Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | cathepsin L-like precursor | 0.0615 | 0.6642 | 0.6642 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0615 | 0.6642 | 0.6595 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0169 | 0.1716 | 0.1716 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0169 | 0.1716 | 0.1621 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0169 | 0.1716 | 0.5 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0169 | 0.1716 | 0.1716 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0161 | 0.0024 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0234 | 0.0234 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0234 | 0.0122 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0615 | 0.6642 | 0.6561 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0035 | 0.0234 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0918 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0234 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0169 | 0.1716 | 0.1601 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0473 | 0.5074 | 0.5074 |
Echinococcus granulosus | cathepsin L | 0.0473 | 0.5074 | 0.5006 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0149 | 0.0012 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0169 | 0.1716 | 0.1621 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0169 | 0.1716 | 0.1621 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0169 | 0.1716 | 0.1621 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0918 | 1 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0169 | 0.1716 | 0.1621 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0615 | 0.6642 | 0.6595 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Onchocerca volvulus | 0.0169 | 0.1716 | 0.1601 | |
Plasmodium vivax | unspecified product | 0.0169 | 0.1716 | 0.1621 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0234 | 0.0098 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0331 | 0.0196 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0358 | 0.0358 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0234 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Echinococcus granulosus | cathepsin b | 0.0169 | 0.1716 | 0.1601 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0169 | 0.1716 | 0.1716 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0201 | 0.207 | 0.207 |
Onchocerca volvulus | 0.0029 | 0.0161 | 0.0024 | |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Onchocerca volvulus | 0.0229 | 0.2378 | 0.2272 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0169 | 0.1716 | 0.1716 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0169 | 0.1716 | 0.1621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Giardia lamblia | Hypothetical protein | 0.0169 | 0.1716 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0331 | 0.0196 |
Onchocerca volvulus | 0.0615 | 0.6642 | 0.6595 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0169 | 0.1716 | 0.1621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Giardia lamblia | Cathepsin L precursor | 0.0169 | 0.1716 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0234 | 0.0122 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0473 | 0.5074 | 0.5018 |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0918 | 1 | 1 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0358 | 0.0224 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0169 | 0.1716 | 0.1621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0473 | 0.5074 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Plasmodium vivax | vivapain-1 | 0.0473 | 0.5074 | 0.5018 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0169 | 0.1716 | 0.1716 |
Onchocerca volvulus | Cathepsin L homolog | 0.0918 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0918 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0169 | 0.1716 | 0.1601 |
Loa Loa (eye worm) | hypothetical protein | 0.0615 | 0.6642 | 0.6642 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0169 | 0.1716 | 0.1621 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0473 | 0.5074 | 0.5018 |
Onchocerca volvulus | 0.0035 | 0.0234 | 0.0098 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0473 | 0.5074 | 0.5006 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Brugia malayi | Cathepsin L-like precursor | 0.0615 | 0.6642 | 0.6642 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0229 | 0.2374 | 0.2267 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0234 | 0.0234 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Giardia lamblia | Cathepsin L precursor | 0.0169 | 0.1716 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.32 | 0.32 |
Trypanosoma cruzi | cysteine protease, putative | 0.0473 | 0.5074 | 0.5018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0473 | 0.5074 | 0.4956 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0169 | 0.1716 | 0.1716 |
Echinococcus granulosus | cysteine protease | 0.0473 | 0.5074 | 0.5006 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0169 | 0.1716 | 0.1716 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0918 | 1 | 1 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0161 | 0.0024 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0169 | 0.1716 | 0.1518 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0304 | 0.32 | 0.3122 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0169 | 0.1716 | 0.1621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0918 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0169 | 0.1716 | 0.1621 |
Brugia malayi | Pre-SET motif family protein | 0.0201 | 0.207 | 0.207 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0169 | 0.1716 | 0.1621 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0169 | 0.1716 | 0.1621 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0304 | 0.32 | 0.32 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0918 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0161 | 0.0024 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0169 | 0.1716 | 0.1716 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0169 | 0.1716 | 0.1716 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0473 | 0.5074 | 0.4956 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0473 | 0.5074 | 0.4054 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0161 | 0.0024 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0169 | 0.1716 | 0.1621 |
Brugia malayi | cathepsin L precursor | 0.0169 | 0.1716 | 0.1716 |
Loa Loa (eye worm) | hypothetical protein | 0.0615 | 0.6642 | 0.6642 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0234 | 0.0098 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Toxoplasma gondii | cathepsin CPC1 | 0.0169 | 0.1716 | 0.1621 |
Echinococcus granulosus | cathepsin b | 0.0169 | 0.1716 | 0.1601 |
Giardia lamblia | Cathepsin L precursor | 0.0169 | 0.1716 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0169 | 0.1716 | 0.5 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0017 | 0.0017 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Brugia malayi | Cathepsin L-like precursor | 0.0304 | 0.32 | 0.32 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0161 | 0.0024 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0161 | 0.0049 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0137 | 0.0137 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0169 | 0.1716 | 0.1621 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Giardia lamblia | Encystation-specific protease | 0.0169 | 0.1716 | 0.5 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0473 | 0.5074 | 0.5006 |
Schistosoma mansoni | cathepsin C | 0.0169 | 0.1716 | 0.1601 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0473 | 0.5074 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0918 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0304 | 0.32 | 0.3122 |
Echinococcus multilocularis | cathepsin L | 0.0473 | 0.5074 | 0.5006 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Giardia lamblia | Cysteine protease | 0.0169 | 0.1716 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0234 | 0.0122 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0113 | 0.0113 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0137 | 0.0137 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1716 | 0.1716 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0169 | 0.1716 | 0.1621 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0358 | 0.0224 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0169 | 0.1716 | 0.1621 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0227 | 0.2349 | 1 |
Onchocerca volvulus | 0.0035 | 0.0234 | 0.0098 | |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0234 | 0.0234 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0473 | 0.5074 | 0.5018 |
Brugia malayi | Cathepsin L-like precursor | 0.0918 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0169 | 0.1716 | 0.1621 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1716 | 0.1716 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0234 | 0.0234 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Brugia malayi | Cathepsin L-like precursor | 0.0615 | 0.6642 | 0.6642 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0137 | 0.0137 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0169 | 0.1716 | 0.1621 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0615 | 0.6642 | 0.6603 |
Echinococcus multilocularis | cysteine protease | 0.0918 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0331 | 0.0196 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0137 | 0.0137 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0169 | 0.1716 | 0.1716 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0234 | 0.0122 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0918 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0331 | 0.0331 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0473 | 0.5074 | 0.5018 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.32 | 0.32 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0169 | 0.1716 | 0.1621 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0473 | 0.5074 | 0.5006 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0137 | 0.0137 |
Onchocerca volvulus | 0.0035 | 0.0234 | 0.0098 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0234 | 0.0234 |
Plasmodium vivax | vivapain-2 | 0.0918 | 1 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0161 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0234 | 0.0234 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0473 | 0.5074 | 0.5018 |
Trichomonas vaginalis | set domain proteins, putative | 0.0229 | 0.2378 | 0.2195 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0331 | 0.0196 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0169 | 0.1716 | 0.1621 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0473 | 0.5074 | 0.5074 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0234 | 0.0098 |
Echinococcus granulosus | cathepsin l1 | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0234 | 0.0234 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0169 | 0.1716 | 0.1621 |
Giardia lamblia | Cathepsin L-like protease | 0.0169 | 0.1716 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0473 | 0.5074 | 0.5018 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0331 | 0.0196 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0169 | 0.1716 | 0.1621 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0304 | 0.32 | 0.32 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Giardia lamblia | Cathepsin L precursor | 0.0169 | 0.1716 | 0.5 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0169 | 0.1716 | 0.1621 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0169 | 0.1716 | 0.1621 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0169 | 0.1716 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0234 | 0.0234 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1716 | 0.1716 |
Plasmodium vivax | vivapain-3 | 0.0473 | 0.5074 | 0.5018 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0234 | 0.5 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0615 | 0.6642 | 0.6642 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Giardia lamblia | Cathepsin L-like protease | 0.0169 | 0.1716 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0169 | 0.1716 | 0.1621 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0161 | 0.0024 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0918 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0918 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0169 | 0.1716 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0229 | 0.2374 | 0.2374 |
Giardia lamblia | Cysteine protease | 0.0169 | 0.1716 | 0.5 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0234 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0918 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Plasmodium vivax | unspecified product | 0.0473 | 0.5074 | 0.5018 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0799 | 0.8681 | 0.8663 |
Leishmania major | cysteine peptidase A (CPA) | 0.0918 | 1 | 1 |
Giardia lamblia | Cysteine protease | 0.0169 | 0.1716 | 0.5 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0169 | 0.1716 | 0.1621 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0615 | 0.6642 | 0.6561 |
Toxoplasma gondii | cathepsin CPC2 | 0.0169 | 0.1716 | 0.1621 |
Loa Loa (eye worm) | hypothetical protein | 0.0615 | 0.6642 | 0.6642 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0304 | 0.32 | 0.32 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0234 | 0.0234 |
Toxoplasma gondii | cathepsin CPL | 0.0918 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0234 | 0.0234 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0473 | 0.5074 | 0.4054 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0234 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0169 | 0.1716 | 0.1601 |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0918 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0918 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0918 | 1 | 1 |
Giardia lamblia | Hypothetical protein | 0.0169 | 0.1716 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0169 | 0.1716 | 0.5 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0918 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0473 | 0.5074 | 0.4054 |
Onchocerca volvulus | Cathepsin L homolog | 0.0918 | 1 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0234 | 0.0234 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0169 | 0.1716 | 0.1621 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0331 | 0.0196 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0331 | 0.0331 |
Giardia lamblia | Cysteine protease | 0.0169 | 0.1716 | 0.5 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0169 | 0.1716 | 0.1621 |
Plasmodium vivax | vivapain-2 | 0.0918 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0473 | 0.5074 | 0.5006 |
Brugia malayi | Cathepsin L-like precursor | 0.0918 | 1 | 1 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0169 | 0.1716 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0234 | 0.0122 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0331 | 0.0196 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0161 | 0.0161 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0113 | 0.0113 |
Brugia malayi | Cathepsin L-like precursor | 0.0918 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0169 | 0.1716 | 0.1518 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0229 | 0.2374 | 0.2267 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0304 | 0.32 | 0.3122 |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0169 | 0.1716 | 0.1601 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0161 | 0.0161 |
Echinococcus multilocularis | cathepsin L | 0.0169 | 0.1716 | 0.1601 |
Mycobacterium leprae | Probable lipase LipE | 0.0035 | 0.0234 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0234 | 0.0122 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0169 | 0.1716 | 0.1518 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0918 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0473 | 0.5074 | 0.5018 |
Onchocerca volvulus | 0.0047 | 0.0358 | 0.0224 | |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 0.32 | 0.32 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0169 | 0.1716 | 0.1621 |
Brugia malayi | fibroinase precursor | 0.0169 | 0.1716 | 0.1716 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0918 | 1 | 1 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Echinococcus multilocularis | cysteine protease | 0.0918 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0615 | 0.6642 | 0.5946 |
Loa Loa (eye worm) | ctsf protein | 0.0918 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0169 | 0.1716 | 0.1621 |
Leishmania major | cathepsin L-like protease | 0.0918 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0234 | 0.0234 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0234 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0918 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0169 | 0.1716 | 0.5 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0132 | 0.0132 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0161 | 0.0049 |
Schistosoma mansoni | cathepsin s | 0.0304 | 0.32 | 0.3105 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0169 | 0.1716 | 0.1601 |
Entamoeba histolytica | cysteine protease, putative | 0.0473 | 0.5074 | 0.4054 |
Loa Loa (eye worm) | fibroinase | 0.0918 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0169 | 0.1716 | 0.1621 |
Brugia malayi | hypothetical protein | 0.0229 | 0.2374 | 0.2374 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0473 | 0.5074 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0918 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0918 | 1 | 1 |
Onchocerca volvulus | 0.0918 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.1716 | 0.1716 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.246 uM | Antagonistic activity against tritiated agonist (SFFLRR-NH2, at 25 nM) binding to human platelet membranes measured by the GTPase assay | ChEMBL. | 8960546 |
IC50 (functional) | = 5 uM | Concentration required to inhibit agonist (SFFLRR-NH2, at 3 uM) induced platelet aggregation by 50% | ChEMBL. | 8960546 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.