Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | hypothetical protein | 0.0179 | 0.0386 | 0.0386 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Brugia malayi | PXA domain containing protein | 0.002 | 0.0012 | 0.0012 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0016 | 0.0004 | 0.0259 |
Echinococcus granulosus | expressed conserved protein | 0.009 | 0.0177 | 0.0177 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0009 | 0.3663 |
Brugia malayi | steroid hormone receptor | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0155 | 0.033 | 0.033 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0212 | 0.0463 | 0.2774 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0004 | 0.0088 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0058 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0418 | 0.0946 | 0.0946 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0003 | 0.0154 |
Echinococcus granulosus | axis inhibition protein axin | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.0158 | 0.0158 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0122 | 0.0252 | 0.1499 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0106 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0002 | 0.0002 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0307 | 0.0685 | 0.4113 |
Loa Loa (eye worm) | hypothetical protein | 0.4278 | 1 | 1 |
Schistosoma mansoni | z-protein (S1r protein) | 0.002 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0122 | 0.0252 | 0.1499 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Echinococcus granulosus | 6 phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.002 | 0.0012 | 0.0012 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 0.0507 | 0.0507 |
Brugia malayi | hypoxia-induced factor 1 | 0.0155 | 0.033 | 0.033 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0003 | 0.0118 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0016 | 0.0002 | 0.0002 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0023 | 0.002 | 0.5642 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0044 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0106 | 0.0106 |
Brugia malayi | MAP kinase sur-1 | 0.006 | 0.0106 | 0.0106 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0152 | 0.0323 | 0.0323 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0105 | 0.0212 | 0.1263 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0105 | 0.0212 | 0.1263 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.002 | 0.0101 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.0102 | 0.0102 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1528 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0031 | 0.0031 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0058 | 0.0102 | 0.0102 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0723 | 0.1661 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.005 | 0.0083 | 0.0083 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.006 | 0.0106 | 0.0106 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.006 | 0.0106 | 0.4182 |
Brugia malayi | Carboxylesterase family protein | 0.0723 | 0.1661 | 0.1661 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0022 | 0.0017 | 0.0085 |
Brugia malayi | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0033 | 0.429 |
Onchocerca volvulus | 0.006 | 0.0106 | 0.0462 | |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.024 | 0.1429 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0122 | 0.0252 | 0.0252 |
Trichomonas vaginalis | glutaminase, putative | 0.0282 | 0.0628 | 0.3767 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0058 | 0.0101 | 0.0101 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0106 | 0.0106 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0003 | 0.0044 |
Plasmodium vivax | JmjC domain containing protein | 0.0016 | 0.0002 | 0.0138 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.006 | 0.0106 | 0.0106 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0017 | 0.0006 | 0.0006 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0591 | 0.1352 | 1 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0105 | 0.0212 | 0.1263 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | jumonji domain containing protein | 0.0058 | 0.0102 | 0.0102 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0106 | 0.0623 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.006 | 0.0106 | 0.4182 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0009 | 0.0009 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Brugia malayi | bHLH-PAS transcription factor | 0.0037 | 0.0053 | 0.0053 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0059 | 0.0059 |
Schistosoma mansoni | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Brugia malayi | ecdysteroid receptor | 0.0028 | 0.0031 | 0.0031 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0003 | 0.0052 |
Mycobacterium tuberculosis | Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) | 0.0106 | 0.0214 | 0.1275 |
Echinococcus multilocularis | expressed conserved protein | 0.009 | 0.0177 | 0.0177 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | putative regulatory protein | 0.0037 | 0.0053 | 0.03 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0028 | 0.0031 | 0.0031 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0074 | 0.3382 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0591 | 0.1352 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0212 | 0.0463 | 0.2774 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.002 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0009 | 0.0037 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0376 | 0.0376 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.002 | 0.0716 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0003 | 0.0003 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.0102 | 0.0102 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.002 | 0.0012 | 0.0054 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0122 | 0.0252 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 0.0507 | 0.0507 |
Mycobacterium leprae | PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) | 0.0106 | 0.0214 | 0.3123 |
Brugia malayi | PAS domain containing protein | 0.005 | 0.0083 | 0.0083 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0105 | 0.0212 | 0.3093 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0023 | 0.002 | 0.0101 |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.0158 | 0.0158 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0003 | 0.0052 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Echinococcus granulosus | expressed protein | 0.0385 | 0.087 | 0.087 |
Onchocerca volvulus | 0.0047 | 0.0076 | 0.0277 | |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0012 | 0.0054 |
Brugia malayi | jmjC domain containing protein | 0.0058 | 0.0102 | 0.0102 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0122 | 0.0252 | 0.0252 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.002 | 0.0012 | 0.0012 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0004 | 0.0088 |
Loa Loa (eye worm) | carboxylesterase | 0.0723 | 0.1661 | 0.1661 |
Entamoeba histolytica | pyrophosphate-dependent phosphofructokinase | 0.0029 | 0.0033 | 0.0176 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 1 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.002 | 0.0012 | 0.0012 |
Echinococcus multilocularis | neuroligin | 0.0723 | 0.1661 | 0.1661 |
Brugia malayi | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | nuclear hormone receptor | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0029 | 0.0033 | 0.022 |
Schistosoma mansoni | glutaminase | 0.0282 | 0.0628 | 0.0628 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0016 | 0.0002 | 0.0002 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0074 | 0.2931 |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0009 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0007 | 0.0007 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0037 | 0.0053 | 0.0053 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0289 | 0.0643 | 0.3858 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0191 | 0.0191 |
Schistosoma mansoni | hypothetical protein | 0.0175 | 0.0376 | 0.0376 |
Brugia malayi | Isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1528 |
Schistosoma mansoni | serine/threonine protein kinase | 0.002 | 0.0013 | 0.0013 |
Brugia malayi | glutaminase DH11.1 | 0.0282 | 0.0628 | 0.0628 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0009 | 0.0037 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0058 | 0.0102 | 0.0102 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0074 | 0.6935 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1275 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.002 | 0.0012 | 0.0012 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0033 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.006 | 0.0106 | 0.4915 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.0194 | 0.0194 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0031 | 0.0031 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0003 | 0.0118 |
Schistosoma mansoni | regulator of G protein signaling | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0723 | 0.1661 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | axis inhibition protein axin | 0.002 | 0.0012 | 0.0012 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0016 | 0.0004 | 0.0004 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.0258 | 0.0258 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.0031 | 0.0031 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.024 | 0.3535 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0307 | 0.0685 | 0.4113 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0307 | 0.0685 | 0.4113 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Schistosoma mansoni | regulator of G protein signaling | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.002 | 0.0012 | 0.0012 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.002 | 0.0841 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.4278 | 1 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.006 | 0.0106 | 0.0106 |
Onchocerca volvulus | 0.0723 | 0.1661 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.006 | 0.0106 | 0.0106 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0002 | 0.0002 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0003 | 0.0154 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0009 | 0.0009 |
Schistosoma mansoni | serine/threonine protein kinase | 0.002 | 0.0013 | 0.0013 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0289 | 0.0643 | 1 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0062 | 0.0062 |
Loa Loa (eye worm) | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Entamoeba histolytica | hypothetical protein | 0.002 | 0.0012 | 0.0021 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0074 | 0.0427 |
Onchocerca volvulus | 0.0037 | 0.0053 | 0.0135 | |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Brugia malayi | Carboxylesterase family protein | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0028 | 0.0031 | 0.0031 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0009 | 0.0046 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 0.0507 | 0.0507 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0307 | 0.0685 | 0.0685 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0201 | 0.0438 | 0.2495 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.002 | 0.0785 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0307 | 0.0685 | 0.4113 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0001 | 0.0001 |
Echinococcus multilocularis | carboxylesterase 5A | 0.4278 | 1 | 1 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | mitogen activated protein kinase | 0.006 | 0.0106 | 0.0106 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0028 | 0.0031 | 0.0031 |
Trypanosoma brucei | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0106 | 0.0214 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0076 | 0.0076 |
Schistosoma mansoni | nuclear hormone receptor | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.0158 | 0.0158 |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0074 | 0.0074 |
Echinococcus granulosus | carboxylesterase 5A | 0.4278 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.4278 | 1 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.006 | 0.0106 | 0.4915 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Plasmodium vivax | SET domain protein, putative | 0.006 | 0.0106 | 1 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0016 | 0.0002 | 0.0002 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1275 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0105 | 0.0212 | 0.1263 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0012 | 0.0054 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0002 | 0.0002 |
Giardia lamblia | Kinase, CMGC MAPK | 0.006 | 0.0106 | 0.0766 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.0031 | 0.0031 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0016 | 0.0002 | 0.0074 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 0.0323 | 0.0323 |
Chlamydia trachomatis | fructose-6-phosphate phosphotransferase | 0.0029 | 0.0033 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | gliotactin | 0.0723 | 0.1661 | 0.1661 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | bloom syndrome protein | 0.0022 | 0.0017 | 0.0017 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Echinococcus multilocularis | acetylcholinesterase | 0.4278 | 1 | 1 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0003 | 0.0154 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.002 | 0.0013 | 0.0013 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0016 | 0.0004 | 0.0088 |
Echinococcus granulosus | acetylcholinesterase | 0.4278 | 1 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0282 | 0.0628 | 0.0628 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0074 | 0.0074 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0009 | 0.0037 |
Mycobacterium ulcerans | glutaminase | 0.0282 | 0.0628 | 0.3767 |
Echinococcus multilocularis | phd:f box containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Echinococcus multilocularis | lamin | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0091 | 0.0091 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0009 | 0.0341 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0016 | 0.0002 | 0.0002 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0003 | 0.0243 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0003 | 0.0154 |
Schistosoma mansoni | regulator of G protein signaling | 0.002 | 0.0012 | 0.0012 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0148 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0074 | 0.3382 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.002 | 0.0012 | 0.0012 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 1 |
Loa Loa (eye worm) | RecQ helicase | 0.0022 | 0.0017 | 0.0017 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0003 | 0.0003 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.002 | 0.0012 | 0.0012 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0009 | 0.0009 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0723 | 0.1661 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0074 | 0.0074 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0723 | 0.1661 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0001 | 0.0001 |
Brugia malayi | nuclear receptor NHR-88 | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.006 | 0.0106 | 0.0106 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0106 | 0.0623 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0074 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.006 | 0.0106 | 0.4915 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0191 | 0.1354 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0058 | 0.0102 | 0.0102 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.002 | 0.0013 | 0.0013 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0016 | 0.0002 | 0.0002 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0044 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.002 | 0.0012 | 0.0012 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0016 | 0.0004 | 0.0314 |
Onchocerca volvulus | 0.0723 | 0.1661 | 1 | |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0062 | 0.0062 |
Schistosoma mansoni | acetylcholinesterase | 0.0723 | 0.1661 | 0.1661 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0076 | 0.0076 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.002 | 0.2488 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | protein phosphatase 2C | 0.0016 | 0.0002 | 0.0002 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0023 | 0.002 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0723 | 0.1661 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0028 | 0.0031 | 0.0031 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.002 | 0.0013 | 0.0013 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0074 | 0.0074 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | phd/f-box containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0137 | 0.0288 | 0.0288 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.006 | 0.0106 | 0.0106 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.002 | 0.0079 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0016 | 0.0004 | 0.0088 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0003 | 0.0044 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0028 | 0.0031 | 0.0031 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0033 | 0.3054 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0059 | 0.0059 |
Onchocerca volvulus | 0.0723 | 0.1661 | 1 | |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.024 | 0.1429 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | axis inhibition protein axin | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Echinococcus granulosus | FTZ F1 alpha | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0031 | 0.0031 |
Plasmodium falciparum | ATP-dependent 6-phosphofructokinase | 0.0029 | 0.0033 | 0.429 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Schistosoma mansoni | single-minded | 0.005 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.0158 | 0.0158 |
Echinococcus granulosus | bloom syndrome protein | 0.0022 | 0.0017 | 0.0017 |
Onchocerca volvulus | 0.0179 | 0.0386 | 0.2182 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0012 | 0.0054 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0028 | 0.0031 | 0.0031 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0016 | 0.0002 | 0.0074 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.006 | 0.0106 | 0.4226 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus multilocularis | musashi | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | CMGC family protein kinase | 0.006 | 0.0106 | 0.0623 |
Schistosoma mansoni | lamin | 0.0028 | 0.0031 | 0.0031 |
Entamoeba histolytica | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1528 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0361 | 0.0361 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0062 | 0.0062 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0258 | 0.0258 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.0258 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | Pre-SET motif family protein | 0.006 | 0.0106 | 0.0106 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0016 | 0.0002 | 0.0002 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.031 | 0.0692 | 0.0692 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0074 | 0.2878 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0106 | 0.0106 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0003 | 0.0052 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0059 | 0.0059 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0122 | 0.0252 | 0.1499 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.006 | 0.0106 | 0.4915 |
Loa Loa (eye worm) | hypothetical protein | 0.4278 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.4278 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0028 | 0.0031 | 0.0031 |
Treponema pallidum | diphosphate--fructose-6-phosphate 1-phosphotransferase | 0.0106 | 0.0214 | 0.1567 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0016 | 0.0002 | 0.0002 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.0009 | 0.0046 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0003 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0084 | 0.0084 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0062 | 0.0062 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0009 | 0.0009 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0016 | 0.0004 | 0.0075 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.006 | 0.0106 | 0.4915 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0723 | 0.1661 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0307 | 0.0685 | 0.4113 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0012 | 0.0054 |
Onchocerca volvulus | 0.0082 | 0.0158 | 0.0783 | |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0191 | 0.0191 |
Schistosoma mansoni | coup transcription factor | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Echinococcus multilocularis | 6 phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Schistosoma mansoni | regulator of G protein signaling | 0.002 | 0.0012 | 0.0012 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0074 | 0.0074 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0022 | 0.0017 | 0.0017 |
Schistosoma mansoni | thyroid hormone receptor | 0.0152 | 0.0323 | 0.0323 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1275 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0723 | 0.1661 | 0.1661 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.002 | 0.0013 | 0.0013 |
Trichomonas vaginalis | 6-phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Toxoplasma gondii | phosphofructokinase domain-containing protein | 0.0029 | 0.0033 | 0.13 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0023 | 0.002 | 0.0101 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0062 | 0.0062 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Mycobacterium ulcerans | 6-phosphofructokinase | 0.0106 | 0.0214 | 0.1275 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0016 | 0.0002 | 0.0002 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0438 | 0.2621 |
Echinococcus granulosus | lamin | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | hypothetical protein | 0.0169 | 0.0361 | 0.0361 |
Brugia malayi | hypothetical protein | 0.0231 | 0.0507 | 0.0507 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0029 | 0.0033 | 0.0179 |
Mycobacterium tuberculosis | Probable reductase | 0.0105 | 0.0212 | 0.1263 |
Brugia malayi | Carboxylesterase family protein | 0.0723 | 0.1661 | 0.1661 |
Brugia malayi | PXA domain containing protein | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | axis inhibition protein axin | 0.002 | 0.0012 | 0.0012 |
Toxoplasma gondii | phosphofructokinase PFKII | 0.0029 | 0.0033 | 0.13 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.002 | 0.0013 | 0.0013 |
Schistosoma mansoni | lamin | 0.0028 | 0.0031 | 0.0031 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0074 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0723 | 0.1661 | 0.1661 |
Giardia lamblia | Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit | 0.0029 | 0.0033 | 0.022 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.006 | 0.0106 | 0.0106 |
Toxoplasma gondii | 6-phosphofructokinase | 0.0029 | 0.0033 | 0.13 |
Brugia malayi | Carboxylesterase family protein | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | serine/threonine protein kinase | 0.002 | 0.0013 | 0.0013 |
Brugia malayi | phosphofructokinase | 0.0106 | 0.0214 | 0.0214 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.002 | 0.0012 | 0.0012 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0122 | 0.0252 | 0.1499 |
Loa Loa (eye worm) | carboxylesterase | 0.4278 | 1 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0009 | 0.0824 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0591 | 0.1352 | 0.8135 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0009 | 0.0341 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0028 | 0.0031 | 0.0031 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0003 | 0.0052 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0723 | 0.1661 | 0.1661 |
Leishmania major | ATP-dependent phosphofructokinase | 0.0106 | 0.0214 | 0.8509 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.006 | 0.0106 | 0.0106 |
Entamoeba histolytica | hypothetical protein | 0.002 | 0.0012 | 0.0021 |
Trichomonas vaginalis | phosphofructokinase, putative | 0.0106 | 0.0214 | 0.1275 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0122 | 0.0252 | 0.0252 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0028 | 0.0031 | 0.0031 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0028 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0003 | 0.0003 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0062 | 0.0357 |
Trypanosoma cruzi | ATP-dependent 6-phosphofructokinase, glycosomal | 0.0106 | 0.0214 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0003 | 0.0052 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.0009 | 0.0363 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0012 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0031 | 0.0031 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.0009 | 0.029 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0009 | 0.0009 |
Echinococcus granulosus | single minded 2 | 0.0037 | 0.0053 | 0.0053 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0289 | 0.0643 | 0.3858 |
Trichomonas vaginalis | set domain proteins, putative | 0.0476 | 0.1081 | 0.6504 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0028 | 0.0031 | 0.0031 |
Plasmodium vivax | 6-phosphofructokinase, putative | 0.0029 | 0.0033 | 0.3054 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.003 | 0.003 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0009 | 0.1009 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.0386 | 0.0386 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 0.0011 | 0.1253 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.002 | 0.0012 | 0.0012 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0122 | 0.0252 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0058 | 0.0102 | 0.0102 |
Brugia malayi | Pre-SET motif family protein | 0.0418 | 0.0946 | 0.0946 |
Entamoeba histolytica | hypothetical protein | 0.002 | 0.0012 | 0.0021 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0022 | 0.0017 | 0.0085 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0105 | 0.0212 | 0.1263 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.024 | 0.1429 |
Brugia malayi | hypothetical protein | 0.002 | 0.0012 | 0.0012 |
Schistosoma mansoni | regulator of G protein signaling | 0.002 | 0.0012 | 0.0012 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.006 | 0.0106 | 0.4218 |
Echinococcus multilocularis | geminin | 0.0175 | 0.0376 | 0.0376 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0016 | 0.0004 | 0.0005 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0076 | 0.0076 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0023 | 0.002 | 0.0124 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0062 | 0.0062 |
Echinococcus multilocularis | axis inhibition protein axin | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0062 | 0.0062 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.002 | 0.0785 |
Echinococcus multilocularis | regulator of G protein signaling | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0062 | 0.0062 |
Echinococcus granulosus | geminin | 0.0175 | 0.0376 | 0.0376 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0307 | 0.0685 | 0.0685 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.002 | 0.0012 | 0.0012 |
Brugia malayi | hypothetical protein | 0.0119 | 0.0244 | 0.0244 |
Schistosoma mansoni | axis inhibition protein axin | 0.002 | 0.0012 | 0.0012 |
Echinococcus granulosus | phd:f box containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.002 | 0.0012 | 0.0012 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0148 |
Brugia malayi | jmjC domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0028 | 0.0031 | 0.0031 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0307 | 0.0685 | 0.4113 |
Loa Loa (eye worm) | RGS-3 protein | 0.002 | 0.0012 | 0.0012 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0003 | 0.0052 |
Echinococcus granulosus | neuroligin | 0.0723 | 0.1661 | 0.1661 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0074 | 0.0074 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.006 | 0.0106 | 0.0106 |
Trypanosoma brucei | protein kinase, putative | 0.006 | 0.0106 | 0.4915 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0963 | 0.2224 | 0.2224 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0028 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0028 | 0.0031 | 0.0031 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0016 | 0.0002 | 0.0002 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0074 | 0.6935 |
Onchocerca volvulus | 0.0723 | 0.1661 | 1 | |
Loa Loa (eye worm) | glutaminase | 0.0282 | 0.0628 | 0.0628 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0016 | 0.0004 | 0.0004 |
Echinococcus multilocularis | expressed protein | 0.0385 | 0.087 | 0.087 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.006 | 0.0106 | 0.0106 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0028 | 0.0031 | 0.0031 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0076 | 0.0076 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0122 | 0.0252 | 0.0252 |
Onchocerca volvulus | 0.0476 | 0.1081 | 0.6445 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.002 | 0.0012 | 0.0054 |
Loa Loa (eye worm) | carboxylesterase | 0.0723 | 0.1661 | 0.1661 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0009 | 0.0341 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0028 | 0.0031 | 0.0031 |
Echinococcus granulosus | acetylcholinesterase | 0.4278 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | jumonji domain containing protein | 0.0016 | 0.0002 | 0.0002 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.4278 | 1 | 1 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.002 | 0.1829 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0137 | 0.0288 | 0.0288 |
Onchocerca volvulus | 0.0723 | 0.1661 | 1 | |
Schistosoma mansoni | phosphatidylserine receptor | 0.0016 | 0.0002 | 0.0002 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.002 | 0.0012 | 0.0012 |
Loa Loa (eye worm) | hypothetical protein | 0.0723 | 0.1661 | 0.1661 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0009 | 0.0009 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 22 % | Tested for agonist activity through assays of phosphoinositide (PI) metabolism in slices from rat cerebral cortex | ChEMBL. | 9111297 |
IC50 (binding) | = 43 uM | Inhibition of specific [3H]-(R)-QNB binding to Muscarinic acetylcholine receptor in rat brain membranes | ChEMBL. | 9111297 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.