Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | coagulation factor X | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | prostaglandin f synthase, putative | 0.0067 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0067 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0067 | 1 | 1 |
Plasmodium vivax | oxidoreductase, aldo/keto reductase domain containing protein | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0067 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0067 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Mycobacterium ulcerans | oxidoreductase | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0067 | 1 | 1 |
Schistosoma mansoni | pol-related | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0047 | 0.5922 | 0.5922 |
Echinococcus granulosus | hypothetical protein | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Leishmania major | aldo-keto reductase-like protein | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0067 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 1 | 1 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 1 | 1 | |
Trypanosoma cruzi | aldo-keto reductase | 0.0067 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0067 | 1 | 0.5 |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Giardia lamblia | Aldose reductase | 0.0067 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldehyde reductase | 0.0047 | 0.5922 | 0.5922 |
Echinococcus multilocularis | aldo keto reductase | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Plasmodium falciparum | aldehyde reductase, putative | 0.0019 | 0 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0067 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldehyde reductase | 0.0047 | 0.5922 | 0.5922 |
Echinococcus granulosus | aldo keto reductase | 0.0067 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 1 | 1 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0067 | 1 | 1 |
Onchocerca volvulus | 0.0067 | 1 | 1 | |
Loa Loa (eye worm) | oxidoreductase | 0.0067 | 1 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0067 | 1 | 1 |
Plasmodium falciparum | aldo-keto reductase, putative | 0.0019 | 0 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Plasmodium vivax | aldehyde reductase, putative | 0.0019 | 0 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0067 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0067 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0067 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0067 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0067 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0067 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.