Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin b | 0.0134 | 1 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0134 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0134 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0134 | 1 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0134 | 1 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0044 | 0 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0044 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0134 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0134 | 1 | 0.5 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0134 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0134 | 1 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.