Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | carboxylesterase 5A | 0.0294 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0294 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0294 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.005 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0294 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.005 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0294 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.005 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0294 | 1 | 1 |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0294 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.005 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0294 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.005 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0294 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0294 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0294 | 1 | 1 |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Onchocerca volvulus | 0.005 | 0 | 0.5 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.005 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0294 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.