alpha reductase, putative 0.1459 0.8726 1
Trichomonas vaginalis endoplasmin, putative 0.0033 0.0103 0.0099
Brugia malayi MH1 domain containing protein 0.0026 0.0059 0.0068
Loa Loa (eye worm) hypothetical protein 0.0103 0.0525 0.0602
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0104 0.053 0.0968
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0047 0.0047
Schistosoma mansoni Smad4 0.0026 0.0059 0.0148
Schistosoma mansoni hypothetical protein 0.004 0.0147 0.037
Loa Loa (eye worm) hypothetical protein 0.0322 0.185 0.212
Brugia malayi intermediate filament protein 0.0054 0.0234 0.0268
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0024 0.0047 0.0042
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.0047 0.0035
Loa Loa (eye worm) TAR-binding protein 0.019 0.1052 0.1205
Mycobacterium tuberculosis Probable zinc metalloprotease Zmp1 0.0296 0.1692 0.3158
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Mycobacterium tuberculosis Possible ketoacyl reductase 0.0024 0.0047 0.0057
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.003 0.0086 0.0104
Plasmodium falciparum thioredoxin reductase 0.0041 0.0151 0.0474
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0024 0.0047 0.0047
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.0655 0.1645
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.1046 0.1046
Loa Loa (eye worm) hypothetical protein 0.0224 0.1256 0.144
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0082 0.0403 0.1359
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0215 0.0235
Loa Loa (eye worm) dehydrogenase 0.0024 0.0047 0.0054
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Loa Loa (eye worm) MH2 domain-containing protein 0.0375 0.217 0.2487
Loa Loa (eye worm) hypothetical protein 0.0046 0.0182 0.0209
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0149 0.0806 0.2025
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Brugia malayi Phospholipase A2 family protein 0.1128 0.6727 0.7709
Echinococcus multilocularis acetylcholinesterase 0.0478 0.2795 0.2795
Loa Loa (eye worm) hypothetical protein 0.0042 0.0156 0.0179
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0016 0.0019
Schistosoma mansoni cathepsin D (A01 family) 0.0142 0.0763 0.1916
Entamoeba histolytica hypothetical protein 0.0488 0.2858 0.3262
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0059 0.0056
Brugia malayi ecdysone receptor 0.0091 0.0456 0.0522
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0024 0.0047 0.0107
Echinococcus granulosus heat shock protein 90 0.0045 0.0178 0.0446
Trypanosoma cruzi heat shock protein 85, putative 0.0039 0.0138 0.0147
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Trypanosoma cruzi phospholipase A1, putative 0.0683 0.4035 0.4617
Loa Loa (eye worm) RNA binding protein 0.019 0.1052 0.1205
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Onchocerca volvulus 0.0488 0.2858 0.4234
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0047 0.0035
Trichomonas vaginalis protein farnesyltransferase beta subunit, putative 0.0042 0.016 0.0164
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0193 0.1072 0.2693
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.0024 0.0047 0.0057
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0117 0.0117
Plasmodium falciparum protein farnesyltransferase subunit beta 0.0042 0.016 0.0503
Echinococcus granulosus protein kinase C gamma type 0.0048 0.0195 0.049
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0356 0.039
Schistosoma mansoni nuclear hormone receptor 0.0091 0.0456 0.1144
Brugia malayi nuclear receptor NHR-88 0.0091 0.0456 0.0522
Onchocerca volvulus 0.0081 0.0393 0.0561
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0234 0.0268
Onchocerca volvulus 0.0054 0.0234 0.0324
Schistosoma mansoni thyroid hormone receptor 0.0317 0.1823 0.4577
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0024 0.0047 0.0042
Onchocerca volvulus 0.0025 0.0055 0.0058
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0074 0.0066
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0101 0.0101
Mycobacterium tuberculosis Probable oxidoreductase 0.0896 0.5321 1
Entamoeba histolytica hypothetical protein, conserved 0.0024 0.0047 0.0035
Schistosoma mansoni hypothetical protein 0.0077 0.0371 0.0932
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0496 0.055
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.0047 0.0035
Mycobacterium ulcerans oxidoreductase 0.0024 0.0047 0.0035
Trypanosoma cruzi FK506-binding protein (FKBP)-type peptidyl-prolyl isomerase, putative 0.0053 0.0226 0.0248
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0024 0.0047 0.0118
Mycobacterium ulcerans dehydrogenase/reductase 0.0024 0.0047 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0016 0.0041
Brugia malayi hypothetical protein 0.0091 0.0454 0.0521
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0044 0.0044
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Loa Loa (eye worm) dehydrogenase 0.0024 0.0047 0.0054
Mycobacterium ulcerans hypothetical protein 0.0075 0.0356 0.039
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.016 0.0164
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0024 0.0047 0.0118
Toxoplasma gondii prenyltransferase and squalene oxidase repeat-containing protein 0.0042 0.016 0.0164
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0018 0.0016 0.0041
Onchocerca volvulus 0.0683 0.4035 0.5988
Echinococcus granulosus intermediate filament protein 0.0054 0.0234 0.0587
Entamoeba histolytica Rab geranylgeranyltransferase beta subunit, putative 0.0042 0.016 0.0164
Mycobacterium ulcerans ketoacyl reductase 0.0024 0.0047 0.0035
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0024 0.0047 0.0054
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0491 0.1234
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0016 0.0019
Brugia malayi bZIP transcription factor family protein 0.0083 0.0405 0.0464
Loa Loa (eye worm) hypothetical protein 0.0243 0.1373 0.1574
Schistosoma mansoni neprilysin 0.0077 0.0371 0.0932
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0047 0.0042
Treponema pallidum heat shock protein 90 0.0042 0.0161 0.3737
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type , putative 0.0053 0.0226 0.024
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Echinococcus granulosus ecdysone induced protein 78C 0.0193 0.1072 0.2693
Echinococcus multilocularis protein farnesyltransferase subunit beta 0.0042 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.0296 0.1692 0.1939
Echinococcus granulosus protein farnesyltransferase subunit beta 0.0042 0.016 0.0401
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0098 0.0093
Plasmodium vivax 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0488 0.2858 1
Schistosoma mansoni hypothetical protein 0.0023 0.0044 0.0111
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0018 0.0016 0.0041
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni ap endonuclease 0.0019 0.0017 0.0042
Echinococcus granulosus expressed conserved protein 0.0091 0.0456 0.1145
Brugia malayi Probable ClpP-like protease 0.0082 0.0403 0.0462
Loa Loa (eye worm) heat shock protein 90 0.0045 0.0178 0.0204
Plasmodium falciparum 60S ribosomal protein L19 0.0026 0.0061 0.0155
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0046 0.0185 0.0464
Loa Loa (eye worm) hypothetical protein 0.0075 0.0356 0.0408
Echinococcus multilocularis tumor protein p63 0.0333 0.1918 0.1918
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0215 0.0699
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Onchocerca volvulus 0.0193 0.1072 0.1574
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0024 0.0047 0.0047
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0053 0.0226 0.024
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0156 0.0393
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0017 0.0042
Schistosoma mansoni tar DNA-binding protein 0.019 0.1052 0.264
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Schistosoma mansoni hypothetical protein 0.0031 0.0095 0.0238
Leishmania major GTP-binding protein, putative 0.0021 0.0029 0.0014
Schistosoma mansoni hypothetical protein 0.004 0.0147 0.037
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0024 0.0047 0.0042
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0344 0.0344
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0042 0.0161 0.0692
Brugia malayi Nuclear hormone receptor-like 1 0.0102 0.0522 0.0598
Trichomonas vaginalis heat shock protein, putative 0.0026 0.0063 0.0054
Trypanosoma cruzi hexose transporter 0.0032 0.0098 0.01
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Schistosoma mansoni tar DNA-binding protein 0.019 0.1052 0.264
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0488 0.2858 0.3262
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0491 0.0563
Leishmania major hypothetical protein, conserved 0.0024 0.0047 0.0035
Onchocerca volvulus Bile acid receptor homolog 0.0193 0.1072 0.1574
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0193 0.1072 0.1229
Loa Loa (eye worm) Smad1 0.0026 0.0059 0.0068
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.0047 0.0057
Schistosoma mansoni ran 0.0021 0.0029 0.0073
Echinococcus granulosus single minded 2 0.0071 0.0334 0.0838
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0024 0.0047 0.0035
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0193 0.1072 0.1574
Echinococcus granulosus Protein kinase C brain isozyme 0.0054 0.023 0.0578
Loa Loa (eye worm) beta-lactamase 0.0075 0.0356 0.0408
Leishmania major trypanothione reductase 0.0041 0.0151 0.0155
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0017 0.0007
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0026 0.0061 0.0058
Schistosoma mansoni tar DNA-binding protein 0.019 0.1052 0.264
Echinococcus granulosus steroid dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0102 0.0522 0.131
Schistosoma mansoni hypothetical protein 0.0674 0.3982 1
Echinococcus multilocularis lamin dm0 0.0054 0.0234 0.0234
Brugia malayi Carboxylesterase family protein 0.0081 0.0393 0.045
Schistosoma mansoni importin beta-1 0.0028 0.0074 0.0186
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0081 0.0393 0.0987
Echinococcus granulosus peptidase Clp S14 family 0.0054 0.0231 0.058
Echinococcus granulosus lamin 0.0054 0.0234 0.0587
Schistosoma mansoni gliotactin 0.0081 0.0393 0.0987
Entamoeba histolytica heat shock transcription factor, putative 0.0098 0.0496 0.055
Brugia malayi orphan nuclear receptor NR2E1 0.0091 0.0456 0.0522
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0018 0.0016 0.0019
Toxoplasma gondii heat shock protein 75, putative 0.003 0.0086 0.008
Trypanosoma brucei geranylgeranyl transferase type II beta subunit, putative 0.0042 0.016 0.0164
Schistosoma mansoni nuclear hormone receptor 0.0091 0.0456 0.1144
Echinococcus multilocularis heat shock protein 90 0.0045 0.0178 0.0178
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0024 0.0047 0.0054
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0055 0.0044
Schistosoma mansoni bromodomain containing protein 0.013 0.0691 0.1736
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0189 0.1046 0.1046
Echinococcus multilocularis para nitrobenzyl esterase 0.0081 0.0393 0.0393
Plasmodium vivax endoplasmin, putative 0.0045 0.0178 0.0567
Brugia malayi nuclear hormone receptor 0.0091 0.0456 0.0522
Brugia malayi Cytochrome P450 family protein 0.0026 0.0061 0.0069
Onchocerca volvulus 0.0683 0.4035 0.5988
Echinococcus multilocularis General substrate transporter 0.0089 0.044 0.044
Echinococcus granulosus Smad4 0.0026 0.0059 0.0148
Loa Loa (eye worm) hypothetical protein 0.0053 0.0228 0.0261
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Entamoeba histolytica geranylgeranyl transferase beta subunit 0.0042 0.016 0.0164
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.0024 0.0047 0.0035
Mycobacterium ulcerans beta-lactamase 0.0075 0.0356 0.039
Plasmodium vivax importin-beta 2, putative 0.0028 0.0074 0.0201
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0034
Brugia malayi hypothetical protein 0.0476 0.2783 0.319
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0193 0.1072 0.1229
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0161 0.0185
Giardia lamblia Reductase, putative 0.0024 0.0047 0.0107
Brugia malayi hypothetical protein 0.0121 0.0635 0.0728
Giardia lamblia Synaptic glycoprotein SC2 0.0488 0.2858 1
Echinococcus granulosus glycine receptor subunit beta 0.0018 0.0016 0.0041
Plasmodium falciparum heat shock protein 90 0.0045 0.0178 0.0567
Loa Loa (eye worm) transcription factor SMAD2 0.0375 0.217 0.2487
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0193 0.1072 0.2693
Onchocerca volvulus 0.0024 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0356 0.039
Echinococcus granulosus para nitrobenzyl esterase 0.0081 0.0393 0.0987
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0016 0.0041
Leishmania major farnesyltransferase beta subunit 0.0042 0.016 0.0164
Brugia malayi Smad1 0.0026 0.0059 0.0068
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0032 0.0101 0.0254
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0016 0.0041
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0215 0.0699
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0074 0.0066
Echinococcus multilocularis jun protein 0.0083 0.0405 0.0405
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0028 0.0076 0.1542
Leishmania major protein kinase, putative 0.0026 0.0059 0.0049
Mycobacterium ulcerans short-chain dehydrogenase 0.0024 0.0047 0.0035
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0091 0.0456 0.0456
Onchocerca volvulus 0.0075 0.0356 0.0506
Schistosoma mansoni thyroid hormone receptor 0.0317 0.1823 0.4577
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Schistosoma mansoni Nep2 peptidase (M13 family) 0.0149 0.0806 0.2025
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Echinococcus granulosus thyroid hormone receptor alpha 0.0091 0.0456 0.1144
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0017 0.0019
Trypanosoma brucei glucose transporter 2A 0.0032 0.0098 0.0093
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0055 0.0044
Mycobacterium tuberculosis Possible oxidoreductase 0.0024 0.0047 0.0057
Entamoeba histolytica protein farnesyltransferase beta subunit, putative 0.0042 0.016 0.0164
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0018 0.0016 0.0019
Echinococcus multilocularis protein patched 0.0042 0.0156 0.0156
Brugia malayi hypothetical protein 0.0102 0.0522 0.0598
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0296 0.1692 0.4248
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0024 0.0047 0.0118
Trichomonas vaginalis esterase, putative 0.0075 0.0356 0.039
Echinococcus granulosus Nuclear hormone receptor HR96 0.0091 0.0456 0.1144
Toxoplasma gondii facilitative glucose transporter GT1 0.0103 0.0528 0.0586
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0059 0.0068
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0098 0.0093
Brugia malayi steroid hormone receptor 0.0193 0.1072 0.1229
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.0098 0.0093
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.003 0.0086 0.0086
Plasmodium falciparum polyprenol reductase, putative 0.0488 0.2858 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0659 0.0738
Toxoplasma gondii carbonyl reductase 1, putative 0.0024 0.0047 0.0035
Entamoeba histolytica 3-oxo-5-alpha-steroid 4-dehydrogenase domain-containing protein 0.0488 0.2858 0.3262
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0143 0.0772 0.0772
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0178 0.0192
Echinococcus multilocularis transient receptor potential cation channel 0.0024 0.0047 0.0047
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0193 0.1072 0.2693
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0101 0.0254
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Onchocerca volvulus 0.0146 0.079 0.1153
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0035
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0042 0.0029
Schistosoma mansoni hypothetical protein 0.0067 0.0311 0.0782
Loa Loa (eye worm) hypothetical protein 0.0048 0.0196 0.0224
Echinococcus multilocularis ribosomal protein L19 0.0026 0.0061 0.0061
Echinococcus granulosus FTZ F1 alpha 0.0193 0.1072 0.2693
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Trypanosoma brucei protein kinase, putative 0.005 0.0209 0.0221
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0066
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Schistosoma mansoni hypothetical protein 0.0103 0.0528 0.1325
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0193 0.1072 0.1229
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Echinococcus multilocularis X box binding protein 1 0.0284 0.1622 0.1622
Schistosoma mansoni transcription factor LCR-F1 0.0143 0.0772 0.1939
Onchocerca volvulus Heat shock factor protein 2 homolog 0.0098 0.0496 0.0714
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Brugia malayi HSF-type DNA-binding domain containing protein 0.0098 0.0496 0.0568
Loa Loa (eye worm) hypothetical protein 0.0146 0.079 0.0905
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0075 0.0356 0.064
Loa Loa (eye worm) hypothetical protein 0.0035 0.0117 0.0134
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0143 0.0772 0.1939
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0209 0.0221
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0082 0.0403 0.0403
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Onchocerca volvulus 0.0097 0.0492 0.0708
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0018 0.0016 0.0041
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0047 0.0057
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Loa Loa (eye worm) hypoxia-induced factor 1 0.0297 0.1699 0.1947
Leishmania major short chain dehydrogenase/reductase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.0024 0.0047 0.0035
Trichomonas vaginalis ran, putative 0.0021 0.0029 0.0014
Brugia malayi hypothetical protein 0.0322 0.185 0.212
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0046 0.0182 0.0182
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0226 0.024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0019
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0344 0.0863
Loa Loa (eye worm) hypothetical protein 0.0025 0.0055 0.0063
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0024 0.0047 0.0042
Entamoeba histolytica 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Loa Loa (eye worm) hypothetical protein 0.0049 0.0199 0.0229
Echinococcus multilocularis heat shock protein 90 0.0039 0.0138 0.0138
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1459 0.8726 1
Trypanosoma cruzi heat shock protein 90, putative 0.0045 0.0178 0.0192
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.0024 0.0047 0.0035
Brugia malayi nuclear hormone receptor family member nhr-6 0.0091 0.0456 0.0522
Schistosoma mansoni nuclear receptor 0.0091 0.0456 0.1144
Toxoplasma gondii 3-oxo-5-alpha-steroid 4-dehydrogenase 0.0488 0.2858 0.3262
Echinococcus granulosus neuroligin 0.0081 0.0393 0.0987
Trypanosoma cruzi Heat shock protein 83, putative 0.0045 0.0178 0.0192
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0035
Loa Loa (eye worm) carboxylesterase 0.0081 0.0393 0.045
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0019
Brugia malayi hypoxia-induced factor 1 0.0297 0.1699 0.1947
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0042 0.0036
Schistosoma mansoni glucose transport protein 0.0103 0.0528 0.1325
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0149 0.0806 0.2025
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0018 0.0016 0.0041
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Brugia malayi hypothetical protein 0.0081 0.0393 0.045
Leishmania major hypothetical protein, conserved 0.0024 0.0047 0.0035
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.004 0.0146 0.0167
Schistosoma mansoni carbonyl reductase 0.0024 0.0047 0.0118
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0018 0.0016 0.0019
Trypanosoma brucei hypothetical protein, conserved 0.0075 0.0356 0.039
Echinococcus granulosus BC026374 protein S09 family 0.0081 0.0393 0.0987
Brugia malayi Sugar transporter family protein 0.0103 0.0528 0.0605
Loa Loa (eye worm) hypothetical protein 0.0476 0.2783 0.319
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Brugia malayi TAR-binding protein 0.019 0.1052 0.1205
Echinococcus granulosus jun protein 0.0083 0.0405 0.1017
Schistosoma mansoni BC026374 protein (S09 family) 0.0081 0.0393 0.0987
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Toxoplasma gondii thioredoxin reductase 0.0041 0.0151 0.0155
Leishmania major peptidylprolyl isomerase-like protein 0.0053 0.0226 0.024
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Onchocerca volvulus 0.0049 0.0199 0.0273
Loa Loa (eye worm) hypothetical protein 0.0478 0.2795 0.3203
Schistosoma mansoni hypothetical protein 0.004 0.0147 0.037
Schistosoma mansoni cathepsin D (A01 family) 0.0142 0.0763 0.1916
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0356 0.0397
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Brugia malayi MH2 domain containing protein 0.0375 0.217 0.2487
Echinococcus granulosus synaptic glycoprotein sc2 0.0488 0.2858 0.7175
Mycobacterium tuberculosis Probable dehydrogenase 0.0024 0.0047 0.0057
Brugia malayi Cation transporter family protein 0.0018 0.0016 0.0019
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0024 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0016 0.0019
Trypanosoma cruzi ISWI complex protein 0.0031 0.0095 0.0097
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0055 0.0044
Mycobacterium tuberculosis Halimadienyl diphosphate synthase 0.0171 0.0936 0.1733
Echinococcus multilocularis acetylcholinesterase 0.0478 0.2795 0.2795
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Brugia malayi MH2 domain containing protein 0.0026 0.0059 0.0068
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0059 0.0148
Brugia malayi PAS domain containing protein 0.0096 0.0485 0.0555
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0193 0.1072 0.1229
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.0024 0.0047 0.0042
Loa Loa (eye worm) peptidase family M13 containing protein 0.0218 0.1225 0.1404
Mycobacterium tuberculosis Probable esterase LipL 0.0075 0.0356 0.064
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0061 0.0069
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0054 0.0231 0.1119
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1459 0.8726 1
Loa Loa (eye worm) carboxylesterase 0.0478 0.2795 0.3203
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0024 0.0047 0.0035
Brugia malayi Carboxylesterase family protein 0.0478 0.2795 0.3203
Trichomonas vaginalis glucose transporter, putative 0.0032 0.0098 0.0093
Trypanosoma brucei trypanothione reductase 0.0041 0.0151 0.0155
Echinococcus multilocularis tar DNA binding protein 0.019 0.1052 0.1052
Echinococcus multilocularis thyroid hormone receptor alpha 0.0317 0.1823 0.1823
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0042 0.0029
Brugia malayi Cation transporter family protein 0.0018 0.0016 0.0019
Brugia malayi MAP kinase sur-1 0.005 0.0209 0.024
Plasmodium vivax 60S ribosomal protein L19, putative 0.0026 0.0061 0.0155
Schistosoma mansoni smad1 5 8 and 0.0026 0.0059 0.0148
Loa Loa (eye worm) hypothetical protein 0.0097 0.0491 0.0563
Trichomonas vaginalis heat shock protein, putative 0.0045 0.0178 0.0185
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.0024 0.0047 0.0035
Brugia malayi beta-lactamase family protein 0.0075 0.0356 0.0408
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0117 0.0293
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Leishmania major glucose transporter, lmgt3 0.0032 0.0098 0.0093
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0098 0.01
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0055 0.0063
Loa Loa (eye worm) hypothetical protein 0.0026 0.0061 0.007
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Onchocerca volvulus 0.0071 0.0334 0.0473
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.016 0.0183
Brugia malayi Synaptic glycoprotein SC2 0.0488 0.2858 0.3275
Echinococcus granulosus acetylcholinesterase 0.0478 0.2795 0.7018
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Loa Loa (eye worm) hypothetical protein 0.0191 0.1057 0.1212
Loa Loa (eye worm) hypothetical protein 0.0054 0.0234 0.0268
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.034 0.0854
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.003 0.0086 0.0216
Brugia malayi beta-lactamase 0.0075 0.0356 0.0408
Trypanosoma cruzi protein farnesyltransferase, putative 0.0042 0.016 0.0171
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0026 0.0061 0.0058
Echinococcus granulosus lamin dm0 0.0054 0.0234 0.0587
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0193 0.1072 0.1229
Schistosoma mansoni integrin alpha-ps 0.0144 0.0775 0.1946
Loa Loa (eye worm) hypothetical protein 0.0075 0.0356 0.0408
Plasmodium vivax geranylgeranyl transferase type2 beta subunit, putative 0.0042 0.016 0.0503
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0055 0.0044
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0193 0.1072 0.2693
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0098 0.01
Onchocerca volvulus 0.0065 0.0298 0.0419
Trypanosoma cruzi 60S ribosomal protein L19, putative 0.0026 0.0061 0.0058
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Trypanosoma cruzi heat shock protein 85, putative 0.0045 0.0178 0.0192
Trypanosoma brucei oxidoreductase-like protein 0.0024 0.0047 0.0035
Mycobacterium ulcerans heat shock protein 90 0.0042 0.0161 0.0166
Loa Loa (eye worm) hypothetical protein 0.0478 0.2795 0.3203
Schistosoma mansoni heat shock protein 0.003 0.0086 0.0216
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0074 0.0066
Echinococcus granulosus GPCR family 2 0.0032 0.0101 0.0254
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0047 0.0118
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0124 0.0142
Brugia malayi Endoplasmin precursor 0.0045 0.0178 0.0204
Loa Loa (eye worm) hypothetical protein 0.0224 0.1256 0.144
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0018 0.0016 0.0041
Schistosoma mansoni integrin alpha 0.0321 0.1846 0.4635
Trichomonas vaginalis penicillin-binding protein, putative 0.0075 0.0356 0.039
Schistosoma mansoni ran 0.0021 0.0029 0.0073
Plasmodium vivax heat shock protein 86, putative 0.0045 0.0178 0.0567
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0248 0.1403 0.1608
Brugia malayi Nuclear hormone receptor E75 0.0091 0.0456 0.0522
Onchocerca volvulus 0.0024 0.0047 0.0046
Brugia malayi FKBP-type peptidyl-prolyl cis-trans isomerase-12, BmFKBP-12 0.0053 0.0226 0.0259
Mycobacterium tuberculosis Probable lipase LipD 0.0075 0.0356 0.064
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Echinococcus granulosus beta LACTamase domain containing family member 0.0075 0.0356 0.0894
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0351 0.0882
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Loa Loa (eye worm) hypothetical protein 0.0025 0.0057 0.0066
Echinococcus multilocularis telomerase reverse transcriptase subunit 0.0038 0.0135 0.0135
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Trypanosoma brucei glucose transporter 1E 0.0032 0.0098 0.0093
Schistosoma mansoni survival motor neuron protein 0.0097 0.0492 0.1235
Echinococcus granulosus Nuclear hormone receptor HR96 0.0091 0.0456 0.1144
Brugia malayi Carboxylesterase family protein 0.0081 0.0393 0.045
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0042 0.0029
Plasmodium vivax geranylgeranyltransferase, putative 0.0042 0.016 0.0503
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.0024 0.0047 0.0042
Plasmodium vivax heat shock protein 90, putative 0.003 0.0086 0.0244
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0209 0.0229
Onchocerca volvulus 0.0024 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0491 0.0491
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0156 0.0179
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0215 0.0228
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0193 0.1072 0.2693
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0029 0.0073
Loa Loa (eye worm) hypothetical protein 0.0102 0.0522 0.0598
Brugia malayi Retinol dehydrogenase 12 0.0024 0.0047 0.0054
Brugia malayi Integrin alpha cytoplasmic region family protein 0.0243 0.1373 0.1574
Schistosoma mansoni endothelin-converting enzyme-like 1 (damage-induced neuronal endopeptidase) 0.0072 0.034 0.0854
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0209 0.0229
Brugia malayi CHE-14 protein 0.0042 0.0156 0.0179
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Brugia malayi Cation transporter family protein 0.0018 0.0016 0.0019
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0659 0.1656
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0193 0.1072 0.1229
Echinococcus granulosus thioredoxin glutathione reductase 0.0041 0.0155 0.0389
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0101 0.0254
Entamoeba histolytica hypothetical protein 0.0143 0.0772 0.0867
Echinococcus multilocularis ecdysone induced protein 78C 0.0193 0.1072 0.1072
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Trichomonas vaginalis sugar transporter, putative 0.0032 0.0098 0.0093
Schistosoma mansoni lamin 0.0054 0.0234 0.0587
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0024 0.0047 0.0035
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0081 0.0393 0.0709
Echinococcus granulosus endoplasmin 0.0042 0.0161 0.0404
Schistosoma mansoni hypothetical protein 0.0674 0.3982 1
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0117 0.0293
Schistosoma mansoni zinc finger protein 0.004 0.0148 0.0372
Loa Loa (eye worm) endoplasmin 0.0045 0.0178 0.0204
Echinococcus granulosus 3 oxo 5 alpha steroid 4 dehydrogenase C terminal 0.0488 0.2858 0.7175
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 0.0443
Schistosoma mansoni hypothetical protein 0.0077 0.0371 0.0932
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0081 0.0093
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0075 0.0356 0.0408
Schistosoma mansoni aryl hydrocarbon receptor 0.0096 0.0485 0.1217
Loa Loa (eye worm) LGC-31 protein 0.0018 0.0016 0.0019
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0024 0.0047 0.0118
Plasmodium falciparum plasmepsin II 0.0048 0.0196 0.063
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0047 0.0057
Onchocerca volvulus 0.0091 0.0456 0.0654
Loa Loa (eye worm) hypothetical protein 0.0224 0.1256 0.144
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0018 0.0016 0.0041
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Echinococcus granulosus zinc finger protein 0.004 0.0148 0.0372
Loa Loa (eye worm) hypothetical protein 0.0084 0.0411 0.0471
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0016 0.0016
Brugia malayi Dehydrogenases, short chain protein 30 0.0024 0.0047 0.0054
Echinococcus granulosus integrin alpha ps 0.0069 0.0322 0.0808
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Brugia malayi MH2 domain containing protein 0.0026 0.0059 0.0068
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0054 0.023 0.023
Onchocerca volvulus Protein ultraspiracle homolog 0.0193 0.1072 0.1574
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0047 0.0118
Toxoplasma gondii ribosomal protein RPL19 0.0026 0.0061 0.0051
Trypanosoma brucei heat shock protein, putative 0.0045 0.0178 0.0185
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0055 0.0055
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0102 0.0522 0.131
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0226 0.0568
Loa Loa (eye worm) nuclear hormone receptor 0.018 0.0991 0.1136
Trypanosoma brucei phospholipase A1, putative 0.0683 0.4035 0.4613
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0093 0.0468 0.085
Trypanosoma cruzi lanosterol synthase, putative 0.0308 0.1768 0.2016
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0053 0.0226 0.0248
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0117 0.0293
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.0492 0.0564
Schistosoma mansoni hypothetical protein 0.0077 0.0371 0.0932
Loa Loa (eye worm) hypothetical protein 0.0296 0.1692 0.1939
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0193 0.1072 0.1072
Echinococcus multilocularis carbonyl reductase 1 0.0024 0.0047 0.0047
Brugia malayi photoreceptor-specific nuclear receptor 0.0193 0.1072 0.1229
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0103 0.0528 0.1325
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0075 0.0356 0.039
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0101 0.0116
Entamoeba histolytica heat shock protein 90, putative 0.0045 0.0178 0.0185
Trypanosoma cruzi phospholipase A1, putative 0.0683 0.4035 0.4617
Echinococcus granulosus smad 0.0026 0.0059 0.0148
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0055 0.0055
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Trichomonas vaginalis geranylgeranyl transferase type I beta subunit, putative 0.0042 0.016 0.0164
Trypanosoma cruzi lanosterol synthase, putative 0.0308 0.1768 0.2016
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0193 0.1072 0.2693
Loa Loa (eye worm) hypothetical protein 0.0069 0.0322 0.0369
Schistosoma mansoni immunophilin 0.0046 0.0182 0.0457
Giardia lamblia Hypothetical protein 0.0024 0.0047 0.0107
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0193 0.1072 0.2693
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0019
Trypanosoma brucei Heat shock protein 83, putative 0.0045 0.0178 0.0185
Echinococcus multilocularis serine threonine protein kinase 0.0048 0.0195 0.0195
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0018 0.0016 0.0019
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0189 0.1046 0.1198
Echinococcus multilocularis integrin alpha ps 0.0069 0.0322 0.0322
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0528 0.0528
Plasmodium falciparum peptidyl-prolyl cis-trans isomerase FKBP35 0.0053 0.0226 0.0737
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.0024 0.0047 0.0107
Trichomonas vaginalis fk506-binding protein, putative 0.0053 0.0226 0.024
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Entamoeba histolytica Ran family GTPase 0.0021 0.0029 0.0014
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0102 0.0522 0.0598
Trypanosoma brucei 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0018 0.0016 0.0019
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0193 0.1072 0.1072
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0024 0.0047 0.0035
Schistosoma mansoni endoplasmin 0.0045 0.0178 0.0446
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0039 0.0138 0.0347
Leishmania major fk506-binding protein 1-like protein 0.0053 0.0226 0.024
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, FKBP-type, putative 0.0053 0.0226 0.024
Loa Loa (eye worm) hypothetical protein 0.0081 0.0393 0.045
Loa Loa (eye worm) heat shock protein 75 0.003 0.0086 0.0099
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Trichomonas vaginalis heat shock protein, putative 0.0033 0.0103 0.0099
Trichomonas vaginalis 60S ribosomal protein L19, putative 0.0026 0.0061 0.0051
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 0.1359
Echinococcus granulosus X box binding protein 1 0.0284 0.1622 0.4072
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.0024 0.0047 0.0057
Mycobacterium tuberculosis Probable lipase LipE 0.0075 0.0356 0.064
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0047 0.0057
Trichomonas vaginalis steroid dehydrogenase, putative 0.0024 0.0047 0.0035
Schistosoma mansoni jun-related protein 0.0067 0.0311 0.0782
Leishmania major 3-keto-dihydrosphingosine reductase 0.0024 0.0047 0.0035
Entamoeba histolytica hypothetical protein 0.0023 0.0042 0.0029
Mycobacterium tuberculosis Probable oxidoreductase 0.0024 0.0047 0.0057
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0659 0.0738
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0101 0.0116
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Plasmodium falciparum plasmepsin I 0.0048 0.0196 0.063
Leishmania major hypothetical protein, conserved 0.0051 0.0215 0.0228
Trichomonas vaginalis conserved hypothetical protein 0.0488 0.2858 0.3262
Entamoeba histolytica hypothetical protein 0.0024 0.0047 0.0035
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0403 0.0443
Onchocerca volvulus 0.0024 0.0047 0.0046
Mycobacterium tuberculosis Probable hydrolase 0.0075 0.0356 0.064
Echinococcus granulosus tumor protein p63 0.0333 0.1918 0.4817
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP4 0.0046 0.0182 0.0457
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0102 0.0522 0.0522
Echinococcus granulosus RNA directed DNA polymerase 0.0038 0.0135 0.0339
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0082 0.0403 0.0443
Onchocerca volvulus Sepiapterin reductase homolog 0.0024 0.0047 0.0046
Mycobacterium ulcerans short-chain type oxidoreductase 0.0024 0.0047 0.0035
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.016 0.0171
Plasmodium falciparum heat shock protein 90, putative 0.0026 0.0063 0.0164
Trichomonas vaginalis immunophilin, putative 0.0053 0.0226 0.024
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.0024 0.0047 0.0057
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0525 0.0602
Trypanosoma cruzi trypanothione reductase, putative 0.0041 0.0151 0.0162
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0081 0.0393 0.0432
Trypanosoma cruzi ISWI complex protein 0.0031 0.0095 0.0097
Mycobacterium ulcerans FK-506 binding protein, peptidyl-prolyl cis-trans isomerase 0.0053 0.0226 0.024
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0193 0.1072 0.2693
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Giardia lamblia Grp94/Hsp90 0.0042 0.0161 0.0508
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0017 0.0019
Trichomonas vaginalis spcc417.12 protein, putative 0.0081 0.0393 0.0432
Echinococcus multilocularis carboxylesterase 5A 0.0478 0.2795 0.2795
Echinococcus multilocularis peptidyl prolyl cis trans isomerase FKBP4 0.0053 0.0226 0.0226
Trypanosoma brucei glucose transporter, putative 0.0032 0.0098 0.0093
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Brugia malayi tailless protein 0.0091 0.0456 0.0522
Leishmania major hypothetical protein, conserved 0.0024 0.0047 0.0035
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0478 0.2795 0.7018
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Loa Loa (eye worm) oxidoreductase 0.0024 0.0047 0.0054
Mycobacterium tuberculosis Probable dehydrogenase 0.0093 0.0468 0.085
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0081 0.0393 0.0987
Echinococcus granulosus carbonyl reductase 1 0.0024 0.0047 0.0118
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0044 0.0111
Mycobacterium ulcerans esterase/lipase LipP 0.0075 0.0356 0.039
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.016 0.0183
Toxoplasma gondii hypothetical protein 0.0028 0.0076 0.0068
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0055 0.0044
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Plasmodium falciparum steroid dehydrogenase, putative 0.0024 0.0047 0.0107
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0252 0.1429 0.1637
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0156 0.0156
Onchocerca volvulus 0.0075 0.0356 0.0506
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0018 0.0016 0.0019
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0329 0.0377
Plasmodium falciparum importin beta, putative 0.0028 0.0074 0.0201
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0103 0.0528 0.0528
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0024 0.0047 0.0035
Brugia malayi Bromodomain containing protein 0.0154 0.0837 0.0959
Schistosoma mansoni hypothetical protein 0.0032 0.0101 0.0254
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0082 0.0403 0.2162
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Trichomonas vaginalis geranylgeranyl transferase type beta subunit, putative 0.0042 0.016 0.0164
Echinococcus granulosus nuclear receptor nhr 48 0.0091 0.0456 0.1144
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0193 0.1072 0.1229
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0018 0.0016 0.0019
Schistosoma mansoni carbonyl reductase 0.0024 0.0047 0.0118
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0018 0.0016 0.0019
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 1
Echinococcus multilocularis integrin alpha ps 0.0144 0.0775 0.0775
Schistosoma mansoni hypothetical protein 0.0077 0.0371 0.0932
Entamoeba histolytica short chain dehydrogenase family protein 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0098 0.0496 0.0568
Leishmania major quinonoid dihydropteridine reductase 0.0024 0.0047 0.0035
Leishmania major oxidoreductase-like protein 0.0024 0.0047 0.0035
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0024 0.0047 0.0047
Brugia malayi Peptidase family M13 containing protein 0.0296 0.1692 0.1939
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0048 0.0196 0.0206
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0189 0.1046 0.2626
Schistosoma mansoni hypothetical protein 0.0032 0.0101 0.0254
Loa Loa (eye worm) steroid hormone receptor 0.0193 0.1072 0.1229
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0189 0.1046 0.2626
Echinococcus granulosus peptidyl prolyl cis trans isomerase FKBP1A 0.0053 0.0226 0.0568
Loa Loa (eye worm) platelet-activating factor acetylhydrolase 0.0683 0.4035 0.4624
Plasmodium falciparum geranylgeranyl transferase type2 beta subunit, putative 0.0042 0.016 0.0503
Loa Loa (eye worm) hypothetical protein 0.0224 0.1256 0.144
Leishmania major pteridine reductase 1 0.0024 0.0047 0.0035
Schistosoma mansoni glucose transport protein 0.0103 0.0528 0.1325
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0081 0.0393 0.0393
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0059 0.0059
Echinococcus granulosus retinol dehydrogenase 11 0.0024 0.0047 0.0118
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.0024 0.0047 0.0042
Plasmodium vivax hypothetical protein, conserved 0.0075 0.0356 0.1194
Giardia lamblia Prenyltransferase 0.0042 0.016 0.0503
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.0024 0.0047 0.0057
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0081 0.0393 0.0709
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0103 0.0528 0.0528
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0072 0.034 0.0854
Loa Loa (eye worm) ACC-1 protein 0.0018 0.0016 0.0019
Loa Loa (eye worm) peptidase family M13 containing protein 0.0218 0.1225 0.1404
Trypanosoma cruzi 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0488 0.2858 0.3267
Trypanosoma cruzi phospholipase A2-like protein, putative 0.0313 0.1799 0.2052
Echinococcus multilocularis retinol dehydrogenase 11 0.0024 0.0047 0.0047
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0193 0.1072 0.1072
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0117 0.0293
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.1711 0.1961
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.0655 0.0655
Toxoplasma gondii oxidoreductase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0177 0.0976 0.1118
Giardia lamblia Ribosomal protein L19 0.0026 0.0061 0.0155
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0018 0.0016 0.0019
Echinococcus multilocularis RNA directed DNA polymerase 0.0038 0.0135 0.0135
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0075 0.0356 0.0408
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0055 0.0044
Plasmodium vivax glutathione reductase, putative 0.0041 0.0151 0.0474
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Brugia malayi glutathione reductase 0.0041 0.0151 0.0174
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Mycobacterium tuberculosis Conserved protein 0.0075 0.0356 0.064
Giardia lamblia Short-chain dehydrogenase, putative 0.0024 0.0047 0.0107
Trypanosoma brucei lanosterol synthase 0.0308 0.1768 0.201
Echinococcus multilocularis endoplasmin 0.0042 0.0161 0.0161
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.1459 0.8726 1
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0082 0.0403 0.1011
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0024 0.0047 0.0035
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0209 0.0209
Brugia malayi nuclear receptor NHR-67 0.0091 0.0456 0.0522
Loa Loa (eye worm) carboxylesterase 0.0081 0.0393 0.045
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.0024 0.0047 0.0042
Onchocerca volvulus Huntingtin homolog 0.0121 0.0635 0.0922
Echinococcus granulosus heat shock protein 0.0045 0.0178 0.0446
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Schistosoma mansoni eyes absent homolog 0.0091 0.0454 0.1141
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0282 0.1608 0.4038
Loa Loa (eye worm) hypothetical protein 0.0145 0.0784 0.0898
Leishmania major 3-oxo-5-alpha-steroid 4-dehydrogenase-like protein 0.1459 0.8726 1
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0488 0.2858 0.7175
Echinococcus multilocularis geminin 0.0674 0.3982 0.3982
Loa Loa (eye worm) sugar transporter 0.0103 0.0528 0.0605
Loa Loa (eye worm) hypothetical protein 0.0075 0.0356 0.0408
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0046 0.0185 0.0185
Schistosoma mansoni hypothetical protein 0.0077 0.0371 0.0932
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0091 0.0456 0.0456
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0193 0.1072 0.1072
Trypanosoma cruzi heat shock protein, putative 0.003 0.0086 0.0087
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0209 0.0526
Loa Loa (eye worm) hypothetical protein 0.0044 0.017 0.0195
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0019
Echinococcus multilocularis conserved hypothetical protein 0.0024 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0082 0.0403 0.0462
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0018 0.0016 0.0019
Schistosoma mansoni family M13 unassigned peptidase (M13 family) 0.0077 0.0371 0.0932
Brugia malayi RNA recognition motif domain containing protein 0.019 0.1052 0.1205
Leishmania major hypothetical protein, conserved 0.0024 0.0047 0.0035
Schistosoma mansoni synaptic glycoprotein sc2 related 0.0488 0.2858 0.7175
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Trichomonas vaginalis heat shock protein, putative 0.0039 0.0138 0.014
Echinococcus multilocularis thioredoxin glutathione reductase 0.0041 0.0155 0.0155
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Plasmodium falciparum hexose transporter 0.0103 0.0528 0.1798
Mycobacterium leprae Probable lipase LipE 0.0075 0.0356 0.1878
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0193 0.1072 0.2693
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Echinococcus granulosus retinol dehydrogenase 11 0.0024 0.0047 0.0118
Brugia malayi Bromodomain containing protein 0.0079 0.0381 0.0436
Loa Loa (eye worm) integrin alpha pat-2 0.0495 0.2897 0.332
Entamoeba histolytica short chain dehydrogenase family protein 0.0024 0.0047 0.0035
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0082 0.0403 1
Schistosoma mansoni zinc finger protein 0.0031 0.0095 0.0238
Brugia malayi oxidoreductase 0.0024 0.0047 0.0054
Brugia malayi Dehydrogenases, short chain protein 2 0.0024 0.0047 0.0054
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0059 0.0056
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Echinococcus multilocularis oxidoreductase 0.0024 0.0047 0.0047
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0093 0.0468 0.085
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0491 0.0545
Loa Loa (eye worm) hypothetical protein 0.007 0.0329 0.0377
Trypanosoma brucei ISWI complex protein 0.0031 0.0095 0.009
Loa Loa (eye worm) hypothetical protein 0.0218 0.1225 0.1404
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.0024 0.0047 0.0107
Trichomonas vaginalis peptidylprolyl isomerase, putative 0.0053 0.0226 0.024
Plasmodium vivax heat shock protein, putative 0.0171 0.094 0.3249
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0093 0.0468 0.085
Echinococcus granulosus integrin alpha ps 0.0144 0.0775 0.1946
Treponema pallidum peptidyl-prolyl cis-trans isomerase, FKBP-type, 22 kDa (fklB) 0.0053 0.0226 0.5426
Echinococcus granulosus glycine receptor subunit alpha 1 0.0018 0.0016 0.0041
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0054
Echinococcus multilocularis heat shock protein 0.0045 0.0178 0.0178
Brugia malayi hypothetical protein 0.0033 0.0105 0.0121
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0091 0.0456 0.1144
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0209 0.0221
Trichomonas vaginalis D-aminoacylase, putative 0.0075 0.0356 0.039
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0063 0.0063
Leishmania major importin beta-1 subunit, putative 0.0023 0.0042 0.0029
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0018 0.0016 0.0019
Giardia lamblia FKBP-type peptidyl-prolyl cis-trans isomerase 0.0053 0.0226 0.0737
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0334 0.0364
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0193 0.1072 0.1229
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0209 0.024
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0018 0.0016 0.0016
Loa Loa (eye worm) DR-78 0.0091 0.0456 0.0522
Schistosoma mansoni short chain dehydrogenase 0.0024 0.0047 0.0118
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0019
Brugia malayi Nuclear hormone receptor E75 0.0091 0.0456 0.0522
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0659 0.0738
Onchocerca volvulus 0.0024 0.0047 0.0046
Schistosoma mansoni hypothetical protein 0.0042 0.0161 0.0405
Echinococcus multilocularis endothelin converting enzyme 1 0.0296 0.1692 0.1692
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Schistosoma mansoni ap endonuclease 0.0019 0.0017 0.0042
Echinococcus granulosus geminin 0.0674 0.3982 1
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.0024 0.0047 0.0042
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0034
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Leishmania major heat shock protein 83-1 0.0045 0.0178 0.0185
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0024 0.0047 0.0054
Brugia malayi Nuclear hormone receptor-like 1 0.0102 0.0522 0.0598
Brugia malayi heat shock protein 90 0.0045 0.0178 0.0204
Echinococcus granulosus WW domain containing oxidoreductase 0.0024 0.0047 0.0118
Echinococcus granulosus integrin alpha 3 0.0246 0.1393 0.3498
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0029 0.0044
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0057
Onchocerca volvulus 0.0091 0.0456 0.0654
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0234 0.0268
Brugia malayi nuclear receptor NHR-88 0.0193 0.1072 0.1229
Onchocerca volvulus 0.0075 0.0356 0.0506
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0209 0.0221
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0018 0.0016 0.0019
Schistosoma mansoni endothelin-converting enzyme-related 0.0072 0.034 0.0854
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0018 0.0016 0.0016
Mycobacterium ulcerans hypothetical protein 0.1459 0.8726 1
Loa Loa (eye worm) hypothetical protein 0.0088 0.0435 0.0498
Schistosoma mansoni hypothetical protein 0.0077 0.0371 0.0932
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0091 0.0456 0.0654
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Schistosoma mansoni hypothetical protein 0.007 0.0329 0.0826
Plasmodium vivax 70 kDa peptidylprolyl isomerase, putative 0.0053 0.0226 0.0737
Schistosoma mansoni hypothetical protein 0.004 0.0147 0.037
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.016 0.0171
Echinococcus granulosus geranylgeranyl transferase type I beta subunit 0.0042 0.016 0.0401
Onchocerca volvulus Phospholipase A2 homolog 0.1128 0.6727 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0156 0.016
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0193 0.1072 0.1229
Echinococcus multilocularis retinol dehydrogenase 13 0.0024 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0075 0.0358 0.041
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0193 0.1072 0.1229
Mycobacterium tuberculosis Carboxylesterase LipT 0.0081 0.0393 0.0709
Plasmodium falciparum 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0488 0.2858 1
Echinococcus granulosus importin subunit beta 1 0.0028 0.0074 0.0186
Schistosoma mansoni 60S ribosomal protein L19 0.0026 0.0061 0.0153
Loa Loa (eye worm) prenyltransferase and squalene oxidase repeat family protein 0.0042 0.016 0.0183
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.0024 0.0047 0.0042
Schistosoma mansoni patched 1 0.0042 0.0156 0.0393
Brugia malayi excitatory GABA receptor EXP-1A 0.0018 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0102 0.0522 0.0598
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0659 0.1656
Trypanosoma cruzi hexose transporter, putative 0.0032 0.0098 0.01
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0209 0.0221
Loa Loa (eye worm) hypothetical protein 0.0032 0.0101 0.0116
Trichomonas vaginalis 3-oxo-5-alpha-steroid 4-dehydrogenase, putative 0.0488 0.2858 0.3262
Loa Loa (eye worm) hypothetical protein 0.0193 0.1072 0.1229
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.0024 0.0047 0.0035
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0193 0.1072 0.1229
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0024 0.0047 0.0118
Trichomonas vaginalis geranylgeranyl transferase type II beta subunit, putative 0.0042 0.016 0.0164
Loa Loa (eye worm) hypothetical protein 0.0024 0.0047 0.0054
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0024 0.0047 0.0054
Schistosoma mansoni retinal dehydrogenase 0.0024 0.0047 0.0118
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0117 0.0293
Loa Loa (eye worm) hypothetical protein 0.0075 0.0356 0.0408
Echinococcus multilocularis zinc finger protein 0.004 0.0148 0.0148
Schistosoma mansoni steroid hormone receptor ad4bp 0.0193 0.1072 0.2693
Trypanosoma brucei short-chain dehydrogenase, putative 0.0024 0.0047 0.0035
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0104 0.053 0.0968
Mycobacterium ulcerans short chain dehydrogenase 0.0024 0.0047 0.0035
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0018 0.0016 0.0019
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0659 0.0738
Brugia malayi Prenyltransferase and squalene oxidase repeat family protein 0.0042 0.016 0.0183
Loa Loa (eye worm) hypothetical protein 0.0051 0.0213 0.0244
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0024 0.0047 0.0035
Entamoeba histolytica hypothetical protein 0.0143 0.0772 0.0867
Echinococcus multilocularis integrin alpha 3 0.0246 0.1393 0.1393
Schistosoma mansoni tar DNA-binding protein 0.019 0.1052 0.264
Schistosoma mansoni steroid dehydrogenase 0.0024 0.0047 0.0118
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0059 0.0068
Plasmodium vivax hexose transporter 0.0103 0.0528 0.1798
Loa Loa (eye worm) hypothetical protein 0.0051 0.0215 0.0247
Schistosoma mansoni nAChR subunit 0.0018 0.0016 0.0041
Brugia malayi Carboxylesterase family protein 0.0081 0.0393 0.045
Echinococcus multilocularis beta LACTamase domain containing family member 0.0075 0.0356 0.0356
Trichomonas vaginalis synaptic glycoprotein sc2, putative 0.0488 0.2858 0.3262
Mycobacterium ulcerans carveol-like dehydrogenase 0.0024 0.0047 0.0035
Loa Loa (eye worm) FKBP-type peptidyl-prolyl cis-trans isomerase-12 0.0053 0.0226 0.0259
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0059 0.0148
Loa Loa (eye worm) hypothetical protein 0.1459 0.8726 1
Brugia malayi nuclear receptor RXR 0.0102 0.0522 0.0598
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.0024 0.0047 0.0035
Loa Loa (eye worm) hypothetical protein 0.0091 0.0456 0.0522
Trypanosoma cruzi hypothetical protein, conserved 0.0075 0.0356 0.0397
Brugia malayi hypothetical protein 0.0102 0.0522 0.0598
Trypanosoma cruzi heat shock protein 90, putative 0.0039 0.0138 0.0147
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.0024 0.0047 0.0035
Entamoeba histolytica hypothetical protein 0.0143 0.0772 0.0867
Toxoplasma gondii Hsp90 domain-containing protein 0.0171 0.094 0.106

Activities

Activity type Activity value Assay description Source Reference
MISS T/C (functional) = 1.1 In vivo blood glucose was determined in obese, hyperglycemic, hyperinsulinemic, insulin-resistant KKAy mice after a dose of 500 mg/kg for 4 days ChEMBL. 11312922

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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