Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0046 | 0.0541 | 0.0548 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0032 | 0.0324 | 0.0324 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.005 | 0.06 | 0.0607 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.006 | 0.0744 | 0.0744 |
Echinococcus granulosus | FTZ F1 alpha | 0.0046 | 0.0541 | 0.0548 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0046 | 0.0541 | 0.0541 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0046 | 0.0541 | 0.0548 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0116 | 0.0116 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Brugia malayi | nuclear receptor RXR | 0.0025 | 0.0212 | 0.0212 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0032 | 0.0324 | 0.0324 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0999 | 0.0999 |
Schistosoma mansoni | nuclear hormone receptor | 0.0046 | 0.0541 | 0.0541 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0138 | 0.1919 | 0.1919 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0395 | 0.5791 | 0.5862 |
Mycobacterium ulcerans | putative regulatory protein | 0.0071 | 0.0907 | 0.0907 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0046 | 0.0541 | 0.0541 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0046 | 0.0541 | 0.0548 |
Echinococcus granulosus | cpg binding protein | 0.0029 | 0.0284 | 0.0288 |
Schistosoma mansoni | lipoxygenase | 0.0019 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.06 | 0.1216 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.005 | 0.06 | 0.06 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.038 | 0.038 |
Leishmania major | protein kinase, putative | 0.0025 | 0.0223 | 0.0223 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0046 | 0.0541 | 0.0548 |
Schistosoma mansoni | aryl hydrocarbon receptor | 0.0096 | 0.1281 | 0.1281 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0282 | 0.4093 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0046 | 0.0541 | 0.1159 |
Mycobacterium leprae | Possible regulatory protein | 0.0025 | 0.0217 | 0.0217 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0022 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0046 | 0.0541 | 0.1159 |
Brugia malayi | hypothetical protein | 0.0228 | 0.3282 | 0.3282 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0025 | 0.0217 | 0.0252 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0217 | 0.0252 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0212 | 0.0453 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0228 | 0.3282 | 0.3322 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0116 | 0.0249 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0022 | 0.0172 | 0.0174 |
Brugia malayi | Inositol-1 | 0.0036 | 0.038 | 0.038 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0046 | 0.0541 | 0.0548 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0022 | 0.0172 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0046 | 0.0541 | 0.0548 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0046 | 0.0541 | 0.0548 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0116 | 0.0116 |
Schistosoma mansoni | thyroid hormone receptor | 0.0046 | 0.0541 | 0.0541 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0116 | 0.0118 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0046 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0217 | 0.0252 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0046 | 0.0541 | 0.1159 |
Brugia malayi | MAP kinase sur-1 | 0.005 | 0.06 | 0.06 |
Brugia malayi | bZIP transcription factor family protein | 0.0086 | 0.113 | 0.113 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0022 | 0.0172 | 0.0369 |
Chlamydia trachomatis | two component regulatory system sensor histidine kinase | 0.0025 | 0.0217 | 0.5 |
Echinococcus granulosus | tumor protein p63 | 0.0326 | 0.4757 | 0.4815 |
Trichomonas vaginalis | guanylate cyclase, putative | 0.0025 | 0.0217 | 0.0252 |
Trypanosoma brucei | protein kinase, putative | 0.005 | 0.06 | 0.06 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.005 | 0.06 | 0.06 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0133 | 0.0135 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0046 | 0.0541 | 0.0541 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0025 | 0.0217 | 0.0217 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0046 | 0.0541 | 0.1159 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0046 | 0.0541 | 0.0548 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0133 | 0.0133 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0133 | 0.0133 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.038 | 0.0663 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0025 | 0.0223 | 0.0223 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0022 | 0.0172 | 0.0172 |
Echinococcus granulosus | jun protein | 0.0086 | 0.113 | 0.1144 |
Onchocerca volvulus | 0.0028 | 0.026 | 0.1646 | |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0999 | 0.222 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0022 | 0.0172 | 0.0506 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0025 | 0.0217 | 0.0252 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.063 | 0.135 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0116 | 0.0116 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.005 | 0.06 | 0.1285 |
Brugia malayi | steroid hormone receptor | 0.0046 | 0.0541 | 0.0541 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0025 | 0.0217 | 0.0252 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0019 | 0.0133 | 0.0017 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0025 | 0.0212 | 0.0212 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0036 | 0.038 | 0.0385 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0019 | 0.0133 | 0.0135 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0675 | 1 | 1 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0675 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.038 | 0.038 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0284 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0212 | 0.0212 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0022 | 0.0172 | 0.0174 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0046 | 0.0541 | 0.5268 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0022 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0321 | 0.4669 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.038 | 0.038 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0116 | 0.0118 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0133 | 0.0133 |
Echinococcus multilocularis | cpg binding protein | 0.0029 | 0.0284 | 0.0288 |
Loa Loa (eye worm) | hypoxia-induced factor 1 | 0.0296 | 0.4295 | 0.9199 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0046 | 0.0541 | 0.0541 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0138 | 0.1919 | 0.1919 |
Loa Loa (eye worm) | DR-78 | 0.0022 | 0.0172 | 0.0369 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Schistosoma mansoni | thyroid hormone receptor | 0.0046 | 0.0541 | 0.0541 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.006 | 0.0744 | 0.0753 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0562 | 0.1204 |
Brugia malayi | Cytochrome P450 family protein | 0.0048 | 0.0564 | 0.0564 |
Giardia lamblia | Kinase, CMGC MAPK | 0.005 | 0.06 | 0.1216 |
Brugia malayi | PAS domain containing protein | 0.0096 | 0.1281 | 0.1281 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0667 | 0.9878 | 0.9878 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0046 | 0.0541 | 0.0541 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0217 | 0.0464 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0046 | 0.0541 | 0.0541 |
Schistosoma mansoni | nuclear receptor | 0.0022 | 0.0172 | 0.0172 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0212 | 0.0212 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0022 | 0.0172 | 0.0174 |
Onchocerca volvulus | 0.0048 | 0.0562 | 0.554 | |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0022 | 0.0172 | 0.0369 |
Brugia malayi | hypoxia-induced factor 1 | 0.0296 | 0.4295 | 0.4295 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0036 | 0.038 | 0.0267 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0022 | 0.0172 | 0.0172 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0022 | 0.0172 | 0.0174 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0263 | 0.3809 | 0.3856 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.0729 | 0.0729 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0046 | 0.0541 | 0.0541 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0025 | 0.0217 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0133 | 0.0285 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0046 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0054 | 0.0655 | 0.0663 |
Schistosoma mansoni | single-minded | 0.0096 | 0.1281 | 0.1281 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0284 | 0.0284 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0046 | 0.0541 | 0.0541 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0046 | 0.0541 | 0.5268 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0036 | 0.038 | 0.038 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0059 | 0.0736 | 0.0745 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.005 | 0.06 | 0.06 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0212 | 0.0453 |
Brugia malayi | tailless protein | 0.0022 | 0.0172 | 0.0172 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0036 | 0.038 | 0.0663 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0046 | 0.0541 | 0.0548 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0077 | 0.0999 | 0.1011 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0046 | 0.0541 | 0.0541 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0086 | 0.113 | 0.1144 |
Leishmania major | PAS-domain containing phosphoglycerate kinase, putative | 0.0025 | 0.0217 | 0.0217 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0263 | 0.3809 | 0.3856 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0562 | 0.0562 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0046 | 0.0541 | 0.0541 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.06 | 0.1216 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0077 | 0.0999 | 0.0999 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0046 | 0.0541 | 0.0541 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0675 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0022 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0036 | 0.038 | 0.0663 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.005 | 0.06 | 0.06 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.006 | 0.0744 | 0.0744 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0022 | 0.0172 | 0.0172 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0022 | 0.0172 | 0.0174 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0228 | 0.3282 | 0.3322 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0116 | 0.0116 |
Schistosoma mansoni | coup transcription factor | 0.0046 | 0.0541 | 0.0541 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0025 | 0.0212 | 0.0214 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0022 | 0.0172 | 0.0172 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0059 | 0.0736 | 0.0745 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0046 | 0.0541 | 0.0541 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0046 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0046 | 0.0541 | 0.1159 |
Brugia malayi | nuclear receptor NHR-67 | 0.0022 | 0.0172 | 0.0172 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0046 | 0.0541 | 0.0541 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0133 | 0.0135 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0046 | 0.0541 | 0.0548 |
Echinococcus granulosus | mitogen activated protein kinase | 0.005 | 0.06 | 0.0607 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0036 | 0.038 | 0.0385 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0046 | 0.0541 | 0.0541 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0036 | 0.038 | 0.038 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0212 | 0.0453 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0675 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0999 | 0.0999 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0046 | 0.0541 | 0.0548 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0046 | 0.0541 | 0.0548 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0022 | 0.0172 | 0.0174 |
Brugia malayi | nuclear hormone receptor | 0.0022 | 0.0172 | 0.0172 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0036 | 0.038 | 0.0663 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0116 | 0.0116 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0022 | 0.0172 | 0.0172 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | aryl Hydrocarbon receptor Associated protein family member | 0.0025 | 0.0217 | 0.0464 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0263 | 0.3809 | 0.3856 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0999 | 0.222 |
Brugia malayi | hypothetical protein | 0.0067 | 0.0853 | 0.0853 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.005 | 0.06 | 0.06 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.026 | 0.026 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0172 | 0.0172 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Onchocerca volvulus | 0.0022 | 0.0172 | 0.0506 | |
Echinococcus multilocularis | jun protein | 0.0086 | 0.113 | 0.1144 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0022 | 0.0172 | 0.0172 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0046 | 0.0541 | 0.0541 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0022 | 0.0172 | 0.0174 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0675 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0022 | 0.0172 | 0.0174 |
Brugia malayi | nuclear receptor NHR-88 | 0.0022 | 0.0172 | 0.0172 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0675 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.1095 | 0.2344 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.06 | 0.06 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0667 | 0.9878 | 1 |
Onchocerca volvulus | 0.0067 | 0.0853 | 0.9303 | |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0212 | 0.0453 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0675 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.006 | 0.0744 | 0.0744 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0675 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0228 | 0.3282 | 0.7029 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0019 | 0.0133 | 0.0017 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.005 | 0.06 | 0.0607 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0263 | 0.3809 | 0.3809 |
Echinococcus multilocularis | RUN | 0.0019 | 0.0133 | 0.0135 |
Leishmania major | dihydroorotate dehydrogenase | 0.0675 | 1 | 1 |
Brugia malayi | ecdysone receptor | 0.0022 | 0.0172 | 0.0172 |
Schistosoma mansoni | inositol monophosphatase | 0.0036 | 0.038 | 0.038 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0282 | 0.4093 | 1 |
Brugia malayi | hypothetical protein | 0.0321 | 0.4669 | 0.4669 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0046 | 0.0541 | 0.0548 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0544 | 0.0544 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.038 | 0.038 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0999 | 0.222 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0025 | 0.0223 | 0.0223 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0634 | 0.0634 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0046 | 0.0541 | 0.1159 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0046 | 0.0541 | 0.0541 |
Echinococcus multilocularis | transfer RNA-Lys | 0.0071 | 0.0907 | 0.0919 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0116 | 0.0116 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.026 | 0.026 |
Schistosoma mansoni | polycystin 1-related | 0.0019 | 0.0133 | 0.0133 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Echinococcus multilocularis | tumor protein p63 | 0.0326 | 0.4757 | 0.4815 |
Trichomonas vaginalis | adenylate cyclase, type VII, putative | 0.0025 | 0.0217 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Loa Loa (eye worm) | doublecortin family protein | 0.0019 | 0.0133 | 0.0285 |
Trypanosoma cruzi | STE group serine/threonine-protein kinase, putative | 0.0025 | 0.0223 | 0.0223 |
Onchocerca volvulus | 0.0071 | 0.0907 | 1 | |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.006 | 0.0744 | 0.0753 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.0212 | 0.0212 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0675 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Leishmania major | protein kinase, putative | 0.0025 | 0.0223 | 0.0223 |
Onchocerca volvulus | 0.0022 | 0.0172 | 0.0506 | |
Brugia malayi | nuclear hormone receptor | 0.0046 | 0.0541 | 0.0541 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.0736 | 0.0736 |
Onchocerca volvulus | 0.0025 | 0.0217 | 0.1081 | |
Brugia malayi | bHLH-PAS transcription factor | 0.0071 | 0.0907 | 0.0907 |
Echinococcus granulosus | dnaJ subfamily B | 0.0395 | 0.5791 | 0.5862 |
Brugia malayi | conserved hypotetical protein | 0.0022 | 0.0172 | 0.0172 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0048 | 0.0564 | 0.1208 |
Brugia malayi | nuclear receptor NHR-88 | 0.0046 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.026 | 0.0558 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0999 | 0.222 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.06 | 0.1216 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0046 | 0.0541 | 0.0541 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0046 | 0.0541 | 0.0541 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0019 | 0.0133 | 0.0135 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0675 | 1 | 1 |
Trypanosoma cruzi | STE/STE11 serine/threonine-protein kinase, putative | 0.0025 | 0.0223 | 0.0223 |
Brugia malayi | nuclear receptor RXR | 0.0022 | 0.0172 | 0.0172 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0675 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0172 | 0.0172 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0046 | 0.0541 | 0.5268 |
Schistosoma mansoni | nuclear receptor | 0.0022 | 0.0172 | 0.0172 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0046 | 0.0541 | 0.0541 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0022 | 0.0172 | 0.0506 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Trichomonas vaginalis | CMGC family protein kinase | 0.005 | 0.06 | 0.1216 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0046 | 0.0541 | 0.0548 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.005 | 0.06 | 0.0607 |
Echinococcus granulosus | RUN | 0.0019 | 0.0133 | 0.0135 |
Schistosoma mansoni | loxhd1 | 0.0019 | 0.0133 | 0.0133 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0022 | 0.0172 | 0.0172 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Onchocerca volvulus | 0.0046 | 0.0541 | 0.5268 | |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0544 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Trypanosoma cruzi | PAS-domain containing phosphoglycerate kinase, putative | 0.0025 | 0.0217 | 0.0217 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0077 | 0.0999 | 0.1011 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0022 | 0.0172 | 0.0174 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0046 | 0.0541 | 0.1159 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Echinococcus granulosus | single minded 2 | 0.0071 | 0.0907 | 0.0919 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0133 | 0.0135 |
Trichomonas vaginalis | adenylate cyclase, putative | 0.0025 | 0.0217 | 0.0252 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0263 | 0.3809 | 0.3856 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0116 | 0.0116 |
Schistosoma mansoni | lipoxygenase | 0.0054 | 0.0655 | 0.0655 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0116 | 0.0116 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0086 | 0.113 | 0.1144 |
Schistosoma mansoni | jun-related protein | 0.0069 | 0.0889 | 0.0889 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0172 | 0.0172 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0133 | 0.0135 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0675 | 1 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0046 | 0.0541 | 0.0541 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.005 | 0.06 | 0.06 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0263 | 0.3809 | 0.9286 |
Loa Loa (eye worm) | inositol-1 | 0.0036 | 0.038 | 0.0814 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0046 | 0.0541 | 0.0541 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0046 | 0.0541 | 0.1159 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0022 | 0.0172 | 0.0174 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.005 | 0.06 | 0.06 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.006 | 0.0744 | 0.0744 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.006 | 0.0744 | 0.0744 |
Echinococcus granulosus | Aryl hydrocarbon receptor nuclear | 0.0025 | 0.0217 | 0.0219 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0022 | 0.0172 | 0.0174 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0116 | 0.0116 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.0736 | 0.0736 |
Echinococcus multilocularis | aryl hydrocarbon receptor | 0.0025 | 0.0217 | 0.0219 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0046 | 0.0541 | 0.0548 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0667 | 0.9878 | 1 |
Echinococcus multilocularis | Aryl hydrocarbon receptor nuclear | 0.0025 | 0.0217 | 0.0219 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0025 | 0.0212 | 0.0212 |
Schistosoma mansoni | hypothetical protein | 0.0395 | 0.5791 | 0.5791 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0133 | 0.0285 |
Trichomonas vaginalis | adenylate and guanylate cyclases, putative | 0.0025 | 0.0217 | 0.0252 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0889 | 0.0889 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0212 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0172 | 0.0369 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0054 | 0.0655 | 0.0663 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0025 | 0.0212 | 0.0212 |
Onchocerca volvulus | 0.0047 | 0.0544 | 0.531 | |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0544 | 0.0544 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0133 | 0.0133 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0036 | 0.038 | 0.038 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0263 | 0.3809 | 0.3809 |
Echinococcus granulosus | aryl hydrocarbon receptor | 0.0025 | 0.0217 | 0.0219 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0046 | 0.0541 | 0.0548 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0025 | 0.0212 | 0.0453 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.006 | 0.0744 | 0.0744 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0282 | 0.4093 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0046 | 0.0541 | 0.0548 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0046 | 0.0541 | 0.0541 |
Schistosoma mansoni | nuclear hormone receptor | 0.0022 | 0.0172 | 0.0172 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0046 | 0.0541 | 0.0541 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0022 | 0.0172 | 0.0174 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0025 | 0.0212 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0541 | 0.1159 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0138 | 0.1919 | 0.1919 |
Trichomonas vaginalis | soluble guanylate cyclase gcy, putative | 0.0025 | 0.0217 | 0.0252 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0675 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.06 | 0.06 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Amount of cross-linked protein (functional) | = 2 (ug of cross-linked protein) (mg of protein)-1 | Compound was tested for the induction of HaCaT keratinocyte differentiation at 1 microM expressed as the amount of cross-linked protein in cornified envelope assay | ChEMBL. | 11140730 |
Amount of cross-linked protein (functional) | = 5 (ug of cross-linked protein) (mg of protein)-1 | Compound was tested for the induction of HaCaT keratinocyte differentiation at 5 microM expressed as the amount of cross-linked protein in cornified envelope assay | ChEMBL. | 11140730 |
Amount of cross-linked protein (functional) | = 5.6 (ug of cross-linked protein) (mg of protein)-1 | Compound was tested for the induction of HaCaT keratinocyte differentiation at 10 microM expressed as the amount of cross-linked protein in cornified envelope assay | ChEMBL. | 11140730 |
DD (functional) | = 1.13 uM mM-1 | Deoxyribose degradation measured as hydroxyl radical generation in HaCaT cell at 75 microM of the compound expressed as malondialdehyde released | ChEMBL. | 11140730 |
IC50 (functional) | = 4.2 uM | Antiproliferative activity of the compound against growth of HaCaT cell was determined | ChEMBL. | 11140730 |
LDH release (functional) | = 166 MU | Activity of LDH release in HaCaT cells after treatment with 2 uM concentration of the compound | ChEMBL. | 11140730 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.